SIMILAR PATTERN OF AMINO ACIDS MAPPED TO 'MLT'


List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1AM6_A_HAEA555_1
(CARBONIC ANHYDRASE)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		7 / 7 HIS A 123
HIS A 125
HIS A 142
LEU A 214
THR A 215
THR A 216
TRP A 225
 ZN  A   1 ( 3.2A)
ZN  A   1 (-3.3A)
ZN  A   1 ( 3.2A)
MLT  A   3 ( 4.2A)
MLT  A   3 ( 4.3A)
MLT  A   3 (-2.8A)
MLT  A   3 (-4.9A)
 0.35A 1am6A-3q31A:
24.3		 1am6A-3q31A:
30.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AZM_A_AZMA262_1
(CARBONIC ANHYDRASE I)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		6 / 8 HIS A 123
HIS A 125
HIS A 142
LEU A 214
THR A 215
TRP A 225
 ZN  A   1 ( 3.2A)
ZN  A   1 (-3.3A)
ZN  A   1 ( 3.2A)
MLT  A   3 ( 4.2A)
MLT  A   3 ( 4.3A)
MLT  A   3 (-4.9A)
 0.35A 1azmA-3q31A:
23.5		 1azmA-3q31A:
28.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1B2I_A_AMHA84_1
(PROTEIN
(PLASMINOGEN))		 5u8q FV 24-60 HEAVY CHAIN
INSULIN-LIKE GROWTH
FACTOR 1 RECEPTOR
(Homo
sapiens;
Mus
musculus) 		4 / 7 TYR H  54
GLU A  53
PHE A 241
ARG A 245
 None
None
None
MLT  A1003 ( 4.8A)
 1.47A 1b2iA-5u8qH:
undetectable		 1b2iA-5u8qH:
25.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1BZM_A_MZMA262_1
(CARBONIC ANHYDRASE I)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		6 / 8 HIS A 123
HIS A 125
HIS A 142
LEU A 214
THR A 215
TRP A 225
 ZN  A   1 ( 3.2A)
ZN  A   1 (-3.3A)
ZN  A   1 ( 3.2A)
MLT  A   3 ( 4.2A)
MLT  A   3 ( 4.3A)
MLT  A   3 (-4.9A)
 0.32A 1bzmA-3q31A:
23.4		 1bzmA-3q31A:
28.77
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1CIL_A_ETSA263_1
(CARBONIC ANHYDRASE
II)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		6 / 12 GLN A 102
HIS A 123
HIS A 125
HIS A 142
THR A 215
THR A 216
 None
ZN  A   1 ( 3.2A)
ZN  A   1 (-3.3A)
ZN  A   1 ( 3.2A)
MLT  A   3 ( 4.3A)
MLT  A   3 (-2.8A)
 1.06A 1cilA-3q31A:
24.3		 1cilA-3q31A:
30.69
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1CIL_A_ETSA263_1
(CARBONIC ANHYDRASE
II)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		5 / 12 GLN A 102
HIS A 125
VAL A 144
THR A 215
THR A 216
 None
ZN  A   1 (-3.3A)
None
MLT  A   3 ( 4.3A)
MLT  A   3 (-2.8A)
 1.11A 1cilA-3q31A:
24.3		 1cilA-3q31A:
30.69
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1CIL_A_ETSA263_1
(CARBONIC ANHYDRASE
II)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		10 / 12 GLN A 121
HIS A 123
HIS A 125
HIS A 142
VAL A 144
VAL A 154
LEU A 214
THR A 215
THR A 216
TRP A 225
 MLT  A   3 (-3.9A)
ZN  A   1 ( 3.2A)
ZN  A   1 (-3.3A)
ZN  A   1 ( 3.2A)
None
MLT  A   3 (-4.6A)
MLT  A   3 ( 4.2A)
MLT  A   3 ( 4.3A)
MLT  A   3 (-2.8A)
MLT  A   3 (-4.9A)
 0.40A 1cilA-3q31A:
24.3		 1cilA-3q31A:
30.69
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1CIL_A_ETSA263_1
(CARBONIC ANHYDRASE
II)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		6 / 12 GLN A 121
HIS A 123
HIS A 125
VAL A 144
LEU A 214
THR A 215
 MLT  A   3 (-3.9A)
ZN  A   1 ( 3.2A)
ZN  A   1 (-3.3A)
None
MLT  A   3 ( 4.2A)
MLT  A   3 ( 4.3A)
 1.41A 1cilA-3q31A:
24.3		 1cilA-3q31A:
30.69
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1CIL_A_ETSA263_1
(CARBONIC ANHYDRASE
II)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		6 / 12 HIS A 123
HIS A 142
VAL A 154
LEU A 214
THR A 216
TRP A 225
 ZN  A   1 ( 3.2A)
ZN  A   1 ( 3.2A)
MLT  A   3 (-4.6A)
MLT  A   3 ( 4.2A)
MLT  A   3 (-2.8A)
MLT  A   3 (-4.9A)
 1.46A 1cilA-3q31A:
24.3		 1cilA-3q31A:
30.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DMY_A_AZMA400_1
(MURINE CARBONIC
ANHYDRASE V)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		8 / 11 HIS A 123
HIS A 125
HIS A 142
VAL A 144
LEU A 214
THR A 215
THR A 216
TRP A 225
 ZN  A   1 ( 3.2A)
ZN  A   1 (-3.3A)
ZN  A   1 ( 3.2A)
None
MLT  A   3 ( 4.2A)
MLT  A   3 ( 4.3A)
MLT  A   3 (-2.8A)
MLT  A   3 (-4.9A)
 0.37A 1dmyA-3q31A:
21.0		 1dmyA-3q31A:
28.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DMY_A_AZMA400_1
(MURINE CARBONIC
ANHYDRASE V)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		6 / 11 HIS A 123
HIS A 142
LEU A 214
THR A 215
THR A 216
TRP A 225
 ZN  A   1 ( 3.2A)
ZN  A   1 ( 3.2A)
MLT  A   3 ( 4.2A)
MLT  A   3 ( 4.3A)
MLT  A   3 (-2.8A)
MLT  A   3 (-4.9A)
 1.49A 1dmyA-3q31A:
21.0		 1dmyA-3q31A:
28.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DMY_A_AZMA400_1
(MURINE CARBONIC
ANHYDRASE V)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		5 / 11 HIS A 142
HIS A 123
HIS A 125
TYR A 210
THR A 216
 ZN  A   1 ( 3.2A)
ZN  A   1 ( 3.2A)
ZN  A   1 (-3.3A)
None
MLT  A   3 (-2.8A)
 1.09A 1dmyA-3q31A:
21.0		 1dmyA-3q31A:
28.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DMY_A_AZMA400_1
(MURINE CARBONIC
ANHYDRASE V)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		5 / 11 HIS A 142
HIS A 125
VAL A 154
LEU A 214
THR A 216
 ZN  A   1 ( 3.2A)
ZN  A   1 (-3.3A)
MLT  A   3 (-4.6A)
MLT  A   3 ( 4.2A)
MLT  A   3 (-2.8A)
 1.35A 1dmyA-3q31A:
21.0		 1dmyA-3q31A:
28.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DMY_B_AZMB900_1
(MURINE CARBONIC
ANHYDRASE V)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		7 / 12 GLN A 102
HIS A 123
HIS A 125
HIS A 142
LEU A 214
THR A 215
THR A 216
 None
ZN  A   1 ( 3.2A)
ZN  A   1 (-3.3A)
ZN  A   1 ( 3.2A)
MLT  A   3 ( 4.2A)
MLT  A   3 ( 4.3A)
MLT  A   3 (-2.8A)
 1.10A 1dmyB-3q31A:
21.1		 1dmyB-3q31A:
28.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DMY_B_AZMB900_1
(MURINE CARBONIC
ANHYDRASE V)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		7 / 12 GLN A 102
HIS A 123
HIS A 125
VAL A 144
LEU A 214
THR A 215
THR A 216
 None
ZN  A   1 ( 3.2A)
ZN  A   1 (-3.3A)
None
MLT  A   3 ( 4.2A)
MLT  A   3 ( 4.3A)
MLT  A   3 (-2.8A)
 1.31A 1dmyB-3q31A:
21.1		 1dmyB-3q31A:
28.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DMY_B_AZMB900_1
(MURINE CARBONIC
ANHYDRASE V)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		10 / 12 GLN A 121
HIS A 123
HIS A 125
HIS A 142
VAL A 144
VAL A 154
LEU A 214
THR A 215
THR A 216
TRP A 225
 MLT  A   3 (-3.9A)
ZN  A   1 ( 3.2A)
ZN  A   1 (-3.3A)
ZN  A   1 ( 3.2A)
None
MLT  A   3 (-4.6A)
MLT  A   3 ( 4.2A)
MLT  A   3 ( 4.3A)
MLT  A   3 (-2.8A)
MLT  A   3 (-4.9A)
 0.42A 1dmyB-3q31A:
21.1		 1dmyB-3q31A:
28.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DMY_B_AZMB900_1
(MURINE CARBONIC
ANHYDRASE V)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		7 / 12 HIS A 123
HIS A 142
VAL A 154
LEU A 214
THR A 215
THR A 216
TRP A 225
 ZN  A   1 ( 3.2A)
ZN  A   1 ( 3.2A)
MLT  A   3 (-4.6A)
MLT  A   3 ( 4.2A)
MLT  A   3 ( 4.3A)
MLT  A   3 (-2.8A)
MLT  A   3 (-4.9A)
 1.46A 1dmyB-3q31A:
21.1		 1dmyB-3q31A:
28.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DMY_B_AZMB900_1
(MURINE CARBONIC
ANHYDRASE V)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		5 / 12 HIS A 142
HIS A 123
HIS A 125
TYR A 210
THR A 216
 ZN  A   1 ( 3.2A)
ZN  A   1 ( 3.2A)
ZN  A   1 (-3.3A)
None
MLT  A   3 (-2.8A)
 1.08A 1dmyB-3q31A:
21.1		 1dmyB-3q31A:
28.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EI6_A_PPFA410_1
(PHOSPHONOACETATE
HYDROLASE)		 3g1p PROTEIN PHNP
(Escherichia
coli) 		4 / 5 ASP A 164
HIS A 143
HIS A 222
HIS A 200
 MN  A 401 (-2.1A)
MN  A 400 ( 3.4A)
MN  A 401 (-3.7A)
MLT  A 500 (-4.1A)
 1.18A 1ei6A-3g1pA:
undetectable		 1ei6A-3g1pA:
21.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EIZ_A_SAMA301_0
(FTSJ)		 5ikm NS5 METHYL
TRANSFERASE
(Dengue
virus) 		6 / 12 GLY A  81
GLY A  85
GLY A  86
TRP A  87
ARG A 163
LYS A 180
 SAM  A 311 (-3.2A)
SAM  A 311 ( 4.5A)
SAM  A 311 (-3.3A)
SAM  A 311 (-3.5A)
MLT  A 313 (-2.8A)
None
 1.31A 1eizA-5ikmA:
13.7		 1eizA-5ikmA:
26.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FFY_A_MRCA1993_1
(ISOLEUCYL-TRNA
SYNTHETASE)		 3uk2 PANTOTHENATE
SYNTHETASE
(Burkholderia
thailandensis) 		5 / 12 HIS A  30
GLY A  32
GLY A 144
ASP A 147
VAL A 173
 AMP  A 280 (-4.7A)
AMP  A 280 ( 3.9A)
AMP  A 280 (-3.3A)
MLT  A 284 ( 3.5A)
AMP  A 280 (-3.9A)
 0.93A 1ffyA-3uk2A:
2.5		 1ffyA-3uk2A:
14.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FXH_B_PACB1001_0
(PENICILLIN ACYLASE)		 4pfr TRAP DICARBOXYLATE
TRANSPORTER, DCTP
SUBUNIT
(Rhodobacter
sphaeroides) 		4 / 7 MET A 229
SER A 168
ALA A 173
ILE A 172
 None
MLT  A 401 ( 4.5A)
None
None
 0.92A 1fxhA-4pfrA:
undetectable
1fxhB-4pfrA:
1.0		 1fxhA-4pfrA:
23.32
1fxhB-4pfrA:
21.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HWI_C_115C4_2
(HMG-COA REDUCTASE)		 3og9 PROTEIN YAHD A
COPPER INDUCIBLE
HYDROLASE
(Lactococcus
lactis) 		4 / 8 ASN A 108
LEU A  19
ALA A 103
LEU A  17
 MLT  A 500 (-3.9A)
None
None
None
 0.94A 1hwiD-3og9A:
undetectable		 1hwiD-3og9A:
16.70
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1J36_A_LPRA801_1
(ANGIOTENSIN
CONVERTING ENZYME)		 5a2r ANGIOTENSIN-CONVERTI
NG ENZYME
(Drosophila
melanogaster) 		12 / 12 GLN A 265
HIS A 337
THR A 364
HIS A 367
GLU A 368
HIS A 371
GLU A 395
LYS A 495
HIS A 497
VAL A 502
TYR A 504
TYR A 507
 MLT  A1615 (-3.2A)
MLT  A1615 (-3.8A)
None
ZN  A1616 (-3.2A)
MLT  A1615 (-4.3A)
ZN  A1616 (-3.3A)
ZN  A1616 (-2.4A)
MLT  A1615 (-2.7A)
MLT  A1615 (-4.0A)
None
MLT  A1615 (-4.7A)
MLT  A1615 (-4.0A)
 0.30A 1j36A-5a2rA:
58.8		 1j36A-5a2rA:
99.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1J36_B_LPRB802_1
(ANGIOTENSIN
CONVERTING ENZYME)		 5a2r ANGIOTENSIN-CONVERTI
NG ENZYME
(Drosophila
melanogaster) 		12 / 12 GLN A 265
HIS A 337
THR A 364
HIS A 367
GLU A 368
HIS A 371
GLU A 395
LYS A 495
HIS A 497
VAL A 502
TYR A 504
TYR A 507
 MLT  A1615 (-3.2A)
MLT  A1615 (-3.8A)
None
ZN  A1616 (-3.2A)
MLT  A1615 (-4.3A)
ZN  A1616 (-3.3A)
ZN  A1616 (-2.4A)
MLT  A1615 (-2.7A)
MLT  A1615 (-4.0A)
None
MLT  A1615 (-4.7A)
MLT  A1615 (-4.0A)
 0.30A 1j36B-5a2rA:
38.7		 1j36B-5a2rA:
99.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1J37_A_X8ZA801_1
(ANGIOTENSIN
CONVERTING ENZYME)		 5a2r ANGIOTENSIN-CONVERTI
NG ENZYME
(Drosophila
melanogaster) 		11 / 11 GLN A 265
HIS A 337
HIS A 367
GLU A 368
HIS A 371
GLU A 395
PHE A 441
LYS A 495
HIS A 497
TYR A 504
TYR A 507
 MLT  A1615 (-3.2A)
MLT  A1615 (-3.8A)
ZN  A1616 (-3.2A)
MLT  A1615 (-4.3A)
ZN  A1616 (-3.3A)
ZN  A1616 (-2.4A)
MLT  A1615 ( 4.8A)
MLT  A1615 (-2.7A)
MLT  A1615 (-4.0A)
MLT  A1615 (-4.7A)
MLT  A1615 (-4.0A)
 0.30A 1j37A-5a2rA:
58.0		 1j37A-5a2rA:
99.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1J37_A_X8ZA801_1
(ANGIOTENSIN
CONVERTING ENZYME)		 5a2r ANGIOTENSIN-CONVERTI
NG ENZYME
(Drosophila
melanogaster) 		5 / 11 HIS A 367
GLU A 368
HIS A 371
GLU A 395
PHE A 511
 ZN  A1616 (-3.2A)
MLT  A1615 (-4.3A)
ZN  A1616 (-3.3A)
ZN  A1616 (-2.4A)
None
 1.10A 1j37A-5a2rA:
58.0		 1j37A-5a2rA:
99.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1J37_B_X8ZB802_1
(ANGIOTENSIN
CONVERTING ENZYME)		 5a2r ANGIOTENSIN-CONVERTI
NG ENZYME
(Drosophila
melanogaster) 		11 / 11 GLN A 265
HIS A 337
HIS A 367
GLU A 368
HIS A 371
GLU A 395
PHE A 441
LYS A 495
HIS A 497
TYR A 504
TYR A 507
 MLT  A1615 (-3.2A)
MLT  A1615 (-3.8A)
ZN  A1616 (-3.2A)
MLT  A1615 (-4.3A)
ZN  A1616 (-3.3A)
ZN  A1616 (-2.4A)
MLT  A1615 ( 4.8A)
MLT  A1615 (-2.7A)
MLT  A1615 (-4.0A)
MLT  A1615 (-4.7A)
MLT  A1615 (-4.0A)
 0.31A 1j37B-5a2rA:
58.0		 1j37B-5a2rA:
99.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1J37_B_X8ZB802_1
(ANGIOTENSIN
CONVERTING ENZYME)		 5a2r ANGIOTENSIN-CONVERTI
NG ENZYME
(Drosophila
melanogaster) 		5 / 11 HIS A 367
GLU A 368
HIS A 371
GLU A 395
PHE A 511
 ZN  A1616 (-3.2A)
MLT  A1615 (-4.3A)
ZN  A1616 (-3.3A)
ZN  A1616 (-2.4A)
None
 1.10A 1j37B-5a2rA:
58.0		 1j37B-5a2rA:
99.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JD0_A_AZMA1400_1
(CARBONIC ANHYDRASE
XII)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		6 / 9 GLN A 102
HIS A 123
HIS A 125
HIS A 142
THR A 215
THR A 216
 None
ZN  A   1 ( 3.2A)
ZN  A   1 (-3.3A)
ZN  A   1 ( 3.2A)
MLT  A   3 ( 4.3A)
MLT  A   3 (-2.8A)
 0.91A 1jd0A-3q31A:
24.7		 1jd0A-3q31A:
26.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JD0_A_AZMA1400_1
(CARBONIC ANHYDRASE
XII)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		9 / 9 GLN A 121
HIS A 123
HIS A 125
HIS A 142
VAL A 144
LEU A 214
THR A 215
THR A 216
TRP A 225
 MLT  A   3 (-3.9A)
ZN  A   1 ( 3.2A)
ZN  A   1 (-3.3A)
ZN  A   1 ( 3.2A)
None
MLT  A   3 ( 4.2A)
MLT  A   3 ( 4.3A)
MLT  A   3 (-2.8A)
MLT  A   3 (-4.9A)
 0.50A 1jd0A-3q31A:
24.7		 1jd0A-3q31A:
26.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JD0_A_AZMA1400_1
(CARBONIC ANHYDRASE
XII)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		6 / 9 GLN A 121
HIS A 123
HIS A 125
VAL A 144
LEU A 214
THR A 215
 MLT  A   3 (-3.9A)
ZN  A   1 ( 3.2A)
ZN  A   1 (-3.3A)
None
MLT  A   3 ( 4.2A)
MLT  A   3 ( 4.3A)
 1.49A 1jd0A-3q31A:
24.7		 1jd0A-3q31A:
26.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JD0_A_AZMA1400_1
(CARBONIC ANHYDRASE
XII)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		6 / 9 HIS A 123
HIS A 142
LEU A 214
THR A 215
THR A 216
TRP A 225
 ZN  A   1 ( 3.2A)
ZN  A   1 ( 3.2A)
MLT  A   3 ( 4.2A)
MLT  A   3 ( 4.3A)
MLT  A   3 (-2.8A)
MLT  A   3 (-4.9A)
 1.42A 1jd0A-3q31A:
24.7		 1jd0A-3q31A:
26.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JD0_A_AZMA1400_1
(CARBONIC ANHYDRASE
XII)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		5 / 9 HIS A 125
VAL A 154
LEU A 214
THR A 215
THR A 216
 ZN  A   1 (-3.3A)
MLT  A   3 (-4.6A)
MLT  A   3 ( 4.2A)
MLT  A   3 ( 4.3A)
MLT  A   3 (-2.8A)
 0.88A 1jd0A-3q31A:
24.7		 1jd0A-3q31A:
26.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JD0_A_AZMA1400_1
(CARBONIC ANHYDRASE
XII)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		5 / 9 HIS A 142
HIS A 125
VAL A 154
LEU A 214
THR A 216
 ZN  A   1 ( 3.2A)
ZN  A   1 (-3.3A)
MLT  A   3 (-4.6A)
MLT  A   3 ( 4.2A)
MLT  A   3 (-2.8A)
 1.32A 1jd0A-3q31A:
24.7		 1jd0A-3q31A:
26.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JD0_B_AZMB2401_1
(CARBONIC ANHYDRASE
XII)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		7 / 11 GLN A 102
HIS A 123
HIS A 125
GLU A 129
HIS A 142
THR A 215
THR A 216
 None
ZN  A   1 ( 3.2A)
ZN  A   1 (-3.3A)
ZN  A   1 ( 4.7A)
ZN  A   1 ( 3.2A)
MLT  A   3 ( 4.3A)
MLT  A   3 (-2.8A)
 0.91A 1jd0B-3q31A:
24.6		 1jd0B-3q31A:
26.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JD0_B_AZMB2401_1
(CARBONIC ANHYDRASE
XII)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		6 / 11 GLN A 102
HIS A 125
GLU A 129
VAL A 144
THR A 215
THR A 216
 None
ZN  A   1 (-3.3A)
ZN  A   1 ( 4.7A)
None
MLT  A   3 ( 4.3A)
MLT  A   3 (-2.8A)
 1.16A 1jd0B-3q31A:
24.6		 1jd0B-3q31A:
26.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JD0_B_AZMB2401_1
(CARBONIC ANHYDRASE
XII)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		11 / 11 GLN A 121
HIS A 123
HIS A 125
GLU A 129
HIS A 142
VAL A 144
VAL A 154
LEU A 214
THR A 215
THR A 216
TRP A 225
 MLT  A   3 (-3.9A)
ZN  A   1 ( 3.2A)
ZN  A   1 (-3.3A)
ZN  A   1 ( 4.7A)
ZN  A   1 ( 3.2A)
None
MLT  A   3 (-4.6A)
MLT  A   3 ( 4.2A)
MLT  A   3 ( 4.3A)
MLT  A   3 (-2.8A)
MLT  A   3 (-4.9A)
 0.48A 1jd0B-3q31A:
24.6		 1jd0B-3q31A:
26.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JD0_B_AZMB2401_1
(CARBONIC ANHYDRASE
XII)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		7 / 11 HIS A 123
HIS A 142
VAL A 154
LEU A 214
THR A 215
THR A 216
TRP A 225
 ZN  A   1 ( 3.2A)
ZN  A   1 ( 3.2A)
MLT  A   3 (-4.6A)
MLT  A   3 ( 4.2A)
MLT  A   3 ( 4.3A)
MLT  A   3 (-2.8A)
MLT  A   3 (-4.9A)
 1.40A 1jd0B-3q31A:
24.6		 1jd0B-3q31A:
26.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L7F_A_BCZA801_1
(NEURAMINIDASE)		 3uk2 PANTOTHENATE
SYNTHETASE
(Burkholderia
thailandensis) 		3 / 3 ARG A 184
ARG A  69
ARG A 118
 MLT  A 284 (-3.1A)
None
MLT  A 284 (-3.3A)
 0.81A 1l7fA-3uk2A:
undetectable		 1l7fA-3uk2A:
19.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L7H_A_BCZA801_1
(NEURAMINIDASE)		 3uk2 PANTOTHENATE
SYNTHETASE
(Burkholderia
thailandensis) 		3 / 3 ARG A 184
ARG A  69
ARG A 118
 MLT  A 284 (-3.1A)
None
MLT  A 284 (-3.3A)
 0.84A 1l7hA-3uk2A:
undetectable		 1l7hA-3uk2A:
20.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NW5_A_SAMA401_1
(MODIFICATION
METHYLASE RSRI)		 3g1p PROTEIN PHNP
(Escherichia
coli) 		3 / 3 ASP A  80
HIS A 143
ASP A 187
 MLT  A 500 ( 2.8A)
MN  A 400 ( 3.4A)
None
 0.89A 1nw5A-3g1pA:
undetectable		 1nw5A-3g1pA:
22.68
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1O86_A_LPRA702_1
(ANGIOTENSIN
CONVERTING ENZYME)		 5a2r ANGIOTENSIN-CONVERTI
NG ENZYME
(Drosophila
melanogaster) 		11 / 12 GLN A 265
HIS A 337
HIS A 367
GLU A 368
HIS A 371
GLU A 395
PHE A 441
LYS A 495
HIS A 497
TYR A 504
TYR A 507
 MLT  A1615 (-3.2A)
MLT  A1615 (-3.8A)
ZN  A1616 (-3.2A)
MLT  A1615 (-4.3A)
ZN  A1616 (-3.3A)
ZN  A1616 (-2.4A)
MLT  A1615 ( 4.8A)
MLT  A1615 (-2.7A)
MLT  A1615 (-4.0A)
MLT  A1615 (-4.7A)
MLT  A1615 (-4.0A)
 0.25A 1o86A-5a2rA:
52.5		 1o86A-5a2rA:
44.76
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1O86_A_LPRA702_1
(ANGIOTENSIN
CONVERTING ENZYME)		 5a2r ANGIOTENSIN-CONVERTI
NG ENZYME
(Drosophila
melanogaster) 		9 / 12 GLU A 150
GLN A 265
HIS A 367
GLU A 395
PHE A 441
LYS A 495
HIS A 497
TYR A 504
TYR A 507
 None
MLT  A1615 (-3.2A)
ZN  A1616 (-3.2A)
ZN  A1616 (-2.4A)
MLT  A1615 ( 4.8A)
MLT  A1615 (-2.7A)
MLT  A1615 (-4.0A)
MLT  A1615 (-4.7A)
MLT  A1615 (-4.0A)
 0.83A 1o86A-5a2rA:
52.5		 1o86A-5a2rA:
44.76
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1O86_A_LPRA702_1
(ANGIOTENSIN
CONVERTING ENZYME)		 5a2r ANGIOTENSIN-CONVERTI
NG ENZYME
(Drosophila
melanogaster) 		6 / 12 HIS A 337
HIS A 367
GLU A 368
HIS A 371
PHE A 511
TYR A 507
 MLT  A1615 (-3.8A)
ZN  A1616 (-3.2A)
MLT  A1615 (-4.3A)
ZN  A1616 (-3.3A)
None
MLT  A1615 (-4.0A)
 1.30A 1o86A-5a2rA:
52.5		 1o86A-5a2rA:
44.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OE1_A_CUA502_0
(DISSIMILATORY
COPPER-CONTAINING
NITRITE REDUCTASE)		 3g1p PROTEIN PHNP
(Escherichia
coli) 		3 / 3 ASP A 164
HIS A 222
HIS A 200
 MN  A 401 (-2.1A)
MN  A 401 (-3.7A)
MLT  A 500 (-4.1A)
 0.59A 1oe1A-3g1pA:
undetectable		 1oe1A-3g1pA:
22.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OE3_A_CUA502_0
(DISSIMILATORY
COPPER-CONTAINING
NITRITE REDUCTASE)		 3g1p PROTEIN PHNP
(Escherichia
coli) 		3 / 3 ASP A 164
HIS A 222
HIS A 200
 MN  A 401 (-2.1A)
MN  A 401 (-3.7A)
MLT  A 500 (-4.1A)
 0.58A 1oe3A-3g1pA:
undetectable		 1oe3A-3g1pA:
22.01
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1OQ5_A_CELA701_1
(CARBONIC ANHYDRASE
II)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		8 / 12 GLN A 121
HIS A 123
HIS A 125
VAL A 144
LEU A 214
THR A 215
PRO A 218
TRP A 225
 MLT  A   3 (-3.9A)
ZN  A   1 ( 3.2A)
ZN  A   1 (-3.3A)
None
MLT  A   3 ( 4.2A)
MLT  A   3 ( 4.3A)
None
MLT  A   3 (-4.9A)
 0.46A 1oq5A-3q31A:
24.8		 1oq5A-3q31A:
30.69
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1OQ5_A_CELA701_1
(CARBONIC ANHYDRASE
II)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		5 / 12 GLU A  95
HIS A 123
HIS A 125
LEU A 214
THR A 215
 None
ZN  A   1 ( 3.2A)
ZN  A   1 (-3.3A)
MLT  A   3 ( 4.2A)
MLT  A   3 ( 4.3A)
 1.18A 1oq5A-3q31A:
24.8		 1oq5A-3q31A:
30.69
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1OQ5_A_CELA701_1
(CARBONIC ANHYDRASE
II)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		5 / 12 HIS A 125
VAL A 154
LEU A 214
THR A 215
PRO A 218
 ZN  A   1 (-3.3A)
MLT  A   3 (-4.6A)
MLT  A   3 ( 4.2A)
MLT  A   3 ( 4.3A)
None
 1.14A 1oq5A-3q31A:
24.8		 1oq5A-3q31A:
30.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PG2_A_ADNA552_1
(METHIONYL-TRNA
SYNTHETASE)		 3uk2 PANTOTHENATE
SYNTHETASE
(Burkholderia
thailandensis) 		6 / 11 HIS A  30
GLY A  32
HIS A  33
GLY A 144
ASP A 147
VAL A 173
 AMP  A 280 (-4.7A)
AMP  A 280 ( 3.9A)
AMP  A 280 (-4.0A)
AMP  A 280 (-3.3A)
MLT  A 284 ( 3.5A)
AMP  A 280 (-3.9A)
 0.83A 1pg2A-3uk2A:
undetectable		 1pg2A-3uk2A:
20.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QU2_A_MRCA1993_1
(ISOLEUCYL-TRNA
SYNTHETASE)		 3uk2 PANTOTHENATE
SYNTHETASE
(Burkholderia
thailandensis) 		6 / 12 HIS A  30
GLY A  32
HIS A  33
GLY A 144
ASP A 147
VAL A 173
 AMP  A 280 (-4.7A)
AMP  A 280 ( 3.9A)
AMP  A 280 (-4.0A)
AMP  A 280 (-3.3A)
MLT  A 284 ( 3.5A)
AMP  A 280 (-3.9A)
 0.96A 1qu2A-3uk2A:
2.5		 1qu2A-3uk2A:
14.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QU3_A_MRCA993_1
(ISOLEUCYL-TRNA
SYNTHETASE)		 3uk2 PANTOTHENATE
SYNTHETASE
(Burkholderia
thailandensis) 		5 / 12 HIS A  30
GLY A  32
HIS A  33
ASP A 147
VAL A 173
 AMP  A 280 (-4.7A)
AMP  A 280 ( 3.9A)
AMP  A 280 (-4.0A)
MLT  A 284 ( 3.5A)
AMP  A 280 (-3.9A)
 0.98A 1qu3A-3uk2A:
3.8		 1qu3A-3uk2A:
14.27
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1RJ6_A_AZMA400_1
(CARBONIC ANHYDRASE
XIV)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		6 / 10 GLN A 102
HIS A 123
HIS A 125
HIS A 142
THR A 215
THR A 216
 None
ZN  A   1 ( 3.2A)
ZN  A   1 (-3.3A)
ZN  A   1 ( 3.2A)
MLT  A   3 ( 4.3A)
MLT  A   3 (-2.8A)
 1.05A 1rj6A-3q31A:
24.7		 1rj6A-3q31A:
30.27
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1RJ6_A_AZMA400_1
(CARBONIC ANHYDRASE
XIV)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		9 / 10 GLN A 121
HIS A 123
HIS A 125
HIS A 142
VAL A 144
LEU A 214
THR A 215
THR A 216
TRP A 225
 MLT  A   3 (-3.9A)
ZN  A   1 ( 3.2A)
ZN  A   1 (-3.3A)
ZN  A   1 ( 3.2A)
None
MLT  A   3 ( 4.2A)
MLT  A   3 ( 4.3A)
MLT  A   3 (-2.8A)
MLT  A   3 (-4.9A)
 0.49A 1rj6A-3q31A:
24.7		 1rj6A-3q31A:
30.27
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1RJ6_A_AZMA400_1
(CARBONIC ANHYDRASE
XIV)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		6 / 10 GLN A 121
HIS A 123
HIS A 125
VAL A 144
LEU A 214
THR A 215
 MLT  A   3 (-3.9A)
ZN  A   1 ( 3.2A)
ZN  A   1 (-3.3A)
None
MLT  A   3 ( 4.2A)
MLT  A   3 ( 4.3A)
 1.45A 1rj6A-3q31A:
24.7		 1rj6A-3q31A:
30.27
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1RJ6_A_AZMA400_1
(CARBONIC ANHYDRASE
XIV)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		5 / 10 HIS A 123
HIS A 142
VAL A 155
LEU A  84
TRP A 225
 ZN  A   1 ( 3.2A)
ZN  A   1 ( 3.2A)
None
None
MLT  A   3 (-4.9A)
 1.40A 1rj6A-3q31A:
24.7		 1rj6A-3q31A:
30.27
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1RJ6_A_AZMA400_1
(CARBONIC ANHYDRASE
XIV)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		5 / 10 HIS A 125
VAL A 154
LEU A 214
THR A 215
THR A 216
 ZN  A   1 (-3.3A)
MLT  A   3 (-4.6A)
MLT  A   3 ( 4.2A)
MLT  A   3 ( 4.3A)
MLT  A   3 (-2.8A)
 0.82A 1rj6A-3q31A:
24.7		 1rj6A-3q31A:
30.27
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1RJ6_A_AZMA400_1
(CARBONIC ANHYDRASE
XIV)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		5 / 10 HIS A 142
HIS A 125
VAL A 154
LEU A 214
THR A 216
 ZN  A   1 ( 3.2A)
ZN  A   1 (-3.3A)
MLT  A   3 (-4.6A)
MLT  A   3 ( 4.2A)
MLT  A   3 (-2.8A)
 1.36A 1rj6A-3q31A:
24.7		 1rj6A-3q31A:
30.27
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1RJ6_B_AZMB401_1
(CARBONIC ANHYDRASE
XIV)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		6 / 10 GLN A 102
HIS A 123
HIS A 125
HIS A 142
THR A 215
THR A 216
 None
ZN  A   1 ( 3.2A)
ZN  A   1 (-3.3A)
ZN  A   1 ( 3.2A)
MLT  A   3 ( 4.3A)
MLT  A   3 (-2.8A)
 1.05A 1rj6B-3q31A:
24.5		 1rj6B-3q31A:
30.27
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1RJ6_B_AZMB401_1
(CARBONIC ANHYDRASE
XIV)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		9 / 10 GLN A 121
HIS A 123
HIS A 125
HIS A 142
VAL A 144
LEU A 214
THR A 215
THR A 216
TRP A 225
 MLT  A   3 (-3.9A)
ZN  A   1 ( 3.2A)
ZN  A   1 (-3.3A)
ZN  A   1 ( 3.2A)
None
MLT  A   3 ( 4.2A)
MLT  A   3 ( 4.3A)
MLT  A   3 (-2.8A)
MLT  A   3 (-4.9A)
 0.49A 1rj6B-3q31A:
24.5		 1rj6B-3q31A:
30.27
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1RJ6_B_AZMB401_1
(CARBONIC ANHYDRASE
XIV)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		6 / 10 GLN A 121
HIS A 123
HIS A 125
VAL A 144
LEU A 214
THR A 215
 MLT  A   3 (-3.9A)
ZN  A   1 ( 3.2A)
ZN  A   1 (-3.3A)
None
MLT  A   3 ( 4.2A)
MLT  A   3 ( 4.3A)
 1.46A 1rj6B-3q31A:
24.5		 1rj6B-3q31A:
30.27
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1RJ6_B_AZMB401_1
(CARBONIC ANHYDRASE
XIV)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		5 / 10 HIS A 123
HIS A 125
HIS A 142
LEU A 119
TRP A 225
 ZN  A   1 ( 3.2A)
ZN  A   1 (-3.3A)
ZN  A   1 ( 3.2A)
None
MLT  A   3 (-4.9A)
 1.39A 1rj6B-3q31A:
24.5		 1rj6B-3q31A:
30.27
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1RJ6_B_AZMB401_1
(CARBONIC ANHYDRASE
XIV)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		5 / 10 HIS A 123
HIS A 142
VAL A 155
LEU A  84
TRP A 225
 ZN  A   1 ( 3.2A)
ZN  A   1 ( 3.2A)
None
None
MLT  A   3 (-4.9A)
 1.35A 1rj6B-3q31A:
24.5		 1rj6B-3q31A:
30.27
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1RJ6_B_AZMB401_1
(CARBONIC ANHYDRASE
XIV)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		5 / 10 HIS A 125
VAL A 154
LEU A 214
THR A 215
THR A 216
 ZN  A   1 (-3.3A)
MLT  A   3 (-4.6A)
MLT  A   3 ( 4.2A)
MLT  A   3 ( 4.3A)
MLT  A   3 (-2.8A)
 0.82A 1rj6B-3q31A:
24.5		 1rj6B-3q31A:
30.27
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1RJ6_B_AZMB401_1
(CARBONIC ANHYDRASE
XIV)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		5 / 10 HIS A 142
HIS A 125
VAL A 154
LEU A 214
THR A 216
 ZN  A   1 ( 3.2A)
ZN  A   1 (-3.3A)
MLT  A   3 (-4.6A)
MLT  A   3 ( 4.2A)
MLT  A   3 (-2.8A)
 1.36A 1rj6B-3q31A:
24.5		 1rj6B-3q31A:
30.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RJD_A_SAMA801_0
(CARBOXY METHYL
TRANSFERASE FOR
PROTEIN PHOSPHATASE
2A CATALYTIC SUBUNIT)		 4nml RIBULOSE 5-PHOSPHATE
ISOMERASE
(Toxoplasma
gondii) 		5 / 12 ILE A 135
ASP A  91
ALA A  90
GLY A 233
GLY A 103
 None
MLT  A 303 (-4.5A)
None
None
CL  A 301 (-3.5A)
 1.04A 1rjdA-4nmlA:
undetectable		 1rjdA-4nmlA:
21.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RJD_B_SAMB802_0
(CARBOXY METHYL
TRANSFERASE FOR
PROTEIN PHOSPHATASE
2A CATALYTIC SUBUNIT)		 4nml RIBULOSE 5-PHOSPHATE
ISOMERASE
(Toxoplasma
gondii) 		5 / 12 ILE A 135
ASP A  91
ALA A  90
GLY A 233
GLY A 103
 None
MLT  A 303 (-4.5A)
None
None
CL  A 301 (-3.5A)
 1.02A 1rjdB-4nmlA:
undetectable		 1rjdB-4nmlA:
21.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RJD_C_SAMC803_0
(CARBOXY METHYL
TRANSFERASE FOR
PROTEIN PHOSPHATASE
2A CATALYTIC SUBUNIT)		 4nml RIBULOSE 5-PHOSPHATE
ISOMERASE
(Toxoplasma
gondii) 		5 / 12 ILE A 135
ASP A  91
ALA A  90
GLY A 233
GLY A 103
 None
MLT  A 303 (-4.5A)
None
None
CL  A 301 (-3.5A)
 1.03A 1rjdC-4nmlA:
undetectable		 1rjdC-4nmlA:
21.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T69_A_SHHA379_1
(HISTONE DEACETYLASE
8)		 3g1p PROTEIN PHNP
(Escherichia
coli) 		5 / 12 ASP A 103
HIS A  81
HIS A  76
ASP A  80
HIS A  78
 None
MN  A 401 (-3.5A)
MN  A 400 ( 3.4A)
MLT  A 500 ( 2.8A)
MN  A 400 ( 3.3A)
 1.43A 1t69A-3g1pA:
undetectable		 1t69A-3g1pA:
19.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V7Z_A_CRNA401_1
(CREATININE
AMIDOHYDROLASE)		 5a2r ANGIOTENSIN-CONVERTI
NG ENZYME
(Drosophila
melanogaster) 		4 / 8 GLU A 395
HIS A 367
HIS A 371
GLU A 368
 ZN  A1616 (-2.4A)
ZN  A1616 (-3.2A)
ZN  A1616 (-3.3A)
MLT  A1615 (-4.3A)
 0.81A 1v7zA-5a2rA:
undetectable		 1v7zA-5a2rA:
20.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V7Z_B_CRNB3401_1
(CREATININE
AMIDOHYDROLASE)		 5a2r ANGIOTENSIN-CONVERTI
NG ENZYME
(Drosophila
melanogaster) 		4 / 8 GLU A 395
HIS A 367
HIS A 371
GLU A 368
 ZN  A1616 (-2.4A)
ZN  A1616 (-3.2A)
ZN  A1616 (-3.3A)
MLT  A1615 (-4.3A)
 0.82A 1v7zB-5a2rA:
undetectable		 1v7zB-5a2rA:
20.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V7Z_C_CRNC4401_1
(CREATININE
AMIDOHYDROLASE)		 5a2r ANGIOTENSIN-CONVERTI
NG ENZYME
(Drosophila
melanogaster) 		4 / 8 GLU A 395
HIS A 367
HIS A 371
GLU A 368
 ZN  A1616 (-2.4A)
ZN  A1616 (-3.2A)
ZN  A1616 (-3.3A)
MLT  A1615 (-4.3A)
 0.82A 1v7zC-5a2rA:
undetectable		 1v7zC-5a2rA:
20.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V7Z_D_CRND5401_1
(CREATININE
AMIDOHYDROLASE)		 5a2r ANGIOTENSIN-CONVERTI
NG ENZYME
(Drosophila
melanogaster) 		4 / 8 GLU A 395
HIS A 367
HIS A 371
GLU A 368
 ZN  A1616 (-2.4A)
ZN  A1616 (-3.2A)
ZN  A1616 (-3.3A)
MLT  A1615 (-4.3A)
 0.84A 1v7zD-5a2rA:
undetectable		 1v7zD-5a2rA:
20.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V7Z_E_CRNE6401_1
(CREATININE
AMIDOHYDROLASE)		 5a2r ANGIOTENSIN-CONVERTI
NG ENZYME
(Drosophila
melanogaster) 		4 / 8 GLU A 395
HIS A 367
HIS A 371
GLU A 368
 ZN  A1616 (-2.4A)
ZN  A1616 (-3.2A)
ZN  A1616 (-3.3A)
MLT  A1615 (-4.3A)
 0.84A 1v7zE-5a2rA:
undetectable		 1v7zE-5a2rA:
20.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V7Z_F_CRNF7401_1
(CREATININE
AMIDOHYDROLASE)		 5a2r ANGIOTENSIN-CONVERTI
NG ENZYME
(Drosophila
melanogaster) 		4 / 8 GLU A 395
HIS A 367
HIS A 371
GLU A 368
 ZN  A1616 (-2.4A)
ZN  A1616 (-3.2A)
ZN  A1616 (-3.3A)
MLT  A1615 (-4.3A)
 0.83A 1v7zF-5a2rA:
undetectable		 1v7zF-5a2rA:
20.57
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1YDA_A_AZMA264_1
(CARBONIC ANHYDRASE
II)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		8 / 10 GLN A 121
HIS A 123
HIS A 142
VAL A 144
VAL A 154
THR A 215
THR A 216
TRP A 225
 MLT  A   3 (-3.9A)
ZN  A   1 ( 3.2A)
ZN  A   1 ( 3.2A)
None
MLT  A   3 (-4.6A)
MLT  A   3 ( 4.3A)
MLT  A   3 (-2.8A)
MLT  A   3 (-4.9A)
 0.44A 1ydaA-3q31A:
24.1		 1ydaA-3q31A:
30.32
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1YDB_A_AZMA264_1
(CARBONIC ANHYDRASE
II)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		6 / 11 GLN A 102
HIS A 123
HIS A 125
VAL A 144
THR A 215
THR A 216
 None
ZN  A   1 ( 3.2A)
ZN  A   1 (-3.3A)
None
MLT  A   3 ( 4.3A)
MLT  A   3 (-2.8A)
 1.18A 1ydbA-3q31A:
24.3		 1ydbA-3q31A:
30.32
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1YDB_A_AZMA264_1
(CARBONIC ANHYDRASE
II)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		9 / 11 GLN A 121
HIS A 123
HIS A 125
HIS A 142
VAL A 144
VAL A 154
THR A 215
THR A 216
TRP A 225
 MLT  A   3 (-3.9A)
ZN  A   1 ( 3.2A)
ZN  A   1 (-3.3A)
ZN  A   1 ( 3.2A)
None
MLT  A   3 (-4.6A)
MLT  A   3 ( 4.3A)
MLT  A   3 (-2.8A)
MLT  A   3 (-4.9A)
 0.38A 1ydbA-3q31A:
24.3		 1ydbA-3q31A:
30.32
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1YDB_A_AZMA264_1
(CARBONIC ANHYDRASE
II)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		5 / 11 GLN A 121
HIS A 123
HIS A 125
VAL A 144
THR A 215
 MLT  A   3 (-3.9A)
ZN  A   1 ( 3.2A)
ZN  A   1 (-3.3A)
None
MLT  A   3 ( 4.3A)
 1.22A 1ydbA-3q31A:
24.3		 1ydbA-3q31A:
30.32
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1YDD_A_AZMA264_1
(CARBONIC ANHYDRASE
II)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		6 / 10 GLN A 102
HIS A 123
HIS A 125
HIS A 142
THR A 215
THR A 216
 None
ZN  A   1 ( 3.2A)
ZN  A   1 (-3.3A)
ZN  A   1 ( 3.2A)
MLT  A   3 ( 4.3A)
MLT  A   3 (-2.8A)
 1.06A 1yddA-3q31A:
24.4		 1yddA-3q31A:
30.32
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1YDD_A_AZMA264_1
(CARBONIC ANHYDRASE
II)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		5 / 10 GLN A 102
HIS A 125
VAL A 144
THR A 215
THR A 216
 None
ZN  A   1 (-3.3A)
None
MLT  A   3 ( 4.3A)
MLT  A   3 (-2.8A)
 1.16A 1yddA-3q31A:
24.4		 1yddA-3q31A:
30.32
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1YDD_A_AZMA264_1
(CARBONIC ANHYDRASE
II)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		8 / 10 GLN A 121
HIS A 123
HIS A 125
HIS A 142
VAL A 144
VAL A 154
THR A 215
THR A 216
 MLT  A   3 (-3.9A)
ZN  A   1 ( 3.2A)
ZN  A   1 (-3.3A)
ZN  A   1 ( 3.2A)
None
MLT  A   3 (-4.6A)
