SIMILAR PATTERN OF AMINO ACIDS MAPPED TO 'CUO'


List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AM6_A_HAEA555_1
(CARBONIC ANHYDRASE)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		4 / 7 HIS A 491
HIS A 633
HIS A 602
THR A 623
 CUO  A9002 (-3.4A)
CUO  A9002 (-3.3A)
CUO  A9002 (-3.4A)
CUO  A9002 ( 4.5A)
 1.10A 1am6A-4bedA:
undetectable		 1am6A-4bedA:
10.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AM6_A_HAEA555_1
(CARBONIC ANHYDRASE)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		4 / 7 HIS B2974
HIS B3106
HIS B3075
LEU B3093
 CUO  B9008 (-2.9A)
CUO  B9008 (-3.3A)
CUO  B9008 (-2.8A)
None
 0.97A 1am6A-4bedB:
undetectable		 1am6A-4bedB:
9.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AZM_A_AZMA262_1
(CARBONIC ANHYDRASE I)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		4 / 8 HIS A 183
HIS A 179
HIS A 209
HIS A  69
 CUO  A9001 (-3.4A)
CUO  A9001 (-3.4A)
None
CUO  A9001 (-3.1A)
 0.99A 1azmA-4bedA:
undetectable		 1azmA-4bedA:
10.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AZM_A_AZMA262_1
(CARBONIC ANHYDRASE I)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		4 / 8 HIS A 491
HIS A 633
HIS A 602
LEU A 620
 CUO  A9002 (-3.4A)
CUO  A9002 (-3.3A)
CUO  A9002 (-3.4A)
None
 0.94A 1azmA-4bedA:
undetectable		 1azmA-4bedA:
10.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AZM_A_AZMA262_1
(CARBONIC ANHYDRASE I)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		4 / 8 HIS A 905
HIS A1046
HIS A1015
LEU A1033
 CUO  A9003 (-3.5A)
CUO  A9003 (-3.2A)
CUO  A9003 (-3.1A)
None
 1.03A 1azmA-4bedA:
undetectable		 1azmA-4bedA:
10.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AZM_A_AZMA262_1
(CARBONIC ANHYDRASE I)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		4 / 8 HIS A1428
HIS A1424
HIS A1454
HIS A1320
 CUO  A9004 (-3.4A)
CUO  A9004 (-3.0A)
None
CUO  A9004 (-3.5A)
 1.05A 1azmA-4bedA:
undetectable		 1azmA-4bedA:
10.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AZM_A_AZMA262_1
(CARBONIC ANHYDRASE I)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		4 / 8 HIS B1851
HIS B1847
HIS B1877
HIS B1734
 CUO  B9005 (-3.2A)
CUO  B9005 (-3.2A)
None
CUO  B9005 (-3.4A)
 1.03A 1azmA-4bedB:
undetectable		 1azmA-4bedB:
9.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AZM_A_AZMA262_1
(CARBONIC ANHYDRASE I)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		4 / 8 HIS B2264
HIS B2260
HIS B2290
HIS B2150
 CUO  B9006 (-3.2A)
CUO  B9006 (-3.2A)
None
CUO  B9006 (-3.3A)
 1.01A 1azmA-4bedB:
undetectable		 1azmA-4bedB:
9.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AZM_A_AZMA262_1
(CARBONIC ANHYDRASE I)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		4 / 8 HIS B2570
HIS B2701
HIS B2670
LEU B2688
 CUO  B9007 (-3.3A)
CUO  B9007 (-3.1A)
CUO  B9007 (-3.4A)
None
 0.99A 1azmA-4bedB:
undetectable		 1azmA-4bedB:
9.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AZM_A_AZMA262_1
(CARBONIC ANHYDRASE I)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		4 / 8 HIS B2674
HIS B2670
HIS B2700
HIS B2570
 CUO  B9007 (-3.4A)
CUO  B9007 (-3.4A)
None
CUO  B9007 (-3.3A)
 1.05A 1azmA-4bedB:
undetectable		 1azmA-4bedB:
9.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AZM_A_AZMA262_1
(CARBONIC ANHYDRASE I)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		4 / 8 PHE B1741
HIS B1878
HIS B1847
HIS B1734
 None
CUO  B9005 (-3.3A)
CUO  B9005 (-3.2A)
CUO  B9005 (-3.4A)
 1.06A 1azmA-4bedB:
undetectable		 1azmA-4bedB:
9.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1BZM_A_MZMA262_1
(CARBONIC ANHYDRASE I)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		5 / 8 HIS A  42
HIS A 210
HIS A  69
LEU A 344
HIS A 183
 CUO  A9001 (-3.4A)
CUO  A9001 (-3.3A)
CUO  A9001 (-3.1A)
None
CUO  A9001 (-3.4A)
 1.36A 1bzmA-4bedA:
undetectable		 1bzmA-4bedA:
10.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1BZM_A_MZMA262_1
(CARBONIC ANHYDRASE I)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		4 / 8 HIS A 183
HIS A 179
HIS A 209
HIS A  69
 CUO  A9001 (-3.4A)
CUO  A9001 (-3.4A)
None
CUO  A9001 (-3.1A)
 0.99A 1bzmA-4bedA:
undetectable		 1bzmA-4bedA:
10.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1BZM_A_MZMA262_1
(CARBONIC ANHYDRASE I)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		4 / 8 HIS A 210
HIS A 179
HIS A  69
HIS A 183
 CUO  A9001 (-3.3A)
CUO  A9001 (-3.4A)
CUO  A9001 (-3.1A)
CUO  A9001 (-3.4A)
 1.00A 1bzmA-4bedA:
undetectable		 1bzmA-4bedA:
10.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1BZM_A_MZMA262_1
(CARBONIC ANHYDRASE I)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		5 / 8 HIS A 491
HIS A 633
HIS A 602
LEU A 620
HIS A 462
 CUO  A9002 (-3.4A)
CUO  A9002 (-3.3A)
CUO  A9002 (-3.4A)
None
CUO  A9002 (-3.2A)
 1.09A 1bzmA-4bedA:
undetectable		 1bzmA-4bedA:
10.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1BZM_A_MZMA262_1
(CARBONIC ANHYDRASE I)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		4 / 8 HIS A 633
HIS A 602
HIS A 491
HIS A 606
 CUO  A9002 (-3.3A)
CUO  A9002 (-3.4A)
CUO  A9002 (-3.4A)
CUO  A9002 (-3.3A)
 0.86A 1bzmA-4bedA:
undetectable		 1bzmA-4bedA:
10.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1BZM_A_MZMA262_1
(CARBONIC ANHYDRASE I)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		4 / 8 HIS A1046
HIS A1015
HIS A 905
HIS A1019
 CUO  A9003 (-3.2A)
CUO  A9003 (-3.1A)
CUO  A9003 (-3.5A)
CUO  A9003 (-3.4A)
 0.96A 1bzmA-4bedA:
undetectable		 1bzmA-4bedA:
10.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1BZM_A_MZMA262_1
(CARBONIC ANHYDRASE I)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		4 / 8 HIS B1878
HIS B1847
HIS B1734
HIS B1851
 CUO  B9005 (-3.3A)
CUO  B9005 (-3.2A)
CUO  B9005 (-3.4A)
CUO  B9005 (-3.2A)
 0.97A 1bzmA-4bedB:
undetectable		 1bzmA-4bedB:
9.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1BZM_A_MZMA262_1
(CARBONIC ANHYDRASE I)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		4 / 8 HIS B2264
HIS B2260
HIS B2290
HIS B2150
 CUO  B9006 (-3.2A)
CUO  B9006 (-3.2A)
None
CUO  B9006 (-3.3A)
 0.98A 1bzmA-4bedB:
undetectable		 1bzmA-4bedB:
9.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1BZM_A_MZMA262_1
(CARBONIC ANHYDRASE I)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		4 / 8 HIS B2570
HIS B2701
HIS B2670
LEU B2688
 CUO  B9007 (-3.3A)
CUO  B9007 (-3.1A)
CUO  B9007 (-3.4A)
None
 1.00A 1bzmA-4bedB:
undetectable		 1bzmA-4bedB:
9.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1BZM_A_MZMA262_1
(CARBONIC ANHYDRASE I)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		4 / 8 HIS B2701
HIS B2670
HIS B2570
HIS B2674
 CUO  B9007 (-3.1A)
CUO  B9007 (-3.4A)
CUO  B9007 (-3.3A)
CUO  B9007 (-3.4A)
 0.96A 1bzmA-4bedB:
undetectable		 1bzmA-4bedB:
9.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1BZM_A_MZMA262_1
(CARBONIC ANHYDRASE I)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		4 / 8 HIS B3106
HIS B3075
HIS B2974
HIS B3079
 CUO  B9008 (-3.3A)
CUO  B9008 (-2.8A)
CUO  B9008 (-2.9A)
CUO  B9008 (-3.5A)
 0.93A 1bzmA-4bedB:
undetectable		 1bzmA-4bedB:
9.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1D4F_B_ADNB602_2
(S-ADENOSYLHOMOCYSTEI
NE HYDROLASE)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		4 / 5 THR B1881
GLU B1840
THR B1729
HIS B1725
 None
None
None
CUO  B9005 (-3.1A)
 1.36A 1d4fB-4bedB:
undetectable		 1d4fB-4bedB:
13.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1D4F_B_ADNB602_2
(S-ADENOSYLHOMOCYSTEI
NE HYDROLASE)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		4 / 5 THR B2704
GLU B2663
THR B2565
HIS B2561
 None
None
None
CUO  B9007 (-3.3A)
 1.26A 1d4fB-4bedB:
undetectable		 1d4fB-4bedB:
13.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DMY_A_AZMA400_1
(MURINE CARBONIC
ANHYDRASE V)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		5 / 11 HIS A 179
HIS A 210
VAL A  73
TYR A 275
LEU A  89
 CUO  A9001 (-3.4A)
CUO  A9001 (-3.3A)
None
None
None
 1.02A 1dmyA-4bedA:
undetectable		 1dmyA-4bedA:
9.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IE9_A_VDXA500_1
(VITAMIN D3 RECEPTOR)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		5 / 12 LEU B1873
LEU B1770
VAL B1850
HIS B1851
HIS B1878
 None
None
None
CUO  B9005 (-3.2A)
CUO  B9005 (-3.3A)
 1.35A 1ie9A-4bedB:
undetectable		 1ie9A-4bedB:
10.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OS2_A_HAEA874_1
(MACROPHAGE
METALLOELASTASE)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		4 / 5 HIS A 632
HIS A 482
HIS A 491
HIS A 462
 None
CUO  A9002 (-3.4A)
CUO  A9002 (-3.4A)
CUO  A9002 (-3.2A)
 1.11A 1os2A-4bedA:
undetectable		 1os2A-4bedA:
6.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OS2_A_HAEA874_1
(MACROPHAGE
METALLOELASTASE)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		4 / 5 HIS B1877
HIS B1725
HIS B1734
HIS B1705
 None
CUO  B9005 (-3.1A)
CUO  B9005 (-3.4A)
CUO  B9005 (-3.2A)
 1.07A 1os2A-4bedB:
undetectable		 1os2A-4bedB:
7.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_B_FUAB703_2
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		3 / 3 VAL B2136
ALA B2137
HIS B2122
 None
None
CUO  B9006 (-3.2A)
 0.69A 1q23C-4bedB:
undetectable		 1q23C-4bedB:
8.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_G_FUAG708_2
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		3 / 3 VAL B2136
ALA B2137
HIS B2122
 None
None
CUO  B9006 (-3.2A)
 0.58A 1q23H-4bedB:
undetectable		 1q23H-4bedB:
8.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_I_FUAI707_1
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		3 / 3 VAL B2136
ALA B2137
HIS B2122
 None
None
CUO  B9006 (-3.2A)
 0.70A 1q23G-4bedB:
undetectable		 1q23G-4bedB:
8.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_K_FUAK712_2
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		3 / 3 VAL B2136
ALA B2137
HIS B2122
 None
None
CUO  B9006 (-3.2A)
 0.77A 1q23L-4bedB:
undetectable		 1q23L-4bedB:
8.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_L_FUAL710_1
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		3 / 3 VAL B2136
ALA B2137
HIS B2122
 None
None
CUO  B9006 (-3.2A)
 0.63A 1q23J-4bedB:
undetectable		 1q23J-4bedB:
8.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1R55_A_097A518_1
(ADAM 33)		 1js8 HEMOCYANIN
(Enteroctopus
dofleini) 		5 / 10 VAL A2678
HIS A2701
HIS A2702
HIS A2671
ALA A2673
 None
None
CUO  A 888 (-3.3A)
CUO  A 888 (-3.4A)
None
 1.16A 1r55A-1js8A:
undetectable		 1r55A-1js8A:
21.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1R55_A_097A518_1
(ADAM 33)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		5 / 10 ALA A 892
HIS A1046
HIS A1015
HIS A1019
ALA A1037
 None
CUO  A9003 (-3.2A)
CUO  A9003 (-3.1A)
CUO  A9003 (-3.4A)
None
 1.24A 1r55A-4bedA:
undetectable		 1r55A-4bedA:
8.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1R55_A_097A518_1
(ADAM 33)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		5 / 10 HIS B2670
HIS B2701
HIS B2674
ALA B2672
THR B2669
 CUO  B9007 (-3.4A)
CUO  B9007 (-3.1A)
CUO  B9007 (-3.4A)
None
None
 1.15A 1r55A-4bedB:
undetectable		 1r55A-4bedB:
8.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1R55_A_097A518_1
(ADAM 33)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		5 / 10 VAL A 186
HIS A 209
HIS A 210
HIS A 179
ALA A 181
 None
None
CUO  A9001 (-3.3A)
CUO  A9001 (-3.4A)
None
 1.22A 1r55A-4bedA:
undetectable		 1r55A-4bedA:
8.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RJO_A_CUA701_0
(PHENYLETHYLAMINE
OXIDASE)		 1js8 HEMOCYANIN
(Enteroctopus
dofleini) 		3 / 3 HIS A2702
HIS A2671
HIS A2571
 CUO  A 888 (-3.3A)
CUO  A 888 (-3.4A)
CUO  A 888 (-3.3A)
 0.67A 1rjoA-1js8A:
undetectable		 1rjoA-1js8A:
20.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RJO_A_CUA701_0
(PHENYLETHYLAMINE
OXIDASE)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		3 / 3 HIS A 210
HIS A 179
HIS A  69
 CUO  A9001 (-3.3A)
CUO  A9001 (-3.4A)
CUO  A9001 (-3.1A)
 0.67A 1rjoA-4bedA:
undetectable		 1rjoA-4bedA:
17.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RJO_A_CUA701_0
(PHENYLETHYLAMINE
OXIDASE)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		3 / 3 HIS A1455
HIS A1424
HIS A1320
 CUO  A9004 (-3.3A)
CUO  A9004 (-3.0A)
CUO  A9004 (-3.5A)
 0.69A 1rjoA-4bedA:
undetectable		 1rjoA-4bedA:
17.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RJO_A_CUA701_0
(PHENYLETHYLAMINE
OXIDASE)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		3 / 3 HIS B1878
HIS B1847
HIS B1734
 CUO  B9005 (-3.3A)
CUO  B9005 (-3.2A)
CUO  B9005 (-3.4A)
 0.65A 1rjoA-4bedB:
undetectable		 1rjoA-4bedB:
17.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RJO_A_CUA701_0
(PHENYLETHYLAMINE
OXIDASE)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		3 / 3 HIS B2291
HIS B2260
HIS B2150
 CUO  B9006 (-3.5A)
CUO  B9006 (-3.2A)
CUO  B9006 (-3.3A)
 0.70A 1rjoA-4bedB:
undetectable		 1rjoA-4bedB:
17.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RJO_A_CUA701_0
(PHENYLETHYLAMINE
OXIDASE)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		3 / 3 HIS B2701
HIS B2670
HIS B2570
 CUO  B9007 (-3.1A)
CUO  B9007 (-3.4A)
CUO  B9007 (-3.3A)
 0.69A 1rjoA-4bedB:
undetectable		 1rjoA-4bedB:
17.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RKY_A_CUA801_0
(LYSYL OXIDASE)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		3 / 3 HIS B1878
HIS B1847
HIS B1734
 CUO  B9005 (-3.3A)
CUO  B9005 (-3.2A)
CUO  B9005 (-3.4A)
 0.68A 1rkyA-4bedB:
undetectable		 1rkyA-4bedB:
18.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V54_A_CUA517_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		3 / 3 HIS B2946
HIS B3106
HIS B2974
 CUO  B9008 (-3.1A)
CUO  B9008 (-3.3A)
CUO  B9008 (-2.9A)
 0.67A 1v54A-4bedB:
undetectable		 1v54A-4bedB:
14.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V54_N_CUN517_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		3 / 3 HIS B2946
HIS B3106
HIS B2974
 CUO  B9008 (-3.1A)
CUO  B9008 (-3.3A)
CUO  B9008 (-2.9A)
 0.69A 1v54N-4bedB:
undetectable		 1v54N-4bedB:
14.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V55_A_CUA517_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		3 / 3 HIS B2946
HIS B3106
HIS B2974
 CUO  B9008 (-3.1A)
CUO  B9008 (-3.3A)
CUO  B9008 (-2.9A)
 0.66A 1v55A-4bedB:
undetectable		 1v55A-4bedB:
14.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V55_N_CUN517_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		3 / 3 HIS B2946
HIS B3106
HIS B2974
 CUO  B9008 (-3.1A)
CUO  B9008 (-3.3A)
CUO  B9008 (-2.9A)
 0.66A 1v55N-4bedB:
undetectable		 1v55N-4bedB:
14.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1W2Z_A_CUA701_0
(AMINE OXIDASE,
COPPER CONTAINING)		 1js8 HEMOCYANIN
(Enteroctopus
dofleini) 		3 / 3 HIS A2702
HIS A2671
HIS A2571
 CUO  A 888 (-3.3A)
CUO  A 888 (-3.4A)
CUO  A 888 (-3.3A)
 0.70A 1w2zA-1js8A:
undetectable		 1w2zA-1js8A:
19.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1W2Z_A_CUA701_0
(AMINE OXIDASE,
COPPER CONTAINING)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		3 / 3 HIS A 210
HIS A 179
HIS A  69
 CUO  A9001 (-3.3A)
CUO  A9001 (-3.4A)
CUO  A9001 (-3.1A)
 0.73A 1w2zA-4bedA:
undetectable		 1w2zA-4bedA:
16.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1W2Z_A_CUA701_0
(AMINE OXIDASE,
COPPER CONTAINING)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		3 / 3 HIS B1878
HIS B1847
HIS B1734
 CUO  B9005 (-3.3A)
CUO  B9005 (-3.2A)
CUO  B9005 (-3.4A)
 0.69A 1w2zA-4bedB:
undetectable		 1w2zA-4bedB:
16.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1W2Z_A_CUA701_0
(AMINE OXIDASE,
COPPER CONTAINING)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		3 / 3 HIS B2701
HIS B2670
HIS B2570
 CUO  B9007 (-3.1A)
CUO  B9007 (-3.4A)
CUO  B9007 (-3.3A)
 0.72A 1w2zA-4bedB:
undetectable		 1w2zA-4bedB:
16.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1W2Z_B_CUB701_0
(AMINE OXIDASE,
COPPER CONTAINING)		 1js8 HEMOCYANIN
(Enteroctopus
dofleini) 		3 / 3 HIS A2702
HIS A2671
HIS A2571
 CUO  A 888 (-3.3A)
CUO  A 888 (-3.4A)
CUO  A 888 (-3.3A)
 0.71A 1w2zB-1js8A:
undetectable		 1w2zB-1js8A:
19.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1W2Z_B_CUB701_0
(AMINE OXIDASE,
COPPER CONTAINING)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		3 / 3 HIS A 210
HIS A 179
HIS A  69
 CUO  A9001 (-3.3A)
CUO  A9001 (-3.4A)
CUO  A9001 (-3.1A)
 0.69A 1w2zB-4bedA:
undetectable		 1w2zB-4bedA:
16.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1W2Z_B_CUB701_0
(AMINE OXIDASE,
COPPER CONTAINING)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		3 / 3 HIS A1455
HIS A1424
HIS A1320
 CUO  A9004 (-3.3A)
CUO  A9004 (-3.0A)
CUO  A9004 (-3.5A)
 0.71A 1w2zB-4bedA:
undetectable		 1w2zB-4bedA:
16.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1W2Z_B_CUB701_0
(AMINE OXIDASE,
COPPER CONTAINING)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		3 / 3 HIS B1878
HIS B1847
HIS B1734
 CUO  B9005 (-3.3A)
CUO  B9005 (-3.2A)
CUO  B9005 (-3.4A)
 0.65A 1w2zB-4bedB:
undetectable		 1w2zB-4bedB:
16.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1W2Z_B_CUB701_0
(AMINE OXIDASE,
COPPER CONTAINING)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		3 / 3 HIS B2291
HIS B2260
HIS B2150
 CUO  B9006 (-3.5A)
CUO  B9006 (-3.2A)
CUO  B9006 (-3.3A)
 0.71A 1w2zB-4bedB:
undetectable		 1w2zB-4bedB:
16.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1W2Z_B_CUB701_0
(AMINE OXIDASE,
COPPER CONTAINING)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		3 / 3 HIS B2701
HIS B2670
HIS B2570
 CUO  B9007 (-3.1A)
CUO  B9007 (-3.4A)
CUO  B9007 (-3.3A)
 0.67A 1w2zB-4bedB:
undetectable		 1w2zB-4bedB:
16.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1W2Z_B_CUB701_0
(AMINE OXIDASE,
COPPER CONTAINING)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		3 / 3 HIS B3106
HIS B3075
HIS B2974
 CUO  B9008 (-3.3A)
CUO  B9008 (-2.8A)
CUO  B9008 (-2.9A)
 0.72A 1w2zB-4bedB:
undetectable		 1w2zB-4bedB:
16.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1W2Z_C_CUC701_0
(AMINE OXIDASE,
COPPER CONTAINING)		 1js8 HEMOCYANIN
(Enteroctopus
dofleini) 		3 / 3 HIS A2702
HIS A2671
HIS A2571
 CUO  A 888 (-3.3A)
CUO  A 888 (-3.4A)
CUO  A 888 (-3.3A)
 0.70A 1w2zC-1js8A:
undetectable		 1w2zC-1js8A:
19.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1W2Z_C_CUC701_0
(AMINE OXIDASE,
COPPER CONTAINING)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		3 / 3 HIS A 210
HIS A 179
HIS A  69
 CUO  A9001 (-3.3A)
CUO  A9001 (-3.4A)
CUO  A9001 (-3.1A)
 0.68A 1w2zC-4bedA:
undetectable		 1w2zC-4bedA:
16.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1W2Z_C_CUC701_0
(AMINE OXIDASE,
COPPER CONTAINING)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		3 / 3 HIS A1455
HIS A1424
HIS A1320
 CUO  A9004 (-3.3A)
CUO  A9004 (-3.0A)
CUO  A9004 (-3.5A)
 0.69A 1w2zC-4bedA:
undetectable		 1w2zC-4bedA:
16.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1W2Z_C_CUC701_0
(AMINE OXIDASE,
COPPER CONTAINING)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		3 / 3 HIS B1878
HIS B1847
HIS B1734
 CUO  B9005 (-3.3A)
CUO  B9005 (-3.2A)
CUO  B9005 (-3.4A)
 0.64A 1w2zC-4bedB:
undetectable		 1w2zC-4bedB:
16.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1W2Z_C_CUC701_0
(AMINE OXIDASE,
COPPER CONTAINING)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		3 / 3 HIS B2291
HIS B2260
HIS B2150
 CUO  B9006 (-3.5A)
CUO  B9006 (-3.2A)
CUO  B9006 (-3.3A)
 0.71A 1w2zC-4bedB:
undetectable		 1w2zC-4bedB:
16.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1W2Z_C_CUC701_0
(AMINE OXIDASE,
COPPER CONTAINING)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		3 / 3 HIS B2701
HIS B2670
HIS B2570
 CUO  B9007 (-3.1A)
CUO  B9007 (-3.4A)
CUO  B9007 (-3.3A)
 0.67A 1w2zC-4bedB:
undetectable		 1w2zC-4bedB:
16.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1W2Z_D_CUD701_0
(AMINE OXIDASE,
COPPER CONTAINING)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		3 / 3 HIS A 210
HIS A 179
HIS A  69
 CUO  A9001 (-3.3A)
CUO  A9001 (-3.4A)
CUO  A9001 (-3.1A)
 0.68A 1w2zD-4bedA:
undetectable		 1w2zD-4bedA:
16.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1W2Z_D_CUD701_0
(AMINE OXIDASE,
COPPER CONTAINING)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		3 / 3 HIS A1455
HIS A1424
HIS A1320
 CUO  A9004 (-3.3A)
CUO  A9004 (-3.0A)
CUO  A9004 (-3.5A)
 0.69A 1w2zD-4bedA:
undetectable		 1w2zD-4bedA:
16.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1W2Z_D_CUD701_0
(AMINE OXIDASE,
COPPER CONTAINING)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		3 / 3 HIS B1878
HIS B1847
HIS B1734
 CUO  B9005 (-3.3A)
CUO  B9005 (-3.2A)
CUO  B9005 (-3.4A)
 0.63A 1w2zD-4bedB:
undetectable		 1w2zD-4bedB:
16.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1W2Z_D_CUD701_0
(AMINE OXIDASE,
COPPER CONTAINING)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		3 / 3 HIS B2291
HIS B2260
HIS B2150
 CUO  B9006 (-3.5A)
CUO  B9006 (-3.2A)
CUO  B9006 (-3.3A)
 0.69A 1w2zD-4bedB:
undetectable		 1w2zD-4bedB:
16.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1W2Z_D_CUD701_0
(AMINE OXIDASE,
COPPER CONTAINING)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		3 / 3 HIS B2701
HIS B2670
HIS B2570
 CUO  B9007 (-3.1A)
CUO  B9007 (-3.4A)
CUO  B9007 (-3.3A)
 0.66A 1w2zD-4bedB:
undetectable		 1w2zD-4bedB:
16.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XLX_A_CIOA101_1
(CAMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE 4B)		 1js8 HEMOCYANIN
(Enteroctopus
dofleini) 		5 / 12 HIS A2671
LEU A2574
THR A2566
MET A2564
GLN A2561
 CUO  A 888 (-3.4A)
None
None
None
None
 1.31A 1xlxA-1js8A:
undetectable		 1xlxA-1js8A:
21.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XOM_B_CIOB601_1
(CAMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE 4D)		 1js8 HEMOCYANIN
(Enteroctopus
dofleini) 		5 / 12 HIS A2671
LEU A2574
THR A2566
MET A2564
GLN A2561
 CUO  A 888 (-3.4A)
None
None
None
None
 1.30A 1xomB-1js8A:
undetectable		 1xomB-1js8A:
23.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YVM_A_TMGA501_1
(METHIONINE
AMINOPEPTIDASE)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		4 / 7 TYR A1323
HIS A1293
HIS A1428
TRP A1319
 None
CUO  A9004 (-3.2A)
CUO  A9004 (-3.4A)
None
 1.46A 1yvmA-4bedA:
undetectable		 1yvmA-4bedA:
9.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YVM_A_TMGA501_1
(METHIONINE
AMINOPEPTIDASE)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		4 / 7 TYR B1737
HIS B1705
HIS B1851
TRP B1733
 None
CUO  B9005 (-3.2A)
CUO  B9005 (-3.2A)
None
 1.45A 1yvmA-4bedB:
undetectable		 1yvmA-4bedB:
9.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYR_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		3 / 3 HIS B2946
HIS B3106
HIS B2974
 CUO  B9008 (-3.1A)
CUO  B9008 (-3.3A)
CUO  B9008 (-2.9A)
 0.67A 2dyrA-4bedB:
undetectable		 2dyrA-4bedB:
14.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYR_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		4 / 7 ASP B3030
THR B3031
TYR B3088
HIS B3106
 None
None
None
CUO  B9008 (-3.3A)
 1.50A 2dyrA-4bedB:
undetectable
2dyrC-4bedB:
undetectable		 2dyrA-4bedB:
14.43
2dyrC-4bedB:
9.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYR_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		3 / 3 HIS B2946
HIS B3106
HIS B2974
 CUO  B9008 (-3.1A)
CUO  B9008 (-3.3A)
CUO  B9008 (-2.9A)
 0.70A 2dyrN-4bedB:
undetectable		 2dyrN-4bedB:
14.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYS_A_CUA601_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		3 / 3 HIS B2946
HIS B3106
HIS B2974
 CUO  B9008 (-3.1A)
CUO  B9008 (-3.3A)
CUO  B9008 (-2.9A)
 0.72A 2dysA-4bedB:
undetectable		 2dysA-4bedB:
14.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYS_C_CHDC304_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1js8 HEMOCYANIN
(Enteroctopus
dofleini) 		4 / 6 HIS A2562
ASP A2695
THR A2692
TYR A2691
 CUO  A 888 (-3.4A)
None
CUO  A 888 ( 4.9A)
None
 1.23A 2dysA-1js8A:
undetectable
2dysC-1js8A:
1.0		 2dysA-1js8A:
21.26
2dysC-1js8A:
22.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYS_C_CHDC304_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		4 / 6 HIS A 482
ASP A 626
THR A 623
TYR A 622
 CUO  A9002 (-3.4A)
None
CUO  A9002 ( 4.5A)
None
 1.17A 2dysA-4bedA:
undetectable
2dysC-4bedA:
undetectable		 2dysA-4bedA:
14.65
2dysC-4bedA:
9.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYS_N_CUN601_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		3 / 3 HIS B2946
HIS B3106
HIS B2974
 CUO  B9008 (-3.1A)
CUO  B9008 (-3.3A)
CUO  B9008 (-2.9A)
 0.73A 2dysN-4bedB:
undetectable		 2dysN-4bedB:
14.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIJ_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		3 / 3 HIS B2946
HIS B3106
HIS B2974
 CUO  B9008 (-3.1A)
CUO  B9008 (-3.3A)
CUO  B9008 (-2.9A)
 0.65A 2eijA-4bedB:
0.2		 2eijA-4bedB:
14.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIJ_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		3 / 3 HIS B2946
HIS B3106
HIS B2974
 CUO  B9008 (-3.1A)
CUO  B9008 (-3.3A)
CUO  B9008 (-2.9A)
 0.66A 2eijN-4bedB:
undetectable		 2eijN-4bedB:
14.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIK_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		3 / 3 HIS B2946
HIS B3106
HIS B2974
 CUO  B9008 (-3.1A)
CUO  B9008 (-3.3A)
CUO  B9008 (-2.9A)
 0.65A 2eikA-4bedB:
undetectable		 2eikA-4bedB:
14.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIK_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		3 / 3 HIS B2946
HIS B3106
HIS B2974
 CUO  B9008 (-3.1A)
CUO  B9008 (-3.3A)
CUO  B9008 (-2.9A)
 0.69A 2eikN-4bedB:
undetectable		 2eikN-4bedB:
14.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIL_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		3 / 3 HIS B2946
HIS B3106
HIS B2974
 CUO  B9008 (-3.1A)
CUO  B9008 (-3.3A)
CUO  B9008 (-2.9A)
 0.68A 2eilA-4bedB:
undetectable		 2eilA-4bedB:
14.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIL_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1js8 HEMOCYANIN
(Enteroctopus
dofleini) 		4 / 7 HIS A2562
ASP A2695
THR A2692
TYR A2691
 CUO  A 888 (-3.4A)
None
CUO  A 888 ( 4.9A)
None
 1.22A 2eilA-1js8A:
undetectable
2eilC-1js8A:
1.2		 2eilA-1js8A:
21.26
2eilC-1js8A:
22.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIL_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		4 / 7 HIS A 482
ASP A 626
THR A 623
TYR A 622
 CUO  A9002 (-3.4A)
None
CUO  A9002 ( 4.5A)
None
 1.15A 2eilA-4bedA:
undetectable
2eilC-4bedA:
undetectable		 2eilA-4bedA:
14.65
2eilC-4bedA:
9.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIL_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		3 / 3 HIS B2946
HIS B3106
HIS B2974
 CUO  B9008 (-3.1A)
CUO  B9008 (-3.3A)
CUO  B9008 (-2.9A)
 0.70A 2eilN-4bedB:
undetectable		 2eilN-4bedB:
14.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIM_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		3 / 3 HIS B2946
HIS B3106
HIS B2974
 CUO  B9008 (-3.1A)
CUO  B9008 (-3.3A)
CUO  B9008 (-2.9A)
 0.67A 2eimA-4bedB:
undetectable		 2eimA-4bedB:
14.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIM_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		3 / 3 HIS B2946
HIS B3106
HIS B2974
 CUO  B9008 (-3.1A)
CUO  B9008 (-3.3A)
CUO  B9008 (-2.9A)
 0.68A 2eimN-4bedB:
undetectable		 2eimN-4bedB:
14.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FQE_A_CUA603_0
(BLUE COPPER OXIDASE
CUEO)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		4 / 4 HIS A 179
HIS A  69
HIS A 210
HIS A 209
 CUO  A9001 (-3.4A)
CUO  A9001 (-3.1A)
CUO  A9001 (-3.3A)
None
 1.34A 2fqeA-4bedA:
undetectable		 2fqeA-4bedA:
15.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FQE_A_CUA603_0
(BLUE COPPER OXIDASE
CUEO)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		4 / 4 HIS B2260
HIS B2150
HIS B2291
HIS B2290
 CUO  B9006 (-3.2A)
CUO  B9006 (-3.3A)
CUO  B9006 (-3.5A)
None
 1.37A 2fqeA-4bedB:
undetectable		 2fqeA-4bedB:
15.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FQF_A_CUA603_0
(BLUE COPPER OXIDASE
CUEO)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		4 / 4 HIS A 179
HIS A  69
HIS A 210
HIS A 209
 CUO  A9001 (-3.4A)
CUO  A9001 (-3.1A)
CUO  A9001 (-3.3A)
None
 1.38A 2fqfA-4bedA:
undetectable		 2fqfA-4bedA:
15.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HC4_A_VDXA525_1
(VITAMIN D RECEPTOR)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		5 / 12 VAL B3078
HIS B3075
LEU B3109
HIS B3106
LEU B3236
 None
CUO  B9008 (-2.8A)
None
CUO  B9008 (-3.3A)
None
 1.38A 2hc4A-4bedB:
undetectable		 2hc4A-4bedB:
11.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IT4_A_PPFA500_1
(CARBONIC ANHYDRASE 1)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		5 / 8 HIS A  42
HIS A  69
ALA A  56
LEU A 344
HIS A 183
 CUO  A9001 (-3.4A)
CUO  A9001 (-3.1A)
None
None
CUO  A9001 (-3.4A)
 1.23A 2it4A-4bedA:
undetectable		 2it4A-4bedA:
10.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OQE_A_CUA801_0
(PEROXISOMAL COPPER
AMINE OXIDASE)		 1js8 HEMOCYANIN
(Enteroctopus
dofleini) 		3 / 3 HIS A2702
HIS A2671
HIS A2571
 CUO  A 888 (-3.3A)
CUO  A 888 (-3.4A)
CUO  A 888 (-3.3A)
 0.71A 2oqeA-1js8A:
undetectable		 2oqeA-1js8A:
19.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OQE_A_CUA801_0
(PEROXISOMAL COPPER
AMINE OXIDASE)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		3 / 3 HIS A 210
HIS A 179
HIS A  69
 CUO  A9001 (-3.3A)
CUO  A9001 (-3.4A)
CUO  A9001 (-3.1A)
 0.70A 2oqeA-4bedA:
undetectable		 2oqeA-4bedA:
17.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OQE_A_CUA801_0
(PEROXISOMAL COPPER
AMINE OXIDASE)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		3 / 3 HIS A1455
HIS A1424
HIS A1320
 CUO  A9004 (-3.3A)
CUO  A9004 (-3.0A)
CUO  A9004 (-3.5A)
 0.71A 2oqeA-4bedA:
undetectable		 2oqeA-4bedA:
17.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OQE_A_CUA801_0
(PEROXISOMAL COPPER
AMINE OXIDASE)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		3 / 3 HIS B1878
HIS B1847
HIS B1734
 CUO  B9005 (-3.3A)
CUO  B9005 (-3.2A)
CUO  B9005 (-3.4A)
 0.67A 2oqeA-4bedB:
undetectable		 2oqeA-4bedB:
17.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OQE_A_CUA801_0
(PEROXISOMAL COPPER
AMINE OXIDASE)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		3 / 3 HIS B2291
HIS B2260
HIS B2150
 CUO  B9006 (-3.5A)
CUO  B9006 (-3.2A)
CUO  B9006 (-3.3A)
 0.72A 2oqeA-4bedB:
undetectable		 2oqeA-4bedB:
17.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OQE_A_CUA801_0
(PEROXISOMAL COPPER
AMINE OXIDASE)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		3 / 3 HIS B2701
HIS B2670
HIS B2570
 CUO  B9007 (-3.1A)
CUO  B9007 (-3.4A)
CUO  B9007 (-3.3A)
 0.71A 2oqeA-4bedB:
undetectable		 2oqeA-4bedB:
17.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OQE_B_CUB801_0
(PEROXISOMAL COPPER
AMINE OXIDASE)		 1js8 HEMOCYANIN
(Enteroctopus
dofleini) 		3 / 3 HIS A2702
HIS A2671
HIS A2571
 CUO  A 888 (-3.3A)
CUO  A 888 (-3.4A)
CUO  A 888 (-3.3A)
 0.71A 2oqeB-1js8A:
undetectable		 2oqeB-1js8A:
19.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OQE_B_CUB801_0
(PEROXISOMAL COPPER
AMINE OXIDASE)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		3 / 3 HIS A 210
HIS A 179
HIS A  69
 CUO  A9001 (-3.3A)
CUO  A9001 (-3.4A)
CUO  A9001 (-3.1A)
 0.69A 2oqeB-4bedA:
undetectable		 2oqeB-4bedA:
17.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OQE_B_CUB801_0
(PEROXISOMAL COPPER
AMINE OXIDASE)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		3 / 3 HIS A1455
HIS A1424
HIS A1320
 CUO  A9004 (-3.3A)
CUO  A9004 (-3.0A)
CUO  A9004 (-3.5A)
 0.70A 2oqeB-4bedA:
undetectable		 2oqeB-4bedA:
17.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OQE_B_CUB801_0
(PEROXISOMAL COPPER
AMINE OXIDASE)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		3 / 3 HIS B1878
HIS B1847
HIS B1734
 CUO  B9005 (-3.3A)
CUO  B9005 (-3.2A)
CUO  B9005 (-3.4A)
 0.67A 2oqeB-4bedB:
undetectable		 2oqeB-4bedB:
17.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OQE_B_CUB801_0
(PEROXISOMAL COPPER
AMINE OXIDASE)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		3 / 3 HIS B2291
HIS B2260
HIS B2150
 CUO  B9006 (-3.5A)
CUO  B9006 (-3.2A)
CUO  B9006 (-3.3A)
 0.71A 2oqeB-4bedB:
undetectable		 2oqeB-4bedB:
17.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OQE_B_CUB801_0
(PEROXISOMAL COPPER
AMINE OXIDASE)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		3 / 3 HIS B2701
HIS B2670
HIS B2570
 CUO  B9007 (-3.1A)
CUO  B9007 (-3.4A)
CUO  B9007 (-3.3A)
 0.71A 2oqeB-4bedB:
undetectable		 2oqeB-4bedB:
17.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OQE_C_CUC801_0
(PEROXISOMAL COPPER
AMINE OXIDASE)		 1js8 HEMOCYANIN
(Enteroctopus
dofleini) 		3 / 3 HIS A2702
HIS A2671
HIS A2571
 CUO  A 888 (-3.3A)
CUO  A 888 (-3.4A)
CUO  A 888 (-3.3A)
 0.70A 2oqeC-1js8A:
undetectable		 2oqeC-1js8A:
19.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OQE_C_CUC801_0
(PEROXISOMAL COPPER
AMINE OXIDASE)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		3 / 3 HIS A 210
HIS A 179
HIS A  69
 CUO  A9001 (-3.3A)
CUO  A9001 (-3.4A)
CUO  A9001 (-3.1A)
 0.71A 2oqeC-4bedA:
undetectable		 2oqeC-4bedA:
17.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OQE_C_CUC801_0
(PEROXISOMAL COPPER
AMINE OXIDASE)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		3 / 3 HIS A1455
HIS A1424
HIS A1320
 CUO  A9004 (-3.3A)
CUO  A9004 (-3.0A)
CUO  A9004 (-3.5A)
 0.72A 2oqeC-4bedA:
undetectable		 2oqeC-4bedA:
17.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OQE_C_CUC801_0
(PEROXISOMAL COPPER
AMINE OXIDASE)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		3 / 3 HIS B1878
HIS B1847
HIS B1734
 CUO  B9005 (-3.3A)
CUO  B9005 (-3.2A)
CUO  B9005 (-3.4A)
 0.69A 2oqeC-4bedB:
undetectable		 2oqeC-4bedB:
17.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OQE_C_CUC801_0
(PEROXISOMAL COPPER
AMINE OXIDASE)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		3 / 3 HIS B2291
HIS B2260
HIS B2150
 CUO  B9006 (-3.5A)
CUO  B9006 (-3.2A)
CUO  B9006 (-3.3A)
 0.72A 2oqeC-4bedB:
undetectable		 2oqeC-4bedB:
17.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OQE_C_CUC801_0
(PEROXISOMAL COPPER
AMINE OXIDASE)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		3 / 3 HIS B2701
HIS B2670
HIS B2570
 CUO  B9007 (-3.1A)
CUO  B9007 (-3.4A)
CUO  B9007 (-3.3A)
 0.72A 2oqeC-4bedB:
undetectable		 2oqeC-4bedB:
17.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OQE_D_CUD801_0
(PEROXISOMAL COPPER
AMINE OXIDASE)		 1js8 HEMOCYANIN
(Enteroctopus
dofleini) 		3 / 3 HIS A2702
HIS A2671
HIS A2571
 CUO  A 888 (-3.3A)
CUO  A 888 (-3.4A)
CUO  A 888 (-3.3A)
 0.71A 2oqeD-1js8A:
undetectable		 2oqeD-1js8A:
19.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OQE_D_CUD801_0
(PEROXISOMAL COPPER
AMINE OXIDASE)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		3 / 3 HIS A 210
HIS A 179
HIS A  69
 CUO  A9001 (-3.3A)
CUO  A9001 (-3.4A)
CUO  A9001 (-3.1A)
 0.69A 2oqeD-4bedA:
undetectable		 2oqeD-4bedA:
17.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OQE_D_CUD801_0
(PEROXISOMAL COPPER
AMINE OXIDASE)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		3 / 3 HIS A1455
HIS A1424
HIS A1320
 CUO  A9004 (-3.3A)
CUO  A9004 (-3.0A)
CUO  A9004 (-3.5A)
 0.70A 2oqeD-4bedA:
undetectable		 2oqeD-4bedA:
17.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OQE_D_CUD801_0
(PEROXISOMAL COPPER
AMINE OXIDASE)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		3 / 3 HIS B1878
HIS B1847
HIS B1734
 CUO  B9005 (-3.3A)
CUO  B9005 (-3.2A)
CUO  B9005 (-3.4A)
 0.67A 2oqeD-4bedB:
undetectable		 2oqeD-4bedB:
17.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OQE_D_CUD801_0
(PEROXISOMAL COPPER
AMINE OXIDASE)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		3 / 3 HIS B2291
HIS B2260
HIS B2150
 CUO  B9006 (-3.5A)
CUO  B9006 (-3.2A)
CUO  B9006 (-3.3A)
 0.71A 2oqeD-4bedB:
undetectable		 2oqeD-4bedB:
17.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OQE_D_CUD801_0
(PEROXISOMAL COPPER
AMINE OXIDASE)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		3 / 3 HIS B2701
HIS B2670
HIS B2570
 CUO  B9007 (-3.1A)
CUO  B9007 (-3.4A)
CUO  B9007 (-3.3A)
 0.71A 2oqeD-4bedB:
undetectable		 2oqeD-4bedB:
17.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OQE_E_CUE801_0
(PEROXISOMAL COPPER
AMINE OXIDASE)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		4 / 4 LEU A 344
HIS A 209
HIS A 183
HIS A 179
 None
None
CUO  A9001 (-3.4A)
CUO  A9001 (-3.4A)
 1.44A 2oqeE-4bedA:
undetectable		 2oqeE-4bedA:
17.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OQE_E_CUE801_0
(PEROXISOMAL COPPER
AMINE OXIDASE)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		4 / 4 LEU A 344
HIS A 210
HIS A 183
HIS A 179
 None
CUO  A9001 (-3.3A)
CUO  A9001 (-3.4A)
CUO  A9001 (-3.4A)
 1.36A 2oqeE-4bedA:
undetectable		 2oqeE-4bedA:
17.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OQE_E_CUE801_0
(PEROXISOMAL COPPER
AMINE OXIDASE)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		4 / 4 LEU A 763
HIS A 633
HIS A 606
HIS A 602
 None
CUO  A9002 (-3.3A)
CUO  A9002 (-3.3A)
CUO  A9002 (-3.4A)
 1.41A 2oqeE-4bedA:
undetectable		 2oqeE-4bedA:
17.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OQE_E_CUE801_0
(PEROXISOMAL COPPER
AMINE OXIDASE)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		4 / 4 LEU A1589
HIS A1455
HIS A1428
HIS A1424
 None
CUO  A9004 (-3.3A)
CUO  A9004 (-3.4A)
CUO  A9004 (-3.0A)
 1.45A 2oqeE-4bedA:
undetectable		 2oqeE-4bedA:
17.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OQE_E_CUE801_0
(PEROXISOMAL COPPER
AMINE OXIDASE)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		4 / 4 LEU B3109
HIS B3079
HIS B3075
HIS B3105
 None
CUO  B9008 (-3.5A)
CUO  B9008 (-2.8A)
None
 1.36A 2oqeE-4bedB:
undetectable		 2oqeE-4bedB:
17.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OQE_F_CUF801_0
(PEROXISOMAL COPPER
AMINE OXIDASE)		 1js8 HEMOCYANIN
(Enteroctopus
dofleini) 		3 / 3 HIS A2702
HIS A2671
HIS A2571
 CUO  A 888 (-3.3A)
CUO  A 888 (-3.4A)
CUO  A 888 (-3.3A)
 0.69A 2oqeF-1js8A:
undetectable		 2oqeF-1js8A:
19.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OQE_F_CUF801_0
(PEROXISOMAL COPPER
AMINE OXIDASE)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		3 / 3 HIS A 210
HIS A 179
HIS A  69
 CUO  A9001 (-3.3A)
CUO  A9001 (-3.4A)
CUO  A9001 (-3.1A)
 0.72A 2oqeF-4bedA:
undetectable		 2oqeF-4bedA:
17.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OQE_F_CUF801_0
(PEROXISOMAL COPPER
AMINE OXIDASE)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		3 / 3 HIS A1455
HIS A1424
HIS A1320
 CUO  A9004 (-3.3A)
CUO  A9004 (-3.0A)
CUO  A9004 (-3.5A)
 0.72A 2oqeF-4bedA:
undetectable		 2oqeF-4bedA:
17.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OQE_F_CUF801_0
(PEROXISOMAL COPPER
AMINE OXIDASE)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		3 / 3 HIS B1878
HIS B1847
HIS B1734
 CUO  B9005 (-3.3A)
CUO  B9005 (-3.2A)
CUO  B9005 (-3.4A)
 0.69A 2oqeF-4bedB:
undetectable		 2oqeF-4bedB:
17.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OQE_F_CUF801_0
(PEROXISOMAL COPPER
AMINE OXIDASE)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		3 / 3 HIS B2291
HIS B2260
HIS B2150
 CUO  B9006 (-3.5A)
CUO  B9006 (-3.2A)
CUO  B9006 (-3.3A)
 0.73A 2oqeF-4bedB:
undetectable		 2oqeF-4bedB:
17.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OQE_F_CUF801_0
(PEROXISOMAL COPPER
AMINE OXIDASE)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		3 / 3 HIS B2701
HIS B2670
HIS B2570
 CUO  B9007 (-3.1A)
CUO  B9007 (-3.4A)
CUO  B9007 (-3.3A)
 0.72A 2oqeF-4bedB:
undetectable		 2oqeF-4bedB:
17.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OZR_F_HAEF3004_1
(COLLAGENASE 3)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		3 / 3 HIS A1311
HIS A1320
HIS A1293
 CUO  A9004 (-3.4A)
CUO  A9004 (-3.5A)
CUO  A9004 (-3.2A)
 0.48A 2ozrF-4bedA:
undetectable		 2ozrF-4bedA:
8.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PGR_A_DCFA501_1
(ADENOSINE DEAMINASE)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		5 / 12 HIS A 179
HIS A 183
ASP A 203
HIS A 210
HIS A  69
 CUO  A9001 (-3.4A)
CUO  A9001 (-3.4A)
None
CUO  A9001 (-3.3A)
CUO  A9001 (-3.1A)
 0.85A 2pgrA-4bedA:
undetectable		 2pgrA-4bedA:
14.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PGR_A_DCFA501_1
(ADENOSINE DEAMINASE)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		5 / 12 HIS A 602
HIS A 606
ASP A 626
HIS A 633
HIS A 491
 CUO  A9002 (-3.4A)
CUO  A9002 (-3.3A)
None
CUO  A9002 (-3.3A)
CUO  A9002 (-3.4A)
 0.87A 2pgrA-4bedA:
undetectable		 2pgrA-4bedA:
14.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PGR_A_DCFA501_1
(ADENOSINE DEAMINASE)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		5 / 12 HIS A 905
HIS A 876
ASP A1179
GLY A1178
HIS A 896
 CUO  A9003 (-3.5A)
CUO  A9003 (-3.3A)
None
None
CUO  A9003 (-3.4A)
 1.14A 2pgrA-4bedA:
undetectable		 2pgrA-4bedA:
14.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PGR_A_DCFA501_1
(ADENOSINE DEAMINASE)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		5 / 12 HIS B2260
HIS B2264
ASP B2284
HIS B2291
HIS B2150
 CUO  B9006 (-3.2A)
CUO  B9006 (-3.2A)
None
CUO  B9006 (-3.5A)
CUO  B9006 (-3.3A)
 0.91A 2pgrA-4bedB:
undetectable		 2pgrA-4bedB:
12.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PGR_A_DCFA501_1
(ADENOSINE DEAMINASE)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		5 / 12 HIS B2670
HIS B2674
ASP B2694
HIS B2701
HIS B2570
 CUO  B9007 (-3.4A)
CUO  B9007 (-3.4A)
None
CUO  B9007 (-3.1A)
CUO  B9007 (-3.3A)
 0.88A 2pgrA-4bedB:
undetectable		 2pgrA-4bedB:
12.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PGR_A_DCFA501_1
(ADENOSINE DEAMINASE)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		5 / 12 HIS B2974
HIS B2946
GLY B3237
HIS B2965
HIS B3075
 CUO  B9008 (-2.9A)
CUO  B9008 (-3.1A)
None
CUO  B9008 (-3.2A)
CUO  B9008 (-2.8A)
 0.89A 2pgrA-4bedB:
undetectable		 2pgrA-4bedB:
12.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PGR_A_DCFA501_1
(ADENOSINE DEAMINASE)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		5 / 12 HIS B3075
HIS B3079
ASP B3099
HIS B3106
HIS B2974
 CUO  B9008 (-2.8A)
CUO  B9008 (-3.5A)
None
CUO  B9008 (-3.3A)
CUO  B9008 (-2.9A)
 1.03A 2pgrA-4bedB:
undetectable		 2pgrA-4bedB:
12.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W0Q_A_CUA801_0
(COPPER AMINE OXIDASE)		 1js8 HEMOCYANIN
(Enteroctopus
dofleini) 		3 / 3 HIS A2702
HIS A2671
HIS A2571
 CUO  A 888 (-3.3A)
CUO  A 888 (-3.4A)
CUO  A 888 (-3.3A)
 0.68A 2w0qA-1js8A:
undetectable		 2w0qA-1js8A:
20.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W0Q_A_CUA801_0
(COPPER AMINE OXIDASE)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		3 / 3 HIS B1878
HIS B1847
HIS B1734
 CUO  B9005 (-3.3A)
CUO  B9005 (-3.2A)
CUO  B9005 (-3.4A)
 0.70A 2w0qA-4bedB:
undetectable		 2w0qA-4bedB:
18.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W0Q_B_CUB801_0
(COPPER AMINE OXIDASE)		 1js8 HEMOCYANIN
(Enteroctopus
dofleini) 		3 / 3 HIS A2702
HIS A2671
HIS A2571
 CUO  A 888 (-3.3A)
CUO  A 888 (-3.4A)
CUO  A 888 (-3.3A)
 0.69A 2w0qB-1js8A:
undetectable		 2w0qB-1js8A:
20.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W0Q_B_CUB801_0
(COPPER AMINE OXIDASE)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		3 / 3 HIS B1878
HIS B1847
HIS B1734
 CUO  B9005 (-3.3A)
CUO  B9005 (-3.2A)
CUO  B9005 (-3.4A)
 0.68A 2w0qB-4bedB:
undetectable		 2w0qB-4bedB:
18.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W0Q_B_CUB801_0
(COPPER AMINE OXIDASE)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		3 / 3 HIS B2701
HIS B2670
HIS B2570
 CUO  B9007 (-3.1A)
CUO  B9007 (-3.4A)
CUO  B9007 (-3.3A)
 0.70A 2w0qB-4bedB:
undetectable		 2w0qB-4bedB:
18.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WKO_A_CUA154_0
(SUPEROXIDE DISMUTASE
[CU-ZN])		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		4 / 4 HIS B2974
HIS B3075
HIS B3106
HIS B2965
 CUO  B9008 (-2.9A)
CUO  B9008 (-2.8A)
CUO  B9008 (-3.3A)
CUO  B9008 (-3.2A)
 0.83A 2wkoA-4bedB:
undetectable		 2wkoA-4bedB:
6.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WKO_A_CUA154_0
(SUPEROXIDE DISMUTASE
[CU-ZN])		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		4 / 4 HIS B3075
HIS B3106
HIS B2974
HIS B3079
 CUO  B9008 (-2.8A)
CUO  B9008 (-3.3A)
CUO  B9008 (-2.9A)
CUO  B9008 (-3.5A)
 1.01A 2wkoA-4bedB:
undetectable		 2wkoA-4bedB:
6.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WKO_F_CUF154_0
(SUPEROXIDE DISMUTASE
[CU-ZN])		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		4 / 5 HIS A 179
HIS A 183
VAL A 213
HIS A 210
 CUO  A9001 (-3.4A)
CUO  A9001 (-3.4A)
None
CUO  A9001 (-3.3A)
 1.04A 2wkoF-4bedA:
undetectable		 2wkoF-4bedA:
6.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WKO_F_CUF154_0
(SUPEROXIDE DISMUTASE
[CU-ZN])		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		4 / 5 HIS A 602
HIS A 606
VAL A 636
HIS A 633
 CUO  A9002 (-3.4A)
CUO  A9002 (-3.3A)
None
CUO  A9002 (-3.3A)
 1.00A 2wkoF-4bedA:
undetectable		 2wkoF-4bedA:
6.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WKO_F_CUF154_0
(SUPEROXIDE DISMUTASE
[CU-ZN])		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		4 / 5 HIS B2260
HIS B2264
VAL B2294
HIS B2291
 CUO  B9006 (-3.2A)
CUO  B9006 (-3.2A)
None
CUO  B9006 (-3.5A)
 1.03A 2wkoF-4bedB:
undetectable		 2wkoF-4bedB:
6.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WKO_F_CUF154_0
(SUPEROXIDE DISMUTASE
[CU-ZN])		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		4 / 5 HIS B2974
HIS B3075
HIS B3106
HIS B2965
 CUO  B9008 (-2.9A)
CUO  B9008 (-2.8A)
CUO  B9008 (-3.3A)
CUO  B9008 (-3.2A)
 0.83A 2wkoF-4bedB:
undetectable		 2wkoF-4bedB:
6.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y69_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		3 / 3 HIS B2946
HIS B3106
HIS B2974
 CUO  B9008 (-3.1A)
CUO  B9008 (-3.3A)
CUO  B9008 (-2.9A)
 0.74A 2y69A-4bedB:
undetectable		 2y69A-4bedB:
14.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y69_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		3 / 3 HIS B2946
HIS B3106
HIS B2974
 CUO  B9008 (-3.1A)
CUO  B9008 (-3.3A)
CUO  B9008 (-2.9A)
 0.74A 2y69N-4bedB:
undetectable		 2y69N-4bedB:
14.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZLC_A_VDXA500_1
(VITAMIN D3 RECEPTOR)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		5 / 12 VAL B3078
HIS B3075
LEU B3109
HIS B3106
LEU B3236
 None
CUO  B9008 (-2.8A)
None
CUO  B9008 (-3.3A)
None
 1.42A 2zlcA-4bedB:
undetectable		 2zlcA-4bedB:
10.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZWE_B_DAHB98_1
(TYROSINASE
MELC)		 1js8 HEMOCYANIN
(Enteroctopus
dofleini) 		5 / 11 HIS A2543
HIS A2562
HIS A2671
ASN A2672
HIS A2675
 CUO  A 888 (-3.4A)
CUO  A 888 (-3.4A)
CUO  A 888 (-3.4A)
None
CUO  A 888 (-3.3A)
 0.52A 2zweA-1js8A:
23.0
2zweB-1js8A:
0.0		 2zweA-1js8A:
21.95
2zweB-1js8A:
14.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZWE_B_DAHB98_1
(TYROSINASE
MELC)		 3wky PROPHENOLOXIDASE B
(Marsupenaeus
japonicus) 		5 / 11 HIS A 199
HIS A 203
HIS A 357
ASN A 358
HIS A 361
 CUO  A 708 (-3.3A)
CUO  A 708 (-3.5A)
CUO  A 708 (-3.3A)
None
CUO  A 708 (-3.2A)
 0.71A 2zweA-3wkyA:
10.3
2zweB-3wkyA:
undetectable		 2zweA-3wkyA:
18.10
2zweB-3wkyA:
10.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZWE_B_DAHB98_1
(TYROSINASE
MELC)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		5 / 11 HIS A  42
HIS A  69
HIS A 179
ASN A 180
HIS A 183
 CUO  A9001 (-3.4A)
CUO  A9001 (-3.1A)
CUO  A9001 (-3.4A)
None
CUO  A9001 (-3.4A)
 1.49A 2zweA-4bedA:
20.5
2zweB-4bedA:
undetectable		 2zweA-4bedA:
9.93
2zweB-4bedA:
6.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZWE_B_DAHB98_1
(TYROSINASE
MELC)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		5 / 11 HIS A 462
HIS A 482
HIS A 602
ASN A 603
HIS A 606
 CUO  A9002 (-3.2A)
CUO  A9002 (-3.4A)
CUO  A9002 (-3.4A)
None
CUO  A9002 (-3.3A)
 0.95A 2zweA-4bedA:
20.5
2zweB-4bedA:
undetectable		 2zweA-4bedA:
9.93
2zweB-4bedA:
6.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZWE_B_DAHB98_1
(TYROSINASE
MELC)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		5 / 11 HIS A 462
HIS A 491
HIS A 602
ASN A 603
HIS A 606
 CUO  A9002 (-3.2A)
CUO  A9002 (-3.4A)
CUO  A9002 (-3.4A)
None
CUO  A9002 (-3.3A)
 1.49A 2zweA-4bedA:
20.5
2zweB-4bedA:
undetectable		 2zweA-4bedA:
9.93
2zweB-4bedA:
6.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZWE_B_DAHB98_1
(TYROSINASE
MELC)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		5 / 11 HIS A 876
HIS A 896
HIS A1015
ASN A1016
HIS A1019
 CUO  A9003 (-3.3A)
CUO  A9003 (-3.4A)
CUO  A9003 (-3.1A)
None
CUO  A9003 (-3.4A)
 1.00A 2zweA-4bedA:
20.5
2zweB-4bedA:
undetectable		 2zweA-4bedA:
9.93
2zweB-4bedA:
6.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZWE_B_DAHB98_1
(TYROSINASE
MELC)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		5 / 11 HIS B1705
HIS B1725
HIS B1847
ASN B1848
HIS B1851
 CUO  B9005 (-3.2A)
CUO  B9005 (-3.1A)
CUO  B9005 (-3.2A)
None
CUO  B9005 (-3.2A)
 0.82A 2zweA-4bedB:
21.3
2zweB-4bedB:
undetectable		 2zweA-4bedB:
10.39
2zweB-4bedB:
5.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZWE_B_DAHB98_1
(TYROSINASE
MELC)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		5 / 11 HIS B2122
HIS B2141
HIS B2260
ASN B2261
HIS B2264
 CUO  B9006 (-3.2A)
CUO  B9006 (-3.1A)
CUO  B9006 (-3.2A)
None
CUO  B9006 (-3.2A)
 0.88A 2zweA-4bedB:
21.3
2zweB-4bedB:
undetectable		 2zweA-4bedB:
10.39
2zweB-4bedB:
5.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZWE_B_DAHB98_1
(TYROSINASE
MELC)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		5 / 11 HIS B2542
HIS B2561
HIS B2670
ASN B2671
HIS B2674
 CUO  B9007 (-3.3A)
CUO  B9007 (-3.3A)
CUO  B9007 (-3.4A)
None
CUO  B9007 (-3.4A)
 0.90A 2zweA-4bedB:
21.3
2zweB-4bedB:
undetectable		 2zweA-4bedB:
10.39
2zweB-4bedB:
5.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZWE_B_DAHB98_1
(TYROSINASE
MELC)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		5 / 11 HIS B2946
HIS B2965
HIS B3075
HIS B3079
SER B3096
 CUO  B9008 (-3.1A)
CUO  B9008 (-3.2A)
CUO  B9008 (-2.8A)
CUO  B9008 (-3.5A)
CUO  B9008 ( 4.7A)
 0.71A 2zweA-4bedB:
21.3
2zweB-4bedB:
undetectable		 2zweA-4bedB:
10.39
2zweB-4bedB:
5.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZWE_B_DAHB98_1
(TYROSINASE
MELC)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		5 / 11 HIS B2946
HIS B3075
ASN B3076
HIS B3079
SER B3096
 CUO  B9008 (-3.1A)
CUO  B9008 (-2.8A)
None
CUO  B9008 (-3.5A)
CUO  B9008 ( 4.7A)
 0.48A 2zweA-4bedB:
21.3
2zweB-4bedB:
undetectable		 2zweA-4bedB:
10.39
2zweB-4bedB:
5.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZWF_B_DAHB98_1
(TYROSINASE
MELC)		 1js8 HEMOCYANIN
(Enteroctopus
dofleini) 		5 / 11 HIS A2543
HIS A2562
HIS A2671
ASN A2672
HIS A2675
 CUO  A 888 (-3.4A)
CUO  A 888 (-3.4A)
CUO  A 888 (-3.4A)
None
CUO  A 888 (-3.3A)
 0.51A 2zwfA-1js8A:
23.1
2zwfB-1js8A:
0.0		 2zwfA-1js8A:
21.95
2zwfB-1js8A:
14.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZWF_B_DAHB98_1
(TYROSINASE
MELC)		 1js8 HEMOCYANIN
(Enteroctopus
dofleini) 		5 / 11 HIS A2543
HIS A2571
HIS A2671
ASN A2672
HIS A2675
 CUO  A 888 (-3.4A)
CUO  A 888 (-3.3A)
CUO  A 888 (-3.4A)
None
CUO  A 888 (-3.3A)
 1.46A 2zwfA-1js8A:
23.1
2zwfB-1js8A:
0.0		 2zwfA-1js8A:
21.95
2zwfB-1js8A:
14.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZWF_B_DAHB98_1
(TYROSINASE
MELC)		 3wky PROPHENOLOXIDASE B
(Marsupenaeus
japonicus) 		5 / 11 HIS A 199
HIS A 203
HIS A 357
ASN A 358
HIS A 361
 CUO  A 708 (-3.3A)
CUO  A 708 (-3.5A)
CUO  A 708 (-3.3A)
None
CUO  A 708 (-3.2A)
 0.74A 2zwfA-3wkyA:
10.3
2zwfB-3wkyA:
undetectable		 2zwfA-3wkyA:
18.10
2zwfB-3wkyA:
10.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZWF_B_DAHB98_1
(TYROSINASE
MELC)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		5 / 11 HIS A  42
HIS A  69
HIS A 179
ASN A 180
HIS A 183
 CUO  A9001 (-3.4A)
CUO  A9001 (-3.1A)
CUO  A9001 (-3.4A)
None
CUO  A9001 (-3.4A)
 1.43A 2zwfA-4bedA:
20.6
2zwfB-4bedA:
undetectable		 2zwfA-4bedA:
9.93
2zwfB-4bedA:
6.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZWF_B_DAHB98_1
(TYROSINASE
MELC)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		5 / 11 HIS A 462
HIS A 482
HIS A 602
ASN A 603
HIS A 606
 CUO  A9002 (-3.2A)
CUO  A9002 (-3.4A)
CUO  A9002 (-3.4A)
None
CUO  A9002 (-3.3A)
 0.99A 2zwfA-4bedA:
20.6
2zwfB-4bedA:
undetectable		 2zwfA-4bedA:
9.93
2zwfB-4bedA:
6.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZWF_B_DAHB98_1
(TYROSINASE
MELC)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		5 / 11 HIS A 462
HIS A 491
HIS A 602
ASN A 603
HIS A 606
 CUO  A9002 (-3.2A)
CUO  A9002 (-3.4A)
CUO  A9002 (-3.4A)
None
CUO  A9002 (-3.3A)
 1.42A 2zwfA-4bedA:
20.6
2zwfB-4bedA:
undetectable		 2zwfA-4bedA:
9.93
2zwfB-4bedA:
6.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZWF_B_DAHB98_1
(TYROSINASE
MELC)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		5 / 11 HIS A 876
HIS A 896
HIS A1015
ASN A1016
HIS A1019
 CUO  A9003 (-3.3A)
CUO  A9003 (-3.4A)
CUO  A9003 (-3.1A)
None
CUO  A9003 (-3.4A)
 1.03A 2zwfA-4bedA:
20.6
2zwfB-4bedA:
undetectable		 2zwfA-4bedA:
9.93
2zwfB-4bedA:
6.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZWF_B_DAHB98_1
(TYROSINASE
MELC)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		5 / 11 HIS A 876
HIS A 905
HIS A1015
ASN A1016
HIS A1019
 CUO  A9003 (-3.3A)
CUO  A9003 (-3.5A)
CUO  A9003 (-3.1A)
None
CUO  A9003 (-3.4A)
 1.48A 2zwfA-4bedA:
20.6
2zwfB-4bedA:
undetectable		 2zwfA-4bedA:
9.93
2zwfB-4bedA:
6.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZWF_B_DAHB98_1
(TYROSINASE
MELC)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		5 / 11 HIS B1705
HIS B1725
HIS B1847
ASN B1848
HIS B1851
 CUO  B9005 (-3.2A)
CUO  B9005 (-3.1A)
CUO  B9005 (-3.2A)
None
CUO  B9005 (-3.2A)
 0.82A 2zwfA-4bedB:
21.3
2zwfB-4bedB:
undetectable		 2zwfA-4bedB:
10.39
2zwfB-4bedB:
5.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZWF_B_DAHB98_1
(TYROSINASE
MELC)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		5 / 11 HIS B1705
HIS B1734
HIS B1847
ASN B1848
HIS B1851
 CUO  B9005 (-3.2A)
CUO  B9005 (-3.4A)
CUO  B9005 (-3.2A)
None
CUO  B9005 (-3.2A)
 1.49A 2zwfA-4bedB:
21.3
2zwfB-4bedB:
undetectable		 2zwfA-4bedB:
10.39
2zwfB-4bedB:
5.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZWF_B_DAHB98_1
(TYROSINASE
MELC)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		5 / 11 HIS B2122
HIS B2141
HIS B2260
ASN B2261
HIS B2264
 CUO  B9006 (-3.2A)
CUO  B9006 (-3.1A)
CUO  B9006 (-3.2A)
None
CUO  B9006 (-3.2A)
 0.91A 2zwfA-4bedB:
21.3
2zwfB-4bedB:
undetectable		 2zwfA-4bedB:
10.39
2zwfB-4bedB:
5.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZWF_B_DAHB98_1
(TYROSINASE
MELC)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		5 / 11 HIS B2542
HIS B2561
HIS B2670
ASN B2671
HIS B2674
 CUO  B9007 (-3.3A)
CUO  B9007 (-3.3A)
CUO  B9007 (-3.4A)
None
CUO  B9007 (-3.4A)
 0.90A 2zwfA-4bedB:
21.3
2zwfB-4bedB:
undetectable		 2zwfA-4bedB:
10.39
2zwfB-4bedB:
5.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZWF_B_DAHB98_1
(TYROSINASE
MELC)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		5 / 11 HIS B2946
HIS B2965
HIS B3075
HIS B3079
SER B3096
 CUO  B9008 (-3.1A)
CUO  B9008 (-3.2A)
CUO  B9008 (-2.8A)
CUO  B9008 (-3.5A)
CUO  B9008 ( 4.7A)
 0.73A 2zwfA-4bedB:
21.3
2zwfB-4bedB:
undetectable		 2zwfA-4bedB:
10.39
2zwfB-4bedB:
5.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZWF_B_DAHB98_1
(TYROSINASE
MELC)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		5 / 11 HIS B2946
HIS B2974
ASN B3076
HIS B3079
SER B3096
 CUO  B9008 (-3.1A)
CUO  B9008 (-2.9A)
None
CUO  B9008 (-3.5A)
CUO  B9008 ( 4.7A)
 1.45A 2zwfA-4bedB:
21.3
2zwfB-4bedB:
undetectable		 2zwfA-4bedB:
10.39
2zwfB-4bedB:
5.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZWF_B_DAHB98_1
(TYROSINASE
MELC)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		5 / 11 HIS B2946
HIS B3075
ASN B3076
HIS B3079
SER B3096
 CUO  B9008 (-3.1A)
CUO  B9008 (-2.8A)
None
CUO  B9008 (-3.5A)
CUO  B9008 ( 4.7A)
 0.43A 2zwfA-4bedB:
21.3
2zwfB-4bedB:
undetectable		 2zwfA-4bedB:
10.39
2zwfB-4bedB:
5.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZWG_B_DAHB98_1
(TYROSINASE
MELC)		 1js8 HEMOCYANIN
(Enteroctopus
dofleini) 		5 / 11 HIS A2543
HIS A2562
HIS A2671
ASN A2672
HIS A2675
 CUO  A 888 (-3.4A)
CUO  A 888 (-3.4A)
CUO  A 888 (-3.4A)
None
CUO  A 888 (-3.3A)
 0.50A 2zwgA-1js8A:
23.1
2zwgB-1js8A:
0.0		 2zwgA-1js8A:
21.95
2zwgB-1js8A:
14.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZWG_B_DAHB98_1
(TYROSINASE
MELC)		 1js8 HEMOCYANIN
(Enteroctopus
dofleini) 		5 / 11 HIS A2543
HIS A2571
HIS A2671
ASN A2672
HIS A2675
 CUO  A 888 (-3.4A)
CUO  A 888 (-3.3A)
CUO  A 888 (-3.4A)
None
CUO  A 888 (-3.3A)
 1.43A 2zwgA-1js8A:
23.1
2zwgB-1js8A:
0.0		 2zwgA-1js8A:
21.95
2zwgB-1js8A:
14.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZWG_B_DAHB98_1
(TYROSINASE
MELC)		 3wky PROPHENOLOXIDASE B
(Marsupenaeus
japonicus) 		5 / 11 HIS A 199
HIS A 203
HIS A 357
ASN A 358
HIS A 361
 CUO  A 708 (-3.3A)
CUO  A 708 (-3.5A)
CUO  A 708 (-3.3A)
None
CUO  A 708 (-3.2A)
 0.73A 2zwgA-3wkyA:
10.5
2zwgB-3wkyA:
undetectable		 2zwgA-3wkyA:
18.10
2zwgB-3wkyA:
10.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZWG_B_DAHB98_1
(TYROSINASE
MELC)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		5 / 11 HIS A  42
HIS A  60
HIS A 179
ASN A 180
HIS A 183
 CUO  A9001 (-3.4A)
CUO  A9001 (-3.1A)
CUO  A9001 (-3.4A)
None
CUO  A9001 (-3.4A)
 1.00A 2zwgA-4bedA:
20.5
2zwgB-4bedA:
undetectable		 2zwgA-4bedA:
9.93
2zwgB-4bedA:
6.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZWG_B_DAHB98_1
(TYROSINASE
MELC)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		5 / 11 HIS A  42
HIS A  69
HIS A 179
ASN A 180
HIS A 183
 CUO  A9001 (-3.4A)
CUO  A9001 (-3.1A)
CUO  A9001 (-3.4A)
None
CUO  A9001 (-3.4A)
 1.40A 2zwgA-4bedA:
20.5
2zwgB-4bedA:
undetectable		 2zwgA-4bedA:
9.93
2zwgB-4bedA:
6.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZWG_B_DAHB98_1
(TYROSINASE
MELC)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		5 / 11 HIS A 462
HIS A 482
HIS A 602
ASN A 603
HIS A 606
 CUO  A9002 (-3.2A)
CUO  A9002 (-3.4A)
CUO  A9002 (-3.4A)
None
CUO  A9002 (-3.3A)
 0.98A 2zwgA-4bedA:
20.5
2zwgB-4bedA:
undetectable		 2zwgA-4bedA:
9.93
2zwgB-4bedA:
6.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZWG_B_DAHB98_1
(TYROSINASE
MELC)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		5 / 11 HIS A 462
HIS A 491
HIS A 602
ASN A 603
HIS A 606
 CUO  A9002 (-3.2A)
CUO  A9002 (-3.4A)
CUO  A9002 (-3.4A)
None
CUO  A9002 (-3.3A)
 1.39A 2zwgA-4bedA:
20.5
2zwgB-4bedA:
undetectable		 2zwgA-4bedA:
9.93
2zwgB-4bedA:
6.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZWG_B_DAHB98_1
(TYROSINASE
MELC)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		5 / 11 HIS A 876
HIS A 896
HIS A1015
ASN A1016
HIS A1019
 CUO  A9003 (-3.3A)
CUO  A9003 (-3.4A)
CUO  A9003 (-3.1A)
None
CUO  A9003 (-3.4A)
 1.03A 2zwgA-4bedA:
20.5
2zwgB-4bedA:
undetectable		 2zwgA-4bedA:
9.93
2zwgB-4bedA:
6.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZWG_B_DAHB98_1
(TYROSINASE
MELC)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		5 / 11 HIS A 876
HIS A 905
HIS A1015
ASN A1016
HIS A1019
 CUO  A9003 (-3.3A)
CUO  A9003 (-3.5A)
CUO  A9003 (-3.1A)
None
CUO  A9003 (-3.4A)
 1.45A 2zwgA-4bedA:
20.5
2zwgB-4bedA:
undetectable		 2zwgA-4bedA:
9.93
2zwgB-4bedA:
6.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZWG_B_DAHB98_1
(TYROSINASE
MELC)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		5 / 11 HIS B1705
HIS B1725
HIS B1847
ASN B1848
HIS B1851
 CUO  B9005 (-3.2A)
CUO  B9005 (-3.1A)
CUO  B9005 (-3.2A)
None
CUO  B9005 (-3.2A)
 0.81A 2zwgA-4bedB:
23.1
2zwgB-4bedB:
undetectable		 2zwgA-4bedB:
10.39
2zwgB-4bedB:
5.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZWG_B_DAHB98_1
(TYROSINASE
MELC)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		5 / 11 HIS B1705
HIS B1734
HIS B1847
ASN B1848
HIS B1851
 CUO  B9005 (-3.2A)
CUO  B9005 (-3.4A)
CUO  B9005 (-3.2A)
None
CUO  B9005 (-3.2A)
 1.46A 2zwgA-4bedB:
23.1
2zwgB-4bedB:
undetectable		 2zwgA-4bedB:
10.39
2zwgB-4bedB:
5.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZWG_B_DAHB98_1
(TYROSINASE
MELC)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		5 / 11 HIS B2122
HIS B2141
HIS B2260
ASN B2261
HIS B2264
 CUO  B9006 (-3.2A)
CUO  B9006 (-3.1A)
CUO  B9006 (-3.2A)
None
CUO  B9006 (-3.2A)
 0.91A 2zwgA-4bedB:
23.1
2zwgB-4bedB:
undetectable		 2zwgA-4bedB:
10.39
2zwgB-4bedB:
5.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZWG_B_DAHB98_1
(TYROSINASE
MELC)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		5 / 11 HIS B2122
HIS B2150
HIS B2260
ASN B2261
HIS B2264
 CUO  B9006 (-3.2A)
CUO  B9006 (-3.3A)
CUO  B9006 (-3.2A)
None
CUO  B9006 (-3.2A)
 1.46A 2zwgA-4bedB:
23.1
2zwgB-4bedB:
undetectable		 2zwgA-4bedB:
10.39
2zwgB-4bedB:
5.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZWG_B_DAHB98_1
(TYROSINASE
MELC)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		5 / 11 HIS B2542
HIS B2561
HIS B2670
ASN B2671
HIS B2674
 CUO  B9007 (-3.3A)
CUO  B9007 (-3.3A)
CUO  B9007 (-3.4A)
None
CUO  B9007 (-3.4A)
 0.88A 2zwgA-4bedB:
23.1
2zwgB-4bedB:
undetectable		 2zwgA-4bedB:
10.39
2zwgB-4bedB:
5.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZWG_B_DAHB98_1
(TYROSINASE
MELC)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		5 / 11 HIS B2542
HIS B2570
HIS B2670
ASN B2671
HIS B2674
 CUO  B9007 (-3.3A)
CUO  B9007 (-3.3A)
CUO  B9007 (-3.4A)
None
CUO  B9007 (-3.4A)
 1.47A 2zwgA-4bedB:
23.1
2zwgB-4bedB:
undetectable		 2zwgA-4bedB:
10.39
2zwgB-4bedB:
5.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZWG_B_DAHB98_1
(TYROSINASE
MELC)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		5 / 11 HIS B2946
HIS B2965
HIS B3075
HIS B3079
SER B3096
 CUO  B9008 (-3.1A)
CUO  B9008 (-3.2A)
CUO  B9008 (-2.8A)
CUO  B9008 (-3.5A)
CUO  B9008 ( 4.7A)
 0.70A 2zwgA-4bedB:
23.1
2zwgB-4bedB:
undetectable		 2zwgA-4bedB:
10.39
2zwgB-4bedB:
5.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZWG_B_DAHB98_1
(TYROSINASE
MELC)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		6 / 11 HIS B2946
HIS B2974
HIS B3075
ASN B3076
HIS B3079
SER B3096
 CUO  B9008 (-3.1A)
CUO  B9008 (-2.9A)
CUO  B9008 (-2.8A)
None
CUO  B9008 (-3.5A)
CUO  B9008 ( 4.7A)
 1.39A 2zwgA-4bedB:
23.1
2zwgB-4bedB:
undetectable		 2zwgA-4bedB:
10.39
2zwgB-4bedB:
5.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZWG_B_DAHB98_1
(TYROSINASE
MELC)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		5 / 11 HIS B3079
HIS B3075
HIS B2974
HIS B2946
SER B3096
 CUO  B9008 (-3.5A)
CUO  B9008 (-2.8A)
CUO  B9008 (-2.9A)
CUO  B9008 (-3.1A)
CUO  B9008 ( 4.7A)
 1.44A 2zwgA-4bedB:
23.1
2zwgB-4bedB:
undetectable		 2zwgA-4bedB:
10.39
2zwgB-4bedB:
5.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZXW_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		3 / 3 HIS B2946
HIS B3106
HIS B2974
 CUO  B9008 (-3.1A)
CUO  B9008 (-3.3A)
CUO  B9008 (-2.9A)
 0.75A 2zxwN-4bedB:
undetectable		 2zxwN-4bedB:
14.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABK_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		3 / 3 HIS B2946
HIS B3106
HIS B2974
 CUO  B9008 (-3.1A)
CUO  B9008 (-3.3A)
CUO  B9008 (-2.9A)
 0.72A 3abkA-4bedB:
undetectable		 3abkA-4bedB:
14.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABL_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		4 / 8 HIS A 482
ASP A 626
THR A 623
TYR A 622
 CUO  A9002 (-3.4A)
None
CUO  A9002 ( 4.5A)
None
 1.15A 3ablA-4bedA:
undetectable
3ablC-4bedA:
undetectable
3ablP-4bedA:
undetectable		 3ablA-4bedA:
14.65
3ablC-4bedA:
9.60
3ablP-4bedA:
9.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABM_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		3 / 3 HIS B2946
HIS B3106
HIS B2974
 CUO  B9008 (-3.1A)
CUO  B9008 (-3.3A)
CUO  B9008 (-2.9A)
 0.72A 3abmA-4bedB:
undetectable		 3abmA-4bedB:
14.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABM_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		3 / 3 HIS B2946
HIS B3106
HIS B2974
 CUO  B9008 (-3.1A)
CUO  B9008 (-3.3A)
CUO  B9008 (-2.9A)
 0.74A 3abmN-4bedB:
undetectable		 3abmN-4bedB:
14.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG1_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		3 / 3 HIS B2946
HIS B3106
HIS B2974
 CUO  B9008 (-3.1A)
CUO  B9008 (-3.3A)
CUO  B9008 (-2.9A)
 0.65A 3ag1A-4bedB:
undetectable		 3ag1A-4bedB:
14.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG1_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		3 / 3 HIS B3106
HIS B3079
HIS B3075
 CUO  B9008 (-3.3A)
CUO  B9008 (-3.5A)
CUO  B9008 (-2.8A)
 0.74A 3ag1A-4bedB:
undetectable		 3ag1A-4bedB:
14.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG1_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		3 / 3 HIS B2946
HIS B3106
HIS B2974
 CUO  B9008 (-3.1A)
CUO  B9008 (-3.3A)
CUO  B9008 (-2.9A)
 0.68A 3ag1N-4bedB:
1.1		 3ag1N-4bedB:
14.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG1_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		3 / 3 HIS B3106
HIS B3079
HIS B3075
 CUO  B9008 (-3.3A)
CUO  B9008 (-3.5A)
CUO  B9008 (-2.8A)
 0.75A 3ag1N-4bedB:
1.1		 3ag1N-4bedB:
14.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG2_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1js8 HEMOCYANIN
(Enteroctopus
dofleini) 		3 / 3 HIS A2671
HIS A2702
HIS A2701
 CUO  A 888 (-3.4A)
CUO  A 888 (-3.3A)
None
 0.73A 3ag2A-1js8A:
0.5		 3ag2A-1js8A:
21.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG2_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		3 / 3 HIS B2946
HIS B3106
HIS B2974
 CUO  B9008 (-3.1A)
CUO  B9008 (-3.3A)
CUO  B9008 (-2.9A)
 0.73A 3ag2A-4bedB:
undetectable		 3ag2A-4bedB:
14.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG2_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		3 / 3 HIS B2946
HIS B3106
HIS B2974
 CUO  B9008 (-3.1A)
CUO  B9008 (-3.3A)
CUO  B9008 (-2.9A)
 0.73A 3ag2N-4bedB:
undetectable		 3ag2N-4bedB:
14.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG3_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		3 / 3 HIS B2946
HIS B3106
HIS B2974
 CUO  B9008 (-3.1A)
CUO  B9008 (-3.3A)
CUO  B9008 (-2.9A)
 0.69A 3ag3A-4bedB:
undetectable		 3ag3A-4bedB:
14.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG3_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		3 / 3 HIS B2946
HIS B3106
HIS B2974
 CUO  B9008 (-3.1A)
CUO  B9008 (-3.3A)
CUO  B9008 (-2.9A)
 0.71A 3ag3N-4bedB:
undetectable		 3ag3N-4bedB:
14.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG4_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		3 / 3 HIS A 462
HIS A 633
HIS A 491
 CUO  A9002 (-3.2A)
CUO  A9002 (-3.3A)
CUO  A9002 (-3.4A)
 0.70A 3ag4A-4bedA:
undetectable		 3ag4A-4bedA:
14.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG4_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		3 / 3 HIS A 876
HIS A1046
HIS A 905
 CUO  A9003 (-3.3A)
CUO  A9003 (-3.2A)
CUO  A9003 (-3.5A)
 0.72A 3ag4A-4bedA:
undetectable		 3ag4A-4bedA:
14.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG4_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		3 / 3 HIS A1293
HIS A1455
HIS A1320
 CUO  A9004 (-3.2A)
CUO  A9004 (-3.3A)
CUO  A9004 (-3.5A)
 0.75A 3ag4A-4bedA:
undetectable		 3ag4A-4bedA:
14.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG4_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		3 / 3 HIS B2542
HIS B2701
HIS B2570
 CUO  B9007 (-3.3A)
CUO  B9007 (-3.1A)
CUO  B9007 (-3.3A)
 0.71A 3ag4A-4bedB:
undetectable		 3ag4A-4bedB:
14.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG4_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		3 / 3 HIS B2946
HIS B3106
HIS B2974
 CUO  B9008 (-3.1A)
CUO  B9008 (-3.3A)
CUO  B9008 (-2.9A)
 0.56A 3ag4A-4bedB:
undetectable		 3ag4A-4bedB:
14.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG4_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		3 / 3 HIS B3106
HIS B3079
HIS B3075
 CUO  B9008 (-3.3A)
CUO  B9008 (-3.5A)
CUO  B9008 (-2.8A)
 0.70A 3ag4A-4bedB:
undetectable		 3ag4A-4bedB:
14.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG4_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		3 / 3 HIS A 462
HIS A 633
HIS A 491
 CUO  A9002 (-3.2A)
CUO  A9002 (-3.3A)
CUO  A9002 (-3.4A)
 0.75A 3ag4N-4bedA:
undetectable		 3ag4N-4bedA:
14.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG4_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		3 / 3 HIS A 876
HIS A1046
HIS A 905
 CUO  A9003 (-3.3A)
CUO  A9003 (-3.2A)
CUO  A9003 (-3.5A)
 0.76A 3ag4N-4bedA:
undetectable		 3ag4N-4bedA:
14.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG4_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		3 / 3 HIS B2542
HIS B2701
HIS B2570
 CUO  B9007 (-3.3A)
CUO  B9007 (-3.1A)
CUO  B9007 (-3.3A)
 0.75A 3ag4N-4bedB:
undetectable		 3ag4N-4bedB:
14.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG4_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		3 / 3 HIS B2946
HIS B3106
HIS B2974
 CUO  B9008 (-3.1A)
CUO  B9008 (-3.3A)
CUO  B9008 (-2.9A)
 0.57A 3ag4N-4bedB:
undetectable		 3ag4N-4bedB:
14.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG4_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		3 / 3 HIS B3106
HIS B3079
HIS B3075
 CUO  B9008 (-3.3A)
CUO  B9008 (-3.5A)
CUO  B9008 (-2.8A)
 0.72A 3ag4N-4bedB:
undetectable		 3ag4N-4bedB:
14.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASN_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		3 / 3 HIS B2946
HIS B3106
HIS B2974
 CUO  B9008 (-3.1A)
CUO  B9008 (-3.3A)
CUO  B9008 (-2.9A)
 0.69A 3asnA-4bedB:
undetectable		 3asnA-4bedB:
14.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASN_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		3 / 3 HIS B2946
HIS B3106
HIS B2974
 CUO  B9008 (-3.1A)
CUO  B9008 (-3.3A)
CUO  B9008 (-2.9A)
 0.74A 3asnN-4bedB:
undetectable		 3asnN-4bedB:
14.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASO_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		3 / 3 HIS B2946
HIS B3106
HIS B2974
 CUO  B9008 (-3.1A)
CUO  B9008 (-3.3A)
CUO  B9008 (-2.9A)
 0.68A 3asoA-4bedB:
undetectable		 3asoA-4bedB:
14.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASO_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		3 / 3 HIS B2946
HIS B3106
HIS B2974
 CUO  B9008 (-3.1A)
CUO  B9008 (-3.3A)
CUO  B9008 (-2.9A)
 0.73A 3asoN-4bedB:
undetectable		 3asoN-4bedB:
14.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DTU_A_CUA1023_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1js8 HEMOCYANIN
(Enteroctopus
dofleini) 		3 / 3 HIS A2671
HIS A2702
HIS A2701
 CUO  A 888 (-3.4A)
CUO  A 888 (-3.3A)
None
 0.73A 3dtuA-1js8A:
0.0		 3dtuA-1js8A:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DTU_A_CUA1023_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		3 / 3 HIS B2946
HIS B3106
HIS B2974
 CUO  B9008 (-3.1A)
CUO  B9008 (-3.3A)
CUO  B9008 (-2.9A)
 0.68A 3dtuA-4bedB:
undetectable		 3dtuA-4bedB:
15.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DTU_C_CUC569_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1js8 HEMOCYANIN
(Enteroctopus
dofleini) 		3 / 3 HIS A2671
HIS A2702
HIS A2701
 CUO  A 888 (-3.4A)
CUO  A 888 (-3.3A)
None
 0.74A 3dtuC-1js8A:
0.0		 3dtuC-1js8A:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DTU_C_CUC569_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		3 / 3 HIS B2946
HIS B3106
HIS B2974
 CUO  B9008 (-3.1A)
CUO  B9008 (-3.3A)
CUO  B9008 (-2.9A)
 0.67A 3dtuC-4bedB:
undetectable		 3dtuC-4bedB:
15.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HII_A_CUA801_0
(AMILORIDE-SENSITIVE
AMINE OXIDASE)		 1js8 HEMOCYANIN
(Enteroctopus
dofleini) 		3 / 3 HIS A2702
HIS A2671
HIS A2571
 CUO  A 888 (-3.3A)
CUO  A 888 (-3.4A)
CUO  A 888 (-3.3A)
 0.70A 3hiiA-1js8A:
undetectable		 3hiiA-1js8A:
18.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HII_B_CUB801_0
(AMILORIDE-SENSITIVE
AMINE OXIDASE)		 1js8 HEMOCYANIN
(Enteroctopus
dofleini) 		3 / 3 HIS A2702
HIS A2671
HIS A2571
 CUO  A 888 (-3.3A)
CUO  A 888 (-3.4A)
CUO  A 888 (-3.3A)
 0.70A 3hiiB-1js8A:
undetectable		 3hiiB-1js8A:
18.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LIK_A_HAEA302_1
(MACROPHAGE
METALLOELASTASE)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		4 / 5 HIS A 209
HIS A  60
HIS A  69
HIS A  42
 None
CUO  A9001 (-3.1A)
CUO  A9001 (-3.1A)
CUO  A9001 (-3.4A)
 1.12A 3likA-4bedA:
undetectable		 3likA-4bedA:
6.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LIK_A_HAEA302_1
(MACROPHAGE
METALLOELASTASE)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		4 / 5 HIS B1877
HIS B1725
HIS B1734
HIS B1705
 None
CUO  B9005 (-3.1A)
CUO  B9005 (-3.4A)
CUO  B9005 (-3.2A)
 1.05A 3likA-4bedB:
undetectable		 3likA-4bedB:
6.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LIK_A_HAEA302_1
(MACROPHAGE
METALLOELASTASE)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		4 / 5 HIS B2700
HIS B2561
HIS B2570
HIS B2542
 None
CUO  B9007 (-3.3A)
CUO  B9007 (-3.3A)
CUO  B9007 (-3.3A)
 1.12A 3likA-4bedB:
undetectable		 3likA-4bedB:
6.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LKA_A_HAEA269_1
(MACROPHAGE
METALLOELASTASE)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		4 / 5 HIS A 209
HIS A  60
HIS A  69
HIS A  42
 None
CUO  A9001 (-3.1A)
CUO  A9001 (-3.1A)
CUO  A9001 (-3.4A)
 1.12A 3lkaA-4bedA:
undetectable		 3lkaA-4bedA:
6.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LKA_A_HAEA269_1
(MACROPHAGE
METALLOELASTASE)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		4 / 5 HIS A 632
HIS A 482
HIS A 491
HIS A 462
 None
CUO  A9002 (-3.4A)
CUO  A9002 (-3.4A)
CUO  A9002 (-3.2A)
 1.07A 3lkaA-4bedA:
undetectable		 3lkaA-4bedA:
6.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LKA_A_HAEA269_1
(MACROPHAGE
METALLOELASTASE)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		4 / 5 HIS B1877
HIS B1725
HIS B1734
HIS B1705
 None
CUO  B9005 (-3.1A)
CUO  B9005 (-3.4A)
CUO  B9005 (-3.2A)
 1.03A 3lkaA-4bedB:
undetectable		 3lkaA-4bedB:
7.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LKA_A_HAEA269_1
(MACROPHAGE
METALLOELASTASE)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		4 / 5 HIS B2700
HIS B2561
HIS B2570
HIS B2542
 None
CUO  B9007 (-3.3A)
CUO  B9007 (-3.3A)
CUO  B9007 (-3.3A)
 1.11A 3lkaA-4bedB:
undetectable		 3lkaA-4bedB:
7.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N58_C_ADNC500_2
(ADENOSYLHOMOCYSTEINA
SE)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		4 / 5 LEU B3236
THR B3212
GLU B3072
HIS B3106
 None
None
None
CUO  B9008 (-3.3A)
 1.49A 3n58C-4bedB:
undetectable		 3n58C-4bedB:
14.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NJZ_A_SALA370_1
(GENTISATE
1,2-DIOXYGENASE)		 1js8 HEMOCYANIN
(Enteroctopus
dofleini) 		5 / 12 HIS A2675
HIS A2671
HIS A2702
HIS A2543
ILE A2669
 CUO  A 888 (-3.3A)
CUO  A 888 (-3.4A)
CUO  A 888 (-3.3A)
CUO  A 888 (-3.4A)
None
 1.49A 3njzA-1js8A:
0.0		 3njzA-1js8A:
21.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QPK_A_CUA602_0
(LACCASE-1)		 1js8 HEMOCYANIN
(Enteroctopus
dofleini) 		3 / 3 HIS A2562
HIS A2571
HIS A2543
 CUO  A 888 (-3.4A)
CUO  A 888 (-3.3A)
CUO  A 888 (-3.4A)
 0.36A 3qpkA-1js8A:
undetectable		 3qpkA-1js8A:
18.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QPK_A_CUA602_0
(LACCASE-1)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		3 / 3 HIS A  60
HIS A  69
HIS A  42
 CUO  A9001 (-3.1A)
CUO  A9001 (-3.1A)
CUO  A9001 (-3.4A)
 0.30A 3qpkA-4bedA:
undetectable		 3qpkA-4bedA:
15.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QPK_A_CUA602_0
(LACCASE-1)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		3 / 3 HIS A 482
HIS A 491
HIS A 462
 CUO  A9002 (-3.4A)
CUO  A9002 (-3.4A)
CUO  A9002 (-3.2A)
 0.26A 3qpkA-4bedA:
undetectable		 3qpkA-4bedA:
15.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QPK_A_CUA602_0
(LACCASE-1)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		3 / 3 HIS A 896
HIS A 905
HIS A 876
 CUO  A9003 (-3.4A)
CUO  A9003 (-3.5A)
CUO  A9003 (-3.3A)
 0.27A 3qpkA-4bedA:
undetectable		 3qpkA-4bedA:
15.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QPK_A_CUA602_0
(LACCASE-1)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		3 / 3 HIS A1311
HIS A1320
HIS A1293
 CUO  A9004 (-3.4A)
CUO  A9004 (-3.5A)
CUO  A9004 (-3.2A)
 0.29A 3qpkA-4bedA:
undetectable		 3qpkA-4bedA:
15.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QPK_A_CUA602_0
(LACCASE-1)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		3 / 3 HIS B1725
HIS B1734
HIS B1705
 CUO  B9005 (-3.1A)
CUO  B9005 (-3.4A)
CUO  B9005 (-3.2A)
 0.36A 3qpkA-4bedB:
3.8		 3qpkA-4bedB:
15.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QPK_A_CUA602_0
(LACCASE-1)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		3 / 3 HIS B2141
HIS B2150
HIS B2122
 CUO  B9006 (-3.1A)
CUO  B9006 (-3.3A)
CUO  B9006 (-3.2A)
 0.35A 3qpkA-4bedB:
3.8		 3qpkA-4bedB:
15.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QPK_A_CUA602_0
(LACCASE-1)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		3 / 3 HIS B2561
HIS B2570
HIS B2542
 CUO  B9007 (-3.3A)
CUO  B9007 (-3.3A)
CUO  B9007 (-3.3A)
 0.36A 3qpkA-4bedB:
3.8		 3qpkA-4bedB:
15.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QPK_A_CUA604_0
(LACCASE-1)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		4 / 4 HIS A 179
HIS A  69
HIS A 210
HIS A 209
 CUO  A9001 (-3.4A)
CUO  A9001 (-3.1A)
CUO  A9001 (-3.3A)
None
 1.34A 3qpkA-4bedA:
undetectable		 3qpkA-4bedA:
15.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QPK_B_CUB602_0
(LACCASE-1)		 1js8 HEMOCYANIN
(Enteroctopus
dofleini) 		3 / 3 HIS A2562
HIS A2571
HIS A2543
 CUO  A 888 (-3.4A)
CUO  A 888 (-3.3A)
CUO  A 888 (-3.4A)
 0.38A 3qpkB-1js8A:
undetectable		 3qpkB-1js8A:
18.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QPK_B_CUB602_0
(LACCASE-1)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		3 / 3 HIS A  60
HIS A  69
HIS A  42
 CUO  A9001 (-3.1A)
CUO  A9001 (-3.1A)
CUO  A9001 (-3.4A)
 0.35A 3qpkB-4bedA:
undetectable		 3qpkB-4bedA:
15.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QPK_B_CUB602_0
(LACCASE-1)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		3 / 3 HIS A 482
HIS A 491
HIS A 462
 CUO  A9002 (-3.4A)
CUO  A9002 (-3.4A)
CUO  A9002 (-3.2A)
 0.28A 3qpkB-4bedA:
undetectable		 3qpkB-4bedA:
15.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QPK_B_CUB602_0
(LACCASE-1)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		3 / 3 HIS A 896
HIS A 905
HIS A 876
 CUO  A9003 (-3.4A)
CUO  A9003 (-3.5A)
CUO  A9003 (-3.3A)
 0.28A 3qpkB-4bedA:
undetectable		 3qpkB-4bedA:
15.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QPK_B_CUB602_0
(LACCASE-1)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		3 / 3 HIS A1311
HIS A1320
HIS A1293
 CUO  A9004 (-3.4A)
CUO  A9004 (-3.5A)
CUO  A9004 (-3.2A)
 0.31A 3qpkB-4bedA:
undetectable		 3qpkB-4bedA:
15.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QPK_B_CUB602_0
(LACCASE-1)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		3 / 3 HIS B1725
HIS B1734
HIS B1705
 CUO  B9005 (-3.1A)
CUO  B9005 (-3.4A)
CUO  B9005 (-3.2A)
 0.35A 3qpkB-4bedB:
3.4		 3qpkB-4bedB:
15.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QPK_B_CUB602_0
(LACCASE-1)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		3 / 3 HIS B2141
HIS B2150
HIS B2122
 CUO  B9006 (-3.1A)
CUO  B9006 (-3.3A)
CUO  B9006 (-3.2A)
 0.33A 3qpkB-4bedB:
3.4		 3qpkB-4bedB:
15.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QPK_B_CUB602_0
(LACCASE-1)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		3 / 3 HIS B2561
HIS B2570
HIS B2542
 CUO  B9007 (-3.3A)
CUO  B9007 (-3.3A)
CUO  B9007 (-3.3A)
 0.39A 3qpkB-4bedB:
3.4		 3qpkB-4bedB:
15.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9F_E_CLME221_1
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		3 / 3 PHE B1730
CYH B1723
HIS B1734
 CUO  B9005 ( 4.9A)
CUO  B9005 ( 4.9A)
CUO  B9005 (-3.4A)
 1.29A 3u9fF-4bedB:
undetectable		 3u9fF-4bedB:
8.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W6H_A_AZMA303_1
(CARBONIC ANHYDRASE 1)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		4 / 8 HIS A 183
HIS A 179
HIS A 209
HIS A  69
 CUO  A9001 (-3.4A)
CUO  A9001 (-3.4A)
None
CUO  A9001 (-3.1A)
 1.04A 3w6hA-4bedA:
undetectable		 3w6hA-4bedA:
10.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W6H_A_AZMA303_1
(CARBONIC ANHYDRASE 1)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		4 / 8 HIS A1428
HIS A1424
HIS A1454
HIS A1320
 CUO  A9004 (-3.4A)
CUO  A9004 (-3.0A)
None
CUO  A9004 (-3.5A)
 1.06A 3w6hA-4bedA:
undetectable		 3w6hA-4bedA:
10.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W6H_A_AZMA303_1
(CARBONIC ANHYDRASE 1)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		4 / 8 HIS B1851
HIS B1847
HIS B1877
HIS B1734
 CUO  B9005 (-3.2A)
CUO  B9005 (-3.2A)
None
CUO  B9005 (-3.4A)
 1.05A 3w6hA-4bedB:
undetectable		 3w6hA-4bedB:
9.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W6H_A_AZMA303_1
(CARBONIC ANHYDRASE 1)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		4 / 8 HIS B2264
HIS B2260
HIS B2290
HIS B2150
 CUO  B9006 (-3.2A)
CUO  B9006 (-3.2A)
None
CUO  B9006 (-3.3A)
 1.02A 3w6hA-4bedB:
undetectable		 3w6hA-4bedB:
9.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W6H_A_AZMA303_1
(CARBONIC ANHYDRASE 1)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		4 / 8 HIS B2674
HIS B2670
HIS B2700
HIS B2570
 CUO  B9007 (-3.4A)
CUO  B9007 (-3.4A)
None
CUO  B9007 (-3.3A)
 1.05A 3w6hA-4bedB:
undetectable		 3w6hA-4bedB:
9.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WG7_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		3 / 3 HIS B2946
HIS B3106
HIS B2974
 CUO  B9008 (-3.1A)
CUO  B9008 (-3.3A)
CUO  B9008 (-2.9A)
 0.73A 3wg7A-4bedB:
undetectable		 3wg7A-4bedB:
14.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WG7_N_CUN603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		3 / 3 HIS B2946
HIS B3106
HIS B2974
 CUO  B9008 (-3.1A)
CUO  B9008 (-3.3A)
CUO  B9008 (-2.9A)
 0.75A 3wg7N-4bedB:
undetectable		 3wg7N-4bedB:
14.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3X2Q_A_CUA604_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		3 / 3 HIS B2946
HIS B3106
HIS B2974
 CUO  B9008 (-3.1A)
CUO  B9008 (-3.3A)
CUO  B9008 (-2.9A)
 0.70A 3x2qA-4bedB:
undetectable		 3x2qA-4bedB:
14.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3X2Q_N_CUN604_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		3 / 3 HIS B2946
HIS B3106
HIS B2974
 CUO  B9008 (-3.1A)
CUO  B9008 (-3.3A)
CUO  B9008 (-2.9A)
 0.67A 3x2qN-4bedB:
undetectable		 3x2qN-4bedB:
14.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A7B_A_HAEA1273_1
(COLLAGENASE 3)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		4 / 6 HIS A1454
HIS A1311
HIS A1320
HIS A1293
 None
CUO  A9004 (-3.4A)
CUO  A9004 (-3.5A)
CUO  A9004 (-3.2A)
 0.92A 4a7bA-4bedA:
undetectable		 4a7bA-4bedA:
7.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A7B_A_HAEA1273_1
(COLLAGENASE 3)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		4 / 6 HIS B2290
HIS B2141
HIS B2150
HIS B2122
 None
CUO  B9006 (-3.1A)
CUO  B9006 (-3.3A)
CUO  B9006 (-3.2A)
 0.91A 4a7bA-4bedB:
undetectable		 4a7bA-4bedB:
6.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BLV_A_SAMA1281_1
(RIBOSOMAL RNA LARGE
SUBUNIT
METHYLTRANSFERASE J)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		4 / 6 HIS A 491
HIS A 606
GLU A 595
ASP A 774
 CUO  A9002 (-3.4A)
CUO  A9002 (-3.3A)
None
None
 1.31A 4blvA-4bedA:
undetectable		 4blvA-4bedA:
11.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BLV_A_SAMA1281_1
(RIBOSOMAL RNA LARGE
SUBUNIT
METHYLTRANSFERASE J)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		4 / 6 HIS A 905
HIS A1019
GLU A1008
ASP A1188
 CUO  A9003 (-3.5A)
CUO  A9003 (-3.4A)
None
None
 1.36A 4blvA-4bedA:
undetectable		 4blvA-4bedA:
11.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BLV_A_SAMA1281_1
(RIBOSOMAL RNA LARGE
SUBUNIT
METHYLTRANSFERASE J)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		4 / 6 HIS B1734
HIS B1851
GLU B1840
ASP B2019
 CUO  B9005 (-3.4A)
CUO  B9005 (-3.2A)
None
None
 1.30A 4blvA-4bedB:
undetectable		 4blvA-4bedB:
10.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EF3_A_CUA1002_0
(BLUE COPPER OXIDASE
CUEO)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		4 / 4 HIS A 602
HIS A 606
HIS A 491
HIS A 633
 CUO  A9002 (-3.4A)
CUO  A9002 (-3.3A)
CUO  A9002 (-3.4A)
CUO  A9002 (-3.3A)
 1.18A 4ef3A-4bedA:
undetectable		 4ef3A-4bedA:
15.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EF3_A_CUA1002_0
(BLUE COPPER OXIDASE
CUEO)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		4 / 4 HIS A1015
HIS A1019
HIS A 905
HIS A1046
 CUO  A9003 (-3.1A)
CUO  A9003 (-3.4A)
CUO  A9003 (-3.5A)
CUO  A9003 (-3.2A)
 1.17A 4ef3A-4bedA:
undetectable		 4ef3A-4bedA:
15.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EF3_A_CUA1003_0
(BLUE COPPER OXIDASE
CUEO)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		5 / 5 HIS B3106
HIS B3075
HIS B2946
HIS B2974
HIS B2965
 CUO  B9008 (-3.3A)
CUO  B9008 (-2.8A)
CUO  B9008 (-3.1A)
CUO  B9008 (-2.9A)
CUO  B9008 (-3.2A)
 1.30A 4ef3A-4bedB:
undetectable		 4ef3A-4bedB:
15.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P6S_A_DAHA305_1
(TYROSINASE)		 1js8 HEMOCYANIN
(Enteroctopus
dofleini) 		5 / 7 HIS A2543
HIS A2562
HIS A2671
ASN A2672
HIS A2675
 CUO  A 888 (-3.4A)
CUO  A 888 (-3.4A)
CUO  A 888 (-3.4A)
None
CUO  A 888 (-3.3A)
 0.46A 4p6sA-1js8A:
23.9		 4p6sA-1js8A:
29.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P6S_A_DAHA305_1
(TYROSINASE)		 3wky PROPHENOLOXIDASE B
(Marsupenaeus
japonicus) 		7 / 7 HIS A 199
HIS A 203
HIS A 357
ASN A 358
HIS A 361
VAL A 384
ALA A 387
 CUO  A 708 (-3.3A)
CUO  A 708 (-3.5A)
CUO  A 708 (-3.3A)
None
CUO  A 708 (-3.2A)
None
None
 0.68A 4p6sA-3wkyA:
9.8		 4p6sA-3wkyA:
17.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P6S_A_DAHA305_1
(TYROSINASE)		 3wky PROPHENOLOXIDASE B
(Marsupenaeus
japonicus) 		4 / 7 HIS A 357
HIS A 361
HIS A 199
HIS A 203
 CUO  A 708 (-3.3A)
CUO  A 708 (-3.2A)
CUO  A 708 (-3.3A)
CUO  A 708 (-3.5A)
 0.78A 4p6sA-3wkyA:
9.8		 4p6sA-3wkyA:
17.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P6S_A_DAHA305_1
(TYROSINASE)		 3wky PROPHENOLOXIDASE B
(Marsupenaeus
japonicus) 		4 / 7 HIS A 361
HIS A 397
HIS A 199
ALA A 387
 CUO  A 708 (-3.2A)
CUO  A 708 (-3.4A)
CUO  A 708 (-3.3A)
None
 0.90A 4p6sA-3wkyA:
9.8		 4p6sA-3wkyA:
17.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P6S_A_DAHA305_1
(TYROSINASE)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		5 / 7 HIS A  42
HIS A  60
HIS A 179
ASN A 180
HIS A 183
 CUO  A9001 (-3.4A)
CUO  A9001 (-3.1A)
CUO  A9001 (-3.4A)
None
CUO  A9001 (-3.4A)
 0.93A 4p6sA-4bedA:
21.5		 4p6sA-4bedA:
10.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P6S_A_DAHA305_1
(TYROSINASE)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		5 / 7 HIS A 462
HIS A 482
HIS A 602
ASN A 603
HIS A 606
 CUO  A9002 (-3.2A)
CUO  A9002 (-3.4A)
CUO  A9002 (-3.4A)
None
CUO  A9002 (-3.3A)
 0.92A 4p6sA-4bedA:
21.5		 4p6sA-4bedA:
10.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P6S_A_DAHA305_1
(TYROSINASE)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		5 / 7 HIS A 876
HIS A 896
HIS A1015
ASN A1016
HIS A1019
 CUO  A9003 (-3.3A)
CUO  A9003 (-3.4A)
CUO  A9003 (-3.1A)
None
CUO  A9003 (-3.4A)
 1.02A 4p6sA-4bedA:
21.5		 4p6sA-4bedA:
10.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P6S_A_DAHA305_1
(TYROSINASE)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		5 / 7 HIS A1293
HIS A1311
ASN A1425
HIS A1428
ALA A1445
 CUO  A9004 (-3.2A)
CUO  A9004 (-3.4A)
None
CUO  A9004 (-3.4A)
None
 0.87A 4p6sA-4bedA:
21.5		 4p6sA-4bedA:
10.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P6S_A_DAHA305_1
(TYROSINASE)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		5 / 7 HIS A1293
HIS A1311
HIS A1424
HIS A1428
ALA A1445
 CUO  A9004 (-3.2A)
CUO  A9004 (-3.4A)
CUO  A9004 (-3.0A)
CUO  A9004 (-3.4A)
None
 0.78A 4p6sA-4bedA:
21.5		 4p6sA-4bedA:
10.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P6S_A_DAHA305_1
(TYROSINASE)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		5 / 7 HIS A1293
HIS A1320
HIS A1424
HIS A1428
ALA A1445
 CUO  A9004 (-3.2A)
CUO  A9004 (-3.5A)
CUO  A9004 (-3.0A)
CUO  A9004 (-3.4A)
None
 1.37A 4p6sA-4bedA:
21.5		 4p6sA-4bedA:
10.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P6S_A_DAHA305_1
(TYROSINASE)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		5 / 7 HIS A1428
HIS A1424
HIS A1320
HIS A1293
ALA A1445
 CUO  A9004 (-3.4A)
CUO  A9004 (-3.0A)
CUO  A9004 (-3.5A)
CUO  A9004 (-3.2A)
None
 1.44A 4p6sA-4bedA:
21.5		 4p6sA-4bedA:
10.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P6S_A_DAHA305_1
(TYROSINASE)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		4 / 7 HIS A1428
HIS A1455
HIS A1293
ALA A1445
 CUO  A9004 (-3.4A)
CUO  A9004 (-3.3A)
CUO  A9004 (-3.2A)
None
 0.82A 4p6sA-4bedA:
21.5		 4p6sA-4bedA:
10.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P6S_A_DAHA305_1
(TYROSINASE)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		6 / 7 HIS B1705
HIS B1725
HIS B1847
ASN B1848
HIS B1851
ALA B1868
 CUO  B9005 (-3.2A)
CUO  B9005 (-3.1A)
CUO  B9005 (-3.2A)
None
CUO  B9005 (-3.2A)
None
 0.77A 4p6sA-4bedB:
21.9		 4p6sA-4bedB:
9.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P6S_A_DAHA305_1
(TYROSINASE)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		5 / 7 HIS B1851
HIS B1847
HIS B1734
HIS B1705
ALA B1868
 CUO  B9005 (-3.2A)
CUO  B9005 (-3.2A)
CUO  B9005 (-3.4A)
CUO  B9005 (-3.2A)
None
 1.47A 4p6sA-4bedB:
21.9		 4p6sA-4bedB:
9.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P6S_A_DAHA305_1
(TYROSINASE)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		6 / 7 HIS B2122
HIS B2141
HIS B2260
ASN B2261
HIS B2264
ALA B2281
 CUO  B9006 (-3.2A)
CUO  B9006 (-3.1A)
CUO  B9006 (-3.2A)
None
CUO  B9006 (-3.2A)
None
 0.78A 4p6sA-4bedB:
21.9		 4p6sA-4bedB:
9.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P6S_A_DAHA305_1
(TYROSINASE)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		6 / 7 HIS B2122
HIS B2150
HIS B2260
ASN B2261
HIS B2264
ALA B2281
 CUO  B9006 (-3.2A)
CUO  B9006 (-3.3A)
CUO  B9006 (-3.2A)
None
CUO  B9006 (-3.2A)
None
 1.49A 4p6sA-4bedB:
21.9		 4p6sA-4bedB:
9.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P6S_A_DAHA305_1
(TYROSINASE)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		4 / 7 HIS B2264
HIS B2291
HIS B2122
ALA B2281
 CUO  B9006 (-3.2A)
CUO  B9006 (-3.5A)
CUO  B9006 (-3.2A)
None
 0.85A 4p6sA-4bedB:
21.9		 4p6sA-4bedB:
9.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P6S_A_DAHA305_1
(TYROSINASE)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		5 / 7 HIS B2542
HIS B2561
HIS B2670
ASN B2671
HIS B2674
 CUO  B9007 (-3.3A)
CUO  B9007 (-3.3A)
CUO  B9007 (-3.4A)
None
CUO  B9007 (-3.4A)
 0.85A 4p6sA-4bedB:
21.9		 4p6sA-4bedB:
9.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P6S_A_DAHA305_1
(TYROSINASE)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		4 / 7 HIS B2946
HIS B2965
HIS B3075
HIS B3079
 CUO  B9008 (-3.1A)
CUO  B9008 (-3.2A)
CUO  B9008 (-2.8A)
CUO  B9008 (-3.5A)
 0.54A 4p6sA-4bedB:
21.9		 4p6sA-4bedB:
9.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P6S_B_DAHB305_1
(TYROSINASE)		 1js8 HEMOCYANIN
(Enteroctopus
dofleini) 		5 / 7 HIS A2543
HIS A2562
HIS A2671
ASN A2672
HIS A2675
 CUO  A 888 (-3.4A)
CUO  A 888 (-3.4A)
CUO  A 888 (-3.4A)
None
CUO  A 888 (-3.3A)
 0.55A 4p6sB-1js8A:
23.9		 4p6sB-1js8A:
29.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P6S_B_DAHB305_1
(TYROSINASE)		 3wky PROPHENOLOXIDASE B
(Marsupenaeus
japonicus) 		6 / 7 HIS A 199
HIS A 203
HIS A 357
ASN A 358
HIS A 361
VAL A 384
 CUO  A 708 (-3.3A)
CUO  A 708 (-3.5A)
CUO  A 708 (-3.3A)
None
CUO  A 708 (-3.2A)
None
 0.75A 4p6sB-3wkyA:
9.9		 4p6sB-3wkyA:
17.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P6S_B_DAHB305_1
(TYROSINASE)		 3wky PROPHENOLOXIDASE B
(Marsupenaeus
japonicus) 		4 / 7 HIS A 357
HIS A 361
HIS A 199
HIS A 203
 CUO  A 708 (-3.3A)
CUO  A 708 (-3.2A)
CUO  A 708 (-3.3A)
CUO  A 708 (-3.5A)
 0.75A 4p6sB-3wkyA:
9.9		 4p6sB-3wkyA:
17.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P6S_B_DAHB305_1
(TYROSINASE)		 3wky PROPHENOLOXIDASE B
(Marsupenaeus
japonicus) 		4 / 7 HIS A 361
HIS A 357
HIS A 203
HIS A 199
 CUO  A 708 (-3.2A)
CUO  A 708 (-3.3A)
CUO  A 708 (-3.5A)
CUO  A 708 (-3.3A)
 0.99A 4p6sB-3wkyA:
9.9		 4p6sB-3wkyA:
17.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P6S_B_DAHB305_1
(TYROSINASE)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		4 / 7 HIS A  42
HIS A  60
HIS A 179
HIS A 183
 CUO  A9001 (-3.4A)
CUO  A9001 (-3.1A)
CUO  A9001 (-3.4A)
CUO  A9001 (-3.4A)
 0.88A 4p6sB-4bedA:
21.1		 4p6sB-4bedA:
10.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P6S_B_DAHB305_1
(TYROSINASE)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		5 / 7 HIS A 462
HIS A 482
HIS A 602
ASN A 603
HIS A 606
 CUO  A9002 (-3.2A)
CUO  A9002 (-3.4A)
CUO  A9002 (-3.4A)
None
CUO  A9002 (-3.3A)
 0.96A 4p6sB-4bedA:
21.1		 4p6sB-4bedA:
10.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P6S_B_DAHB305_1
(TYROSINASE)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		5 / 7 HIS A 876
HIS A 896
HIS A1015
ASN A1016
HIS A1019
 CUO  A9003 (-3.3A)
CUO  A9003 (-3.4A)
CUO  A9003 (-3.1A)
None
CUO  A9003 (-3.4A)
 1.03A 4p6sB-4bedA:
21.1		 4p6sB-4bedA:
10.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P6S_B_DAHB305_1
(TYROSINASE)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		4 / 7 HIS A1293
HIS A1311
ASN A1425
HIS A1428
 CUO  A9004 (-3.2A)
CUO  A9004 (-3.4A)
None
CUO  A9004 (-3.4A)
 0.91A 4p6sB-4bedA:
21.1		 4p6sB-4bedA:
10.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P6S_B_DAHB305_1
(TYROSINASE)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		4 / 7 HIS A1293
HIS A1311
HIS A1424
HIS A1428
 CUO  A9004 (-3.2A)
CUO  A9004 (-3.4A)
CUO  A9004 (-3.0A)
CUO  A9004 (-3.4A)
 0.81A 4p6sB-4bedA:
21.1		 4p6sB-4bedA:
10.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P6S_B_DAHB305_1
(TYROSINASE)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		5 / 7 HIS B1705
HIS B1725
HIS B1847
ASN B1848
HIS B1851
 CUO  B9005 (-3.2A)
CUO  B9005 (-3.1A)
CUO  B9005 (-3.2A)
None
CUO  B9005 (-3.2A)
 0.83A 4p6sB-4bedB:
10.1		 4p6sB-4bedB:
9.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P6S_B_DAHB305_1
(TYROSINASE)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		5 / 7 HIS B2122
HIS B2141
HIS B2260
ASN B2261
HIS B2264
 CUO  B9006 (-3.2A)
CUO  B9006 (-3.1A)
CUO  B9006 (-3.2A)
None
CUO  B9006 (-3.2A)
 0.85A 4p6sB-4bedB:
10.1		 4p6sB-4bedB:
9.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P6S_B_DAHB305_1
(TYROSINASE)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		4 / 7 HIS B2542
HIS B2561
HIS B2670
HIS B2674
 CUO  B9007 (-3.3A)
CUO  B9007 (-3.3A)
CUO  B9007 (-3.4A)
CUO  B9007 (-3.4A)
 0.77A 4p6sB-4bedB:
10.1		 4p6sB-4bedB:
9.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P6S_B_DAHB305_1
(TYROSINASE)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		4 / 7 HIS B2946
HIS B2965
HIS B3075
HIS B3079
 CUO  B9008 (-3.1A)
CUO  B9008 (-3.2A)
CUO  B9008 (-2.8A)
CUO  B9008 (-3.5A)
 0.66A 4p6sB-4bedB:
10.1		 4p6sB-4bedB:
9.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P6S_B_DAHB305_1
(TYROSINASE)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		4 / 7 HIS B2946
HIS B3075
ASN B3076
HIS B3079
 CUO  B9008 (-3.1A)
CUO  B9008 (-2.8A)
None
CUO  B9008 (-3.5A)
 0.49A 4p6sB-4bedB:
10.1		 4p6sB-4bedB:
9.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PEV_C_ADNC501_2
(MEMBRANE LIPOPROTEIN
FAMILY PROTEIN)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		3 / 3 PRO A 669
VAL A 481
HIS A 482
 None
None
CUO  A9002 (-3.4A)
 0.83A 4pevC-4bedA:
undetectable		 4pevC-4bedA:
13.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PEV_C_ADNC501_2
(MEMBRANE LIPOPROTEIN
FAMILY PROTEIN)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		3 / 3 PRO B3143
VAL B2964
HIS B2965
 None
None
CUO  B9008 (-3.2A)
 0.64A 4pevC-4bedB:
undetectable		 4pevC-4bedB:
13.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Q15_A_HFGA803_1
(PROLINE--TRNA LIGASE)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		3 / 3 GLU A 349
THR A 200
HIS A  42
 None
CUO  A9001 ( 4.9A)
CUO  A9001 (-3.4A)
 0.82A 4q15A-4bedA:
undetectable		 4q15A-4bedA:
15.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Q15_B_HFGB803_1
(PROLINE--TRNA LIGASE)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		3 / 3 GLU A 349
THR A 200
HIS A  42
 None
CUO  A9001 ( 4.9A)
CUO  A9001 (-3.4A)
 0.78A 4q15B-4bedA:
undetectable		 4q15B-4bedA:
15.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R88_A_1LDA501_0
(CYTOSINE DEAMINASE)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		5 / 12 HIS B2974
LEU B3093
PHE B2970
HIS B3075
HIS B3079
 CUO  B9008 (-2.9A)
None
None
CUO  B9008 (-2.8A)
CUO  B9008 (-3.5A)
 1.35A 4r88A-4bedB:
undetectable		 4r88A-4bedB:
13.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WCX_C_SAMC503_1
(BIOTIN AND THIAMIN
SYNTHESIS ASSOCIATED)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		4 / 6 CYH A 894
ASN A1016
LEU A1176
GLU A1182
 CUO  A9003 (-3.1A)
None
None
None
 1.11A 4wcxC-4bedA:
undetectable		 4wcxC-4bedA:
15.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YDQ_B_HFGB802_1
(PROLINE--TRNA LIGASE)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		3 / 3 GLU A 349
THR A 200
HIS A  42
 None
CUO  A9001 ( 4.9A)
CUO  A9001 (-3.4A)
 0.78A 4ydqB-4bedA:
undetectable		 4ydqB-4bedA:
15.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1A_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		3 / 3 HIS B2946
HIS B3106
HIS B2974
 CUO  B9008 (-3.1A)
CUO  B9008 (-3.3A)
CUO  B9008 (-2.9A)
 0.71A 5b1aA-4bedB:
undetectable		 5b1aA-4bedB:
14.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1A_N_CUN603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		3 / 3 HIS B2946
HIS B3106
HIS B2974
 CUO  B9008 (-3.1A)
CUO  B9008 (-3.3A)
CUO  B9008 (-2.9A)
 0.74A 5b1aN-4bedB:
0.3		 5b1aN-4bedB:
14.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1B_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1js8 HEMOCYANIN
(Enteroctopus
dofleini) 		3 / 3 HIS A2671
HIS A2702
HIS A2701
 CUO  A 888 (-3.4A)
CUO  A 888 (-3.3A)
None
 0.72A 5b1bA-1js8A:
undetectable		 5b1bA-1js8A:
21.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1B_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		3 / 3 HIS B2946
HIS B3106
HIS B2974