MLT  A   3 ( 4.3A)
MLT  A   3 (-2.8A)
 0.37A 1yddA-3q31A:
24.4		 1yddA-3q31A:
30.32
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1YDD_A_AZMA264_1
(CARBONIC ANHYDRASE
II)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		5 / 10 GLN A 121
HIS A 123
HIS A 125
VAL A 144
THR A 215
 MLT  A   3 (-3.9A)
ZN  A   1 ( 3.2A)
ZN  A   1 (-3.3A)
None
MLT  A   3 ( 4.3A)
 1.21A 1yddA-3q31A:
24.4		 1yddA-3q31A:
30.32
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1Z9Y_A_FUNA500_1
(CARBONIC ANHYDRASE
II)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		6 / 12 GLN A 102
HIS A 123
HIS A 125
LEU A 214
THR A 215
THR A 216
 None
ZN  A   1 ( 3.2A)
ZN  A   1 (-3.3A)
MLT  A   3 ( 4.2A)
MLT  A   3 ( 4.3A)
MLT  A   3 (-2.8A)
 1.16A 1z9yA-3q31A:
24.6		 1z9yA-3q31A:
30.69
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1Z9Y_A_FUNA500_1
(CARBONIC ANHYDRASE
II)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		6 / 12 GLN A 102
HIS A 125
VAL A 144
LEU A 214
THR A 215
THR A 216
 None
ZN  A   1 (-3.3A)
None
MLT  A   3 ( 4.2A)
MLT  A   3 ( 4.3A)
MLT  A   3 (-2.8A)
 1.35A 1z9yA-3q31A:
24.6		 1z9yA-3q31A:
30.69
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1Z9Y_A_FUNA500_1
(CARBONIC ANHYDRASE
II)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		6 / 12 GLN A 121
HIS A 123
HIS A 125
VAL A 144
LEU A 214
THR A 215
 MLT  A   3 (-3.9A)
ZN  A   1 ( 3.2A)
ZN  A   1 (-3.3A)
None
MLT  A   3 ( 4.2A)
MLT  A   3 ( 4.3A)
 1.42A 1z9yA-3q31A:
24.6		 1z9yA-3q31A:
30.69
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1Z9Y_A_FUNA500_1
(CARBONIC ANHYDRASE
II)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		9 / 12 GLN A 121
HIS A 123
HIS A 125
VAL A 144
VAL A 154
LEU A 214
THR A 215
THR A 216
TRP A 225
 MLT  A   3 (-3.9A)
ZN  A   1 ( 3.2A)
ZN  A   1 (-3.3A)
None
MLT  A   3 (-4.6A)
MLT  A   3 ( 4.2A)
MLT  A   3 ( 4.3A)
MLT  A   3 (-2.8A)
MLT  A   3 (-4.9A)
 0.40A 1z9yA-3q31A:
24.6		 1z9yA-3q31A:
30.69
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ZGF_A_TRUA300_1
(CARBONIC ANHYDRASE
II)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		6 / 12 GLN A 102
HIS A 123
HIS A 125
HIS A 142
THR A 215
THR A 216
 None
ZN  A   1 ( 3.2A)
ZN  A   1 (-3.3A)
ZN  A   1 ( 3.2A)
MLT  A   3 ( 4.3A)
MLT  A   3 (-2.8A)
 1.03A 1zgfA-3q31A:
24.7		 1zgfA-3q31A:
30.69
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ZGF_A_TRUA300_1
(CARBONIC ANHYDRASE
II)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		5 / 12 GLN A 102
HIS A 125
VAL A 144
THR A 215
THR A 216
 None
ZN  A   1 (-3.3A)
None
MLT  A   3 ( 4.3A)
MLT  A   3 (-2.8A)
 1.13A 1zgfA-3q31A:
24.7		 1zgfA-3q31A:
30.69
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ZGF_A_TRUA300_1
(CARBONIC ANHYDRASE
II)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		10 / 12 GLN A 121
HIS A 123
HIS A 125
HIS A 142
VAL A 144
VAL A 154
LEU A 214
THR A 215
THR A 216
TRP A 225
 MLT  A   3 (-3.9A)
ZN  A   1 ( 3.2A)
ZN  A   1 (-3.3A)
ZN  A   1 ( 3.2A)
None
MLT  A   3 (-4.6A)
MLT  A   3 ( 4.2A)
MLT  A   3 ( 4.3A)
MLT  A   3 (-2.8A)
MLT  A   3 (-4.9A)
 0.37A 1zgfA-3q31A:
24.7		 1zgfA-3q31A:
30.69
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ZSB_A_AZMA264_1
(CARBONIC ANHYDRASE
II)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		7 / 12 GLN A 102
HIS A 123
HIS A 125
GLU A 129
HIS A 142
THR A 215
THR A 216
 None
ZN  A   1 ( 3.2A)
ZN  A   1 (-3.3A)
ZN  A   1 ( 4.7A)
ZN  A   1 ( 3.2A)
MLT  A   3 ( 4.3A)
MLT  A   3 (-2.8A)
 0.96A 1zsbA-3q31A:
24.4		 1zsbA-3q31A:
30.32
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ZSB_A_AZMA264_1
(CARBONIC ANHYDRASE
II)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		6 / 12 GLN A 102
HIS A 125
GLU A 129
VAL A 144
THR A 215
THR A 216
 None
ZN  A   1 (-3.3A)
ZN  A   1 ( 4.7A)
None
MLT  A   3 ( 4.3A)
MLT  A   3 (-2.8A)
 1.17A 1zsbA-3q31A:
24.4		 1zsbA-3q31A:
30.32
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ZSB_A_AZMA264_1
(CARBONIC ANHYDRASE
II)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		7 / 12 GLN A 121
HIS A 123
GLU A 140
HIS A 142
VAL A 144
VAL A 154
TRP A 225
 MLT  A   3 (-3.9A)
ZN  A   1 ( 3.2A)
None
ZN  A   1 ( 3.2A)
None
MLT  A   3 (-4.6A)
MLT  A   3 (-4.9A)
 1.47A 1zsbA-3q31A:
24.4		 1zsbA-3q31A:
30.32
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ZSB_A_AZMA264_1
(CARBONIC ANHYDRASE
II)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		11 / 12 GLN A 121
HIS A 123
HIS A 125
GLU A 129
HIS A 142
VAL A 144
VAL A 154
LEU A 214
THR A 215
THR A 216
TRP A 225
 MLT  A   3 (-3.9A)
ZN  A   1 ( 3.2A)
ZN  A   1 (-3.3A)
ZN  A   1 ( 4.7A)
ZN  A   1 ( 3.2A)
None
MLT  A   3 (-4.6A)
MLT  A   3 ( 4.2A)
MLT  A   3 ( 4.3A)
MLT  A   3 (-2.8A)
MLT  A   3 (-4.9A)
 0.42A 1zsbA-3q31A:
24.4		 1zsbA-3q31A:
30.32
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ZSB_A_AZMA264_1
(CARBONIC ANHYDRASE
II)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		6 / 12 GLN A 121
HIS A 123
HIS A 125
VAL A 144
LEU A 214
THR A 215
 MLT  A   3 (-3.9A)
ZN  A   1 ( 3.2A)
ZN  A   1 (-3.3A)
None
MLT  A   3 ( 4.2A)
MLT  A   3 ( 4.3A)
 1.48A 1zsbA-3q31A:
24.4		 1zsbA-3q31A:
30.32
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ZSB_A_AZMA264_1
(CARBONIC ANHYDRASE
II)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		7 / 12 HIS A 123
HIS A 142
VAL A 154
LEU A 214
THR A 215
THR A 216
TRP A 225
 ZN  A   1 ( 3.2A)
ZN  A   1 ( 3.2A)
MLT  A   3 (-4.6A)
MLT  A   3 ( 4.2A)
MLT  A   3 ( 4.3A)
MLT  A   3 (-2.8A)
MLT  A   3 (-4.9A)
 1.45A 1zsbA-3q31A:
24.4		 1zsbA-3q31A:
30.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AOI_C_FRDC305_1
(POL POLYPROTEIN
PEPTIDE INHIBITOR)		 3og9 PROTEIN YAHD A
COPPER INDUCIBLE
HYDROLASE
(Lactococcus
lactis) 		4 / 5 GLY A  65
PRO A 161
VAL A 160
ILE A 159
 None
None
None
MLT  A 500 ( 4.6A)
 0.98A 2aoiA-3og9A:
undetectable		 2aoiA-3og9A:
19.05
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2AW1_A_COXA264_1
(CARBONIC ANHYDRASE
II)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		6 / 12 GLN A 121
HIS A 123
HIS A 125
VAL A 144
LEU A 214
THR A 215
 MLT  A   3 (-3.9A)
ZN  A   1 ( 3.2A)
ZN  A   1 (-3.3A)
None
MLT  A   3 ( 4.2A)
MLT  A   3 ( 4.3A)
 1.42A 2aw1A-3q31A:
24.8		 2aw1A-3q31A:
30.69
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2AW1_A_COXA264_1
(CARBONIC ANHYDRASE
II)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		9 / 12 GLN A 121
HIS A 123
HIS A 125
VAL A 144
VAL A 154
LEU A 214
THR A 215
THR A 216
TRP A 225
 MLT  A   3 (-3.9A)
ZN  A   1 ( 3.2A)
ZN  A   1 (-3.3A)
None
MLT  A   3 (-4.6A)
MLT  A   3 ( 4.2A)
MLT  A   3 ( 4.3A)
MLT  A   3 (-2.8A)
MLT  A   3 (-4.9A)
 0.39A 2aw1A-3q31A:
24.8		 2aw1A-3q31A:
30.69
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2C6N_A_LPRA705_1
(ANGIOTENSIN-CONVERTI
NG ENZYME, SOMATIC
ISOFORM)		 5a2r ANGIOTENSIN-CONVERTI
NG ENZYME
(Drosophila
melanogaster) 		12 / 12 GLN A 265
HIS A 337
ALA A 338
GLN A 361
HIS A 367
GLU A 368
HIS A 371
GLU A 395
LYS A 495
HIS A 497
TYR A 504
TYR A 507
 MLT  A1615 (-3.2A)
MLT  A1615 (-3.8A)
MLT  A1615 ( 4.9A)
None
ZN  A1616 (-3.2A)
MLT  A1615 (-4.3A)
ZN  A1616 (-3.3A)
ZN  A1616 (-2.4A)
MLT  A1615 (-2.7A)
MLT  A1615 (-4.0A)
MLT  A1615 (-4.7A)
MLT  A1615 (-4.0A)
 0.56A 2c6nA-5a2rA:
49.9		 2c6nA-5a2rA:
40.90
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2C6N_A_LPRA705_1
(ANGIOTENSIN-CONVERTI
NG ENZYME, SOMATIC
ISOFORM)		 5a2r ANGIOTENSIN-CONVERTI
NG ENZYME
(Drosophila
melanogaster) 		8 / 12 HIS A 337
ALA A 338
HIS A 371
GLU A 368
GLU A 395
HIS A 497
TYR A 504
TYR A 507
 MLT  A1615 (-3.8A)
MLT  A1615 ( 4.9A)
ZN  A1616 (-3.3A)
MLT  A1615 (-4.3A)
ZN  A1616 (-2.4A)
MLT  A1615 (-4.0A)
MLT  A1615 (-4.7A)
MLT  A1615 (-4.0A)
 1.48A 2c6nA-5a2rA:
49.9		 2c6nA-5a2rA:
40.90
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2C6N_A_LPRA705_1
(ANGIOTENSIN-CONVERTI
NG ENZYME, SOMATIC
ISOFORM)		 5a2r ANGIOTENSIN-CONVERTI
NG ENZYME
(Drosophila
melanogaster) 		6 / 12 HIS A 337
GLN A 353
HIS A 371
HIS A 497
TYR A 504
TYR A 507
 MLT  A1615 (-3.8A)
None
ZN  A1616 (-3.3A)
MLT  A1615 (-4.0A)
MLT  A1615 (-4.7A)
MLT  A1615 (-4.0A)
 1.30A 2c6nA-5a2rA:
49.9		 2c6nA-5a2rA:
40.90
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2C6N_A_LPRA705_1
(ANGIOTENSIN-CONVERTI
NG ENZYME, SOMATIC
ISOFORM)		 5a2r ANGIOTENSIN-CONVERTI
NG ENZYME
(Drosophila
melanogaster) 		6 / 12 HIS A 337
GLN A 353
LYS A 495
HIS A 497
TYR A 504
TYR A 507
 MLT  A1615 (-3.8A)
None
MLT  A1615 (-2.7A)
MLT  A1615 (-4.0A)
MLT  A1615 (-4.7A)
MLT  A1615 (-4.0A)
 1.24A 2c6nA-5a2rA:
49.9		 2c6nA-5a2rA:
40.90
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2C6N_B_LPRB705_1
(ANGIOTENSIN-CONVERTI
NG ENZYME, SOMATIC
ISOFORM)		 5a2r ANGIOTENSIN-CONVERTI
NG ENZYME
(Drosophila
melanogaster) 		10 / 12 GLN A 265
HIS A 337
HIS A 367
GLU A 368
HIS A 371
GLU A 395
LYS A 495
HIS A 497
TYR A 504
TYR A 507
 MLT  A1615 (-3.2A)
MLT  A1615 (-3.8A)
ZN  A1616 (-3.2A)
MLT  A1615 (-4.3A)
ZN  A1616 (-3.3A)
ZN  A1616 (-2.4A)
MLT  A1615 (-2.7A)
MLT  A1615 (-4.0A)
MLT  A1615 (-4.7A)
MLT  A1615 (-4.0A)
 0.36A 2c6nB-5a2rA:
50.1		 2c6nB-5a2rA:
40.90
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2C6N_B_LPRB705_1
(ANGIOTENSIN-CONVERTI
NG ENZYME, SOMATIC
ISOFORM)		 5a2r ANGIOTENSIN-CONVERTI
NG ENZYME
(Drosophila
melanogaster) 		5 / 12 HIS A 497
HIS A 371
GLU A 395
GLU A 368
HIS A 337
 MLT  A1615 (-4.0A)
ZN  A1616 (-3.3A)
ZN  A1616 (-2.4A)
MLT  A1615 (-4.3A)
MLT  A1615 (-3.8A)
 1.35A 2c6nB-5a2rA:
50.1		 2c6nB-5a2rA:
40.90
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2EZ7_A_DHIA301_0
(CARBONIC ANHYDRASE 2)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		4 / 6 HIS A 125
GLN A 121
THR A 215
PRO A 217
 ZN  A   1 (-3.3A)
MLT  A   3 (-3.9A)
MLT  A   3 ( 4.3A)
None
 1.13A 2ez7A-3q31A:
24.4		 2ez7A-3q31A:
30.69
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2GEH_A_NHYA300_1
(CARBONIC ANHYDRASE 2)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		8 / 8 HIS A 123
HIS A 125
HIS A 142
VAL A 144
VAL A 154
LEU A 214
THR A 215
TRP A 225
 ZN  A   1 ( 3.2A)
ZN  A   1 (-3.3A)
ZN  A   1 ( 3.2A)
None
MLT  A   3 (-4.6A)
MLT  A   3 ( 4.2A)
MLT  A   3 ( 4.3A)
MLT  A   3 (-4.9A)
 0.38A 2gehA-3q31A:
24.6		 2gehA-3q31A:
30.69
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2GEH_A_NHYA300_1
(CARBONIC ANHYDRASE 2)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		4 / 8 HIS A 125
VAL A 144
LEU A 214
THR A 215
 ZN  A   1 (-3.3A)
None
MLT  A   3 ( 4.2A)
MLT  A   3 ( 4.3A)
 0.91A 2gehA-3q31A:
24.6		 2gehA-3q31A:
30.69
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2H4N_A_AZMA264_1
(CARBONIC ANHYDRASE
II)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		5 / 9 GLN A 102
HIS A 125
HIS A 142
THR A 215
THR A 216
 None
ZN  A   1 (-3.3A)
ZN  A   1 ( 3.2A)
MLT  A   3 ( 4.3A)
MLT  A   3 (-2.8A)
 0.92A 2h4nA-3q31A:
24.4		 2h4nA-3q31A:
30.32
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2H4N_A_AZMA264_1
(CARBONIC ANHYDRASE
II)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		7 / 9 GLN A 121
HIS A 125
HIS A 142
VAL A 144
THR A 215
THR A 216
TRP A 225
 MLT  A   3 (-3.9A)
ZN  A   1 (-3.3A)
ZN  A   1 ( 3.2A)
None
MLT  A   3 ( 4.3A)
MLT  A   3 (-2.8A)
MLT  A   3 (-4.9A)
 0.52A 2h4nA-3q31A:
24.4		 2h4nA-3q31A:
30.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IT4_A_PPFA500_1
(CARBONIC ANHYDRASE 1)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		6 / 8 HIS A 123
HIS A 125
HIS A 142
VAL A 154
LEU A 214
THR A 215
 ZN  A   1 ( 3.2A)
ZN  A   1 (-3.3A)
ZN  A   1 ( 3.2A)
MLT  A   3 (-4.6A)
MLT  A   3 ( 4.2A)
MLT  A   3 ( 4.3A)
 0.36A 2it4A-3q31A:
23.5		 2it4A-3q31A:
28.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IT4_A_PPFA500_1
(CARBONIC ANHYDRASE 1)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		5 / 8 HIS A 125
HIS A 142
VAL A 144
LEU A 214
THR A 215
 ZN  A   1 (-3.3A)
ZN  A   1 ( 3.2A)
None
MLT  A   3 ( 4.2A)
MLT  A   3 ( 4.3A)
 1.11A 2it4A-3q31A:
23.5		 2it4A-3q31A:
28.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JIH_B_097B1001_1
(ADAMTS-1)		 5a2r ANGIOTENSIN-CONVERTI
NG ENZYME
(Drosophila
melanogaster) 		4 / 8 THR A 364
HIS A 367
GLU A 368
HIS A 371
 None
ZN  A1616 (-3.2A)
MLT  A1615 (-4.3A)
ZN  A1616 (-3.3A)
 0.25A 2jihB-5a2rA:
undetectable		 2jihB-5a2rA:
19.13
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2OXT_B_SAMB300_1
(NUCLEOSIDE-2'-O-METH
YLTRANSFERASE)		 5ikm NS5 METHYL
TRANSFERASE
(Dengue
virus) 		5 / 5 SER A  56
GLY A  86
HIS A 110
ASP A 131
ASP A 146
 SAM  A 311 ( 2.7A)
SAM  A 311 (-3.3A)
SAM  A 311 (-4.1A)
MLT  A 313 ( 2.6A)
SAM  A 311 (-3.8A)
 0.50A 2oxtB-5ikmA:
39.0		 2oxtB-5ikmA:
49.63
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2OXT_C_SAMC300_1
(NUCLEOSIDE-2'-O-METH
YLTRANSFERASE)		 5ikm NS5 METHYL
TRANSFERASE
(Dengue
virus) 		4 / 4 SER A  56
GLY A  58
HIS A 110
ASP A 131
 SAM  A 311 ( 2.7A)
SAM  A 311 (-3.3A)
SAM  A 311 (-4.1A)
MLT  A 313 ( 2.6A)
 0.61A 2oxtC-5ikmA:
38.7		 2oxtC-5ikmA:
49.63
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2POU_A_I7AA1000_1
(CARBONIC ANHYDRASE 2)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		5 / 12 GLN A 102
HIS A 123
HIS A 125
THR A 215
THR A 216
 None
ZN  A   1 ( 3.2A)
ZN  A   1 (-3.3A)
MLT  A   3 ( 4.3A)
MLT  A   3 (-2.8A)
 1.12A 2pouA-3q31A:
24.7		 2pouA-3q31A:
30.69
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2POU_A_I7AA1000_1
(CARBONIC ANHYDRASE 2)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		5 / 12 GLN A 102
HIS A 125
VAL A 144
THR A 215
THR A 216
 None
ZN  A   1 (-3.3A)
None
MLT  A   3 ( 4.3A)
MLT  A   3 (-2.8A)
 1.13A 2pouA-3q31A:
24.7		 2pouA-3q31A:
30.69
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2POU_A_I7AA1000_1
(CARBONIC ANHYDRASE 2)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		9 / 12 GLN A 121
HIS A 123
HIS A 125
VAL A 144
VAL A 154
LEU A 214
THR A 215
THR A 216
TRP A 225
 MLT  A   3 (-3.9A)
ZN  A   1 ( 3.2A)
ZN  A   1 (-3.3A)
None
MLT  A   3 (-4.6A)
MLT  A   3 ( 4.2A)
MLT  A   3 ( 4.3A)
MLT  A   3 (-2.8A)
MLT  A   3 (-4.9A)
 0.40A 2pouA-3q31A:
24.7		 2pouA-3q31A:
30.69
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2POU_A_I7AA1000_1
(CARBONIC ANHYDRASE 2)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		6 / 12 HIS A 142
HIS A 125
VAL A 154
LEU A 214
THR A 215
THR A 216
 ZN  A   1 ( 3.2A)
ZN  A   1 (-3.3A)
MLT  A   3 (-4.6A)
MLT  A   3 ( 4.2A)
MLT  A   3 ( 4.3A)
MLT  A   3 (-2.8A)
 1.33A 2pouA-3q31A:
24.7		 2pouA-3q31A:
30.69
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2PXC_A_SAMA500_0
(GENOME POLYPROTEIN
[CONTAINS: CAPSID
PROTEIN C (CORE
PROTEIN)
ENVELOPE PROTEIN M
(MATRIX PROTEIN)
MAJOR ENVELOPE
PROTEIN E
NON-STRUCTURAL
PROTEIN 1 (NS1)
NON-STRUCTURAL
PROTEIN 2A (NS2A)
FLAVIVIRIN PROTEASE
NS2B REGULATORY
SUBUNIT
FLAVIVIRIN PROTEASE
NS3 CATALYTIC
SUBUNIT
NON-STRUCTURAL
PROTEIN 4A (NS4A)
NON-STRUCTURAL
PROTEIN 4B (NS4B)
RNA-DIRECTED RNA
POLYMERASE (EC
2.7.7.48) (NS5)])		 5ikm NS5 METHYL
TRANSFERASE
(Dengue
virus) 		11 / 12 GLY A  58
GLY A  81
GLY A  83
GLY A  86
TRP A  87
THR A 104
LYS A 105
ASP A 131
VAL A 132
ASP A 146
ILE A 147
 SAM  A 311 (-3.3A)
SAM  A 311 (-3.2A)
SAM  A 311 (-3.3A)
SAM  A 311 (-3.3A)
SAM  A 311 (-3.5A)
SAM  A 311 (-4.5A)
MLT  A 313 ( 3.0A)
MLT  A 313 ( 2.6A)
SAM  A 311 (-3.7A)
SAM  A 311 (-3.8A)
SAM  A 311 ( 4.3A)
 0.38A 2pxcA-5ikmA:
41.3		 2pxcA-5ikmA:
61.96
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2PXC_A_SAMA500_0
(GENOME POLYPROTEIN
[CONTAINS: CAPSID
PROTEIN C (CORE
PROTEIN)
ENVELOPE PROTEIN M
(MATRIX PROTEIN)
MAJOR ENVELOPE
PROTEIN E
NON-STRUCTURAL
PROTEIN 1 (NS1)
NON-STRUCTURAL
PROTEIN 2A (NS2A)
FLAVIVIRIN PROTEASE
NS2B REGULATORY
SUBUNIT
FLAVIVIRIN PROTEASE
NS3 CATALYTIC
SUBUNIT
NON-STRUCTURAL
PROTEIN 4A (NS4A)
NON-STRUCTURAL
PROTEIN 4B (NS4B)
RNA-DIRECTED RNA
POLYMERASE (EC
2.7.7.48) (NS5)])		 5ikm NS5 METHYL
TRANSFERASE
(Dengue
virus) 		9 / 12 GLY A  58
GLY A  81
GLY A  83
GLY A  86
TRP A  87
THR A 104
LYS A 105
GLU A 111
ASP A 146
 SAM  A 311 (-3.3A)
SAM  A 311 (-3.2A)
SAM  A 311 (-3.3A)
SAM  A 311 (-3.3A)
SAM  A 311 (-3.5A)
SAM  A 311 (-4.5A)
MLT  A 313 ( 3.0A)
None
SAM  A 311 (-3.8A)
 0.73A 2pxcA-5ikmA:
41.3		 2pxcA-5ikmA:
61.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q0J_B_BEZB500_0
(QUINOLONE SIGNAL
RESPONSE PROTEIN)		 3g1p PROTEIN PHNP
(Escherichia
coli) 		5 / 11 ASP A  80
HIS A  81
HIS A 143
ASP A 164
HIS A 222
 MLT  A 500 ( 2.8A)
MN  A 401 (-3.5A)
MN  A 400 ( 3.4A)
MN  A 401 (-2.1A)
MN  A 401 (-3.7A)
 0.96A 2q0jB-3g1pA:
10.5		 2q0jB-3g1pA:
20.23
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2WA2_A_SAMA1248_0
(NON-STRUCTURAL
PROTEIN 5)		 5ikm NS5 METHYL
TRANSFERASE
(Dengue
virus) 		8 / 12 GLY A  58
GLY A  81
GLY A  83
TRP A  87
THR A 104
ASP A 131
VAL A 132
ILE A 147
 SAM  A 311 (-3.3A)
SAM  A 311 (-3.2A)
SAM  A 311 (-3.3A)
SAM  A 311 (-3.5A)
SAM  A 311 (-4.5A)
MLT  A 313 ( 2.6A)
SAM  A 311 (-3.7A)
SAM  A 311 ( 4.3A)
 0.42A 2wa2A-5ikmA:
33.1		 2wa2A-5ikmA:
50.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2WA2_A_SAMA1248_0
(NON-STRUCTURAL
PROTEIN 5)		 5ikm NS5 METHYL
TRANSFERASE
(Dengue
virus) 		7 / 12 GLY A  81
GLY A  83
THR A 104
GLU A 111
ASP A 131
VAL A 132
ILE A 147
 SAM  A 311 (-3.2A)
SAM  A 311 (-3.3A)
SAM  A 311 (-4.5A)
None
MLT  A 313 ( 2.6A)
SAM  A 311 (-3.7A)
SAM  A 311 ( 4.3A)
 0.67A 2wa2A-5ikmA:
33.1		 2wa2A-5ikmA:
50.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X1L_A_ADNA601_1
(METHIONYL-TRNA
SYNTHETASE)		 3uk2 PANTOTHENATE
SYNTHETASE
(Burkholderia
thailandensis) 		5 / 11 HIS A  30
GLY A  32
HIS A  33
GLY A 144
ASP A 147
 AMP  A 280 (-4.7A)
AMP  A 280 ( 3.9A)
AMP  A 280 (-4.0A)
AMP  A 280 (-3.3A)
MLT  A 284 ( 3.5A)
 0.85A 2x1lA-3uk2A:
4.7		 2x1lA-3uk2A:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X1L_B_ADNB601_1
(METHIONYL-TRNA
SYNTHETASE)		 3uk2 PANTOTHENATE
SYNTHETASE
(Burkholderia
thailandensis) 		5 / 12 HIS A  30
GLY A  32
HIS A  33
GLY A 144
ASP A 147
 AMP  A 280 (-4.7A)
AMP  A 280 ( 3.9A)
AMP  A 280 (-4.0A)
AMP  A 280 (-3.3A)
MLT  A 284 ( 3.5A)
 0.79A 2x1lB-3uk2A:
undetectable		 2x1lB-3uk2A:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X1L_C_ADNC601_1
(METHIONYL-TRNA
SYNTHETASE)		 3uk2 PANTOTHENATE
SYNTHETASE
(Burkholderia
thailandensis) 		5 / 11 HIS A  30
GLY A  32
HIS A  33
GLY A 144
ASP A 147
 AMP  A 280 (-4.7A)
AMP  A 280 ( 3.9A)
AMP  A 280 (-4.0A)
AMP  A 280 (-3.3A)
MLT  A 284 ( 3.5A)
 0.82A 2x1lC-3uk2A:
undetectable		 2x1lC-3uk2A:
21.03
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2X8Z_A_X8ZA1615_1
(ANGIOTENSIN
CONVERTING ENZYME)		 5a2r ANGIOTENSIN-CONVERTI
NG ENZYME
(Drosophila
melanogaster) 		11 / 11 GLN A 265
HIS A 337
HIS A 367
GLU A 368
HIS A 371
GLU A 395
PHE A 441
LYS A 495
HIS A 497
TYR A 504
TYR A 507
 MLT  A1615 (-3.2A)
MLT  A1615 (-3.8A)
ZN  A1616 (-3.2A)
MLT  A1615 (-4.3A)
ZN  A1616 (-3.3A)
ZN  A1616 (-2.4A)
MLT  A1615 ( 4.8A)
MLT  A1615 (-2.7A)
MLT  A1615 (-4.0A)
MLT  A1615 (-4.7A)
MLT  A1615 (-4.0A)
 0.16A 2x8zA-5a2rA:
60.8		 2x8zA-5a2rA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2X8Z_A_X8ZA1615_1
(ANGIOTENSIN
CONVERTING ENZYME)		 5a2r ANGIOTENSIN-CONVERTI
NG ENZYME
(Drosophila
melanogaster) 		7 / 11 HIS A 337
HIS A 367
GLU A 368
HIS A 371
GLU A 395
PHE A 511
TYR A 507
 MLT  A1615 (-3.8A)
ZN  A1616 (-3.2A)
MLT  A1615 (-4.3A)
ZN  A1616 (-3.3A)
ZN  A1616 (-2.4A)
None
MLT  A1615 (-4.0A)
 1.31A 2x8zA-5a2rA:
60.8		 2x8zA-5a2rA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2X91_A_LPRA1615_1
(ANGIOTENSIN
CONVERTING ENZYME)		 5a2r ANGIOTENSIN-CONVERTI
NG ENZYME
(Drosophila
melanogaster) 		12 / 12 GLN A 265
HIS A 337
HIS A 367
GLU A 368
HIS A 371
GLU A 395
LYS A 495
TYR A 496
HIS A 497
VAL A 502
TYR A 504
TYR A 507
 MLT  A1615 (-3.2A)
MLT  A1615 (-3.8A)
ZN  A1616 (-3.2A)
MLT  A1615 (-4.3A)
ZN  A1616 (-3.3A)
ZN  A1616 (-2.4A)
MLT  A1615 (-2.7A)
None
MLT  A1615 (-4.0A)
None
MLT  A1615 (-4.7A)
MLT  A1615 (-4.0A)
 0.19A 2x91A-5a2rA:
61.0		 2x91A-5a2rA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2X91_A_LPRA1615_2
(ANGIOTENSIN
CONVERTING ENZYME)		 5a2r ANGIOTENSIN-CONVERTI
NG ENZYME
(Drosophila
melanogaster) 		3 / 3 SER A 339
THR A 364
PHE A 441
 None
None
MLT  A1615 ( 4.8A)
 0.09A 2x91A-5a2rA:
61.0		 2x91A-5a2rA:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XXG_A_CUA1338_0
(DISSIMILATORY
COPPER-CONTAINING
NITRITE REDUCTASE)		 3g1p PROTEIN PHNP
(Escherichia
coli) 		3 / 3 ASP A 164
HIS A 222
HIS A 200
 MN  A 401 (-2.1A)
MN  A 401 (-3.7A)
MLT  A 500 (-4.1A)
 0.60A 2xxgA-3g1pA:
undetectable		 2xxgA-3g1pA:
22.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XXG_C_CUC1339_0
(DISSIMILATORY
COPPER-CONTAINING
NITRITE REDUCTASE)		 3g1p PROTEIN PHNP
(Escherichia
coli) 		3 / 3 ASP A 164
HIS A 222
HIS A 200
 MN  A 401 (-2.1A)
MN  A 401 (-3.7A)
MLT  A 500 (-4.1A)
 0.64A 2xxgC-3g1pA:
undetectable		 2xxgC-3g1pA:
22.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y7H_B_SAMB530_1
(TYPE I RESTRICTION
ENZYME ECOKI M
PROTEIN)		 2fgq OUTER MEMBRANE PORIN
PROTEIN 32
(Delftia
acidovorans) 		3 / 3 TYR X 171
GLU X 205
THR X 102
 None
None
MLT  X 700 (-2.9A)
 0.83A 2y7hB-2fgqX:
undetectable		 2y7hB-2fgqX:
21.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A6J_A_CRNA303_1
(CREATININE
AMIDOHYDROLASE)		 5a2r ANGIOTENSIN-CONVERTI
NG ENZYME
(Drosophila
melanogaster) 		4 / 8 GLU A 395
HIS A 367
HIS A 371
GLU A 368
 ZN  A1616 (-2.4A)
ZN  A1616 (-3.2A)
ZN  A1616 (-3.3A)
MLT  A1615 (-4.3A)
 0.81A 3a6jA-5a2rA:
undetectable		 3a6jA-5a2rA:
20.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A6J_B_CRNB304_1
(CREATININE
AMIDOHYDROLASE)		 5a2r ANGIOTENSIN-CONVERTI
NG ENZYME
(Drosophila
melanogaster) 		4 / 7 GLU A 395
HIS A 367
HIS A 371
GLU A 368
 ZN  A1616 (-2.4A)
ZN  A1616 (-3.2A)
ZN  A1616 (-3.3A)
MLT  A1615 (-4.3A)
 0.78A 3a6jB-5a2rA:
undetectable		 3a6jB-5a2rA:
20.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A6J_C_CRNC305_1
(CREATININE
AMIDOHYDROLASE)		 5a2r ANGIOTENSIN-CONVERTI
NG ENZYME
(Drosophila
melanogaster) 		4 / 8 GLU A 395
HIS A 367
HIS A 371
GLU A 368
 ZN  A1616 (-2.4A)
ZN  A1616 (-3.2A)
ZN  A1616 (-3.3A)
MLT  A1615 (-4.3A)
 0.79A 3a6jC-5a2rA:
undetectable		 3a6jC-5a2rA:
20.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A6J_E_CRNE306_1
(CREATININE
AMIDOHYDROLASE)		 5a2r ANGIOTENSIN-CONVERTI
NG ENZYME
(Drosophila
melanogaster) 		4 / 8 GLU A 395
HIS A 367
HIS A 371
GLU A 368
 ZN  A1616 (-2.4A)
ZN  A1616 (-3.2A)
ZN  A1616 (-3.3A)
MLT  A1615 (-4.3A)
 0.82A 3a6jE-5a2rA:
undetectable		 3a6jE-5a2rA:
20.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A6J_F_CRNF307_1
(CREATININE
AMIDOHYDROLASE)		 5a2r ANGIOTENSIN-CONVERTI
NG ENZYME
(Drosophila
melanogaster) 		4 / 8 GLU A 395
HIS A 367
HIS A 371
GLU A 368
 ZN  A1616 (-2.4A)
ZN  A1616 (-3.2A)
ZN  A1616 (-3.3A)
MLT  A1615 (-4.3A)
 0.78A 3a6jF-5a2rA:
undetectable		 3a6jF-5a2rA:
20.37
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3BL1_A_BL1A300_1
(CARBONIC ANHYDRASE 2)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		6 / 12 GLN A 102
HIS A 123
HIS A 125
HIS A 142
THR A 215
THR A 216
 None
ZN  A   1 ( 3.2A)
ZN  A   1 (-3.3A)
ZN  A   1 ( 3.2A)
MLT  A   3 ( 4.3A)
MLT  A   3 (-2.8A)
 1.07A 3bl1A-3q31A:
24.5		 3bl1A-3q31A:
30.69
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3BL1_A_BL1A300_1
(CARBONIC ANHYDRASE 2)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		5 / 12 GLN A 102
HIS A 125
VAL A 144
THR A 215
THR A 216
 None
ZN  A   1 (-3.3A)
None
MLT  A   3 ( 4.3A)
MLT  A   3 (-2.8A)
 1.10A 3bl1A-3q31A:
24.5		 3bl1A-3q31A:
30.69
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3BL1_A_BL1A300_1
(CARBONIC ANHYDRASE 2)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		9 / 12 GLN A 121
HIS A 123
HIS A 125
HIS A 142
VAL A 154
LEU A 214
THR A 215
THR A 216
TRP A 225
 MLT  A   3 (-3.9A)
ZN  A   1 ( 3.2A)
ZN  A   1 (-3.3A)
ZN  A   1 ( 3.2A)
MLT  A   3 (-4.6A)
MLT  A   3 ( 4.2A)
MLT  A   3 ( 4.3A)
MLT  A   3 (-2.8A)
MLT  A   3 (-4.9A)
 0.40A 3bl1A-3q31A:
24.5		 3bl1A-3q31A:
30.69
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3BL1_A_BL1A300_1
(CARBONIC ANHYDRASE 2)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		5 / 12 HIS A 125
VAL A 144
LEU A 214
THR A 215
THR A 216
 ZN  A   1 (-3.3A)
None
MLT  A   3 ( 4.2A)
MLT  A   3 ( 4.3A)
MLT  A   3 (-2.8A)
 1.08A 3bl1A-3q31A:
24.5		 3bl1A-3q31A:
30.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3C0Z_C_SHHC301_1
(HISTONE DEACETYLASE
7A)		 3g1p PROTEIN PHNP
(Escherichia
coli) 		5 / 6 ASP A 103
HIS A  81
HIS A  76
ASP A  80
HIS A  78
 None
MN  A 401 (-3.5A)
MN  A 400 ( 3.4A)
MLT  A 500 ( 2.8A)
MN  A 400 ( 3.3A)
 1.36A 3c0zC-3g1pA:
undetectable		 3c0zC-3g1pA:
20.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3CAJ_A_EZLA265_1
(CARBONIC ANHYDRASE 2)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		9 / 10 HIS A 123
HIS A 125
HIS A 142
VAL A 144
LEU A 214
THR A 215
THR A 216
PRO A 218
TRP A 225
 ZN  A   1 ( 3.2A)
ZN  A   1 (-3.3A)
ZN  A   1 ( 3.2A)
None
MLT  A   3 ( 4.2A)
MLT  A   3 ( 4.3A)
MLT  A   3 (-2.8A)
None
MLT  A   3 (-4.9A)
 0.43A 3cajA-3q31A:
24.7		 3cajA-3q31A:
30.69
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3CAJ_A_EZLA265_1
(CARBONIC ANHYDRASE 2)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		6 / 10 HIS A 123
HIS A 142
LEU A 214
THR A 216
PRO A 218
TRP A 225
 ZN  A   1 ( 3.2A)
ZN  A   1 ( 3.2A)
MLT  A   3 ( 4.2A)
MLT  A   3 (-2.8A)
None
MLT  A   3 (-4.9A)
 1.41A 3cajA-3q31A:
24.7		 3cajA-3q31A:
30.69
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3CAJ_A_EZLA265_1
(CARBONIC ANHYDRASE 2)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		5 / 10 HIS A 123
HIS A 142
THR A 215
PRO A 217
TRP A 225
 ZN  A   1 ( 3.2A)
ZN  A   1 ( 3.2A)
MLT  A   3 ( 4.3A)
None
MLT  A   3 (-4.9A)
 1.27A 3cajA-3q31A:
24.7		 3cajA-3q31A:
30.69
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3CAJ_A_EZLA265_1
(CARBONIC ANHYDRASE 2)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		5 / 10 HIS A 125
VAL A 154
LEU A 214
THR A 215
THR A 216
 ZN  A   1 (-3.3A)
MLT  A   3 (-4.6A)
MLT  A   3 ( 4.2A)
MLT  A   3 ( 4.3A)
MLT  A   3 (-2.8A)
 0.88A 3cajA-3q31A:
24.7		 3cajA-3q31A:
30.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CZV_A_AZMA263_1
(CARBONIC ANHYDRASE
13)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		5 / 12 GLN A 102
HIS A 123
HIS A 125
HIS A 142
THR A 215
 None
ZN  A   1 ( 3.2A)
ZN  A   1 (-3.3A)
ZN  A   1 ( 3.2A)
MLT  A   3 ( 4.3A)
 0.87A 3czvA-3q31A:
24.3
3czvB-3q31A:
24.4		 3czvA-3q31A:
27.97
3czvB-3q31A:
27.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CZV_A_AZMA263_1
(CARBONIC ANHYDRASE
13)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		5 / 12 GLN A 102
HIS A 123
HIS A 125
VAL A 144
THR A 215
 None
ZN  A   1 ( 3.2A)
ZN  A   1 (-3.3A)
None
MLT  A   3 ( 4.3A)
 1.10A 3czvA-3q31A:
24.3
3czvB-3q31A:
24.4		 3czvA-3q31A:
27.97
3czvB-3q31A:
27.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CZV_A_AZMA263_1
(CARBONIC ANHYDRASE
13)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		9 / 12 GLN A 121
HIS A 123
HIS A 125
HIS A 142
VAL A 144
VAL A 154
LEU A 214
THR A 215
TRP A 225
 MLT  A   3 (-3.9A)
ZN  A   1 ( 3.2A)
ZN  A   1 (-3.3A)
ZN  A   1 ( 3.2A)
None
MLT  A   3 (-4.6A)
MLT  A   3 ( 4.2A)
MLT  A   3 ( 4.3A)
MLT  A   3 (-4.9A)
 0.60A 3czvA-3q31A:
24.3
3czvB-3q31A:
24.4		 3czvA-3q31A:
27.97
3czvB-3q31A:
27.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CZV_A_AZMA263_1
(CARBONIC ANHYDRASE
13)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		5 / 12 HIS A 123
HIS A 125
VAL A 144
LEU A 214
THR A 215
 ZN  A   1 ( 3.2A)
ZN  A   1 (-3.3A)
None
MLT  A   3 ( 4.2A)
MLT  A   3 ( 4.3A)
 1.15A 3czvA-3q31A:
24.3
3czvB-3q31A:
24.4		 3czvA-3q31A:
27.97
3czvB-3q31A:
27.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CZV_B_AZMB263_1
(CARBONIC ANHYDRASE
13)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		5 / 10 GLN A 102
HIS A 123
HIS A 125
HIS A 142
THR A 215
 None
ZN  A   1 ( 3.2A)
ZN  A   1 (-3.3A)
ZN  A   1 ( 3.2A)
MLT  A   3 ( 4.3A)
 0.95A 3czvB-3q31A:
24.4		 3czvB-3q31A:
27.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CZV_B_AZMB263_1
(CARBONIC ANHYDRASE
13)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		5 / 10 GLN A 102
HIS A 123
HIS A 125
VAL A 144
THR A 215
 None
ZN  A   1 ( 3.2A)
ZN  A   1 (-3.3A)
None
MLT  A   3 ( 4.3A)
 1.15A 3czvB-3q31A:
24.4		 3czvB-3q31A:
27.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CZV_B_AZMB263_1
(CARBONIC ANHYDRASE
13)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		9 / 10 GLN A 121
HIS A 123
HIS A 125
HIS A 142
VAL A 144
VAL A 154
LEU A 214
THR A 215
TRP A 225
 MLT  A   3 (-3.9A)
ZN  A   1 ( 3.2A)
ZN  A   1 (-3.3A)
ZN  A   1 ( 3.2A)
None
MLT  A   3 (-4.6A)
MLT  A   3 ( 4.2A)
MLT  A   3 ( 4.3A)
MLT  A   3 (-4.9A)
 0.54A 3czvB-3q31A:
24.4		 3czvB-3q31A:
27.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CZV_B_AZMB263_1
(CARBONIC ANHYDRASE
13)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		5 / 10 HIS A 123
HIS A 125
VAL A 144
LEU A 214
THR A 215
 ZN  A   1 ( 3.2A)
ZN  A   1 (-3.3A)
None
MLT  A   3 ( 4.2A)
MLT  A   3 ( 4.3A)
 1.17A 3czvB-3q31A:
24.4		 3czvB-3q31A:
27.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CZV_B_AZMB263_1
(CARBONIC ANHYDRASE
13)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		5 / 10 HIS A 123
HIS A 142
VAL A 154
LEU A 214
TRP A 225
 ZN  A   1 ( 3.2A)
ZN  A   1 ( 3.2A)
MLT  A   3 (-4.6A)
MLT  A   3 ( 4.2A)
MLT  A   3 (-4.9A)
 1.47A 3czvB-3q31A:
24.4		 3czvB-3q31A:
27.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CZV_B_AZMB263_1
(CARBONIC ANHYDRASE
13)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		5 / 10 HIS A 125
HIS A 123
VAL A 144
LEU A 214
THR A 215
 ZN  A   1 (-3.3A)
ZN  A   1 ( 3.2A)
None
MLT  A   3 ( 4.2A)
MLT  A   3 ( 4.3A)
 1.45A 3czvB-3q31A:
24.4		 3czvB-3q31A:
27.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CZV_B_AZMB263_1
(CARBONIC ANHYDRASE
13)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		5 / 10 HIS A 142
HIS A 125
VAL A 154
LEU A 214
THR A 215
 ZN  A   1 ( 3.2A)
ZN  A   1 (-3.3A)
MLT  A   3 (-4.6A)
MLT  A   3 ( 4.2A)
MLT  A   3 ( 4.3A)
 1.33A 3czvB-3q31A:
24.4		 3czvB-3q31A:
27.97
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3DAZ_A_MZMA263_1
(CARBONIC ANHYDRASE 2)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		6 / 10 GLN A 102
HIS A 123
HIS A 125
HIS A 142
THR A 215
THR A 216
 None
ZN  A   1 ( 3.2A)
ZN  A   1 (-3.3A)
ZN  A   1 ( 3.2A)
MLT  A   3 ( 4.3A)
MLT  A   3 (-2.8A)
 1.06A 3dazA-3q31A:
24.4		 3dazA-3q31A:
30.69
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3DAZ_A_MZMA263_1
(CARBONIC ANHYDRASE 2)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		9 / 10 GLN A 121
HIS A 123
HIS A 125
HIS A 142
VAL A 144
LEU A 214
THR A 215
THR A 216
TRP A 225
 MLT  A   3 (-3.9A)
ZN  A   1 ( 3.2A)
ZN  A   1 (-3.3A)
ZN  A   1 ( 3.2A)
None
MLT  A   3 ( 4.2A)
MLT  A   3 ( 4.3A)
MLT  A   3 (-2.8A)
MLT  A   3 (-4.9A)
 0.40A 3dazA-3q31A:
24.4		 3dazA-3q31A:
30.69
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3DAZ_A_MZMA263_1
(CARBONIC ANHYDRASE 2)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		6 / 10 GLN A 121
HIS A 123
HIS A 125
VAL A 144
LEU A 214
THR A 215
 MLT  A   3 (-3.9A)
ZN  A   1 ( 3.2A)
ZN  A   1 (-3.3A)
None
MLT  A   3 ( 4.2A)
MLT  A   3 ( 4.3A)
 1.48A 3dazA-3q31A:
24.4		 3dazA-3q31A:
30.69