 CUO  B9008 (-3.1A)
CUO  B9008 (-3.3A)
CUO  B9008 (-2.9A)
 0.67A 5b1bA-4bedB:
undetectable		 5b1bA-4bedB:
14.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1B_N_CUN603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		3 / 3 HIS B2946
HIS B3106
HIS B2974
 CUO  B9008 (-3.1A)
CUO  B9008 (-3.3A)
CUO  B9008 (-2.9A)
 0.69A 5b1bN-4bedB:
undetectable		 5b1bN-4bedB:
14.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B3S_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		3 / 3 HIS B2946
HIS B3106
HIS B2974
 CUO  B9008 (-3.1A)
CUO  B9008 (-3.3A)
CUO  B9008 (-2.9A)
 0.70A 5b3sA-4bedB:
undetectable		 5b3sA-4bedB:
14.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B3S_N_CUN603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1js8 HEMOCYANIN
(Enteroctopus
dofleini) 		3 / 3 HIS A2671
HIS A2702
HIS A2701
 CUO  A 888 (-3.4A)
CUO  A 888 (-3.3A)
None
 0.74A 5b3sN-1js8A:
0.6		 5b3sN-1js8A:
21.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B3S_N_CUN603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		3 / 3 HIS B2946
HIS B3106
HIS B2974
 CUO  B9008 (-3.1A)
CUO  B9008 (-3.3A)
CUO  B9008 (-2.9A)
 0.73A 5b3sN-4bedB:
undetectable		 5b3sN-4bedB:
14.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUQ_A_ACTA1278_0
(NAD(P)H
DEHYDROGENASE
[QUINONE] 1)		 1js8 HEMOCYANIN
(Enteroctopus
dofleini) 		4 / 5 HIS A2543
SER A2693
ILE A2545
TYR A2691
 CUO  A 888 (-3.4A)
None
None
None
 1.45A 5fuqA-1js8A:
0.0
5fuqB-1js8A:
0.0		 5fuqA-1js8A:
19.90
5fuqB-1js8A:
19.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GWY_E_010E6_0
(N-[(5-METHYLISOXAZOL
-3-YL)CARBONYL]ALANY
L-L-VALYL-N~1~-((1R,
2Z)-4-(BENZYLOXY)-4-
OXO-1-{[(3R)-2-OXOPY
RROLIDIN-3-YL]METHYL
}BUT-2-ENYL)-L-LEUCI
NAMIDE
MAIN PROTEASE)		 1js8 HEMOCYANIN
(Enteroctopus
dofleini) 		4 / 4 THR A2692
LEU A2689
HIS A2562
GLY A2544
 CUO  A 888 ( 4.9A)
None
CUO  A 888 (-3.4A)
None
 1.20A 5gwyA-1js8A:
1.2		 5gwyA-1js8A:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GWY_E_010E6_0
(N-[(5-METHYLISOXAZOL
-3-YL)CARBONYL]ALANY
L-L-VALYL-N~1~-((1R,
2Z)-4-(BENZYLOXY)-4-
OXO-1-{[(3R)-2-OXOPY
RROLIDIN-3-YL]METHYL
}BUT-2-ENYL)-L-LEUCI
NAMIDE
MAIN PROTEASE)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		4 / 4 THR A 200
LEU A 197
HIS A  60
GLY A  43
 CUO  A9001 ( 4.9A)
None
CUO  A9001 (-3.1A)
None
 1.25A 5gwyA-4bedA:
undetectable		 5gwyA-4bedA:
10.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GWY_E_010E6_0
(N-[(5-METHYLISOXAZOL
-3-YL)CARBONYL]ALANY
L-L-VALYL-N~1~-((1R,
2Z)-4-(BENZYLOXY)-4-
OXO-1-{[(3R)-2-OXOPY
RROLIDIN-3-YL]METHYL
}BUT-2-ENYL)-L-LEUCI
NAMIDE
MAIN PROTEASE)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		4 / 4 THR A 623
LEU A 620
HIS A 482
GLY A 463
 CUO  A9002 ( 4.5A)
None
CUO  A9002 (-3.4A)
None
 1.31A 5gwyA-4bedA:
undetectable		 5gwyA-4bedA:
10.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GWY_E_010E6_0
(N-[(5-METHYLISOXAZOL
-3-YL)CARBONYL]ALANY
L-L-VALYL-N~1~-((1R,
2Z)-4-(BENZYLOXY)-4-
OXO-1-{[(3R)-2-OXOPY
RROLIDIN-3-YL]METHYL
}BUT-2-ENYL)-L-LEUCI
NAMIDE
MAIN PROTEASE)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		4 / 4 THR A1036
LEU A1033
HIS A 896
GLY A 877
 None
None
CUO  A9003 (-3.4A)
None
 1.31A 5gwyA-4bedA:
undetectable		 5gwyA-4bedA:
10.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GWY_E_010E6_0
(N-[(5-METHYLISOXAZOL
-3-YL)CARBONYL]ALANY
L-L-VALYL-N~1~-((1R,
2Z)-4-(BENZYLOXY)-4-
OXO-1-{[(3R)-2-OXOPY
RROLIDIN-3-YL]METHYL
}BUT-2-ENYL)-L-LEUCI
NAMIDE
MAIN PROTEASE)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		4 / 4 THR B2691
LEU B2688
HIS B2561
GLY B2543
 CUO  B9007 ( 4.5A)
None
CUO  B9007 (-3.3A)
None
 1.21A 5gwyA-4bedB:
undetectable		 5gwyA-4bedB:
10.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3A_A_HQEA303_1
(TYROSINASE)		 1js8 HEMOCYANIN
(Enteroctopus
dofleini) 		5 / 7 HIS A2543
HIS A2562
HIS A2671
ASN A2672
HIS A2675
 CUO  A 888 (-3.4A)
CUO  A 888 (-3.4A)
CUO  A 888 (-3.4A)
None
CUO  A 888 (-3.3A)
 0.45A 5i3aA-1js8A:
24.1		 5i3aA-1js8A:
29.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3A_A_HQEA303_1
(TYROSINASE)		 3wky PROPHENOLOXIDASE B
(Marsupenaeus
japonicus) 		7 / 7 HIS A 199
HIS A 203
HIS A 357
ASN A 358
HIS A 361
VAL A 384
ALA A 387
 CUO  A 708 (-3.3A)
CUO  A 708 (-3.5A)
CUO  A 708 (-3.3A)
None
CUO  A 708 (-3.2A)
None
None
 0.69A 5i3aA-3wkyA:
9.9		 5i3aA-3wkyA:
17.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3A_A_HQEA303_1
(TYROSINASE)		 3wky PROPHENOLOXIDASE B
(Marsupenaeus
japonicus) 		4 / 7 HIS A 357
HIS A 361
HIS A 199
HIS A 203
 CUO  A 708 (-3.3A)
CUO  A 708 (-3.2A)
CUO  A 708 (-3.3A)
CUO  A 708 (-3.5A)
 0.77A 5i3aA-3wkyA:
9.9		 5i3aA-3wkyA:
17.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3A_A_HQEA303_1
(TYROSINASE)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		5 / 7 HIS A  42
HIS A  60
HIS A 179
ASN A 180
HIS A 183
 CUO  A9001 (-3.4A)
CUO  A9001 (-3.1A)
CUO  A9001 (-3.4A)
None
CUO  A9001 (-3.4A)
 0.95A 5i3aA-4bedA:
21.3		 5i3aA-4bedA:
10.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3A_A_HQEA303_1
(TYROSINASE)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		5 / 7 HIS A 462
HIS A 482
HIS A 602
ASN A 603
HIS A 606
 CUO  A9002 (-3.2A)
CUO  A9002 (-3.4A)
CUO  A9002 (-3.4A)
None
CUO  A9002 (-3.3A)
 0.95A 5i3aA-4bedA:
21.3		 5i3aA-4bedA:
10.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3A_A_HQEA303_1
(TYROSINASE)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		5 / 7 HIS A 876
HIS A 896
HIS A1015
ASN A1016
HIS A1019
 CUO  A9003 (-3.3A)
CUO  A9003 (-3.4A)
CUO  A9003 (-3.1A)
None
CUO  A9003 (-3.4A)
 1.04A 5i3aA-4bedA:
21.3		 5i3aA-4bedA:
10.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3A_A_HQEA303_1
(TYROSINASE)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		5 / 7 HIS A1293
HIS A1311
ASN A1425
HIS A1428
ALA A1445
 CUO  A9004 (-3.2A)
CUO  A9004 (-3.4A)
None
CUO  A9004 (-3.4A)
None
 0.88A 5i3aA-4bedA:
21.3		 5i3aA-4bedA:
10.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3A_A_HQEA303_1
(TYROSINASE)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		5 / 7 HIS A1293
HIS A1311
HIS A1424
HIS A1428
ALA A1445
 CUO  A9004 (-3.2A)
CUO  A9004 (-3.4A)
CUO  A9004 (-3.0A)
CUO  A9004 (-3.4A)
None
 0.80A 5i3aA-4bedA:
21.3		 5i3aA-4bedA:
10.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3A_A_HQEA303_1
(TYROSINASE)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		5 / 7 HIS A1293
HIS A1320
HIS A1424
HIS A1428
ALA A1445
 CUO  A9004 (-3.2A)
CUO  A9004 (-3.5A)
CUO  A9004 (-3.0A)
CUO  A9004 (-3.4A)
None
 1.33A 5i3aA-4bedA:
21.3		 5i3aA-4bedA:
10.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3A_A_HQEA303_1
(TYROSINASE)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		5 / 7 HIS A1428
HIS A1424
HIS A1320
HIS A1293
ALA A1445
 CUO  A9004 (-3.4A)
CUO  A9004 (-3.0A)
CUO  A9004 (-3.5A)
CUO  A9004 (-3.2A)
None
 1.41A 5i3aA-4bedA:
21.3		 5i3aA-4bedA:
10.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3A_A_HQEA303_1
(TYROSINASE)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		4 / 7 HIS A1428
HIS A1455
HIS A1293
ALA A1445
 CUO  A9004 (-3.4A)
CUO  A9004 (-3.3A)
CUO  A9004 (-3.2A)
None
 0.88A 5i3aA-4bedA:
21.3		 5i3aA-4bedA:
10.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3A_A_HQEA303_1
(TYROSINASE)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		6 / 7 HIS B1705
HIS B1725
HIS B1847
ASN B1848
HIS B1851
ALA B1868
 CUO  B9005 (-3.2A)
CUO  B9005 (-3.1A)
CUO  B9005 (-3.2A)
None
CUO  B9005 (-3.2A)
None
 0.79A 5i3aA-4bedB:
23.8		 5i3aA-4bedB:
9.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3A_A_HQEA303_1
(TYROSINASE)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		5 / 7 HIS B1851
HIS B1847
HIS B1734
HIS B1705
ALA B1868
 CUO  B9005 (-3.2A)
CUO  B9005 (-3.2A)
CUO  B9005 (-3.4A)
CUO  B9005 (-3.2A)
None
 1.44A 5i3aA-4bedB:
23.8		 5i3aA-4bedB:
9.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3A_A_HQEA303_1
(TYROSINASE)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		6 / 7 HIS B2122
HIS B2141
HIS B2260
ASN B2261
HIS B2264
ALA B2281
 CUO  B9006 (-3.2A)
CUO  B9006 (-3.1A)
CUO  B9006 (-3.2A)
None
CUO  B9006 (-3.2A)
None
 0.82A 5i3aA-4bedB:
23.8		 5i3aA-4bedB:
9.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3A_A_HQEA303_1
(TYROSINASE)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		6 / 7 HIS B2122
HIS B2150
HIS B2260
ASN B2261
HIS B2264
ALA B2281
 CUO  B9006 (-3.2A)
CUO  B9006 (-3.3A)
CUO  B9006 (-3.2A)
None
CUO  B9006 (-3.2A)
None
 1.48A 5i3aA-4bedB:
23.8		 5i3aA-4bedB:
9.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3A_A_HQEA303_1
(TYROSINASE)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		4 / 7 HIS B2264
HIS B2291
HIS B2122
ALA B2281
 CUO  B9006 (-3.2A)
CUO  B9006 (-3.5A)
CUO  B9006 (-3.2A)
None
 0.90A 5i3aA-4bedB:
23.8		 5i3aA-4bedB:
9.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3A_A_HQEA303_1
(TYROSINASE)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		5 / 7 HIS B2542
HIS B2561
HIS B2670
ASN B2671
HIS B2674
 CUO  B9007 (-3.3A)
CUO  B9007 (-3.3A)
CUO  B9007 (-3.4A)
None
CUO  B9007 (-3.4A)
 0.87A 5i3aA-4bedB:
23.8		 5i3aA-4bedB:
9.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3A_A_HQEA303_1
(TYROSINASE)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		4 / 7 HIS B2946
HIS B2965
HIS B3075
HIS B3079
 CUO  B9008 (-3.1A)
CUO  B9008 (-3.2A)
CUO  B9008 (-2.8A)
CUO  B9008 (-3.5A)
 0.63A 5i3aA-4bedB:
23.8		 5i3aA-4bedB:
9.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3A_B_HQEB304_1
(TYROSINASE)		 1js8 HEMOCYANIN
(Enteroctopus
dofleini) 		5 / 7 HIS A2543
HIS A2562
HIS A2671
ASN A2672
HIS A2675
 CUO  A 888 (-3.4A)
CUO  A 888 (-3.4A)
CUO  A 888 (-3.4A)
None
CUO  A 888 (-3.3A)
 0.45A 5i3aB-1js8A:
24.0		 5i3aB-1js8A:
29.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3A_B_HQEB304_1
(TYROSINASE)		 3wky PROPHENOLOXIDASE B
(Marsupenaeus
japonicus) 		7 / 7 HIS A 199
HIS A 203
HIS A 357
ASN A 358
HIS A 361
VAL A 384
ALA A 387
 CUO  A 708 (-3.3A)
CUO  A 708 (-3.5A)
CUO  A 708 (-3.3A)
None
CUO  A 708 (-3.2A)
None
None
 0.71A 5i3aB-3wkyA:
9.9		 5i3aB-3wkyA:
17.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3A_B_HQEB304_1
(TYROSINASE)		 3wky PROPHENOLOXIDASE B
(Marsupenaeus
japonicus) 		4 / 7 HIS A 357
HIS A 361
HIS A 199
HIS A 203
 CUO  A 708 (-3.3A)
CUO  A 708 (-3.2A)
CUO  A 708 (-3.3A)
CUO  A 708 (-3.5A)
 0.76A 5i3aB-3wkyA:
9.9		 5i3aB-3wkyA:
17.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3A_B_HQEB304_1
(TYROSINASE)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		5 / 7 HIS A  42
HIS A  60
HIS A 179
ASN A 180
HIS A 183
 CUO  A9001 (-3.4A)
CUO  A9001 (-3.1A)
CUO  A9001 (-3.4A)
None
CUO  A9001 (-3.4A)
 0.94A 5i3aB-4bedA:
21.3		 5i3aB-4bedA:
10.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3A_B_HQEB304_1
(TYROSINASE)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		5 / 7 HIS A 462
HIS A 482
HIS A 602
ASN A 603
HIS A 606
 CUO  A9002 (-3.2A)
CUO  A9002 (-3.4A)
CUO  A9002 (-3.4A)
None
CUO  A9002 (-3.3A)
 0.93A 5i3aB-4bedA:
21.3		 5i3aB-4bedA:
10.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3A_B_HQEB304_1
(TYROSINASE)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		5 / 7 HIS A 876
HIS A 896
HIS A1015
ASN A1016
HIS A1019
 CUO  A9003 (-3.3A)
CUO  A9003 (-3.4A)
CUO  A9003 (-3.1A)
None
CUO  A9003 (-3.4A)
 1.02A 5i3aB-4bedA:
21.3		 5i3aB-4bedA:
10.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3A_B_HQEB304_1
(TYROSINASE)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		5 / 7 HIS A1293
HIS A1311
ASN A1425
HIS A1428
ALA A1445
 CUO  A9004 (-3.2A)
CUO  A9004 (-3.4A)
None
CUO  A9004 (-3.4A)
None
 0.86A 5i3aB-4bedA:
21.3		 5i3aB-4bedA:
10.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3A_B_HQEB304_1
(TYROSINASE)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		5 / 7 HIS A1293
HIS A1311
HIS A1424
HIS A1428
ALA A1445
 CUO  A9004 (-3.2A)
CUO  A9004 (-3.4A)
CUO  A9004 (-3.0A)
CUO  A9004 (-3.4A)
None
 0.77A 5i3aB-4bedA:
21.3		 5i3aB-4bedA:
10.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3A_B_HQEB304_1
(TYROSINASE)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		5 / 7 HIS A1293
HIS A1320
HIS A1424
HIS A1428
ALA A1445
 CUO  A9004 (-3.2A)
CUO  A9004 (-3.5A)
CUO  A9004 (-3.0A)
CUO  A9004 (-3.4A)
None
 1.37A 5i3aB-4bedA:
21.3		 5i3aB-4bedA:
10.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3A_B_HQEB304_1
(TYROSINASE)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		5 / 7 HIS A1428
HIS A1424
HIS A1320
HIS A1293
ALA A1445
 CUO  A9004 (-3.4A)
CUO  A9004 (-3.0A)
CUO  A9004 (-3.5A)
CUO  A9004 (-3.2A)
None
 1.43A 5i3aB-4bedA:
21.3		 5i3aB-4bedA:
10.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3A_B_HQEB304_1
(TYROSINASE)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		4 / 7 HIS A1428
HIS A1455
HIS A1293
ALA A1445
 CUO  A9004 (-3.4A)
CUO  A9004 (-3.3A)
CUO  A9004 (-3.2A)
None
 0.88A 5i3aB-4bedA:
21.3		 5i3aB-4bedA:
10.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3A_B_HQEB304_1
(TYROSINASE)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		6 / 7 HIS B1705
HIS B1725
HIS B1847
ASN B1848
HIS B1851
ALA B1868
 CUO  B9005 (-3.2A)
CUO  B9005 (-3.1A)
CUO  B9005 (-3.2A)
None
CUO  B9005 (-3.2A)
None
 0.78A 5i3aB-4bedB:
23.7		 5i3aB-4bedB:
9.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3A_B_HQEB304_1
(TYROSINASE)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		5 / 7 HIS B1851
HIS B1847
HIS B1734
HIS B1705
ALA B1868
 CUO  B9005 (-3.2A)
CUO  B9005 (-3.2A)
CUO  B9005 (-3.4A)
CUO  B9005 (-3.2A)
None
 1.45A 5i3aB-4bedB:
23.7		 5i3aB-4bedB:
9.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3A_B_HQEB304_1
(TYROSINASE)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		6 / 7 HIS B2122
HIS B2141
HIS B2260
ASN B2261
HIS B2264
ALA B2281
 CUO  B9006 (-3.2A)
CUO  B9006 (-3.1A)
CUO  B9006 (-3.2A)
None
CUO  B9006 (-3.2A)
None
 0.81A 5i3aB-4bedB:
23.7		 5i3aB-4bedB:
9.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3A_B_HQEB304_1
(TYROSINASE)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		4 / 7 HIS B2264
HIS B2291
HIS B2122
ALA B2281
 CUO  B9006 (-3.2A)
CUO  B9006 (-3.5A)
CUO  B9006 (-3.2A)
None
 0.88A 5i3aB-4bedB:
23.7		 5i3aB-4bedB:
9.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3A_B_HQEB304_1
(TYROSINASE)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		5 / 7 HIS B2542
HIS B2561
HIS B2670
ASN B2671
HIS B2674
 CUO  B9007 (-3.3A)
CUO  B9007 (-3.3A)
CUO  B9007 (-3.4A)
None
CUO  B9007 (-3.4A)
 0.88A 5i3aB-4bedB:
23.7		 5i3aB-4bedB:
9.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3A_B_HQEB304_1
(TYROSINASE)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		4 / 7 HIS B2946
HIS B2965
HIS B3075
HIS B3079
 CUO  B9008 (-3.1A)
CUO  B9008 (-3.2A)
CUO  B9008 (-2.8A)
CUO  B9008 (-3.5A)
 0.65A 5i3aB-4bedB:
23.7		 5i3aB-4bedB:
9.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3A_B_HQEB304_1
(TYROSINASE)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		4 / 7 HIS B2946
HIS B3075
ASN B3076
HIS B3079
 CUO  B9008 (-3.1A)
CUO  B9008 (-2.8A)
None
CUO  B9008 (-3.5A)
 0.49A 5i3aB-4bedB:
23.7		 5i3aB-4bedB:
9.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3B_A_HQEA303_1
(TYROSINASE)		 1js8 HEMOCYANIN
(Enteroctopus
dofleini) 		5 / 7 HIS A2543
HIS A2562
HIS A2671
ASN A2672
HIS A2675
 CUO  A 888 (-3.4A)
CUO  A 888 (-3.4A)
CUO  A 888 (-3.4A)
None
CUO  A 888 (-3.3A)
 0.46A 5i3bA-1js8A:
24.0		 5i3bA-1js8A:
29.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3B_A_HQEA303_1
(TYROSINASE)		 3wky PROPHENOLOXIDASE B
(Marsupenaeus
japonicus) 		7 / 7 HIS A 199
HIS A 203
HIS A 357
ASN A 358
HIS A 361
VAL A 384
ALA A 387
 CUO  A 708 (-3.3A)
CUO  A 708 (-3.5A)
CUO  A 708 (-3.3A)
None
CUO  A 708 (-3.2A)
None
None
 0.70A 5i3bA-3wkyA:
10.1		 5i3bA-3wkyA:
17.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3B_A_HQEA303_1
(TYROSINASE)		 3wky PROPHENOLOXIDASE B
(Marsupenaeus
japonicus) 		4 / 7 HIS A 357
HIS A 361
HIS A 199
HIS A 203
 CUO  A 708 (-3.3A)
CUO  A 708 (-3.2A)
CUO  A 708 (-3.3A)
CUO  A 708 (-3.5A)
 0.80A 5i3bA-3wkyA:
10.1		 5i3bA-3wkyA:
17.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3B_A_HQEA303_1
(TYROSINASE)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		5 / 7 HIS A  42
HIS A  60
HIS A 179
ASN A 180
HIS A 183
 CUO  A9001 (-3.4A)
CUO  A9001 (-3.1A)
CUO  A9001 (-3.4A)
None
CUO  A9001 (-3.4A)
 0.96A 5i3bA-4bedA:
21.3		 5i3bA-4bedA:
10.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3B_A_HQEA303_1
(TYROSINASE)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		5 / 7 HIS A  42
HIS A  69
HIS A 179
ASN A 180
HIS A 183
 CUO  A9001 (-3.4A)
CUO  A9001 (-3.1A)
CUO  A9001 (-3.4A)
None
CUO  A9001 (-3.4A)
 1.50A 5i3bA-4bedA:
21.3		 5i3bA-4bedA:
10.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3B_A_HQEA303_1
(TYROSINASE)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		5 / 7 HIS A 462
HIS A 482
HIS A 602
ASN A 603
HIS A 606
 CUO  A9002 (-3.2A)
CUO  A9002 (-3.4A)
CUO  A9002 (-3.4A)
None
CUO  A9002 (-3.3A)
 0.95A 5i3bA-4bedA:
21.3		 5i3bA-4bedA:
10.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3B_A_HQEA303_1
(TYROSINASE)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		5 / 7 HIS A 876
HIS A 896
HIS A1015
ASN A1016
HIS A1019
 CUO  A9003 (-3.3A)
CUO  A9003 (-3.4A)
CUO  A9003 (-3.1A)
None
CUO  A9003 (-3.4A)
 1.05A 5i3bA-4bedA:
21.3		 5i3bA-4bedA:
10.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3B_A_HQEA303_1
(TYROSINASE)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		5 / 7 HIS A1293
HIS A1311
ASN A1425
HIS A1428
ALA A1445
 CUO  A9004 (-3.2A)
CUO  A9004 (-3.4A)
None
CUO  A9004 (-3.4A)
None
 0.89A 5i3bA-4bedA:
21.3		 5i3bA-4bedA:
10.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3B_A_HQEA303_1
(TYROSINASE)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		5 / 7 HIS A1293
HIS A1311
HIS A1424
HIS A1428
ALA A1445
 CUO  A9004 (-3.2A)
CUO  A9004 (-3.4A)
CUO  A9004 (-3.0A)
CUO  A9004 (-3.4A)
None
 0.80A 5i3bA-4bedA:
21.3		 5i3bA-4bedA:
10.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3B_A_HQEA303_1
(TYROSINASE)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		5 / 7 HIS A1293
HIS A1320
HIS A1424
HIS A1428
ALA A1445
 CUO  A9004 (-3.2A)
CUO  A9004 (-3.5A)
CUO  A9004 (-3.0A)
CUO  A9004 (-3.4A)
None
 1.32A 5i3bA-4bedA:
21.3		 5i3bA-4bedA:
10.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3B_A_HQEA303_1
(TYROSINASE)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		5 / 7 HIS A1428
HIS A1424
HIS A1311
HIS A1293
ALA A1445
 CUO  A9004 (-3.4A)
CUO  A9004 (-3.0A)
CUO  A9004 (-3.4A)
CUO  A9004 (-3.2A)
None
 1.30A 5i3bA-4bedA:
21.3		 5i3bA-4bedA:
10.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3B_A_HQEA303_1
(TYROSINASE)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		5 / 7 HIS A1428
HIS A1424
HIS A1320
HIS A1293
ALA A1445
 CUO  A9004 (-3.4A)
CUO  A9004 (-3.0A)
CUO  A9004 (-3.5A)
CUO  A9004 (-3.2A)
None
 1.40A 5i3bA-4bedA:
21.3		 5i3bA-4bedA:
10.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3B_A_HQEA303_1
(TYROSINASE)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		4 / 7 HIS A1428
HIS A1455
HIS A1293
ALA A1445
 CUO  A9004 (-3.4A)
CUO  A9004 (-3.3A)
CUO  A9004 (-3.2A)
None
 0.88A 5i3bA-4bedA:
21.3		 5i3bA-4bedA:
10.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3B_A_HQEA303_1
(TYROSINASE)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		6 / 7 HIS B1705
HIS B1725
HIS B1847
ASN B1848
HIS B1851
ALA B1868
 CUO  B9005 (-3.2A)
CUO  B9005 (-3.1A)
CUO  B9005 (-3.2A)
None
CUO  B9005 (-3.2A)
None
 0.80A 5i3bA-4bedB:
23.8		 5i3bA-4bedB:
9.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3B_A_HQEA303_1
(TYROSINASE)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		5 / 7 HIS B1851
HIS B1847
HIS B1734
HIS B1705
ALA B1868
 CUO  B9005 (-3.2A)
CUO  B9005 (-3.2A)
CUO  B9005 (-3.4A)
CUO  B9005 (-3.2A)
None
 1.43A 5i3bA-4bedB:
23.8		 5i3bA-4bedB:
9.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3B_A_HQEA303_1
(TYROSINASE)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		6 / 7 HIS B2122
HIS B2141
HIS B2260
ASN B2261
HIS B2264
ALA B2281
 CUO  B9006 (-3.2A)
CUO  B9006 (-3.1A)
CUO  B9006 (-3.2A)
None
CUO  B9006 (-3.2A)
None
 0.83A 5i3bA-4bedB:
23.8		 5i3bA-4bedB:
9.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3B_A_HQEA303_1
(TYROSINASE)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		6 / 7 HIS B2122
HIS B2150
HIS B2260
ASN B2261
HIS B2264
ALA B2281
 CUO  B9006 (-3.2A)
CUO  B9006 (-3.3A)
CUO  B9006 (-3.2A)
None
CUO  B9006 (-3.2A)
None
 1.47A 5i3bA-4bedB:
23.8		 5i3bA-4bedB:
9.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3B_A_HQEA303_1
(TYROSINASE)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		4 / 7 HIS B2264
HIS B2291
HIS B2122
ALA B2281
 CUO  B9006 (-3.2A)
CUO  B9006 (-3.5A)
CUO  B9006 (-3.2A)
None
 0.91A 5i3bA-4bedB:
23.8		 5i3bA-4bedB:
9.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3B_A_HQEA303_1
(TYROSINASE)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		5 / 7 HIS B2542
HIS B2561
HIS B2670
ASN B2671
HIS B2674
 CUO  B9007 (-3.3A)
CUO  B9007 (-3.3A)
CUO  B9007 (-3.4A)
None
CUO  B9007 (-3.4A)
 0.88A 5i3bA-4bedB:
23.8		 5i3bA-4bedB:
9.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3B_A_HQEA303_1
(TYROSINASE)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		4 / 7 HIS B2946
HIS B2965
HIS B3075
HIS B3079
 CUO  B9008 (-3.1A)
CUO  B9008 (-3.2A)
CUO  B9008 (-2.8A)
CUO  B9008 (-3.5A)
 0.59A 5i3bA-4bedB:
23.8		 5i3bA-4bedB:
9.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3B_B_HQEB303_1
(TYROSINASE)		 3wky PROPHENOLOXIDASE B
(Marsupenaeus
japonicus) 		5 / 5 HIS A 199
HIS A 203
HIS A 361
VAL A 384
ALA A 387
 CUO  A 708 (-3.3A)
CUO  A 708 (-3.5A)
CUO  A 708 (-3.2A)
None
None
 0.76A 5i3bB-3wkyA:
9.9		 5i3bB-3wkyA:
17.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3B_B_HQEB303_1
(TYROSINASE)		 3wky PROPHENOLOXIDASE B
(Marsupenaeus
japonicus) 		4 / 5 HIS A 361
HIS A 397
HIS A 199
ALA A 387
 CUO  A 708 (-3.2A)
CUO  A 708 (-3.4A)
CUO  A 708 (-3.3A)
None
 0.97A 5i3bB-3wkyA:
9.9		 5i3bB-3wkyA:
17.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3B_B_HQEB303_1
(TYROSINASE)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		4 / 5 HIS A1293
HIS A1311
HIS A1428
ALA A1445
 CUO  A9004 (-3.2A)
CUO  A9004 (-3.4A)
CUO  A9004 (-3.4A)
None
 0.45A 5i3bB-4bedA:
21.2		 5i3bB-4bedA:
10.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3B_B_HQEB303_1
(TYROSINASE)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		4 / 5 HIS A1293
HIS A1320
HIS A1428
ALA A1445
 CUO  A9004 (-3.2A)
CUO  A9004 (-3.5A)
CUO  A9004 (-3.4A)
None
 1.22A 5i3bB-4bedA:
21.2		 5i3bB-4bedA:
10.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3B_B_HQEB303_1
(TYROSINASE)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		4 / 5 HIS A1428
HIS A1424
HIS A1293
ALA A1445
 CUO  A9004 (-3.4A)
CUO  A9004 (-3.0A)
CUO  A9004 (-3.2A)
None
 1.05A 5i3bB-4bedA:
21.2		 5i3bB-4bedA:
10.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3B_B_HQEB303_1
(TYROSINASE)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		4 / 5 HIS A1428
HIS A1455
HIS A1293
ALA A1445
 CUO  A9004 (-3.4A)
CUO  A9004 (-3.3A)
CUO  A9004 (-3.2A)
None
 0.92A 5i3bB-4bedA:
21.2		 5i3bB-4bedA:
10.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3B_B_HQEB303_1
(TYROSINASE)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		4 / 5 HIS B1705
HIS B1725
HIS B1851
ALA B1868
 CUO  B9005 (-3.2A)
CUO  B9005 (-3.1A)
CUO  B9005 (-3.2A)
None
 0.44A 5i3bB-4bedB:
23.8		 5i3bB-4bedB:
9.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3B_B_HQEB303_1
(TYROSINASE)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		4 / 5 HIS B1705
HIS B1734
HIS B1851
ALA B1868
 CUO  B9005 (-3.2A)
CUO  B9005 (-3.4A)
CUO  B9005 (-3.2A)
None
 1.39A 5i3bB-4bedB:
23.8		 5i3bB-4bedB:
9.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3B_B_HQEB303_1
(TYROSINASE)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		4 / 5 HIS B1851
HIS B1847
HIS B1705
ALA B1868
 CUO  B9005 (-3.2A)
CUO  B9005 (-3.2A)
CUO  B9005 (-3.2A)
None
 1.03A 5i3bB-4bedB:
23.8		 5i3bB-4bedB:
9.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3B_B_HQEB303_1
(TYROSINASE)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		4 / 5 HIS B1851
HIS B1878
HIS B1705
ALA B1868
 CUO  B9005 (-3.2A)
CUO  B9005 (-3.3A)
CUO  B9005 (-3.2A)
None
 1.06A 5i3bB-4bedB:
23.8		 5i3bB-4bedB:
9.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3B_B_HQEB303_1
(TYROSINASE)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		4 / 5 HIS B2122
HIS B2141
HIS B2264
ALA B2281
 CUO  B9006 (-3.2A)
CUO  B9006 (-3.1A)
CUO  B9006 (-3.2A)
None
 0.51A 5i3bB-4bedB:
23.8		 5i3bB-4bedB:
9.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3B_B_HQEB303_1
(TYROSINASE)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		4 / 5 HIS B2122
HIS B2150
HIS B2264
ALA B2281
 CUO  B9006 (-3.2A)
CUO  B9006 (-3.3A)
CUO  B9006 (-3.2A)
None
 1.32A 5i3bB-4bedB:
23.8		 5i3bB-4bedB:
9.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3B_B_HQEB303_1
(TYROSINASE)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		4 / 5 HIS B2264
HIS B2260
HIS B2122
ALA B2281
 CUO  B9006 (-3.2A)
CUO  B9006 (-3.2A)
CUO  B9006 (-3.2A)
None
 1.06A 5i3bB-4bedB:
23.8		 5i3bB-4bedB:
9.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3B_B_HQEB303_1
(TYROSINASE)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		4 / 5 HIS B2264
HIS B2291
HIS B2122
ALA B2281
 CUO  B9006 (-3.2A)
CUO  B9006 (-3.5A)
CUO  B9006 (-3.2A)
None
 0.93A 5i3bB-4bedB:
23.8		 5i3bB-4bedB:
9.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IY5_A_CUA601_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		3 / 3 HIS B2946
HIS B3106
HIS B2974
 CUO  B9008 (-3.1A)
CUO  B9008 (-3.3A)
CUO  B9008 (-2.9A)
 0.71A 5iy5A-4bedB:
undetectable		 5iy5A-4bedB:
14.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IY5_N_CUN602_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		3 / 3 HIS B2946
HIS B3106
HIS B2974
 CUO  B9008 (-3.1A)
CUO  B9008 (-3.3A)
CUO  B9008 (-2.9A)
 0.69A 5iy5N-4bedB:
undetectable		 5iy5N-4bedB:
14.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M8N_A_MMSA514_1
(5,6-DIHYDROXYINDOLE-
2-CARBOXYLIC ACID
OXIDASE)		 1js8 HEMOCYANIN
(Enteroctopus
dofleini) 		5 / 10 HIS A2543
HIS A2562
HIS A2671
ASN A2672
HIS A2675
 CUO  A 888 (-3.4A)
CUO  A 888 (-3.4A)
CUO  A 888 (-3.4A)
None
CUO  A 888 (-3.3A)
 0.41A 5m8nA-1js8A:
0.0		 5m8nA-1js8A:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M8N_A_MMSA514_1
(5,6-DIHYDROXYINDOLE-
2-CARBOXYLIC ACID
OXIDASE)		 3wky PROPHENOLOXIDASE B
(Marsupenaeus
japonicus) 		5 / 10 HIS A 199
HIS A 203
HIS A 357
ASN A 358
HIS A 361
 CUO  A 708 (-3.3A)
CUO  A 708 (-3.5A)
CUO  A 708 (-3.3A)
None
CUO  A 708 (-3.2A)
 0.65A 5m8nA-3wkyA:
8.9		 5m8nA-3wkyA:
20.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M8N_A_MMSA514_1
(5,6-DIHYDROXYINDOLE-
2-CARBOXYLIC ACID
OXIDASE)		 3wky PROPHENOLOXIDASE B
(Marsupenaeus
japonicus) 		5 / 10 HIS A 203
TYR A 208
HIS A 357
ASN A 358
HIS A 361
 CUO  A 708 (-3.5A)
None
CUO  A 708 (-3.3A)
None
CUO  A 708 (-3.2A)
 1.01A 5m8nA-3wkyA:
8.9		 5m8nA-3wkyA:
20.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M8N_A_MMSA514_1
(5,6-DIHYDROXYINDOLE-
2-CARBOXYLIC ACID
OXIDASE)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		5 / 10 HIS A  42
HIS A  60
HIS A 179
ASN A 180
HIS A 183
 CUO  A9001 (-3.4A)
CUO  A9001 (-3.1A)
CUO  A9001 (-3.4A)
None
CUO  A9001 (-3.4A)
 0.85A 5m8nA-4bedA:
7.3		 5m8nA-4bedA:
13.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M8N_A_MMSA514_1
(5,6-DIHYDROXYINDOLE-
2-CARBOXYLIC ACID
OXIDASE)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		5 / 10 HIS A 462
HIS A 482
HIS A 602
ASN A 603
HIS A 606
 CUO  A9002 (-3.2A)
CUO  A9002 (-3.4A)
CUO  A9002 (-3.4A)
None
CUO  A9002 (-3.3A)
 0.84A 5m8nA-4bedA:
7.3		 5m8nA-4bedA:
13.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M8N_A_MMSA514_1
(5,6-DIHYDROXYINDOLE-
2-CARBOXYLIC ACID
OXIDASE)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		5 / 10 HIS B2542
HIS B2561
HIS B2670
ASN B2671
HIS B2674
 CUO  B9007 (-3.3A)
CUO  B9007 (-3.3A)
CUO  B9007 (-3.4A)
None
CUO  B9007 (-3.4A)
 0.78A 5m8nA-4bedB:
20.6		 5m8nA-4bedB:
13.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M8N_A_MMSA514_1
(5,6-DIHYDROXYINDOLE-
2-CARBOXYLIC ACID
OXIDASE)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		6 / 10 HIS B2946
HIS B2965
HIS B3075
ASN B3076
HIS B3079
SER B3096
 CUO  B9008 (-3.1A)
CUO  B9008 (-3.2A)
CUO  B9008 (-2.8A)
None
CUO  B9008 (-3.5A)
CUO  B9008 ( 4.7A)
 0.57A 5m8nA-4bedB:
20.6		 5m8nA-4bedB:
13.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M8N_B_MMSB515_1
(5,6-DIHYDROXYINDOLE-
2-CARBOXYLIC ACID
OXIDASE)		 1js8 HEMOCYANIN
(Enteroctopus
dofleini) 		5 / 10 HIS A2543
HIS A2562
HIS A2671
ASN A2672
HIS A2675
 CUO  A 888 (-3.4A)
CUO  A 888 (-3.4A)
CUO  A 888 (-3.4A)
None
CUO  A 888 (-3.3A)
 0.48A 5m8nB-1js8A:
22.0		 5m8nB-1js8A:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M8N_B_MMSB515_1
(5,6-DIHYDROXYINDOLE-
2-CARBOXYLIC ACID
OXIDASE)		 3wky PROPHENOLOXIDASE B
(Marsupenaeus
japonicus) 		5 / 10 HIS A 199
HIS A 203
HIS A 357
ASN A 358
HIS A 361
 CUO  A 708 (-3.3A)
CUO  A 708 (-3.5A)
CUO  A 708 (-3.3A)
None
CUO  A 708 (-3.2A)
 0.68A 5m8nB-3wkyA:
7.3		 5m8nB-3wkyA:
20.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M8N_B_MMSB515_1
(5,6-DIHYDROXYINDOLE-
2-CARBOXYLIC ACID
OXIDASE)		 3wky PROPHENOLOXIDASE B
(Marsupenaeus
japonicus) 		5 / 10 HIS A 203
TYR A 208
HIS A 357
ASN A 358
HIS A 361
 CUO  A 708 (-3.5A)
None
CUO  A 708 (-3.3A)
None
CUO  A 708 (-3.2A)
 1.04A 5m8nB-3wkyA:
7.3		 5m8nB-3wkyA:
20.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M8N_B_MMSB515_1
(5,6-DIHYDROXYINDOLE-
2-CARBOXYLIC ACID
OXIDASE)		 3wky PROPHENOLOXIDASE B
(Marsupenaeus
japonicus) 		5 / 10 HIS A 357
HIS A 361
HIS A 199
HIS A 203
LEU A 204
 CUO  A 708 (-3.3A)
CUO  A 708 (-3.2A)
CUO  A 708 (-3.3A)
CUO  A 708 (-3.5A)
None
 0.95A 5m8nB-3wkyA:
7.3		 5m8nB-3wkyA:
20.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M8N_B_MMSB515_1
(5,6-DIHYDROXYINDOLE-
2-CARBOXYLIC ACID
OXIDASE)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		5 / 10 HIS A  42
HIS A  60
HIS A 179
ASN A 180
HIS A 183
 CUO  A9001 (-3.4A)
CUO  A9001 (-3.1A)
CUO  A9001 (-3.4A)
None
CUO  A9001 (-3.4A)
 0.99A 5m8nB-4bedA:
7.3		 5m8nB-4bedA:
13.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M8N_B_MMSB515_1
(5,6-DIHYDROXYINDOLE-
2-CARBOXYLIC ACID
OXIDASE)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		5 / 10 HIS A 462
HIS A 482
HIS A 602
ASN A 603
HIS A 606
 CUO  A9002 (-3.2A)
CUO  A9002 (-3.4A)
CUO  A9002 (-3.4A)
None
CUO  A9002 (-3.3A)
 0.97A 5m8nB-4bedA:
7.3		 5m8nB-4bedA:
13.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M8N_B_MMSB515_1
(5,6-DIHYDROXYINDOLE-
2-CARBOXYLIC ACID
OXIDASE)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		5 / 10 HIS B2542
HIS B2561
HIS B2670
ASN B2671
HIS B2674
 CUO  B9007 (-3.3A)
CUO  B9007 (-3.3A)
CUO  B9007 (-3.4A)
None
CUO  B9007 (-3.4A)
 0.90A 5m8nB-4bedB:
20.8		 5m8nB-4bedB:
13.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M8N_B_MMSB515_1
(5,6-DIHYDROXYINDOLE-
2-CARBOXYLIC ACID
OXIDASE)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		5 / 10 HIS B2946
HIS B2965
HIS B3075
HIS B3079
SER B3096
 CUO  B9008 (-3.1A)
CUO  B9008 (-3.2A)
CUO  B9008 (-2.8A)
CUO  B9008 (-3.5A)
CUO  B9008 ( 4.7A)
 0.59A 5m8nB-4bedB:
20.8		 5m8nB-4bedB:
13.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M8N_C_MMSC516_1
(5,6-DIHYDROXYINDOLE-
2-CARBOXYLIC ACID
OXIDASE)		 1js8 HEMOCYANIN
(Enteroctopus
dofleini) 		5 / 9 HIS A2543
HIS A2562
HIS A2671
ASN A2672
HIS A2675
 CUO  A 888 (-3.4A)
CUO  A 888 (-3.4A)
CUO  A 888 (-3.4A)
None
CUO  A 888 (-3.3A)
 0.47A 5m8nC-1js8A:
3.6		 5m8nC-1js8A:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M8N_C_MMSC516_1
(5,6-DIHYDROXYINDOLE-
2-CARBOXYLIC ACID
OXIDASE)		 3wky PROPHENOLOXIDASE B
(Marsupenaeus
japonicus) 		5 / 9 HIS A 199
HIS A 203
HIS A 357
ASN A 358
HIS A 361
 CUO  A 708 (-3.3A)
CUO  A 708 (-3.5A)
CUO  A 708 (-3.3A)
None
CUO  A 708 (-3.2A)
 0.65A 5m8nC-3wkyA:
8.8		 5m8nC-3wkyA:
20.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M8N_C_MMSC516_1
(5,6-DIHYDROXYINDOLE-
2-CARBOXYLIC ACID
OXIDASE)		 3wky PROPHENOLOXIDASE B
(Marsupenaeus
japonicus) 		5 / 9 HIS A 203
TYR A 208
HIS A 357
ASN A 358
HIS A 361
 CUO  A 708 (-3.5A)
None
CUO  A 708 (-3.3A)
None
CUO  A 708 (-3.2A)
 0.99A 5m8nC-3wkyA:
8.8		 5m8nC-3wkyA:
20.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M8N_C_MMSC516_1
(5,6-DIHYDROXYINDOLE-
2-CARBOXYLIC ACID
OXIDASE)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		5 / 9 HIS A  42
HIS A  60
HIS A 179
ASN A 180
HIS A 183
 CUO  A9001 (-3.4A)
CUO  A9001 (-3.1A)
CUO  A9001 (-3.4A)
None
CUO  A9001 (-3.4A)
 0.86A 5m8nC-4bedA:
17.2		 5m8nC-4bedA:
13.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M8N_C_MMSC516_1
(5,6-DIHYDROXYINDOLE-
2-CARBOXYLIC ACID
OXIDASE)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		5 / 9 HIS A 462
HIS A 482
HIS A 602
ASN A 603
HIS A 606
 CUO  A9002 (-3.2A)
CUO  A9002 (-3.4A)
CUO  A9002 (-3.4A)
None
CUO  A9002 (-3.3A)
 0.85A 5m8nC-4bedA:
17.2		 5m8nC-4bedA:
13.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M8N_C_MMSC516_1
(5,6-DIHYDROXYINDOLE-
2-CARBOXYLIC ACID
OXIDASE)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		5 / 9 HIS A 876
HIS A 896
HIS A1015
ASN A1016
HIS A1019
 CUO  A9003 (-3.3A)
CUO  A9003 (-3.4A)
CUO  A9003 (-3.1A)
None
CUO  A9003 (-3.4A)
 0.94A 5m8nC-4bedA:
17.2		 5m8nC-4bedA:
13.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M8N_C_MMSC516_1
(5,6-DIHYDROXYINDOLE-
2-CARBOXYLIC ACID
OXIDASE)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		5 / 9 HIS B1705
HIS B1725
HIS B1847
ASN B1848
HIS B1851
 CUO  B9005 (-3.2A)
CUO  B9005 (-3.1A)
CUO  B9005 (-3.2A)
None
CUO  B9005 (-3.2A)
 0.74A 5m8nC-4bedB:
21.7		 5m8nC-4bedB:
13.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M8N_C_MMSC516_1
(5,6-DIHYDROXYINDOLE-
2-CARBOXYLIC ACID
OXIDASE)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		5 / 9 HIS B2122
HIS B2141
HIS B2260
ASN B2261
HIS B2264
 CUO  B9006 (-3.2A)
CUO  B9006 (-3.1A)
CUO  B9006 (-3.2A)
None
CUO  B9006 (-3.2A)
 0.78A 5m8nC-4bedB:
21.7		 5m8nC-4bedB:
13.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M8N_C_MMSC516_1
(5,6-DIHYDROXYINDOLE-
2-CARBOXYLIC ACID
OXIDASE)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		5 / 9 HIS B2542
HIS B2561
HIS B2670
ASN B2671
HIS B2674
 CUO  B9007 (-3.3A)
CUO  B9007 (-3.3A)
CUO  B9007 (-3.4A)
None
CUO  B9007 (-3.4A)
 0.80A 5m8nC-4bedB:
21.7		 5m8nC-4bedB:
13.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M8N_C_MMSC516_1
(5,6-DIHYDROXYINDOLE-
2-CARBOXYLIC ACID
OXIDASE)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		6 / 9 HIS B2946
HIS B2965
HIS B3075
ASN B3076
HIS B3079
SER B3096
 CUO  B9008 (-3.1A)
CUO  B9008 (-3.2A)
CUO  B9008 (-2.8A)
None
CUO  B9008 (-3.5A)
CUO  B9008 ( 4.7A)
 0.65A 5m8nC-4bedB:
21.7		 5m8nC-4bedB:
13.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M8N_C_MMSC516_1
(5,6-DIHYDROXYINDOLE-
2-CARBOXYLIC ACID
OXIDASE)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		5 / 9 HIS B2974
HIS B3075
ASN B3076
HIS B3079
SER B3096
 CUO  B9008 (-2.9A)
CUO  B9008 (-2.8A)
None
CUO  B9008 (-3.5A)
CUO  B9008 ( 4.7A)
 1.29A 5m8nC-4bedB:
21.7		 5m8nC-4bedB:
13.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M8N_D_MMSD515_1
(5,6-DIHYDROXYINDOLE-
2-CARBOXYLIC ACID
OXIDASE)		 3wky PROPHENOLOXIDASE B
(Marsupenaeus
japonicus) 		5 / 9 HIS A 203
TYR A 208
HIS A 357
ASN A 358
HIS A 361
 CUO  A 708 (-3.5A)
None
CUO  A 708 (-3.3A)
None
CUO  A 708 (-3.2A)
 1.05A 5m8nD-3wkyA:
8.5		 5m8nD-3wkyA:
20.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M8N_D_MMSD515_1
(5,6-DIHYDROXYINDOLE-
2-CARBOXYLIC ACID
OXIDASE)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		5 / 9 HIS B2974
HIS B3075
ASN B3076
HIS B3079
SER B3096
 CUO  B9008 (-2.9A)
CUO  B9008 (-2.8A)
None
CUO  B9008 (-3.5A)
CUO  B9008 ( 4.7A)
 1.28A 5m8nD-4bedB:
19.1		 5m8nD-4bedB:
13.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M8R_A_MMSA511_1
(5,6-DIHYDROXYINDOLE-
2-CARBOXYLIC ACID
OXIDASE)		 1js8 HEMOCYANIN
(Enteroctopus
dofleini) 		4 / 7 HIS A2562
HIS A2671
ASN A2672
HIS A2675
 CUO  A 888 (-3.4A)
CUO  A 888 (-3.4A)
None
CUO  A 888 (-3.3A)
 0.44A 5m8rA-1js8A:
22.1		 5m8rA-1js8A:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M8R_A_MMSA511_1
(5,6-DIHYDROXYINDOLE-
2-CARBOXYLIC ACID
OXIDASE)		 3wky PROPHENOLOXIDASE B
(Marsupenaeus
japonicus) 		5 / 7 HIS A 203
HIS A 357
ASN A 358
HIS A 361
VAL A 384
 CUO  A 708 (-3.5A)
CUO  A 708 (-3.3A)
None
CUO  A 708 (-3.2A)
None
 0.69A 5m8rA-3wkyA:
8.4		 5m8rA-3wkyA:
21.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M8R_A_MMSA511_1
(5,6-DIHYDROXYINDOLE-
2-CARBOXYLIC ACID
OXIDASE)		 3wky PROPHENOLOXIDASE B
(Marsupenaeus
japonicus) 		4 / 7 HIS A 361
HIS A 199
HIS A 203
LEU A 204
 CUO  A 708 (-3.2A)
CUO  A 708 (-3.3A)
CUO  A 708 (-3.5A)
None
 1.01A 5m8rA-3wkyA:
8.4		 5m8rA-3wkyA:
21.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M8R_A_MMSA511_1
(5,6-DIHYDROXYINDOLE-
2-CARBOXYLIC ACID
OXIDASE)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		4 / 7 HIS A  60
HIS A 179
ASN A 180
HIS A 183
 CUO  A9001 (-3.1A)
CUO  A9001 (-3.4A)
None
CUO  A9001 (-3.4A)
 1.00A 5m8rA-4bedA:
20.5		 5m8rA-4bedA:
13.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M8R_A_MMSA511_1
(5,6-DIHYDROXYINDOLE-
2-CARBOXYLIC ACID
OXIDASE)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		4 / 7 HIS A 482
HIS A 602
ASN A 603
HIS A 606
 CUO  A9002 (-3.4A)
CUO  A9002 (-3.4A)
None
CUO  A9002 (-3.3A)
 0.96A 5m8rA-4bedA:
20.5		 5m8rA-4bedA:
13.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M8R_A_MMSA511_1
(5,6-DIHYDROXYINDOLE-
2-CARBOXYLIC ACID
OXIDASE)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		4 / 7 HIS A 896
HIS A1015
ASN A1016
HIS A1019
 CUO  A9003 (-3.4A)
CUO  A9003 (-3.1A)
None
CUO  A9003 (-3.4A)
 1.02A 5m8rA-4bedA:
20.5		 5m8rA-4bedA:
13.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M8R_A_MMSA511_1
(5,6-DIHYDROXYINDOLE-
2-CARBOXYLIC ACID
OXIDASE)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		4 / 7 HIS B1725
HIS B1847
ASN B1848
HIS B1851
 CUO  B9005 (-3.1A)
CUO  B9005 (-3.2A)
None
CUO  B9005 (-3.2A)
 0.84A 5m8rA-4bedB:
19.5		 5m8rA-4bedB:
13.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M8R_A_MMSA511_1
(5,6-DIHYDROXYINDOLE-
2-CARBOXYLIC ACID
OXIDASE)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		4 / 7 HIS B2141
HIS B2260
ASN B2261
HIS B2264
 CUO  B9006 (-3.1A)
CUO  B9006 (-3.2A)
None
CUO  B9006 (-3.2A)
 0.89A 5m8rA-4bedB:
19.5		 5m8rA-4bedB:
13.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M8R_A_MMSA511_1
(5,6-DIHYDROXYINDOLE-
2-CARBOXYLIC ACID
OXIDASE)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		4 / 7 HIS B2561
HIS B2670
ASN B2671
HIS B2674
 CUO  B9007 (-3.3A)
CUO  B9007 (-3.4A)
None
CUO  B9007 (-3.4A)
 0.88A 5m8rA-4bedB:
19.5		 5m8rA-4bedB:
13.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M8R_A_MMSA511_1
(5,6-DIHYDROXYINDOLE-
2-CARBOXYLIC ACID
OXIDASE)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		4 / 7 HIS B2965
HIS B3075
HIS B3079
SER B3096
 CUO  B9008 (-3.2A)
CUO  B9008 (-2.8A)
CUO  B9008 (-3.5A)
CUO  B9008 ( 4.7A)
 0.61A 5m8rA-4bedB:
19.5		 5m8rA-4bedB:
13.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M8R_A_MMSA511_1
(5,6-DIHYDROXYINDOLE-
2-CARBOXYLIC ACID
OXIDASE)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		5 / 7 HIS B2974
HIS B3075
ASN B3076
HIS B3079
SER B3096
 CUO  B9008 (-2.9A)
CUO  B9008 (-2.8A)
None
CUO  B9008 (-3.5A)
CUO  B9008 ( 4.7A)
 1.28A 5m8rA-4bedB:
19.5		 5m8rA-4bedB:
13.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M8R_B_MMSB514_1
(5,6-DIHYDROXYINDOLE-
2-CARBOXYLIC ACID
OXIDASE)		 1js8 HEMOCYANIN
(Enteroctopus
dofleini) 		4 / 8 HIS A2562
HIS A2671
ASN A2672
HIS A2675
 CUO  A 888 (-3.4A)
CUO  A 888 (-3.4A)
None
CUO  A 888 (-3.3A)
 0.40A 5m8rB-1js8A:
21.9		 5m8rB-1js8A:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M8R_B_MMSB514_1
(5,6-DIHYDROXYINDOLE-
2-CARBOXYLIC ACID
OXIDASE)		 3wky PROPHENOLOXIDASE B
(Marsupenaeus
japonicus) 		5 / 8 HIS A 203
HIS A 357
ASN A 358
HIS A 361
VAL A 384
 CUO  A 708 (-3.5A)
CUO  A 708 (-3.3A)
None
CUO  A 708 (-3.2A)
None
 0.70A 5m8rB-3wkyA:
8.8		 5m8rB-3wkyA:
21.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M8R_B_MMSB514_1
(5,6-DIHYDROXYINDOLE-
2-CARBOXYLIC ACID
OXIDASE)		 3wky PROPHENOLOXIDASE B
(Marsupenaeus
japonicus) 		4 / 8 HIS A 361
HIS A 199
HIS A 203
LEU A 204
 CUO  A 708 (-3.2A)
CUO  A 708 (-3.3A)
CUO  A 708 (-3.5A)
None
 1.01A 5m8rB-3wkyA:
8.8		 5m8rB-3wkyA:
21.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M8R_B_MMSB514_1
(5,6-DIHYDROXYINDOLE-
2-CARBOXYLIC ACID
OXIDASE)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		4 / 8 HIS A  60
HIS A 179
ASN A 180
HIS A 183
 CUO  A9001 (-3.1A)
CUO  A9001 (-3.4A)
None
CUO  A9001 (-3.4A)
 0.98A 5m8rB-4bedA:
7.2		 5m8rB-4bedA:
13.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M8R_B_MMSB514_1
(5,6-DIHYDROXYINDOLE-
2-CARBOXYLIC ACID
OXIDASE)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		4 / 8 HIS A 482
HIS A 602
ASN A 603
HIS A 606
 CUO  A9002 (-3.4A)
CUO  A9002 (-3.4A)
None
CUO  A9002 (-3.3A)
 0.95A 5m8rB-4bedA:
7.2		 5m8rB-4bedA:
13.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M8R_B_MMSB514_1
(5,6-DIHYDROXYINDOLE-
2-CARBOXYLIC ACID
OXIDASE)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		4 / 8 HIS B1725
HIS B1847
ASN B1848
HIS B1851
 CUO  B9005 (-3.1A)
CUO  B9005 (-3.2A)
None
CUO  B9005 (-3.2A)
 0.84A 5m8rB-4bedB:
20.8		 5m8rB-4bedB:
13.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M8R_B_MMSB514_1
(5,6-DIHYDROXYINDOLE-
2-CARBOXYLIC ACID
OXIDASE)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		4 / 8 HIS B2561
HIS B2670
ASN B2671
HIS B2674
 CUO  B9007 (-3.3A)
CUO  B9007 (-3.4A)
None
CUO  B9007 (-3.4A)
 0.87A 5m8rB-4bedB:
20.8		 5m8rB-4bedB:
13.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M8R_B_MMSB514_1
(5,6-DIHYDROXYINDOLE-
2-CARBOXYLIC ACID
OXIDASE)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		5 / 8 HIS B2974
HIS B3075
ASN B3076
HIS B3079
SER B3096
 CUO  B9008 (-2.9A)
CUO  B9008 (-2.8A)
None
CUO  B9008 (-3.5A)
CUO  B9008 ( 4.7A)
 1.27A 5m8rB-4bedB:
20.8		 5m8rB-4bedB:
13.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M8R_C_MMSC516_1
(5,6-DIHYDROXYINDOLE-
2-CARBOXYLIC ACID
OXIDASE)		 1js8 HEMOCYANIN
(Enteroctopus
dofleini) 		4 / 8 HIS A2562
HIS A2671
ASN A2672
HIS A2675
 CUO  A 888 (-3.4A)
CUO  A 888 (-3.4A)
None
CUO  A 888 (-3.3A)
 0.34A 5m8rC-1js8A:
22.1		 5m8rC-1js8A:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M8R_C_MMSC516_1
(5,6-DIHYDROXYINDOLE-
2-CARBOXYLIC ACID
OXIDASE)		 3wky PROPHENOLOXIDASE B
(Marsupenaeus
japonicus) 		6 / 8 HIS A 203
HIS A 357
ASN A 358
HIS A 361
GLY A 382
VAL A 384
 CUO  A 708 (-3.5A)
CUO  A 708 (-3.3A)
None
CUO  A 708 (-3.2A)
None
None
 0.71A 5m8rC-3wkyA:
8.6		 5m8rC-3wkyA:
21.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M8R_C_MMSC516_1
(5,6-DIHYDROXYINDOLE-
2-CARBOXYLIC ACID
OXIDASE)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		4 / 8 HIS B1725
ASN B1848
HIS B1851
GLY B1863
 CUO  B9005 (-3.1A)
None
CUO  B9005 (-3.2A)
None
 0.41A 5m8rC-4bedB:
19.5		 5m8rC-4bedB:
13.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M8R_C_MMSC516_1
(5,6-DIHYDROXYINDOLE-
2-CARBOXYLIC ACID
OXIDASE)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		4 / 8 HIS B1725
HIS B1847
HIS B1851
GLY B1863
 CUO  B9005 (-3.1A)
CUO  B9005 (-3.2A)
CUO  B9005 (-3.2A)
None
 0.85A 5m8rC-4bedB:
19.5		 5m8rC-4bedB:
13.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M8R_C_MMSC516_1
(5,6-DIHYDROXYINDOLE-
2-CARBOXYLIC ACID
OXIDASE)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		4 / 8 HIS B3075
ASN B3076
HIS B3079
SER B3096
 CUO  B9008 (-2.8A)
None
CUO  B9008 (-3.5A)
CUO  B9008 ( 4.7A)
 0.35A 5m8rC-4bedB:
19.5		 5m8rC-4bedB:
13.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M8R_C_MMSC516_1
(5,6-DIHYDROXYINDOLE-
2-CARBOXYLIC ACID
OXIDASE)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		4 / 8 HIS B3106
HIS B2965
GLY B2947
SER B3096
 CUO  B9008 (-3.3A)
CUO  B9008 (-3.2A)
None
CUO  B9008 ( 4.7A)
 0.87A 5m8rC-4bedB:
19.5		 5m8rC-4bedB:
13.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M8R_D_MMSD509_1
(5,6-DIHYDROXYINDOLE-
2-CARBOXYLIC ACID
OXIDASE)		 1js8 HEMOCYANIN
(Enteroctopus
dofleini) 		4 / 8 HIS A2562
HIS A2671
ASN A2672
HIS A2675
 CUO  A 888 (-3.4A)
CUO  A 888 (-3.4A)
None
CUO  A 888 (-3.3A)
 0.38A 5m8rD-1js8A:
22.1		 5m8rD-1js8A:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M8R_D_MMSD509_1
(5,6-DIHYDROXYINDOLE-
2-CARBOXYLIC ACID
OXIDASE)		 3wky PROPHENOLOXIDASE B
(Marsupenaeus
japonicus) 		5 / 8 HIS A 203
HIS A 357
ASN A 358
HIS A 361
VAL A 384
 CUO  A 708 (-3.5A)
CUO  A 708 (-3.3A)
None
CUO  A 708 (-3.2A)
None
 0.71A 5m8rD-3wkyA:
8.6		 5m8rD-3wkyA:
21.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M8R_D_MMSD509_1
(5,6-DIHYDROXYINDOLE-
2-CARBOXYLIC ACID
OXIDASE)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		4 / 8 HIS A  60
HIS A 179
ASN A 180
HIS A 183
 CUO  A9001 (-3.1A)
CUO  A9001 (-3.4A)
None
CUO  A9001 (-3.4A)
 0.96A 5m8rD-4bedA:
7.3		 5m8rD-4bedA:
13.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M8R_D_MMSD509_1
(5,6-DIHYDROXYINDOLE-
2-CARBOXYLIC ACID
OXIDASE)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		4 / 8 HIS A 482
HIS A 602
ASN A 603
HIS A 606
 CUO  A9002 (-3.4A)
CUO  A9002 (-3.4A)
None
CUO  A9002 (-3.3A)
 0.93A 5m8rD-4bedA:
7.3		 5m8rD-4bedA:
13.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M8R_D_MMSD509_1
(5,6-DIHYDROXYINDOLE-
2-CARBOXYLIC ACID
OXIDASE)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		4 / 8 HIS B1725
HIS B1847
ASN B1848
HIS B1851
 CUO  B9005 (-3.1A)
CUO  B9005 (-3.2A)
None
CUO  B9005 (-3.2A)
 0.81A 5m8rD-4bedB:
19.5		 5m8rD-4bedB:
13.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M8R_D_MMSD509_1
(5,6-DIHYDROXYINDOLE-
2-CARBOXYLIC ACID
OXIDASE)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		4 / 8 HIS B2561
HIS B2670
ASN B2671
HIS B2674
 CUO  B9007 (-3.3A)
CUO  B9007 (-3.4A)
None
CUO  B9007 (-3.4A)
 0.83A 5m8rD-4bedB:
19.5		 5m8rD-4bedB:
13.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M8R_D_MMSD509_1
(5,6-DIHYDROXYINDOLE-
2-CARBOXYLIC ACID
OXIDASE)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		5 / 8 HIS B2974
HIS B3075
ASN B3076
HIS B3079
SER B3096
 CUO  B9008 (-2.9A)
CUO  B9008 (-2.8A)
None
CUO  B9008 (-3.5A)
CUO  B9008 ( 4.7A)
 1.29A 5m8rD-4bedB:
19.5		 5m8rD-4bedB:
13.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MEJ_A_CUA501_0
(LACCASE 2)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		5 / 5 HIS B3106
HIS B3075
HIS B2946
HIS B2974
HIS B2965
 CUO  B9008 (-3.3A)
CUO  B9008 (-2.8A)
CUO  B9008 (-3.1A)
CUO  B9008 (-2.9A)
CUO  B9008 (-3.2A)
 1.30A 5mejA-4bedB:
3.7		 5mejA-4bedB:
14.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MEW_A_CUA501_0
(LACCASE 2)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		5 / 5 HIS B3106
HIS B3075
HIS B2946
HIS B2974
HIS B2965
 CUO  B9008 (-3.3A)
CUO  B9008 (-2.8A)
CUO  B9008 (-3.1A)
CUO  B9008 (-2.9A)
CUO  B9008 (-3.2A)
 1.31A 5mewA-4bedB:
undetectable		 5mewA-4bedB:
14.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHU_A_CUA501_0
(LACCASE 2)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		5 / 5 HIS B3106
HIS B3075
HIS B2946
HIS B2974
HIS B2965
 CUO  B9008 (-3.3A)
CUO  B9008 (-2.8A)
CUO  B9008 (-3.1A)
CUO  B9008 (-2.9A)
CUO  B9008 (-3.2A)
 1.31A 5mhuA-4bedB:
undetectable		 5mhuA-4bedB:
14.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHV_A_CUA501_0
(LACCASE 2)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		5 / 5 HIS B3106
HIS B3075
HIS B2946
HIS B2974
HIS B2965
 CUO  B9008 (-3.3A)
CUO  B9008 (-2.8A)
CUO  B9008 (-3.1A)
CUO  B9008 (-2.9A)
CUO  B9008 (-3.2A)
 1.31A 5mhvA-4bedB:
3.6		 5mhvA-4bedB:
14.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHW_A_CUA601_0
(LACCASE 2)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		4 / 4 HIS A  60
HIS A 210
HIS A  69
HIS A  42
 CUO  A9001 (-3.1A)
CUO  A9001 (-3.3A)
CUO  A9001 (-3.1A)
CUO  A9001 (-3.4A)
 0.93A 5mhwA-4bedA:
undetectable		 5mhwA-4bedA:
16.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHW_A_CUA601_0
(LACCASE 2)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		4 / 4 HIS A 482
HIS A 633
HIS A 491
HIS A 462
 CUO  A9002 (-3.4A)
CUO  A9002 (-3.3A)
CUO  A9002 (-3.4A)
CUO  A9002 (-3.2A)
 0.97A 5mhwA-4bedA:
undetectable		 5mhwA-4bedA:
16.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHW_A_CUA601_0
(LACCASE 2)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		4 / 4 HIS A 896
HIS A1046
HIS A 905
HIS A 876
 CUO  A9003 (-3.4A)
CUO  A9003 (-3.2A)
CUO  A9003 (-3.5A)
CUO  A9003 (-3.3A)
 0.95A 5mhwA-4bedA:
undetectable		 5mhwA-4bedA:
16.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHW_A_CUA601_0
(LACCASE 2)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		4 / 4 HIS A1019
HIS A 905
HIS A 876
HIS A1046
 CUO  A9003 (-3.4A)
CUO  A9003 (-3.5A)
CUO  A9003 (-3.3A)
CUO  A9003 (-3.2A)
 0.99A 5mhwA-4bedA:
undetectable		 5mhwA-4bedA:
16.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHW_A_CUA601_0
(LACCASE 2)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		4 / 4 HIS A1311
HIS A1455
HIS A1320
HIS A1293
 CUO  A9004 (-3.4A)
CUO  A9004 (-3.3A)
CUO  A9004 (-3.5A)
CUO  A9004 (-3.2A)
 0.93A 5mhwA-4bedA:
undetectable		 5mhwA-4bedA:
16.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHW_A_CUA601_0
(LACCASE 2)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		4 / 4 HIS A1428
HIS A1320
HIS A1293
HIS A1455
 CUO  A9004 (-3.4A)
CUO  A9004 (-3.5A)
CUO  A9004 (-3.2A)
CUO  A9004 (-3.3A)
 0.97A 5mhwA-4bedA:
undetectable		 5mhwA-4bedA:
16.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHW_A_CUA601_0
(LACCASE 2)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		4 / 4 HIS B1725
HIS B1878
HIS B1734
HIS B1705
 CUO  B9005 (-3.1A)
CUO  B9005 (-3.3A)
CUO  B9005 (-3.4A)
CUO  B9005 (-3.2A)
 1.02A 5mhwA-4bedB:
3.6		 5mhwA-4bedB:
15.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHW_A_CUA601_0
(LACCASE 2)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		4 / 4 HIS B2561
HIS B2701
HIS B2570
HIS B2542
 CUO  B9007 (-3.3A)
CUO  B9007 (-3.1A)
CUO  B9007 (-3.3A)
CUO  B9007 (-3.3A)
 0.99A 5mhwA-4bedB:
3.6		 5mhwA-4bedB:
15.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHX_A_CUA601_0
(LACCASE 2)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		4 / 4 HIS A  60
HIS A 210
HIS A  69
HIS A  42
 CUO  A9001 (-3.1A)
CUO  A9001 (-3.3A)
CUO  A9001 (-3.1A)
CUO  A9001 (-3.4A)
 0.93A 5mhxA-4bedA:
undetectable		 5mhxA-4bedA:
16.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHX_A_CUA601_0
(LACCASE 2)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		4 / 4 HIS A 482
HIS A 633
HIS A 491
HIS A 462
 CUO  A9002 (-3.4A)
CUO  A9002 (-3.3A)
CUO  A9002 (-3.4A)
CUO  A9002 (-3.2A)
 0.97A 5mhxA-4bedA:
undetectable		 5mhxA-4bedA:
16.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHX_A_CUA601_0
(LACCASE 2)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		4 / 4 HIS A 896
HIS A1046
HIS A 905
HIS A 876
 CUO  A9003 (-3.4A)
CUO  A9003 (-3.2A)
CUO  A9003 (-3.5A)
CUO  A9003 (-3.3A)
 0.94A 5mhxA-4bedA:
undetectable		 5mhxA-4bedA:
16.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHX_A_CUA601_0
(LACCASE 2)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		4 / 4 HIS A1019
HIS A 905
HIS A 876
HIS A1046
 CUO  A9003 (-3.4A)
CUO  A9003 (-3.5A)
CUO  A9003 (-3.3A)
CUO  A9003 (-3.2A)
 0.99A 5mhxA-4bedA:
undetectable		 5mhxA-4bedA:
16.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHX_A_CUA601_0
(LACCASE 2)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		4 / 4 HIS A1311
HIS A1455
HIS A1320
HIS A1293
 CUO  A9004 (-3.4A)
CUO  A9004 (-3.3A)
CUO  A9004 (-3.5A)
CUO  A9004 (-3.2A)
 0.92A 5mhxA-4bedA:
undetectable		 5mhxA-4bedA:
16.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHX_A_CUA601_0
(LACCASE 2)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		4 / 4 HIS A1428
HIS A1320
HIS A1293
HIS A1455
 CUO  A9004 (-3.4A)
CUO  A9004 (-3.5A)
CUO  A9004 (-3.2A)
CUO  A9004 (-3.3A)
 0.97A 5mhxA-4bedA:
undetectable		 5mhxA-4bedA:
16.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHX_A_CUA601_0
(LACCASE 2)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		4 / 4 HIS B1725
HIS B1878
HIS B1734
HIS B1705
 CUO  B9005 (-3.1A)
CUO  B9005 (-3.3A)
CUO  B9005 (-3.4A)
CUO  B9005 (-3.2A)
 1.01A 5mhxA-4bedB:
3.6		 5mhxA-4bedB:
15.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHX_A_CUA601_0
(LACCASE 2)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		4 / 4 HIS B2561
HIS B2701
HIS B2570
HIS B2542
 CUO  B9007 (-3.3A)
CUO  B9007 (-3.1A)
CUO  B9007 (-3.3A)
CUO  B9007 (-3.3A)
 0.99A 5mhxA-4bedB:
3.6		 5mhxA-4bedB:
15.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHY_A_CUA601_0
(LACCASE 2)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		4 / 4 HIS A  60
HIS A 210
HIS A  69
HIS A  42
 CUO  A9001 (-3.1A)
CUO  A9001 (-3.3A)
CUO  A9001 (-3.1A)
CUO  A9001 (-3.4A)
 0.93A 5mhyA-4bedA:
undetectable		 5mhyA-4bedA:
16.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHY_A_CUA601_0
(LACCASE 2)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		4 / 4 HIS A 482
HIS A 633
HIS A 491
HIS A 462
 CUO  A9002 (-3.4A)
CUO  A9002 (-3.3A)
CUO  A9002 (-3.4A)
CUO  A9002 (-3.2A)
 0.97A 5mhyA-4bedA:
undetectable		 5mhyA-4bedA:
16.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHY_A_CUA601_0
(LACCASE 2)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		4 / 4 HIS A 896
HIS A1046
HIS A 905
HIS A 876
 CUO  A9003 (-3.4A)
CUO  A9003 (-3.2A)
CUO  A9003 (-3.5A)
CUO  A9003 (-3.3A)
 0.94A 5mhyA-4bedA:
undetectable		 5mhyA-4bedA:
16.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHY_A_CUA601_0
(LACCASE 2)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		4 / 4 HIS A1019
HIS A 905
HIS A 876
HIS A1046
 CUO  A9003 (-3.4A)
CUO  A9003 (-3.5A)
CUO  A9003 (-3.3A)
CUO  A9003 (-3.2A)
 0.99A 5mhyA-4bedA:
undetectable		 5mhyA-4bedA:
16.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHY_A_CUA601_0
(LACCASE 2)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		4 / 4 HIS A1311
HIS A1455
HIS A1320
HIS A1293
 CUO  A9004 (-3.4A)
CUO  A9004 (-3.3A)
CUO  A9004 (-3.5A)
CUO  A9004 (-3.2A)
 0.93A 5mhyA-4bedA:
undetectable		 5mhyA-4bedA:
16.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHY_A_CUA601_0
(LACCASE 2)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		4 / 4 HIS A1428
HIS A1320
HIS A1293
HIS A1455
 CUO  A9004 (-3.4A)
CUO  A9004 (-3.5A)
CUO  A9004 (-3.2A)
CUO  A9004 (-3.3A)
 0.96A 5mhyA-4bedA:
undetectable		 5mhyA-4bedA:
16.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHY_A_CUA601_0
(LACCASE 2)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		4 / 4 HIS B1725
HIS B1878
HIS B1734
HIS B1705
 CUO  B9005 (-3.1A)
CUO  B9005 (-3.3A)
CUO  B9005 (-3.4A)
CUO  B9005 (-3.2A)
 1.01A 5mhyA-4bedB:
3.6		 5mhyA-4bedB:
15.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHY_A_CUA601_0
(LACCASE 2)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		4 / 4 HIS B2561
HIS B2701
HIS B2570
HIS B2542
 CUO  B9007 (-3.3A)
CUO  B9007 (-3.1A)
CUO  B9007 (-3.3A)
CUO  B9007 (-3.3A)
 0.99A 5mhyA-4bedB:
3.6		 5mhyA-4bedB:
15.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHZ_A_CUA601_0
(LACCASE 2)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		4 / 4 HIS A  60
HIS A 210
HIS A  69
HIS A  42
 CUO  A9001 (-3.1A)
CUO  A9001 (-3.3A)
CUO  A9001 (-3.1A)
CUO  A9001 (-3.4A)
 0.93A 5mhzA-4bedA:
undetectable		 5mhzA-4bedA:
16.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHZ_A_CUA601_0
(LACCASE 2)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		4 / 4 HIS A 482
HIS A 633
HIS A 491
HIS A 462
 CUO  A9002 (-3.4A)
CUO  A9002 (-3.3A)
CUO  A9002 (-3.4A)
CUO  A9002 (-3.2A)
 0.97A 5mhzA-4bedA:
undetectable		 5mhzA-4bedA:
16.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHZ_A_CUA601_0
(LACCASE 2)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		4 / 4 HIS A 896
HIS A1046
HIS A 905
HIS A 876
 CUO  A9003 (-3.4A)
CUO  A9003 (-3.2A)
CUO  A9003 (-3.5A)
CUO  A9003 (-3.3A)
 0.94A 5mhzA-4bedA:
undetectable		 5mhzA-4bedA:
16.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHZ_A_CUA601_0
(LACCASE 2)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		4 / 4 HIS A1019
HIS A 905
HIS A 876
HIS A1046
 CUO  A9003 (-3.4A)
CUO  A9003 (-3.5A)
CUO  A9003 (-3.3A)
CUO  A9003 (-3.2A)
 0.98A 5mhzA-4bedA:
undetectable		 5mhzA-4bedA:
16.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHZ_A_CUA601_0
(LACCASE 2)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		4 / 4 HIS A1311
HIS A1455
HIS A1320
HIS A1293
 CUO  A9004 (-3.4A)
CUO  A9004 (-3.3A)
CUO  A9004 (-3.5A)
CUO  A9004 (-3.2A)
 0.93A 5mhzA-4bedA:
undetectable		 5mhzA-4bedA:
16.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHZ_A_CUA601_0
(LACCASE 2)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		4 / 4 HIS A1428
HIS A1320
HIS A1293
HIS A1455
 CUO  A9004 (-3.4A)
CUO  A9004 (-3.5A)
CUO  A9004 (-3.2A)
CUO  A9004 (-3.3A)
 0.96A 5mhzA-4bedA:
undetectable		 5mhzA-4bedA:
16.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHZ_A_CUA601_0
(LACCASE 2)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		4 / 4 HIS B1725
HIS B1878
HIS B1734
HIS B1705
 CUO  B9005 (-3.1A)
CUO  B9005 (-3.3A)
CUO  B9005 (-3.4A)
CUO  B9005 (-3.2A)
 1.02A 5mhzA-4bedB:
3.6		 5mhzA-4bedB:
15.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHZ_A_CUA601_0
(LACCASE 2)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		4 / 4 HIS B2561
HIS B2701
HIS B2570
HIS B2542
 CUO  B9007 (-3.3A)
CUO  B9007 (-3.1A)
CUO  B9007 (-3.3A)
CUO  B9007 (-3.3A)
 0.99A 5mhzA-4bedB:
3.6		 5mhzA-4bedB:
15.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MI1_A_CUA601_0
(LACCASE 2)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		4 / 4 HIS A  60
HIS A 210
HIS A  69
HIS A  42
 CUO  A9001 (-3.1A)
CUO  A9001 (-3.3A)
CUO  A9001 (-3.1A)
CUO  A9001 (-3.4A)
 0.93A 5mi1A-4bedA:
undetectable		 5mi1A-4bedA:
16.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MI1_A_CUA601_0
(LACCASE 2)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		4 / 4 HIS A 482
HIS A 633
HIS A 491
HIS A 462
 CUO  A9002 (-3.4A)
CUO  A9002 (-3.3A)
CUO  A9002 (-3.4A)
CUO  A9002 (-3.2A)
 0.97A 5mi1A-4bedA:
undetectable		 5mi1A-4bedA:
16.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MI1_A_CUA601_0
(LACCASE 2)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		4 / 4 HIS A 896
HIS A1046
HIS A 905
HIS A 876
 CUO  A9003 (-3.4A)
CUO  A9003 (-3.2A)
CUO  A9003 (-3.5A)
CUO  A9003 (-3.3A)
 0.94A 5mi1A-4bedA:
undetectable		 5mi1A-4bedA:
16.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MI1_A_CUA601_0
(LACCASE 2)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		4 / 4 HIS A1019
HIS A 905
HIS A 876
HIS A1046
 CUO  A9003 (-3.4A)
CUO  A9003 (-3.5A)
CUO  A9003 (-3.3A)
CUO  A9003 (-3.2A)
 0.98A 5mi1A-4bedA:
undetectable		 5mi1A-4bedA:
16.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MI1_A_CUA601_0
(LACCASE 2)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		4 / 4 HIS A1311
HIS A1455
HIS A1320
HIS A1293
 CUO  A9004 (-3.4A)
CUO  A9004 (-3.3A)
CUO  A9004 (-3.5A)
CUO  A9004 (-3.2A)
 0.92A 5mi1A-4bedA:
undetectable		 5mi1A-4bedA:
16.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MI1_A_CUA601_0
(LACCASE 2)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		4 / 4 HIS A1428
HIS A1320
HIS A1293
HIS A1455
 CUO  A9004 (-3.4A)
CUO  A9004 (-3.5A)
CUO  A9004 (-3.2A)
CUO  A9004 (-3.3A)
 0.96A 5mi1A-4bedA:
undetectable		 5mi1A-4bedA:
16.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MI1_A_CUA601_0
(LACCASE 2)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		4 / 4 HIS B1725
HIS B1878
HIS B1734
HIS B1705
 CUO  B9005 (-3.1A)
CUO  B9005 (-3.3A)
CUO  B9005 (-3.4A)
CUO  B9005 (-3.2A)
 1.01A 5mi1A-4bedB:
undetectable		 5mi1A-4bedB:
15.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MI1_A_CUA601_0
(LACCASE 2)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		4 / 4 HIS B2561
HIS B2701
HIS B2570
HIS B2542
 CUO  B9007 (-3.3A)
CUO  B9007 (-3.1A)
CUO  B9007 (-3.3A)
CUO  B9007 (-3.3A)
 0.99A 5mi1A-4bedB:
undetectable		 5mi1A-4bedB:
15.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MI2_A_CUA601_0
(LACCASE 2)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		4 / 4 HIS A  60
HIS A 210
HIS A  69
HIS A  42
 CUO  A9001 (-3.1A)
CUO  A9001 (-3.3A)
CUO  A9001 (-3.1A)
CUO  A9001 (-3.4A)
 0.93A 5mi2A-4bedA:
undetectable		 5mi2A-4bedA:
16.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MI2_A_CUA601_0
(LACCASE 2)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		4 / 4 HIS A 482
HIS A 633
HIS A 491
HIS A 462
 CUO  A9002 (-3.4A)
CUO  A9002 (-3.3A)
CUO  A9002 (-3.4A)
CUO  A9002 (-3.2A)
 0.97A 5mi2A-4bedA:
undetectable		 5mi2A-4bedA:
16.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MI2_A_CUA601_0
(LACCASE 2)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		4 / 4 HIS A 896
HIS A1046
HIS A 905
HIS A 876
 CUO  A9003 (-3.4A)
CUO  A9003 (-3.2A)
CUO  A9003 (-3.5A)
CUO  A9003 (-3.3A)
 0.94A 5mi2A-4bedA:
undetectable		 5mi2A-4bedA:
16.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MI2_A_CUA601_0
(LACCASE 2)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		4 / 4 HIS A1019
HIS A 905
HIS A 876
HIS A1046
 CUO  A9003 (-3.4A)
CUO  A9003 (-3.5A)
CUO  A9003 (-3.3A)
CUO  A9003 (-3.2A)
 0.98A 5mi2A-4bedA:
undetectable		 5mi2A-4bedA:
16.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MI2_A_CUA601_0
(LACCASE 2)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		4 / 4 HIS A1311
HIS A1455
HIS A1320
HIS A1293
 CUO  A9004 (-3.4A)
CUO  A9004 (-3.3A)
CUO  A9004 (-3.5A)
CUO  A9004 (-3.2A)
 0.93A 5mi2A-4bedA:
undetectable		 5mi2A-4bedA:
16.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MI2_A_CUA601_0
(LACCASE 2)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		4 / 4 HIS A1428
HIS A1320
HIS A1293
HIS A1455
 CUO  A9004 (-3.4A)
CUO  A9004 (-3.5A)
CUO  A9004 (-3.2A)
CUO  A9004 (-3.3A)
 0.96A 5mi2A-4bedA:
undetectable		 5mi2A-4bedA:
16.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MI2_A_CUA601_0
(LACCASE 2)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		4 / 4 HIS B1725
HIS B1878
HIS B1734
HIS B1705
 CUO  B9005 (-3.1A)
CUO  B9005 (-3.3A)
CUO  B9005 (-3.4A)
CUO  B9005 (-3.2A)
 1.01A 5mi2A-4bedB:
undetectable		 5mi2A-4bedB:
15.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MI2_A_CUA601_0
(LACCASE 2)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		4 / 4 HIS B2561
HIS B2701
HIS B2570
HIS B2542
 CUO  B9007 (-3.3A)
CUO  B9007 (-3.1A)
CUO  B9007 (-3.3A)
CUO  B9007 (-3.3A)
 0.99A 5mi2A-4bedB:
undetectable		 5mi2A-4bedB:
15.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIA_A_CUA601_0
(LACCASE 2)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		4 / 4 HIS A  60
HIS A 210
HIS A  69
HIS A  42
 CUO  A9001 (-3.1A)
CUO  A9001 (-3.3A)
CUO  A9001 (-3.1A)
CUO  A9001 (-3.4A)
 0.93A 5miaA-4bedA:
undetectable		 5miaA-4bedA:
16.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIA_A_CUA601_0
(LACCASE 2)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		4 / 4 HIS A 482
HIS A 633
HIS A 491
HIS A 462
 CUO  A9002 (-3.4A)
CUO  A9002 (-3.3A)
CUO  A9002 (-3.4A)
CUO  A9002 (-3.2A)
 0.97A 5miaA-4bedA:
undetectable		 5miaA-4bedA:
16.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIA_A_CUA601_0
(LACCASE 2)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		4 / 4 HIS A 606
HIS A 491
HIS A 462
HIS A 633
 CUO  A9002 (-3.3A)
CUO  A9002 (-3.4A)
CUO  A9002 (-3.2A)
CUO  A9002 (-3.3A)
 1.02A 5miaA-4bedA:
undetectable		 5miaA-4bedA:
16.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIA_A_CUA601_0
(LACCASE 2)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		4 / 4 HIS A 896
HIS A1046
HIS A 905
HIS A 876
 CUO  A9003 (-3.4A)
CUO  A9003 (-3.2A)
CUO  A9003 (-3.5A)
CUO  A9003 (-3.3A)
 0.94A 5miaA-4bedA:
undetectable		 5miaA-4bedA:
16.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIA_A_CUA601_0
(LACCASE 2)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		4 / 4 HIS A1019
HIS A 905
HIS A 876
HIS A1046
 CUO  A9003 (-3.4A)
CUO  A9003 (-3.5A)
CUO  A9003 (-3.3A)
CUO  A9003 (-3.2A)
 0.98A 5miaA-4bedA:
undetectable		 5miaA-4bedA:
16.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIA_A_CUA601_0
(LACCASE 2)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		4 / 4 HIS A1311
HIS A1455
HIS A1320
HIS A1293
 CUO  A9004 (-3.4A)
CUO  A9004 (-3.3A)
CUO  A9004 (-3.5A)
CUO  A9004 (-3.2A)
 0.93A 5miaA-4bedA:
undetectable		 5miaA-4bedA:
16.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIA_A_CUA601_0
(LACCASE 2)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		4 / 4 HIS A1428
HIS A1320
HIS A1293
HIS A1455
 CUO  A9004 (-3.4A)
CUO  A9004 (-3.5A)
CUO  A9004 (-3.2A)
CUO  A9004 (-3.3A)
 0.96A 5miaA-4bedA:
undetectable		 5miaA-4bedA:
16.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIA_A_CUA601_0
(LACCASE 2)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		4 / 4 HIS B1725
HIS B1878
HIS B1734
HIS B1705
 CUO  B9005 (-3.1A)
CUO  B9005 (-3.3A)
CUO  B9005 (-3.4A)
CUO  B9005 (-3.2A)
 1.02A 5miaA-4bedB:
3.6		 5miaA-4bedB:
15.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIA_A_CUA601_0
(LACCASE 2)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		4 / 4 HIS B2561
HIS B2701
HIS B2570
HIS B2542
 CUO  B9007 (-3.3A)
CUO  B9007 (-3.1A)