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3DAZ_A_MZMA263_1
(CARBONIC ANHYDRASE 2)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		6 / 10 HIS A 123
HIS A 142
LEU A 214
THR A 215
THR A 216
TRP A 225
 ZN  A   1 ( 3.2A)
ZN  A   1 ( 3.2A)
MLT  A   3 ( 4.2A)
MLT  A   3 ( 4.3A)
MLT  A   3 (-2.8A)
MLT  A   3 (-4.9A)
 1.46A 3dazA-3q31A:
24.4		 3dazA-3q31A:
30.69
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3DAZ_A_MZMA263_1
(CARBONIC ANHYDRASE 2)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		5 / 10 HIS A 125
VAL A 154
LEU A 214
THR A 215
THR A 216
 ZN  A   1 (-3.3A)
MLT  A   3 (-4.6A)
MLT  A   3 ( 4.2A)
MLT  A   3 ( 4.3A)
MLT  A   3 (-2.8A)
 0.90A 3dazA-3q31A:
24.4		 3dazA-3q31A:
30.69
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3DAZ_A_MZMA263_1
(CARBONIC ANHYDRASE 2)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		5 / 10 HIS A 142
HIS A 125
VAL A 154
LEU A 214
THR A 216
 ZN  A   1 ( 3.2A)
ZN  A   1 (-3.3A)
MLT  A   3 (-4.6A)
MLT  A   3 ( 4.2A)
MLT  A   3 (-2.8A)
 1.34A 3dazA-3q31A:
24.4		 3dazA-3q31A:
30.69
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3DC3_A_AZMA263_1
(CARBONIC ANHYDRASE 2)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		7 / 12 GLN A 102
HIS A 123
HIS A 125
GLU A 129
HIS A 142
THR A 215
THR A 216
 None
ZN  A   1 ( 3.2A)
ZN  A   1 (-3.3A)
ZN  A   1 ( 4.7A)
ZN  A   1 ( 3.2A)
MLT  A   3 ( 4.3A)
MLT  A   3 (-2.8A)
 0.97A 3dc3A-3q31A:
24.4		 3dc3A-3q31A:
31.05
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3DC3_A_AZMA263_1
(CARBONIC ANHYDRASE 2)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		6 / 12 GLN A 102
HIS A 125
GLU A 129
VAL A 144
THR A 215
THR A 216
 None
ZN  A   1 (-3.3A)
ZN  A   1 ( 4.7A)
None
MLT  A   3 ( 4.3A)
MLT  A   3 (-2.8A)
 1.18A 3dc3A-3q31A:
24.4		 3dc3A-3q31A:
31.05
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3DC3_A_AZMA263_1
(CARBONIC ANHYDRASE 2)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		11 / 12 GLN A 121
HIS A 123
HIS A 125
GLU A 129
HIS A 142
VAL A 144
VAL A 154
LEU A 214
THR A 215
THR A 216
TRP A 225
 MLT  A   3 (-3.9A)
ZN  A   1 ( 3.2A)
ZN  A   1 (-3.3A)
ZN  A   1 ( 4.7A)
ZN  A   1 ( 3.2A)
None
MLT  A   3 (-4.6A)
MLT  A   3 ( 4.2A)
MLT  A   3 ( 4.3A)
MLT  A   3 (-2.8A)
MLT  A   3 (-4.9A)
 0.42A 3dc3A-3q31A:
24.4		 3dc3A-3q31A:
31.05
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3DC3_A_AZMA263_1
(CARBONIC ANHYDRASE 2)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		6 / 12 GLN A 121
HIS A 123
HIS A 125
VAL A 144
LEU A 214
THR A 215
 MLT  A   3 (-3.9A)
ZN  A   1 ( 3.2A)
ZN  A   1 (-3.3A)
None
MLT  A   3 ( 4.2A)
MLT  A   3 ( 4.3A)
 1.48A 3dc3A-3q31A:
24.4		 3dc3A-3q31A:
31.05
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3DC3_A_AZMA263_1
(CARBONIC ANHYDRASE 2)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		7 / 12 HIS A 123
HIS A 142
VAL A 154
LEU A 214
THR A 215
THR A 216
TRP A 225
 ZN  A   1 ( 3.2A)
ZN  A   1 ( 3.2A)
MLT  A   3 (-4.6A)
MLT  A   3 ( 4.2A)
MLT  A   3 ( 4.3A)
MLT  A   3 (-2.8A)
MLT  A   3 (-4.9A)
 1.41A 3dc3A-3q31A:
24.4		 3dc3A-3q31A:
31.05
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3DC3_A_AZMA263_1
(CARBONIC ANHYDRASE 2)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		6 / 12 HIS A 125
GLU A 129
VAL A 144
LEU A 214
THR A 215
THR A 216
 ZN  A   1 (-3.3A)
ZN  A   1 ( 4.7A)
None
MLT  A   3 ( 4.2A)
MLT  A   3 ( 4.3A)
MLT  A   3 (-2.8A)
 1.11A 3dc3A-3q31A:
24.4		 3dc3A-3q31A:
31.05
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3DCS_A_MZMA263_1
(CARBONIC ANHYDRASE 2)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		6 / 10 GLN A 102
HIS A 123
HIS A 125
HIS A 142
THR A 215
THR A 216
 None
ZN  A   1 ( 3.2A)
ZN  A   1 (-3.3A)
ZN  A   1 ( 3.2A)
MLT  A   3 ( 4.3A)
MLT  A   3 (-2.8A)
 0.97A 3dcsA-3q31A:
24.4		 3dcsA-3q31A:
31.05
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3DCS_A_MZMA263_1
(CARBONIC ANHYDRASE 2)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		9 / 10 GLN A 121
HIS A 123
HIS A 125
HIS A 142
VAL A 144
LEU A 214
THR A 215
THR A 216
TRP A 225
 MLT  A   3 (-3.9A)
ZN  A   1 ( 3.2A)
ZN  A   1 (-3.3A)
ZN  A   1 ( 3.2A)
None
MLT  A   3 ( 4.2A)
MLT  A   3 ( 4.3A)
MLT  A   3 (-2.8A)
MLT  A   3 (-4.9A)
 0.47A 3dcsA-3q31A:
24.4		 3dcsA-3q31A:
31.05
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3DCS_A_MZMA263_1
(CARBONIC ANHYDRASE 2)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		6 / 10 HIS A 123
HIS A 142
LEU A 214
THR A 215
THR A 216
TRP A 225
 ZN  A   1 ( 3.2A)
ZN  A   1 ( 3.2A)
MLT  A   3 ( 4.2A)
MLT  A   3 ( 4.3A)
MLT  A   3 (-2.8A)
MLT  A   3 (-4.9A)
 1.44A 3dcsA-3q31A:
24.4		 3dcsA-3q31A:
31.05
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3DCS_A_MZMA263_1
(CARBONIC ANHYDRASE 2)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		5 / 10 HIS A 125
VAL A 154
LEU A 214
THR A 215
THR A 216
 ZN  A   1 (-3.3A)
MLT  A   3 (-4.6A)
MLT  A   3 ( 4.2A)
MLT  A   3 ( 4.3A)
MLT  A   3 (-2.8A)
 0.92A 3dcsA-3q31A:
24.4		 3dcsA-3q31A:
31.05
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3DCS_A_MZMA263_1
(CARBONIC ANHYDRASE 2)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		5 / 10 HIS A 142
HIS A 125
VAL A 154
LEU A 214
THR A 216
 ZN  A   1 ( 3.2A)
ZN  A   1 (-3.3A)
MLT  A   3 (-4.6A)
MLT  A   3 ( 4.2A)
MLT  A   3 (-2.8A)
 1.31A 3dcsA-3q31A:
24.4		 3dcsA-3q31A:
31.05
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3DCW_A_EZLA301_1
(CARBONIC ANHYDRASE 2)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		10 / 10 HIS A 123
HIS A 125
HIS A 142
VAL A 144
VAL A 154
LEU A 214
THR A 215
THR A 216
PRO A 218
TRP A 225
 ZN  A   1 ( 3.2A)
ZN  A   1 (-3.3A)
ZN  A   1 ( 3.2A)
None
MLT  A   3 (-4.6A)
MLT  A   3 ( 4.2A)
MLT  A   3 ( 4.3A)
MLT  A   3 (-2.8A)
None
MLT  A   3 (-4.9A)
 0.42A 3dcwA-3q31A:
24.5		 3dcwA-3q31A:
31.05
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3DCW_A_EZLA301_1
(CARBONIC ANHYDRASE 2)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		7 / 10 HIS A 123
HIS A 142
VAL A 144
LEU A 214
THR A 215
PRO A 217
TRP A 225
 ZN  A   1 ( 3.2A)
ZN  A   1 ( 3.2A)
None
MLT  A   3 ( 4.2A)
MLT  A   3 ( 4.3A)
None
MLT  A   3 (-4.9A)
 1.35A 3dcwA-3q31A:
24.5		 3dcwA-3q31A:
31.05
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3DCW_A_EZLA301_1
(CARBONIC ANHYDRASE 2)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		8 / 10 HIS A 123
HIS A 142
VAL A 154
LEU A 214
THR A 215
THR A 216
PRO A 218
TRP A 225
 ZN  A   1 ( 3.2A)
ZN  A   1 ( 3.2A)
MLT  A   3 (-4.6A)
MLT  A   3 ( 4.2A)
MLT  A   3 ( 4.3A)
MLT  A   3 (-2.8A)
None
MLT  A   3 (-4.9A)
 1.34A 3dcwA-3q31A:
24.5		 3dcwA-3q31A:
31.05
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3DCW_A_EZLA301_1
(CARBONIC ANHYDRASE 2)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		6 / 10 HIS A 125
HIS A 123
VAL A 144
LEU A 214
THR A 215
PRO A 218
 ZN  A   1 (-3.3A)
ZN  A   1 ( 3.2A)
None
MLT  A   3 ( 4.2A)
MLT  A   3 ( 4.3A)
None
 1.46A 3dcwA-3q31A:
24.5		 3dcwA-3q31A:
31.05
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3DD0_A_EZLA301_1
(CARBONIC ANHYDRASE 2)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		10 / 10 HIS A 123
HIS A 125
HIS A 142
VAL A 144
VAL A 154
LEU A 214
THR A 215
THR A 216
PRO A 218
TRP A 225
 ZN  A   1 ( 3.2A)
ZN  A   1 (-3.3A)
ZN  A   1 ( 3.2A)
None
MLT  A   3 (-4.6A)
MLT  A   3 ( 4.2A)
MLT  A   3 ( 4.3A)
MLT  A   3 (-2.8A)
None
MLT  A   3 (-4.9A)
 0.41A 3dd0A-3q31A:
24.4		 3dd0A-3q31A:
30.69
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3DD0_A_EZLA301_1
(CARBONIC ANHYDRASE 2)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		7 / 10 HIS A 123
HIS A 142
VAL A 144
LEU A 214
THR A 215
PRO A 217
TRP A 225
 ZN  A   1 ( 3.2A)
ZN  A   1 ( 3.2A)
None
MLT  A   3 ( 4.2A)
MLT  A   3 ( 4.3A)
None
MLT  A   3 (-4.9A)
 1.36A 3dd0A-3q31A:
24.4		 3dd0A-3q31A:
30.69
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3DD0_A_EZLA301_1
(CARBONIC ANHYDRASE 2)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		8 / 10 HIS A 123
HIS A 142
VAL A 154
LEU A 214
THR A 215
THR A 216
PRO A 218
TRP A 225
 ZN  A   1 ( 3.2A)
ZN  A   1 ( 3.2A)
MLT  A   3 (-4.6A)
MLT  A   3 ( 4.2A)
MLT  A   3 ( 4.3A)
MLT  A   3 (-2.8A)
None
MLT  A   3 (-4.9A)
 1.37A 3dd0A-3q31A:
24.4		 3dd0A-3q31A:
30.69
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3DD0_A_EZLA301_1
(CARBONIC ANHYDRASE 2)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		6 / 10 HIS A 125
HIS A 123
VAL A 144
LEU A 214
THR A 215
PRO A 218
 ZN  A   1 (-3.3A)
ZN  A   1 ( 3.2A)
None
MLT  A   3 ( 4.2A)
MLT  A   3 ( 4.3A)
None
 1.46A 3dd0A-3q31A:
24.4		 3dd0A-3q31A:
30.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3E9X_A_NIMA1_1
(LACTOTRANSFERRIN')		 4a29 ENGINEERED
RETRO-ALDOL ENZYME
RA95.0
(synthetic
construct) 		4 / 4 GLU A  53
GLY A  91
THR A  84
GLU A  86
 MLT  A 300 (-3.0A)
None
None
None
 0.99A 3e9xA-4a29A:
undetectable		 3e9xA-4a29A:
22.61
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3F4X_A_KLTA300_1
(CARBONIC ANHYDRASE 2)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		10 / 12 GLN A 121
HIS A 123
HIS A 125
VAL A 144
VAL A 154
LEU A 214
THR A 215
THR A 216
PRO A 218
TRP A 225
 MLT  A   3 (-3.9A)
ZN  A   1 ( 3.2A)
ZN  A   1 (-3.3A)
None
MLT  A   3 (-4.6A)
MLT  A   3 ( 4.2A)
MLT  A   3 ( 4.3A)
MLT  A   3 (-2.8A)
None
MLT  A   3 (-4.9A)
 0.44A 3f4xA-3q31A:
24.3		 3f4xA-3q31A:
30.69
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3F4X_A_KLTA300_1
(CARBONIC ANHYDRASE 2)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		6 / 12 HIS A 123
VAL A 154
LEU A 214
THR A 216
PRO A 218
TRP A 225
 ZN  A   1 ( 3.2A)
MLT  A   3 (-4.6A)
MLT  A   3 ( 4.2A)
MLT  A   3 (-2.8A)
None
MLT  A   3 (-4.9A)
 1.35A 3f4xA-3q31A:
24.3		 3f4xA-3q31A:
30.69
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3FW3_A_ETSA302_1
(CARBONIC ANHYDRASE 4)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		9 / 12 GLN A 121
HIS A 123
HIS A 125
VAL A 144
VAL A 154
LEU A 214
THR A 215
THR A 216
TRP A 225
 MLT  A   3 (-3.9A)
ZN  A   1 ( 3.2A)
ZN  A   1 (-3.3A)
None
MLT  A   3 (-4.6A)
MLT  A   3 ( 4.2A)
MLT  A   3 ( 4.3A)
MLT  A   3 (-2.8A)
MLT  A   3 (-4.9A)
 0.48A 3fw3A-3q31A:
24.4		 3fw3A-3q31A:
30.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3FW3_A_ETSA302_1
(CARBONIC ANHYDRASE 4)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		6 / 12 HIS A 123
VAL A 154
LEU A 214
THR A 215
THR A 216
TRP A 225
 ZN  A   1 ( 3.2A)
MLT  A   3 (-4.6A)
MLT  A   3 ( 4.2A)
MLT  A   3 ( 4.3A)
MLT  A   3 (-2.8A)
MLT  A   3 (-4.9A)
 1.31A 3fw3A-3q31A:
24.4		 3fw3A-3q31A:
30.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3FW3_B_ETSB303_1
(CARBONIC ANHYDRASE 4)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		6 / 12 GLN A 102
HIS A 123
HIS A 125
HIS A 142
THR A 215
THR A 216
 None
ZN  A   1 ( 3.2A)
ZN  A   1 (-3.3A)
ZN  A   1 ( 3.2A)
MLT  A   3 ( 4.3A)
MLT  A   3 (-2.8A)
 1.08A 3fw3B-3q31A:
24.3		 3fw3B-3q31A:
30.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3FW3_B_ETSB303_1
(CARBONIC ANHYDRASE 4)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		10 / 12 GLN A 121
HIS A 123
HIS A 125
HIS A 142
VAL A 144
VAL A 154
LEU A 214
THR A 215
THR A 216
TRP A 225
 MLT  A   3 (-3.9A)
ZN  A   1 ( 3.2A)
ZN  A   1 (-3.3A)
ZN  A   1 ( 3.2A)
None
MLT  A   3 (-4.6A)
MLT  A   3 ( 4.2A)
MLT  A   3 ( 4.3A)
MLT  A   3 (-2.8A)
MLT  A   3 (-4.9A)
 0.39A 3fw3B-3q31A:
24.3		 3fw3B-3q31A:
30.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3FW3_B_ETSB303_1
(CARBONIC ANHYDRASE 4)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		7 / 12 HIS A 123
HIS A 142
VAL A 154
LEU A 214
THR A 215
THR A 216
TRP A 225
 ZN  A   1 ( 3.2A)
ZN  A   1 ( 3.2A)
MLT  A   3 (-4.6A)
MLT  A   3 ( 4.2A)
MLT  A   3 ( 4.3A)
MLT  A   3 (-2.8A)
MLT  A   3 (-4.9A)
 1.41A 3fw3B-3q31A:
24.3		 3fw3B-3q31A:
30.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G2O_A_SAMA500_1
(PCZA361.24)		 2gq3 MALATE SYNTHASE G
(Mycobacterium
tuberculosis) 		3 / 3 ARG A 339
GLU A 360
ASP A 280
 MLT  A 900 (-2.9A)
None
None
 0.88A 3g2oA-2gq3A:
undetectable		 3g2oA-2gq3A:
18.58
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3GCZ_A_SAMA4633_0
(POLYPROTEIN)		 5ikm NS5 METHYL
TRANSFERASE
(Dengue
virus) 		11 / 12 SER A  56
GLY A  58
GLY A  81
GLY A  83
GLY A  86
TRP A  87
THR A 104
ASP A 131
VAL A 132
ASP A 146
ILE A 147
 SAM  A 311 ( 2.7A)
SAM  A 311 (-3.3A)
SAM  A 311 (-3.2A)
SAM  A 311 (-3.3A)
SAM  A 311 (-3.3A)
SAM  A 311 (-3.5A)
SAM  A 311 (-4.5A)
MLT  A 313 ( 2.6A)
SAM  A 311 (-3.7A)
SAM  A 311 (-3.8A)
SAM  A 311 ( 4.3A)
 0.37A 3gczA-5ikmA:
40.2		 3gczA-5ikmA:
54.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HCN_A_CHDA3_0
(FERROCHELATASE,
MITOCHONDRIAL)		 4a29 ENGINEERED
RETRO-ALDOL ENZYME
RA95.0
(synthetic
construct) 		4 / 7 LEU A 159
ARG A 182
SER A  81
GLY A 212
 None
MLT  A 300 ( 3.9A)
None
MLT  A 300 (-2.8A)
 1.09A 3hcnA-4a29A:
undetectable		 3hcnA-4a29A:
22.99
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3HKU_A_TORA300_1
(CARBONIC ANHYDRASE 2)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		6 / 12 GLN A 121
HIS A 123
HIS A 125
VAL A 144
LEU A 214
THR A 215
 MLT  A   3 (-3.9A)
ZN  A   1 ( 3.2A)
ZN  A   1 (-3.3A)
None
MLT  A   3 ( 4.2A)
MLT  A   3 ( 4.3A)
 1.44A 3hkuA-3q31A:
24.6		 3hkuA-3q31A:
30.69
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3HKU_A_TORA300_1
(CARBONIC ANHYDRASE 2)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		8 / 12 GLN A 121
HIS A 123
HIS A 125
VAL A 144
VAL A 154
LEU A 214
THR A 216
TRP A 225
 MLT  A   3 (-3.9A)
ZN  A   1 ( 3.2A)
ZN  A   1 (-3.3A)
None
MLT  A   3 (-4.6A)
MLT  A   3 ( 4.2A)
MLT  A   3 (-2.8A)
MLT  A   3 (-4.9A)
 0.44A 3hkuA-3q31A:
24.6		 3hkuA-3q31A:
30.69
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3HKU_A_TORA300_1
(CARBONIC ANHYDRASE 2)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		5 / 12 HIS A 142
HIS A 125
VAL A 154
LEU A 214
THR A 216
 ZN  A   1 ( 3.2A)
ZN  A   1 (-3.3A)
MLT  A   3 (-4.6A)
MLT  A   3 ( 4.2A)
MLT  A   3 (-2.8A)
 1.28A 3hkuA-3q31A:
24.6		 3hkuA-3q31A:
30.69
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3HKU_A_TORA300_2
(CARBONIC ANHYDRASE 2)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		3 / 3 GLU A 129
HIS A 142
THR A 215
 ZN  A   1 ( 4.7A)
ZN  A   1 ( 3.2A)
MLT  A   3 ( 4.3A)
 0.20A 3hkuA-3q31A:
24.6		 3hkuA-3q31A:
30.69
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3HS4_A_AZMA701_1
(CARBONIC ANHYDRASE 2)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		6 / 11 GLN A 102
HIS A 123
HIS A 125
HIS A 142
THR A 215
THR A 216
 None
ZN  A   1 ( 3.2A)
ZN  A   1 (-3.3A)
ZN  A   1 ( 3.2A)
MLT  A   3 ( 4.3A)
MLT  A   3 (-2.8A)
 1.04A 3hs4A-3q31A:
24.7		 3hs4A-3q31A:
30.69
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3HS4_A_AZMA701_1
(CARBONIC ANHYDRASE 2)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		5 / 11 GLN A 102
HIS A 125
VAL A 144
THR A 215
THR A 216
 None
ZN  A   1 (-3.3A)
None
MLT  A   3 ( 4.3A)
MLT  A   3 (-2.8A)
 1.11A 3hs4A-3q31A:
24.7		 3hs4A-3q31A:
30.69
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3HS4_A_AZMA701_1
(CARBONIC ANHYDRASE 2)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		10 / 11 GLN A 121
HIS A 123
HIS A 125
HIS A 142
VAL A 144
VAL A 154
LEU A 214
THR A 215
THR A 216
TRP A 225
 MLT  A   3 (-3.9A)
ZN  A   1 ( 3.2A)
ZN  A   1 (-3.3A)
ZN  A   1 ( 3.2A)
None
MLT  A   3 (-4.6A)
MLT  A   3 ( 4.2A)
MLT  A   3 ( 4.3A)
MLT  A   3 (-2.8A)
MLT  A   3 (-4.9A)
 0.37A 3hs4A-3q31A:
24.7		 3hs4A-3q31A:
30.69
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3HS4_A_AZMA701_1
(CARBONIC ANHYDRASE 2)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		6 / 11 GLN A 121
HIS A 123
HIS A 125
VAL A 144
LEU A 214
THR A 215
 MLT  A   3 (-3.9A)
ZN  A   1 ( 3.2A)
ZN  A   1 (-3.3A)
None
MLT  A   3 ( 4.2A)
MLT  A   3 ( 4.3A)
 1.42A 3hs4A-3q31A:
24.7		 3hs4A-3q31A:
30.69
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3HS4_A_AZMA701_1
(CARBONIC ANHYDRASE 2)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		6 / 11 HIS A 123
HIS A 142
VAL A 154
LEU A 214
THR A 216
TRP A 225
 ZN  A   1 ( 3.2A)
ZN  A   1 ( 3.2A)
MLT  A   3 (-4.6A)
MLT  A   3 ( 4.2A)
MLT  A   3 (-2.8A)
MLT  A   3 (-4.9A)
 1.49A 3hs4A-3q31A:
24.7		 3hs4A-3q31A:
30.69
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3HS4_A_AZMA701_1
(CARBONIC ANHYDRASE 2)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		5 / 11 HIS A 142
HIS A 125
VAL A 154
LEU A 214
THR A 216
 ZN  A   1 ( 3.2A)
ZN  A   1 (-3.3A)
MLT  A   3 (-4.6A)
MLT  A   3 ( 4.2A)
MLT  A   3 (-2.8A)
 1.31A 3hs4A-3q31A:
24.7		 3hs4A-3q31A:
30.69
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3IAI_A_AZMA263_1
(CARBONIC ANHYDRASE 9)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		7 / 11 GLN A 102
HIS A 123
HIS A 125
GLU A 129
HIS A 142
THR A 215
THR A 216
 None
ZN  A   1 ( 3.2A)
ZN  A   1 (-3.3A)
ZN  A   1 ( 4.7A)
ZN  A   1 ( 3.2A)
MLT  A   3 ( 4.3A)
MLT  A   3 (-2.8A)
 1.07A 3iaiA-3q31A:
24.6		 3iaiA-3q31A:
30.66
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3IAI_A_AZMA263_1
(CARBONIC ANHYDRASE 9)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		6 / 11 GLN A 121
HIS A 123
GLU A 140
HIS A 142
VAL A 144
TRP A 225
 MLT  A   3 (-3.9A)
ZN  A   1 ( 3.2A)
None
ZN  A   1 ( 3.2A)
None
MLT  A   3 (-4.9A)
 1.48A 3iaiA-3q31A:
24.6		 3iaiA-3q31A:
30.66
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3IAI_A_AZMA263_1
(CARBONIC ANHYDRASE 9)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		5 / 11 GLN A 121
HIS A 123
GLU A 140
VAL A 144
THR A 215
 MLT  A   3 (-3.9A)
ZN  A   1 ( 3.2A)
None
None
MLT  A   3 ( 4.3A)
 1.15A 3iaiA-3q31A:
24.6		 3iaiA-3q31A:
30.66
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3IAI_A_AZMA263_1
(CARBONIC ANHYDRASE 9)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		10 / 11 GLN A 121
HIS A 123
HIS A 125
GLU A 129
HIS A 142
VAL A 144
LEU A 214
THR A 215
THR A 216
TRP A 225
 MLT  A   3 (-3.9A)
ZN  A   1 ( 3.2A)
ZN  A   1 (-3.3A)
ZN  A   1 ( 4.7A)
ZN  A   1 ( 3.2A)
None
MLT  A   3 ( 4.2A)
MLT  A   3 ( 4.3A)
MLT  A   3 (-2.8A)
MLT  A   3 (-4.9A)
 0.36A 3iaiA-3q31A:
24.6		 3iaiA-3q31A:
30.66
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3IAI_A_AZMA263_1
(CARBONIC ANHYDRASE 9)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		6 / 11 HIS A 125
GLU A 129
VAL A 154
LEU A 214
THR A 215
THR A 216
 ZN  A   1 (-3.3A)
ZN  A   1 ( 4.7A)
MLT  A   3 (-4.6A)
MLT  A   3 ( 4.2A)
MLT  A   3 ( 4.3A)
MLT  A   3 (-2.8A)
 0.90A 3iaiA-3q31A:
24.6		 3iaiA-3q31A:
30.66
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3IAI_B_AZMB263_1
(CARBONIC ANHYDRASE 9)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		7 / 11 GLN A 102
HIS A 123
HIS A 125
GLU A 129
HIS A 142
THR A 215
THR A 216
 None
ZN  A   1 ( 3.2A)
ZN  A   1 (-3.3A)
ZN  A   1 ( 4.7A)
ZN  A   1 ( 3.2A)
MLT  A   3 ( 4.3A)
MLT  A   3 (-2.8A)
 1.06A 3iaiB-3q31A:
24.8		 3iaiB-3q31A:
30.66
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3IAI_B_AZMB263_1
(CARBONIC ANHYDRASE 9)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		6 / 11 GLN A 121
HIS A 123
GLU A 140
HIS A 142
VAL A 144
TRP A 225
 MLT  A   3 (-3.9A)
ZN  A   1 ( 3.2A)
None
ZN  A   1 ( 3.2A)
None
MLT  A   3 (-4.9A)
 1.48A 3iaiB-3q31A:
24.8		 3iaiB-3q31A:
30.66
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3IAI_B_AZMB263_1
(CARBONIC ANHYDRASE 9)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		5 / 11 GLN A 121
HIS A 123
GLU A 140
VAL A 144
THR A 215
 MLT  A   3 (-3.9A)
ZN  A   1 ( 3.2A)
None
None
MLT  A   3 ( 4.3A)
 1.16A 3iaiB-3q31A:
24.8		 3iaiB-3q31A:
30.66
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3IAI_B_AZMB263_1
(CARBONIC ANHYDRASE 9)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		10 / 11 GLN A 121
HIS A 123
HIS A 125
GLU A 129
HIS A 142
VAL A 144
LEU A 214
THR A 215
THR A 216
TRP A 225
 MLT  A   3 (-3.9A)
ZN  A   1 ( 3.2A)
ZN  A   1 (-3.3A)
ZN  A   1 ( 4.7A)
ZN  A   1 ( 3.2A)
None
MLT  A   3 ( 4.2A)
MLT  A   3 ( 4.3A)
MLT  A   3 (-2.8A)
MLT  A   3 (-4.9A)
 0.37A 3iaiB-3q31A:
24.8		 3iaiB-3q31A:
30.66
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3IAI_B_AZMB263_1
(CARBONIC ANHYDRASE 9)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		6 / 11 HIS A 125
GLU A 129
VAL A 154
LEU A 214
THR A 215
THR A 216
 ZN  A   1 (-3.3A)
ZN  A   1 ( 4.7A)
MLT  A   3 (-4.6A)
MLT  A   3 ( 4.2A)
MLT  A   3 ( 4.3A)
MLT  A   3 (-2.8A)
 0.89A 3iaiB-3q31A:
24.8		 3iaiB-3q31A:
30.66
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3IAI_C_AZMC263_1
(CARBONIC ANHYDRASE 9)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		7 / 11 GLN A 102
HIS A 123
HIS A 125
GLU A 129
HIS A 142
THR A 215
THR A 216
 None
ZN  A   1 ( 3.2A)
ZN  A   1 (-3.3A)
ZN  A   1 ( 4.7A)
ZN  A   1 ( 3.2A)
MLT  A   3 ( 4.3A)
MLT  A   3 (-2.8A)
 1.07A 3iaiC-3q31A:
24.8		 3iaiC-3q31A:
30.66
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3IAI_C_AZMC263_1
(CARBONIC ANHYDRASE 9)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		6 / 11 GLN A 121
HIS A 123
GLU A 140
HIS A 142
VAL A 144
TRP A 225
 MLT  A   3 (-3.9A)
ZN  A   1 ( 3.2A)
None
ZN  A   1 ( 3.2A)
None
MLT  A   3 (-4.9A)
 1.49A 3iaiC-3q31A:
24.8		 3iaiC-3q31A:
30.66
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3IAI_C_AZMC263_1
(CARBONIC ANHYDRASE 9)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		5 / 11 GLN A 121
HIS A 123
GLU A 140
VAL A 144
THR A 215
 MLT  A   3 (-3.9A)
ZN  A   1 ( 3.2A)
None
None
MLT  A   3 ( 4.3A)
 1.15A 3iaiC-3q31A:
24.8		 3iaiC-3q31A:
30.66
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3IAI_C_AZMC263_1
(CARBONIC ANHYDRASE 9)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		10 / 11 GLN A 121
HIS A 123
HIS A 125
GLU A 129
HIS A 142
VAL A 144
LEU A 214
THR A 215
THR A 216
TRP A 225
 MLT  A   3 (-3.9A)
ZN  A   1 ( 3.2A)
ZN  A   1 (-3.3A)
ZN  A   1 ( 4.7A)
ZN  A   1 ( 3.2A)
None
MLT  A   3 ( 4.2A)
MLT  A   3 ( 4.3A)
MLT  A   3 (-2.8A)
MLT  A   3 (-4.9A)
 0.34A 3iaiC-3q31A:
24.8		 3iaiC-3q31A:
30.66
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3IAI_C_AZMC263_1
(CARBONIC ANHYDRASE 9)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		6 / 11 HIS A 125
GLU A 129
VAL A 154
LEU A 214
THR A 215
THR A 216
 ZN  A   1 (-3.3A)
ZN  A   1 ( 4.7A)
MLT  A   3 (-4.6A)
MLT  A   3 ( 4.2A)
MLT  A   3 ( 4.3A)
MLT  A   3 (-2.8A)
 0.89A 3iaiC-3q31A:
24.8		 3iaiC-3q31A:
30.66
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3IAI_D_AZMD263_1
(CARBONIC ANHYDRASE 9)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		7 / 11 GLN A 102
HIS A 123
HIS A 125
GLU A 129
HIS A 142
THR A 215
THR A 216
 None
ZN  A   1 ( 3.2A)
ZN  A   1 (-3.3A)
ZN  A   1 ( 4.7A)
ZN  A   1 ( 3.2A)
MLT  A   3 ( 4.3A)
MLT  A   3 (-2.8A)
 1.07A 3iaiD-3q31A:
24.8		 3iaiD-3q31A:
30.66
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3IAI_D_AZMD263_1
(CARBONIC ANHYDRASE 9)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		6 / 11 GLN A 121
HIS A 123
GLU A 140
HIS A 142
VAL A 144
TRP A 225
 MLT  A   3 (-3.9A)
ZN  A   1 ( 3.2A)
None
ZN  A   1 ( 3.2A)
None
MLT  A   3 (-4.9A)
 1.48A 3iaiD-3q31A:
24.8		 3iaiD-3q31A:
30.66
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3IAI_D_AZMD263_1
(CARBONIC ANHYDRASE 9)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		5 / 11 GLN A 121
HIS A 123
GLU A 140
VAL A 144
THR A 215
 MLT  A   3 (-3.9A)
ZN  A   1 ( 3.2A)
None
None
MLT  A   3 ( 4.3A)
 1.15A 3iaiD-3q31A:
24.8		 3iaiD-3q31A:
30.66
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3IAI_D_AZMD263_1
(CARBONIC ANHYDRASE 9)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		10 / 11 GLN A 121
HIS A 123
HIS A 125
GLU A 129
HIS A 142
VAL A 144
LEU A 214
THR A 215
THR A 216
TRP A 225
 MLT  A   3 (-3.9A)
ZN  A   1 ( 3.2A)
ZN  A   1 (-3.3A)
ZN  A   1 ( 4.7A)
ZN  A   1 ( 3.2A)
None
MLT  A   3 ( 4.2A)
MLT  A   3 ( 4.3A)
MLT  A   3 (-2.8A)
MLT  A   3 (-4.9A)
 0.37A 3iaiD-3q31A:
24.8		 3iaiD-3q31A:
30.66
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3IAI_D_AZMD263_1
(CARBONIC ANHYDRASE 9)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		6 / 11 GLN A 121
HIS A 123
HIS A 125
VAL A 144
LEU A 214
THR A 215
 MLT  A   3 (-3.9A)
ZN  A   1 ( 3.2A)
ZN  A   1 (-3.3A)
None
MLT  A   3 ( 4.2A)
MLT  A   3 ( 4.3A)
 1.44A 3iaiD-3q31A:
24.8		 3iaiD-3q31A:
30.66
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3IAI_D_AZMD263_1
(CARBONIC ANHYDRASE 9)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		6 / 11 HIS A 125
GLU A 129
VAL A 154
LEU A 214
THR A 215
THR A 216
 ZN  A   1 (-3.3A)
ZN  A   1 ( 4.7A)
MLT  A   3 (-4.6A)
MLT  A   3 ( 4.2A)
MLT  A   3 ( 4.3A)
MLT  A   3 (-2.8A)
 0.88A 3iaiD-3q31A:
24.8		 3iaiD-3q31A:
30.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K13_A_THHA642_1
(5-METHYLTETRAHYDROFO
LATE-HOMOCYSTEINE
METHYLTRANSFERASE)		 4pfr TRAP DICARBOXYLATE
TRANSPORTER, DCTP
SUBUNIT
(Rhodobacter
sphaeroides) 		3 / 3 ASN A  65
ASP A  32
ARG A 166
 None
None
MLT  A 401 (-3.1A)
 0.56A 3k13A-4pfrA:
undetectable		 3k13A-4pfrA:
23.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K13_C_THHC643_1
(5-METHYLTETRAHYDROFO
LATE-HOMOCYSTEINE
METHYLTRANSFERASE)		 2fgq OUTER MEMBRANE PORIN
PROTEIN 32
(Delftia
acidovorans) 		3 / 3 ASN X  13
ASP X  64
ARG X 133
 None
CA  X 501 (-3.4A)
MLT  X 700 (-3.1A)
 0.90A 3k13C-2fgqX:
undetectable		 3k13C-2fgqX:
22.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEC_B_HAEB271_1
(COLLAGENASE 3)		 5a2r ANGIOTENSIN-CONVERTI
NG ENZYME
(Drosophila
melanogaster) 		3 / 3 HIS A 367
GLU A 368
HIS A 371
 ZN  A1616 (-3.2A)
MLT  A1615 (-4.3A)
ZN  A1616 (-3.3A)
 0.16A 3kecB-5a2rA:
3.5		 3kecB-5a2rA:
14.26
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3KWA_A_SPMA300_1
(CARBONIC ANHYDRASE 2)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		5 / 11 GLN A 102
HIS A 123
HIS A 142
THR A 215
THR A 216
 None
ZN  A   1 ( 3.2A)
ZN  A   1 ( 3.2A)
MLT  A   3 ( 4.3A)
MLT  A   3 (-2.8A)
 1.15A 3kwaA-3q31A:
24.3		 3kwaA-3q31A:
30.69
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3KWA_A_SPMA300_1
(CARBONIC ANHYDRASE 2)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		10 / 11 GLN A 121
HIS A 123
HIS A 142
VAL A 144
VAL A 154
LEU A 214
THR A 215
THR A 216
PRO A 218
TRP A 225
 MLT  A   3 (-3.9A)
ZN  A   1 ( 3.2A)
ZN  A   1 ( 3.2A)
None
MLT  A   3 (-4.6A)
MLT  A   3 ( 4.2A)
MLT  A   3 ( 4.3A)
MLT  A   3 (-2.8A)
None
MLT  A   3 (-4.9A)
 0.44A 3kwaA-3q31A:
24.3		 3kwaA-3q31A:
30.69
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3KWA_A_SPMA300_1
(CARBONIC ANHYDRASE 2)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		7 / 11 HIS A 123
HIS A 142
VAL A 154
LEU A 214
THR A 215
PRO A 217
TRP A 225
 ZN  A   1 ( 3.2A)
ZN  A   1 ( 3.2A)
MLT  A   3 (-4.6A)
MLT  A   3 ( 4.2A)
MLT  A   3 ( 4.3A)
None
MLT  A   3 (-4.9A)
 1.34A 3kwaA-3q31A:
24.3		 3kwaA-3q31A:
30.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LXE_A_TORA262_1
(CARBONIC ANHYDRASE 1)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		7 / 12 GLN A 121
HIS A 123
HIS A 125
VAL A 154
LEU A 214
THR A 215
TRP A 225
 MLT  A   3 (-3.9A)
ZN  A   1 ( 3.2A)
ZN  A   1 (-3.3A)
MLT  A   3 (-4.6A)
MLT  A   3 ( 4.2A)
MLT  A   3 ( 4.3A)
MLT  A   3 (-4.9A)
 0.55A 3lxeA-3q31A:
23.7		 3lxeA-3q31A:
28.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LXE_B_TORB262_1
(CARBONIC ANHYDRASE 1)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		7 / 12 GLN A 121
HIS A 123
HIS A 125
VAL A 154
LEU A 214
THR A 215
TRP A 225
 MLT  A   3 (-3.9A)
ZN  A   1 ( 3.2A)
ZN  A   1 (-3.3A)
MLT  A   3 (-4.6A)
MLT  A   3 ( 4.2A)
MLT  A   3 ( 4.3A)
MLT  A   3 (-4.9A)
 0.55A 3lxeB-3q31A:
23.8		 3lxeB-3q31A:
28.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MDZ_A_EZLA264_1
(CARBONIC ANHYDRASE 7)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		10 / 11 HIS A 123
HIS A 125
GLU A 129
HIS A 142
VAL A 144
LEU A 214
THR A 215
THR A 216
PRO A 218
TRP A 225
 ZN  A   1 ( 3.2A)
ZN  A   1 (-3.3A)
ZN  A   1 ( 4.7A)
ZN  A   1 ( 3.2A)
None
MLT  A   3 ( 4.2A)
MLT  A   3 ( 4.3A)
MLT  A   3 (-2.8A)
None
MLT  A   3 (-4.9A)
 0.38A 3mdzA-3q31A:
24.2		 3mdzA-3q31A:
29.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MDZ_A_EZLA264_1
(CARBONIC ANHYDRASE 7)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		7 / 11 HIS A 123
HIS A 142
LEU A 214
THR A 215
THR A 216
PRO A 218
TRP A 225
 ZN  A   1 ( 3.2A)
ZN  A   1 ( 3.2A)
MLT  A   3 ( 4.2A)
MLT  A   3 ( 4.3A)
MLT  A   3 (-2.8A)
None
MLT  A   3 (-4.9A)
 1.40A 3mdzA-3q31A:
24.2		 3mdzA-3q31A:
29.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MDZ_A_EZLA264_1
(CARBONIC ANHYDRASE 7)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		7 / 11 HIS A 123
HIS A 142
VAL A 144
LEU A 214
THR A 215
PRO A 217
TRP A 225
 ZN  A   1 ( 3.2A)
ZN  A   1 ( 3.2A)
None
MLT  A   3 ( 4.2A)
MLT  A   3 ( 4.3A)
None
MLT  A   3 (-4.9A)
 1.42A 3mdzA-3q31A:
24.2		 3mdzA-3q31A:
29.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MDZ_A_EZLA264_1
(CARBONIC ANHYDRASE 7)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		7 / 11 HIS A 125
GLU A 129
VAL A 154
LEU A 214
THR A 215
THR A 216
PRO A 218
 ZN  A   1 (-3.3A)
ZN  A   1 ( 4.7A)
MLT  A   3 (-4.6A)
MLT  A   3 ( 4.2A)
MLT  A   3 ( 4.3A)
MLT  A   3 (-2.8A)
None
 0.99A 3mdzA-3q31A:
24.2		 3mdzA-3q31A:
29.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MDZ_A_EZLA264_1
(CARBONIC ANHYDRASE 7)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		6 / 11 HIS A 142
HIS A 125
VAL A 154
LEU A 214
THR A 215
THR A 216
 ZN  A   1 ( 3.2A)
ZN  A   1 (-3.3A)
MLT  A   3 (-4.6A)
MLT  A   3 ( 4.2A)
MLT  A   3 ( 4.3A)
MLT  A   3 (-2.8A)
 1.31A 3mdzA-3q31A:
24.2		 3mdzA-3q31A:
29.63
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3ML5_A_AZMA264_1
(CARBONIC ANHYDRASE 7)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		6 / 11 GLN A 102
HIS A 123
HIS A 125
HIS A 142
THR A 215
THR A 216
 None
ZN  A   1 ( 3.2A)
ZN  A   1 (-3.3A)
ZN  A   1 ( 3.2A)
MLT  A   3 ( 4.3A)
MLT  A   3 (-2.8A)
 1.06A 3ml5A-3q31A:
24.5		 3ml5A-3q31A:
30.25
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3ML5_A_AZMA264_1
(CARBONIC ANHYDRASE 7)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		5 / 11 GLN A 102
HIS A 125
VAL A 144
THR A 215
THR A 216
 None
ZN  A   1 (-3.3A)
None
MLT  A   3 ( 4.3A)
MLT  A   3 (-2.8A)
 1.12A 3ml5A-3q31A:
24.5		 3ml5A-3q31A:
30.25
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3ML5_A_AZMA264_1
(CARBONIC ANHYDRASE 7)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		10 / 11 GLN A 121
HIS A 123
HIS A 125
HIS A 142
VAL A 144
VAL A 154
LEU A 214
THR A 215
THR A 216
TRP A 225
 MLT  A   3 (-3.9A)
ZN  A   1 ( 3.2A)
ZN  A   1 (-3.3A)
ZN  A   1 ( 3.2A)
None
MLT  A   3 (-4.6A)
MLT  A   3 ( 4.2A)
MLT  A   3 ( 4.3A)
MLT  A   3 (-2.8A)
MLT  A   3 (-4.9A)
 0.34A 3ml5A-3q31A:
24.5		 3ml5A-3q31A:
30.25
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3ML5_A_AZMA264_1
(CARBONIC ANHYDRASE 7)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		7 / 11 HIS A 123
HIS A 142
VAL A 154
LEU A 214
THR A 215
THR A 216
TRP A 225
 ZN  A   1 ( 3.2A)
ZN  A   1 ( 3.2A)
MLT  A   3 (-4.6A)
MLT  A   3 ( 4.2A)
MLT  A   3 ( 4.3A)
MLT  A   3 (-2.8A)
MLT  A   3 (-4.9A)
 1.44A 3ml5A-3q31A:
24.5		 3ml5A-3q31A:
30.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N8X_A_NIMA701_1
(PROSTAGLANDIN G/H
SYNTHASE 1)		 5kvu ISOCITRATE
DEHYDROGENASE
(Mycobacterium
tuberculosis) 		5 / 12 ARG A 147
TRP A 604
GLY A 584
ALA A 585
SER A 565
 MLT  A 802 ( 4.6A)
NAP  A 801 (-3.2A)
None
None
None
 1.24A 3n8xA-5kvuA:
1.6		 3n8xA-5kvuA:
20.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OU7_B_SAMB300_1
(SAM-DEPENDENT
METHYLTRANSFERASE)		 5a2r ANGIOTENSIN-CONVERTI
NG ENZYME
(Drosophila
melanogaster) 		3 / 3 TYR A 507
ASP A 399
ASP A 437
 MLT  A1615 (-4.0A)
None
None
 0.99A 3ou7B-5a2rA:
undetectable		 3ou7B-5a2rA:
18.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P2K_C_SAMC6735_1
(16S RRNA METHYLASE)		 5kvu ISOCITRATE
DEHYDROGENASE
(Mycobacterium
tuberculosis) 		4 / 5 ASN A 137
GLU A 498
THR A 383
SER A 134
 NAP  A 801 ( 3.6A)
None
None
MLT  A 802 (-2.6A)
 1.40A 3p2kC-5kvuA:
undetectable		 3p2kC-5kvuA:
15.15
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3P97_A_SAMA263_0
(NON-STRUCTURAL
PROTEIN 5)		 5ikm NS5 METHYL
TRANSFERASE
(Dengue
virus) 		12 / 12 GLY A  58
GLY A  81
GLY A  83
GLY A  86
TRP A  87
THR A 104
LYS A 105
HIS A 110
ASP A 131
VAL A 132
ASP A 146
ILE A 147
 SAM  A 311 (-3.3A)
SAM  A 311 (-3.2A)
SAM  A 311 (-3.3A)
SAM  A 311 (-3.3A)
SAM  A 311 (-3.5A)
SAM  A 311 (-4.5A)
MLT  A 313 ( 3.0A)
SAM  A 311 (-4.1A)
MLT  A 313 ( 2.6A)
SAM  A 311 (-3.7A)
SAM  A 311 (-3.8A)
SAM  A 311 ( 4.3A)
 0.61A 3p97A-5ikmA:
42.7		 3p97A-5ikmA:
81.65
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3P97_C_SAMC263_0
(NON-STRUCTURAL
PROTEIN 5)		 5ikm NS5 METHYL
TRANSFERASE
(Dengue
virus) 		10 / 12 GLY A  58
GLY A  81
GLY A  83
GLY A  86
THR A 104
LYS A 105
GLU A 111
ASP A 131
VAL A 132
ILE A 147
 SAM  A 311 (-3.3A)
SAM  A 311 (-3.2A)
SAM  A 311 (-3.3A)
SAM  A 311 (-3.3A)
SAM  A 311 (-4.5A)
MLT  A 313 ( 3.0A)
None
MLT  A 313 ( 2.6A)
SAM  A 311 (-3.7A)
SAM  A 311 ( 4.3A)
 0.68A 3p97C-5ikmA:
42.5		 3p97C-5ikmA:
81.65
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3P97_C_SAMC263_0
(NON-STRUCTURAL
PROTEIN 5)		 5ikm NS5 METHYL
TRANSFERASE
(Dengue
virus) 		11 / 12 GLY A  58
GLY A  81
GLY A  83
GLY A  86
TRP A  87
THR A 104
LYS A 105
ASP A 131
VAL A 132
ASP A 146
ILE A 147
 SAM  A 311 (-3.3A)
SAM  A 311 (-3.2A)
SAM  A 311 (-3.3A)
SAM  A 311 (-3.3A)
SAM  A 311 (-3.5A)
SAM  A 311 (-4.5A)
MLT  A 313 ( 3.0A)
MLT  A 313 ( 2.6A)
SAM  A 311 (-3.7A)
SAM  A 311 (-3.8A)
SAM  A 311 ( 4.3A)
 0.43A 3p97C-5ikmA:
42.5		 3p97C-5ikmA:
81.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QEL_D_QELD2_1
(NMDA GLUTAMATE
RECEPTOR SUBUNIT
GLUTAMATE [NMDA]
RECEPTOR SUBUNIT
EPSILON-2)		 2fgq OUTER MEMBRANE PORIN
PROTEIN 32
(Delftia
acidovorans) 		4 / 5 TYR X 104
THR X 102
PHE X 115
LEU X 106
 None
MLT  X 700 (-2.9A)
None
None
 1.34A 3qelC-2fgqX:
undetectable		 3qelC-2fgqX:
21.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S8P_A_SAMA500_1
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SUV420H1)		 5a2r ANGIOTENSIN-CONVERTI
NG ENZYME
(Drosophila
melanogaster) 		3 / 3 HIS A 497
SER A 510
GLU A 395
 MLT  A1615 (-4.0A)
None
ZN  A1616 (-2.4A)
 0.80A 3s8pA-5a2rA:
undetectable		 3s8pA-5a2rA:
18.24
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3UY4_A_PAUA302_0
(PANTOTHENATE
SYNTHETASE)		 3uk2 PANTOTHENATE
SYNTHETASE
(Burkholderia
thailandensis) 		7 / 8 GLN A  57
ARG A 118
VAL A 125
VAL A 128
ASP A 147
GLN A 150
ARG A 184
 EDO  A 285 ( 3.0A)
MLT  A 284 (-3.3A)
EDO  A 285 (-4.0A)
EDO  A 285 (-4.9A)
MLT  A 284 ( 3.5A)
MLT  A 284 ( 2.8A)
MLT  A 284 (-3.1A)
 0.24A 3uy4A-3uk2A:
38.3		 3uy4A-3uk2A:
38.64
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3UY4_A_PAUA302_0
(PANTOTHENATE
SYNTHETASE)		 3uk2 PANTOTHENATE
SYNTHETASE
(Burkholderia
thailandensis) 		5 / 8 GLN A  57
ARG A 118
VAL A 125
VAL A 129
ARG A 184
 EDO  A 285 ( 3.0A)
MLT  A 284 (-3.3A)
EDO  A 285 (-4.0A)
None
MLT  A 284 (-3.1A)
 1.40A 3uy4A-3uk2A:
38.3		 3uy4A-3uk2A:
38.64
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3V2J_A_AZMA302_1
(CARBONIC ANHYDRASE 2)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		6 / 11 GLN A 102
HIS A 123
HIS A 125
HIS A 142
THR A 215
THR A 216
 None
ZN  A   1 ( 3.2A)
ZN  A   1 (-3.3A)
ZN  A   1 ( 3.2A)
MLT  A   3 ( 4.3A)
MLT  A   3 (-2.8A)
 1.08A 3v2jA-3q31A:
24.4		 3v2jA-3q31A:
30.69
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3V2J_A_AZMA302_1
(CARBONIC ANHYDRASE 2)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		5 / 11 GLN A 102
HIS A 125
VAL A 144
THR A 215
THR A 216
 None
ZN  A   1 (-3.3A)
None
MLT  A   3 ( 4.3A)
MLT  A   3 (-2.8A)
 1.14A 3v2jA-3q31A:
24.4		 3v2jA-3q31A:
30.69
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3V2J_A_AZMA302_1
(CARBONIC ANHYDRASE 2)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		10 / 11 GLN A 121
HIS A 123
HIS A 125
HIS A 142
VAL A 144
VAL A 154
LEU A 214
THR A 215
THR A 216
TRP A 225
 MLT  A   3 (-3.9A)
ZN  A   1 ( 3.2A)
ZN  A   1 (-3.3A)
ZN  A   1 ( 3.2A)
None
MLT  A   3 (-4.6A)
MLT  A   3 ( 4.2A)
MLT  A   3 ( 4.3A)
MLT  A   3 (-2.8A)
MLT  A   3 (-4.9A)
 0.35A 3v2jA-3q31A:
24.4		 3v2jA-3q31A:
30.69
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3V2J_A_AZMA302_1
(CARBONIC ANHYDRASE 2)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		6 / 11 GLN A 121
HIS A 123
HIS A 125
VAL A 144
LEU A 214
THR A 215
 MLT  A   3 (-3.9A)
ZN  A   1 ( 3.2A)
ZN  A   1 (-3.3A)
None
MLT  A   3 ( 4.2A)
MLT  A   3 ( 4.3A)
 1.47A 3v2jA-3q31A:
24.4		 3v2jA-3q31A:
30.69
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3V2J_A_AZMA302_1
(CARBONIC ANHYDRASE 2)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		7 / 11 HIS A 123
HIS A 142
VAL A 154
LEU A 214
THR A 215
THR A 216
TRP A 225
 ZN  A   1 ( 3.2A)
ZN  A   1 ( 3.2A)
MLT  A   3 (-4.6A)
MLT  A   3 ( 4.2A)
MLT  A   3 ( 4.3A)
MLT  A   3 (-2.8A)
MLT  A   3 (-4.9A)
 1.44A 3v2jA-3q31A:
24.4		 3v2jA-3q31A:
30.69
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3V2J_A_AZMA302_1
(CARBONIC ANHYDRASE 2)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		5 / 11 HIS A 142
HIS A 125
VAL A 154
LEU A 214
THR A 216
 ZN  A   1 ( 3.2A)
ZN  A   1 (-3.3A)
MLT  A   3 (-4.6A)
MLT  A   3 ( 4.2A)
MLT  A   3 (-2.8A)
 1.33A 3v2jA-3q31A:
24.4		 3v2jA-3q31A:
30.69
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3V2M_A_AZMA303_1
(CARBONIC ANHYDRASE 2)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		5 / 10 GLN A 102
HIS A 123
HIS A 125
THR A 215
THR A 216
 None
ZN  A   1 ( 3.2A)
ZN  A   1 (-3.3A)
MLT  A   3 ( 4.3A)
MLT  A   3 (-2.8A)
 1.11A 3v2mA-3q31A:
24.6		 3v2mA-3q31A:
30.69
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3V2M_A_AZMA303_1
(CARBONIC ANHYDRASE 2)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		9 / 10 GLN A 121
HIS A 123
HIS A 125
HIS A 142
VAL A 144
LEU A 214
THR A 215
THR A 216
TRP A 225
 MLT  A   3 (-3.9A)
ZN  A   1 ( 3.2A)
ZN  A   1 (-3.3A)
ZN  A   1 ( 3.2A)
None
MLT  A   3 ( 4.2A)
MLT  A   3 ( 4.3A)
MLT  A   3 (-2.8A)
MLT  A   3 (-4.9A)
 0.28A 3v2mA-3q31A:
24.6		 3v2mA-3q31A:
30.69
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3V2M_A_AZMA303_1
(CARBONIC ANHYDRASE 2)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		5 / 10 HIS A 125
VAL A 154
LEU A 214
THR A 215
THR A 216
 ZN  A   1 (-3.3A)
MLT  A   3 (-4.6A)
MLT  A   3 ( 4.2A)
MLT  A   3 ( 4.3A)
MLT  A   3 (-2.8A)
 0.89A 3v2mA-3q31A:
24.6		 3v2mA-3q31A:
30.69
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3V2M_A_AZMA303_1
(CARBONIC ANHYDRASE 2)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		5 / 10 HIS A 142
HIS A 125
VAL A 154
LEU A 214
THR A 215
 ZN  A   1 ( 3.2A)
ZN  A   1 (-3.3A)
MLT  A   3 (-4.6A)
MLT  A   3 ( 4.2A)
MLT  A   3 ( 4.3A)
 1.33A 3v2mA-3q31A:
24.6		 3v2mA-3q31A:
30.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W6H_A_AZMA303_1
(CARBONIC ANHYDRASE 1)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		5 / 8 GLN A 102
HIS A 123
HIS A 125
HIS A 142
THR A 215
 None
ZN  A   1 ( 3.2A)
ZN  A   1 (-3.3A)
ZN  A   1 ( 3.2A)
MLT  A   3 ( 4.3A)
 0.82A 3w6hA-3q31A:
23.6		 3w6hA-3q31A:
28.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W6H_A_AZMA303_1
(CARBONIC ANHYDRASE 1)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		7 / 8 GLN A 121
HIS A 123
HIS A 125
HIS A 142
LEU A 214
THR A 215
TRP A 225
 MLT  A   3 (-3.9A)
ZN  A   1 ( 3.2A)
ZN  A   1 (-3.3A)
ZN  A   1 ( 3.2A)
MLT  A   3 ( 4.2A)
MLT  A   3 ( 4.3A)
MLT  A   3 (-4.9A)
 0.44A 3w6hA-3q31A:
23.6		 3w6hA-3q31A:
28.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W6H_A_AZMA303_1
(CARBONIC ANHYDRASE 1)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		5 / 8 HIS A 123
HIS A 142
LEU A 214
THR A 215
TRP A 225
 ZN  A   1 ( 3.2A)
ZN  A   1 ( 3.2A)
MLT  A   3 ( 4.2A)
MLT  A   3 ( 4.3A)
MLT  A   3 (-4.9A)
 1.50A 3w6hA-3q31A:
23.6		 3w6hA-3q31A:
28.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W6H_B_AZMB303_1
(CARBONIC ANHYDRASE 1)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		6 / 9 GLN A 102
HIS A 123
HIS A 125
GLU A 129
HIS A 142
THR A 215
 None
ZN  A   1 ( 3.2A)
ZN  A   1 (-3.3A)
ZN  A   1 ( 4.7A)
ZN  A   1 ( 3.2A)
MLT  A   3 ( 4.3A)
 0.80A 3w6hB-3q31A:
23.5		 3w6hB-3q31A:
28.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W6H_B_AZMB303_1
(CARBONIC ANHYDRASE 1)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		8 / 9 GLN A 121
HIS A 123
HIS A 125
GLU A 129
HIS A 142
LEU A 214
THR A 215
TRP A 225
 MLT  A   3 (-3.9A)
ZN  A   1 ( 3.2A)
ZN  A   1 (-3.3A)
ZN  A   1 ( 4.7A)
ZN  A   1 ( 3.2A)
MLT  A   3 ( 4.2A)
MLT  A   3 ( 4.3A)
MLT  A   3 (-4.9A)
 0.44A 3w6hB-3q31A:
23.5		 3w6hB-3q31A:
28.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W6H_B_AZMB303_1
(CARBONIC ANHYDRASE 1)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		5 / 9 HIS A 123
HIS A 142
LEU A 214
THR A 215
TRP A 225
 ZN  A   1 ( 3.2A)
ZN  A   1 ( 3.2A)
MLT  A   3 ( 4.2A)
MLT  A   3 ( 4.3A)
MLT  A   3 (-4.9A)
 1.50A 3w6hB-3q31A:
23.5		 3w6hB-3q31A:
28.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZNC_A_BZ1A500_1
(CARBONIC ANHYDRASE
IV)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		6 / 10 GLN A 102
HIS A 123
HIS A 125
HIS A 142
THR A 215
THR A 216
 None
ZN  A   1 ( 3.2A)
ZN  A   1 (-3.3A)
ZN  A   1 ( 3.2A)
MLT  A   3 ( 4.3A)
MLT  A   3 (-2.8A)
 0.96A 3zncA-3q31A:
23.9		 3zncA-3q31A:
27.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZNC_A_BZ1A500_1
(CARBONIC ANHYDRASE
IV)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		9 / 10 GLN A 121
HIS A 123
HIS A 125
HIS A 142
VAL A 144
LEU A 214
THR A 215
THR A 216
TRP A 225
 MLT  A   3 (-3.9A)
ZN  A   1 ( 3.2A)
ZN  A   1 (-3.3A)
ZN  A   1 ( 3.2A)
None
MLT  A   3 ( 4.2A)
MLT  A   3 ( 4.3A)
MLT  A   3 (-2.8A)
MLT  A   3 (-4.9A)
 0.53A 3zncA-3q31A:
23.9		 3zncA-3q31A:
27.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZNC_A_BZ1A500_1
(CARBONIC ANHYDRASE
IV)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		5 / 10 HIS A 125
VAL A 154
LEU A 214
THR A 215
THR A 216
 ZN  A   1 (-3.3A)
MLT  A   3 (-4.6A)
MLT  A   3 ( 4.2A)
MLT  A   3 ( 4.3A)
MLT  A   3 (-2.8A)
 0.90A 3zncA-3q31A:
23.9		 3zncA-3q31A:
27.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZNC_A_BZ1A500_1
(CARBONIC ANHYDRASE
IV)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		5 / 10 HIS A 142
HIS A 125
VAL A 154
LEU A 214
THR A 216
 ZN  A   1 ( 3.2A)
ZN  A   1 (-3.3A)
MLT  A   3 (-4.6A)
MLT  A   3 ( 4.2A)
MLT  A   3 (-2.8A)
 1.35A 3zncA-3q31A:
23.9		 3zncA-3q31A:
27.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZQE_B_DXCB1079_0
(PROTEIN PRGI, CELL
INVASION PROTEIN
SIPD)		 2fgq OUTER MEMBRANE PORIN
PROTEIN 32
(Delftia
acidovorans) 		5 / 11 SER X 186
THR X 102
LEU X 101
TYR X 104
SER X 184
 None
MLT  X 700 (-2.9A)
None
None
None
 1.45A 3zqeA-2fgqX:
0.0
3zqeB-2fgqX:
undetectable		 3zqeA-2fgqX:
22.99
3zqeB-2fgqX:
22.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AN2_A_EUIA1382_2
(DUAL SPECIFICITY
MITOGEN-ACTIVATED
PROTEIN KINASE
KINASE 1)		 6cty DIHYDROOROTASE
(Yersinia
pestis) 		4 / 4 ASN A  45
SER A  27
LEU A  26
THR A 111
 MLT  A 403 (-3.6A)
None
None
MLT  A 403 (-3.2A)
 1.40A 4an2A-6ctyA:
undetectable		 4an2A-6ctyA:
13.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AQ7_A_LEUA902_0
(LEUCINE--TRNA LIGASE)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		4 / 7 LEU A 214
GLU A 140
HIS A 142
HIS A 123
 MLT  A   3 ( 4.2A)
None
ZN  A   1 ( 3.2A)
ZN  A   1 ( 3.2A)
 1.26A 4aq7A-3q31A:
undetectable		 4aq7A-3q31A:
14.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4B17_A_SAMA1358_0
(RIBOSOMAL RNA LARGE
SUBUNIT
METHYLTRANSFERASE M)		 5ikm NS5 METHYL
TRANSFERASE
(Dengue
virus) 		7 / 12 SER A  56
GLY A  81
GLY A  85
GLY A  86
TRP A  87
ASP A 131
ASP A 146
 SAM  A 311 ( 2.7A)
SAM  A 311 (-3.2A)
SAM  A 311 ( 4.5A)
SAM  A 311 (-3.3A)
SAM  A 311 (-3.5A)
MLT  A 313 ( 2.6A)
SAM  A 311 (-3.8A)
 0.68A 4b17A-5ikmA:
12.4		 4b17A-5ikmA:
21.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4B3A_A_TACA222_1
(TETRACYCLINE
REPRESSOR PROTEIN
CLASS D)		 4a29 ENGINEERED
RETRO-ALDOL ENZYME
RA95.0
(synthetic
construct) 		5 / 12 LEU A 231
SER A 181
ARG A 223
GLN A 194
ILE A 198
 None
MLT  A 300 ( 4.4A)
None
None
None
 1.42A 4b3aA-4a29A:
undetectable		 4b3aA-4a29A:
20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C1D_B_X8ZB350_1
(BETA-LACTAMASE CLASS
B VIM-2)		 3g1p PROTEIN PHNP
(Escherichia
coli) 		5 / 10 HIS A  76
HIS A  78
ASP A  80
HIS A 143
HIS A 222
 MN  A 400 ( 3.4A)
MN  A 400 ( 3.3A)
MLT  A 500 ( 2.8A)
MN  A 400 ( 3.4A)
MN  A 401 (-3.7A)
 0.88A 4c1dB-3g1pA:
9.4		 4c1dB-3g1pA:
24.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C1F_A_X8ZA300_1
(BETA-LACTAMASE IMP-1)		 3g1p PROTEIN PHNP
(Escherichia
coli) 		5 / 11 HIS A  76
HIS A  78
ASP A  80
ASN A 199
HIS A 222
 MN  A 400 ( 3.4A)
MN  A 400 ( 3.3A)
MLT  A 500 ( 2.8A)
None
MN  A 401 (-3.7A)
 1.13A 4c1fA-3g1pA:
2.9
4c1fB-3g1pA:
7.3		 4c1fA-3g1pA:
19.56
4c1fB-3g1pA:
19.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C1F_A_X8ZA300_1
(BETA-LACTAMASE IMP-1)		 3g1p PROTEIN PHNP
(Escherichia
coli) 		5 / 11 HIS A  76
HIS A  78
ASP A  80
HIS A 143
HIS A 222
 MN  A 400 ( 3.4A)
MN  A 400 ( 3.3A)
MLT  A 500 ( 2.8A)
MN  A 400 ( 3.4A)
MN  A 401 (-3.7A)
 0.88A 4c1fA-3g1pA:
2.9
4c1fB-3g1pA:
7.3		 4c1fA-3g1pA:
19.56
4c1fB-3g1pA:
19.56
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4C2P_A_X8ZA709_1
(ANGIOTENSIN-CONVERTI
NG ENZYME)		 5a2r ANGIOTENSIN-CONVERTI
NG ENZYME
(Drosophila
melanogaster) 		11 / 11 GLN A 265
HIS A 337
HIS A 367
GLU A 368
HIS A 371
GLU A 395
PHE A 441
LYS A 495
HIS A 497
TYR A 504
TYR A 507
 MLT  A1615 (-3.2A)
MLT  A1615 (-3.8A)
ZN  A1616 (-3.2A)
MLT  A1615 (-4.3A)
ZN  A1616 (-3.3A)
ZN  A1616 (-2.4A)
MLT  A1615 ( 4.8A)
MLT  A1615 (-2.7A)
MLT  A1615 (-4.0A)
MLT  A1615 (-4.7A)
MLT  A1615 (-4.0A)
 0.36A 4c2pA-5a2rA:
52.0		 4c2pA-5a2rA:
44.59
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4C2P_A_X8ZA709_1
(ANGIOTENSIN-CONVERTI
NG ENZYME)		 5a2r ANGIOTENSIN-CONVERTI
NG ENZYME
(Drosophila
melanogaster) 		5 / 11 GLN A 265
HIS A 367
HIS A 371
GLU A 395
HIS A 337
 MLT  A1615 (-3.2A)
ZN  A1616 (-3.2A)
ZN  A1616 (-3.3A)
ZN  A1616 (-2.4A)
MLT  A1615 (-3.8A)
 1.44A 4c2pA-5a2rA:
52.0		 4c2pA-5a2rA:
44.59
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4C2P_A_X8ZA709_1
(ANGIOTENSIN-CONVERTI
NG ENZYME)		 5a2r ANGIOTENSIN-CONVERTI
NG ENZYME
(Drosophila
melanogaster) 		6 / 11 HIS A 337
HIS A 367
GLU A 368
HIS A 371
PHE A 511
TYR A 507
 MLT  A1615 (-3.8A)
ZN  A1616 (-3.2A)
MLT  A1615 (-4.3A)
ZN  A1616 (-3.3A)
None
MLT  A1615 (-4.0A)
 1.32A 4c2pA-5a2rA:
52.0		 4c2pA-5a2rA:
44.59
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4COQ_A_SANA300_1
(CARBONATE
DEHYDRATASE)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		6 / 10 GLN A 102
HIS A 123
HIS A 125
HIS A 142
THR A 215
THR A 216
 None
ZN  A   1 ( 3.2A)
ZN  A   1 (-3.3A)
ZN  A   1 ( 3.2A)
MLT  A   3 ( 4.3A)
MLT  A   3 (-2.8A)
 1.06A 4coqA-3q31A:
28.6		 4coqA-3q31A:
33.20
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4COQ_A_SANA300_1
(CARBONATE
DEHYDRATASE)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		10 / 10 GLN A 121
HIS A 123
HIS A 125
HIS A 142
VAL A 144
VAL A 154
LEU A 214
THR A 215
THR A 216
TRP A 225
 MLT  A   3 (-3.9A)
ZN  A   1 ( 3.2A)
ZN  A   1 (-3.3A)
ZN  A   1 ( 3.2A)
None
MLT  A   3 (-4.6A)
MLT  A   3 ( 4.2A)
MLT  A   3 ( 4.3A)
MLT  A   3 (-2.8A)
MLT  A   3 (-4.9A)
 0.32A 4coqA-3q31A:
28.6		 4coqA-3q31A:
33.20
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4COQ_A_SANA300_1
(CARBONATE
DEHYDRATASE)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		7 / 10 HIS A 123
HIS A 142
VAL A 154
LEU A 214
THR A 215
THR A 216
TRP A 225
 ZN  A   1 ( 3.2A)
ZN  A   1 ( 3.2A)
MLT  A   3 (-4.6A)
MLT  A   3 ( 4.2A)
MLT  A   3 ( 4.3A)
MLT  A   3 (-2.8A)
MLT  A   3 (-4.9A)
 1.42A 4coqA-3q31A:
28.6		 4coqA-3q31A:
33.20
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4COQ_A_SANA300_1
(CARBONATE
DEHYDRATASE)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		5 / 10 HIS A 125
VAL A 154
LEU A 214
THR A 215
THR A 216
 ZN  A   1 (-3.3A)
MLT  A   3 (-4.6A)
MLT  A   3 ( 4.2A)
MLT  A   3 ( 4.3A)
MLT  A   3 (-2.8A)
 0.94A 4coqA-3q31A:
28.6		 4coqA-3q31A:
33.20
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4COQ_A_SANA300_1
(CARBONATE
DEHYDRATASE)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		5 / 10 HIS A 142
HIS A 125
VAL A 154
LEU A 214
THR A 215
 ZN  A   1 ( 3.2A)
ZN  A   1 (-3.3A)
MLT  A   3 (-4.6A)
MLT  A   3 ( 4.2A)
MLT  A   3 ( 4.3A)
 1.35A 4coqA-3q31A:
28.6		 4coqA-3q31A:
33.20
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4COQ_B_SANB300_1
(CARBONATE
DEHYDRATASE)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		9 / 9 HIS A 123
HIS A 125
HIS A 142
VAL A 144
VAL A 154
LEU A 214
THR A 215
THR A 216
TRP A 225
 ZN  A   1 ( 3.2A)
ZN  A   1 (-3.3A)
ZN  A   1 ( 3.2A)
None
MLT  A   3 (-4.6A)
MLT  A   3 ( 4.2A)
MLT  A   3 ( 4.3A)
MLT  A   3 (-2.8A)
MLT  A   3 (-4.9A)
 0.29A 4coqB-3q31A:
28.5		 4coqB-3q31A:
33.20
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4COQ_B_SANB300_1
(CARBONATE
DEHYDRATASE)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		7 / 9 HIS A 123
HIS A 142
VAL A 154
LEU A 214
THR A 215
THR A 216
TRP A 225
 ZN  A   1 ( 3.2A)
ZN  A   1 ( 3.2A)
MLT  A   3 (-4.6A)
MLT  A   3 ( 4.2A)
MLT  A   3 ( 4.3A)
MLT  A   3 (-2.8A)
MLT  A   3 (-4.9A)
 1.43A 4coqB-3q31A:
28.5		 4coqB-3q31A:
33.20
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4COQ_B_SANB300_1
(CARBONATE
DEHYDRATASE)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		5 / 9 HIS A 125
VAL A 154
LEU A 214
THR A 215
THR A 216
 ZN  A   1 (-3.3A)
MLT  A   3 (-4.6A)
MLT  A   3 ( 4.2A)
MLT  A   3 ( 4.3A)
MLT  A   3 (-2.8A)
 0.96A 4coqB-3q31A:
28.5		 4coqB-3q31A:
33.20
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4CTJ_A_SAMA1263_0
(NON-STRUCTURAL
PROTEIN 5)		 5ikm NS5 METHYL
TRANSFERASE
(Dengue
virus) 		11 / 12 GLY A  58
GLY A  81
GLY A  83
GLY A  86
TRP A  87
THR A 104
LYS A 105
ASP A 131
VAL A 132
ASP A 146
ILE A 147
 SAM  A 311 (-3.3A)
SAM  A 311 (-3.2A)
SAM  A 311 (-3.3A)
SAM  A 311 (-3.3A)
SAM  A 311 (-3.5A)
SAM  A 311 (-4.5A)
MLT  A 313 ( 3.0A)
MLT  A 313 ( 2.6A)
SAM  A 311 (-3.7A)
SAM  A 311 (-3.8A)
SAM  A 311 ( 4.3A)
 0.52A 4ctjA-5ikmA:
43.0		 4ctjA-5ikmA:
80.73
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4CTJ_A_SAMA1263_0
(NON-STRUCTURAL
PROTEIN 5)		 5ikm NS5 METHYL
TRANSFERASE
(Dengue
virus) 		9 / 12 GLY A  81
GLY A  83
GLY A  86
THR A 104
LYS A 105
GLU A 111
ASP A 131
VAL A 132
ILE A 147
 SAM  A 311 (-3.2A)
SAM  A 311 (-3.3A)
SAM  A 311 (-3.3A)
SAM  A 311 (-4.5A)
MLT  A 313 ( 3.0A)
None
MLT  A 313 ( 2.6A)
SAM  A 311 (-3.7A)
SAM  A 311 ( 4.3A)
 0.78A 4ctjA-5ikmA:
43.0		 4ctjA-5ikmA:
80.73
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4CTJ_C_SAMC1263_0
(NON-STRUCTURAL
PROTEIN 5)		 5ikm NS5 METHYL
TRANSFERASE
(Dengue
virus) 		10 / 12 GLY A  58
GLY A  81
GLY A  83
GLY A  86
THR A 104
LYS A 105
HIS A 110
GLU A 111
VAL A 132
ILE A 147
 SAM  A 311 (-3.3A)
SAM  A 311 (-3.2A)
SAM  A 311 (-3.3A)
SAM  A 311 (-3.3A)
SAM  A 311 (-4.5A)
MLT  A 313 ( 3.0A)
SAM  A 311 (-4.1A)
None
SAM  A 311 (-3.7A)
SAM  A 311 ( 4.3A)
 0.62A 4ctjC-5ikmA:
42.7		 4ctjC-5ikmA:
80.73
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4CTJ_C_SAMC1263_0
(NON-STRUCTURAL
PROTEIN 5)		 5ikm NS5 METHYL
TRANSFERASE
(Dengue
virus) 		11 / 12 GLY A  58
GLY A  81
GLY A  83
GLY A  86
TRP A  87
THR A 104
LYS A 105
HIS A 110
VAL A 132
ASP A 146
ILE A 147
 SAM  A 311 (-3.3A)
SAM  A 311 (-3.2A)
SAM  A 311 (-3.3A)
SAM  A 311 (-3.3A)
SAM  A 311 (-3.5A)
SAM  A 311 (-4.5A)
MLT  A 313 ( 3.0A)
SAM  A 311 (-4.1A)
SAM  A 311 (-3.7A)
SAM  A 311 (-3.8A)
SAM  A 311 ( 4.3A)
 0.39A 4ctjC-5ikmA:
42.7		 4ctjC-5ikmA:
80.73
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4CTJ_C_SAMC1263_0
(NON-STRUCTURAL
PROTEIN 5)		 5ikm NS5 METHYL
TRANSFERASE
(Dengue
virus) 		6 / 12 GLY A  86
TRP A  87
LYS A 105
HIS A 110
ASP A 146
ILE A 147
 SAM  A 311 (-3.3A)
SAM  A 311 (-3.5A)
MLT  A 313 ( 3.0A)
SAM  A 311 (-4.1A)
SAM  A 311 (-3.8A)
SAM  A 311 ( 4.3A)
 1.46A 4ctjC-5ikmA:
42.7		 4ctjC-5ikmA:
80.73
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4CTK_A_SAMA1263_0
(POLYPROTEIN)		 5ikm NS5 METHYL
TRANSFERASE
(Dengue
virus) 		11 / 12 GLY A  58
GLY A  81
GLY A  83
GLY A  86
TRP A  87
THR A 104
LYS A 105
ASP A 131
VAL A 132
ASP A 146
ILE A 147
 SAM  A 311 (-3.3A)
SAM  A 311 (-3.2A)
SAM  A 311 (-3.3A)
SAM  A 311 (-3.3A)
SAM  A 311 (-3.5A)
SAM  A 311 (-4.5A)
MLT  A 313 ( 3.0A)
MLT  A 313 ( 2.6A)
SAM  A 311 (-3.7A)
SAM  A 311 (-3.8A)
SAM  A 311 ( 4.3A)
 0.47A 4ctkA-5ikmA:
42.8		 4ctkA-5ikmA:
80.73
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4CTK_C_SAMC1263_0
(POLYPROTEIN)		 5ikm NS5 METHYL
TRANSFERASE
(Dengue
virus) 		10 / 12 SER A  56
GLY A  58
GLY A  81
GLY A  83
GLY A  86
THR A 104
LYS A 105
GLU A 111
VAL A 132
ILE A 147
 SAM  A 311 ( 2.7A)
SAM  A 311 (-3.3A)
SAM  A 311 (-3.2A)
SAM  A 311 (-3.3A)
SAM  A 311 (-3.3A)
SAM  A 311 (-4.5A)
MLT  A 313 ( 3.0A)
None
SAM  A 311 (-3.7A)
SAM  A 311 ( 4.3A)
 0.66A 4ctkC-5ikmA:
42.6		 4ctkC-5ikmA:
80.73
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4CTK_C_SAMC1263_0
(POLYPROTEIN)		 5ikm NS5 METHYL
TRANSFERASE
(Dengue
virus) 		11 / 12 SER A  56
GLY A  58
GLY A  81
GLY A  83
GLY A  86
TRP A  87
THR A 104
LYS A 105
VAL A 132
ASP A 146
ILE A 147
 SAM  A 311 ( 2.7A)
SAM  A 311 (-3.3A)
SAM  A 311 (-3.2A)
SAM  A 311 (-3.3A)
SAM  A 311 (-3.3A)
SAM  A 311 (-3.5A)
SAM  A 311 (-4.5A)
MLT  A 313 ( 3.0A)
SAM  A 311 (-3.7A)
SAM  A 311 (-3.8A)
SAM  A 311 ( 4.3A)
 0.44A 4ctkC-5ikmA:
42.6		 4ctkC-5ikmA:
80.73
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4E3H_A_HQEA303_1
(CARBONIC ANHYDRASE 2)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		8 / 10 GLN A 121
VAL A 144
VAL A 154
LEU A 214
THR A 215
THR A 216
VAL A 223
TRP A 225
 MLT  A   3 (-3.9A)
None
MLT  A   3 (-4.6A)
MLT  A   3 ( 4.2A)
MLT  A   3 ( 4.3A)
MLT  A   3 (-2.8A)
None
MLT  A   3 (-4.9A)
 0.47A 4e3hA-3q31A:
24.5		 4e3hA-3q31A:
30.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EXS_B_X8ZB301_1
(BETA-LACTAMASE NDM-1)		 3g1p PROTEIN PHNP
(Escherichia
coli) 		4 / 8 HIS A  78
ASP A  80
HIS A 143
HIS A 222
 MN  A 400 ( 3.3A)
MLT  A 500 ( 2.8A)
MN  A 400 ( 3.4A)
MN  A 401 (-3.7A)
 0.87A 4exsB-3g1pA:
10.0		 4exsB-3g1pA:
19.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4G0C_A_AZMA302_1
(CARBONIC ANHYDRASE 2)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		7 / 11 GLN A 102
HIS A 123
HIS A 125
GLU A 129
HIS A 142
THR A 215
THR A 216
 None
ZN  A   1 ( 3.2A)
ZN  A   1 (-3.3A)
ZN  A   1 ( 4.7A)
ZN  A   1 ( 3.2A)
MLT  A   3 ( 4.3A)
MLT  A   3 (-2.8A)
 1.04A 4g0cA-3q31A:
24.3		 4g0cA-3q31A:
31.05
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4G0C_A_AZMA302_1
(CARBONIC ANHYDRASE 2)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		5 / 11 GLN A 121
HIS A 123
GLU A 140
VAL A 144
THR A 215
 MLT  A   3 (-3.9A)
ZN  A   1 ( 3.2A)
None
None
MLT  A   3 ( 4.3A)
 1.25A 4g0cA-3q31A:
24.3		 4g0cA-3q31A:
31.05
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4G0C_A_AZMA302_1
(CARBONIC ANHYDRASE 2)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		10 / 11 GLN A 121
HIS A 123
HIS A 125
GLU A 129
HIS A 142
VAL A 144
LEU A 214
THR A 215
THR A 216
TRP A 225
 MLT  A   3 (-3.9A)
ZN  A   1 ( 3.2A)
ZN  A   1 (-3.3A)
ZN  A   1 ( 4.7A)
ZN  A   1 ( 3.2A)
None
MLT  A   3 ( 4.2A)
MLT  A   3 ( 4.3A)
MLT  A   3 (-2.8A)
MLT  A   3 (-4.9A)
 0.33A 4g0cA-3q31A:
24.3		 4g0cA-3q31A:
31.05
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4G0C_A_AZMA302_1
(CARBONIC ANHYDRASE 2)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		6 / 11 GLN A 121
HIS A 123
HIS A 125
VAL A 144
LEU A 214
THR A 215
 MLT  A   3 (-3.9A)
ZN  A   1 ( 3.2A)
ZN  A   1 (-3.3A)
None
MLT  A   3 ( 4.2A)
MLT  A   3 ( 4.3A)
 1.45A 4g0cA-3q31A:
24.3		 4g0cA-3q31A:
31.05
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4G0C_A_AZMA302_1
(CARBONIC ANHYDRASE 2)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		6 / 11 HIS A 123
HIS A 142
LEU A 214
THR A 215
THR A 216
TRP A 225
 ZN  A   1 ( 3.2A)
ZN  A   1 ( 3.2A)
MLT  A   3 ( 4.2A)
MLT  A   3 ( 4.3A)
MLT  A   3 (-2.8A)
MLT  A   3 (-4.9A)
 1.44A 4g0cA-3q31A:
24.3		 4g0cA-3q31A:
31.05
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4G0C_A_AZMA302_1
(CARBONIC ANHYDRASE 2)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		6 / 11 HIS A 125
GLU A 129
VAL A 154
LEU A 214
THR A 215
THR A 216
 ZN  A   1 (-3.3A)
ZN  A   1 ( 4.7A)
MLT  A   3 (-4.6A)
MLT  A   3 ( 4.2A)
MLT  A   3 ( 4.3A)
MLT  A   3 (-2.8A)
 0.89A 4g0cA-3q31A:
24.3		 4g0cA-3q31A:
31.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G7A_A_AZMA302_1
(CARBONATE
DEHYDRATASE)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		8 / 11 GLN A 102
HIS A 123
HIS A 125
GLU A 129
HIS A 142
LEU A 214
THR A 215
THR A 216
 None
ZN  A   1 ( 3.2A)
ZN  A   1 (-3.3A)
ZN  A   1 ( 4.7A)
ZN  A   1 ( 3.2A)
MLT  A   3 ( 4.2A)
MLT  A   3 ( 4.3A)
MLT  A   3 (-2.8A)
 1.06A 4g7aA-3q31A:
27.7		 4g7aA-3q31A:
29.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G7A_A_AZMA302_1
(CARBONATE
DEHYDRATASE)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		7 / 11 GLN A 102
HIS A 125
GLU A 129
VAL A 144
LEU A 214
THR A 215
THR A 216
 None
ZN  A   1 (-3.3A)
ZN  A   1 ( 4.7A)
None
MLT  A   3 ( 4.2A)
MLT  A   3 ( 4.3A)
MLT  A   3 (-2.8A)
 1.27A 4g7aA-3q31A:
27.7		 4g7aA-3q31A:
29.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G7A_A_AZMA302_1
(CARBONATE
DEHYDRATASE)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		7 / 11 GLN A 121
HIS A 123
GLU A 140
HIS A 142
VAL A 144
VAL A 154
TRP A 225
 MLT  A   3 (-3.9A)
ZN  A   1 ( 3.2A)
None
ZN  A   1 ( 3.2A)
None
MLT  A   3 (-4.6A)
MLT  A   3 (-4.9A)
 1.45A 4g7aA-3q31A:
27.7		 4g7aA-3q31A:
29.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G7A_A_AZMA302_1
(CARBONATE
DEHYDRATASE)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		11 / 11 GLN A 121
HIS A 123
HIS A 125
GLU A 129
HIS A 142
VAL A 144
VAL A 154
LEU A 214
THR A 215
THR A 216
TRP A 225
 MLT  A   3 (-3.9A)
ZN  A   1 ( 3.2A)
ZN  A   1 (-3.3A)
ZN  A   1 ( 4.7A)
ZN  A   1 ( 3.2A)
None
MLT  A   3 (-4.6A)
MLT  A   3 ( 4.2A)
MLT  A   3 ( 4.3A)
MLT  A   3 (-2.8A)
MLT  A   3 (-4.9A)
 0.32A 4g7aA-3q31A:
27.7		 4g7aA-3q31A:
29.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G7A_A_AZMA302_1
(CARBONATE
DEHYDRATASE)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		6 / 11 GLN A 121
HIS A 123
HIS A 125
VAL A 144
LEU A 214
THR A 215
 MLT  A   3 (-3.9A)
ZN  A   1 ( 3.2A)
ZN  A   1 (-3.3A)
None
MLT  A   3 ( 4.2A)
MLT  A   3 ( 4.3A)
 1.42A 4g7aA-3q31A:
27.7		 4g7aA-3q31A:
29.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G7A_A_AZMA302_1
(CARBONATE
DEHYDRATASE)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		7 / 11 HIS A 123
HIS A 142
VAL A 154
LEU A 214
THR A 215
THR A 216
TRP A 225
 ZN  A   1 ( 3.2A)
ZN  A   1 ( 3.2A)
MLT  A   3 (-4.6A)
MLT  A   3 ( 4.2A)
MLT  A   3 ( 4.3A)
MLT  A   3 (-2.8A)
MLT  A   3 (-4.9A)
 1.40A 4g7aA-3q31A:
27.7		 4g7aA-3q31A:
29.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G7A_B_AZMB302_1
(CARBONATE
DEHYDRATASE)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		7 / 11 GLN A 102
HIS A 123
HIS A 125
GLU A 129
HIS A 142
THR A 215
THR A 216
 None
ZN  A   1 ( 3.2A)
ZN  A   1 (-3.3A)
ZN  A   1 ( 4.7A)
ZN  A   1 ( 3.2A)
MLT  A   3 ( 4.3A)
MLT  A   3 (-2.8A)
 0.99A 4g7aB-3q31A:
27.7		 4g7aB-3q31A:
29.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G7A_B_AZMB302_1
(CARBONATE
DEHYDRATASE)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		6 / 11 GLN A 102
HIS A 125
GLU A 129
VAL A 144
THR A 215
THR A 216
 None
ZN  A   1 (-3.3A)
ZN  A   1 ( 4.7A)
None
MLT  A   3 ( 4.3A)
MLT  A   3 (-2.8A)
 1.12A 4g7aB-3q31A:
27.7		 4g7aB-3q31A:
29.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G7A_B_AZMB302_1
(CARBONATE
DEHYDRATASE)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		7 / 11 GLN A 121
HIS A 123
GLU A 140
HIS A 142
VAL A 144
VAL A 154
TRP A 225
 MLT  A   3 (-3.9A)
ZN  A   1 ( 3.2A)
None
ZN  A   1 ( 3.2A)
None
MLT  A   3 (-4.6A)
MLT  A   3 (-4.9A)
 1.46A 4g7aB-3q31A:
27.7		 4g7aB-3q31A:
29.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G7A_B_AZMB302_1
(CARBONATE
DEHYDRATASE)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		11 / 11 GLN A 121
HIS A 123
HIS A 125
GLU A 129
HIS A 142
VAL A 144
VAL A 154
LEU A 214
THR A 215
THR A 216
TRP A 225
 MLT  A   3 (-3.9A)
ZN  A   1 ( 3.2A)
ZN  A   1 (-3.3A)
ZN  A   1 ( 4.7A)
ZN  A   1 ( 3.2A)
None
MLT  A   3 (-4.6A)
MLT  A   3 ( 4.2A)
MLT  A   3 ( 4.3A)
MLT  A   3 (-2.8A)
MLT  A   3 (-4.9A)
 0.31A 4g7aB-3q31A:
27.7		 4g7aB-3q31A:
29.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G7A_B_AZMB302_1
(CARBONATE
DEHYDRATASE)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		6 / 11 GLN A 121
HIS A 123
HIS A 125
VAL A 144
LEU A 214
THR A 215
 MLT  A   3 (-3.9A)
ZN  A   1 ( 3.2A)
ZN  A   1 (-3.3A)
None
MLT  A   3 ( 4.2A)
MLT  A   3 ( 4.3A)
 1.45A 4g7aB-3q31A:
27.7		 4g7aB-3q31A:
29.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G7A_B_AZMB302_1
(CARBONATE
DEHYDRATASE)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		7 / 11 HIS A 123
HIS A 142
VAL A 154
LEU A 214
THR A 215
THR A 216
TRP A 225
 ZN  A   1 ( 3.2A)
ZN  A   1 ( 3.2A)
MLT  A   3 (-4.6A)
MLT  A   3 ( 4.2A)
MLT  A   3 ( 4.3A)
MLT  A   3 (-2.8A)
MLT  A   3 (-4.9A)
 1.42A 4g7aB-3q31A:
27.7		 4g7aB-3q31A:
29.39
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4K0S_A_AZMA302_1
(CARBONIC ANHYDRASE 2)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		6 / 11 GLN A 102
HIS A 123
HIS A 125
HIS A 142
THR A 215
THR A 216
 None
ZN  A   1 ( 3.2A)
ZN  A   1 (-3.3A)
ZN  A   1 ( 3.2A)
MLT  A   3 ( 4.3A)
MLT  A   3 (-2.8A)
 1.09A 4k0sA-3q31A:
24.6		 4k0sA-3q31A:
31.77
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4K0S_A_AZMA302_1
(CARBONIC ANHYDRASE 2)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		5 / 11 GLN A 102
HIS A 125
VAL A 144
THR A 215
THR A 216
 None
ZN  A   1 (-3.3A)
None
MLT  A   3 ( 4.3A)
MLT  A   3 (-2.8A)
 1.16A 4k0sA-3q31A:
24.6		 4k0sA-3q31A:
31.77
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4K0S_A_AZMA302_1
(CARBONIC ANHYDRASE 2)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		10 / 11 GLN A 121
HIS A 123
HIS A 125
HIS A 142
VAL A 144
VAL A 154
LEU A 214
THR A 215
THR A 216
TRP A 225
 MLT  A   3 (-3.9A)
ZN  A   1 ( 3.2A)
ZN  A   1 (-3.3A)
ZN  A   1 ( 3.2A)
None
MLT  A   3 (-4.6A)
MLT  A   3 ( 4.2A)