CUO  B9007 (-3.3A)
CUO  B9007 (-3.3A)
 0.99A 5miaA-4bedB:
3.6		 5miaA-4bedB:
15.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIB_A_CUA601_0
(LACCASE 2)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		4 / 4 HIS A  60
HIS A 210
HIS A  69
HIS A  42
 CUO  A9001 (-3.1A)
CUO  A9001 (-3.3A)
CUO  A9001 (-3.1A)
CUO  A9001 (-3.4A)
 0.93A 5mibA-4bedA:
undetectable		 5mibA-4bedA:
16.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIB_A_CUA601_0
(LACCASE 2)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		4 / 4 HIS A 482
HIS A 633
HIS A 491
HIS A 462
 CUO  A9002 (-3.4A)
CUO  A9002 (-3.3A)
CUO  A9002 (-3.4A)
CUO  A9002 (-3.2A)
 0.97A 5mibA-4bedA:
undetectable		 5mibA-4bedA:
16.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIB_A_CUA601_0
(LACCASE 2)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		4 / 4 HIS A 896
HIS A1046
HIS A 905
HIS A 876
 CUO  A9003 (-3.4A)
CUO  A9003 (-3.2A)
CUO  A9003 (-3.5A)
CUO  A9003 (-3.3A)
 0.94A 5mibA-4bedA:
undetectable		 5mibA-4bedA:
16.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIB_A_CUA601_0
(LACCASE 2)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		4 / 4 HIS A1019
HIS A 905
HIS A 876
HIS A1046
 CUO  A9003 (-3.4A)
CUO  A9003 (-3.5A)
CUO  A9003 (-3.3A)
CUO  A9003 (-3.2A)
 0.98A 5mibA-4bedA:
undetectable		 5mibA-4bedA:
16.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIB_A_CUA601_0
(LACCASE 2)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		4 / 4 HIS A1311
HIS A1455
HIS A1320
HIS A1293
 CUO  A9004 (-3.4A)
CUO  A9004 (-3.3A)
CUO  A9004 (-3.5A)
CUO  A9004 (-3.2A)
 0.93A 5mibA-4bedA:
undetectable		 5mibA-4bedA:
16.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIB_A_CUA601_0
(LACCASE 2)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		4 / 4 HIS A1428
HIS A1320
HIS A1293
HIS A1455
 CUO  A9004 (-3.4A)
CUO  A9004 (-3.5A)
CUO  A9004 (-3.2A)
CUO  A9004 (-3.3A)
 0.96A 5mibA-4bedA:
undetectable		 5mibA-4bedA:
16.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIB_A_CUA601_0
(LACCASE 2)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		4 / 4 HIS B1725
HIS B1878
HIS B1734
HIS B1705
 CUO  B9005 (-3.1A)
CUO  B9005 (-3.3A)
CUO  B9005 (-3.4A)
CUO  B9005 (-3.2A)
 1.01A 5mibA-4bedB:
3.6		 5mibA-4bedB:
15.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIB_A_CUA601_0
(LACCASE 2)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		4 / 4 HIS B2561
HIS B2701
HIS B2570
HIS B2542
 CUO  B9007 (-3.3A)
CUO  B9007 (-3.1A)
CUO  B9007 (-3.3A)
CUO  B9007 (-3.3A)
 0.99A 5mibA-4bedB:
3.6		 5mibA-4bedB:
15.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIC_A_CUA601_0
(LACCASE 2)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		4 / 4 HIS A  60
HIS A 210
HIS A  69
HIS A  42
 CUO  A9001 (-3.1A)
CUO  A9001 (-3.3A)
CUO  A9001 (-3.1A)
CUO  A9001 (-3.4A)
 0.93A 5micA-4bedA:
undetectable		 5micA-4bedA:
16.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIC_A_CUA601_0
(LACCASE 2)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		4 / 4 HIS A 482
HIS A 633
HIS A 491
HIS A 462
 CUO  A9002 (-3.4A)
CUO  A9002 (-3.3A)
CUO  A9002 (-3.4A)
CUO  A9002 (-3.2A)
 0.97A 5micA-4bedA:
undetectable		 5micA-4bedA:
16.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIC_A_CUA601_0
(LACCASE 2)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		4 / 4 HIS A 896
HIS A1046
HIS A 905
HIS A 876
 CUO  A9003 (-3.4A)
CUO  A9003 (-3.2A)
CUO  A9003 (-3.5A)
CUO  A9003 (-3.3A)
 0.94A 5micA-4bedA:
undetectable		 5micA-4bedA:
16.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIC_A_CUA601_0
(LACCASE 2)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		4 / 4 HIS A1019
HIS A 905
HIS A 876
HIS A1046
 CUO  A9003 (-3.4A)
CUO  A9003 (-3.5A)
CUO  A9003 (-3.3A)
CUO  A9003 (-3.2A)
 0.98A 5micA-4bedA:
undetectable		 5micA-4bedA:
16.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIC_A_CUA601_0
(LACCASE 2)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		4 / 4 HIS A1311
HIS A1455
HIS A1320
HIS A1293
 CUO  A9004 (-3.4A)
CUO  A9004 (-3.3A)
CUO  A9004 (-3.5A)
CUO  A9004 (-3.2A)
 0.92A 5micA-4bedA:
undetectable		 5micA-4bedA:
16.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIC_A_CUA601_0
(LACCASE 2)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		4 / 4 HIS A1428
HIS A1320
HIS A1293
HIS A1455
 CUO  A9004 (-3.4A)
CUO  A9004 (-3.5A)
CUO  A9004 (-3.2A)
CUO  A9004 (-3.3A)
 0.96A 5micA-4bedA:
undetectable		 5micA-4bedA:
16.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIC_A_CUA601_0
(LACCASE 2)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		4 / 4 HIS B1725
HIS B1878
HIS B1734
HIS B1705
 CUO  B9005 (-3.1A)
CUO  B9005 (-3.3A)
CUO  B9005 (-3.4A)
CUO  B9005 (-3.2A)
 1.01A 5micA-4bedB:
undetectable		 5micA-4bedB:
15.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIC_A_CUA601_0
(LACCASE 2)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		4 / 4 HIS B2561
HIS B2701
HIS B2570
HIS B2542
 CUO  B9007 (-3.3A)
CUO  B9007 (-3.1A)
CUO  B9007 (-3.3A)
CUO  B9007 (-3.3A)
 0.99A 5micA-4bedB:
undetectable		 5micA-4bedB:
15.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MID_A_CUA601_0
(LACCASE 2)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		4 / 4 HIS A  60
HIS A 210
HIS A  69
HIS A  42
 CUO  A9001 (-3.1A)
CUO  A9001 (-3.3A)
CUO  A9001 (-3.1A)
CUO  A9001 (-3.4A)
 0.93A 5midA-4bedA:
undetectable		 5midA-4bedA:
16.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MID_A_CUA601_0
(LACCASE 2)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		4 / 4 HIS A 482
HIS A 633
HIS A 491
HIS A 462
 CUO  A9002 (-3.4A)
CUO  A9002 (-3.3A)
CUO  A9002 (-3.4A)
CUO  A9002 (-3.2A)
 0.97A 5midA-4bedA:
undetectable		 5midA-4bedA:
16.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MID_A_CUA601_0
(LACCASE 2)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		4 / 4 HIS A 606
HIS A 491
HIS A 462
HIS A 633
 CUO  A9002 (-3.3A)
CUO  A9002 (-3.4A)
CUO  A9002 (-3.2A)
CUO  A9002 (-3.3A)
 1.02A 5midA-4bedA:
undetectable		 5midA-4bedA:
16.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MID_A_CUA601_0
(LACCASE 2)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		4 / 4 HIS A 896
HIS A1046
HIS A 905
HIS A 876
 CUO  A9003 (-3.4A)
CUO  A9003 (-3.2A)
CUO  A9003 (-3.5A)
CUO  A9003 (-3.3A)
 0.94A 5midA-4bedA:
undetectable		 5midA-4bedA:
16.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MID_A_CUA601_0
(LACCASE 2)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		4 / 4 HIS A1019
HIS A 905
HIS A 876
HIS A1046
 CUO  A9003 (-3.4A)
CUO  A9003 (-3.5A)
CUO  A9003 (-3.3A)
CUO  A9003 (-3.2A)
 0.98A 5midA-4bedA:
undetectable		 5midA-4bedA:
16.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MID_A_CUA601_0
(LACCASE 2)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		4 / 4 HIS A1311
HIS A1455
HIS A1320
HIS A1293
 CUO  A9004 (-3.4A)
CUO  A9004 (-3.3A)
CUO  A9004 (-3.5A)
CUO  A9004 (-3.2A)
 0.93A 5midA-4bedA:
undetectable		 5midA-4bedA:
16.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MID_A_CUA601_0
(LACCASE 2)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		4 / 4 HIS A1428
HIS A1320
HIS A1293
HIS A1455
 CUO  A9004 (-3.4A)
CUO  A9004 (-3.5A)
CUO  A9004 (-3.2A)
CUO  A9004 (-3.3A)
 0.95A 5midA-4bedA:
undetectable		 5midA-4bedA:
16.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MID_A_CUA601_0
(LACCASE 2)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		4 / 4 HIS B1725
HIS B1878
HIS B1734
HIS B1705
 CUO  B9005 (-3.1A)
CUO  B9005 (-3.3A)
CUO  B9005 (-3.4A)
CUO  B9005 (-3.2A)
 1.02A 5midA-4bedB:
3.6		 5midA-4bedB:
15.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MID_A_CUA601_0
(LACCASE 2)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		4 / 4 HIS B2561
HIS B2701
HIS B2570
HIS B2542
 CUO  B9007 (-3.3A)
CUO  B9007 (-3.1A)
CUO  B9007 (-3.3A)
CUO  B9007 (-3.3A)
 0.99A 5midA-4bedB:
3.6		 5midA-4bedB:
15.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIE_A_CUA601_0
(LACCASE 2)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		4 / 4 HIS A  60
HIS A 210
HIS A  69
HIS A  42
 CUO  A9001 (-3.1A)
CUO  A9001 (-3.3A)
CUO  A9001 (-3.1A)
CUO  A9001 (-3.4A)
 0.93A 5mieA-4bedA:
undetectable		 5mieA-4bedA:
16.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIE_A_CUA601_0
(LACCASE 2)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		4 / 4 HIS A 482
HIS A 633
HIS A 491
HIS A 462
 CUO  A9002 (-3.4A)
CUO  A9002 (-3.3A)
CUO  A9002 (-3.4A)
CUO  A9002 (-3.2A)
 0.97A 5mieA-4bedA:
undetectable		 5mieA-4bedA:
16.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIE_A_CUA601_0
(LACCASE 2)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		4 / 4 HIS A 606
HIS A 491
HIS A 462
HIS A 633
 CUO  A9002 (-3.3A)
CUO  A9002 (-3.4A)
CUO  A9002 (-3.2A)
CUO  A9002 (-3.3A)
 1.02A 5mieA-4bedA:
undetectable		 5mieA-4bedA:
16.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIE_A_CUA601_0
(LACCASE 2)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		4 / 4 HIS A 896
HIS A1046
HIS A 905
HIS A 876
 CUO  A9003 (-3.4A)
CUO  A9003 (-3.2A)
CUO  A9003 (-3.5A)
CUO  A9003 (-3.3A)
 0.95A 5mieA-4bedA:
undetectable		 5mieA-4bedA:
16.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIE_A_CUA601_0
(LACCASE 2)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		4 / 4 HIS A1019
HIS A 905
HIS A 876
HIS A1046
 CUO  A9003 (-3.4A)
CUO  A9003 (-3.5A)
CUO  A9003 (-3.3A)
CUO  A9003 (-3.2A)
 0.98A 5mieA-4bedA:
undetectable		 5mieA-4bedA:
16.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIE_A_CUA601_0
(LACCASE 2)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		4 / 4 HIS A1311
HIS A1455
HIS A1320
HIS A1293
 CUO  A9004 (-3.4A)
CUO  A9004 (-3.3A)
CUO  A9004 (-3.5A)
CUO  A9004 (-3.2A)
 0.93A 5mieA-4bedA:
undetectable		 5mieA-4bedA:
16.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIE_A_CUA601_0
(LACCASE 2)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		4 / 4 HIS A1428
HIS A1320
HIS A1293
HIS A1455
 CUO  A9004 (-3.4A)
CUO  A9004 (-3.5A)
CUO  A9004 (-3.2A)
CUO  A9004 (-3.3A)
 0.95A 5mieA-4bedA:
undetectable		 5mieA-4bedA:
16.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIE_A_CUA601_0
(LACCASE 2)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		4 / 4 HIS B1725
HIS B1878
HIS B1734
HIS B1705
 CUO  B9005 (-3.1A)
CUO  B9005 (-3.3A)
CUO  B9005 (-3.4A)
CUO  B9005 (-3.2A)
 1.02A 5mieA-4bedB:
3.7		 5mieA-4bedB:
15.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIE_A_CUA601_0
(LACCASE 2)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		4 / 4 HIS B2561
HIS B2701
HIS B2570
HIS B2542
 CUO  B9007 (-3.3A)
CUO  B9007 (-3.1A)
CUO  B9007 (-3.3A)
CUO  B9007 (-3.3A)
 0.99A 5mieA-4bedB:
3.7		 5mieA-4bedB:
15.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIG_A_CUA601_0
(LACCASE 2)		 1js8 HEMOCYANIN
(Enteroctopus
dofleini) 		3 / 3 HIS A2562
HIS A2571
HIS A2543
 CUO  A 888 (-3.4A)
CUO  A 888 (-3.3A)
CUO  A 888 (-3.4A)
 0.31A 5migA-1js8A:
undetectable		 5migA-1js8A:
21.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIG_A_CUA601_0
(LACCASE 2)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		3 / 3 HIS A  60
HIS A  69
HIS A  42
 CUO  A9001 (-3.1A)
CUO  A9001 (-3.1A)
CUO  A9001 (-3.4A)
 0.33A 5migA-4bedA:
undetectable		 5migA-4bedA:
16.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIG_A_CUA601_0
(LACCASE 2)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		3 / 3 HIS A 482
HIS A 491
HIS A 462
 CUO  A9002 (-3.4A)
CUO  A9002 (-3.4A)
CUO  A9002 (-3.2A)
 0.36A 5migA-4bedA:
undetectable		 5migA-4bedA:
16.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIG_A_CUA601_0
(LACCASE 2)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		3 / 3 HIS A 896
HIS A 905
HIS A 876
 CUO  A9003 (-3.4A)
CUO  A9003 (-3.5A)
CUO  A9003 (-3.3A)
 0.39A 5migA-4bedA:
undetectable		 5migA-4bedA:
16.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIG_A_CUA601_0
(LACCASE 2)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		3 / 3 HIS A1311
HIS A1320
HIS A1293
 CUO  A9004 (-3.4A)
CUO  A9004 (-3.5A)
CUO  A9004 (-3.2A)
 0.31A 5migA-4bedA:
undetectable		 5migA-4bedA:
16.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIG_A_CUA601_0
(LACCASE 2)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		3 / 3 HIS B1725
HIS B1734
HIS B1705
 CUO  B9005 (-3.1A)
CUO  B9005 (-3.4A)
CUO  B9005 (-3.2A)
 0.36A 5migA-4bedB:
3.6		 5migA-4bedB:
15.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIG_A_CUA601_0
(LACCASE 2)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		3 / 3 HIS B2141
HIS B2150
HIS B2122
 CUO  B9006 (-3.1A)
CUO  B9006 (-3.3A)
CUO  B9006 (-3.2A)
 0.42A 5migA-4bedB:
3.6		 5migA-4bedB:
15.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIG_A_CUA601_0
(LACCASE 2)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		3 / 3 HIS B2561
HIS B2570
HIS B2542
 CUO  B9007 (-3.3A)
CUO  B9007 (-3.3A)
CUO  B9007 (-3.3A)
 0.36A 5migA-4bedB:
3.6		 5migA-4bedB:
15.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OEX_A_CUA604_0
(THIOCYANATE
DEHYDROGENASE)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		3 / 3 HIS A 632
HIS A 633
HIS A 491
 None
CUO  A9002 (-3.3A)
CUO  A9002 (-3.4A)
 0.97A 5oexA-4bedA:
undetectable		 5oexA-4bedA:
13.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5U6M_B_SALB503_1
(UDP-GLYCOSYLTRANSFER
ASE 74F2)		 1js8 HEMOCYANIN
(Enteroctopus
dofleini) 		4 / 7 THR A2705
HIS A2702
PHE A2698
MET A2686
 None
CUO  A 888 (-3.3A)
None
None
 1.50A 5u6mB-1js8A:
undetectable		 5u6mB-1js8A:
21.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5U6M_B_SALB503_1
(UDP-GLYCOSYLTRANSFER
ASE 74F2)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		4 / 7 THR A1049
HIS A1046
PHE A1042
MET A1030
 None
CUO  A9003 (-3.2A)
CUO  A9003 ( 4.9A)
None
 1.39A 5u6mB-4bedA:
undetectable		 5u6mB-4bedA:
13.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5W97_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1js8 HEMOCYANIN
(Enteroctopus
dofleini) 		3 / 3 HIS A2671
HIS A2702
HIS A2701
 CUO  A 888 (-3.4A)
CUO  A 888 (-3.3A)
None
 0.71A 5w97a-1js8A:
0.7		 5w97a-1js8A:
21.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5W97_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		3 / 3 HIS B2946
HIS B3106
HIS B2974
 CUO  B9008 (-3.1A)
CUO  B9008 (-3.3A)
CUO  B9008 (-2.9A)
 0.69A 5w97a-4bedB:
undetectable		 5w97a-4bedB:
14.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WAU_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1js8 HEMOCYANIN
(Enteroctopus
dofleini) 		3 / 3 HIS A2671
HIS A2702
HIS A2701
 CUO  A 888 (-3.4A)
CUO  A 888 (-3.3A)
None
 0.73A 5waua-1js8A:
undetectable		 5waua-1js8A:
21.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WAU_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		3 / 3 HIS B2946
HIS B3106
HIS B2974
 CUO  B9008 (-3.1A)
CUO  B9008 (-3.3A)
CUO  B9008 (-2.9A)
 0.74A 5waua-4bedB:
undetectable		 5waua-4bedB:
14.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X19_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		3 / 3 HIS B2946
HIS B3106
HIS B2974
 CUO  B9008 (-3.1A)
CUO  B9008 (-3.3A)
CUO  B9008 (-2.9A)
 0.68A 5x19A-4bedB:
undetectable		 5x19A-4bedB:
14.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X19_N_CUN603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1js8 HEMOCYANIN
(Enteroctopus
dofleini) 		3 / 3 HIS A2671
HIS A2702
HIS A2701
 CUO  A 888 (-3.4A)
CUO  A 888 (-3.3A)
None
 0.71A 5x19N-1js8A:
0.8		 5x19N-1js8A:
21.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X19_N_CUN603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		3 / 3 HIS B2946
HIS B3106
HIS B2974
 CUO  B9008 (-3.1A)
CUO  B9008 (-3.3A)
CUO  B9008 (-2.9A)
 0.72A 5x19N-4bedB:
1.0		 5x19N-4bedB:
14.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1B_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1js8 HEMOCYANIN
(Enteroctopus
dofleini) 		3 / 3 HIS A2671
HIS A2702
HIS A2701
 CUO  A 888 (-3.4A)
CUO  A 888 (-3.3A)
None
 0.72A 5x1bA-1js8A:
undetectable		 5x1bA-1js8A:
21.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1B_C_CHDC305_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1js8 HEMOCYANIN
(Enteroctopus
dofleini) 		4 / 7 HIS A2562
ASP A2695
THR A2692
TYR A2691
 CUO  A 888 (-3.4A)
None
CUO  A 888 ( 4.9A)
None
 1.17A 5x1bA-1js8A:
undetectable
5x1bC-1js8A:
1.2
5x1bP-1js8A:
0.9		 5x1bA-1js8A:
21.26
5x1bC-1js8A:
22.49
5x1bP-1js8A:
22.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1B_C_CHDC305_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		4 / 7 HIS A 482
ASP A 626
THR A 623
TYR A 622
 CUO  A9002 (-3.4A)
None
CUO  A9002 ( 4.5A)
None
 1.11A 5x1bA-4bedA:
undetectable
5x1bC-4bedA:
undetectable
5x1bP-4bedA:
undetectable		 5x1bA-4bedA:
14.65
5x1bC-4bedA:
9.60
5x1bP-4bedA:
9.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1B_N_CUN603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1js8 HEMOCYANIN
(Enteroctopus
dofleini) 		3 / 3 HIS A2671
HIS A2702
HIS A2701
 CUO  A 888 (-3.4A)
CUO  A 888 (-3.3A)
None
 0.65A 5x1bN-1js8A:
undetectable		 5x1bN-1js8A:
21.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1F_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		3 / 3 HIS B2946
HIS B3106
HIS B2974
 CUO  B9008 (-3.1A)
CUO  B9008 (-3.3A)
CUO  B9008 (-2.9A)
 0.67A 5x1fA-4bedB:
undetectable		 5x1fA-4bedB:
14.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1F_N_CUN603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1js8 HEMOCYANIN
(Enteroctopus
dofleini) 		3 / 3 HIS A2671
HIS A2702
HIS A2701
 CUO  A 888 (-3.4A)
CUO  A 888 (-3.3A)
None
 0.67A 5x1fN-1js8A:
0.6		 5x1fN-1js8A:
21.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1F_N_CUN603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		3 / 3 HIS B2946
HIS B3106
HIS B2974
 CUO  B9008 (-3.1A)
CUO  B9008 (-3.3A)
CUO  B9008 (-2.9A)
 0.68A 5x1fN-4bedB:
0.3		 5x1fN-4bedB:
14.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDQ_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		3 / 3 HIS B2946
HIS B3106
HIS B2974
 CUO  B9008 (-3.1A)
CUO  B9008 (-3.3A)
CUO  B9008 (-2.9A)
 0.76A 5xdqA-4bedB:
undetectable		 5xdqA-4bedB:
14.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDX_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1js8 HEMOCYANIN
(Enteroctopus
dofleini) 		3 / 3 HIS A2671
HIS A2702
HIS A2701
 CUO  A 888 (-3.4A)
CUO  A 888 (-3.3A)
None
 0.72A 5xdxA-1js8A:
0.0		 5xdxA-1js8A:
21.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDX_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		3 / 3 HIS B2946
HIS B3106
HIS B2974
 CUO  B9008 (-3.1A)
CUO  B9008 (-3.3A)
CUO  B9008 (-2.9A)
 0.72A 5xdxA-4bedB:
undetectable		 5xdxA-4bedB:
14.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDX_N_CUN603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1js8 HEMOCYANIN
(Enteroctopus
dofleini) 		3 / 3 HIS A2671
HIS A2702
HIS A2701
 CUO  A 888 (-3.4A)
CUO  A 888 (-3.3A)
None
 0.72A 5xdxN-1js8A:
undetectable		 5xdxN-1js8A:
21.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDX_N_CUN603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		3 / 3 HIS B2946
HIS B3106
HIS B2974
 CUO  B9008 (-3.1A)
CUO  B9008 (-3.3A)
CUO  B9008 (-2.9A)
 0.71A 5xdxN-4bedB:
undetectable		 5xdxN-4bedB:
14.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y2T_A_8LXA501_0
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3wky PROPHENOLOXIDASE B
(Marsupenaeus
japonicus) 		5 / 12 PHE A  72
GLY A 365
LEU A 297
ILE A 283
HIS A 357
 CUO  A 708 (-4.6A)
None
None
None
CUO  A 708 (-3.3A)
 1.27A 5y2tA-3wkyA:
undetectable		 5y2tA-3wkyA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z0F_B_DAHB98_0
(MELC
TYROSINASE)		 1js8 HEMOCYANIN
(Enteroctopus
dofleini) 		5 / 11 HIS A2543
HIS A2562
HIS A2671
ASN A2672
HIS A2675
 CUO  A 888 (-3.4A)
CUO  A 888 (-3.4A)
CUO  A 888 (-3.4A)
None
CUO  A 888 (-3.3A)
 0.60A 5z0fA-1js8A:
23.5
5z0fB-1js8A:
0.0		 5z0fA-1js8A:
9.57
5z0fB-1js8A:
11.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z0F_B_DAHB98_0
(MELC
TYROSINASE)		 1js8 HEMOCYANIN
(Enteroctopus
dofleini) 		5 / 11 HIS A2543
HIS A2571
HIS A2671
ASN A2672
HIS A2675
 CUO  A 888 (-3.4A)
CUO  A 888 (-3.3A)
CUO  A 888 (-3.4A)
None
CUO  A 888 (-3.3A)
 1.48A 5z0fA-1js8A:
23.5
5z0fB-1js8A:
0.0		 5z0fA-1js8A:
9.57
5z0fB-1js8A:
11.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z0F_B_DAHB98_0
(MELC
TYROSINASE)		 3wky PROPHENOLOXIDASE B
(Marsupenaeus
japonicus) 		5 / 11 HIS A 199
HIS A 203
HIS A 357
ASN A 358
HIS A 361
 CUO  A 708 (-3.3A)
CUO  A 708 (-3.5A)
CUO  A 708 (-3.3A)
None
CUO  A 708 (-3.2A)
 0.79A 5z0fA-3wkyA:
10.2
5z0fB-3wkyA:
undetectable		 5z0fA-3wkyA:
8.13
5z0fB-3wkyA:
8.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z0F_B_DAHB98_0
(MELC
TYROSINASE)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		5 / 11 HIS A 462
HIS A 491
HIS A 602
ASN A 603
HIS A 606
 CUO  A9002 (-3.2A)
CUO  A9002 (-3.4A)
CUO  A9002 (-3.4A)
None
CUO  A9002 (-3.3A)
 1.46A 5z0fA-4bedA:
20.9
5z0fB-4bedA:
undetectable		 5z0fA-4bedA:
5.49
5z0fB-4bedA:
4.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z0F_B_DAHB98_0
(MELC
TYROSINASE)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		5 / 11 HIS A 876
HIS A 896
HIS A1015
ASN A1016
HIS A1019
 CUO  A9003 (-3.3A)
CUO  A9003 (-3.4A)
CUO  A9003 (-3.1A)
None
CUO  A9003 (-3.4A)
 1.09A 5z0fA-4bedA:
20.9
5z0fB-4bedA:
undetectable		 5z0fA-4bedA:
5.49
5z0fB-4bedA:
4.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z0F_B_DAHB98_0
(MELC
TYROSINASE)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		5 / 11 HIS B1705
HIS B1725
HIS B1847
ASN B1848
HIS B1851
 CUO  B9005 (-3.2A)
CUO  B9005 (-3.1A)
CUO  B9005 (-3.2A)
None
CUO  B9005 (-3.2A)
 0.89A 5z0fA-4bedB:
21.5
5z0fB-4bedB:
undetectable		 5z0fA-4bedB:
4.44
5z0fB-4bedB:
4.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z0F_B_DAHB98_0
(MELC
TYROSINASE)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		5 / 11 HIS B2122
HIS B2141
HIS B2260
ASN B2261
HIS B2264
 CUO  B9006 (-3.2A)
CUO  B9006 (-3.1A)
CUO  B9006 (-3.2A)
None
CUO  B9006 (-3.2A)
 0.98A 5z0fA-4bedB:
21.5
5z0fB-4bedB:
undetectable		 5z0fA-4bedB:
4.44
5z0fB-4bedB:
4.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z0F_B_DAHB98_0
(MELC
TYROSINASE)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		5 / 11 HIS B2946
HIS B2974
ASN B3076
HIS B3079
SER B3096
 CUO  B9008 (-3.1A)
CUO  B9008 (-2.9A)
None
CUO  B9008 (-3.5A)
CUO  B9008 ( 4.7A)
 1.49A 5z0fA-4bedB:
21.5
5z0fB-4bedB:
undetectable		 5z0fA-4bedB:
4.44
5z0fB-4bedB:
4.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z0F_B_DAHB98_0
(MELC
TYROSINASE)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		5 / 11 HIS B2946
HIS B3075
ASN B3076
HIS B3079
SER B3096
 CUO  B9008 (-3.1A)
CUO  B9008 (-2.8A)
None
CUO  B9008 (-3.5A)
CUO  B9008 ( 4.7A)
 0.49A 5z0fA-4bedB:
21.5
5z0fB-4bedB:
undetectable		 5z0fA-4bedB:
4.44
5z0fB-4bedB:
4.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z0G_B_DAHB98_0
(MELC
TYROSINASE)		 1js8 HEMOCYANIN
(Enteroctopus
dofleini) 		5 / 11 HIS A2543
HIS A2562
HIS A2671
ASN A2672
HIS A2675
 CUO  A 888 (-3.4A)
CUO  A 888 (-3.4A)
CUO  A 888 (-3.4A)
None
CUO  A 888 (-3.3A)
 0.57A 5z0gA-1js8A:
23.0
5z0gB-1js8A:
0.0		 5z0gA-1js8A:
9.57
5z0gB-1js8A:
11.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z0G_B_DAHB98_0
(MELC
TYROSINASE)		 3wky PROPHENOLOXIDASE B
(Marsupenaeus
japonicus) 		5 / 11 HIS A 199
HIS A 203
HIS A 357
ASN A 358
HIS A 361
 CUO  A 708 (-3.3A)
CUO  A 708 (-3.5A)
CUO  A 708 (-3.3A)
None
CUO  A 708 (-3.2A)
 0.77A 5z0gA-3wkyA:
10.2
5z0gB-3wkyA:
undetectable		 5z0gA-3wkyA:
8.13
5z0gB-3wkyA:
8.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z0G_B_DAHB98_0
(MELC
TYROSINASE)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		5 / 11 HIS A  42
HIS A  69
HIS A 179
ASN A 180
HIS A 183
 CUO  A9001 (-3.4A)
CUO  A9001 (-3.1A)
CUO  A9001 (-3.4A)
None
CUO  A9001 (-3.4A)
 1.48A 5z0gA-4bedA:
20.4
5z0gB-4bedA:
undetectable		 5z0gA-4bedA:
5.49
5z0gB-4bedA:
4.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z0G_B_DAHB98_0
(MELC
TYROSINASE)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		5 / 11 HIS A 462
HIS A 491
HIS A 602
ASN A 603
HIS A 606
 CUO  A9002 (-3.2A)
CUO  A9002 (-3.4A)
CUO  A9002 (-3.4A)
None
CUO  A9002 (-3.3A)
 1.47A 5z0gA-4bedA:
20.4
5z0gB-4bedA:
undetectable		 5z0gA-4bedA:
5.49
5z0gB-4bedA:
4.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z0G_B_DAHB98_0
(MELC
TYROSINASE)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		5 / 11 HIS A 876
HIS A 896
HIS A1015
ASN A1016
HIS A1019
 CUO  A9003 (-3.3A)
CUO  A9003 (-3.4A)
CUO  A9003 (-3.1A)
None
CUO  A9003 (-3.4A)
 1.05A 5z0gA-4bedA:
20.4
5z0gB-4bedA:
undetectable		 5z0gA-4bedA:
5.49
5z0gB-4bedA:
4.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z0G_B_DAHB98_0
(MELC
TYROSINASE)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		5 / 11 HIS B1705
HIS B1725
HIS B1847
ASN B1848
HIS B1851
 CUO  B9005 (-3.2A)
CUO  B9005 (-3.1A)
CUO  B9005 (-3.2A)
None
CUO  B9005 (-3.2A)
 0.86A 5z0gA-4bedB:
21.2
5z0gB-4bedB:
undetectable		 5z0gA-4bedB:
4.44
5z0gB-4bedB:
4.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z0G_B_DAHB98_0
(MELC
TYROSINASE)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		5 / 11 HIS B2122
HIS B2141
HIS B2260
ASN B2261
HIS B2264
 CUO  B9006 (-3.2A)
CUO  B9006 (-3.1A)
CUO  B9006 (-3.2A)
None
CUO  B9006 (-3.2A)
 0.94A 5z0gA-4bedB:
21.2
5z0gB-4bedB:
undetectable		 5z0gA-4bedB:
4.44
5z0gB-4bedB:
4.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z0G_B_DAHB98_0
(MELC
TYROSINASE)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		5 / 11 HIS B2946
HIS B2965
HIS B3075
HIS B3079
SER B3096
 CUO  B9008 (-3.1A)
CUO  B9008 (-3.2A)
CUO  B9008 (-2.8A)
CUO  B9008 (-3.5A)
CUO  B9008 ( 4.7A)
 0.80A 5z0gA-4bedB:
21.2
5z0gB-4bedB:
undetectable		 5z0gA-4bedB:
4.44
5z0gB-4bedB:
4.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z0G_B_DAHB98_0
(MELC
TYROSINASE)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		5 / 11 HIS B2946
HIS B3075
ASN B3076
HIS B3079
SER B3096
 CUO  B9008 (-3.1A)
CUO  B9008 (-2.8A)
None
CUO  B9008 (-3.5A)
CUO  B9008 ( 4.7A)
 0.48A 5z0gA-4bedB:
21.2
5z0gB-4bedB:
undetectable		 5z0gA-4bedB:
4.44
5z0gB-4bedB:
4.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z0H_B_DAHB98_0
(MELC
TYROSINASE)		 1js8 HEMOCYANIN
(Enteroctopus
dofleini) 		5 / 11 HIS A2543
HIS A2562
HIS A2671
ASN A2672
HIS A2675
 CUO  A 888 (-3.4A)
CUO  A 888 (-3.4A)
CUO  A 888 (-3.4A)
None
CUO  A 888 (-3.3A)
 0.52A 5z0hA-1js8A:
23.0
5z0hB-1js8A:
0.0		 5z0hA-1js8A:
9.57
5z0hB-1js8A:
11.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z0H_B_DAHB98_0
(MELC
TYROSINASE)		 1js8 HEMOCYANIN
(Enteroctopus
dofleini) 		5 / 11 HIS A2543
HIS A2571
HIS A2671
ASN A2672
HIS A2675
 CUO  A 888 (-3.4A)
CUO  A 888 (-3.3A)
CUO  A 888 (-3.4A)
None
CUO  A 888 (-3.3A)
 1.42A 5z0hA-1js8A:
23.0
5z0hB-1js8A:
0.0		 5z0hA-1js8A:
9.57
5z0hB-1js8A:
11.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z0H_B_DAHB98_0
(MELC
TYROSINASE)		 3wky PROPHENOLOXIDASE B
(Marsupenaeus
japonicus) 		5 / 11 HIS A 199
HIS A 203
HIS A 357
ASN A 358
HIS A 361
 CUO  A 708 (-3.3A)
CUO  A 708 (-3.5A)
CUO  A 708 (-3.3A)
None
CUO  A 708 (-3.2A)
 0.75A 5z0hA-3wkyA:
10.5
5z0hB-3wkyA:
undetectable		 5z0hA-3wkyA:
8.13
5z0hB-3wkyA:
8.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z0H_B_DAHB98_0
(MELC
TYROSINASE)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		5 / 11 HIS A  42
HIS A  69
HIS A 179
ASN A 180
HIS A 183
 CUO  A9001 (-3.4A)
CUO  A9001 (-3.1A)
CUO  A9001 (-3.4A)
None
CUO  A9001 (-3.4A)
 1.40A 5z0hA-4bedA:
20.5
5z0hB-4bedA:
undetectable		 5z0hA-4bedA:
5.49
5z0hB-4bedA:
4.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z0H_B_DAHB98_0
(MELC
TYROSINASE)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		5 / 11 HIS A 462
HIS A 482
HIS A 602
ASN A 603
HIS A 606
 CUO  A9002 (-3.2A)
CUO  A9002 (-3.4A)
CUO  A9002 (-3.4A)
None
CUO  A9002 (-3.3A)
 1.03A 5z0hA-4bedA:
20.5
5z0hB-4bedA:
undetectable		 5z0hA-4bedA:
5.49
5z0hB-4bedA:
4.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z0H_B_DAHB98_0
(MELC
TYROSINASE)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		5 / 11 HIS A 462
HIS A 491
HIS A 602
ASN A 603
HIS A 606
 CUO  A9002 (-3.2A)
CUO  A9002 (-3.4A)
CUO  A9002 (-3.4A)
None
CUO  A9002 (-3.3A)
 1.40A 5z0hA-4bedA:
20.5
5z0hB-4bedA:
undetectable		 5z0hA-4bedA:
5.49
5z0hB-4bedA:
4.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z0H_B_DAHB98_0
(MELC
TYROSINASE)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		5 / 11 HIS B1705
HIS B1725
HIS B1847
ASN B1848
HIS B1851
 CUO  B9005 (-3.2A)
CUO  B9005 (-3.1A)
CUO  B9005 (-3.2A)
None
CUO  B9005 (-3.2A)
 0.85A 5z0hA-4bedB:
23.0
5z0hB-4bedB:
undetectable		 5z0hA-4bedB:
4.44
5z0hB-4bedB:
4.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z0H_B_DAHB98_0
(MELC
TYROSINASE)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		5 / 11 HIS B1705
HIS B1734
HIS B1847
ASN B1848
HIS B1851
 CUO  B9005 (-3.2A)
CUO  B9005 (-3.4A)
CUO  B9005 (-3.2A)
None
CUO  B9005 (-3.2A)
 1.47A 5z0hA-4bedB:
23.0
5z0hB-4bedB:
undetectable		 5z0hA-4bedB:
4.44
5z0hB-4bedB:
4.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z0H_B_DAHB98_0
(MELC
TYROSINASE)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		5 / 11 HIS B2542
HIS B2561
HIS B2670
ASN B2671
HIS B2674
 CUO  B9007 (-3.3A)
CUO  B9007 (-3.3A)
CUO  B9007 (-3.4A)
None
CUO  B9007 (-3.4A)
 0.92A 5z0hA-4bedB:
23.0
5z0hB-4bedB:
undetectable		 5z0hA-4bedB:
4.44
5z0hB-4bedB:
4.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z0H_B_DAHB98_0
(MELC
TYROSINASE)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		5 / 11 HIS B2542
HIS B2570
HIS B2670
ASN B2671
HIS B2674
 CUO  B9007 (-3.3A)
CUO  B9007 (-3.3A)
CUO  B9007 (-3.4A)
None
CUO  B9007 (-3.4A)
 1.48A 5z0hA-4bedB:
23.0
5z0hB-4bedB:
undetectable		 5z0hA-4bedB:
4.44
5z0hB-4bedB:
4.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z0H_B_DAHB98_0
(MELC
TYROSINASE)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		5 / 11 HIS B2946
HIS B2965
HIS B3075
HIS B3079
SER B3096
 CUO  B9008 (-3.1A)
CUO  B9008 (-3.2A)
CUO  B9008 (-2.8A)
CUO  B9008 (-3.5A)
CUO  B9008 ( 4.7A)
 0.75A 5z0hA-4bedB:
23.0
5z0hB-4bedB:
undetectable		 5z0hA-4bedB:
4.44
5z0hB-4bedB:
4.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z0H_B_DAHB98_0
(MELC
TYROSINASE)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		5 / 11 HIS B2946
HIS B2974
ASN B3076
HIS B3079
SER B3096
 CUO  B9008 (-3.1A)
CUO  B9008 (-2.9A)
None
CUO  B9008 (-3.5A)
CUO  B9008 ( 4.7A)
 1.41A 5z0hA-4bedB:
23.0
5z0hB-4bedB:
undetectable		 5z0hA-4bedB:
4.44
5z0hB-4bedB:
4.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z0H_B_DAHB98_0
(MELC
TYROSINASE)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		5 / 11 HIS B2946
HIS B3075
ASN B3076
HIS B3079
SER B3096
 CUO  B9008 (-3.1A)
CUO  B9008 (-2.8A)
None
CUO  B9008 (-3.5A)
CUO  B9008 ( 4.7A)
 0.45A 5z0hA-4bedB:
23.0
5z0hB-4bedB:
undetectable		 5z0hA-4bedB:
4.44
5z0hB-4bedB:
4.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z0I_B_DAHB98_0
(MELC
TYROSINASE)		 1js8 HEMOCYANIN
(Enteroctopus
dofleini) 		5 / 11 HIS A2543
HIS A2562
HIS A2671
ASN A2672
HIS A2675
 CUO  A 888 (-3.4A)
CUO  A 888 (-3.4A)
CUO  A 888 (-3.4A)
None
CUO  A 888 (-3.3A)
 0.54A 5z0iA-1js8A:
23.0
5z0iB-1js8A:
0.0		 5z0iA-1js8A:
9.57
5z0iB-1js8A:
11.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z0I_B_DAHB98_0
(MELC
TYROSINASE)		 1js8 HEMOCYANIN
(Enteroctopus
dofleini) 		5 / 11 HIS A2543
HIS A2571
HIS A2671
ASN A2672
HIS A2675
 CUO  A 888 (-3.4A)
CUO  A 888 (-3.3A)
CUO  A 888 (-3.4A)
None
CUO  A 888 (-3.3A)
 1.47A 5z0iA-1js8A:
23.0
5z0iB-1js8A:
0.0		 5z0iA-1js8A:
9.57
5z0iB-1js8A:
11.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z0I_B_DAHB98_0
(MELC
TYROSINASE)		 3wky PROPHENOLOXIDASE B
(Marsupenaeus
japonicus) 		5 / 11 HIS A 199
HIS A 203
HIS A 357
ASN A 358
HIS A 361
 CUO  A 708 (-3.3A)
CUO  A 708 (-3.5A)
CUO  A 708 (-3.3A)
None
CUO  A 708 (-3.2A)
 0.76A 5z0iA-3wkyA:
10.5
5z0iB-3wkyA:
undetectable		 5z0iA-3wkyA:
8.13
5z0iB-3wkyA:
8.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z0I_B_DAHB98_0
(MELC
TYROSINASE)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		5 / 11 HIS A 462
HIS A 482
HIS A 602
ASN A 603
HIS A 606
 CUO  A9002 (-3.2A)
CUO  A9002 (-3.4A)
CUO  A9002 (-3.4A)
None
CUO  A9002 (-3.3A)
 1.02A 5z0iA-4bedA:
20.5
5z0iB-4bedA:
undetectable		 5z0iA-4bedA:
5.49
5z0iB-4bedA:
4.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z0I_B_DAHB98_0
(MELC
TYROSINASE)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		5 / 11 HIS A 462
HIS A 491
HIS A 602
ASN A 603
HIS A 606
 CUO  A9002 (-3.2A)
CUO  A9002 (-3.4A)
CUO  A9002 (-3.4A)
None
CUO  A9002 (-3.3A)
 1.44A 5z0iA-4bedA:
20.5
5z0iB-4bedA:
undetectable		 5z0iA-4bedA:
5.49
5z0iB-4bedA:
4.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z0I_B_DAHB98_0
(MELC
TYROSINASE)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		5 / 11 HIS A 876
HIS A 896
HIS A1015
ASN A1016
HIS A1019
 CUO  A9003 (-3.3A)
CUO  A9003 (-3.4A)
CUO  A9003 (-3.1A)
None
CUO  A9003 (-3.4A)
 1.06A 5z0iA-4bedA:
20.5
5z0iB-4bedA:
undetectable		 5z0iA-4bedA:
5.49
5z0iB-4bedA:
4.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z0I_B_DAHB98_0
(MELC
TYROSINASE)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		5 / 11 HIS B1705
HIS B1725
HIS B1847
ASN B1848
HIS B1851
 CUO  B9005 (-3.2A)
CUO  B9005 (-3.1A)
CUO  B9005 (-3.2A)
None
CUO  B9005 (-3.2A)
 0.85A 5z0iA-4bedB:
23.0
5z0iB-4bedB:
undetectable		 5z0iA-4bedB:
4.44
5z0iB-4bedB:
4.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z0I_B_DAHB98_0
(MELC
TYROSINASE)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		5 / 11 HIS B2122
HIS B2141
HIS B2260
ASN B2261
HIS B2264
 CUO  B9006 (-3.2A)
CUO  B9006 (-3.1A)
CUO  B9006 (-3.2A)
None
CUO  B9006 (-3.2A)
 0.94A 5z0iA-4bedB:
23.0
5z0iB-4bedB:
undetectable		 5z0iA-4bedB:
4.44
5z0iB-4bedB:
4.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z0I_B_DAHB98_0
(MELC
TYROSINASE)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		5 / 11 HIS B2946
HIS B2965
HIS B3075
HIS B3079
SER B3096
 CUO  B9008 (-3.1A)
CUO  B9008 (-3.2A)
CUO  B9008 (-2.8A)
CUO  B9008 (-3.5A)
CUO  B9008 ( 4.7A)
 0.78A 5z0iA-4bedB:
23.0
5z0iB-4bedB:
undetectable		 5z0iA-4bedB:
4.44
5z0iB-4bedB:
4.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z0I_B_DAHB98_0
(MELC
TYROSINASE)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		5 / 11 HIS B2946
HIS B2974
ASN B3076
HIS B3079
SER B3096
 CUO  B9008 (-3.1A)
CUO  B9008 (-2.9A)
None
CUO  B9008 (-3.5A)
CUO  B9008 ( 4.7A)
 1.46A 5z0iA-4bedB:
23.0
5z0iB-4bedB:
undetectable		 5z0iA-4bedB:
4.44
5z0iB-4bedB:
4.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z0I_B_DAHB98_0
(MELC
TYROSINASE)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		5 / 11 HIS B2946
HIS B3075
ASN B3076
HIS B3079
SER B3096
 CUO  B9008 (-3.1A)
CUO  B9008 (-2.8A)
None
CUO  B9008 (-3.5A)
CUO  B9008 ( 4.7A)
 0.47A 5z0iA-4bedB:
23.0
5z0iB-4bedB:
undetectable		 5z0iA-4bedB:
4.44
5z0iB-4bedB:
4.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z0J_B_DAHB98_0
(MELC
TYROSINASE)		 1js8 HEMOCYANIN
(Enteroctopus
dofleini) 		5 / 11 HIS A2543
HIS A2562
HIS A2671
ASN A2672
HIS A2675
 CUO  A 888 (-3.4A)
CUO  A 888 (-3.4A)
CUO  A 888 (-3.4A)
None
CUO  A 888 (-3.3A)
 0.55A 5z0jA-1js8A:
23.1
5z0jB-1js8A:
0.0		 5z0jA-1js8A:
9.57
5z0jB-1js8A:
11.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z0J_B_DAHB98_0
(MELC
TYROSINASE)		 1js8 HEMOCYANIN
(Enteroctopus
dofleini) 		5 / 11 HIS A2543
HIS A2571
HIS A2671
ASN A2672
HIS A2675
 CUO  A 888 (-3.4A)
CUO  A 888 (-3.3A)
CUO  A 888 (-3.4A)
None
CUO  A 888 (-3.3A)
 1.49A 5z0jA-1js8A:
23.1
5z0jB-1js8A:
0.0		 5z0jA-1js8A:
9.57
5z0jB-1js8A:
11.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z0J_B_DAHB98_0
(MELC
TYROSINASE)		 3wky PROPHENOLOXIDASE B
(Marsupenaeus
japonicus) 		5 / 11 HIS A 199
HIS A 203
HIS A 357
ASN A 358
HIS A 361
 CUO  A 708 (-3.3A)
CUO  A 708 (-3.5A)
CUO  A 708 (-3.3A)
None
CUO  A 708 (-3.2A)
 0.74A 5z0jA-3wkyA:
10.1
5z0jB-3wkyA:
undetectable		 5z0jA-3wkyA:
8.13
5z0jB-3wkyA:
8.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z0J_B_DAHB98_0
(MELC
TYROSINASE)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		5 / 11 HIS A  42
HIS A  69
HIS A 179
ASN A 180
HIS A 183
 CUO  A9001 (-3.4A)
CUO  A9001 (-3.1A)
CUO  A9001 (-3.4A)
None
CUO  A9001 (-3.4A)
 1.46A 5z0jA-4bedA:
20.5
5z0jB-4bedA:
undetectable		 5z0jA-4bedA:
5.49
5z0jB-4bedA:
4.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z0J_B_DAHB98_0
(MELC
TYROSINASE)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		5 / 11 HIS A 462
HIS A 482
HIS A 602
ASN A 603
HIS A 606
 CUO  A9002 (-3.2A)
CUO  A9002 (-3.4A)
CUO  A9002 (-3.4A)
None
CUO  A9002 (-3.3A)
 1.02A 5z0jA-4bedA:
20.5
5z0jB-4bedA:
undetectable		 5z0jA-4bedA:
5.49
5z0jB-4bedA:
4.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z0J_B_DAHB98_0
(MELC
TYROSINASE)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		5 / 11 HIS A 462
HIS A 491
HIS A 602
ASN A 603
HIS A 606
 CUO  A9002 (-3.2A)
CUO  A9002 (-3.4A)
CUO  A9002 (-3.4A)
None
CUO  A9002 (-3.3A)
 1.46A 5z0jA-4bedA:
20.5
5z0jB-4bedA:
undetectable		 5z0jA-4bedA:
5.49
5z0jB-4bedA:
4.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z0J_B_DAHB98_0
(MELC
TYROSINASE)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		5 / 11 HIS A 876
HIS A 896
HIS A1015
ASN A1016
HIS A1019
 CUO  A9003 (-3.3A)
CUO  A9003 (-3.4A)
CUO  A9003 (-3.1A)
None
CUO  A9003 (-3.4A)
 1.06A 5z0jA-4bedA:
20.5
5z0jB-4bedA:
undetectable		 5z0jA-4bedA:
5.49
5z0jB-4bedA:
4.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z0J_B_DAHB98_0
(MELC
TYROSINASE)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		5 / 11 HIS B1705
HIS B1725
HIS B1847
ASN B1848
HIS B1851
 CUO  B9005 (-3.2A)
CUO  B9005 (-3.1A)
CUO  B9005 (-3.2A)
None
CUO  B9005 (-3.2A)
 0.86A 5z0jA-4bedB:
23.1
5z0jB-4bedB:
undetectable		 5z0jA-4bedB:
4.44
5z0jB-4bedB:
4.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z0J_B_DAHB98_0
(MELC
TYROSINASE)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		5 / 11 HIS B2122
HIS B2141
HIS B2260
ASN B2261
HIS B2264
 CUO  B9006 (-3.2A)
CUO  B9006 (-3.1A)
CUO  B9006 (-3.2A)
None
CUO  B9006 (-3.2A)
 0.94A 5z0jA-4bedB:
23.1
5z0jB-4bedB:
undetectable		 5z0jA-4bedB:
4.44
5z0jB-4bedB:
4.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z0J_B_DAHB98_0
(MELC
TYROSINASE)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		5 / 11 HIS B2946
HIS B2965
HIS B3075
HIS B3079
SER B3096
 CUO  B9008 (-3.1A)
CUO  B9008 (-3.2A)
CUO  B9008 (-2.8A)
CUO  B9008 (-3.5A)
CUO  B9008 ( 4.7A)
 0.76A 5z0jA-4bedB:
23.1
5z0jB-4bedB:
undetectable		 5z0jA-4bedB:
4.44
5z0jB-4bedB:
4.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z0J_B_DAHB98_0
(MELC
TYROSINASE)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		5 / 11 HIS B2946
HIS B3075
ASN B3076
HIS B3079
SER B3096
 CUO  B9008 (-3.1A)
CUO  B9008 (-2.8A)
None
CUO  B9008 (-3.5A)
CUO  B9008 ( 4.7A)
 0.48A 5z0jA-4bedB:
23.1
5z0jB-4bedB:
undetectable		 5z0jA-4bedB:
4.44
5z0jB-4bedB:
4.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z0K_B_DAHB98_0
(MELC
TYROSINASE)		 1js8 HEMOCYANIN
(Enteroctopus
dofleini) 		5 / 11 HIS A2543
HIS A2562
HIS A2671
ASN A2672
HIS A2675
 CUO  A 888 (-3.4A)
CUO  A 888 (-3.4A)
CUO  A 888 (-3.4A)
None
CUO  A 888 (-3.3A)
 0.54A 5z0kA-1js8A:
23.0
5z0kB-1js8A:
0.0		 5z0kA-1js8A:
9.57
5z0kB-1js8A:
11.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z0K_B_DAHB98_0
(MELC
TYROSINASE)		 1js8 HEMOCYANIN
(Enteroctopus
dofleini) 		5 / 11 HIS A2543
HIS A2571
HIS A2671
ASN A2672
HIS A2675
 CUO  A 888 (-3.4A)
CUO  A 888 (-3.3A)
CUO  A 888 (-3.4A)
None
CUO  A 888 (-3.3A)
 1.49A 5z0kA-1js8A:
23.0
5z0kB-1js8A:
0.0		 5z0kA-1js8A:
9.57
5z0kB-1js8A:
11.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z0K_B_DAHB98_0
(MELC
TYROSINASE)		 1js8 HEMOCYANIN
(Enteroctopus
dofleini) 		5 / 11 HIS A2562
HIS A2543
HIS A2675
HIS A2671
ASP A2706
 CUO  A 888 (-3.4A)
CUO  A 888 (-3.4A)
CUO  A 888 (-3.3A)
CUO  A 888 (-3.4A)
None
 1.41A 5z0kA-1js8A:
23.0
5z0kB-1js8A:
0.0		 5z0kA-1js8A:
9.57
5z0kB-1js8A:
11.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z0K_B_DAHB98_0
(MELC
TYROSINASE)		 3wky PROPHENOLOXIDASE B
(Marsupenaeus
japonicus) 		5 / 11 HIS A 199
HIS A 203
HIS A 357
ASN A 358
HIS A 361
 CUO  A 708 (-3.3A)
CUO  A 708 (-3.5A)
CUO  A 708 (-3.3A)
None
CUO  A 708 (-3.2A)
 0.72A 5z0kA-3wkyA:
10.5
5z0kB-3wkyA:
undetectable		 5z0kA-3wkyA:
8.13
5z0kB-3wkyA:
8.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z0K_B_DAHB98_0
(MELC
TYROSINASE)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		5 / 11 HIS A  42
HIS A  69
HIS A 179
ASN A 180
HIS A 183
 CUO  A9001 (-3.4A)
CUO  A9001 (-3.1A)
CUO  A9001 (-3.4A)
None
CUO  A9001 (-3.4A)
 1.46A 5z0kA-4bedA:
20.4
5z0kB-4bedA:
undetectable		 5z0kA-4bedA:
5.49
5z0kB-4bedA:
4.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z0K_B_DAHB98_0
(MELC
TYROSINASE)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		5 / 11 HIS A 462
HIS A 482
HIS A 602
ASN A 603
HIS A 606
 CUO  A9002 (-3.2A)
CUO  A9002 (-3.4A)
CUO  A9002 (-3.4A)
None
CUO  A9002 (-3.3A)
 1.00A 5z0kA-4bedA:
20.4
5z0kB-4bedA:
undetectable		 5z0kA-4bedA:
5.49
5z0kB-4bedA:
4.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z0K_B_DAHB98_0
(MELC
TYROSINASE)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		5 / 11 HIS A 462
HIS A 491
HIS A 602
ASN A 603
HIS A 606
 CUO  A9002 (-3.2A)
CUO  A9002 (-3.4A)
CUO  A9002 (-3.4A)
None
CUO  A9002 (-3.3A)
 1.45A 5z0kA-4bedA:
20.4
5z0kB-4bedA:
undetectable		 5z0kA-4bedA:
5.49
5z0kB-4bedA:
4.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z0K_B_DAHB98_0
(MELC
TYROSINASE)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		5 / 11 HIS A 876
HIS A 896
HIS A1015
ASN A1016
HIS A1019
 CUO  A9003 (-3.3A)
CUO  A9003 (-3.4A)
CUO  A9003 (-3.1A)
None
CUO  A9003 (-3.4A)
 1.04A 5z0kA-4bedA:
20.4
5z0kB-4bedA:
undetectable		 5z0kA-4bedA:
5.49
5z0kB-4bedA:
4.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z0K_B_DAHB98_0
(MELC
TYROSINASE)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		5 / 11 HIS B1705
HIS B1725
HIS B1847
ASN B1848
HIS B1851
 CUO  B9005 (-3.2A)
CUO  B9005 (-3.1A)
CUO  B9005 (-3.2A)
None
CUO  B9005 (-3.2A)
 0.84A 5z0kA-4bedB:
23.0
5z0kB-4bedB:
undetectable		 5z0kA-4bedB:
4.44
5z0kB-4bedB:
4.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z0K_B_DAHB98_0
(MELC
TYROSINASE)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		5 / 11 HIS B2122
HIS B2141
HIS B2260
ASN B2261
HIS B2264
 CUO  B9006 (-3.2A)
CUO  B9006 (-3.1A)
CUO  B9006 (-3.2A)
None
CUO  B9006 (-3.2A)
 0.92A 5z0kA-4bedB:
23.0
5z0kB-4bedB:
undetectable		 5z0kA-4bedB:
4.44
5z0kB-4bedB:
4.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z0K_B_DAHB98_0
(MELC
TYROSINASE)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		5 / 11 HIS B2946
HIS B2965
HIS B3075
HIS B3079
SER B3096
 CUO  B9008 (-3.1A)
CUO  B9008 (-3.2A)
CUO  B9008 (-2.8A)
CUO  B9008 (-3.5A)
CUO  B9008 ( 4.7A)
 0.73A 5z0kA-4bedB:
23.0
5z0kB-4bedB:
undetectable		 5z0kA-4bedB:
4.44
5z0kB-4bedB:
4.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z0K_B_DAHB98_0
(MELC
TYROSINASE)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		5 / 11 HIS B2946
HIS B3075
ASN B3076
HIS B3079
SER B3096
 CUO  B9008 (-3.1A)
CUO  B9008 (-2.8A)
None
CUO  B9008 (-3.5A)
CUO  B9008 ( 4.7A)
 0.47A 5z0kA-4bedB:
23.0
5z0kB-4bedB:
undetectable		 5z0kA-4bedB:
4.44
5z0kB-4bedB:
4.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z0L_B_DAHB98_0
(MELC
TYROSINASE)		 1js8 HEMOCYANIN
(Enteroctopus
dofleini) 		5 / 11 HIS A2543
HIS A2562
HIS A2671
ASN A2672
HIS A2675
 CUO  A 888 (-3.4A)
CUO  A 888 (-3.4A)
CUO  A 888 (-3.4A)
None
CUO  A 888 (-3.3A)
 0.53A 5z0lA-1js8A:
23.1
5z0lB-1js8A:
0.0		 5z0lA-1js8A:
9.57
5z0lB-1js8A:
11.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z0L_B_DAHB98_0
(MELC
TYROSINASE)		 1js8 HEMOCYANIN
(Enteroctopus
dofleini) 		5 / 11 HIS A2543
HIS A2571
HIS A2671
ASN A2672
HIS A2675
 CUO  A 888 (-3.4A)
CUO  A 888 (-3.3A)
CUO  A 888 (-3.4A)
None
CUO  A 888 (-3.3A)
 1.43A 5z0lA-1js8A:
23.1
5z0lB-1js8A:
0.0		 5z0lA-1js8A:
9.57
5z0lB-1js8A:
11.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z0L_B_DAHB98_0
(MELC
TYROSINASE)		 3wky PROPHENOLOXIDASE B
(Marsupenaeus
japonicus) 		5 / 11 HIS A 199
HIS A 203
HIS A 357
ASN A 358
HIS A 361
 CUO  A 708 (-3.3A)
CUO  A 708 (-3.5A)
CUO  A 708 (-3.3A)
None
CUO  A 708 (-3.2A)
 0.75A 5z0lA-3wkyA:
10.5
5z0lB-3wkyA:
undetectable		 5z0lA-3wkyA:
8.13
5z0lB-3wkyA:
8.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z0L_B_DAHB98_0
(MELC
TYROSINASE)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		5 / 11 HIS A  42
HIS A  69
HIS A 179
ASN A 180
HIS A 183
 CUO  A9001 (-3.4A)
CUO  A9001 (-3.1A)
CUO  A9001 (-3.4A)
None
CUO  A9001 (-3.4A)
 1.42A 5z0lA-4bedA:
20.6
5z0lB-4bedA:
undetectable		 5z0lA-4bedA:
5.49
5z0lB-4bedA:
4.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z0L_B_DAHB98_0
(MELC
TYROSINASE)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		5 / 11 HIS A 462
HIS A 482
HIS A 602
ASN A 603
HIS A 606
 CUO  A9002 (-3.2A)
CUO  A9002 (-3.4A)
CUO  A9002 (-3.4A)
None
CUO  A9002 (-3.3A)
 1.02A 5z0lA-4bedA:
20.6
5z0lB-4bedA:
undetectable		 5z0lA-4bedA:
5.49
5z0lB-4bedA:
4.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z0L_B_DAHB98_0
(MELC
TYROSINASE)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		5 / 11 HIS A 462
HIS A 491
HIS A 602
ASN A 603
HIS A 606
 CUO  A9002 (-3.2A)
CUO  A9002 (-3.4A)
CUO  A9002 (-3.4A)
None
CUO  A9002 (-3.3A)
 1.40A 5z0lA-4bedA:
20.6
5z0lB-4bedA:
undetectable		 5z0lA-4bedA:
5.49
5z0lB-4bedA:
4.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z0L_B_DAHB98_0
(MELC
TYROSINASE)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		5 / 11 HIS B1705
HIS B1725
HIS B1847
ASN B1848
HIS B1851
 CUO  B9005 (-3.2A)
CUO  B9005 (-3.1A)
CUO  B9005 (-3.2A)
None
CUO  B9005 (-3.2A)
 0.85A 5z0lA-4bedB:
23.1
5z0lB-4bedB:
undetectable		 5z0lA-4bedB:
4.44
5z0lB-4bedB:
4.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z0L_B_DAHB98_0
(MELC
TYROSINASE)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		5 / 11 HIS B1705
HIS B1734
HIS B1847
ASN B1848
HIS B1851
 CUO  B9005 (-3.2A)
CUO  B9005 (-3.4A)
CUO  B9005 (-3.2A)
None
CUO  B9005 (-3.2A)
 1.48A 5z0lA-4bedB:
23.1
5z0lB-4bedB:
undetectable		 5z0lA-4bedB:
4.44
5z0lB-4bedB:
4.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z0L_B_DAHB98_0
(MELC
TYROSINASE)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		5 / 11 HIS B2542
HIS B2570
HIS B2670
ASN B2671
HIS B2674
 CUO  B9007 (-3.3A)
CUO  B9007 (-3.3A)
CUO  B9007 (-3.4A)
None
CUO  B9007 (-3.4A)
 1.48A 5z0lA-4bedB:
23.1
5z0lB-4bedB:
undetectable		 5z0lA-4bedB:
4.44
5z0lB-4bedB:
4.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z0L_B_DAHB98_0
(MELC
TYROSINASE)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		5 / 11 HIS B2946
HIS B2965
HIS B3075
HIS B3079
SER B3096
 CUO  B9008 (-3.1A)
CUO  B9008 (-3.2A)
CUO  B9008 (-2.8A)
CUO  B9008 (-3.5A)
CUO  B9008 ( 4.7A)
 0.76A 5z0lA-4bedB:
23.1
5z0lB-4bedB:
undetectable		 5z0lA-4bedB:
4.44
5z0lB-4bedB:
4.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z0L_B_DAHB98_0
(MELC
TYROSINASE)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		5 / 11 HIS B2946
HIS B2974
ASN B3076
HIS B3079
SER B3096
 CUO  B9008 (-3.1A)
CUO  B9008 (-2.9A)
None
CUO  B9008 (-3.5A)
CUO  B9008 ( 4.7A)
 1.43A 5z0lA-4bedB:
23.1
5z0lB-4bedB:
undetectable		 5z0lA-4bedB:
4.44
5z0lB-4bedB:
4.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z0L_B_DAHB98_0
(MELC
TYROSINASE)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		5 / 11 HIS B2946
HIS B3075
ASN B3076
HIS B3079
SER B3096
 CUO  B9008 (-3.1A)
CUO  B9008 (-2.8A)
None
CUO  B9008 (-3.5A)
CUO  B9008 ( 4.7A)
 0.44A 5z0lA-4bedB:
23.1
5z0lB-4bedB:
undetectable		 5z0lA-4bedB:
4.44
5z0lB-4bedB:
4.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z0M_B_DAHB98_0
(MELC
TYROSINASE)		 1js8 HEMOCYANIN
(Enteroctopus
dofleini) 		5 / 11 HIS A2543
HIS A2562
HIS A2671
ASN A2672
HIS A2675
 CUO  A 888 (-3.4A)
CUO  A 888 (-3.4A)
CUO  A 888 (-3.4A)
None
CUO  A 888 (-3.3A)
 0.51A 5z0mA-1js8A:
23.0
5z0mB-1js8A:
0.0		 5z0mA-1js8A:
12.50
5z0mB-1js8A:
11.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z0M_B_DAHB98_0
(MELC
TYROSINASE)		 1js8 HEMOCYANIN
(Enteroctopus
dofleini) 		5 / 11 HIS A2543
HIS A2571
HIS A2671
ASN A2672
HIS A2675
 CUO  A 888 (-3.4A)
CUO  A 888 (-3.3A)
CUO  A 888 (-3.4A)
None
CUO  A 888 (-3.3A)
 1.32A 5z0mA-1js8A:
23.0
5z0mB-1js8A:
0.0		 5z0mA-1js8A:
12.50
5z0mB-1js8A:
11.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z0M_B_DAHB98_0
(MELC
TYROSINASE)		 3wky PROPHENOLOXIDASE B
(Marsupenaeus
japonicus) 		5 / 11 HIS A 199
HIS A 203
HIS A 357
ASN A 358
HIS A 361
 CUO  A 708 (-3.3A)
CUO  A 708 (-3.5A)
CUO  A 708 (-3.3A)
None
CUO  A 708 (-3.2A)
 0.81A 5z0mA-3wkyA:
10.4
5z0mB-3wkyA:
undetectable		 5z0mA-3wkyA:
8.43
5z0mB-3wkyA:
8.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z0M_B_DAHB98_0
(MELC
TYROSINASE)		 3wky PROPHENOLOXIDASE B
(Marsupenaeus
japonicus) 		5 / 11 HIS A 357
HIS A 226
HIS A 199
VAL A 380
ASP A 390
 CUO  A 708 (-3.3A)
CUO  A 708 (-3.3A)
CUO  A 708 (-3.3A)
None
None
 1.39A 5z0mA-3wkyA:
10.4
5z0mB-3wkyA:
undetectable		 5z0mA-3wkyA:
8.43
5z0mB-3wkyA:
8.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z0M_B_DAHB98_0
(MELC
TYROSINASE)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		5 / 11 HIS A  42
HIS A  60
HIS A 179
ASN A 180
HIS A 183
 CUO  A9001 (-3.4A)
CUO  A9001 (-3.1A)
CUO  A9001 (-3.4A)
None
CUO  A9001 (-3.4A)
 1.06A 5z0mA-4bedA:
20.4
5z0mB-4bedA:
undetectable		 5z0mA-4bedA:
5.15
5z0mB-4bedA:
4.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z0M_B_DAHB98_0
(MELC
TYROSINASE)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		5 / 11 HIS A  42
HIS A  69
HIS A 179
ASN A 180
HIS A 183
 CUO  A9001 (-3.4A)
CUO  A9001 (-3.1A)
CUO  A9001 (-3.4A)
None
CUO  A9001 (-3.4A)
 1.31A 5z0mA-4bedA:
20.4
5z0mB-4bedA:
undetectable		 5z0mA-4bedA:
5.15
5z0mB-4bedA:
4.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z0M_B_DAHB98_0
(MELC
TYROSINASE)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		5 / 11 HIS A 462
HIS A 482
HIS A 602
ASN A 603
HIS A 606
 CUO  A9002 (-3.2A)
CUO  A9002 (-3.4A)
CUO  A9002 (-3.4A)
None
CUO  A9002 (-3.3A)
 1.07A 5z0mA-4bedA:
20.4
5z0mB-4bedA:
undetectable		 5z0mA-4bedA:
5.15
5z0mB-4bedA:
4.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z0M_B_DAHB98_0
(MELC
TYROSINASE)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		5 / 11 HIS A 462
HIS A 491
HIS A 602
ASN A 603
HIS A 606
 CUO  A9002 (-3.2A)
CUO  A9002 (-3.4A)
CUO  A9002 (-3.4A)
None
CUO  A9002 (-3.3A)
 1.31A 5z0mA-4bedA:
20.4
5z0mB-4bedA:
undetectable		 5z0mA-4bedA:
5.15
5z0mB-4bedA:
4.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z0M_B_DAHB98_0
(MELC
TYROSINASE)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		5 / 11 HIS B1705
HIS B1725
HIS B1847
ASN B1848
HIS B1851
 CUO  B9005 (-3.2A)
CUO  B9005 (-3.1A)
CUO  B9005 (-3.2A)
None
CUO  B9005 (-3.2A)
 0.88A 5z0mA-4bedB:
23.0
5z0mB-4bedB:
undetectable		 5z0mA-4bedB:
4.32
5z0mB-4bedB:
4.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z0M_B_DAHB98_0
(MELC
TYROSINASE)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		5 / 11 HIS B1705
HIS B1734
HIS B1847
ASN B1848
HIS B1851
 CUO  B9005 (-3.2A)
CUO  B9005 (-3.4A)
CUO  B9005 (-3.2A)
None
CUO  B9005 (-3.2A)
 1.37A 5z0mA-4bedB:
23.0
5z0mB-4bedB:
undetectable		 5z0mA-4bedB:
4.32
5z0mB-4bedB:
4.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z0M_B_DAHB98_0
(MELC
TYROSINASE)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		5 / 11 HIS B2542
HIS B2561
HIS B2670
ASN B2671
HIS B2674
 CUO  B9007 (-3.3A)
CUO  B9007 (-3.3A)
CUO  B9007 (-3.4A)
None
CUO  B9007 (-3.4A)
 0.92A 5z0mA-4bedB:
23.0
5z0mB-4bedB:
undetectable		 5z0mA-4bedB:
4.32
5z0mB-4bedB:
4.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z0M_B_DAHB98_0
(MELC
TYROSINASE)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		5 / 11 HIS B2542
HIS B2570
HIS B2670
ASN B2671
HIS B2674
 CUO  B9007 (-3.3A)
CUO  B9007 (-3.3A)
CUO  B9007 (-3.4A)
None
CUO  B9007 (-3.4A)
 1.38A 5z0mA-4bedB:
23.0
5z0mB-4bedB:
undetectable		 5z0mA-4bedB:
4.32
5z0mB-4bedB:
4.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z0M_B_DAHB98_0
(MELC
TYROSINASE)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		5 / 11 HIS B2946
HIS B2965
HIS B3075
HIS B3079
SER B3096
 CUO  B9008 (-3.1A)
CUO  B9008 (-3.2A)
CUO  B9008 (-2.8A)
CUO  B9008 (-3.5A)
CUO  B9008 ( 4.7A)
 0.75A 5z0mA-4bedB:
23.0
5z0mB-4bedB:
undetectable		 5z0mA-4bedB:
4.32
5z0mB-4bedB:
4.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z0M_B_DAHB98_0
(MELC
TYROSINASE)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		6 / 11 HIS B2946
HIS B2974
HIS B3075
ASN B3076
HIS B3079
SER B3096
 CUO  B9008 (-3.1A)
CUO  B9008 (-2.9A)
CUO  B9008 (-2.8A)
None
CUO  B9008 (-3.5A)
CUO  B9008 ( 4.7A)
 1.28A 5z0mA-4bedB:
23.0
5z0mB-4bedB:
undetectable		 5z0mA-4bedB:
4.32
5z0mB-4bedB:
4.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z0M_B_DAHB98_0
(MELC
TYROSINASE)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		5 / 11 HIS B3079
HIS B3075
HIS B2974
HIS B2946
SER B3096
 CUO  B9008 (-3.5A)
CUO  B9008 (-2.8A)
CUO  B9008 (-2.9A)
CUO  B9008 (-3.1A)
CUO  B9008 ( 4.7A)
 1.39A 5z0mA-4bedB:
23.0
5z0mB-4bedB:
undetectable		 5z0mA-4bedB:
4.32
5z0mB-4bedB:
4.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z84_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		3 / 3 HIS B2946
HIS B3106
HIS B2974
 CUO  B9008 (-3.1A)
CUO  B9008 (-3.3A)
CUO  B9008 (-2.9A)
 0.75A 5z84A-4bedB:
undetectable		 5z84A-4bedB:
14.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z84_N_CUN604_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		3 / 3 HIS B2946
HIS B3106
HIS B2974
 CUO  B9008 (-3.1A)
CUO  B9008 (-3.3A)
CUO  B9008 (-2.9A)
 0.76A 5z84N-4bedB:
0.4		 5z84N-4bedB:
14.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z85_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		3 / 3 HIS B2946
HIS B3106
HIS B2974
 CUO  B9008 (-3.1A)
CUO  B9008 (-3.3A)
CUO  B9008 (-2.9A)
 0.76A 5z85A-4bedB:
undetectable		 5z85A-4bedB:
14.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z86_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		3 / 3 HIS B2946
HIS B3106
HIS B2974
 CUO  B9008 (-3.1A)
CUO  B9008 (-3.3A)
CUO  B9008 (-2.9A)
 0.75A 5z86A-4bedB:
undetectable		 5z86A-4bedB:
14.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z86_N_CUN603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		3 / 3 HIS B2946
HIS B3106
HIS B2974
 CUO  B9008 (-3.1A)
CUO  B9008 (-3.3A)
CUO  B9008 (-2.9A)
 0.78A 5z86N-4bedB:
undetectable		 5z86N-4bedB:
14.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCO_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		3 / 3 HIS B2946
HIS B3106
HIS B2974
 CUO  B9008 (-3.1A)
CUO  B9008 (-3.3A)
CUO  B9008 (-2.9A)
 0.73A 5zcoA-4bedB:
undetectable		 5zcoA-4bedB:
14.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCO_N_CUN604_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		3 / 3 HIS B2946
HIS B3106
HIS B2974
 CUO  B9008 (-3.1A)
CUO  B9008 (-3.3A)
CUO  B9008 (-2.9A)
 0.73A 5zcoN-4bedB:
undetectable		 5zcoN-4bedB:
14.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCP_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		3 / 3 HIS B2946
HIS B3106
HIS B2974
 CUO  B9008 (-3.1A)
CUO  B9008 (-3.3A)
CUO  B9008 (-2.9A)
 0.73A 5zcpA-4bedB:
undetectable		 5zcpA-4bedB:
14.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCP_N_CUN604_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		3 / 3 HIS B2946
HIS B3106
HIS B2974
 CUO  B9008 (-3.1A)
CUO  B9008 (-3.3A)
CUO  B9008 (-2.9A)
 0.76A 5zcpN-4bedB:
0.3		 5zcpN-4bedB:
14.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCQ_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		3 / 3 HIS B2946
HIS B3106
HIS B2974
 CUO  B9008 (-3.1A)
CUO  B9008 (-3.3A)
CUO  B9008 (-2.9A)
 0.73A 5zcqA-4bedB:
undetectable		 5zcqA-4bedB:
14.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCQ_N_CUN603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		3 / 3 HIS B2946
HIS B3106
HIS B2974
 CUO  B9008 (-3.1A)
CUO  B9008 (-3.3A)
CUO  B9008 (-2.9A)
 0.74A 5zcqN-4bedB:
0.4		 5zcqN-4bedB:
14.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZRD_A_CUA606_0
(TYROSINASE)		 1js8 HEMOCYANIN
(Enteroctopus
dofleini) 		4 / 4 HIS A2543
CYH A2560
HIS A2562
HIS A2571
 CUO  A 888 (-3.4A)
CUO  A 888 ( 3.8A)
CUO  A 888 (-3.4A)
CUO  A 888 (-3.3A)
 0.24A 5zrdA-1js8A:
27.5		 5zrdA-1js8A:
24.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZRD_A_CUA606_0
(TYROSINASE)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		4 / 4 HIS A  42
CYH A  58
HIS A  60
HIS A  69
 CUO  A9001 (-3.4A)
CUO  A9001 ( 4.2A)
CUO  A9001 (-3.1A)
CUO  A9001 (-3.1A)
 0.50A 5zrdA-4bedA:
10.3		 5zrdA-4bedA:
16.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZRD_A_CUA606_0
(TYROSINASE)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		4 / 4 HIS A 462
CYH A 480
HIS A 482
HIS A 491
 CUO  A9002 (-3.2A)
CUO  A9002 (-3.2A)
CUO  A9002 (-3.4A)
CUO  A9002 (-3.4A)
 0.96A 5zrdA-4bedA:
10.3		 5zrdA-4bedA:
16.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZRD_A_CUA606_0
(TYROSINASE)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		4 / 4 HIS A 482
CYH A 480
HIS A 491
HIS A 462
 CUO  A9002 (-3.4A)
CUO  A9002 (-3.2A)
CUO  A9002 (-3.4A)
CUO  A9002 (-3.2A)
 1.09A 5zrdA-4bedA:
10.3		 5zrdA-4bedA:
16.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZRD_A_CUA606_0
(TYROSINASE)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		4 / 4 HIS A 491
CYH A 480
HIS A 462
HIS A 482
 CUO  A9002 (-3.4A)
CUO  A9002 (-3.2A)
CUO  A9002 (-3.2A)
CUO  A9002 (-3.4A)
 1.21A 5zrdA-4bedA:
10.3		 5zrdA-4bedA:
16.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZRD_A_CUA606_0
(TYROSINASE)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		4 / 4 HIS A 876
CYH A 894
HIS A 896
HIS A 905
 CUO  A9003 (-3.3A)
CUO  A9003 (-3.1A)
CUO  A9003 (-3.4A)
CUO  A9003 (-3.5A)
 0.94A 5zrdA-4bedA:
10.3		 5zrdA-4bedA:
16.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZRD_A_CUA606_0
(TYROSINASE)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		4 / 4 HIS A 896
CYH A 894
HIS A 905
HIS A 876
 CUO  A9003 (-3.4A)
CUO  A9003 (-3.1A)
CUO  A9003 (-3.5A)
CUO  A9003 (-3.3A)
 1.07A 5zrdA-4bedA:
10.3		 5zrdA-4bedA:
16.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZRD_A_CUA606_0
(TYROSINASE)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		4 / 4 HIS A 905
CYH A 894
HIS A 876
HIS A 896
 CUO  A9003 (-3.5A)
CUO  A9003 (-3.1A)
CUO  A9003 (-3.3A)
CUO  A9003 (-3.4A)
 1.28A 5zrdA-4bedA:
10.3		 5zrdA-4bedA:
16.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZRD_A_CUA606_0
(TYROSINASE)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		4 / 4 HIS A1293
CYH A1309
HIS A1311
HIS A1320
 CUO  A9004 (-3.2A)
CUO  A9004 ( 3.9A)
CUO  A9004 (-3.4A)
CUO  A9004 (-3.5A)
 0.90A 5zrdA-4bedA:
10.3		 5zrdA-4bedA:
16.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZRD_A_CUA606_0
(TYROSINASE)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		4 / 4 HIS A1320
CYH A1309
HIS A1293
HIS A1311
 CUO  A9004 (-3.5A)
CUO  A9004 ( 3.9A)
CUO  A9004 (-3.2A)
CUO  A9004 (-3.4A)
 1.13A 5zrdA-4bedA:
10.3		 5zrdA-4bedA:
16.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZRD_A_CUA606_0
(TYROSINASE)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		4 / 4 HIS B2122
CYH B2139
HIS B2141
HIS B2150
 CUO  B9006 (-3.2A)
CUO  B9006 (-3.6A)
CUO  B9006 (-3.1A)
CUO  B9006 (-3.3A)
 1.14A 5zrdA-4bedB:
30.3		 5zrdA-4bedB:
15.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZRD_A_CUA606_0
(TYROSINASE)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		4 / 4 HIS B2141
CYH B2139
HIS B2150
HIS B2122
 CUO  B9006 (-3.1A)
CUO  B9006 (-3.6A)
CUO  B9006 (-3.3A)
CUO  B9006 (-3.2A)
 1.02A 5zrdA-4bedB:
30.3		 5zrdA-4bedB:
15.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZRD_A_CUA606_0
(TYROSINASE)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		4 / 4 HIS B2570
CYH B2559
HIS B2542
HIS B2561
 CUO  B9007 (-3.3A)
CUO  B9007 ( 3.7A)
CUO  B9007 (-3.3A)
CUO  B9007 (-3.3A)
 1.09A 5zrdA-4bedB:
30.3		 5zrdA-4bedB:
15.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZRD_A_CUA606_0
(TYROSINASE)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		4 / 4 HIS B2946
CYH B2963
HIS B2965
HIS B2974
 CUO  B9008 (-3.1A)
CUO  B9008 (-3.0A)
CUO  B9008 (-3.2A)
CUO  B9008 (-2.9A)
 0.74A 5zrdA-4bedB:
30.3		 5zrdA-4bedB:
15.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZRD_A_CUA607_0
(TYROSINASE)		 1js8 HEMOCYANIN
(Enteroctopus
dofleini) 		3 / 3 HIS A2671
HIS A2675
HIS A2702
 CUO  A 888 (-3.4A)
CUO  A 888 (-3.3A)
CUO  A 888 (-3.3A)
 0.19A 5zrdA-1js8A:
27.6		 5zrdA-1js8A:
24.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZRD_A_CUA607_0
(TYROSINASE)		 3wky PROPHENOLOXIDASE B
(Marsupenaeus
japonicus) 		3 / 3 HIS A 357
HIS A 361
HIS A 397
 CUO  A 708 (-3.3A)
CUO  A 708 (-3.2A)
CUO  A 708 (-3.4A)
 0.16A 5zrdA-3wkyA:
8.7		 5zrdA-3wkyA:
22.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZRD_A_CUA607_0
(TYROSINASE)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		3 / 3 HIS B3106
HIS B2974
HIS B3075
 CUO  B9008 (-3.3A)
CUO  B9008 (-2.9A)
CUO  B9008 (-2.8A)
 0.55A 5zrdA-4bedB:
30.3		 5zrdA-4bedB:
15.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZRD_B_CUB606_0
(TYROSINASE)		 1js8 HEMOCYANIN
(Enteroctopus
dofleini) 		5 / 5 HIS A2671
HIS A2675
PHE A2698
HIS A2701
HIS A2702
 CUO  A 888 (-3.4A)
CUO  A 888 (-3.3A)
None
None
CUO  A 888 (-3.3A)
 0.36A 5zrdB-1js8A:
4.5		 5zrdB-1js8A:
24.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZRD_B_CUB606_0
(TYROSINASE)		 3wky PROPHENOLOXIDASE B
(Marsupenaeus
japonicus) 		4 / 5 HIS A 199
HIS A 203
PHE A 222
HIS A 226
 CUO  A 708 (-3.3A)
CUO  A 708 (-3.5A)
None
CUO  A 708 (-3.3A)
 0.79A 5zrdB-3wkyA:
3.6		 5zrdB-3wkyA:
22.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZRD_B_CUB606_0
(TYROSINASE)		 3wky PROPHENOLOXIDASE B
(Marsupenaeus
japonicus) 		4 / 5 HIS A 357
HIS A 361
PHE A 393
HIS A 397
 CUO  A 708 (-3.3A)
CUO  A 708 (-3.2A)
CUO  A 708 (-4.5A)
CUO  A 708 (-3.4A)
 0.24A 5zrdB-3wkyA:
3.6		 5zrdB-3wkyA:
22.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZRD_B_CUB606_0
(TYROSINASE)		 3wky PROPHENOLOXIDASE B
(Marsupenaeus
japonicus) 		4 / 5 HIS A 397
HIS A 357
PHE A  72
HIS A 361
 CUO  A 708 (-3.4A)
CUO  A 708 (-3.3A)
CUO  A 708 (-4.6A)
CUO  A 708 (-3.2A)
 1.04A 5zrdB-3wkyA:
3.6		 5zrdB-3wkyA:
22.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZRD_B_CUB606_0
(TYROSINASE)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		5 / 5 HIS A 179
HIS A 183
PHE A 206
HIS A 209
HIS A 210
 CUO  A9001 (-3.4A)
CUO  A9001 (-3.4A)
CUO  A9001 (-4.6A)
None
CUO  A9001 (-3.3A)
 0.78A 5zrdB-4bedA:
2.7		 5zrdB-4bedA:
16.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZRD_B_CUB606_0
(TYROSINASE)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		5 / 5 HIS A 602
HIS A 606
PHE A 629
HIS A 632
HIS A 633
 CUO  A9002 (-3.4A)
CUO  A9002 (-3.3A)
CUO  A9002 (-4.3A)
None
CUO  A9002 (-3.3A)
 0.93A 5zrdB-4bedA:
2.7		 5zrdB-4bedA:
16.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZRD_B_CUB606_0
(TYROSINASE)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		5 / 5 HIS A1015
HIS A1019
PHE A1042
HIS A1045
HIS A1046
 CUO  A9003 (-3.1A)
CUO  A9003 (-3.4A)
CUO  A9003 ( 4.9A)
None
CUO  A9003 (-3.2A)
 0.82A 5zrdB-4bedA:
2.7		 5zrdB-4bedA:
16.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZRD_B_CUB606_0
(TYROSINASE)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		4 / 5 HIS A1046
HIS A 905
HIS A1015
HIS A1019
 CUO  A9003 (-3.2A)
CUO  A9003 (-3.5A)
CUO  A9003 (-3.1A)
CUO  A9003 (-3.4A)
 1.01A 5zrdB-4bedA:
2.7		 5zrdB-4bedA:
16.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZRD_B_CUB606_0
(TYROSINASE)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		5 / 5 HIS A1424
HIS A1428
PHE A1451
HIS A1454
HIS A1455
 CUO  A9004 (-3.0A)
CUO  A9004 (-3.4A)
CUO  A9004 (-4.5A)
None
CUO  A9004 (-3.3A)
 0.84A 5zrdB-4bedA:
2.7		 5zrdB-4bedA:
16.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZRD_B_CUB606_0
(TYROSINASE)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		4 / 5 HIS B1705
HIS B1725
PHE B1730
HIS B1734
 CUO  B9005 (-3.2A)
CUO  B9005 (-3.1A)
CUO  B9005 ( 4.9A)
CUO  B9005 (-3.4A)
 0.95A 5zrdB-4bedB:
28.1		 5zrdB-4bedB:
15.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZRD_B_CUB606_0
(TYROSINASE)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		5 / 5 HIS B1847
HIS B1851
PHE B1874
HIS B1877
HIS B1878
 CUO  B9005 (-3.2A)
CUO  B9005 (-3.2A)
CUO  B9005 (-4.4A)
None
CUO  B9005 (-3.3A)
 0.85A 5zrdB-4bedB:
28.1		 5zrdB-4bedB:
15.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZRD_B_CUB606_0
(TYROSINASE)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		4 / 5 HIS B2122
HIS B2141
PHE B2146
HIS B2150
 CUO  B9006 (-3.2A)
CUO  B9006 (-3.1A)
CUO  B9006 (-4.7A)
CUO  B9006 (-3.3A)
 0.93A 5zrdB-4bedB:
28.1		 5zrdB-4bedB:
15.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZRD_B_CUB606_0
(TYROSINASE)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		5 / 5 HIS B2260
HIS B2264
PHE B2287
HIS B2290
HIS B2291
 CUO  B9006 (-3.2A)
CUO  B9006 (-3.2A)
CUO  B9006 (-4.7A)
None
CUO  B9006 (-3.5A)
 0.87A 5zrdB-4bedB:
28.1		 5zrdB-4bedB:
15.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZRD_B_CUB606_0
(TYROSINASE)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		4 / 5 HIS B2291
HIS B2150
HIS B2260
HIS B2264
 CUO  B9006 (-3.5A)
CUO  B9006 (-3.3A)
CUO  B9006 (-3.2A)
CUO  B9006 (-3.2A)
 0.90A 5zrdB-4bedB:
28.1		 5zrdB-4bedB:
15.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZRD_B_CUB606_0
(TYROSINASE)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		5 / 5 HIS B2670
HIS B2674
PHE B2697
HIS B2700
HIS B2701
 CUO  B9007 (-3.4A)
CUO  B9007 (-3.4A)
CUO  B9007 (-4.7A)
None
CUO  B9007 (-3.1A)
 0.82A 5zrdB-4bedB:
28.1		 5zrdB-4bedB:
15.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZRD_B_CUB606_0
(TYROSINASE)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		4 / 5 HIS B3075
HIS B3079
PHE B3102
HIS B3105
 CUO  B9008 (-2.8A)
CUO  B9008 (-3.5A)
CUO  B9008 (-4.7A)
None
 0.60A 5zrdB-4bedB:
28.1		 5zrdB-4bedB:
15.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZRD_B_CUB606_0
(TYROSINASE)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		4 / 5 HIS B3075
HIS B3079
PHE B3102
HIS B3106
 CUO  B9008 (-2.8A)
CUO  B9008 (-3.5A)
CUO  B9008 (-4.7A)
CUO  B9008 (-3.3A)
 0.54A 5zrdB-4bedB:
28.1		 5zrdB-4bedB:
15.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZRD_B_CUB607_0
(TYROSINASE)		 1js8 HEMOCYANIN
(Enteroctopus
dofleini) 		5 / 5 HIS A2543
CYH A2560
HIS A2562
HIS A2571
PHE A2698
 CUO  A 888 (-3.4A)
CUO  A 888 ( 3.8A)
CUO  A 888 (-3.4A)
CUO  A 888 (-3.3A)
None
 0.44A 5zrdB-1js8A:
4.5		 5zrdB-1js8A:
24.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZRD_B_CUB607_0
(TYROSINASE)		 1js8 HEMOCYANIN
(Enteroctopus
dofleini) 		4 / 5 HIS A2671
HIS A2675
HIS A2702
PHE A2567
 CUO  A 888 (-3.4A)
CUO  A 888 (-3.3A)
CUO  A 888 (-3.3A)
CUO  A 888 (-4.8A)
 0.91A 5zrdB-1js8A:
4.5		 5zrdB-1js8A:
24.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZRD_B_CUB607_0
(TYROSINASE)		 3wky PROPHENOLOXIDASE B
(Marsupenaeus
japonicus) 		4 / 5 HIS A 199
HIS A 203
HIS A 226
PHE A 393
 CUO  A 708 (-3.3A)
CUO  A 708 (-3.5A)
CUO  A 708 (-3.3A)
CUO  A 708 (-4.5A)
 0.74A 5zrdB-3wkyA:
3.6		 5zrdB-3wkyA:
22.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZRD_B_CUB607_0
(TYROSINASE)		 3wky PROPHENOLOXIDASE B
(Marsupenaeus
japonicus) 		4 / 5 HIS A 203
HIS A 226
HIS A 199
PHE A  72
 CUO  A 708 (-3.5A)
CUO  A 708 (-3.3A)
CUO  A 708 (-3.3A)
CUO  A 708 (-4.6A)
 1.21A 5zrdB-3wkyA:
3.6		 5zrdB-3wkyA:
22.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZRD_B_CUB607_0
(TYROSINASE)		 3wky PROPHENOLOXIDASE B
(Marsupenaeus
japonicus) 		4 / 5 HIS A 357
HIS A 361
HIS A 397
PHE A 222
 CUO  A 708 (-3.3A)
CUO  A 708 (-3.2A)
CUO  A 708 (-3.4A)
None
 0.95A 5zrdB-3wkyA:
3.6		 5zrdB-3wkyA:
22.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZRD_B_CUB607_0
(TYROSINASE)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		5 / 5 HIS A  42
CYH A  58
HIS A  60
HIS A  69
PHE A 206
 CUO  A9001 (-3.4A)
CUO  A9001 ( 4.2A)
CUO  A9001 (-3.1A)
CUO  A9001 (-3.1A)
CUO  A9001 (-4.6A)
 0.52A 5zrdB-4bedA:
2.7		 5zrdB-4bedA:
16.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZRD_B_CUB607_0
(TYROSINASE)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		5 / 5 HIS A 462
CYH A 480
HIS A 482
HIS A 491
PHE A 629
 CUO  A9002 (-3.2A)
CUO  A9002 (-3.2A)
CUO  A9002 (-3.4A)
CUO  A9002 (-3.4A)
CUO  A9002 (-4.3A)
 0.86A 5zrdB-4bedA:
2.7		 5zrdB-4bedA:
16.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZRD_B_CUB607_0
(TYROSINASE)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		4 / 5 HIS A 482
CYH A 480
HIS A 491
HIS A 462
 CUO  A9002 (-3.4A)
CUO  A9002 (-3.2A)
CUO  A9002 (-3.4A)
CUO  A9002 (-3.2A)
 1.00A 5zrdB-4bedA:
2.7		 5zrdB-4bedA:
16.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZRD_B_CUB607_0
(TYROSINASE)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		4 / 5 HIS A 491
CYH A 480
HIS A 462
HIS A 482
 CUO  A9002 (-3.4A)
CUO  A9002 (-3.2A)
CUO  A9002 (-3.2A)
CUO  A9002 (-3.4A)
 1.15A 5zrdB-4bedA:
2.7		 5zrdB-4bedA:
16.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZRD_B_CUB607_0
(TYROSINASE)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		5 / 5 HIS A 876
CYH A 894
HIS A 896
HIS A 905
PHE A1042
 CUO  A9003 (-3.3A)
CUO  A9003 (-3.1A)
CUO  A9003 (-3.4A)
CUO  A9003 (-3.5A)
CUO  A9003 ( 4.9A)
 0.86A 5zrdB-4bedA:
2.7		 5zrdB-4bedA:
16.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZRD_B_CUB607_0
(TYROSINASE)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		4 / 5 HIS A 896
CYH A 894
HIS A 905
HIS A 876
 CUO  A9003 (-3.4A)
CUO  A9003 (-3.1A)
CUO  A9003 (-3.5A)
CUO  A9003 (-3.3A)
 0.99A 5zrdB-4bedA:
2.7		 5zrdB-4bedA:
16.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZRD_B_CUB607_0
(TYROSINASE)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		4 / 5 HIS A 905
CYH A 894
HIS A 876
HIS A 896
 CUO  A9003 (-3.5A)
CUO  A9003 (-3.1A)
CUO  A9003 (-3.3A)
CUO  A9003 (-3.4A)
 1.22A 5zrdB-4bedA:
2.7		 5zrdB-4bedA:
16.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZRD_B_CUB607_0
(TYROSINASE)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		5 / 5 HIS A1293
CYH A1309
HIS A1311
HIS A1320
PHE A1451
 CUO  A9004 (-3.2A)
CUO  A9004 ( 3.9A)
CUO  A9004 (-3.4A)
CUO  A9004 (-3.5A)
CUO  A9004 (-4.5A)
 0.80A 5zrdB-4bedA:
2.7		 5zrdB-4bedA:
16.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZRD_B_CUB607_0
(TYROSINASE)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		4 / 5 HIS A1320
CYH A1309
HIS A1293
HIS A1311
 CUO  A9004 (-3.5A)
CUO  A9004 ( 3.9A)
CUO  A9004 (-3.2A)
CUO  A9004 (-3.4A)
 1.07A 5zrdB-4bedA:
2.7		 5zrdB-4bedA:
16.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZRD_B_CUB607_0
(TYROSINASE)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		4 / 5 HIS B1705
HIS B1725
HIS B1734
PHE B1874
 CUO  B9005 (-3.2A)
CUO  B9005 (-3.1A)
CUO  B9005 (-3.4A)
CUO  B9005 (-4.4A)
 0.31A 5zrdB-4bedB:
27.9		 5zrdB-4bedB:
15.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZRD_B_CUB607_0
(TYROSINASE)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		4 / 5 HIS B1847
HIS B1851
HIS B1878
PHE B1730
 CUO  B9005 (-3.2A)
CUO  B9005 (-3.2A)
CUO  B9005 (-3.3A)
CUO  B9005 ( 4.9A)
 1.22A 5zrdB-4bedB:
27.9		 5zrdB-4bedB:
15.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZRD_B_CUB607_0
(TYROSINASE)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		5 / 5 HIS B2122
CYH B2139
HIS B2141
HIS B2150
PHE B2287
 CUO  B9006 (-3.2A)
CUO  B9006 (-3.6A)
CUO  B9006 (-3.1A)
CUO  B9006 (-3.3A)
CUO  B9006 (-4.7A)
 1.02A 5zrdB-4bedB:
27.9		 5zrdB-4bedB:
15.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZRD_B_CUB607_0
(TYROSINASE)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		4 / 5 HIS B2141
CYH B2139
HIS B2150
HIS B2122
 CUO  B9006 (-3.1A)
CUO  B9006 (-3.6A)
CUO  B9006 (-3.3A)
CUO  B9006 (-3.2A)
 0.92A 5zrdB-4bedB:
27.9		 5zrdB-4bedB:
15.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZRD_B_CUB607_0
(TYROSINASE)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		4 / 5 HIS B2542
CYH B2559
HIS B2570
PHE B2697
 CUO  B9007 (-3.3A)
CUO  B9007 ( 3.7A)
CUO  B9007 (-3.3A)
CUO  B9007 (-4.7A)
 0.88A 5zrdB-4bedB:
27.9		 5zrdB-4bedB:
15.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZRD_B_CUB607_0
(TYROSINASE)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		4 / 5 HIS B2542
HIS B2561
HIS B2570
PHE B2697
 CUO  B9007 (-3.3A)
CUO  B9007 (-3.3A)
CUO  B9007 (-3.3A)
CUO  B9007 (-4.7A)
 0.39A 5zrdB-4bedB:
27.9		 5zrdB-4bedB:
15.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZRD_B_CUB607_0
(TYROSINASE)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		4 / 5 HIS B2570
CYH B2559
HIS B2542
HIS B2561
 CUO  B9007 (-3.3A)
CUO  B9007 ( 3.7A)
CUO  B9007 (-3.3A)
CUO  B9007 (-3.3A)
 1.05A 5zrdB-4bedB:
27.9		 5zrdB-4bedB:
15.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZRD_B_CUB607_0
(TYROSINASE)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		4 / 5 HIS B2670
HIS B2674
HIS B2701
PHE B2566
 CUO  B9007 (-3.4A)
CUO  B9007 (-3.4A)
CUO  B9007 (-3.1A)
CUO  B9007 ( 4.9A)
 1.11A 5zrdB-4bedB:
27.9		 5zrdB-4bedB:
15.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZRD_B_CUB607_0
(TYROSINASE)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		5 / 5 HIS B2946
CYH B2963
HIS B2965
HIS B2974
PHE B3102
 CUO  B9008 (-3.1A)
CUO  B9008 (-3.0A)
CUO  B9008 (-3.2A)
CUO  B9008 (-2.9A)
CUO  B9008 (-4.7A)
 0.73A 5zrdB-4bedB:
27.9		 5zrdB-4bedB:
15.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZRD_B_CUB607_0
(TYROSINASE)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		4 / 5 HIS B2965
HIS B2946
HIS B3106
PHE B2970
 CUO  B9008 (-3.2A)
CUO  B9008 (-3.1A)
CUO  B9008 (-3.3A)
None
 1.11A 5zrdB-4bedB:
27.9		 5zrdB-4bedB:
15.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZRD_B_CUB607_0
(TYROSINASE)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		4 / 5 HIS B3075
HIS B3079
HIS B3106
PHE B2970
 CUO  B9008 (-2.8A)
CUO  B9008 (-3.5A)
CUO  B9008 (-3.3A)
None
 1.14A 5zrdB-4bedB:
27.9		 5zrdB-4bedB:
15.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZRD_C_CUC604_0
(TYROSINASE)		 1js8 HEMOCYANIN
(Enteroctopus
dofleini) 		4 / 4 HIS A2671
HIS A2675
HIS A2701
HIS A2702
 CUO  A 888 (-3.4A)
CUO  A 888 (-3.3A)
None
CUO  A 888 (-3.3A)
 0.23A 5zrdC-1js8A:
27.2		 5zrdC-1js8A:
24.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZRD_C_CUC604_0
(TYROSINASE)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		4 / 4 HIS A 179
HIS A 183
HIS A 209
HIS A 210
 CUO  A9001 (-3.4A)
CUO  A9001 (-3.4A)
None
CUO  A9001 (-3.3A)
 0.77A 5zrdC-4bedA:
10.2		 5zrdC-4bedA:
16.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZRD_C_CUC604_0
(TYROSINASE)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		4 / 4 HIS A 210
HIS A  69
HIS A 179
HIS A 183
 CUO  A9001 (-3.3A)
CUO  A9001 (-3.1A)
CUO  A9001 (-3.4A)
CUO  A9001 (-3.4A)
 0.94A 5zrdC-4bedA:
10.2		 5zrdC-4bedA:
16.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZRD_C_CUC604_0
(TYROSINASE)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		4 / 4 HIS A 602
HIS A 606
HIS A 632
HIS A 633
 CUO  A9002 (-3.4A)
CUO  A9002 (-3.3A)
None
CUO  A9002 (-3.3A)
 0.88A 5zrdC-4bedA:
10.2		 5zrdC-4bedA:
16.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZRD_C_CUC604_0
(TYROSINASE)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		4 / 4 HIS A1015
HIS A1019
HIS A1045
HIS A1046
 CUO  A9003 (-3.1A)
CUO  A9003 (-3.4A)
None
CUO  A9003 (-3.2A)
 0.80A 5zrdC-4bedA:
10.2		 5zrdC-4bedA:
16.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZRD_C_CUC604_0
(TYROSINASE)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		4 / 4 HIS A1046
HIS A 905
HIS A1015
HIS A1019
 CUO  A9003 (-3.2A)
CUO  A9003 (-3.5A)
CUO  A9003 (-3.1A)
CUO  A9003 (-3.4A)
 0.97A 5zrdC-4bedA:
10.2		 5zrdC-4bedA:
16.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZRD_C_CUC604_0
(TYROSINASE)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		4 / 4 HIS A1424
HIS A1428
HIS A1454
HIS A1455
 CUO  A9004 (-3.0A)
CUO  A9004 (-3.4A)
None
CUO  A9004 (-3.3A)
 0.82A 5zrdC-4bedA:
10.2		 5zrdC-4bedA:
16.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZRD_C_CUC604_0
(TYROSINASE)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		4 / 4 HIS B1847
HIS B1851
HIS B1877
HIS B1878
 CUO  B9005 (-3.2A)
CUO  B9005 (-3.2A)
None
CUO  B9005 (-3.3A)
 0.82A 5zrdC-4bedB:
27.6		 5zrdC-4bedB:
15.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZRD_C_CUC604_0
(TYROSINASE)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		4 / 4 HIS B2260
HIS B2264
HIS B2290
HIS B2291
 CUO  B9006 (-3.2A)
CUO  B9006 (-3.2A)
None
CUO  B9006 (-3.5A)
 0.85A 5zrdC-4bedB:
27.6		 5zrdC-4bedB:
15.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZRD_C_CUC604_0
(TYROSINASE)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		4 / 4 HIS B2291
HIS B2150
HIS B2260
HIS B2264
 CUO  B9006 (-3.5A)
CUO  B9006 (-3.3A)
CUO  B9006 (-3.2A)
CUO  B9006 (-3.2A)
 0.86A 5zrdC-4bedB:
27.6		 5zrdC-4bedB:
15.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZRD_C_CUC604_0
(TYROSINASE)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		4 / 4 HIS B2670
HIS B2674
HIS B2700
HIS B2701
 CUO  B9007 (-3.4A)
CUO  B9007 (-3.4A)
None
CUO  B9007 (-3.1A)
 0.77A 5zrdC-4bedB:
27.6		 5zrdC-4bedB:
15.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZRD_C_CUC605_0
(TYROSINASE)		 1js8 HEMOCYANIN
(Enteroctopus
dofleini) 		5 / 5 HIS A2543
CYH A2560
HIS A2562
HIS A2571
PHE A2698
 CUO  A 888 (-3.4A)
CUO  A 888 ( 3.8A)
CUO  A 888 (-3.4A)
CUO  A 888 (-3.3A)
None
 0.43A 5zrdC-1js8A:
27.2		 5zrdC-1js8A:
24.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZRD_C_CUC605_0
(TYROSINASE)		 1js8 HEMOCYANIN
(Enteroctopus
dofleini) 		4 / 5 HIS A2671
HIS A2675
HIS A2702
PHE A2567
 CUO  A 888 (-3.4A)
CUO  A 888 (-3.3A)
CUO  A 888 (-3.3A)
CUO  A 888 (-4.8A)
 0.98A 5zrdC-1js8A:
27.2		 5zrdC-1js8A:
24.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZRD_C_CUC605_0
(TYROSINASE)		 3wky PROPHENOLOXIDASE B
(Marsupenaeus
japonicus) 		4 / 5 HIS A 199
HIS A 203
HIS A 226
PHE A 393
 CUO  A 708 (-3.3A)
CUO  A 708 (-3.5A)
CUO  A 708 (-3.3A)
CUO  A 708 (-4.5A)
 0.83A 5zrdC-3wkyA:
3.5		 5zrdC-3wkyA:
22.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZRD_C_CUC605_0
(TYROSINASE)		 3wky PROPHENOLOXIDASE B
(Marsupenaeus
japonicus) 		4 / 5 HIS A 203
HIS A 226
HIS A 199
PHE A  72
 CUO  A 708 (-3.5A)
CUO  A 708 (-3.3A)
CUO  A 708 (-3.3A)
CUO  A 708 (-4.6A)
 1.23A 5zrdC-3wkyA:
3.5		 5zrdC-3wkyA:
22.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZRD_C_CUC605_0
(TYROSINASE)		 3wky PROPHENOLOXIDASE B
(Marsupenaeus
japonicus) 		4 / 5 HIS A 357
HIS A 361
HIS A 397
PHE A 222
 CUO  A 708 (-3.3A)
CUO  A 708 (-3.2A)
CUO  A 708 (-3.4A)
None
 1.00A 5zrdC-3wkyA:
3.5		 5zrdC-3wkyA:
22.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZRD_C_CUC605_0
(TYROSINASE)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		5 / 5 HIS A  42
CYH A  58
HIS A  60
HIS A  69
PHE A 206
 CUO  A9001 (-3.4A)
CUO  A9001 ( 4.2A)
CUO  A9001 (-3.1A)
CUO  A9001 (-3.1A)
CUO  A9001 (-4.6A)
 0.58A 5zrdC-4bedA:
10.2		 5zrdC-4bedA:
16.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZRD_C_CUC605_0
(TYROSINASE)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		5 / 5 HIS A 462
CYH A 480
HIS A 482
HIS A 491
PHE A 629
 CUO  A9002 (-3.2A)
CUO  A9002 (-3.2A)
CUO  A9002 (-3.4A)
CUO  A9002 (-3.4A)
CUO  A9002 (-4.3A)
 0.90A 5zrdC-4bedA:
10.2		 5zrdC-4bedA:
16.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZRD_C_CUC605_0
(TYROSINASE)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		4 / 5 HIS A 482
CYH A 480
HIS A 491
HIS A 462
 CUO  A9002 (-3.4A)
CUO  A9002 (-3.2A)
CUO  A9002 (-3.4A)
CUO  A9002 (-3.2A)
 1.08A 5zrdC-4bedA:
10.2		 5zrdC-4bedA:
16.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZRD_C_CUC605_0
(TYROSINASE)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		4 / 5 HIS A 491
CYH A 480
HIS A 462
HIS A 482
 CUO  A9002 (-3.4A)
CUO  A9002 (-3.2A)
CUO  A9002 (-3.2A)
CUO  A9002 (-3.4A)
 1.23A 5zrdC-4bedA:
10.2		 5zrdC-4bedA:
16.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZRD_C_CUC605_0
(TYROSINASE)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		5 / 5 HIS A 876
CYH A 894
HIS A 896
HIS A 905
PHE A1042
 CUO  A9003 (-3.3A)
CUO  A9003 (-3.1A)
CUO  A9003 (-3.4A)
CUO  A9003 (-3.5A)
CUO  A9003 ( 4.9A)
 0.90A 5zrdC-4bedA:
10.2		 5zrdC-4bedA:
16.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZRD_C_CUC605_0
(TYROSINASE)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		4 / 5 HIS A 896
CYH A 894
HIS A 905
HIS A 876
 CUO  A9003 (-3.4A)
CUO  A9003 (-3.1A)
CUO  A9003 (-3.5A)
CUO  A9003 (-3.3A)
 1.06A 5zrdC-4bedA:
10.2		 5zrdC-4bedA:
16.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZRD_C_CUC605_0
(TYROSINASE)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		5 / 5 HIS A1293
CYH A1309
HIS A1311
HIS A1320
PHE A1451
 CUO  A9004 (-3.2A)
CUO  A9004 ( 3.9A)
CUO  A9004 (-3.4A)
CUO  A9004 (-3.5A)
CUO  A9004 (-4.5A)
 0.79A 5zrdC-4bedA:
10.2		 5zrdC-4bedA:
16.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZRD_C_CUC605_0
(TYROSINASE)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		4 / 5 HIS A1320
CYH A1309
HIS A1293
HIS A1311
 CUO  A9004 (-3.5A)
CUO  A9004 ( 3.9A)
CUO  A9004 (-3.2A)
CUO  A9004 (-3.4A)
 1.19A 5zrdC-4bedA:
10.2		 5zrdC-4bedA:
16.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZRD_C_CUC605_0
(TYROSINASE)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		4 / 5 HIS B1705
HIS B1725
HIS B1734
PHE B1874
 CUO  B9005 (-3.2A)
CUO  B9005 (-3.1A)
CUO  B9005 (-3.4A)
CUO  B9005 (-4.4A)
 0.36A 5zrdC-4bedB:
27.6		 5zrdC-4bedB:
15.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZRD_C_CUC605_0
(TYROSINASE)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		4 / 5 HIS B1847
HIS B1851
HIS B1878
PHE B1730
 CUO  B9005 (-3.2A)
CUO  B9005 (-3.2A)
CUO  B9005 (-3.3A)
CUO  B9005 ( 4.9A)
 1.25A 5zrdC-4bedB:
27.6		 5zrdC-4bedB:
15.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZRD_C_CUC605_0
(TYROSINASE)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		5 / 5 HIS B2122
CYH B2139
HIS B2141
HIS B2150
PHE B2287
 CUO  B9006 (-3.2A)
CUO  B9006 (-3.6A)
CUO  B9006 (-3.1A)
CUO  B9006 (-3.3A)
CUO  B9006 (-4.7A)
 1.06A 5zrdC-4bedB:
27.6		 5zrdC-4bedB:
15.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZRD_C_CUC605_0
(TYROSINASE)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		4 / 5 HIS B2141
CYH B2139
HIS B2150
HIS B2122
 CUO  B9006 (-3.1A)
CUO  B9006 (-3.6A)
CUO  B9006 (-3.3A)
CUO  B9006 (-3.2A)
 1.03A 5zrdC-4bedB:
27.6		 5zrdC-4bedB:
15.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZRD_C_CUC605_0
(TYROSINASE)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		4 / 5 HIS B2542
CYH B2559
HIS B2570
PHE B2697
 CUO  B9007 (-3.3A)
CUO  B9007 ( 3.7A)
CUO  B9007 (-3.3A)
CUO  B9007 (-4.7A)
 0.85A 5zrdC-4bedB:
27.6		 5zrdC-4bedB:
15.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZRD_C_CUC605_0
(TYROSINASE)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		4 / 5 HIS B2542
HIS B2561
HIS B2570
PHE B2697
 CUO  B9007 (-3.3A)
CUO  B9007 (-3.3A)
CUO  B9007 (-3.3A)
CUO  B9007 (-4.7A)
 0.42A 5zrdC-4bedB:
27.6		 5zrdC-4bedB:
15.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZRD_C_CUC605_0
(TYROSINASE)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		4 / 5 HIS B2570
CYH B2559
HIS B2542
HIS B2561
 CUO  B9007 (-3.3A)
CUO  B9007 ( 3.7A)
CUO  B9007 (-3.3A)
CUO  B9007 (-3.3A)
 1.16A 5zrdC-4bedB:
27.6		 5zrdC-4bedB:
15.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZRD_C_CUC605_0
(TYROSINASE)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		4 / 5 HIS B2670
HIS B2674
HIS B2701
PHE B2566
 CUO  B9007 (-3.4A)
CUO  B9007 (-3.4A)
CUO  B9007 (-3.1A)
CUO  B9007 ( 4.9A)
 1.15A 5zrdC-4bedB:
27.6		 5zrdC-4bedB:
15.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZRD_C_CUC605_0
(TYROSINASE)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		5 / 5 HIS B2946
CYH B2963
HIS B2965
HIS B2974
PHE B3102
 CUO  B9008 (-3.1A)
CUO  B9008 (-3.0A)
CUO  B9008 (-3.2A)
CUO  B9008 (-2.9A)
CUO  B9008 (-4.7A)
 0.78A 5zrdC-4bedB:
27.6		 5zrdC-4bedB:
15.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZRD_C_CUC605_0
(TYROSINASE)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		4 / 5 HIS B3075
HIS B3079
HIS B3106
PHE B2970
 CUO  B9008 (-2.8A)
CUO  B9008 (-3.5A)
CUO  B9008 (-3.3A)
None
 1.15A 5zrdC-4bedB:
27.6		 5zrdC-4bedB:
15.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZRD_D_CUD606_0
(TYROSINASE)		 1js8 HEMOCYANIN
(Enteroctopus
dofleini) 		5 / 5 HIS A2543
CYH A2560
HIS A2562
HIS A2571
PHE A2698
 CUO  A 888 (-3.4A)
CUO  A 888 ( 3.8A)
CUO  A 888 (-3.4A)
CUO  A 888 (-3.3A)
None
 0.45A 5zrdD-1js8A:
6.0		 5zrdD-1js8A:
24.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZRD_D_CUD606_0
(TYROSINASE)		 1js8 HEMOCYANIN
(Enteroctopus
dofleini) 		4 / 5 HIS A2671
HIS A2675
HIS A2702
PHE A2567
 CUO  A 888 (-3.4A)
CUO  A 888 (-3.3A)
CUO  A 888 (-3.3A)
CUO  A 888 (-4.8A)
 0.92A 5zrdD-1js8A:
6.0		 5zrdD-1js8A:
24.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZRD_D_CUD606_0
(TYROSINASE)		 3wky PROPHENOLOXIDASE B
(Marsupenaeus
japonicus) 		4 / 5 HIS A 199
HIS A 203
HIS A 226
PHE A 393
 CUO  A 708 (-3.3A)
CUO  A 708 (-3.5A)
CUO  A 708 (-3.3A)
CUO  A 708 (-4.5A)
 0.74A 5zrdD-3wkyA:
4.2		 5zrdD-3wkyA:
22.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZRD_D_CUD606_0
(TYROSINASE)		 3wky PROPHENOLOXIDASE B
(Marsupenaeus
japonicus) 		4 / 5 HIS A 357
HIS A 361
HIS A 397
PHE A 222
 CUO  A 708 (-3.3A)
CUO  A 708 (-3.2A)
CUO  A 708 (-3.4A)
None
 0.97A 5zrdD-3wkyA:
4.2		 5zrdD-3wkyA:
22.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZRD_D_CUD606_0
(TYROSINASE)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		5 / 5 HIS A  42
CYH A  58
HIS A  60
HIS A  69
PHE A 206
 CUO  A9001 (-3.4A)
CUO  A9001 ( 4.2A)
CUO  A9001 (-3.1A)
CUO  A9001 (-3.1A)
CUO  A9001 (-4.6A)
 0.51A 5zrdD-4bedA:
4.4		 5zrdD-4bedA:
16.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZRD_D_CUD606_0
(TYROSINASE)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		5 / 5 HIS A 462
CYH A 480
HIS A 482
HIS A 491
PHE A 629
 CUO  A9002 (-3.2A)
CUO  A9002 (-3.2A)
CUO  A9002 (-3.4A)
CUO  A9002 (-3.4A)
CUO  A9002 (-4.3A)
 0.87A 5zrdD-4bedA:
4.4		 5zrdD-4bedA:
16.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZRD_D_CUD606_0
(TYROSINASE)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		4 / 5 HIS A 482
CYH A 480
HIS A 491
HIS A 462
 CUO  A9002 (-3.4A)
CUO  A9002 (-3.2A)
CUO  A9002 (-3.4A)
CUO  A9002 (-3.2A)
 1.08A 5zrdD-4bedA:
4.4		 5zrdD-4bedA:
16.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZRD_D_CUD606_0
(TYROSINASE)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		4 / 5 HIS A 491
CYH A 480
HIS A 462
HIS A 482
 CUO  A9002 (-3.4A)
CUO  A9002 (-3.2A)
CUO  A9002 (-3.2A)
CUO  A9002 (-3.4A)
 1.17A 5zrdD-4bedA:
4.4		 5zrdD-4bedA:
16.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZRD_D_CUD606_0
(TYROSINASE)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		5 / 5 HIS A 876
CYH A 894
HIS A 896
HIS A 905
PHE A1042
 CUO  A9003 (-3.3A)
CUO  A9003 (-3.1A)
CUO  A9003 (-3.4A)
CUO  A9003 (-3.5A)
CUO  A9003 ( 4.9A)
 0.89A 5zrdD-4bedA:
4.4		 5zrdD-4bedA:
16.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZRD_D_CUD606_0
(TYROSINASE)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		4 / 5 HIS A 896
CYH A 894
HIS A 905
HIS A 876
 CUO  A9003 (-3.4A)
CUO  A9003 (-3.1A)
CUO  A9003 (-3.5A)
CUO  A9003 (-3.3A)
 1.06A 5zrdD-4bedA:
4.4		 5zrdD-4bedA:
16.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZRD_D_CUD606_0
(TYROSINASE)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		4 / 5 HIS A 905
CYH A 894
HIS A 876
HIS A 896
 CUO  A9003 (-3.5A)
CUO  A9003 (-3.1A)
CUO  A9003 (-3.3A)
CUO  A9003 (-3.4A)
 1.24A 5zrdD-4bedA:
4.4		 5zrdD-4bedA:
16.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZRD_D_CUD606_0
(TYROSINASE)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		5 / 5 HIS A1293
CYH A1309
HIS A1311
HIS A1320
PHE A1451
 CUO  A9004 (-3.2A)
CUO  A9004 ( 3.9A)
CUO  A9004 (-3.4A)
CUO  A9004 (-3.5A)
CUO  A9004 (-4.5A)
 0.82A 5zrdD-4bedA:
4.4		 5zrdD-4bedA:
16.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZRD_D_CUD606_0
(TYROSINASE)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		4 / 5 HIS A1320
CYH A1309
HIS A1293
HIS A1311
 CUO  A9004 (-3.5A)
CUO  A9004 ( 3.9A)
CUO  A9004 (-3.2A)
CUO  A9004 (-3.4A)
 1.09A 5zrdD-4bedA:
4.4		 5zrdD-4bedA:
16.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZRD_D_CUD606_0
(TYROSINASE)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		4 / 5 HIS A1424
HIS A1428
HIS A1455
PHE A1316
 CUO  A9004 (-3.0A)
CUO  A9004 (-3.4A)
CUO  A9004 (-3.3A)
None
 1.25A 5zrdD-4bedA:
4.4		 5zrdD-4bedA:
16.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZRD_D_CUD606_0
(TYROSINASE)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		4 / 5 HIS B1705
HIS B1725
HIS B1734
PHE B1874
 CUO  B9005 (-3.2A)
CUO  B9005 (-3.1A)
CUO  B9005 (-3.4A)
CUO  B9005 (-4.4A)
 0.30A 5zrdD-4bedB:
27.7		 5zrdD-4bedB:
15.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZRD_D_CUD606_0
(TYROSINASE)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		4 / 5 HIS B1847
HIS B1851
HIS B1878
PHE B1730
 CUO  B9005 (-3.2A)
CUO  B9005 (-3.2A)
CUO  B9005 (-3.3A)
CUO  B9005 ( 4.9A)
 1.20A 5zrdD-4bedB:
27.7		 5zrdD-4bedB:
15.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZRD_D_CUD606_0
(TYROSINASE)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		5 / 5 HIS B2122
CYH B2139
HIS B2141
HIS B2150
PHE B2287
 CUO  B9006 (-3.2A)
CUO  B9006 (-3.6A)
CUO  B9006 (-3.1A)
CUO  B9006 (-3.3A)
CUO  B9006 (-4.7A)
 1.05A 5zrdD-4bedB:
27.7		 5zrdD-4bedB:
15.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZRD_D_CUD606_0
(TYROSINASE)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		4 / 5 HIS B2141
CYH B2139
HIS B2150
HIS B2122
 CUO  B9006 (-3.1A)
CUO  B9006 (-3.6A)
CUO  B9006 (-3.3A)
CUO  B9006 (-3.2A)
 0.99A 5zrdD-4bedB:
27.7		 5zrdD-4bedB:
15.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZRD_D_CUD606_0
(TYROSINASE)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		5 / 5 HIS B2542
CYH B2559
HIS B2561
HIS B2570
PHE B2697
 CUO  B9007 (-3.3A)
CUO  B9007 ( 3.7A)
CUO  B9007 (-3.3A)
CUO  B9007 (-3.3A)
CUO  B9007 (-4.7A)
 0.88A 5zrdD-4bedB:
27.7		 5zrdD-4bedB:
15.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZRD_D_CUD606_0
(TYROSINASE)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		4 / 5 HIS B2570
CYH B2559
HIS B2542
HIS B2561
 CUO  B9007 (-3.3A)
CUO  B9007 ( 3.7A)
CUO  B9007 (-3.3A)
CUO  B9007 (-3.3A)
 1.07A 5zrdD-4bedB:
27.7		 5zrdD-4bedB:
15.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZRD_D_CUD606_0
(TYROSINASE)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		4 / 5 HIS B2670
HIS B2674
HIS B2701
PHE B2566
 CUO  B9007 (-3.4A)
CUO  B9007 (-3.4A)
CUO  B9007 (-3.1A)
CUO  B9007 ( 4.9A)
 1.09A 5zrdD-4bedB:
27.7		 5zrdD-4bedB:
15.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZRD_D_CUD606_0
(TYROSINASE)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		5 / 5 HIS B2946
CYH B2963
HIS B2965
HIS B2974
PHE B3102
 CUO  B9008 (-3.1A)
CUO  B9008 (-3.0A)
CUO  B9008 (-3.2A)
CUO  B9008 (-2.9A)
CUO  B9008 (-4.7A)
 0.66A 5zrdD-4bedB:
27.7		 5zrdD-4bedB:
15.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZRD_D_CUD606_0
(TYROSINASE)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		4 / 5 HIS B3075
HIS B3079
HIS B3106
PHE B2970
 CUO  B9008 (-2.8A)
CUO  B9008 (-3.5A)
CUO  B9008 (-3.3A)
None
 1.12A 5zrdD-4bedB:
27.7		 5zrdD-4bedB:
15.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZRD_D_CUD607_0
(TYROSINASE)		 1js8 HEMOCYANIN
(Enteroctopus
dofleini) 		4 / 4 HIS A2671
HIS A2675
HIS A2701
HIS A2702
 CUO  A 888 (-3.4A)
CUO  A 888 (-3.3A)
None
CUO  A 888 (-3.3A)
 0.26A 5zrdD-1js8A:
6.0		 5zrdD-1js8A:
24.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZRD_D_CUD607_0
(TYROSINASE)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		4 / 4 HIS A 179
HIS A 183
HIS A 209
HIS A 210
 CUO  A9001 (-3.4A)
CUO  A9001 (-3.4A)
None
CUO  A9001 (-3.3A)
 0.72A 5zrdD-4bedA:
4.4		 5zrdD-4bedA:
16.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZRD_D_CUD607_0
(TYROSINASE)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		4 / 4 HIS A 602
HIS A 606
HIS A 632
HIS A 633
 CUO  A9002 (-3.4A)
CUO  A9002 (-3.3A)
None
CUO  A9002 (-3.3A)
 0.85A 5zrdD-4bedA:
4.4		 5zrdD-4bedA:
16.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZRD_D_CUD607_0
(TYROSINASE)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		4 / 4 HIS A1015
HIS A1019
HIS A1045
HIS A1046
 CUO  A9003 (-3.1A)
CUO  A9003 (-3.4A)
None
CUO  A9003 (-3.2A)
 0.76A 5zrdD-4bedA:
4.4		 5zrdD-4bedA:
16.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZRD_D_CUD607_0
(TYROSINASE)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		4 / 4 HIS A1424
HIS A1428
HIS A1454
HIS A1455
 CUO  A9004 (-3.0A)
CUO  A9004 (-3.4A)
None
CUO  A9004 (-3.3A)
 0.77A 5zrdD-4bedA:
4.4		 5zrdD-4bedA:
16.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZRD_D_CUD607_0
(TYROSINASE)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		4 / 4 HIS B1847
HIS B1851
HIS B1877
HIS B1878
 CUO  B9005 (-3.2A)
CUO  B9005 (-3.2A)
None
CUO  B9005 (-3.3A)
 0.78A 5zrdD-4bedB:
27.6		 5zrdD-4bedB:
15.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZRD_D_CUD607_0
(TYROSINASE)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		4 / 4 HIS B2260
HIS B2264
HIS B2290
HIS B2291
 CUO  B9006 (-3.2A)
CUO  B9006 (-3.2A)
None
CUO  B9006 (-3.5A)
 0.81A 5zrdD-4bedB:
27.6		 5zrdD-4bedB:
15.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZRD_D_CUD607_0
(TYROSINASE)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		4 / 4 HIS B2291
HIS B2150
HIS B2260
HIS B2264
 CUO  B9006 (-3.5A)
CUO  B9006 (-3.3A)
CUO  B9006 (-3.2A)
CUO  B9006 (-3.2A)
 0.86A 5zrdD-4bedB:
27.6		 5zrdD-4bedB:
15.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZRD_D_CUD607_0
(TYROSINASE)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		4 / 4 HIS B2670
HIS B2674
HIS B2700
HIS B2701
 CUO  B9007 (-3.4A)
CUO  B9007 (-3.4A)
None
CUO  B9007 (-3.1A)
 0.74A 5zrdD-4bedB:
27.6		 5zrdD-4bedB:
15.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6C2M_D_SUED1202_1
(NS3 PROTEASE)		 1js8 HEMOCYANIN
(Enteroctopus
dofleini) 		4 / 9 HIS A2571
VAL A2583
SER A2587
ASP A2580
 CUO  A 888 (-3.3A)
None
None
None
 0.98A 6c2mD-1js8A:
undetectable		 6c2mD-1js8A:
13.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6ESM_A_PZEA307_1
(MATRIX
METALLOPROTEINASE-9,
MATRIX
METALLOPROTEINASE-9)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		3 / 3 TYR B2153
HIS B2150
PHE B2287
 None
CUO  B9006 (-3.3A)
CUO  B9006 (-4.7A)
 1.06A 6esmA-4bedB:
undetectable		 6esmA-4bedB:
4.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GIQ_A_CUA601_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1js8 HEMOCYANIN
(Enteroctopus
dofleini) 		3 / 3 HIS A2671
HIS A2702
HIS A2701
 CUO  A 888 (-3.4A)
CUO  A 888 (-3.3A)
None
 0.72A 6giqa-1js8A:
undetectable		 6giqa-1js8A:
21.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GIQ_A_CUA601_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		3 / 3 HIS A 633
HIS A 606
HIS A 602
 CUO  A9002 (-3.3A)
CUO  A9002 (-3.3A)
CUO  A9002 (-3.4A)
 0.73A 6giqa-4bedA:
undetectable		 6giqa-4bedA:
16.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GIQ_A_CUA601_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		3 / 3 HIS B1878
HIS B1851
HIS B1847
 CUO  B9005 (-3.3A)
CUO  B9005 (-3.2A)
CUO  B9005 (-3.2A)
 0.66A 6giqa-4bedB:
undetectable		 6giqa-4bedB:
14.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GIQ_A_CUA601_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		3 / 3 HIS B2701
HIS B2674
HIS B2670
 CUO  B9007 (-3.1A)
CUO  B9007 (-3.4A)
CUO  B9007 (-3.4A)
 0.62A 6giqa-4bedB:
undetectable		 6giqa-4bedB:
14.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GIQ_A_CUA601_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		3 / 3 HIS B3106
HIS B3079
HIS B3075
 CUO  B9008 (-3.3A)
CUO  B9008 (-3.5A)
CUO  B9008 (-2.8A)
 0.70A 6giqa-4bedB:
undetectable		 6giqa-4bedB:
14.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HU9_A_CUA601_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1js8 HEMOCYANIN
(Enteroctopus
dofleini) 		3 / 3 HIS A2671
HIS A2702
HIS A2701
 CUO  A 888 (-3.4A)
CUO  A 888 (-3.3A)
None
 0.67A 6hu9a-1js8A:
undetectable		 6hu9a-1js8A:
21.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HU9_M_CUM601_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1js8 HEMOCYANIN
(Enteroctopus
dofleini) 		3 / 3 HIS A2671
HIS A2702
HIS A2701
 CUO  A 888 (-3.4A)
CUO  A 888 (-3.3A)
None
 0.74A 6hu9m-1js8A:
undetectable		 6hu9m-1js8A:
21.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NMF_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1js8 HEMOCYANIN
(Enteroctopus
dofleini) 		3 / 3 HIS A2671
HIS A2702
HIS A2701
 CUO  A 888 (-3.4A)
CUO  A 888 (-3.3A)
None
 0.71A 6nmfA-1js8A:
1.1		 6nmfA-1js8A:
21.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NMF_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		3 / 3 HIS B2946
HIS B3106
HIS B2974
 CUO  B9008 (-3.1A)
CUO  B9008 (-3.3A)
CUO  B9008 (-2.9A)
 0.72A 6nmfA-4bedB:
0.7		 6nmfA-4bedB:
14.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NMF_N_CUN603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1js8 HEMOCYANIN
(Enteroctopus
dofleini) 		3 / 3 HIS A2671
HIS A2702
HIS A2701
 CUO  A 888 (-3.4A)
CUO  A 888 (-3.3A)
None
 0.71A 6nmfN-1js8A:
undetectable		 6nmfN-1js8A:
21.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NMF_N_CUN603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		3 / 3 HIS B2946
HIS B3106
HIS B2974
 CUO  B9008 (-3.1A)
CUO  B9008 (-3.3A)
CUO  B9008 (-2.9A)
 0.69A 6nmfN-4bedB:
undetectable		 6nmfN-4bedB:
14.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NMP_A_CUA601_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 4bed HEMOCYANIN KLH1
(Megathura
crenulata) 		3 / 3 HIS B2946
HIS B3106
HIS B2974
 CUO  B9008 (-3.1A)
CUO  B9008 (-3.3A)
CUO  B9008 (-2.9A)
 0.76A 6nmpA-4bedB:
undetectable		 6nmpA-4bedB:
14.43