MLT  A   3 ( 4.3A)
MLT  A   3 (-2.8A)
MLT  A   3 (-4.9A)
 0.37A 4k0sA-3q31A:
24.6		 4k0sA-3q31A:
31.77
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4K0S_A_AZMA302_1
(CARBONIC ANHYDRASE 2)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		7 / 11 HIS A 123
HIS A 142
VAL A 154
LEU A 214
THR A 215
THR A 216
TRP A 225
 ZN  A   1 ( 3.2A)
ZN  A   1 ( 3.2A)
MLT  A   3 (-4.6A)
MLT  A   3 ( 4.2A)
MLT  A   3 ( 4.3A)
MLT  A   3 (-2.8A)
MLT  A   3 (-4.9A)
 1.45A 4k0sA-3q31A:
24.6		 4k0sA-3q31A:
31.77
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4K0Z_A_MZMA308_1
(CARBONIC ANHYDRASE 2)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		11 / 12 GLN A 121
HIS A 123
HIS A 125
HIS A 142
VAL A 144
VAL A 154
LEU A 214
THR A 215
THR A 216
PRO A 218
TRP A 225
 MLT  A   3 (-3.9A)
ZN  A   1 ( 3.2A)
ZN  A   1 (-3.3A)
ZN  A   1 ( 3.2A)
None
MLT  A   3 (-4.6A)
MLT  A   3 ( 4.2A)
MLT  A   3 ( 4.3A)
MLT  A   3 (-2.8A)
None
MLT  A   3 (-4.9A)
 0.47A 4k0zA-3q31A:
24.5		 4k0zA-3q31A:
31.77
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4K0Z_A_MZMA308_1
(CARBONIC ANHYDRASE 2)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		8 / 12 HIS A 123
HIS A 142
VAL A 154
LEU A 214
THR A 215
THR A 216
PRO A 218
TRP A 225
 ZN  A   1 ( 3.2A)
ZN  A   1 ( 3.2A)
MLT  A   3 (-4.6A)
MLT  A   3 ( 4.2A)
MLT  A   3 ( 4.3A)
MLT  A   3 (-2.8A)
None
MLT  A   3 (-4.9A)
 1.40A 4k0zA-3q31A:
24.5		 4k0zA-3q31A:
31.77
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4K0Z_A_MZMA308_1
(CARBONIC ANHYDRASE 2)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		6 / 12 HIS A 125
HIS A 123
VAL A 144
LEU A 214
THR A 215
PRO A 218
 ZN  A   1 (-3.3A)
ZN  A   1 ( 3.2A)
None
MLT  A   3 ( 4.2A)
MLT  A   3 ( 4.3A)
None
 1.48A 4k0zA-3q31A:
24.5		 4k0zA-3q31A:
31.77
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4K0Z_A_MZMA308_1
(CARBONIC ANHYDRASE 2)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		6 / 12 HIS A 125
VAL A 144
LEU A 214
THR A 215
THR A 216
PRO A 218
 ZN  A   1 (-3.3A)
None
MLT  A   3 ( 4.2A)
MLT  A   3 ( 4.3A)
MLT  A   3 (-2.8A)
None
 1.02A 4k0zA-3q31A:
24.5		 4k0zA-3q31A:
31.77
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4K13_A_ETSA304_1
(CARBONIC ANHYDRASE 2)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		10 / 12 GLN A 121
HIS A 123
HIS A 125
HIS A 142
VAL A 144
VAL A 154
LEU A 214
THR A 215
THR A 216
TRP A 225
 MLT  A   3 (-3.9A)
ZN  A   1 ( 3.2A)
ZN  A   1 (-3.3A)
ZN  A   1 ( 3.2A)
None
MLT  A   3 (-4.6A)
MLT  A   3 ( 4.2A)
MLT  A   3 ( 4.3A)
MLT  A   3 (-2.8A)
MLT  A   3 (-4.9A)
 0.34A 4k13A-3q31A:
24.7		 4k13A-3q31A:
31.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LU3_A_AZMA302_1
(CARBONIC ANHYDRASE
14)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		7 / 11 GLN A 102
HIS A 123
HIS A 125
GLU A 129
HIS A 142
THR A 215
THR A 216
 None
ZN  A   1 ( 3.2A)
ZN  A   1 (-3.3A)
ZN  A   1 ( 4.7A)
ZN  A   1 ( 3.2A)
MLT  A   3 ( 4.3A)
MLT  A   3 (-2.8A)
 1.06A 4lu3A-3q31A:
24.8		 4lu3A-3q31A:
27.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LU3_A_AZMA302_1
(CARBONIC ANHYDRASE
14)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		6 / 11 GLN A 121
HIS A 123
GLU A 140
HIS A 142
VAL A 144
TRP A 225
 MLT  A   3 (-3.9A)
ZN  A   1 ( 3.2A)
None
ZN  A   1 ( 3.2A)
None
MLT  A   3 (-4.9A)
 1.46A 4lu3A-3q31A:
24.8		 4lu3A-3q31A:
27.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LU3_A_AZMA302_1
(CARBONIC ANHYDRASE
14)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		5 / 11 GLN A 121
HIS A 123
GLU A 140
VAL A 144
THR A 215
 MLT  A   3 (-3.9A)
ZN  A   1 ( 3.2A)
None
None
MLT  A   3 ( 4.3A)
 1.21A 4lu3A-3q31A:
24.8		 4lu3A-3q31A:
27.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LU3_A_AZMA302_1
(CARBONIC ANHYDRASE
14)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		10 / 11 GLN A 121
HIS A 123
HIS A 125
GLU A 129
HIS A 142
VAL A 144
LEU A 214
THR A 215
THR A 216
TRP A 225
 MLT  A   3 (-3.9A)
ZN  A   1 ( 3.2A)
ZN  A   1 (-3.3A)
ZN  A   1 ( 4.7A)
ZN  A   1 ( 3.2A)
None
MLT  A   3 ( 4.2A)
MLT  A   3 ( 4.3A)
MLT  A   3 (-2.8A)
MLT  A   3 (-4.9A)
 0.39A 4lu3A-3q31A:
24.8		 4lu3A-3q31A:
27.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LU3_A_AZMA302_1
(CARBONIC ANHYDRASE
14)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		6 / 11 GLN A 121
HIS A 123
HIS A 125
VAL A 144
LEU A 214
THR A 215
 MLT  A   3 (-3.9A)
ZN  A   1 ( 3.2A)
ZN  A   1 (-3.3A)
None
MLT  A   3 ( 4.2A)
MLT  A   3 ( 4.3A)
 1.38A 4lu3A-3q31A:
24.8		 4lu3A-3q31A:
27.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LU3_A_AZMA302_1
(CARBONIC ANHYDRASE
14)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		6 / 11 HIS A 123
HIS A 142
LEU A 214
THR A 215
THR A 216
TRP A 225
 ZN  A   1 ( 3.2A)
ZN  A   1 ( 3.2A)
MLT  A   3 ( 4.2A)
MLT  A   3 ( 4.3A)
MLT  A   3 (-2.8A)
MLT  A   3 (-4.9A)
 1.40A 4lu3A-3q31A:
24.8		 4lu3A-3q31A:
27.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LU3_A_AZMA302_1
(CARBONIC ANHYDRASE
14)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		6 / 11 HIS A 125
GLU A 129
VAL A 154
LEU A 214
THR A 215
THR A 216
 ZN  A   1 (-3.3A)
ZN  A   1 ( 4.7A)
MLT  A   3 (-4.6A)
MLT  A   3 ( 4.2A)
MLT  A   3 ( 4.3A)
MLT  A   3 (-2.8A)
 0.84A 4lu3A-3q31A:
24.8		 4lu3A-3q31A:
27.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4M2R_A_BZ1A302_1
(CARBONIC ANHYDRASE 2)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		6 / 12 GLN A 121
HIS A 123
HIS A 125
VAL A 144
LEU A 214
THR A 215
 MLT  A   3 (-3.9A)
ZN  A   1 ( 3.2A)
ZN  A   1 (-3.3A)
None
MLT  A   3 ( 4.2A)
MLT  A   3 ( 4.3A)
 1.42A 4m2rA-3q31A:
24.4		 4m2rA-3q31A:
31.05
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4M2R_A_BZ1A302_1
(CARBONIC ANHYDRASE 2)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		10 / 12 GLN A 121
HIS A 123
HIS A 125
VAL A 144
VAL A 154
LEU A 214
THR A 215
THR A 216
PRO A 218
TRP A 225
 MLT  A   3 (-3.9A)
ZN  A   1 ( 3.2A)
ZN  A   1 (-3.3A)
None
MLT  A   3 (-4.6A)
MLT  A   3 ( 4.2A)
MLT  A   3 ( 4.3A)
MLT  A   3 (-2.8A)
None
MLT  A   3 (-4.9A)
 0.43A 4m2rA-3q31A:
24.4		 4m2rA-3q31A:
31.05
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4M2R_A_BZ1A302_1
(CARBONIC ANHYDRASE 2)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		7 / 12 GLN A 121
HIS A 123
VAL A 144
LEU A 214
THR A 215
PRO A 217
TRP A 225
 MLT  A   3 (-3.9A)
ZN  A   1 ( 3.2A)
None
MLT  A   3 ( 4.2A)
MLT  A   3 ( 4.3A)
None
MLT  A   3 (-4.9A)
 1.35A 4m2rA-3q31A:
24.4		 4m2rA-3q31A:
31.05
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4M2R_A_BZ1A302_1
(CARBONIC ANHYDRASE 2)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		6 / 12 HIS A 123
VAL A 154
LEU A 214
THR A 216
PRO A 218
TRP A 225
 ZN  A   1 ( 3.2A)
MLT  A   3 (-4.6A)
MLT  A   3 ( 4.2A)
MLT  A   3 (-2.8A)
None
MLT  A   3 (-4.9A)
 1.28A 4m2rA-3q31A:
24.4		 4m2rA-3q31A:
31.05
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4M2R_A_BZ1A302_1
(CARBONIC ANHYDRASE 2)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		6 / 12 HIS A 142
HIS A 125
VAL A 154
LEU A 214
THR A 216
PRO A 218
 ZN  A   1 ( 3.2A)
ZN  A   1 (-3.3A)
MLT  A   3 (-4.6A)
MLT  A   3 ( 4.2A)
MLT  A   3 (-2.8A)
None
 1.49A 4m2rA-3q31A:
24.4		 4m2rA-3q31A:
31.05
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4M2U_A_ETSA302_1
(CARBONIC ANHYDRASE 2)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		9 / 12 GLN A 121
HIS A 123
HIS A 125
VAL A 144
VAL A 154
LEU A 214
THR A 215
THR A 216
TRP A 225
 MLT  A   3 (-3.9A)
ZN  A   1 ( 3.2A)
ZN  A   1 (-3.3A)
None
MLT  A   3 (-4.6A)
MLT  A   3 ( 4.2A)
MLT  A   3 ( 4.3A)
MLT  A   3 (-2.8A)
MLT  A   3 (-4.9A)
 0.38A 4m2uA-3q31A:
24.4		 4m2uA-3q31A:
31.05
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4M2U_A_ETSA302_1
(CARBONIC ANHYDRASE 2)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		8 / 12 TRP A  48
HIS A 123
HIS A 125
VAL A 144
VAL A 154
LEU A 214
THR A 216
TRP A 225
 None
ZN  A   1 ( 3.2A)
ZN  A   1 (-3.3A)
None
MLT  A   3 (-4.6A)
MLT  A   3 ( 4.2A)
MLT  A   3 (-2.8A)
MLT  A   3 (-4.9A)
 1.30A 4m2uA-3q31A:
24.4		 4m2uA-3q31A:
31.05
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4M2V_A_BZ1A302_1
(CARBONIC ANHYDRASE 2)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		6 / 12 GLN A 121
HIS A 123
HIS A 125
VAL A 144
LEU A 214
THR A 215
 MLT  A   3 (-3.9A)
ZN  A   1 ( 3.2A)
ZN  A   1 (-3.3A)
None
MLT  A   3 ( 4.2A)
MLT  A   3 ( 4.3A)
 1.45A 4m2vA-3q31A:
24.5		 4m2vA-3q31A:
31.41
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4M2V_A_BZ1A302_1
(CARBONIC ANHYDRASE 2)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		9 / 12 GLN A 121
HIS A 123
HIS A 125
VAL A 144
VAL A 154
LEU A 214
THR A 215
THR A 216
TRP A 225
 MLT  A   3 (-3.9A)
ZN  A   1 ( 3.2A)
ZN  A   1 (-3.3A)
None
MLT  A   3 (-4.6A)
MLT  A   3 ( 4.2A)
MLT  A   3 ( 4.3A)
MLT  A   3 (-2.8A)
MLT  A   3 (-4.9A)
 0.36A 4m2vA-3q31A:
24.5		 4m2vA-3q31A:
31.41
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4M2V_A_BZ1A302_1
(CARBONIC ANHYDRASE 2)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		6 / 12 HIS A 123
VAL A 154
LEU A 214
THR A 215
THR A 216
TRP A 225
 ZN  A   1 ( 3.2A)
MLT  A   3 (-4.6A)
MLT  A   3 ( 4.2A)
MLT  A   3 ( 4.3A)
MLT  A   3 (-2.8A)
MLT  A   3 (-4.9A)
 1.36A 4m2vA-3q31A:
24.5		 4m2vA-3q31A:
31.41
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4M2W_A_ETSA302_1
(CARBONIC ANHYDRASE 2)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		10 / 12 GLN A 121
HIS A 123
HIS A 125
HIS A 142
VAL A 144
VAL A 154
LEU A 214
THR A 215
THR A 216
TRP A 225
 MLT  A   3 (-3.9A)
ZN  A   1 ( 3.2A)
ZN  A   1 (-3.3A)
ZN  A   1 ( 3.2A)
None
MLT  A   3 (-4.6A)
MLT  A   3 ( 4.2A)
MLT  A   3 ( 4.3A)
MLT  A   3 (-2.8A)
MLT  A   3 (-4.9A)
 0.35A 4m2wA-3q31A:
24.4		 4m2wA-3q31A:
31.77
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4M2W_A_ETSA302_1
(CARBONIC ANHYDRASE 2)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		6 / 12 GLN A 121
HIS A 123
HIS A 125
VAL A 144
LEU A 214
THR A 215
 MLT  A   3 (-3.9A)
ZN  A   1 ( 3.2A)
ZN  A   1 (-3.3A)
None
MLT  A   3 ( 4.2A)
MLT  A   3 ( 4.3A)
 1.44A 4m2wA-3q31A:
24.4		 4m2wA-3q31A:
31.77
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4M2W_A_ETSA302_1
(CARBONIC ANHYDRASE 2)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		6 / 12 HIS A 123
HIS A 142
VAL A 154
LEU A 214
THR A 216
TRP A 225
 ZN  A   1 ( 3.2A)
ZN  A   1 ( 3.2A)
MLT  A   3 (-4.6A)
MLT  A   3 ( 4.2A)
MLT  A   3 (-2.8A)
MLT  A   3 (-4.9A)
 1.50A 4m2wA-3q31A:
24.4		 4m2wA-3q31A:
31.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MME_B_29QB603_1
(TRANSPORTER)		 4nml RIBULOSE 5-PHOSPHATE
ISOMERASE
(Toxoplasma
gondii) 		5 / 9 ASP A  91
ALA A 239
GLY A 233
PHE A 235
GLY A  99
 MLT  A 303 (-4.5A)
None
None
None
None
 1.21A 4mmeB-4nmlA:
undetectable		 4mmeB-4nmlA:
20.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MMF_B_29QB603_1
(TRANSPORTER)		 4nml RIBULOSE 5-PHOSPHATE
ISOMERASE
(Toxoplasma
gondii) 		5 / 9 ASP A  91
ALA A 239
GLY A 233
PHE A 235
GLY A  99
 MLT  A 303 (-4.5A)
None
None
None
None
 1.17A 4mmfB-4nmlA:
undetectable		 4mmfB-4nmlA:
20.80
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4N16_A_CHDA301_0
(CARBONIC ANHYDRASE 2)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		6 / 8 GLN A 102
HIS A 123
HIS A 125
HIS A 142
THR A 215
THR A 216
 None
ZN  A   1 ( 3.2A)
ZN  A   1 (-3.3A)
ZN  A   1 ( 3.2A)
MLT  A   3 ( 4.3A)
MLT  A   3 (-2.8A)
 1.10A 4n16A-3q31A:
24.6		 4n16A-3q31A:
30.69
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4N16_A_CHDA301_0
(CARBONIC ANHYDRASE 2)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		6 / 8 GLN A 121
HIS A 123
HIS A 125
HIS A 142
THR A 215
THR A 216
 MLT  A   3 (-3.9A)
ZN  A   1 ( 3.2A)
ZN  A   1 (-3.3A)
ZN  A   1 ( 3.2A)
MLT  A   3 ( 4.3A)
MLT  A   3 (-2.8A)
 0.42A 4n16A-3q31A:
24.6		 4n16A-3q31A:
30.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OLT_A_GCSA303_1
(CHITOSANASE)		 2g76 D-3-PHOSPHOGLYCERATE
DEHYDROGENASE
(Homo
sapiens) 		4 / 6 ASP A  80
ARG A 235
GLY A 237
HIS A 282
 None
MLT  A 503 ( 2.8A)
None
MLT  A 503 ( 3.9A)
 0.91A 4oltA-2g76A:
undetectable		 4oltA-2g76A:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OLT_B_GCSB303_1
(CHITOSANASE)		 2g76 D-3-PHOSPHOGLYCERATE
DEHYDROGENASE
(Homo
sapiens) 		4 / 6 ASP A  80
ARG A 235
GLY A 237
HIS A 282
 None
MLT  A 503 ( 2.8A)
None
MLT  A 503 ( 3.9A)
 0.92A 4oltB-2g76A:
undetectable		 4oltB-2g76A:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P6V_E_RBFE201_1
(NA(+)-TRANSLOCATING
NADH-QUINONE
REDUCTASE SUBUNIT B
NA(+)-TRANSLOCATING
NADH-QUINONE
REDUCTASE SUBUNIT E)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		4 / 5 HIS A 142
VAL A 141
GLU A 140
VAL A 154
 ZN  A   1 ( 3.2A)
None
None
MLT  A   3 (-4.6A)
 1.27A 4p6vB-3q31A:
undetectable
4p6vE-3q31A:
undetectable		 4p6vB-3q31A:
21.88
4p6vE-3q31A:
23.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PEV_C_ADNC501_2
(MEMBRANE LIPOPROTEIN
FAMILY PROTEIN)		 5cuv ACIDOCALCISOMAL
PYROPHOSPHATASE
(Trypanosoma
cruzi) 		3 / 3 PRO A 274
VAL A 313
HIS A 336
 None
None
MLT  A 501 (-4.2A)
 0.61A 4pevC-5cuvA:
undetectable		 4pevC-5cuvA:
22.87
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4PXX_A_CHDA302_0
(CARBONIC ANHYDRASE 2)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		6 / 9 GLN A 102
HIS A 123
HIS A 125
HIS A 142
THR A 215
THR A 216
 None
ZN  A   1 ( 3.2A)
ZN  A   1 (-3.3A)
ZN  A   1 ( 3.2A)
MLT  A   3 ( 4.3A)
MLT  A   3 (-2.8A)
 1.06A 4pxxA-3q31A:
24.6		 4pxxA-3q31A:
30.69
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4PXX_A_CHDA302_0
(CARBONIC ANHYDRASE 2)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		6 / 9 GLN A 121
HIS A 123
HIS A 125
HIS A 142
THR A 215
THR A 216
 MLT  A   3 (-3.9A)
ZN  A   1 ( 3.2A)
ZN  A   1 (-3.3A)
ZN  A   1 ( 3.2A)
MLT  A   3 ( 4.3A)
MLT  A   3 (-2.8A)
 0.36A 4pxxA-3q31A:
24.6		 4pxxA-3q31A:
30.69
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4PXX_A_CHDA302_0
(CARBONIC ANHYDRASE 2)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		6 / 9 GLU A  95
HIS A 123
HIS A 125
HIS A 142
THR A 215
THR A 216
 None
ZN  A   1 ( 3.2A)
ZN  A   1 (-3.3A)
ZN  A   1 ( 3.2A)
MLT  A   3 ( 4.3A)
MLT  A   3 (-2.8A)
 1.07A 4pxxA-3q31A:
24.6		 4pxxA-3q31A:
30.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R7L_A_SHHA709_1
(LEUKOTRIENE A-4
HYDROLASE)		 5a2r ANGIOTENSIN-CONVERTI
NG ENZYME
(Drosophila
melanogaster) 		5 / 12 HIS A 367
GLU A 368
HIS A 371
GLU A 395
TYR A 507
 ZN  A1616 (-3.2A)
MLT  A1615 (-4.3A)
ZN  A1616 (-3.3A)
ZN  A1616 (-2.4A)
MLT  A1615 (-4.0A)
 0.65A 4r7lA-5a2rA:
3.7		 4r7lA-5a2rA:
20.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RZV_B_032B801_2
(SERINE/THREONINE-PRO
TEIN KINASE B-RAF)		 5a2r ANGIOTENSIN-CONVERTI
NG ENZYME
(Drosophila
melanogaster) 		4 / 5 PHE A 306
SER A 339
HIS A 337
ASP A 399
 None
None
MLT  A1615 (-3.8A)
None
 1.13A 4rzvB-5a2rA:
undetectable		 4rzvB-5a2rA:
16.61
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4TWL_A_ASCA303_0
(DIOSCORIN 5)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		5 / 10 HIS A 125
VAL A 144
VAL A 154
THR A 215
TRP A 225
 ZN  A   1 (-3.3A)
None
MLT  A   3 (-4.6A)
MLT  A   3 ( 4.3A)
MLT  A   3 (-4.9A)
 0.31A 4twlA-3q31A:
26.2		 4twlA-3q31A:
30.08
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4TWL_B_ASCB304_0
(DIOSCORIN 5)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		5 / 10 HIS A 125
VAL A 144
VAL A 154
THR A 215
TRP A 225
 ZN  A   1 (-3.3A)
None
MLT  A   3 (-4.6A)
MLT  A   3 ( 4.3A)
MLT  A   3 (-4.9A)
 0.28A 4twlB-3q31A:
26.6		 4twlB-3q31A:
30.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UCK_B_SAMB2409_1
(RNA-DIRECTED RNA
POLYMERASE L)		 5ikm NS5 METHYL
TRANSFERASE
(Dengue
virus) 		4 / 6 SER A  56
GLY A  81
ASP A 131
ASP A 146
 SAM  A 311 ( 2.7A)
SAM  A 311 (-3.2A)
MLT  A 313 ( 2.6A)
SAM  A 311 (-3.8A)
 0.57A 4uckB-5ikmA:
9.5		 4uckB-5ikmA:
19.53
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4UOV_A_AZMA299_1
(CARBONATE
DEHYDRATASE)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		7 / 11 GLN A 102
HIS A 123
HIS A 125
GLU A 129
HIS A 142
THR A 215
THR A 216
 None
ZN  A   1 ( 3.2A)
ZN  A   1 (-3.3A)
ZN  A   1 ( 4.7A)
ZN  A   1 ( 3.2A)
MLT  A   3 ( 4.3A)
MLT  A   3 (-2.8A)
 1.03A 4uovA-3q31A:
28.2		 4uovA-3q31A:
33.20
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4UOV_A_AZMA299_1
(CARBONATE
DEHYDRATASE)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		5 / 11 GLN A 102
HIS A 125
VAL A 144
THR A 215
THR A 216
 None
ZN  A   1 (-3.3A)
None
MLT  A   3 ( 4.3A)
MLT  A   3 (-2.8A)
 1.11A 4uovA-3q31A:
28.2		 4uovA-3q31A:
33.20
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4UOV_A_AZMA299_1
(CARBONATE
DEHYDRATASE)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		7 / 11 GLN A 121
HIS A 123
GLU A 140
HIS A 142
VAL A 144
VAL A 154
TRP A 225
 MLT  A   3 (-3.9A)
ZN  A   1 ( 3.2A)
None
ZN  A   1 ( 3.2A)
None
MLT  A   3 (-4.6A)
MLT  A   3 (-4.9A)
 1.49A 4uovA-3q31A:
28.2		 4uovA-3q31A:
33.20
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4UOV_A_AZMA299_1
(CARBONATE
DEHYDRATASE)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		5 / 11 GLN A 121
HIS A 123
GLU A 140
VAL A 144
THR A 215
 MLT  A   3 (-3.9A)
ZN  A   1 ( 3.2A)
None
None
MLT  A   3 ( 4.3A)
 1.21A 4uovA-3q31A:
28.2		 4uovA-3q31A:
33.20
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4UOV_A_AZMA299_1
(CARBONATE
DEHYDRATASE)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		11 / 11 GLN A 121
HIS A 123
HIS A 125
GLU A 129
HIS A 142
VAL A 144
VAL A 154
LEU A 214
THR A 215
THR A 216
TRP A 225
 MLT  A   3 (-3.9A)
ZN  A   1 ( 3.2A)
ZN  A   1 (-3.3A)
ZN  A   1 ( 4.7A)
ZN  A   1 ( 3.2A)
None
MLT  A   3 (-4.6A)
MLT  A   3 ( 4.2A)
MLT  A   3 ( 4.3A)
MLT  A   3 (-2.8A)
MLT  A   3 (-4.9A)
 0.35A 4uovA-3q31A:
28.2		 4uovA-3q31A:
33.20
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4UOV_A_AZMA299_1
(CARBONATE
DEHYDRATASE)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		7 / 11 HIS A 123
HIS A 142
VAL A 154
LEU A 214
THR A 215
THR A 216
TRP A 225
 ZN  A   1 ( 3.2A)
ZN  A   1 ( 3.2A)
MLT  A   3 (-4.6A)
MLT  A   3 ( 4.2A)
MLT  A   3 ( 4.3A)
MLT  A   3 (-2.8A)
MLT  A   3 (-4.9A)
 1.41A 4uovA-3q31A:
28.2		 4uovA-3q31A:
33.20
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4UOV_A_AZMA299_1
(CARBONATE
DEHYDRATASE)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		6 / 11 HIS A 125
GLU A 129
VAL A 154
LEU A 214
THR A 215
THR A 216
 ZN  A   1 (-3.3A)
ZN  A   1 ( 4.7A)
MLT  A   3 (-4.6A)
MLT  A   3 ( 4.2A)
MLT  A   3 ( 4.3A)
MLT  A   3 (-2.8A)
 0.98A 4uovA-3q31A:
28.2		 4uovA-3q31A:
33.20
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4UOV_B_AZMB299_1
(CARBONATE
DEHYDRATASE)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		7 / 11 GLN A 102
HIS A 123
HIS A 125
GLU A 129
HIS A 142
THR A 215
THR A 216
 None
ZN  A   1 ( 3.2A)
ZN  A   1 (-3.3A)
ZN  A   1 ( 4.7A)
ZN  A   1 ( 3.2A)
MLT  A   3 ( 4.3A)
MLT  A   3 (-2.8A)
 1.03A 4uovB-3q31A:
28.3		 4uovB-3q31A:
33.20
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4UOV_B_AZMB299_1
(CARBONATE
DEHYDRATASE)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		5 / 11 GLN A 102
HIS A 125
VAL A 144
THR A 215
THR A 216
 None
ZN  A   1 (-3.3A)
None
MLT  A   3 ( 4.3A)
MLT  A   3 (-2.8A)
 1.09A 4uovB-3q31A:
28.3		 4uovB-3q31A:
33.20
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4UOV_B_AZMB299_1
(CARBONATE
DEHYDRATASE)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		7 / 11 GLN A 121
HIS A 123
GLU A 140
HIS A 142
VAL A 144
VAL A 154
TRP A 225
 MLT  A   3 (-3.9A)
ZN  A   1 ( 3.2A)
None
ZN  A   1 ( 3.2A)
None
MLT  A   3 (-4.6A)
MLT  A   3 (-4.9A)
 1.48A 4uovB-3q31A:
28.3		 4uovB-3q31A:
33.20
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4UOV_B_AZMB299_1
(CARBONATE
DEHYDRATASE)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		5 / 11 GLN A 121
HIS A 123
GLU A 140
VAL A 144
THR A 215
 MLT  A   3 (-3.9A)
ZN  A   1 ( 3.2A)
None
None
MLT  A   3 ( 4.3A)
 1.18A 4uovB-3q31A:
28.3		 4uovB-3q31A:
33.20
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4UOV_B_AZMB299_1
(CARBONATE
DEHYDRATASE)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		11 / 11 GLN A 121
HIS A 123
HIS A 125
GLU A 129
HIS A 142
VAL A 144
VAL A 154
LEU A 214
THR A 215
THR A 216
TRP A 225
 MLT  A   3 (-3.9A)
ZN  A   1 ( 3.2A)
ZN  A   1 (-3.3A)
ZN  A   1 ( 4.7A)
ZN  A   1 ( 3.2A)
None
MLT  A   3 (-4.6A)
MLT  A   3 ( 4.2A)
MLT  A   3 ( 4.3A)
MLT  A   3 (-2.8A)
MLT  A   3 (-4.9A)
 0.31A 4uovB-3q31A:
28.3		 4uovB-3q31A:
33.20
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4UOV_B_AZMB299_1
(CARBONATE
DEHYDRATASE)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		6 / 11 GLN A 121
HIS A 123
HIS A 125
VAL A 144
LEU A 214
THR A 215
 MLT  A   3 (-3.9A)
ZN  A   1 ( 3.2A)
ZN  A   1 (-3.3A)
None
MLT  A   3 ( 4.2A)
MLT  A   3 ( 4.3A)
 1.49A 4uovB-3q31A:
28.3		 4uovB-3q31A:
33.20
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4UOV_B_AZMB299_1
(CARBONATE
DEHYDRATASE)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		7 / 11 HIS A 123
HIS A 142
VAL A 154
LEU A 214
THR A 215
THR A 216
TRP A 225
 ZN  A   1 ( 3.2A)
ZN  A   1 ( 3.2A)
MLT  A   3 (-4.6A)
MLT  A   3 ( 4.2A)
MLT  A   3 ( 4.3A)
MLT  A   3 (-2.8A)
MLT  A   3 (-4.9A)
 1.42A 4uovB-3q31A:
28.3		 4uovB-3q31A:
33.20
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4UOV_B_AZMB299_1
(CARBONATE
DEHYDRATASE)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		6 / 11 HIS A 125
GLU A 129
VAL A 154
LEU A 214
THR A 215
THR A 216
 ZN  A   1 (-3.3A)
ZN  A   1 ( 4.7A)
MLT  A   3 (-4.6A)
MLT  A   3 ( 4.2A)
MLT  A   3 ( 4.3A)
MLT  A   3 (-2.8A)
 0.95A 4uovB-3q31A:
28.3		 4uovB-3q31A:
33.20
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4UOV_C_AZMC299_1
(CARBONATE
DEHYDRATASE)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		7 / 11 GLN A 102
HIS A 123
HIS A 125
GLU A 129
HIS A 142
THR A 215
THR A 216
 None
ZN  A   1 ( 3.2A)
ZN  A   1 (-3.3A)
ZN  A   1 ( 4.7A)
ZN  A   1 ( 3.2A)
MLT  A   3 ( 4.3A)
MLT  A   3 (-2.8A)
 1.05A 4uovC-3q31A:
28.1		 4uovC-3q31A:
33.20
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4UOV_C_AZMC299_1
(CARBONATE
DEHYDRATASE)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		5 / 11 GLN A 102
HIS A 125
VAL A 144
THR A 215
THR A 216
 None
ZN  A   1 (-3.3A)
None
MLT  A   3 ( 4.3A)
MLT  A   3 (-2.8A)
 1.11A 4uovC-3q31A:
28.1		 4uovC-3q31A:
33.20
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4UOV_C_AZMC299_1
(CARBONATE
DEHYDRATASE)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		11 / 11 GLN A 121
HIS A 123
HIS A 125
GLU A 129
HIS A 142
VAL A 144
VAL A 154
LEU A 214
THR A 215
THR A 216
TRP A 225
 MLT  A   3 (-3.9A)
ZN  A   1 ( 3.2A)
ZN  A   1 (-3.3A)
ZN  A   1 ( 4.7A)
ZN  A   1 ( 3.2A)
None
MLT  A   3 (-4.6A)
MLT  A   3 ( 4.2A)
MLT  A   3 ( 4.3A)
MLT  A   3 (-2.8A)
MLT  A   3 (-4.9A)
 0.36A 4uovC-3q31A:
28.1		 4uovC-3q31A:
33.20
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4UOV_C_AZMC299_1
(CARBONATE
DEHYDRATASE)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		7 / 11 HIS A 123
HIS A 142
VAL A 154
LEU A 214
THR A 215
THR A 216
TRP A 225
 ZN  A   1 ( 3.2A)
ZN  A   1 ( 3.2A)
MLT  A   3 (-4.6A)
MLT  A   3 ( 4.2A)
MLT  A   3 ( 4.3A)
MLT  A   3 (-2.8A)
MLT  A   3 (-4.9A)
 1.43A 4uovC-3q31A:
28.1		 4uovC-3q31A:
33.20
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4UOV_C_AZMC299_1
(CARBONATE
DEHYDRATASE)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		6 / 11 HIS A 125
GLU A 129
VAL A 154
LEU A 214
THR A 215
THR A 216
 ZN  A   1 (-3.3A)
ZN  A   1 ( 4.7A)
MLT  A   3 (-4.6A)
MLT  A   3 ( 4.2A)
MLT  A   3 ( 4.3A)
MLT  A   3 (-2.8A)
 0.98A 4uovC-3q31A:
28.1		 4uovC-3q31A:
33.20
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4UOV_D_AZMD299_1
(CARBONATE
DEHYDRATASE)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		7 / 11 GLN A 102
HIS A 123
HIS A 125
GLU A 129
HIS A 142
THR A 215
THR A 216
 None
ZN  A   1 ( 3.2A)
ZN  A   1 (-3.3A)
ZN  A   1 ( 4.7A)
ZN  A   1 ( 3.2A)
MLT  A   3 ( 4.3A)
MLT  A   3 (-2.8A)
 1.04A 4uovD-3q31A:
28.2		 4uovD-3q31A:
33.20
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4UOV_D_AZMD299_1
(CARBONATE
DEHYDRATASE)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		6 / 11 GLN A 102
HIS A 123
HIS A 125
VAL A 144
THR A 215
THR A 216
 None
ZN  A   1 ( 3.2A)
ZN  A   1 (-3.3A)
None
MLT  A   3 ( 4.3A)
MLT  A   3 (-2.8A)
 1.17A 4uovD-3q31A:
28.2		 4uovD-3q31A:
33.20
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4UOV_D_AZMD299_1
(CARBONATE
DEHYDRATASE)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		7 / 11 GLN A 121
HIS A 123
GLU A 140
HIS A 142
VAL A 144
VAL A 154
TRP A 225
 MLT  A   3 (-3.9A)
ZN  A   1 ( 3.2A)
None
ZN  A   1 ( 3.2A)
None
MLT  A   3 (-4.6A)
MLT  A   3 (-4.9A)
 1.49A 4uovD-3q31A:
28.2		 4uovD-3q31A:
33.20
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4UOV_D_AZMD299_1
(CARBONATE
DEHYDRATASE)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		5 / 11 GLN A 121
HIS A 123
GLU A 140
VAL A 144
THR A 215
 MLT  A   3 (-3.9A)
ZN  A   1 ( 3.2A)
None
None
MLT  A   3 ( 4.3A)
 1.21A 4uovD-3q31A:
28.2		 4uovD-3q31A:
33.20
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4UOV_D_AZMD299_1
(CARBONATE
DEHYDRATASE)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		11 / 11 GLN A 121
HIS A 123
HIS A 125
GLU A 129
HIS A 142
VAL A 144
VAL A 154
LEU A 214
THR A 215
THR A 216
TRP A 225
 MLT  A   3 (-3.9A)
ZN  A   1 ( 3.2A)
ZN  A   1 (-3.3A)
ZN  A   1 ( 4.7A)
ZN  A   1 ( 3.2A)
None
MLT  A   3 (-4.6A)
MLT  A   3 ( 4.2A)
MLT  A   3 ( 4.3A)
MLT  A   3 (-2.8A)
MLT  A   3 (-4.9A)
 0.36A 4uovD-3q31A:
28.2		 4uovD-3q31A:
33.20
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4UOV_D_AZMD299_1
(CARBONATE
DEHYDRATASE)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		6 / 11 HIS A 123
HIS A 125
VAL A 144
LEU A 214
THR A 215
THR A 216
 ZN  A   1 ( 3.2A)
ZN  A   1 (-3.3A)
None
MLT  A   3 ( 4.2A)
MLT  A   3 ( 4.3A)
MLT  A   3 (-2.8A)
 1.16A 4uovD-3q31A:
28.2		 4uovD-3q31A:
33.20
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4UOV_D_AZMD299_1
(CARBONATE
DEHYDRATASE)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		7 / 11 HIS A 123
HIS A 142
VAL A 154
LEU A 214
THR A 215
THR A 216
TRP A 225
 ZN  A   1 ( 3.2A)
ZN  A   1 ( 3.2A)
MLT  A   3 (-4.6A)
MLT  A   3 ( 4.2A)
MLT  A   3 ( 4.3A)
MLT  A   3 (-2.8A)
MLT  A   3 (-4.9A)
 1.42A 4uovD-3q31A:
28.2		 4uovD-3q31A:
33.20
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4UOV_D_AZMD299_1
(CARBONATE
DEHYDRATASE)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		6 / 11 HIS A 125
GLU A 129
VAL A 154
LEU A 214
THR A 215
THR A 216
 ZN  A   1 (-3.3A)
ZN  A   1 ( 4.7A)
MLT  A   3 (-4.6A)
MLT  A   3 ( 4.2A)
MLT  A   3 ( 4.3A)
MLT  A   3 (-2.8A)
 0.96A 4uovD-3q31A:
28.2		 4uovD-3q31A:
33.20
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4UOV_E_AZME299_1
(CARBONATE
DEHYDRATASE)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		7 / 11 GLN A 102
HIS A 123
HIS A 125
GLU A 129
HIS A 142
THR A 215
THR A 216
 None
ZN  A   1 ( 3.2A)
ZN  A   1 (-3.3A)
ZN  A   1 ( 4.7A)
ZN  A   1 ( 3.2A)
MLT  A   3 ( 4.3A)
MLT  A   3 (-2.8A)
 1.04A 4uovE-3q31A:
28.2		 4uovE-3q31A:
33.20
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4UOV_E_AZME299_1
(CARBONATE
DEHYDRATASE)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		5 / 11 GLN A 102
HIS A 125
VAL A 144
THR A 215
THR A 216
 None
ZN  A   1 (-3.3A)
None
MLT  A   3 ( 4.3A)
MLT  A   3 (-2.8A)
 1.10A 4uovE-3q31A:
28.2		 4uovE-3q31A:
33.20
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4UOV_E_AZME299_1
(CARBONATE
DEHYDRATASE)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		5 / 11 GLN A 121
HIS A 123
GLU A 140
VAL A 144
THR A 215
 MLT  A   3 (-3.9A)
ZN  A   1 ( 3.2A)
None
None
MLT  A   3 ( 4.3A)
 1.20A 4uovE-3q31A:
28.2		 4uovE-3q31A:
33.20
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4UOV_E_AZME299_1
(CARBONATE
DEHYDRATASE)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		11 / 11 GLN A 121
HIS A 123
HIS A 125
GLU A 129
HIS A 142
VAL A 144
VAL A 154
LEU A 214
THR A 215
THR A 216
TRP A 225
 MLT  A   3 (-3.9A)
ZN  A   1 ( 3.2A)
ZN  A   1 (-3.3A)
ZN  A   1 ( 4.7A)
ZN  A   1 ( 3.2A)
None
MLT  A   3 (-4.6A)
MLT  A   3 ( 4.2A)
MLT  A   3 ( 4.3A)
MLT  A   3 (-2.8A)
MLT  A   3 (-4.9A)
 0.34A 4uovE-3q31A:
28.2		 4uovE-3q31A:
33.20
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4UOV_E_AZME299_1
(CARBONATE
DEHYDRATASE)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		7 / 11 HIS A 123
HIS A 142
VAL A 154
LEU A 214
THR A 215
THR A 216
TRP A 225
 ZN  A   1 ( 3.2A)
ZN  A   1 ( 3.2A)
MLT  A   3 (-4.6A)
MLT  A   3 ( 4.2A)
MLT  A   3 ( 4.3A)
MLT  A   3 (-2.8A)
MLT  A   3 (-4.9A)
 1.42A 4uovE-3q31A:
28.2		 4uovE-3q31A:
33.20
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4UOV_E_AZME299_1
(CARBONATE
DEHYDRATASE)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		6 / 11 HIS A 125
GLU A 129
VAL A 154
LEU A 214
THR A 215
THR A 216
 ZN  A   1 (-3.3A)
ZN  A   1 ( 4.7A)
MLT  A   3 (-4.6A)
MLT  A   3 ( 4.2A)
MLT  A   3 ( 4.3A)
MLT  A   3 (-2.8A)
 0.97A 4uovE-3q31A:
28.2		 4uovE-3q31A:
33.20
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4UOV_F_AZMF299_1
(CARBONATE
DEHYDRATASE)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		7 / 11 GLN A 102
HIS A 123
HIS A 125
GLU A 129
HIS A 142
THR A 215
THR A 216
 None
ZN  A   1 ( 3.2A)
ZN  A   1 (-3.3A)
ZN  A   1 ( 4.7A)
ZN  A   1 ( 3.2A)
MLT  A   3 ( 4.3A)
MLT  A   3 (-2.8A)
 1.04A 4uovF-3q31A:
28.2		 4uovF-3q31A:
33.20
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4UOV_F_AZMF299_1
(CARBONATE
DEHYDRATASE)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		6 / 11 GLN A 102
HIS A 125
GLU A 129
VAL A 144
THR A 215
THR A 216
 None
ZN  A   1 (-3.3A)
ZN  A   1 ( 4.7A)
None
MLT  A   3 ( 4.3A)
MLT  A   3 (-2.8A)
 1.14A 4uovF-3q31A:
28.2		 4uovF-3q31A:
33.20
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4UOV_F_AZMF299_1
(CARBONATE
DEHYDRATASE)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		7 / 11 GLN A 121
HIS A 123
GLU A 140
HIS A 142
VAL A 144
VAL A 154
TRP A 225
 MLT  A   3 (-3.9A)
ZN  A   1 ( 3.2A)
None
ZN  A   1 ( 3.2A)
None
MLT  A   3 (-4.6A)
MLT  A   3 (-4.9A)
 1.49A 4uovF-3q31A:
28.2		 4uovF-3q31A:
33.20
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4UOV_F_AZMF299_1
(CARBONATE
DEHYDRATASE)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		5 / 11 GLN A 121
HIS A 123
GLU A 140
VAL A 144
THR A 215
 MLT  A   3 (-3.9A)
ZN  A   1 ( 3.2A)
None
None
MLT  A   3 ( 4.3A)
 1.19A 4uovF-3q31A:
28.2		 4uovF-3q31A:
33.20
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4UOV_F_AZMF299_1
(CARBONATE
DEHYDRATASE)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		11 / 11 GLN A 121
HIS A 123
HIS A 125
GLU A 129
HIS A 142
VAL A 144
VAL A 154
LEU A 214
THR A 215
THR A 216
TRP A 225
 MLT  A   3 (-3.9A)
ZN  A   1 ( 3.2A)
ZN  A   1 (-3.3A)
ZN  A   1 ( 4.7A)
ZN  A   1 ( 3.2A)
None
MLT  A   3 (-4.6A)
MLT  A   3 ( 4.2A)
MLT  A   3 ( 4.3A)
MLT  A   3 (-2.8A)
MLT  A   3 (-4.9A)
 0.34A 4uovF-3q31A:
28.2		 4uovF-3q31A:
33.20
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4UOV_F_AZMF299_1
(CARBONATE
DEHYDRATASE)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		7 / 11 HIS A 123
HIS A 142
VAL A 154
LEU A 214
THR A 215
THR A 216
TRP A 225
 ZN  A   1 ( 3.2A)
ZN  A   1 ( 3.2A)
MLT  A   3 (-4.6A)
MLT  A   3 ( 4.2A)
MLT  A   3 ( 4.3A)
MLT  A   3 (-2.8A)
MLT  A   3 (-4.9A)
 1.41A 4uovF-3q31A:
28.2		 4uovF-3q31A:
33.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UUU_B_SAMB1548_0
(CYSTATHIONINE
BETA-SYNTHASE)		 5kvu ISOCITRATE
DEHYDROGENASE
(Mycobacterium
tuberculosis) 		5 / 11 SER A  89
ALA A 589
PRO A 590
THR A  13
ILE A  44
 MLT  A 802 ( 3.0A)
NAP  A 801 (-4.0A)
NAP  A 801 (-4.6A)
None
None
 1.28A 4uuuB-5kvuA:
undetectable		 4uuuB-5kvuA:
11.47
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4X5S_A_AZMA302_1
(CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE))		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		8 / 11 GLN A 102
HIS A 123
HIS A 125
GLU A 129
HIS A 142
LEU A 214
THR A 215
THR A 216
 None
ZN  A   1 ( 3.2A)
ZN  A   1 (-3.3A)
ZN  A   1 ( 4.7A)
ZN  A   1 ( 3.2A)
MLT  A   3 ( 4.2A)
MLT  A   3 ( 4.3A)
MLT  A   3 (-2.8A)
 1.07A 4x5sA-3q31A:
28.0		 4x5sA-3q31A:
34.02
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4X5S_A_AZMA302_1
(CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE))		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		7 / 11 GLN A 102
HIS A 123
HIS A 125
VAL A 144
LEU A 214
THR A 215
THR A 216
 None
ZN  A   1 ( 3.2A)
ZN  A   1 (-3.3A)
None
MLT  A   3 ( 4.2A)
MLT  A   3 ( 4.3A)
MLT  A   3 (-2.8A)
 1.34A 4x5sA-3q31A:
28.0		 4x5sA-3q31A:
34.02
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4X5S_A_AZMA302_1
(CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE))		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		6 / 11 GLN A 121
GLU A 140
HIS A 142
VAL A 144
VAL A 154
TRP A 225
 MLT  A   3 (-3.9A)
None
ZN  A   1 ( 3.2A)
None
MLT  A   3 (-4.6A)
MLT  A   3 (-4.9A)
 1.49A 4x5sA-3q31A:
28.0		 4x5sA-3q31A:
34.02
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4X5S_A_AZMA302_1
(CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE))		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		11 / 11 GLN A 121
HIS A 123
HIS A 125
GLU A 129
HIS A 142
VAL A 144
VAL A 154
LEU A 214
THR A 215
THR A 216
TRP A 225
 MLT  A   3 (-3.9A)
ZN  A   1 ( 3.2A)
ZN  A   1 (-3.3A)
ZN  A   1 ( 4.7A)
ZN  A   1 ( 3.2A)
None
MLT  A   3 (-4.6A)
MLT  A   3 ( 4.2A)
MLT  A   3 ( 4.3A)
MLT  A   3 (-2.8A)
MLT  A   3 (-4.9A)
 0.34A 4x5sA-3q31A:
28.0		 4x5sA-3q31A:
34.02
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4X5S_A_AZMA302_1
(CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE))		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		6 / 11 GLN A 121
HIS A 123
HIS A 125
VAL A 144
LEU A 214
THR A 215
 MLT  A   3 (-3.9A)
ZN  A   1 ( 3.2A)
ZN  A   1 (-3.3A)
None
MLT  A   3 ( 4.2A)
MLT  A   3 ( 4.3A)
 1.49A 4x5sA-3q31A:
28.0		 4x5sA-3q31A:
34.02
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4X5S_A_AZMA302_1
(CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE))		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		7 / 11 HIS A 123
HIS A 142
VAL A 154
LEU A 214
THR A 215
THR A 216
TRP A 225
 ZN  A   1 ( 3.2A)
ZN  A   1 ( 3.2A)
MLT  A   3 (-4.6A)
MLT  A   3 ( 4.2A)
MLT  A   3 ( 4.3A)
MLT  A   3 (-2.8A)
MLT  A   3 (-4.9A)
 1.42A 4x5sA-3q31A:
28.0		 4x5sA-3q31A:
34.02
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4X5S_A_AZMA302_1
(CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE))		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		6 / 11 HIS A 125
GLU A 129
VAL A 154
LEU A 214
THR A 215
THR A 216
 ZN  A   1 (-3.3A)
ZN  A   1 ( 4.7A)
MLT  A   3 (-4.6A)
MLT  A   3 ( 4.2A)
MLT  A   3 ( 4.3A)
MLT  A   3 (-2.8A)
 0.91A 4x5sA-3q31A:
28.0		 4x5sA-3q31A:
34.02
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4X5S_B_AZMB302_1
(CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE))		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		8 / 11 GLN A 102
HIS A 123
HIS A 125
GLU A 129
HIS A 142
LEU A 214
THR A 215
THR A 216
 None
ZN  A   1 ( 3.2A)
ZN  A   1 (-3.3A)
ZN  A   1 ( 4.7A)
ZN  A   1 ( 3.2A)
MLT  A   3 ( 4.2A)
MLT  A   3 ( 4.3A)
MLT  A   3 (-2.8A)
 1.07A 4x5sB-3q31A:
28.0		 4x5sB-3q31A:
34.02
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4X5S_B_AZMB302_1
(CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE))		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		7 / 11 GLN A 102
HIS A 123
HIS A 125
VAL A 144
LEU A 214
THR A 215
THR A 216
 None
ZN  A   1 ( 3.2A)
ZN  A   1 (-3.3A)
None
MLT  A   3 ( 4.2A)
MLT  A   3 ( 4.3A)
MLT  A   3 (-2.8A)
 1.33A 4x5sB-3q31A:
28.0		 4x5sB-3q31A:
34.02
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4X5S_B_AZMB302_1
(CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE))		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		6 / 11 GLN A 121
GLU A 140
HIS A 142
VAL A 144
VAL A 154
TRP A 225
 MLT  A   3 (-3.9A)
None
ZN  A   1 ( 3.2A)
None
MLT  A   3 (-4.6A)
MLT  A   3 (-4.9A)
 1.50A 4x5sB-3q31A:
28.0		 4x5sB-3q31A:
34.02
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4X5S_B_AZMB302_1
(CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE))		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		11 / 11 GLN A 121
HIS A 123
HIS A 125
GLU A 129
HIS A 142
VAL A 144
VAL A 154
LEU A 214
THR A 215
THR A 216
TRP A 225
 MLT  A   3 (-3.9A)
ZN  A   1 ( 3.2A)
ZN  A   1 (-3.3A)
ZN  A   1 ( 4.7A)
ZN  A   1 ( 3.2A)
None
MLT  A   3 (-4.6A)
MLT  A   3 ( 4.2A)
MLT  A   3 ( 4.3A)
MLT  A   3 (-2.8A)
MLT  A   3 (-4.9A)
 0.34A 4x5sB-3q31A:
28.0		 4x5sB-3q31A:
34.02
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4X5S_B_AZMB302_1
(CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE))		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		6 / 11 GLN A 121
HIS A 123
HIS A 125
VAL A 144
LEU A 214
THR A 215
 MLT  A   3 (-3.9A)
ZN  A   1 ( 3.2A)
ZN  A   1 (-3.3A)
None
MLT  A   3 ( 4.2A)
MLT  A   3 ( 4.3A)
 1.49A 4x5sB-3q31A:
28.0		 4x5sB-3q31A:
34.02
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4X5S_B_AZMB302_1
(CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE))		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		7 / 11 HIS A 123
HIS A 142
VAL A 154
LEU A 214
THR A 215
THR A 216
TRP A 225
 ZN  A   1 ( 3.2A)
ZN  A   1 ( 3.2A)
MLT  A   3 (-4.6A)
MLT  A   3 ( 4.2A)
MLT  A   3 ( 4.3A)
MLT  A   3 (-2.8A)
MLT  A   3 (-4.9A)
 1.42A 4x5sB-3q31A:
28.0		 4x5sB-3q31A:
34.02
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4X5S_B_AZMB302_1
(CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE))		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		6 / 11 HIS A 125
GLU A 129
VAL A 154
LEU A 214
THR A 215
THR A 216
 ZN  A   1 (-3.3A)
ZN  A   1 ( 4.7A)
MLT  A   3 (-4.6A)
MLT  A   3 ( 4.2A)
MLT  A   3 ( 4.3A)
MLT  A   3 (-2.8A)
 0.92A 4x5sB-3q31A:
28.0		 4x5sB-3q31A:
34.02
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4XIW_A_AZMA402_1
(CARBONIC ANHYDRASE,
ALPHA TYPE)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		6 / 12 GLN A 102
HIS A 123
HIS A 125
GLU A 129
THR A 215
THR A 216
 None
ZN  A   1 ( 3.2A)
ZN  A   1 (-3.3A)
ZN  A   1 ( 4.7A)
MLT  A   3 ( 4.3A)
MLT  A   3 (-2.8A)
 1.14A 4xiwA-3q31A:
23.2
4xiwH-3q31A:
23.1		 4xiwA-3q31A:
32.09
4xiwH-3q31A:
32.09
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4XIW_A_AZMA402_1
(CARBONIC ANHYDRASE,
ALPHA TYPE)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		6 / 12 GLN A 102
HIS A 125
GLU A 129
VAL A 144
THR A 215
THR A 216
 None
ZN  A   1 (-3.3A)
ZN  A   1 ( 4.7A)
None
MLT  A   3 ( 4.3A)
MLT  A   3 (-2.8A)
 1.12A 4xiwA-3q31A:
23.2
4xiwH-3q31A:
23.1		 4xiwA-3q31A:
32.09
4xiwH-3q31A:
32.09
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4XIW_A_AZMA402_1
(CARBONIC ANHYDRASE,
ALPHA TYPE)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		7 / 12 GLN A 121
HIS A 123
GLU A 140
HIS A 142
VAL A 144
VAL A 154
TRP A 225
 MLT  A   3 (-3.9A)
ZN  A   1 ( 3.2A)
None
ZN  A   1 ( 3.2A)
None
MLT  A   3 (-4.6A)
MLT  A   3 (-4.9A)
 1.43A 4xiwA-3q31A:
23.2
4xiwH-3q31A:
23.1		 4xiwA-3q31A:
32.09
4xiwH-3q31A:
32.09
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4XIW_A_AZMA402_1
(CARBONIC ANHYDRASE,
ALPHA TYPE)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		11 / 12 GLN A 121
HIS A 123
HIS A 125
GLU A 129
HIS A 142
VAL A 144
VAL A 154
LEU A 214
THR A 215
THR A 216
TRP A 225
 MLT  A   3 (-3.9A)
ZN  A   1 ( 3.2A)
ZN  A   1 (-3.3A)
ZN  A   1 ( 4.7A)
ZN  A   1 ( 3.2A)
None
MLT  A   3 (-4.6A)
MLT  A   3 ( 4.2A)
MLT  A   3 ( 4.3A)
MLT  A   3 (-2.8A)
MLT  A   3 (-4.9A)
 0.44A 4xiwA-3q31A:
23.2
4xiwH-3q31A:
23.1		 4xiwA-3q31A:
32.09
4xiwH-3q31A:
32.09
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4XIW_A_AZMA402_1
(CARBONIC ANHYDRASE,
ALPHA TYPE)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		6 / 12 HIS A 123
HIS A 142
VAL A 154
LEU A 214
THR A 216
TRP A 225
 ZN  A   1 ( 3.2A)
ZN  A   1 ( 3.2A)
MLT  A   3 (-4.6A)
MLT  A   3 ( 4.2A)
MLT  A   3 (-2.8A)
MLT  A   3 (-4.9A)
 1.44A 4xiwA-3q31A:
23.2
4xiwH-3q31A:
23.1		 4xiwA-3q31A:
32.09
4xiwH-3q31A:
32.09
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4XIW_B_AZMB402_1
(CARBONIC ANHYDRASE,
ALPHA TYPE)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		7 / 12 GLN A 102
HIS A 123
HIS A 125
GLU A 129
HIS A 142
THR A 215
THR A 216
 None
ZN  A   1 ( 3.2A)
ZN  A   1 (-3.3A)
ZN  A   1 ( 4.7A)
ZN  A   1 ( 3.2A)
MLT  A   3 ( 4.3A)
MLT  A   3 (-2.8A)
 1.12A 4xiwB-3q31A:
23.1
4xiwE-3q31A:
23.2		 4xiwB-3q31A:
32.09
4xiwE-3q31A:
32.09
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4XIW_B_AZMB402_1
(CARBONIC ANHYDRASE,
ALPHA TYPE)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		6 / 12 GLN A 121
HIS A 123
GLU A 140
HIS A 142
VAL A 144
TRP A 225
 MLT  A   3 (-3.9A)
ZN  A   1 ( 3.2A)
None
ZN  A   1 ( 3.2A)
None
MLT  A   3 (-4.9A)
 1.48A 4xiwB-3q31A:
23.1
4xiwE-3q31A:
23.2		 4xiwB-3q31A:
32.09
4xiwE-3q31A:
32.09
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4XIW_B_AZMB402_1
(CARBONIC ANHYDRASE,
ALPHA TYPE)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		5 / 12 GLN A 121
HIS A 123
GLU A 140
VAL A 144
THR A 215
 MLT  A   3 (-3.9A)
ZN  A   1 ( 3.2A)
None
None
MLT  A   3 ( 4.3A)
 1.17A 4xiwB-3q31A:
23.1
4xiwE-3q31A:
23.2		 4xiwB-3q31A:
32.09
4xiwE-3q31A:
32.09
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4XIW_B_AZMB402_1
(CARBONIC ANHYDRASE,
ALPHA TYPE)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		10 / 12 GLN A 121
HIS A 123
HIS A 125
GLU A 129
HIS A 142
VAL A 144
LEU A 214
THR A 215
THR A 216
TRP A 225
 MLT  A   3 (-3.9A)
ZN  A   1 ( 3.2A)
ZN  A   1 (-3.3A)
ZN  A   1 ( 4.7A)
ZN  A   1 ( 3.2A)
None
MLT  A   3 ( 4.2A)
MLT  A   3 ( 4.3A)
MLT  A   3 (-2.8A)
MLT  A   3 (-4.9A)
 0.39A 4xiwB-3q31A:
23.1
4xiwE-3q31A:
23.2		 4xiwB-3q31A:
32.09
4xiwE-3q31A:
32.09
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4XIW_B_AZMB402_1
(CARBONIC ANHYDRASE,
ALPHA TYPE)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		6 / 12 GLN A 121
HIS A 123
HIS A 125
VAL A 144
LEU A 214
THR A 215
 MLT  A   3 (-3.9A)
ZN  A   1 ( 3.2A)
ZN  A   1 (-3.3A)
None
MLT  A   3 ( 4.2A)
MLT  A   3 ( 4.3A)
 1.49A 4xiwB-3q31A:
23.1
4xiwE-3q31A:
23.2		 4xiwB-3q31A:
32.09
4xiwE-3q31A:
32.09
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4XIW_B_AZMB402_1
(CARBONIC ANHYDRASE,
ALPHA TYPE)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		6 / 12 HIS A 125
GLU A 129
VAL A 154
LEU A 214
THR A 215
THR A 216
 ZN  A   1 (-3.3A)
ZN  A   1 ( 4.7A)
MLT  A   3 (-4.6A)
MLT  A   3 ( 4.2A)
MLT  A   3 ( 4.3A)
MLT  A   3 (-2.8A)
 0.88A 4xiwB-3q31A:
23.1
4xiwE-3q31A:
23.2		 4xiwB-3q31A:
32.09
4xiwE-3q31A:
32.09
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4XIW_B_AZMB402_1
(CARBONIC ANHYDRASE,
ALPHA TYPE)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		6 / 12 HIS A 142
HIS A 125
VAL A 154
LEU A 214
THR A 215
THR A 216
 ZN  A   1 ( 3.2A)
ZN  A   1 (-3.3A)
MLT  A   3 (-4.6A)
MLT  A   3 ( 4.2A)
MLT  A   3 ( 4.3A)
MLT  A   3 (-2.8A)
 1.35A 4xiwB-3q31A:
23.1
4xiwE-3q31A:
23.2		 4xiwB-3q31A:
32.09
4xiwE-3q31A:
32.09
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4XIW_C_AZMC402_1
(CARBONIC ANHYDRASE,
ALPHA TYPE)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		6 / 11 GLN A 102
HIS A 123
HIS A 125
GLU A 129
THR A 215
THR A 216
 None
ZN  A   1 ( 3.2A)
ZN  A   1 (-3.3A)
ZN  A   1 ( 4.7A)
MLT  A   3 ( 4.3A)
MLT  A   3 (-2.8A)
 1.18A 4xiwC-3q31A:
23.2		 4xiwC-3q31A:
32.09
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4XIW_C_AZMC402_1
(CARBONIC ANHYDRASE,
ALPHA TYPE)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		6 / 11 GLN A 102
HIS A 125
GLU A 129
VAL A 144
THR A 215
THR A 216
 None
ZN  A   1 (-3.3A)
ZN  A   1 ( 4.7A)
None
MLT  A   3 ( 4.3A)
MLT  A   3 (-2.8A)
 1.23A 4xiwC-3q31A:
23.2		 4xiwC-3q31A:
32.09
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4XIW_C_AZMC402_1
(CARBONIC ANHYDRASE,
ALPHA TYPE)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		7 / 11 GLN A 121
HIS A 123
GLU A 140
HIS A 142
VAL A 144
VAL A 154
TRP A 225
 MLT  A   3 (-3.9A)
ZN  A   1 ( 3.2A)
None
ZN  A   1 ( 3.2A)
None
MLT  A   3 (-4.6A)
MLT  A   3 (-4.9A)
 1.35A 4xiwC-3q31A:
23.2		 4xiwC-3q31A:
32.09
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4XIW_C_AZMC402_1
(CARBONIC ANHYDRASE,
ALPHA TYPE)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		11 / 11 GLN A 121
HIS A 123
HIS A 125
GLU A 129
HIS A 142
VAL A 144
VAL A 154
LEU A 214
THR A 215
THR A 216
TRP A 225
 MLT  A   3 (-3.9A)
ZN  A   1 ( 3.2A)
ZN  A   1 (-3.3A)
ZN  A   1 ( 4.7A)
ZN  A   1 ( 3.2A)
None
MLT  A   3 (-4.6A)
MLT  A   3 ( 4.2A)
MLT  A   3 ( 4.3A)
MLT  A   3 (-2.8A)
MLT  A   3 (-4.9A)
 0.46A 4xiwC-3q31A:
23.2		 4xiwC-3q31A:
32.09
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4XIW_C_AZMC402_1
(CARBONIC ANHYDRASE,
ALPHA TYPE)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		7 / 11 HIS A 123
HIS A 142
VAL A 154
LEU A 214
THR A 215
THR A 216
TRP A 225
 ZN  A   1 ( 3.2A)
ZN  A   1 ( 3.2A)
MLT  A   3 (-4.6A)
MLT  A   3 ( 4.2A)
MLT  A   3 ( 4.3A)
MLT  A   3 (-2.8A)
MLT  A   3 (-4.9A)
 1.41A 4xiwC-3q31A:
23.2		 4xiwC-3q31A:
32.09
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4XIW_C_AZMC402_1
(CARBONIC ANHYDRASE,
ALPHA TYPE)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		6 / 11 HIS A 142
HIS A 125
VAL A 154
LEU A 214
THR A 215
THR A 216
 ZN  A   1 ( 3.2A)
ZN  A   1 (-3.3A)
MLT  A   3 (-4.6A)
MLT  A   3 ( 4.2A)
MLT  A   3 ( 4.3A)
MLT  A   3 (-2.8A)
 1.35A 4xiwC-3q31A:
23.2		 4xiwC-3q31A:
32.09
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4XIW_D_AZMD402_1
(CARBONIC ANHYDRASE,
ALPHA TYPE)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		6 / 11 GLN A 102
HIS A 123
HIS A 125
GLU A 129
THR A 215
THR A 216
 None
ZN  A   1 ( 3.2A)
ZN  A   1 (-3.3A)
ZN  A   1 ( 4.7A)
MLT  A   3 ( 4.3A)
MLT  A   3 (-2.8A)
 1.15A 4xiwD-3q31A:
23.2		 4xiwD-3q31A:
32.09
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4XIW_D_AZMD402_1
(CARBONIC ANHYDRASE,
ALPHA TYPE)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		6 / 11 GLN A 102
HIS A 125
GLU A 129
VAL A 144
THR A 215
THR A 216
 None
ZN  A   1 (-3.3A)
ZN  A   1 ( 4.7A)
None
MLT  A   3 ( 4.3A)
MLT  A   3 (-2.8A)
 1.15A 4xiwD-3q31A:
23.2		 4xiwD-3q31A:
32.09
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4XIW_D_AZMD402_1
(CARBONIC ANHYDRASE,
ALPHA TYPE)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		7 / 11 GLN A 121
HIS A 123
GLU A 140
HIS A 142
VAL A 144
VAL A 154
TRP A 225
 MLT  A   3 (-3.9A)
ZN  A   1 ( 3.2A)
None
ZN  A   1 ( 3.2A)
None
MLT  A   3 (-4.6A)
MLT  A   3 (-4.9A)
 1.40A 4xiwD-3q31A:
23.2		 4xiwD-3q31A:
32.09
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4XIW_D_AZMD402_1
(CARBONIC ANHYDRASE,
ALPHA TYPE)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		11 / 11 GLN A 121
HIS A 123
HIS A 125
GLU A 129
HIS A 142
VAL A 144
VAL A 154
LEU A 214
THR A 215
THR A 216
TRP A 225
 MLT  A   3 (-3.9A)
ZN  A   1 ( 3.2A)
ZN  A   1 (-3.3A)
ZN  A   1 ( 4.7A)
ZN  A   1 ( 3.2A)
None
MLT  A   3 (-4.6A)
MLT  A   3 ( 4.2A)
MLT  A   3 ( 4.3A)
MLT  A   3 (-2.8A)
MLT  A   3 (-4.9A)
 0.40A 4xiwD-3q31A:
23.2		 4xiwD-3q31A:
32.09
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4XIW_D_AZMD402_1
(CARBONIC ANHYDRASE,
ALPHA TYPE)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		6 / 11 GLN A 121
HIS A 123
HIS A 125
VAL A 144
LEU A 214
THR A 215
 MLT  A   3 (-3.9A)
ZN  A   1 ( 3.2A)
ZN  A   1 (-3.3A)
None
MLT  A   3 ( 4.2A)
MLT  A   3 ( 4.3A)
 1.39A 4xiwD-3q31A:
23.2		 4xiwD-3q31A:
32.09
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4XIW_D_AZMD402_1
(CARBONIC ANHYDRASE,
ALPHA TYPE)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		6 / 11 HIS A 123
HIS A 142
VAL A 154
LEU A 214
THR A 216
TRP A 225
 ZN  A   1 ( 3.2A)
ZN  A   1 ( 3.2A)
MLT  A   3 (-4.6A)
MLT  A   3 ( 4.2A)
MLT  A   3 (-2.8A)
MLT  A   3 (-4.9A)
 1.49A 4xiwD-3q31A:
23.2		 4xiwD-3q31A:
32.09
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4XIW_E_AZME402_1
(CARBONIC ANHYDRASE,
ALPHA TYPE)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		6 / 11 GLN A 102
HIS A 123
HIS A 125
GLU A 129
THR A 215
THR A 216
 None
ZN  A   1 ( 3.2A)
ZN  A   1 (-3.3A)
ZN  A   1 ( 4.7A)
MLT  A   3 ( 4.3A)
MLT  A   3 (-2.8A)
 1.14A 4xiwE-3q31A:
23.2		 4xiwE-3q31A:
32.09
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4XIW_E_AZME402_1
(CARBONIC ANHYDRASE,
ALPHA TYPE)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		6 / 11 GLN A 102
HIS A 123
HIS A 125
GLU A 129
VAL A 144
THR A 216
 None
ZN  A   1 ( 3.2A)
ZN  A   1 (-3.3A)
ZN  A   1 ( 4.7A)
None
MLT  A   3 (-2.8A)
 1.28A 4xiwE-3q31A:
23.2		 4xiwE-3q31A:
32.09
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4XIW_E_AZME402_1
(CARBONIC ANHYDRASE,
ALPHA TYPE)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		7 / 11 GLN A 121
HIS A 123
GLU A 140
HIS A 142
VAL A 144
VAL A 154
TRP A 225
 MLT  A   3 (-3.9A)
ZN  A   1 ( 3.2A)
None
ZN  A   1 ( 3.2A)
None
MLT  A   3 (-4.6A)
MLT  A   3 (-4.9A)
 1.43A 4xiwE-3q31A:
23.2		 4xiwE-3q31A:
32.09
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4XIW_E_AZME402_1
(CARBONIC ANHYDRASE,
ALPHA TYPE)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		11 / 11 GLN A 121
HIS A 123
HIS A 125
GLU A 129
HIS A 142
VAL A 144
VAL A 154
LEU A 214
THR A 215
THR A 216
TRP A 225
 MLT  A   3 (-3.9A)
ZN  A   1 ( 3.2A)
ZN  A   1 (-3.3A)
ZN  A   1 ( 4.7A)
ZN  A   1 ( 3.2A)
None
MLT  A   3 (-4.6A)
MLT  A   3 ( 4.2A)
MLT  A   3 ( 4.3A)
MLT  A   3 (-2.8A)
MLT  A   3 (-4.9A)
 0.37A 4xiwE-3q31A:
23.2		 4xiwE-3q31A:
32.09
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4XIW_E_AZME402_1
(CARBONIC ANHYDRASE,
ALPHA TYPE)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		6 / 11 HIS A 123
HIS A 125
GLU A 129
VAL A 144
LEU A 214
THR A 216
 ZN  A   1 ( 3.2A)
ZN  A   1 (-3.3A)
ZN  A   1 ( 4.7A)
None
MLT  A   3 ( 4.2A)
MLT  A   3 (-2.8A)
 1.26A 4xiwE-3q31A:
23.2		 4xiwE-3q31A:
32.09
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4XIW_E_AZME402_1
(CARBONIC ANHYDRASE,
ALPHA TYPE)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		7 / 11 HIS A 123
HIS A 142
VAL A 154
LEU A 214
THR A 215
THR A 216
TRP A 225
 ZN  A   1 ( 3.2A)
ZN  A   1 ( 3.2A)
MLT  A   3 (-4.6A)
MLT  A   3 ( 4.2A)
MLT  A   3 ( 4.3A)
MLT  A   3 (-2.8A)
MLT  A   3 (-4.9A)
 1.44A 4xiwE-3q31A:
23.2		 4xiwE-3q31A:
32.09
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4XIW_E_AZME402_1
(CARBONIC ANHYDRASE,
ALPHA TYPE)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		6 / 11 HIS A 125
GLU A 129
VAL A 154
LEU A 214
THR A 215
THR A 216
 ZN  A   1 (-3.3A)
ZN  A   1 ( 4.7A)
MLT  A   3 (-4.6A)
MLT  A   3 ( 4.2A)
MLT  A   3 ( 4.3A)
MLT  A   3 (-2.8A)
 0.91A 4xiwE-3q31A:
23.2		 4xiwE-3q31A:
32.09
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4XIW_F_AZMF402_1
(CARBONIC ANHYDRASE,
ALPHA TYPE)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		7 / 11 GLN A 102
HIS A 123
HIS A 125
GLU A 129
HIS A 142
THR A 215
THR A 216
 None
ZN  A   1 ( 3.2A)
ZN  A   1 (-3.3A)
ZN  A   1 ( 4.7A)
ZN  A   1 ( 3.2A)
MLT  A   3 ( 4.3A)
MLT  A   3 (-2.8A)
 1.08A 4xiwF-3q31A:
23.2		 4xiwF-3q31A:
32.09
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4XIW_F_AZMF402_1
(CARBONIC ANHYDRASE,
ALPHA TYPE)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		7 / 11 GLN A 121
HIS A 123
GLU A 140
HIS A 142
VAL A 144
VAL A 154
TRP A 225
 MLT  A   3 (-3.9A)
ZN  A   1 ( 3.2A)
None
ZN  A   1 ( 3.2A)
None
MLT  A   3 (-4.6A)
MLT  A   3 (-4.9A)
 1.48A 4xiwF-3q31A:
23.2		 4xiwF-3q31A:
32.09
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4XIW_F_AZMF402_1
(CARBONIC ANHYDRASE,
ALPHA TYPE)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		11 / 11 GLN A 121
HIS A 123
HIS A 125
GLU A 129
HIS A 142
VAL A 144
VAL A 154
LEU A 214
THR A 215
THR A 216
TRP A 225
 MLT  A   3 (-3.9A)
ZN  A   1 ( 3.2A)
ZN  A   1 (-3.3A)
ZN  A   1 ( 4.7A)
ZN  A   1 ( 3.2A)
None
MLT  A   3 (-4.6A)
MLT  A   3 ( 4.2A)
MLT  A   3 ( 4.3A)
MLT  A   3 (-2.8A)
MLT  A   3 (-4.9A)
 0.38A 4xiwF-3q31A:
23.2		 4xiwF-3q31A:
32.09
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4XIW_F_AZMF402_1
(CARBONIC ANHYDRASE,
ALPHA TYPE)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		6 / 11 GLN A 121
HIS A 123
HIS A 125
VAL A 144
LEU A 214
THR A 215
 MLT  A   3 (-3.9A)
ZN  A   1 ( 3.2A)
ZN  A   1 (-3.3A)
None
MLT  A   3 ( 4.2A)
MLT  A   3 ( 4.3A)
 1.40A 4xiwF-3q31A:
23.2		 4xiwF-3q31A:
32.09
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4XIW_F_AZMF402_1
(CARBONIC ANHYDRASE,
ALPHA TYPE)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		7 / 11 HIS A 123
HIS A 142
VAL A 154
LEU A 214
THR A 215
THR A 216
TRP A 225
 ZN  A   1 ( 3.2A)
ZN  A   1 ( 3.2A)
MLT  A   3 (-4.6A)
MLT  A   3 ( 4.2A)
MLT  A   3 ( 4.3A)
MLT  A   3 (-2.8A)
MLT  A   3 (-4.9A)
 1.37A 4xiwF-3q31A:
23.2		 4xiwF-3q31A:
32.09
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4XIW_F_AZMF402_1
(CARBONIC ANHYDRASE,
ALPHA TYPE)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		6 / 11 HIS A 125
GLU A 129
VAL A 154
LEU A 214
THR A 215
THR A 216
 ZN  A   1 (-3.3A)
ZN  A   1 ( 4.7A)
MLT  A   3 (-4.6A)
MLT  A   3 ( 4.2A)
MLT  A   3 ( 4.3A)
MLT  A   3 (-2.8A)
 0.91A 4xiwF-3q31A:
23.2		 4xiwF-3q31A:
32.09
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4XIW_G_AZMG402_1
(CARBONIC ANHYDRASE,
ALPHA TYPE)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		6 / 12 GLN A 102
HIS A 123
HIS A 125
GLU A 129
THR A 215
THR A 216
 None
ZN  A   1 ( 3.2A)
ZN  A   1 (-3.3A)
ZN  A   1 ( 4.7A)
MLT  A   3 ( 4.3A)
MLT  A   3 (-2.8A)
 1.19A 4xiwG-3q31A:
23.2		 4xiwG-3q31A:
32.09
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4XIW_G_AZMG402_1
(CARBONIC ANHYDRASE,
ALPHA TYPE)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		6 / 12 GLN A 102
HIS A 123
HIS A 125
VAL A 144
THR A 215
THR A 216
 None
ZN  A   1 ( 3.2A)
ZN  A   1 (-3.3A)
None
MLT  A   3 ( 4.3A)
MLT  A   3 (-2.8A)
 1.19A 4xiwG-3q31A:
23.2		 4xiwG-3q31A:
32.09
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4XIW_G_AZMG402_1
(CARBONIC ANHYDRASE,
ALPHA TYPE)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		11 / 12 GLN A 121
HIS A 123
HIS A 125
GLU A 129
HIS A 142
VAL A 144
VAL A 154
LEU A 214
THR A 215
THR A 216
TRP A 225
 MLT  A   3 (-3.9A)
ZN  A   1 ( 3.2A)
ZN  A   1 (-3.3A)
ZN  A   1 ( 4.7A)
ZN  A   1 ( 3.2A)
None
MLT  A   3 (-4.6A)
MLT  A   3 ( 4.2A)
MLT  A   3 ( 4.3A)
MLT  A   3 (-2.8A)
MLT  A   3 (-4.9A)
 0.48A 4xiwG-3q31A:
23.2		 4xiwG-3q31A:
32.09
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4XIW_G_AZMG402_1
(CARBONIC ANHYDRASE,
ALPHA TYPE)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		6 / 12 GLN A 121
HIS A 123
HIS A 125
VAL A 144
LEU A 214
THR A 215
 MLT  A   3 (-3.9A)
ZN  A   1 ( 3.2A)
ZN  A   1 (-3.3A)
None
MLT  A   3 ( 4.2A)
MLT  A   3 ( 4.3A)
 1.40A 4xiwG-3q31A:
23.2		 4xiwG-3q31A:
32.09
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4XIW_G_AZMG402_1
(CARBONIC ANHYDRASE,
ALPHA TYPE)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		6 / 12 HIS A 123
HIS A 125
VAL A 144
LEU A 214
THR A 215
THR A 216
 ZN  A   1 ( 3.2A)
ZN  A   1 (-3.3A)
None
MLT  A   3 ( 4.2A)
MLT  A   3 ( 4.3A)
MLT  A   3 (-2.8A)
 1.22A 4xiwG-3q31A:
23.2		 4xiwG-3q31A:
32.09
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4XIW_G_AZMG402_1
(CARBONIC ANHYDRASE,
ALPHA TYPE)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		6 / 12 HIS A 123
HIS A 142
VAL A 154
LEU A 214
THR A 216
TRP A 225
 ZN  A   1 ( 3.2A)
ZN  A   1 ( 3.2A)
MLT  A   3 (-4.6A)
MLT  A   3 ( 4.2A)
MLT  A   3 (-2.8A)
MLT  A   3 (-4.9A)
 1.46A 4xiwG-3q31A:
23.2		 4xiwG-3q31A:
32.09
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4XIW_G_AZMG402_1
(CARBONIC ANHYDRASE,
ALPHA TYPE)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		6 / 12 HIS A 125
GLU A 129
VAL A 154
LEU A 214
THR A 215
THR A 216
 ZN  A   1 (-3.3A)
ZN  A   1 ( 4.7A)
MLT  A   3 (-4.6A)
MLT  A   3 ( 4.2A)
MLT  A   3 ( 4.3A)
MLT  A   3 (-2.8A)
 0.97A 4xiwG-3q31A:
23.2		 4xiwG-3q31A:
32.09
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4XIW_H_AZMH402_1
(CARBONIC ANHYDRASE,
ALPHA TYPE)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		6 / 11 GLN A 102
HIS A 123
HIS A 125
GLU A 129
THR A 215
THR A 216
 None
ZN  A   1 ( 3.2A)
ZN  A   1 (-3.3A)
ZN  A   1 ( 4.7A)
MLT  A   3 ( 4.3A)
MLT  A   3 (-2.8A)
 1.19A 4xiwH-3q31A:
23.1		 4xiwH-3q31A:
32.09
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4XIW_H_AZMH402_1
(CARBONIC ANHYDRASE,
ALPHA TYPE)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		6 / 11 GLN A 102
HIS A 125
GLU A 129
VAL A 144
THR A 215
THR A 216
 None
ZN  A   1 (-3.3A)
ZN  A   1 ( 4.7A)
None
MLT  A   3 ( 4.3A)
MLT  A   3 (-2.8A)
 1.20A 4xiwH-3q31A:
23.1		 4xiwH-3q31A:
32.09
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4XIW_H_AZMH402_1
(CARBONIC ANHYDRASE,
ALPHA TYPE)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		7 / 11 GLN A 121
HIS A 123
GLU A 140
HIS A 142
VAL A 144
VAL A 154
TRP A 225
 MLT  A   3 (-3.9A)
ZN  A   1 ( 3.2A)
None
ZN  A   1 ( 3.2A)
None
MLT  A   3 (-4.6A)
MLT  A   3 (-4.9A)
 1.42A 4xiwH-3q31A:
23.1		 4xiwH-3q31A:
32.09
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4XIW_H_AZMH402_1
(CARBONIC ANHYDRASE,
ALPHA TYPE)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		11 / 11 GLN A 121
HIS A 123
HIS A 125
GLU A 129
HIS A 142
VAL A 144
VAL A 154
LEU A 214
THR A 215
THR A 216
TRP A 225
 MLT  A   3 (-3.9A)
ZN  A   1 ( 3.2A)
ZN  A   1 (-3.3A)
ZN  A   1 ( 4.7A)
ZN  A   1 ( 3.2A)
None
MLT  A   3 (-4.6A)
MLT  A   3 ( 4.2A)
MLT  A   3 ( 4.3A)
MLT  A   3 (-2.8A)
MLT  A   3 (-4.9A)
 0.42A 4xiwH-3q31A:
23.1		 4xiwH-3q31A:
32.09
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4XIW_H_AZMH402_1
(CARBONIC ANHYDRASE,
ALPHA TYPE)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		7 / 11 HIS A 123
HIS A 142
VAL A 154
LEU A 214
THR A 215
THR A 216
TRP A 225
 ZN  A   1 ( 3.2A)
ZN  A   1 ( 3.2A)
MLT  A   3 (-4.6A)
MLT  A   3 ( 4.2A)
MLT  A   3 ( 4.3A)
MLT  A   3 (-2.8A)
MLT  A   3 (-4.9A)
 1.43A 4xiwH-3q31A:
23.1		 4xiwH-3q31A:
32.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YGF_A_AZMA303_1
(ALPHA-CARBONIC
ANHYDRASE)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		6 / 11 HIS A 123
HIS A 125
HIS A 142
VAL A 144
LEU A 214
THR A 215
 ZN  A   1 ( 3.2A)
ZN  A   1 (-3.3A)
ZN  A   1 ( 3.2A)
None
MLT  A   3 ( 4.2A)
MLT  A   3 ( 4.3A)
 1.16A 4ygfA-3q31A:
26.3		 4ygfA-3q31A:
29.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YGF_A_AZMA303_1
(ALPHA-CARBONIC
ANHYDRASE)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		8 / 11 HIS A 123
HIS A 125
HIS A 142
VAL A 144
VAL A 154
LEU A 214
THR A 215
TRP A 225
 ZN  A   1 ( 3.2A)
ZN  A   1 (-3.3A)
ZN  A   1 ( 3.2A)
None
MLT  A   3 (-4.6A)
MLT  A   3 ( 4.2A)
MLT  A   3 ( 4.3A)
MLT  A   3 (-4.9A)
 0.47A 4ygfA-3q31A:
26.3		 4ygfA-3q31A:
29.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YGF_B_AZMB303_1
(ALPHA-CARBONIC
ANHYDRASE)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		9 / 11 HIS A 123
HIS A 125
GLU A 129
HIS A 142
VAL A 144
VAL A 154
LEU A 214
THR A 215
TRP A 225
 ZN  A   1 ( 3.2A)
ZN  A   1 (-3.3A)
ZN  A   1 ( 4.7A)
ZN  A   1 ( 3.2A)
None
MLT  A   3 (-4.6A)
MLT  A   3 ( 4.2A)
MLT  A   3 ( 4.3A)
MLT  A   3 (-4.9A)
 0.46A 4ygfB-3q31A:
26.0		 4ygfB-3q31A:
29.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YGF_B_AZMB303_1
(ALPHA-CARBONIC
ANHYDRASE)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		6 / 11 HIS A 123
HIS A 142
VAL A 154
LEU A 214
THR A 215
TRP A 225
 ZN  A   1 ( 3.2A)
ZN  A   1 ( 3.2A)
MLT  A   3 (-4.6A)
MLT  A   3 ( 4.2A)
MLT  A   3 ( 4.3A)
MLT  A   3 (-4.9A)
 1.39A 4ygfB-3q31A:
26.0		 4ygfB-3q31A:
29.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YGF_B_AZMB303_1
(ALPHA-CARBONIC
ANHYDRASE)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		6 / 11 HIS A 125
GLU A 129
HIS A 142
VAL A 144
LEU A 214
THR A 215
 ZN  A   1 (-3.3A)
ZN  A   1 ( 4.7A)
ZN  A   1 ( 3.2A)
None
MLT  A   3 ( 4.2A)
MLT  A   3 ( 4.3A)
 1.00A 4ygfB-3q31A:
26.0		 4ygfB-3q31A:
29.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YGF_B_AZMB303_1
(ALPHA-CARBONIC
ANHYDRASE)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		5 / 11 HIS A 125
HIS A 123
VAL A 144
LEU A 214
THR A 215
 ZN  A   1 (-3.3A)
ZN  A   1 ( 3.2A)
None
MLT  A   3 ( 4.2A)
MLT  A   3 ( 4.3A)
 1.45A 4ygfB-3q31A:
26.0		 4ygfB-3q31A:
29.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YGF_C_AZMC303_1
(ALPHA-CARBONIC
ANHYDRASE)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		6 / 11 HIS A 123
HIS A 125
HIS A 142
VAL A 144
LEU A 214
THR A 215
 ZN  A   1 ( 3.2A)
ZN  A   1 (-3.3A)
ZN  A   1 ( 3.2A)
None
MLT  A   3 ( 4.2A)
MLT  A   3 ( 4.3A)
 1.14A 4ygfC-3q31A:
18.8		 4ygfC-3q31A:
29.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YGF_C_AZMC303_1
(ALPHA-CARBONIC
ANHYDRASE)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		8 / 11 HIS A 123
HIS A 125
HIS A 142
VAL A 144
VAL A 154
LEU A 214
THR A 215
TRP A 225
 ZN  A   1 ( 3.2A)
ZN  A   1 (-3.3A)
ZN  A   1 ( 3.2A)
None
MLT  A   3 (-4.6A)
MLT  A   3 ( 4.2A)
MLT  A   3 ( 4.3A)
MLT  A   3 (-4.9A)
 0.42A 4ygfC-3q31A:
18.8		 4ygfC-3q31A:
29.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YGF_C_AZMC303_1
(ALPHA-CARBONIC
ANHYDRASE)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		5 / 11 HIS A 123
HIS A 142
VAL A 154
LEU A 214
TRP A 225
 ZN  A   1 ( 3.2A)
ZN  A   1 ( 3.2A)
MLT  A   3 (-4.6A)
MLT  A   3 ( 4.2A)
MLT  A   3 (-4.9A)
 1.48A 4ygfC-3q31A:
18.8		 4ygfC-3q31A:
29.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YGF_C_AZMC303_1
(ALPHA-CARBONIC
ANHYDRASE)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		5 / 11 HIS A 125
HIS A 123
VAL A 144
LEU A 214
THR A 215
 ZN  A   1 (-3.3A)
ZN  A   1 ( 3.2A)
None
MLT  A   3 ( 4.2A)
MLT  A   3 ( 4.3A)
 1.41A 4ygfC-3q31A:
18.8		 4ygfC-3q31A:
29.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YGF_C_AZMC303_1
(ALPHA-CARBONIC
ANHYDRASE)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		5 / 11 HIS A 142
HIS A 125
VAL A 154
LEU A 214
THR A 215
 ZN  A   1 ( 3.2A)
ZN  A   1 (-3.3A)
MLT  A   3 (-4.6A)
MLT  A   3 ( 4.2A)
MLT  A   3 ( 4.3A)
 1.34A 4ygfC-3q31A:
18.8		 4ygfC-3q31A:
29.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YGF_D_AZMD303_1
(ALPHA-CARBONIC
ANHYDRASE)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		9 / 11 HIS A 123
HIS A 125
GLU A 129
HIS A 142
VAL A 144
VAL A 154
LEU A 214
THR A 215
TRP A 225
 ZN  A   1 ( 3.2A)
ZN  A   1 (-3.3A)
ZN  A   1 ( 4.7A)
ZN  A   1 ( 3.2A)
None
MLT  A   3 (-4.6A)
MLT  A   3 ( 4.2A)
MLT  A   3 ( 4.3A)
MLT  A   3 (-4.9A)
 0.42A 4ygfD-3q31A:
25.2		 4ygfD-3q31A:
29.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YGF_D_AZMD303_1
(ALPHA-CARBONIC
ANHYDRASE)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		6 / 11 HIS A 125
GLU A 129
HIS A 142
VAL A 144
LEU A 214
THR A 215
 ZN  A   1 (-3.3A)
ZN  A   1 ( 4.7A)
ZN  A   1 ( 3.2A)
None
MLT  A   3 ( 4.2A)
MLT  A   3 ( 4.3A)
 1.06A 4ygfD-3q31A:
25.2		 4ygfD-3q31A:
29.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YGF_D_AZMD303_1
(ALPHA-CARBONIC
ANHYDRASE)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		5 / 11 HIS A 142
HIS A 125
VAL A 154
LEU A 214
THR A 215
 ZN  A   1 ( 3.2A)
ZN  A   1 (-3.3A)
MLT  A   3 (-4.6A)
MLT  A   3 ( 4.2A)
MLT  A   3 ( 4.3A)
 1.31A 4ygfD-3q31A:
25.2		 4ygfD-3q31A:
29.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YGF_E_AZME303_1
(ALPHA-CARBONIC
ANHYDRASE)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		9 / 12 HIS A 123
HIS A 125
GLU A 129
HIS A 142
VAL A 144
VAL A 154
LEU A 214
THR A 215
TRP A 225
 ZN  A   1 ( 3.2A)
ZN  A   1 (-3.3A)
ZN  A   1 ( 4.7A)
ZN  A   1 ( 3.2A)
None
MLT  A   3 (-4.6A)
MLT  A   3 ( 4.2A)
MLT  A   3 ( 4.3A)
MLT  A   3 (-4.9A)
 0.44A 4ygfE-3q31A:
26.3		 4ygfE-3q31A:
29.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YGF_E_AZME303_1
(ALPHA-CARBONIC
ANHYDRASE)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		5 / 12 HIS A 123
HIS A 142
VAL A 154
LEU A 214
TRP A 225
 ZN  A   1 ( 3.2A)
ZN  A   1 ( 3.2A)
MLT  A   3 (-4.6A)
MLT  A   3 ( 4.2A)
MLT  A   3 (-4.9A)
 1.43A 4ygfE-3q31A:
26.3		 4ygfE-3q31A:
29.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YGF_E_AZME303_1
(ALPHA-CARBONIC
ANHYDRASE)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		6 / 12 HIS A 125
GLU A 129
HIS A 142
VAL A 144
LEU A 214
THR A 215
 ZN  A   1 (-3.3A)
ZN  A   1 ( 4.7A)
ZN  A   1 ( 3.2A)
None
MLT  A   3 ( 4.2A)
MLT  A   3 ( 4.3A)
 0.99A 4ygfE-3q31A:
26.3		 4ygfE-3q31A:
29.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YGF_E_AZME303_1
(ALPHA-CARBONIC
ANHYDRASE)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		5 / 12 HIS A 125
HIS A 123
VAL A 144
LEU A 214
THR A 215
 ZN  A   1 (-3.3A)
ZN  A   1 ( 3.2A)
None
MLT  A   3 ( 4.2A)
MLT  A   3 ( 4.3A)
 1.44A 4ygfE-3q31A:
26.3		 4ygfE-3q31A:
29.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YGF_F_AZMF303_1
(ALPHA-CARBONIC
ANHYDRASE)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		8 / 9 HIS A 123
HIS A 125
HIS A 142
VAL A 144
VAL A 154
LEU A 214
THR A 215
TRP A 225
 ZN  A   1 ( 3.2A)
ZN  A   1 (-3.3A)
ZN  A   1 ( 3.2A)
None
MLT  A   3 (-4.6A)
MLT  A   3 ( 4.2A)
MLT  A   3 ( 4.3A)
MLT  A   3 (-4.9A)
 0.41A 4ygfF-3q31A:
25.9		 4ygfF-3q31A:
29.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YGF_F_AZMF303_1
(ALPHA-CARBONIC
ANHYDRASE)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		5 / 9 HIS A 125
HIS A 123
VAL A 144
LEU A 214
THR A 215
 ZN  A   1 (-3.3A)
ZN  A   1 ( 3.2A)
None
MLT  A   3 ( 4.2A)
MLT  A   3 ( 4.3A)
 1.38A 4ygfF-3q31A:
25.9		 4ygfF-3q31A:
29.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YGF_F_AZMF303_1
(ALPHA-CARBONIC
ANHYDRASE)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		5 / 9 HIS A 125
HIS A 142
VAL A 144
LEU A 214
THR A 215
 ZN  A   1 (-3.3A)
ZN  A   1 ( 3.2A)
None
MLT  A   3 ( 4.2A)
MLT  A   3 ( 4.3A)
 1.08A 4ygfF-3q31A:
25.9		 4ygfF-3q31A:
29.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YGF_F_AZMF303_1
(ALPHA-CARBONIC
ANHYDRASE)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		5 / 9 HIS A 142
HIS A 125
VAL A 154
LEU A 214
THR A 215
 ZN  A   1 ( 3.2A)
ZN  A   1 (-3.3A)
MLT  A   3 (-4.6A)
MLT  A   3 ( 4.2A)
MLT  A   3 ( 4.3A)
 1.37A 4ygfF-3q31A:
25.9		 4ygfF-3q31A:
29.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YGF_G_AZMG303_1
(ALPHA-CARBONIC
ANHYDRASE)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		8 / 12 HIS A 123
HIS A 125
HIS A 142
VAL A 144
VAL A 154
LEU A 214
THR A 215
TRP A 225
 ZN  A   1 ( 3.2A)
ZN  A   1 (-3.3A)
ZN  A   1 ( 3.2A)
None
MLT  A   3 (-4.6A)
MLT  A   3 ( 4.2A)
MLT  A   3 ( 4.3A)
MLT  A   3 (-4.9A)
 0.42A 4ygfG-3q31A:
6.5		 4ygfG-3q31A:
29.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YGF_G_AZMG303_1
(ALPHA-CARBONIC
ANHYDRASE)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		6 / 12 HIS A 123
HIS A 142
VAL A 154
LEU A 214
THR A 215
TRP A 225
 ZN  A   1 ( 3.2A)
ZN  A   1 ( 3.2A)
MLT  A   3 (-4.6A)
MLT  A   3 ( 4.2A)
MLT  A   3 ( 4.3A)
MLT  A   3 (-4.9A)
 1.46A 4ygfG-3q31A:
6.5		 4ygfG-3q31A:
29.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YGF_G_AZMG303_1
(ALPHA-CARBONIC
ANHYDRASE)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		5 / 12 HIS A 125
HIS A 123
VAL A 144
LEU A 214
THR A 215
 ZN  A   1 (-3.3A)
ZN  A   1 ( 3.2A)
None
MLT  A   3 ( 4.2A)
MLT  A   3 ( 4.3A)
 1.42A 4ygfG-3q31A:
6.5		 4ygfG-3q31A:
29.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YGF_G_AZMG303_1
(ALPHA-CARBONIC
ANHYDRASE)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		5 / 12 HIS A 125
HIS A 142
VAL A 144
LEU A 214
THR A 215
 ZN  A   1 (-3.3A)
ZN  A   1 ( 3.2A)
None
MLT  A   3 ( 4.2A)
MLT  A   3 ( 4.3A)
 1.05A 4ygfG-3q31A:
6.5		 4ygfG-3q31A:
29.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YGF_H_AZMH303_1
(ALPHA-CARBONIC
ANHYDRASE)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		8 / 9 HIS A 123
HIS A 125
HIS A 142
VAL A 144
VAL A 154
LEU A 214
THR A 215
TRP A 225
 ZN  A   1 ( 3.2A)
ZN  A   1 (-3.3A)
ZN  A   1 ( 3.2A)
None
MLT  A   3 (-4.6A)
MLT  A   3 ( 4.2A)
MLT  A   3 ( 4.3A)
MLT  A   3 (-4.9A)
 0.42A 4ygfH-3q31A:
25.9		 4ygfH-3q31A:
29.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YGF_H_AZMH303_1
(ALPHA-CARBONIC
ANHYDRASE)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		5 / 9 HIS A 125
HIS A 123
VAL A 144
LEU A 214
THR A 215
 ZN  A   1 (-3.3A)
ZN  A   1 ( 3.2A)
None
MLT  A   3 ( 4.2A)
MLT  A   3 ( 4.3A)
 1.39A 4ygfH-3q31A:
25.9		 4ygfH-3q31A:
29.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YGF_H_AZMH303_1
(ALPHA-CARBONIC
ANHYDRASE)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		5 / 9 HIS A 125
HIS A 142
VAL A 144
LEU A 214
THR A 215
 ZN  A   1 (-3.3A)
ZN  A   1 ( 3.2A)
None
MLT  A   3 ( 4.2A)
MLT  A   3 ( 4.3A)
 1.08A 4ygfH-3q31A:
25.9		 4ygfH-3q31A:
29.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YHA_A_MZMA303_1
(ALPHA-CARBONIC
ANHYDRASE)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		8 / 12 HIS A 123
HIS A 125
HIS A 142
VAL A 144
VAL A 154
LEU A 214
THR A 215
TRP A 225
 ZN  A   1 ( 3.2A)
ZN  A   1 (-3.3A)
ZN  A   1 ( 3.2A)
None
MLT  A   3 (-4.6A)
MLT  A   3 ( 4.2A)
MLT  A   3 ( 4.3A)
MLT  A   3 (-4.9A)
 0.55A 4yhaA-3q31A:
26.2		 4yhaA-3q31A:
29.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YHA_B_MZMB303_1
(ALPHA-CARBONIC
ANHYDRASE)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		6 / 10 HIS A 123
HIS A 125
HIS A 142
VAL A 144
LEU A 214
THR A 215
 ZN  A   1 ( 3.2A)
ZN  A   1 (-3.3A)
ZN  A   1 ( 3.2A)
None
MLT  A   3 ( 4.2A)
MLT  A   3 ( 4.3A)
 1.27A 4yhaB-3q31A:
25.3		 4yhaB-3q31A:
29.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YHA_B_MZMB303_1
(ALPHA-CARBONIC
ANHYDRASE)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		7 / 10 HIS A 123
HIS A 125
HIS A 142
VAL A 144
VAL A 154
LEU A 214
THR A 215
 ZN  A   1 ( 3.2A)
ZN  A   1 (-3.3A)
ZN  A   1 ( 3.2A)
None
MLT  A   3 (-4.6A)
MLT  A   3 ( 4.2A)
MLT  A   3 ( 4.3A)
 0.62A 4yhaB-3q31A:
25.3		 4yhaB-3q31A:
29.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YHA_C_MZMC303_1
(ALPHA-CARBONIC
ANHYDRASE)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		8 / 11 HIS A 123
HIS A 125
HIS A 142
VAL A 144
VAL A 154
LEU A 214
THR A 215
TRP A 225
 ZN  A   1 ( 3.2A)
ZN  A   1 (-3.3A)
ZN  A   1 ( 3.2A)
None
MLT  A   3 (-4.6A)
MLT  A   3 ( 4.2A)
MLT  A   3 ( 4.3A)
MLT  A   3 (-4.9A)
 0.47A 4yhaC-3q31A:
26.0		 4yhaC-3q31A:
29.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YHA_D_MZMD302_1
(ALPHA-CARBONIC
ANHYDRASE)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		8 / 11 HIS A 123
HIS A 125
GLU A 129
HIS A 142
VAL A 144
LEU A 214
THR A 215
TRP A 225
 ZN  A   1 ( 3.2A)
ZN  A   1 (-3.3A)
ZN  A   1 ( 4.7A)
ZN  A   1 ( 3.2A)
None
MLT  A   3 ( 4.2A)
MLT  A   3 ( 4.3A)
MLT  A   3 (-4.9A)
 0.43A 4yhaD-3q31A:
25.3		 4yhaD-3q31A:
29.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YHA_D_MZMD302_1
(ALPHA-CARBONIC
ANHYDRASE)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		5 / 11 HIS A 125
GLU A 129
VAL A 154
LEU A 214
THR A 215
 ZN  A   1 (-3.3A)
ZN  A   1 ( 4.7A)
MLT  A   3 (-4.6A)
MLT  A   3 ( 4.2A)
MLT  A   3 ( 4.3A)
 1.03A 4yhaD-3q31A:
25.3		 4yhaD-3q31A:
29.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YHA_E_MZME303_1
(ALPHA-CARBONIC
ANHYDRASE)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		9 / 12 HIS A 123
HIS A 125
HIS A 142
VAL A 144
VAL A 154
LEU A 214
THR A 215
PRO A 218
TRP A 225
 ZN  A   1 ( 3.2A)
ZN  A   1 (-3.3A)
ZN  A   1 ( 3.2A)
None
MLT  A   3 (-4.6A)
MLT  A   3 ( 4.2A)
MLT  A   3 ( 4.3A)
None
MLT  A   3 (-4.9A)
 0.53A 4yhaE-3q31A:
25.9		 4yhaE-3q31A:
29.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YHA_E_MZME303_1
(ALPHA-CARBONIC
ANHYDRASE)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		6 / 12 HIS A 123
HIS A 142
LEU A 214
THR A 215
PRO A 217
TRP A 225
 ZN  A   1 ( 3.2A)
ZN  A   1 ( 3.2A)
MLT  A   3 ( 4.2A)
MLT  A   3 ( 4.3A)
None
MLT  A   3 (-4.9A)
 1.41A 4yhaE-3q31A:
25.9		 4yhaE-3q31A:
29.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YHA_E_MZME303_1
(ALPHA-CARBONIC
ANHYDRASE)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		7 / 12 HIS A 123
HIS A 142
VAL A 154
LEU A 214
THR A 215
PRO A 218
TRP A 225
 ZN  A   1 ( 3.2A)
ZN  A   1 ( 3.2A)
MLT  A   3 (-4.6A)
MLT  A   3 ( 4.2A)
MLT  A   3 ( 4.3A)
None
MLT  A   3 (-4.9A)
 1.43A 4yhaE-3q31A:
25.9		 4yhaE-3q31A:
29.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YHA_E_MZME303_1
(ALPHA-CARBONIC
ANHYDRASE)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		5 / 12 HIS A 125
HIS A 142
VAL A 144
LEU A 214
PRO A 218
 ZN  A   1 (-3.3A)
ZN  A   1 ( 3.2A)
None
MLT  A   3 ( 4.2A)
None
 1.05A 4yhaE-3q31A:
25.9		 4yhaE-3q31A:
29.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YHA_F_MZMF302_1
(ALPHA-CARBONIC
ANHYDRASE)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		7 / 10 HIS A 123
HIS A 125
HIS A 142
VAL A 144
LEU A 214
THR A 215
TRP A 225
 ZN  A   1 ( 3.2A)
ZN  A   1 (-3.3A)
ZN  A   1 ( 3.2A)
None
MLT  A   3 ( 4.2A)
MLT  A   3 ( 4.3A)
MLT  A   3 (-4.9A)
 0.66A 4yhaF-3q31A:
23.6		 4yhaF-3q31A:
29.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YHA_G_MZMG303_1
(ALPHA-CARBONIC
ANHYDRASE)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		8 / 12 HIS A 123
HIS A 125
HIS A 142
VAL A 144
VAL A 154
LEU A 214
THR A 215
TRP A 225
 ZN  A   1 ( 3.2A)
ZN  A   1 (-3.3A)
ZN  A   1 ( 3.2A)
None
MLT  A   3 (-4.6A)
MLT  A   3 ( 4.2A)
MLT  A   3 ( 4.3A)
MLT  A   3 (-4.9A)
 0.43A 4yhaG-3q31A:
26.1		 4yhaG-3q31A:
29.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YHA_G_MZMG303_1
(ALPHA-CARBONIC
ANHYDRASE)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		5 / 12 HIS A 125
HIS A 142
VAL A 144
LEU A 214
THR A 215
 ZN  A   1 (-3.3A)
ZN  A   1 ( 3.2A)
None
MLT  A   3 ( 4.2A)
MLT  A   3 ( 4.3A)
 1.10A 4yhaG-3q31A:
26.1		 4yhaG-3q31A:
29.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YHA_H_MZMH303_1
(ALPHA-CARBONIC
ANHYDRASE)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		8 / 10 HIS A 123
HIS A 125
GLU A 129
HIS A 142
VAL A 144
LEU A 214
THR A 215
TRP A 225
 ZN  A   1 ( 3.2A)
ZN  A   1 (-3.3A)
ZN  A   1 ( 4.7A)
ZN  A   1 ( 3.2A)
None
MLT  A   3 ( 4.2A)
MLT  A   3 ( 4.3A)
MLT  A   3 (-4.9A)
 0.42A 4yhaH-3q31A:
25.8		 4yhaH-3q31A:
29.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A5Z_A_WJZA304_0
(BETA-LACTAMASE NDM-1)		 3g1p PROTEIN PHNP
(Escherichia
coli) 		4 / 8 HIS A  78
ASP A  80
HIS A 143
HIS A 222
 MN  A 400 ( 3.3A)
MLT  A 500 ( 2.8A)
MN  A 400 ( 3.4A)
MN  A 401 (-3.7A)
 0.84A 5a5zA-3g1pA:
9.7		 5a5zA-3g1pA:
21.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ACL_A_SASA1111_1
(MCG)		 5a2r ANGIOTENSIN-CONVERTI
NG ENZYME
(Drosophila
melanogaster) 		4 / 7 TYR A 507
SER A 510
GLU A 395
PHE A 441
 MLT  A1615 (-4.0A)
None
ZN  A1616 (-2.4A)
MLT  A1615 ( 4.8A)
 1.02A 5aclA-5a2rA:
undetectable		 5aclA-5a2rA:
10.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AYA_A_X8ZA307_1
(METALLO-BETA-LACTAMA
SE)		 3g1p PROTEIN PHNP
(Escherichia
coli) 		6 / 11 HIS A  76
HIS A  78
ASP A  80
HIS A  81
HIS A 143
HIS A 222
 MN  A 400 ( 3.4A)
MN  A 400 ( 3.3A)
MLT  A 500 ( 2.8A)
MN  A 401 (-3.5A)
MN  A 400 ( 3.4A)
MN  A 401 (-3.7A)
 0.60A 5ayaA-3g1pA:
10.3		 5ayaA-3g1pA:
22.80
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5C8I_A_MZMA302_1
(CARBONIC ANHYDRASE 2)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		6 / 12 GLN A 102
HIS A 123
HIS A 125
GLU A 129
THR A 215
THR A 216
 None
ZN  A   1 ( 3.2A)
ZN  A   1 (-3.3A)
ZN  A   1 ( 4.7A)
MLT  A   3 ( 4.3A)
MLT  A   3 (-2.8A)
 1.09A 5c8iA-3q31A:
24.4		 5c8iA-3q31A:
30.69
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5C8I_A_MZMA302_1
(CARBONIC ANHYDRASE 2)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		6 / 12 GLN A 102
HIS A 125
GLU A 129
VAL A 144
THR A 215
THR A 216
 None
ZN  A   1 (-3.3A)
ZN  A   1 ( 4.7A)
None
MLT  A   3 ( 4.3A)
MLT  A   3 (-2.8A)
 1.21A 5c8iA-3q31A:
24.4		 5c8iA-3q31A:
30.69
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5C8I_A_MZMA302_1
(CARBONIC ANHYDRASE 2)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		6 / 12 GLN A 121
HIS A 123
GLU A 140
VAL A 144
VAL A 154
TRP A 225
 MLT  A   3 (-3.9A)
ZN  A   1 ( 3.2A)
None
None
MLT  A   3 (-4.6A)
MLT  A   3 (-4.9A)
 1.33A 5c8iA-3q31A:
24.4		 5c8iA-3q31A:
30.69
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5C8I_A_MZMA302_1
(CARBONIC ANHYDRASE 2)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		11 / 12 GLN A 121
HIS A 123
HIS A 125
GLU A 129
VAL A 144
VAL A 154
LEU A 214
THR A 215
THR A 216
PRO A 218
TRP A 225
 MLT  A   3 (-3.9A)
ZN  A   1 ( 3.2A)
ZN  A   1 (-3.3A)
ZN  A   1 ( 4.7A)
None
MLT  A   3 (-4.6A)
MLT  A   3 ( 4.2A)
MLT  A   3 ( 4.3A)
MLT  A   3 (-2.8A)
None
MLT  A   3 (-4.9A)
 0.47A 5c8iA-3q31A:
24.4		 5c8iA-3q31A:
30.69
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5C8I_A_MZMA302_1
(CARBONIC ANHYDRASE 2)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		6 / 12 HIS A 123
VAL A 154
LEU A 214
THR A 216
PRO A 218
TRP A 225
 ZN  A   1 ( 3.2A)
MLT  A   3 (-4.6A)
MLT  A   3 ( 4.2A)
MLT  A   3 (-2.8A)
None
MLT  A   3 (-4.9A)
 1.27A 5c8iA-3q31A:
24.4		 5c8iA-3q31A:
30.69
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5E9Q_A_SAMA301_0
(GENOME POLYPROTEIN)		 5ikm NS5 METHYL
TRANSFERASE
(Dengue
virus) 		10 / 12 GLY A  58
GLY A  81
GLY A  83
GLY A  86
TRP A  87
THR A 104
ASP A 131
VAL A 132
ASP A 146
ILE A 147
 SAM  A 311 (-3.3A)
SAM  A 311 (-3.2A)
SAM  A 311 (-3.3A)
SAM  A 311 (-3.3A)
SAM  A 311 (-3.5A)
SAM  A 311 (-4.5A)
MLT  A 313 ( 2.6A)
SAM  A 311 (-3.7A)
SAM  A 311 (-3.8A)
SAM  A 311 ( 4.3A)
 0.24A 5e9qA-5ikmA:
42.6		 5e9qA-5ikmA:
83.20
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5E9Q_A_SAMA301_0
(GENOME POLYPROTEIN)		 5ikm NS5 METHYL
TRANSFERASE
(Dengue
virus) 		10 / 12 GLY A  58
GLY A  81
GLY A  83
GLY A  86
TRP A  87
THR A 104
LYS A 105
ASP A 131
VAL A 132
ASP A 146
 SAM  A 311 (-3.3A)
SAM  A 311 (-3.2A)
SAM  A 311 (-3.3A)
SAM  A 311 (-3.3A)
SAM  A 311 (-3.5A)
SAM  A 311 (-4.5A)
MLT  A 313 ( 3.0A)
MLT  A 313 ( 2.6A)
SAM  A 311 (-3.7A)
SAM  A 311 (-3.8A)
 0.61A 5e9qA-5ikmA:
42.6		 5e9qA-5ikmA:
83.20
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5E9Q_A_SAMA301_0
(GENOME POLYPROTEIN)		 5ikm NS5 METHYL
TRANSFERASE
(Dengue
virus) 		9 / 12 GLY A  58
GLY A  81
GLY A  83
GLY A  86
TRP A  87
THR A 104
LYS A 105
GLU A 111
ASP A 146
 SAM  A 311 (-3.3A)
SAM  A 311 (-3.2A)
SAM  A 311 (-3.3A)
SAM  A 311 (-3.3A)
SAM  A 311 (-3.5A)
SAM  A 311 (-4.5A)
MLT  A 313 ( 3.0A)
None
SAM  A 311 (-3.8A)
 0.88A 5e9qA-5ikmA:
42.6		 5e9qA-5ikmA:
83.20
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5E9Q_C_SAMC4000_0
(GENOME POLYPROTEIN)		 5ikm NS5 METHYL
TRANSFERASE
(Dengue
virus) 		11 / 12 GLY A  58
GLY A  81
GLY A  83
GLY A  86
TRP A  87
THR A 104
LYS A 105
ASP A 131
VAL A 132
ASP A 146
ILE A 147
 SAM  A 311 (-3.3A)
SAM  A 311 (-3.2A)
SAM  A 311 (-3.3A)
SAM  A 311 (-3.3A)
SAM  A 311 (-3.5A)
SAM  A 311 (-4.5A)
MLT  A 313 ( 3.0A)
MLT  A 313 ( 2.6A)
SAM  A 311 (-3.7A)
SAM  A 311 (-3.8A)
SAM  A 311 ( 4.3A)
 0.53A 5e9qC-5ikmA:
42.8		 5e9qC-5ikmA:
83.20
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5E9Q_C_SAMC4000_0
(GENOME POLYPROTEIN)		 5ikm NS5 METHYL
TRANSFERASE
(Dengue
virus) 		10 / 12 GLY A  58
GLY A  81
GLY A  83
GLY A  86
TRP A  87
THR A 104
LYS A 105
GLU A 111
ASP A 131
ASP A 146
 SAM  A 311 (-3.3A)
SAM  A 311 (-3.2A)
SAM  A 311 (-3.3A)
SAM  A 311 (-3.3A)
SAM  A 311 (-3.5A)
SAM  A 311 (-4.5A)
MLT  A 313 ( 3.0A)
None
MLT  A 313 ( 2.6A)
SAM  A 311 (-3.8A)
 0.72A 5e9qC-5ikmA:
42.8		 5e9qC-5ikmA:
83.20
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5EC8_A_SAMA301_0
(GENOME POLYPROTEIN)		 5ikm NS5 METHYL
TRANSFERASE
(Dengue
virus) 		10 / 12 SER A  56
GLY A  58
GLY A  81
GLY A  83
GLY A  86
TRP A  87
THR A 104
LYS A 105
GLU A 111
ASP A 146
 SAM  A 311 ( 2.7A)
SAM  A 311 (-3.3A)
SAM  A 311 (-3.2A)
SAM  A 311 (-3.3A)
SAM  A 311 (-3.3A)
SAM  A 311 (-3.5A)
SAM  A 311 (-4.5A)
MLT  A 313 ( 3.0A)
None
SAM  A 311 (-3.8A)
 0.96A 5ec8A-5ikmA:
42.7		 5ec8A-5ikmA:
80.73
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5EC8_A_SAMA301_0
(GENOME POLYPROTEIN)		 5ikm NS5 METHYL
TRANSFERASE
(Dengue
virus) 		10 / 12 SER A  56
GLY A  58
GLY A  81
GLY A  83
GLY A  86
TRP A  87
THR A 104
LYS A 105
VAL A 132
ASP A 146
 SAM  A 311 ( 2.7A)
SAM  A 311 (-3.3A)
SAM  A 311 (-3.2A)
SAM  A 311 (-3.3A)
SAM  A 311 (-3.3A)
SAM  A 311 (-3.5A)
SAM  A 311 (-4.5A)
MLT  A 313 ( 3.0A)
SAM  A 311 (-3.7A)
SAM  A 311 (-3.8A)
 0.73A 5ec8A-5ikmA:
42.7		 5ec8A-5ikmA:
80.73
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5EC8_C_SAMC4000_0
(GENOME POLYPROTEIN)		 5ikm NS5 METHYL
TRANSFERASE
(Dengue
virus) 		11 / 12 GLY A  58
GLY A  81
GLY A  83
GLY A  86
TRP A  87
THR A 104
GLU A 111
ASP A 131
VAL A 132
ASP A 146
ILE A 147
 SAM  A 311 (-3.3A)
SAM  A 311 (-3.2A)
SAM  A 311 (-3.3A)
SAM  A 311 (-3.3A)
SAM  A 311 (-3.5A)
SAM  A 311 (-4.5A)
None
MLT  A 313 ( 2.6A)
SAM  A 311 (-3.7A)
SAM  A 311 (-3.8A)
SAM  A 311 ( 4.3A)
 0.49A 5ec8C-5ikmA:
42.5		 5ec8C-5ikmA:
80.73
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5EHG_A_SAMA301_0
(RNA-DIRECTED RNA
POLYMERASE NS5)		 5ikm NS5 METHYL
TRANSFERASE
(Dengue
virus) 		11 / 12 GLY A  58
GLY A  81
GLY A  83
GLY A  86
TRP A  87
THR A 104
LYS A 105
ASP A 131
VAL A 132
ASP A 146
ILE A 147
 SAM  A 311 (-3.3A)
SAM  A 311 (-3.2A)
SAM  A 311 (-3.3A)
SAM  A 311 (-3.3A)
SAM  A 311 (-3.5A)
SAM  A 311 (-4.5A)
MLT  A 313 ( 3.0A)
MLT  A 313 ( 2.6A)
SAM  A 311 (-3.7A)
SAM  A 311 (-3.8A)
SAM  A 311 ( 4.3A)
 0.49A 5ehgA-5ikmA:
42.6		 5ehgA-5ikmA:
80.73
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5EHG_A_SAMA301_0
(RNA-DIRECTED RNA
POLYMERASE NS5)		 5ikm NS5 METHYL
TRANSFERASE
(Dengue
virus) 		7 / 12 GLY A  58
GLY A  86
TRP A  87
THR A 104
LYS A 105
GLU A 111
ASP A 146
 SAM  A 311 (-3.3A)
SAM  A 311 (-3.3A)
SAM  A 311 (-3.5A)
SAM  A 311 (-4.5A)
MLT  A 313 ( 3.0A)
None
SAM  A 311 (-3.8A)
 1.04A 5ehgA-5ikmA:
42.6		 5ehgA-5ikmA:
80.73
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5EHI_A_SAMA4001_0
(NS5
METHYLTRANSFERASE
DENGUE VIRUS)		 5ikm NS5 METHYL
TRANSFERASE
(Dengue
virus) 		11 / 12 GLY A  58
GLY A  81
GLY A  83
GLY A  86
TRP A  87
THR A 104
LYS A 105
ASP A 131
VAL A 132
ASP A 146
ILE A 147
 SAM  A 311 (-3.3A)
SAM  A 311 (-3.2A)
SAM  A 311 (-3.3A)
SAM  A 311 (-3.3A)
SAM  A 311 (-3.5A)
SAM  A 311 (-4.5A)
MLT  A 313 ( 3.0A)
MLT  A 313 ( 2.6A)
SAM  A 311 (-3.7A)
SAM  A 311 (-3.8A)
SAM  A 311 ( 4.3A)
 0.54A 5ehiA-5ikmA:
42.8		 5ehiA-5ikmA:
80.73
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5EHI_A_SAMA4001_0
(NS5
METHYLTRANSFERASE
DENGUE VIRUS)		 5ikm NS5 METHYL
TRANSFERASE
(Dengue
virus) 		7 / 12 GLY A  83
GLY A  86
THR A 104
LYS A 105
GLU A 111
ASP A 131
VAL A 132
 SAM  A 311 (-3.3A)
SAM  A 311 (-3.3A)
SAM  A 311 (-4.5A)
MLT  A 313 ( 3.0A)
None
MLT  A 313 ( 2.6A)
SAM  A 311 (-3.7A)
 0.74A 5ehiA-5ikmA:
42.8		 5ehiA-5ikmA:
80.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EHI_C_SAMC4000_0
(NS5
METHYLTRANSFERASE
DENGUE VIRUS)		 5ikm NS5 METHYL
TRANSFERASE
(Dengue
virus) 		11 / 12 GLY A  58
GLY A  81
GLY A  83
GLY A  86
TRP A  87
THR A 104
LYS A 105
ASP A 131
VAL A 132
ASP A 146
ILE A 147
 SAM  A 311 (-3.3A)
SAM  A 311 (-3.2A)
SAM  A 311 (-3.3A)
SAM  A 311 (-3.3A)
SAM  A 311 (-3.5A)
SAM  A 311 (-4.5A)
MLT  A 313 ( 3.0A)
MLT  A 313 ( 2.6A)
SAM  A 311 (-3.7A)
SAM  A 311 (-3.8A)
SAM  A 311 ( 4.3A)
 0.33A 5ehiC-5ikmA:
42.9		 5ehiC-5ikmA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EHI_C_SAMC4000_0
(NS5
METHYLTRANSFERASE
DENGUE VIRUS)		 5ikm NS5 METHYL
TRANSFERASE
(Dengue
virus) 		9 / 12 GLY A  81
GLY A  83
GLY A  86
THR A 104
LYS A 105
GLU A 111
ASP A 131
VAL A 132
ILE A 147
 SAM  A 311 (-3.2A)
SAM  A 311 (-3.3A)
SAM  A 311 (-3.3A)
SAM  A 311 (-4.5A)
MLT  A 313 ( 3.0A)
None
MLT  A 313 ( 2.6A)
SAM  A 311 (-3.7A)
SAM  A 311 ( 4.3A)
 0.58A 5ehiC-5ikmA:
42.9		 5ehiC-5ikmA:
undetectable
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5EIF_A_SAMA301_0
(GENOME POLYPROTEIN)		 5ikm NS5 METHYL
TRANSFERASE
(Dengue
virus) 		11 / 12 GLY A  58
GLY A  81
GLY A  83
GLY A  86
TRP A  87
THR A 104
LYS A 105
ASP A 131
VAL A 132
ASP A 146
ILE A 147
 SAM  A 311 (-3.3A)
SAM  A 311 (-3.2A)
SAM  A 311 (-3.3A)
SAM  A 311 (-3.3A)
SAM  A 311 (-3.5A)
SAM  A 311 (-4.5A)
MLT  A 313 ( 3.0A)
MLT  A 313 ( 2.6A)
SAM  A 311 (-3.7A)
SAM  A 311 (-3.8A)
SAM  A 311 ( 4.3A)
 0.52A 5eifA-5ikmA:
42.8		 5eifA-5ikmA:
80.73
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5EIF_C_SAMC4000_0
(GENOME POLYPROTEIN)		 5ikm NS5 METHYL
TRANSFERASE
(Dengue
virus) 		11 / 12 GLY A  58
GLY A  81
GLY A  83
GLY A  86
TRP A  87
THR A 104
LYS A 105
ASP A 131
VAL A 132
ASP A 146
ILE A 147
 SAM  A 311 (-3.3A)
SAM  A 311 (-3.2A)
SAM  A 311 (-3.3A)
SAM  A 311 (-3.3A)
SAM  A 311 (-3.5A)
SAM  A 311 (-4.5A)
MLT  A 313 ( 3.0A)
MLT  A 313 ( 2.6A)
SAM  A 311 (-3.7A)
SAM  A 311 (-3.8A)
SAM  A 311 ( 4.3A)
 0.39A 5eifC-5ikmA:
42.8		 5eifC-5ikmA:
80.73
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5EIW_A_SAMA301_0
(NS5
METHYLTRANSFERASE)		 5ikm NS5 METHYL
TRANSFERASE
(Dengue
virus) 		10 / 12 GLY A  58
GLY A  81
GLY A  83
GLY A  86
TRP A  87
THR A 104
ASP A 131
VAL A 132
ASP A 146
ILE A 147
 SAM  A 311 (-3.3A)
SAM  A 311 (-3.2A)
SAM  A 311 (-3.3A)
SAM  A 311 (-3.3A)
SAM  A 311 (-3.5A)
SAM  A 311 (-4.5A)
MLT  A 313 ( 2.6A)
SAM  A 311 (-3.7A)
SAM  A 311 (-3.8A)
SAM  A 311 ( 4.3A)
 0.24A 5eiwA-5ikmA:
42.7		 5eiwA-5ikmA:
80.73
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5EIW_A_SAMA301_0
(NS5
METHYLTRANSFERASE)		 5ikm NS5 METHYL
TRANSFERASE
(Dengue
virus) 		10 / 12 GLY A  58
GLY A  81
GLY A  83
GLY A  86
TRP A  87
THR A 104
LYS A 105
ASP A 131
VAL A 132
ASP A 146
 SAM  A 311 (-3.3A)
SAM  A 311 (-3.2A)
SAM  A 311 (-3.3A)
SAM  A 311 (-3.3A)
SAM  A 311 (-3.5A)
SAM  A 311 (-4.5A)
MLT  A 313 ( 3.0A)
MLT  A 313 ( 2.6A)
SAM  A 311 (-3.7A)
SAM  A 311 (-3.8A)
 0.50A 5eiwA-5ikmA:
42.7		 5eiwA-5ikmA:
80.73
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5EIW_A_SAMA301_0
(NS5
METHYLTRANSFERASE)		 5ikm NS5 METHYL
TRANSFERASE
(Dengue
virus) 		8 / 12 GLY A  81
GLY A  83
GLY A  86
THR A 104
GLU A 111
ASP A 131
VAL A 132
ILE A 147
 SAM  A 311 (-3.2A)
SAM  A 311 (-3.3A)
SAM  A 311 (-3.3A)
SAM  A 311 (-4.5A)
None
MLT  A 313 ( 2.6A)
SAM  A 311 (-3.7A)
SAM  A 311 ( 4.3A)
 0.49A 5eiwA-5ikmA:
42.7		 5eiwA-5ikmA:
80.73
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5EIW_A_SAMA301_0
(NS5
METHYLTRANSFERASE)		 5ikm NS5 METHYL
TRANSFERASE
(Dengue
virus) 		8 / 12 GLY A  81
GLY A  83
GLY A  86
THR A 104
LYS A 105
GLU A 111
ASP A 131
VAL A 132
 SAM  A 311 (-3.2A)
SAM  A 311 (-3.3A)
SAM  A 311 (-3.3A)
SAM  A 311 (-4.5A)
MLT  A 313 ( 3.0A)
None
MLT  A 313 ( 2.6A)
SAM  A 311 (-3.7A)
 0.61A 5eiwA-5ikmA:
42.7		 5eiwA-5ikmA:
80.73
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5EIW_C_SAMC4000_0
(NS5
METHYLTRANSFERASE)		 5ikm NS5 METHYL
TRANSFERASE
(Dengue
virus) 		11 / 12 GLY A  58
GLY A  81
GLY A  83
GLY A  86
TRP A  87
THR A 104
LYS A 105
ASP A 131
VAL A 132
ASP A 146
ILE A 147
 SAM  A 311 (-3.3A)
SAM  A 311 (-3.2A)
SAM  A 311 (-3.3A)
SAM  A 311 (-3.3A)
SAM  A 311 (-3.5A)
SAM  A 311 (-4.5A)
MLT  A 313 ( 3.0A)
MLT  A 313 ( 2.6A)
SAM  A 311 (-3.7A)
SAM  A 311 (-3.8A)
SAM  A 311 ( 4.3A)
 0.35A 5eiwC-5ikmA:
42.6		 5eiwC-5ikmA:
80.73
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5EIW_C_SAMC4000_0
(NS5
METHYLTRANSFERASE)		 5ikm NS5 METHYL
TRANSFERASE
(Dengue
virus) 		9 / 12 GLY A  58
GLY A  81
GLY A  83
GLY A  86
TRP A  87
THR A 104
LYS A 105
GLU A 111
ASP A 146
 SAM  A 311 (-3.3A)
SAM  A 311 (-3.2A)
SAM  A 311 (-3.3A)
SAM  A 311 (-3.3A)
SAM  A 311 (-3.5A)
SAM  A 311 (-4.5A)
MLT  A 313 ( 3.0A)
None
SAM  A 311 (-3.8A)
 0.68A 5eiwC-5ikmA:
42.6		 5eiwC-5ikmA:
80.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EKX_A_SAMA301_0
(NS5
METHYLTRANSFERASE)		 5ikm NS5 METHYL
TRANSFERASE
(Dengue
virus) 		11 / 12 SER A  56
GLY A  58
GLY A  81
GLY A  83
GLY A  86
TRP A  87
THR A 104
ASP A 131
VAL A 132
ASP A 146
ILE A 147
 SAM  A 311 ( 2.7A)
SAM  A 311 (-3.3A)
SAM  A 311 (-3.2A)
SAM  A 311 (-3.3A)
SAM  A 311 (-3.3A)
SAM  A 311 (-3.5A)
SAM  A 311 (-4.5A)
MLT  A 313 ( 2.6A)
SAM  A 311 (-3.7A)
SAM  A 311 (-3.8A)
SAM  A 311 ( 4.3A)
 0.22A 5ekxA-5ikmA:
42.9		 5ekxA-5ikmA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EKX_A_SAMA301_0
(NS5
METHYLTRANSFERASE)		 5ikm NS5 METHYL
TRANSFERASE
(Dengue
virus) 		11 / 12 SER A  56
GLY A  58
GLY A  81
GLY A  83
GLY A  86
TRP A  87
THR A 104
LYS A 105
ASP A 131
VAL A 132
ASP A 146
 SAM  A 311 ( 2.7A)
SAM  A 311 (-3.3A)
SAM  A 311 (-3.2A)
SAM  A 311 (-3.3A)
SAM  A 311 (-3.3A)
SAM  A 311 (-3.5A)
SAM  A 311 (-4.5A)
MLT  A 313 ( 3.0A)
MLT  A 313 ( 2.6A)
SAM  A 311 (-3.7A)
SAM  A 311 (-3.8A)
 0.55A 5ekxA-5ikmA:
42.9		 5ekxA-5ikmA:
undetectable
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5EKX_B_SAMB4000_0
(NS5
METHYLTRANSFERASE)		 5ikm NS5 METHYL
TRANSFERASE
(Dengue
virus) 		11 / 12 GLY A  58
GLY A  81
GLY A  83
GLY A  86
TRP A  87
THR A 104
LYS A 105
HIS A 110
VAL A 132
ASP A 146
ILE A 147
 SAM  A 311 (-3.3A)
SAM  A 311 (-3.2A)
SAM  A 311 (-3.3A)
SAM  A 311 (-3.3A)
SAM  A 311 (-3.5A)
SAM  A 311 (-4.5A)
MLT  A 313 ( 3.0A)
SAM  A 311 (-4.1A)
SAM  A 311 (-3.7A)
SAM  A 311 (-3.8A)
SAM  A 311 ( 4.3A)
 0.66A 5ekxB-5ikmA:
42.9		 5ekxB-5ikmA:
80.73
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5EKX_B_SAMB4000_0
(NS5
METHYLTRANSFERASE)		 5ikm NS5 METHYL
TRANSFERASE
(Dengue
virus) 		9 / 12 GLY A  81
GLY A  83
GLY A  86
THR A 104
LYS A 105
HIS A 110
GLU A 111
VAL A 132
ILE A 147
 SAM  A 311 (-3.2A)
SAM  A 311 (-3.3A)
SAM  A 311 (-3.3A)
SAM  A 311 (-4.5A)
MLT  A 313 ( 3.0A)
SAM  A 311 (-4.1A)
None
SAM  A 311 (-3.7A)
SAM  A 311 ( 4.3A)
 0.89A 5ekxB-5ikmA:
42.9		 5ekxB-5ikmA:
80.73
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5HG0_A_SAMA301_0
(PANTOTHENATE
SYNTHETASE)		 3uk2 PANTOTHENATE
SYNTHETASE
(Burkholderia
thailandensis) 		11 / 12 HIS A  30
GLY A  32
LEU A  36
GLN A  57
TYR A  67
VAL A 128
GLY A 144
LYS A 146
ASP A 147
THR A 172
LEU A 181
 AMP  A 280 (-4.7A)
AMP  A 280 ( 3.9A)
AMP  A 280 (-4.7A)
EDO  A 285 ( 3.0A)
None
EDO  A 285 (-4.9A)
AMP  A 280 (-3.3A)
None
MLT  A 284 ( 3.5A)
AMP  A 280 (-4.2A)
AMP  A 280 (-4.4A)
 0.44A 5hg0A-3uk2A:
33.1		 5hg0A-3uk2A:
35.52
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5HG0_A_SAMA301_0
(PANTOTHENATE
SYNTHETASE)		 3uk2 PANTOTHENATE
SYNTHETASE
(Burkholderia
thailandensis) 		5 / 12 HIS A  30
GLY A  32
VAL A 129
ASP A 147
LEU A 181
 AMP  A 280 (-4.7A)
AMP  A 280 ( 3.9A)
None
MLT  A 284 ( 3.5A)
AMP  A 280 (-4.4A)
 1.10A 5hg0A-3uk2A:
33.1		 5hg0A-3uk2A:
35.52
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5HG0_A_SAMA301_0
(PANTOTHENATE
SYNTHETASE)		 3uk2 PANTOTHENATE
SYNTHETASE
(Burkholderia
thailandensis) 		6 / 12 HIS A  33
GLY A  32
GLN A  57
TYR A  67
GLY A 144
ASP A 147
 AMP  A 280 (-4.0A)
AMP  A 280 ( 3.9A)
EDO  A 285 ( 3.0A)
None
AMP  A 280 (-3.3A)
MLT  A 284 ( 3.5A)
 1.40A 5hg0A-3uk2A:
33.1		 5hg0A-3uk2A:
35.52
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5HG0_B_SAMB301_0
(PANTOTHENATE
SYNTHETASE)		 3uk2 PANTOTHENATE
SYNTHETASE
(Burkholderia
thailandensis) 		10 / 12 HIS A  30
GLY A  32
HIS A  33
LEU A  36
TYR A  67
VAL A 128
GLY A 144
ASP A 147
THR A 172
LEU A 181
 AMP  A 280 (-4.7A)
AMP  A 280 ( 3.9A)
AMP  A 280 (-4.0A)
AMP  A 280 (-4.7A)
None
EDO  A 285 (-4.9A)
AMP  A 280 (-3.3A)
MLT  A 284 ( 3.5A)
AMP  A 280 (-4.2A)
AMP  A 280 (-4.4A)
 0.28A 5hg0B-3uk2A:
33.0		 5hg0B-3uk2A:
35.52
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5HG0_B_SAMB301_0
(PANTOTHENATE
SYNTHETASE)		 3uk2 PANTOTHENATE
SYNTHETASE
(Burkholderia
thailandensis) 		6 / 12 HIS A  30
GLY A  32
HIS A  33
VAL A 129
ASP A 147
LEU A 181
 AMP  A 280 (-4.7A)
AMP  A 280 ( 3.9A)
AMP  A 280 (-4.0A)
None
MLT  A 284 ( 3.5A)
AMP  A 280 (-4.4A)
 1.09A 5hg0B-3uk2A:
33.0		 5hg0B-3uk2A:
35.52
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5HG0_B_SAMB301_0
(PANTOTHENATE
SYNTHETASE)		 3uk2 PANTOTHENATE
SYNTHETASE
(Burkholderia
thailandensis) 		10 / 12 HIS A  30
GLY A  32
LEU A  36
TYR A  67
VAL A 128
GLY A 144
LYS A 146
ASP A 147
THR A 172
LEU A 181
 AMP  A 280 (-4.7A)
AMP  A 280 ( 3.9A)
AMP  A 280 (-4.7A)
None
EDO  A 285 (-4.9A)
AMP  A 280 (-3.3A)
None
MLT  A 284 ( 3.5A)
AMP  A 280 (-4.2A)
AMP  A 280 (-4.4A)
 0.52A 5hg0B-3uk2A:
33.0		 5hg0B-3uk2A:
35.52
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5HG0_B_SAMB301_0
(PANTOTHENATE
SYNTHETASE)		 3uk2 PANTOTHENATE
SYNTHETASE
(Burkholderia
thailandensis) 		6 / 12 HIS A  30
GLY A  32
VAL A 129
LYS A 146
ASP A 147
LEU A 181
 AMP  A 280 (-4.7A)
AMP  A 280 ( 3.9A)
None
None
MLT  A 284 ( 3.5A)
AMP  A 280 (-4.4A)
 1.22A 5hg0B-3uk2A:
33.0		 5hg0B-3uk2A:
35.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HWK_A_BEZA301_0
(GLUTATHIONE-SPECIFIC
GAMMA-GLUTAMYLCYCLOT
RANSFERASE)		 5kvu ISOCITRATE
DEHYDROGENASE
(Mycobacterium
tuberculosis) 		5 / 10 GLY A 413
GLY A 546
LEU A 414
GLU A 421
TYR A 422
 None
None
None
None
MLT  A 802 (-4.0A)
 1.33A 5hwkA-5kvuA:
undetectable		 5hwkA-5kvuA:
15.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HWK_B_BEZB301_0
(GLUTATHIONE-SPECIFIC
GAMMA-GLUTAMYLCYCLOT
RANSFERASE)		 5kvu ISOCITRATE
DEHYDROGENASE
(Mycobacterium
tuberculosis) 		5 / 10 GLY A 413
GLY A 546
LEU A 414
GLU A 421
TYR A 422
 None
None
None
None
MLT  A 802 (-4.0A)
 1.32A 5hwkB-5kvuA:
undetectable		 5hwkB-5kvuA:
15.84
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5IKM_A_SAMA311_0
(NS5 METHYL
TRANSFERASE)		 5ikm NS5 METHYL
TRANSFERASE
(Dengue
virus) 		12 / 12 GLY A  58
GLY A  81
GLY A  83
GLY A  86
TRP A  87
THR A 104
LYS A 105
HIS A 110
ASP A 131
VAL A 132
ASP A 146
ILE A 147
 SAM  A 311 (-3.3A)
SAM  A 311 (-3.2A)
SAM  A 311 (-3.3A)
SAM  A 311 (-3.3A)
SAM  A 311 (-3.5A)
SAM  A 311 (-4.5A)
MLT  A 313 ( 3.0A)
SAM  A 311 (-4.1A)
MLT  A 313 ( 2.6A)
SAM  A 311 (-3.7A)
SAM  A 311 (-3.8A)
SAM  A 311 ( 4.3A)
 0.43A 5ikmA-5ikmA:
47.4		 5ikmA-5ikmA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JN8_A_AZMA701_1
(CARBONIC ANHYDRASE 4)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		6 / 10 GLN A 102
HIS A 123
HIS A 125
HIS A 142
THR A 215
THR A 216
 None
ZN  A   1 ( 3.2A)
ZN  A   1 (-3.3A)
ZN  A   1 ( 3.2A)
MLT  A   3 ( 4.3A)
MLT  A   3 (-2.8A)
 1.05A 5jn8A-3q31A:
24.2		 5jn8A-3q31A:
30.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JN8_A_AZMA701_1
(CARBONIC ANHYDRASE 4)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		6 / 10 GLN A 102
HIS A 123
HIS A 125
VAL A 144
THR A 215
THR A 216
 None
ZN  A   1 ( 3.2A)
ZN  A   1 (-3.3A)
None
MLT  A   3 ( 4.3A)
MLT  A   3 (-2.8A)
 1.21A 5jn8A-3q31A:
24.2		 5jn8A-3q31A:
30.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JN8_A_AZMA701_1
(CARBONIC ANHYDRASE 4)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		10 / 10 GLN A 121
HIS A 123
HIS A 125
HIS A 142
VAL A 144
VAL A 154
LEU A 214
THR A 215
THR A 216
TRP A 225
 MLT  A   3 (-3.9A)
ZN  A   1 ( 3.2A)
ZN  A   1 (-3.3A)
ZN  A   1 ( 3.2A)
None
MLT  A   3 (-4.6A)
MLT  A   3 ( 4.2A)
MLT  A   3 ( 4.3A)
MLT  A   3 (-2.8A)
MLT  A   3 (-4.9A)
 0.41A 5jn8A-3q31A:
24.2		 5jn8A-3q31A:
30.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JN8_A_AZMA701_1
(CARBONIC ANHYDRASE 4)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		6 / 10 HIS A 123
HIS A 125
VAL A 144
LEU A 214
THR A 215
THR A 216
 ZN  A   1 ( 3.2A)
ZN  A   1 (-3.3A)
None
MLT  A   3 ( 4.2A)
MLT  A   3 ( 4.3A)
MLT  A   3 (-2.8A)
 1.19A 5jn8A-3q31A:
24.2		 5jn8A-3q31A:
30.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JN8_A_AZMA701_1
(CARBONIC ANHYDRASE 4)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		7 / 10 HIS A 123
HIS A 142
VAL A 154
LEU A 214
THR A 215
THR A 216
TRP A 225
 ZN  A   1 ( 3.2A)
ZN  A   1 ( 3.2A)
MLT  A   3 (-4.6A)
MLT  A   3 ( 4.2A)
MLT  A   3 ( 4.3A)
MLT  A   3 (-2.8A)
MLT  A   3 (-4.9A)
 1.41A 5jn8A-3q31A:
24.2		 5jn8A-3q31A:
30.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JN8_A_AZMA701_1
(CARBONIC ANHYDRASE 4)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		5 / 10 HIS A 125
HIS A 123
VAL A 144
LEU A 214
THR A 215
 ZN  A   1 (-3.3A)
ZN  A   1 ( 3.2A)
None
MLT  A   3 ( 4.2A)
MLT  A   3 ( 4.3A)
 1.40A 5jn8A-3q31A:
24.2		 5jn8A-3q31A:
30.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JN8_A_AZMA701_1
(CARBONIC ANHYDRASE 4)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		5 / 10 HIS A 142
HIS A 125
VAL A 154
LEU A 214
THR A 216
 ZN  A   1 ( 3.2A)
ZN  A   1 (-3.3A)
MLT  A   3 (-4.6A)
MLT  A   3 ( 4.2A)
MLT  A   3 (-2.8A)
 1.39A 5jn8A-3q31A:
24.2		 5jn8A-3q31A:
30.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JN8_B_AZMB701_1
(CARBONIC ANHYDRASE 4)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		7 / 11 GLN A 102
HIS A 123
HIS A 125
GLU A 129
HIS A 142
THR A 215
THR A 216
 None
ZN  A   1 ( 3.2A)
ZN  A   1 (-3.3A)
ZN  A   1 ( 4.7A)
ZN  A   1 ( 3.2A)
MLT  A   3 ( 4.3A)
MLT  A   3 (-2.8A)
 1.05A 5jn8B-3q31A:
24.3		 5jn8B-3q31A:
30.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JN8_B_AZMB701_1
(CARBONIC ANHYDRASE 4)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		6 / 11 GLN A 102
HIS A 123
HIS A 125
VAL A 144
THR A 215
THR A 216
 None
ZN  A   1 ( 3.2A)
ZN  A   1 (-3.3A)
None
MLT  A   3 ( 4.3A)
MLT  A   3 (-2.8A)
 1.22A 5jn8B-3q31A:
24.3		 5jn8B-3q31A:
30.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JN8_B_AZMB701_1
(CARBONIC ANHYDRASE 4)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		6 / 11 GLN A 121
GLU A 140
HIS A 142
VAL A 144
VAL A 154
TRP A 225
 MLT  A   3 (-3.9A)
None
ZN  A   1 ( 3.2A)
None
MLT  A   3 (-4.6A)
MLT  A   3 (-4.9A)
 1.47A 5jn8B-3q31A:
24.3		 5jn8B-3q31A:
30.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JN8_B_AZMB701_1
(CARBONIC ANHYDRASE 4)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		11 / 11 GLN A 121
HIS A 123
HIS A 125
GLU A 129
HIS A 142
VAL A 144
VAL A 154
LEU A 214
THR A 215
THR A 216
TRP A 225
 MLT  A   3 (-3.9A)
ZN  A   1 ( 3.2A)
ZN  A   1 (-3.3A)
ZN  A   1 ( 4.7A)
ZN  A   1 ( 3.2A)
None
MLT  A   3 (-4.6A)
MLT  A   3 ( 4.2A)
MLT  A   3 ( 4.3A)
MLT  A   3 (-2.8A)
MLT  A   3 (-4.9A)
 0.39A 5jn8B-3q31A:
24.3		 5jn8B-3q31A:
30.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JN8_B_AZMB701_1
(CARBONIC ANHYDRASE 4)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		6 / 11 HIS A 123
HIS A 125
VAL A 144
LEU A 214
THR A 215
THR A 216
 ZN  A   1 ( 3.2A)
ZN  A   1 (-3.3A)
None
MLT  A   3 ( 4.2A)
MLT  A   3 ( 4.3A)
MLT  A   3 (-2.8A)
 1.18A 5jn8B-3q31A:
24.3		 5jn8B-3q31A:
30.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JN8_B_AZMB701_1
(CARBONIC ANHYDRASE 4)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		7 / 11 HIS A 123
HIS A 142
VAL A 154
LEU A 214
THR A 215
THR A 216
TRP A 225
 ZN  A   1 ( 3.2A)
ZN  A   1 ( 3.2A)
MLT  A   3 (-4.6A)
MLT  A   3 ( 4.2A)
MLT  A   3 ( 4.3A)
MLT  A   3 (-2.8A)
MLT  A   3 (-4.9A)
 1.44A 5jn8B-3q31A:
24.3		 5jn8B-3q31A:
30.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JN8_B_AZMB701_1
(CARBONIC ANHYDRASE 4)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		6 / 11 HIS A 125
GLU A 129
VAL A 154
LEU A 214
THR A 215
THR A 216
 ZN  A   1 (-3.3A)
ZN  A   1 ( 4.7A)
MLT  A   3 (-4.6A)
MLT  A   3 ( 4.2A)
MLT  A   3 ( 4.3A)
MLT  A   3 (-2.8A)
 0.99A 5jn8B-3q31A:
24.3		 5jn8B-3q31A:
30.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JN8_C_AZMC701_1
(CARBONIC ANHYDRASE 4)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		5 / 9 GLN A 102
HIS A 123
HIS A 125
THR A 215
THR A 216
 None
ZN  A   1 ( 3.2A)
ZN  A   1 (-3.3A)
MLT  A   3 ( 4.3A)
MLT  A   3 (-2.8A)
 1.13A 5jn8C-3q31A:
24.1		 5jn8C-3q31A:
30.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JN8_C_AZMC701_1
(CARBONIC ANHYDRASE 4)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		9 / 9 GLN A 121
HIS A 123
HIS A 125
HIS A 142
VAL A 144
LEU A 214
THR A 215
THR A 216
TRP A 225
 MLT  A   3 (-3.9A)
ZN  A   1 ( 3.2A)
ZN  A   1 (-3.3A)
ZN  A   1 ( 3.2A)
None
MLT  A   3 ( 4.2A)
MLT  A   3 ( 4.3A)
MLT  A   3 (-2.8A)
MLT  A   3 (-4.9A)
 0.37A 5jn8C-3q31A:
24.1		 5jn8C-3q31A:
30.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JN8_C_AZMC701_1
(CARBONIC ANHYDRASE 4)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		6 / 9 HIS A 123
HIS A 142
LEU A 214
THR A 215
THR A 216
TRP A 225
 ZN  A   1 ( 3.2A)
ZN  A   1 ( 3.2A)
MLT  A   3 ( 4.2A)
MLT  A   3 ( 4.3A)
MLT  A   3 (-2.8A)
MLT  A   3 (-4.9A)
 1.46A 5jn8C-3q31A:
24.1		 5jn8C-3q31A:
30.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JN8_C_AZMC701_1
(CARBONIC ANHYDRASE 4)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		5 / 9 HIS A 125
VAL A 154
LEU A 214
THR A 215
THR A 216
 ZN  A   1 (-3.3A)
MLT  A   3 (-4.6A)
MLT  A   3 ( 4.2A)
MLT  A   3 ( 4.3A)
MLT  A   3 (-2.8A)
 1.05A 5jn8C-3q31A:
24.1		 5jn8C-3q31A:
30.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JN8_C_AZMC701_1
(CARBONIC ANHYDRASE 4)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		5 / 9 HIS A 142
HIS A 125
VAL A 154
LEU A 214
THR A 216
 ZN  A   1 ( 3.2A)
ZN  A   1 (-3.3A)
MLT  A   3 (-4.6A)
MLT  A   3 ( 4.2A)
MLT  A   3 (-2.8A)
 1.41A 5jn8C-3q31A:
24.1		 5jn8C-3q31A:
30.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JN8_D_AZMD701_1
(CARBONIC ANHYDRASE 4)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		6 / 10 GLN A 102
HIS A 123
HIS A 125
GLU A 129
THR A 215
THR A 216
 None
ZN  A   1 ( 3.2A)
ZN  A   1 (-3.3A)
ZN  A   1 ( 4.7A)
MLT  A   3 ( 4.3A)
MLT  A   3 (-2.8A)
 1.10A 5jn8D-3q31A:
24.0		 5jn8D-3q31A:
30.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JN8_D_AZMD701_1
(CARBONIC ANHYDRASE 4)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		5 / 10 GLN A 121
HIS A 123
GLU A 140
VAL A 144
THR A 215
 MLT  A   3 (-3.9A)
ZN  A   1 ( 3.2A)
None
None
MLT  A   3 ( 4.3A)
 1.26A 5jn8D-3q31A:
24.0		 5jn8D-3q31A:
30.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JN8_D_AZMD701_1
(CARBONIC ANHYDRASE 4)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		10 / 10 GLN A 121
HIS A 123
HIS A 125
GLU A 129
HIS A 142
VAL A 144
LEU A 214
THR A 215
THR A 216
TRP A 225
 MLT  A   3 (-3.9A)
ZN  A   1 ( 3.2A)
ZN  A   1 (-3.3A)
ZN  A   1 ( 4.7A)
ZN  A   1 ( 3.2A)
None
MLT  A   3 ( 4.2A)
MLT  A   3 ( 4.3A)
MLT  A   3 (-2.8A)
MLT  A   3 (-4.9A)
 0.33A 5jn8D-3q31A:
24.0		 5jn8D-3q31A:
30.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JN8_D_AZMD701_1
(CARBONIC ANHYDRASE 4)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		6 / 10 HIS A 123
HIS A 142
LEU A 214
THR A 215
THR A 216
TRP A 225
 ZN  A   1 ( 3.2A)
ZN  A   1 ( 3.2A)
MLT  A   3 ( 4.2A)
MLT  A   3 ( 4.3A)
MLT  A   3 (-2.8A)
MLT  A   3 (-4.9A)
 1.46A 5jn8D-3q31A:
24.0		 5jn8D-3q31A:
30.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JN8_D_AZMD701_1
(CARBONIC ANHYDRASE 4)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		6 / 10 HIS A 125
GLU A 129
VAL A 154
LEU A 214
THR A 215
THR A 216
 ZN  A   1 (-3.3A)
ZN  A   1 ( 4.7A)
MLT  A   3 (-4.6A)
MLT  A   3 ( 4.2A)
MLT  A   3 ( 4.3A)
MLT  A   3 (-2.8A)
 0.97A 5jn8D-3q31A:
24.0		 5jn8D-3q31A:
30.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JN8_D_AZMD701_1
(CARBONIC ANHYDRASE 4)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		5 / 10 HIS A 142
HIS A 125
VAL A 154
LEU A 214
THR A 216
 ZN  A   1 ( 3.2A)
ZN  A   1 (-3.3A)
MLT  A   3 (-4.6A)
MLT  A   3 ( 4.2A)
MLT  A   3 (-2.8A)
 1.37A 5jn8D-3q31A:
24.0		 5jn8D-3q31A:
30.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JN9_A_EZLA302_1
(CARBONIC ANHYDRASE 4)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		6 / 10 GLN A 102
HIS A 123
HIS A 125
HIS A 142
THR A 215
THR A 216
 None
ZN  A   1 ( 3.2A)
ZN  A   1 (-3.3A)
ZN  A   1 ( 3.2A)
MLT  A   3 ( 4.3A)
MLT  A   3 (-2.8A)
 1.11A 5jn9A-3q31A:
24.3		 5jn9A-3q31A:
30.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JN9_A_EZLA302_1
(CARBONIC ANHYDRASE 4)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		6 / 10 GLN A 102
HIS A 123
HIS A 125
VAL A 144
THR A 215
THR A 216
 None
ZN  A   1 ( 3.2A)
ZN  A   1 (-3.3A)
None
MLT  A   3 ( 4.3A)
MLT  A   3 (-2.8A)
 1.26A 5jn9A-3q31A:
24.3		 5jn9A-3q31A:
30.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JN9_A_EZLA302_1
(CARBONIC ANHYDRASE 4)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		10 / 10 GLN A 121
HIS A 123
HIS A 125
HIS A 142
VAL A 144
VAL A 154
LEU A 214
THR A 215
THR A 216
TRP A 225
 MLT  A   3 (-3.9A)
ZN  A   1 ( 3.2A)
ZN  A   1 (-3.3A)
ZN  A   1 ( 3.2A)
None
MLT  A   3 (-4.6A)
MLT  A   3 ( 4.2A)
MLT  A   3 ( 4.3A)
MLT  A   3 (-2.8A)
MLT  A   3 (-4.9A)
 0.41A 5jn9A-3q31A:
24.3		 5jn9A-3q31A:
30.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JN9_A_EZLA302_1
(CARBONIC ANHYDRASE 4)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		6 / 10 HIS A 123
HIS A 125
VAL A 144
LEU A 214
THR A 215
THR A 216
 ZN  A   1 ( 3.2A)
ZN  A   1 (-3.3A)
None
MLT  A   3 ( 4.2A)
MLT  A   3 ( 4.3A)
MLT  A   3 (-2.8A)
 1.21A 5jn9A-3q31A:
24.3		 5jn9A-3q31A:
30.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JN9_A_EZLA302_1
(CARBONIC ANHYDRASE 4)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		7 / 10 HIS A 123
HIS A 142
VAL A 154
LEU A 214
THR A 215
THR A 216
TRP A 225
 ZN  A   1 ( 3.2A)
ZN  A   1 ( 3.2A)
MLT  A   3 (-4.6A)
MLT  A   3 ( 4.2A)
MLT  A   3 ( 4.3A)
MLT  A   3 (-2.8A)
MLT  A   3 (-4.9A)
 1.45A 5jn9A-3q31A:
24.3		 5jn9A-3q31A:
30.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JN9_A_EZLA302_1
(CARBONIC ANHYDRASE 4)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		5 / 10 HIS A 125
HIS A 123
VAL A 144
LEU A 214
THR A 215
 ZN  A   1 (-3.3A)
ZN  A   1 ( 3.2A)
None
MLT  A   3 ( 4.2A)
MLT  A   3 ( 4.3A)
 1.41A 5jn9A-3q31A:
24.3		 5jn9A-3q31A:
30.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JN9_A_EZLA302_1
(CARBONIC ANHYDRASE 4)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		5 / 10 HIS A 142
HIS A 125
VAL A 154
LEU A 214
THR A 216
 ZN  A   1 ( 3.2A)
ZN  A   1 (-3.3A)
MLT  A   3 (-4.6A)
MLT  A   3 ( 4.2A)
MLT  A   3 (-2.8A)
 1.44A 5jn9A-3q31A:
24.3		 5jn9A-3q31A:
30.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JN9_B_EZLB302_1
(CARBONIC ANHYDRASE 4)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		6 / 10 GLN A 102
HIS A 123
HIS A 125
HIS A 142
THR A 215
THR A 216
 None
ZN  A   1 ( 3.2A)
ZN  A   1 (-3.3A)
ZN  A   1 ( 3.2A)
MLT  A   3 ( 4.3A)
MLT  A   3 (-2.8A)
 1.07A 5jn9B-3q31A:
24.5		 5jn9B-3q31A:
30.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JN9_B_EZLB302_1
(CARBONIC ANHYDRASE 4)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		6 / 10 GLN A 102
HIS A 123
HIS A 125
VAL A 144
THR A 215
THR A 216
 None
ZN  A   1 ( 3.2A)
ZN  A   1 (-3.3A)
None
MLT  A   3 ( 4.3A)
MLT  A   3 (-2.8A)
 1.23A 5jn9B-3q31A:
24.5		 5jn9B-3q31A:
30.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JN9_B_EZLB302_1
(CARBONIC ANHYDRASE 4)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		10 / 10 GLN A 121
HIS A 123
HIS A 125
HIS A 142
VAL A 144
VAL A 154
LEU A 214
THR A 215
THR A 216
TRP A 225
 MLT  A   3 (-3.9A)
ZN  A   1 ( 3.2A)
ZN  A   1 (-3.3A)
ZN  A   1 ( 3.2A)
None
MLT  A   3 (-4.6A)
MLT  A   3 ( 4.2A)
MLT  A   3 ( 4.3A)
MLT  A   3 (-2.8A)
MLT  A   3 (-4.9A)
 0.43A 5jn9B-3q31A:
24.5		 5jn9B-3q31A:
30.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JN9_B_EZLB302_1
(CARBONIC ANHYDRASE 4)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		6 / 10 HIS A 123
HIS A 125
VAL A 144
LEU A 214
THR A 215
THR A 216
 ZN  A   1 ( 3.2A)
ZN  A   1 (-3.3A)
None
MLT  A   3 ( 4.2A)
MLT  A   3 ( 4.3A)
MLT  A   3 (-2.8A)
 1.22A 5jn9B-3q31A:
24.5		 5jn9B-3q31A:
30.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JN9_B_EZLB302_1
(CARBONIC ANHYDRASE 4)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		7 / 10 HIS A 123
HIS A 142
VAL A 154
LEU A 214
THR A 215
THR A 216
TRP A 225
 ZN  A   1 ( 3.2A)
ZN  A   1 ( 3.2A)
MLT  A   3 (-4.6A)
MLT  A   3 ( 4.2A)
MLT  A   3 ( 4.3A)
MLT  A   3 (-2.8A)
MLT  A   3 (-4.9A)
 1.42A 5jn9B-3q31A:
24.5		 5jn9B-3q31A:
30.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JN9_B_EZLB302_1
(CARBONIC ANHYDRASE 4)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		5 / 10 HIS A 125
HIS A 123
VAL A 144
LEU A 214
THR A 215
 ZN  A   1 (-3.3A)
ZN  A   1 ( 3.2A)
None
MLT  A   3 ( 4.2A)
MLT  A   3 ( 4.3A)
 1.44A 5jn9B-3q31A:
24.5		 5jn9B-3q31A:
30.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JN9_B_EZLB302_1
(CARBONIC ANHYDRASE 4)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		5 / 10 HIS A 142
HIS A 125
VAL A 154
LEU A 214
THR A 216
 ZN  A   1 ( 3.2A)
ZN  A   1 (-3.3A)
MLT  A   3 (-4.6A)
MLT  A   3 ( 4.2A)
MLT  A   3 (-2.8A)
 1.37A 5jn9B-3q31A:
24.5		 5jn9B-3q31A:
30.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JN9_C_EZLC302_1
(CARBONIC ANHYDRASE 4)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		5 / 9 GLN A 102
HIS A 123
HIS A 125
THR A 215
THR A 216
 None
ZN  A   1 ( 3.2A)
ZN  A   1 (-3.3A)
MLT  A   3 ( 4.3A)
MLT  A   3 (-2.8A)
 1.17A 5jn9C-3q31A:
24.2		 5jn9C-3q31A:
30.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JN9_C_EZLC302_1
(CARBONIC ANHYDRASE 4)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		9 / 9 GLN A 121
HIS A 123
HIS A 125
HIS A 142
VAL A 144
LEU A 214
THR A 215
THR A 216
TRP A 225
 MLT  A   3 (-3.9A)
ZN  A   1 ( 3.2A)
ZN  A   1 (-3.3A)
ZN  A   1 ( 3.2A)
None
MLT  A   3 ( 4.2A)
MLT  A   3 ( 4.3A)
MLT  A   3 (-2.8A)
MLT  A   3 (-4.9A)
 0.33A 5jn9C-3q31A:
24.2		 5jn9C-3q31A:
30.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JN9_C_EZLC302_1
(CARBONIC ANHYDRASE 4)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		5 / 9 HIS A 125
VAL A 154
LEU A 214
THR A 215
THR A 216
 ZN  A   1 (-3.3A)
MLT  A   3 (-4.6A)
MLT  A   3 ( 4.2A)
MLT  A   3 ( 4.3A)
MLT  A   3 (-2.8A)
 0.98A 5jn9C-3q31A:
24.2		 5jn9C-3q31A:
30.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JN9_C_EZLC302_1
(CARBONIC ANHYDRASE 4)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		5 / 9 HIS A 142
HIS A 125
VAL A 154
LEU A 214
THR A 216
 ZN  A   1 ( 3.2A)
ZN  A   1 (-3.3A)
MLT  A   3 (-4.6A)
MLT  A   3 ( 4.2A)
MLT  A   3 (-2.8A)
 1.40A 5jn9C-3q31A:
24.2		 5jn9C-3q31A:
30.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JN9_D_EZLD302_1
(CARBONIC ANHYDRASE 4)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		6 / 10 GLN A 102
HIS A 123
HIS A 125
HIS A 142
THR A 215
THR A 216
 None
ZN  A   1 ( 3.2A)
ZN  A   1 (-3.3A)
ZN  A   1 ( 3.2A)
MLT  A   3 ( 4.3A)
MLT  A   3 (-2.8A)
 1.13A 5jn9D-3q31A:
24.0		 5jn9D-3q31A:
30.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JN9_D_EZLD302_1
(CARBONIC ANHYDRASE 4)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		5 / 10 GLN A 102
HIS A 125
VAL A 144
THR A 215
THR A 216
 None
ZN  A   1 (-3.3A)
None
MLT  A   3 ( 4.3A)
MLT  A   3 (-2.8A)
 1.21A 5jn9D-3q31A:
24.0		 5jn9D-3q31A:
30.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JN9_D_EZLD302_1
(CARBONIC ANHYDRASE 4)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		10 / 10 GLN A 121
HIS A 123
HIS A 125
HIS A 142
VAL A 144
VAL A 154
LEU A 214
THR A 215
THR A 216
TRP A 225
 MLT  A   3 (-3.9A)
ZN  A   1 ( 3.2A)
ZN  A   1 (-3.3A)
ZN  A   1 ( 3.2A)
None
MLT  A   3 (-4.6A)
MLT  A   3 ( 4.2A)
MLT  A   3 ( 4.3A)
MLT  A   3 (-2.8A)
MLT  A   3 (-4.9A)
 0.34A 5jn9D-3q31A:
24.0		 5jn9D-3q31A:
30.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JN9_D_EZLD302_1
(CARBONIC ANHYDRASE 4)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		7 / 10 HIS A 123
HIS A 142
VAL A 154
LEU A 214
THR A 215
THR A 216
TRP A 225
 ZN  A   1 ( 3.2A)
ZN  A   1 ( 3.2A)
MLT  A   3 (-4.6A)
MLT  A   3 ( 4.2A)
MLT  A   3 ( 4.3A)
MLT  A   3 (-2.8A)
MLT  A   3 (-4.9A)
 1.45A 5jn9D-3q31A:
24.0		 5jn9D-3q31A:
30.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JN9_D_EZLD302_1
(CARBONIC ANHYDRASE 4)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		5 / 10 HIS A 125
HIS A 123
VAL A 144
LEU A 214
THR A 215
 ZN  A   1 (-3.3A)
ZN  A   1 ( 3.2A)
None
MLT  A   3 ( 4.2A)
MLT  A   3 ( 4.3A)
 1.37A 5jn9D-3q31A:
24.0		 5jn9D-3q31A:
30.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JN9_D_EZLD302_1
(CARBONIC ANHYDRASE 4)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		5 / 10 HIS A 142
HIS A 125
VAL A 154
LEU A 214
THR A 216
 ZN  A   1 ( 3.2A)
ZN  A   1 (-3.3A)
MLT  A   3 (-4.6A)
MLT  A   3 ( 4.2A)
MLT  A   3 (-2.8A)
 1.45A 5jn9D-3q31A:
24.0		 5jn9D-3q31A:
30.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JNA_A_TORA302_1
(CARBONIC ANHYDRASE 4)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		7 / 12 GLN A 102
HIS A 123
HIS A 125
GLU A 129
HIS A 142
THR A 215
THR A 216
 None
ZN  A   1 ( 3.2A)
ZN  A   1 (-3.3A)
ZN  A   1 ( 4.7A)
ZN  A   1 ( 3.2A)
MLT  A   3 ( 4.3A)
MLT  A   3 (-2.8A)
 1.03A 5jnaA-3q31A:
24.2		 5jnaA-3q31A:
30.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JNA_A_TORA302_1
(CARBONIC ANHYDRASE 4)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		6 / 12 GLN A 102
HIS A 123
HIS A 125
VAL A 144
THR A 215
THR A 216
 None
ZN  A   1 ( 3.2A)
ZN  A   1 (-3.3A)
None
MLT  A   3 ( 4.3A)
MLT  A   3 (-2.8A)
 1.19A 5jnaA-3q31A:
24.2		 5jnaA-3q31A:
30.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JNA_A_TORA302_1
(CARBONIC ANHYDRASE 4)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		10 / 12 GLN A 121
HIS A 123
HIS A 125
GLU A 129
HIS A 142
VAL A 144
VAL A 154
LEU A 214
THR A 215
THR A 216
 MLT  A   3 (-3.9A)
ZN  A   1 ( 3.2A)
ZN  A   1 (-3.3A)
ZN  A   1 ( 4.7A)
ZN  A   1 ( 3.2A)
None
MLT  A   3 (-4.6A)
MLT  A   3 ( 4.2A)
MLT  A   3 ( 4.3A)
MLT  A   3 (-2.8A)
 0.54A 5jnaA-3q31A:
24.2		 5jnaA-3q31A:
30.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JNA_A_TORA302_1
(CARBONIC ANHYDRASE 4)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		6 / 12 HIS A 123
HIS A 125
VAL A 144
LEU A 214
THR A 215
THR A 216
 ZN  A   1 ( 3.2A)
ZN  A   1 (-3.3A)
None
MLT  A   3 ( 4.2A)
MLT  A   3 ( 4.3A)
MLT  A   3 (-2.8A)
 1.20A 5jnaA-3q31A:
24.2		 5jnaA-3q31A:
30.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JNA_A_TORA302_1
(CARBONIC ANHYDRASE 4)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		6 / 12 HIS A 123
HIS A 142
VAL A 154
LEU A 214
THR A 215
THR A 216
 ZN  A   1 ( 3.2A)
ZN  A   1 ( 3.2A)
MLT  A   3 (-4.6A)
MLT  A   3 ( 4.2A)
MLT  A   3 ( 4.3A)
MLT  A   3 (-2.8A)
 1.45A 5jnaA-3q31A:
24.2		 5jnaA-3q31A:
30.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JNA_A_TORA302_1
(CARBONIC ANHYDRASE 4)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		6 / 12 HIS A 125
GLU A 129
VAL A 154
LEU A 214
THR A 215
THR A 216
 ZN  A   1 (-3.3A)
ZN  A   1 ( 4.7A)
MLT  A   3 (-4.6A)
MLT  A   3 ( 4.2A)
MLT  A   3 ( 4.3A)
MLT  A   3 (-2.8A)
 0.99A 5jnaA-3q31A:
24.2		 5jnaA-3q31A:
30.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JNA_B_TORB302_1
(CARBONIC ANHYDRASE 4)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		6 / 12 GLN A 102
HIS A 123
HIS A 125
HIS A 142
THR A 215
THR A 216
 None
ZN  A   1 ( 3.2A)
ZN  A   1 (-3.3A)
ZN  A   1 ( 3.2A)
MLT  A   3 ( 4.3A)
MLT  A   3 (-2.8A)
 1.04A 5jnaB-3q31A:
24.3		 5jnaB-3q31A:
30.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JNA_B_TORB302_1
(CARBONIC ANHYDRASE 4)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		6 / 12 GLN A 102
HIS A 123
HIS A 125
VAL A 144
THR A 215
THR A 216
 None
ZN  A   1 ( 3.2A)
ZN  A   1 (-3.3A)
None
MLT  A   3 ( 4.3A)
MLT  A   3 (-2.8A)
 1.21A 5jnaB-3q31A:
24.3		 5jnaB-3q31A:
30.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JNA_B_TORB302_1
(CARBONIC ANHYDRASE 4)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		10 / 12 GLN A 121
HIS A 123
HIS A 125
HIS A 142
VAL A 144
VAL A 154
LEU A 214
THR A 215
THR A 216
TRP A 225
 MLT  A   3 (-3.9A)
ZN  A   1 ( 3.2A)
ZN  A   1 (-3.3A)
ZN  A   1 ( 3.2A)
None
MLT  A   3 (-4.6A)
MLT  A   3 ( 4.2A)
MLT  A   3 ( 4.3A)
MLT  A   3 (-2.8A)
MLT  A   3 (-4.9A)
 0.51A 5jnaB-3q31A:
24.3		 5jnaB-3q31A:
30.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JNA_B_TORB302_1
(CARBONIC ANHYDRASE 4)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		6 / 12 HIS A 123
HIS A 125
VAL A 144
LEU A 214
THR A 215
THR A 216
 ZN  A   1 ( 3.2A)
ZN  A   1 (-3.3A)
None
MLT  A   3 ( 4.2A)
MLT  A   3 ( 4.3A)
MLT  A   3 (-2.8A)
 1.20A 5jnaB-3q31A:
24.3		 5jnaB-3q31A:
30.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JNA_B_TORB302_1
(CARBONIC ANHYDRASE 4)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		7 / 12 HIS A 123
HIS A 142
VAL A 154
LEU A 214
THR A 215
THR A 216
TRP A 225
 ZN  A   1 ( 3.2A)
ZN  A   1 ( 3.2A)
MLT  A   3 (-4.6A)
MLT  A   3 ( 4.2A)
MLT  A   3 ( 4.3A)
MLT  A   3 (-2.8A)
MLT  A   3 (-4.9A)
 1.43A 5jnaB-3q31A:
24.3		 5jnaB-3q31A:
30.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JNA_B_TORB302_1
(CARBONIC ANHYDRASE 4)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		5 / 12 HIS A 125
HIS A 123
VAL A 144
LEU A 214
THR A 215
 ZN  A   1 (-3.3A)
ZN  A   1 ( 3.2A)
None
MLT  A   3 ( 4.2A)
MLT  A   3 ( 4.3A)
 1.36A 5jnaB-3q31A:
24.3		 5jnaB-3q31A:
30.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JNA_C_TORC302_1
(CARBONIC ANHYDRASE 4)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		6 / 11 GLN A 102
HIS A 123
HIS A 125
HIS A 142
THR A 215
THR A 216
 None
ZN  A   1 ( 3.2A)
ZN  A   1 (-3.3A)
ZN  A   1 ( 3.2A)
MLT  A   3 ( 4.3A)
MLT  A   3 (-2.8A)
 1.05A 5jnaC-3q31A:
24.0		 5jnaC-3q31A:
30.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JNA_C_TORC302_1
(CARBONIC ANHYDRASE 4)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		6 / 11 GLN A 102
HIS A 123
HIS A 125
VAL A 144
THR A 215
THR A 216
 None
ZN  A   1 ( 3.2A)
ZN  A   1 (-3.3A)
None
MLT  A   3 ( 4.3A)
MLT  A   3 (-2.8A)
 1.19A 5jnaC-3q31A:
24.0		 5jnaC-3q31A:
30.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JNA_C_TORC302_1
(CARBONIC ANHYDRASE 4)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		9 / 11 GLN A 121
HIS A 123
HIS A 125
HIS A 142
VAL A 144
VAL A 154
LEU A 214
THR A 215
THR A 216
 MLT  A   3 (-3.9A)
ZN  A   1 ( 3.2A)
ZN  A   1 (-3.3A)
ZN  A   1 ( 3.2A)
None
MLT  A   3 (-4.6A)
MLT  A   3 ( 4.2A)
MLT  A   3 ( 4.3A)
MLT  A   3 (-2.8A)
 0.56A 5jnaC-3q31A:
24.0		 5jnaC-3q31A:
30.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JNA_C_TORC302_1
(CARBONIC ANHYDRASE 4)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		6 / 11 HIS A 123
HIS A 125
VAL A 144
LEU A 214
THR A 215
THR A 216
 ZN  A   1 ( 3.2A)
ZN  A   1 (-3.3A)
None
MLT  A   3 ( 4.2A)
MLT  A   3 ( 4.3A)
MLT  A   3 (-2.8A)
 1.20A 5jnaC-3q31A:
24.0		 5jnaC-3q31A:
30.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JNA_C_TORC302_1
(CARBONIC ANHYDRASE 4)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		6 / 11 HIS A 123
HIS A 142
VAL A 154
LEU A 214
THR A 215
THR A 216
 ZN  A   1 ( 3.2A)
ZN  A   1 ( 3.2A)
MLT  A   3 (-4.6A)
MLT  A   3 ( 4.2A)
MLT  A   3 ( 4.3A)
MLT  A   3 (-2.8A)
 1.45A 5jnaC-3q31A:
24.0		 5jnaC-3q31A:
30.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JNA_D_TORD302_1
(CARBONIC ANHYDRASE 4)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		6 / 12 GLN A 102
HIS A 123
HIS A 125
HIS A 142
THR A 215
THR A 216
 None
ZN  A   1 ( 3.2A)
ZN  A   1 (-3.3A)
ZN  A   1 ( 3.2A)
MLT  A   3 ( 4.3A)
MLT  A   3 (-2.8A)
 1.04A 5jnaD-3q31A:
24.0		 5jnaD-3q31A:
30.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JNA_D_TORD302_1
(CARBONIC ANHYDRASE 4)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		6 / 12 GLN A 102
HIS A 123
HIS A 125
VAL A 144
THR A 215
THR A 216
 None
ZN  A   1 ( 3.2A)
ZN  A   1 (-3.3A)
None
MLT  A   3 ( 4.3A)
MLT  A   3 (-2.8A)
 1.18A 5jnaD-3q31A:
24.0		 5jnaD-3q31A:
30.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JNA_D_TORD302_1
(CARBONIC ANHYDRASE 4)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		10 / 12 GLN A 121
HIS A 123
HIS A 125
HIS A 142
VAL A 144
VAL A 154
LEU A 214
THR A 215
THR A 216
TRP A 225
 MLT  A   3 (-3.9A)
ZN  A   1 ( 3.2A)
ZN  A   1 (-3.3A)
ZN  A   1 ( 3.2A)
None
MLT  A   3 (-4.6A)
MLT  A   3 ( 4.2A)
MLT  A   3 ( 4.3A)
MLT  A   3 (-2.8A)
MLT  A   3 (-4.9A)
 0.47A 5jnaD-3q31A:
24.0		 5jnaD-3q31A:
30.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JNA_D_TORD302_1
(CARBONIC ANHYDRASE 4)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		6 / 12 HIS A 123
HIS A 125
VAL A 144
LEU A 214
THR A 215
THR A 216
 ZN  A   1 ( 3.2A)
ZN  A   1 (-3.3A)
None
MLT  A   3 ( 4.2A)
MLT  A   3 ( 4.3A)
MLT  A   3 (-2.8A)
 1.16A 5jnaD-3q31A:
24.0		 5jnaD-3q31A:
30.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JNA_D_TORD302_1
(CARBONIC ANHYDRASE 4)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		7 / 12 HIS A 123
HIS A 142
VAL A 154
LEU A 214
THR A 215
THR A 216
TRP A 225
 ZN  A   1 ( 3.2A)
ZN  A   1 ( 3.2A)
MLT  A   3 (-4.6A)
MLT  A   3 ( 4.2A)
MLT  A   3 ( 4.3A)
MLT  A   3 (-2.8A)
MLT  A   3 (-4.9A)
 1.41A 5jnaD-3q31A:
24.0		 5jnaD-3q31A:
30.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JNC_A_6LHA302_0
(CARBONIC ANHYDRASE 4)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		7 / 11 GLN A 102
HIS A 123
HIS A 125
GLU A 129
HIS A 142
THR A 215
THR A 216
 None
ZN  A   1 ( 3.2A)
ZN  A   1 (-3.3A)
ZN  A   1 ( 4.7A)
ZN  A   1 ( 3.2A)
MLT  A   3 ( 4.3A)
MLT  A   3 (-2.8A)
 1.07A 5jncA-3q31A:
24.3		 5jncA-3q31A:
30.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JNC_A_6LHA302_0
(CARBONIC ANHYDRASE 4)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		6 / 11 GLN A 102
HIS A 123
HIS A 125
VAL A 144
THR A 215
THR A 216
 None
ZN  A   1 ( 3.2A)
ZN  A   1 (-3.3A)
None
MLT  A   3 ( 4.3A)
MLT  A   3 (-2.8A)
 1.24A 5jncA-3q31A:
24.3		 5jncA-3q31A:
30.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JNC_A_6LHA302_0
(CARBONIC ANHYDRASE 4)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		5 / 11 GLN A 121
HIS A 123
GLU A 140
VAL A 144
THR A 215
 MLT  A   3 (-3.9A)
ZN  A   1 ( 3.2A)
None
None
MLT  A   3 ( 4.3A)
 1.29A 5jncA-3q31A:
24.3		 5jncA-3q31A:
30.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JNC_A_6LHA302_0
(CARBONIC ANHYDRASE 4)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		11 / 11 GLN A 121
HIS A 123
HIS A 125
GLU A 129
HIS A 142
VAL A 144
VAL A 154
LEU A 214
THR A 215
THR A 216
TRP A 225
 MLT  A   3 (-3.9A)
ZN  A   1 ( 3.2A)
ZN  A   1 (-3.3A)
ZN  A   1 ( 4.7A)
ZN  A   1 ( 3.2A)
None
MLT  A   3 (-4.6A)
MLT  A   3 ( 4.2A)
MLT  A   3 ( 4.3A)
MLT  A   3 (-2.8A)
MLT  A   3 (-4.9A)
 0.42A 5jncA-3q31A:
24.3		 5jncA-3q31A:
30.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JNC_A_6LHA302_0
(CARBONIC ANHYDRASE 4)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		6 / 11 HIS A 123
HIS A 125
VAL A 144
LEU A 214
THR A 215
THR A 216
 ZN  A   1 ( 3.2A)
ZN  A   1 (-3.3A)
None
MLT  A   3 ( 4.2A)
MLT  A   3 ( 4.3A)
MLT  A   3 (-2.8A)
 1.22A 5jncA-3q31A:
24.3		 5jncA-3q31A:
30.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JNC_A_6LHA302_0
(CARBONIC ANHYDRASE 4)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		7 / 11 HIS A 123
HIS A 142
VAL A 154
LEU A 214
THR A 215
THR A 216
TRP A 225
 ZN  A   1 ( 3.2A)
ZN  A   1 ( 3.2A)
MLT  A   3 (-4.6A)
MLT  A   3 ( 4.2A)
MLT  A   3 ( 4.3A)
MLT  A   3 (-2.8A)
MLT  A   3 (-4.9A)
 1.44A 5jncA-3q31A:
24.3		 5jncA-3q31A:
30.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JNC_A_6LHA302_0
(CARBONIC ANHYDRASE 4)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		6 / 11 HIS A 125
GLU A 129
VAL A 154
LEU A 214
THR A 215
THR A 216
 ZN  A   1 (-3.3A)
ZN  A   1 ( 4.7A)
MLT  A   3 (-4.6A)
MLT  A   3 ( 4.2A)
MLT  A   3 ( 4.3A)
MLT  A   3 (-2.8A)
 0.99A 5jncA-3q31A:
24.3		 5jncA-3q31A:
30.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JNC_B_6LHB302_0
(CARBONIC ANHYDRASE 4)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		6 / 10 GLN A 102
HIS A 123
HIS A 125
HIS A 142
THR A 215
THR A 216
 None
ZN  A   1 ( 3.2A)
ZN  A   1 (-3.3A)
ZN  A   1 ( 3.2A)
MLT  A   3 ( 4.3A)
MLT  A   3 (-2.8A)
 1.13A 5jncB-3q31A:
24.4		 5jncB-3q31A:
30.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JNC_B_6LHB302_0
(CARBONIC ANHYDRASE 4)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		5 / 10 GLN A 102
HIS A 125
VAL A 144
THR A 215
THR A 216
 None
ZN  A   1 (-3.3A)
None
MLT  A   3 ( 4.3A)
MLT  A   3 (-2.8A)
 1.21A 5jncB-3q31A:
24.4		 5jncB-3q31A:
30.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JNC_B_6LHB302_0
(CARBONIC ANHYDRASE 4)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		10 / 10 GLN A 121
HIS A 123
HIS A 125
HIS A 142
VAL A 144
VAL A 154
LEU A 214
THR A 215
THR A 216
TRP A 225
 MLT  A   3 (-3.9A)
ZN  A   1 ( 3.2A)
ZN  A   1 (-3.3A)
ZN  A   1 ( 3.2A)
None
MLT  A   3 (-4.6A)
MLT  A   3 ( 4.2A)
MLT  A   3 ( 4.3A)
MLT  A   3 (-2.8A)
MLT  A   3 (-4.9A)
 0.37A 5jncB-3q31A:
24.4		 5jncB-3q31A:
30.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JNC_B_6LHB302_0
(CARBONIC ANHYDRASE 4)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		7 / 10 HIS A 123
HIS A 142
VAL A 154
LEU A 214
THR A 215
THR A 216
TRP A 225
 ZN  A   1 ( 3.2A)
ZN  A   1 ( 3.2A)
MLT  A   3 (-4.6A)
MLT  A   3 ( 4.2A)
MLT  A   3 ( 4.3A)
MLT  A   3 (-2.8A)
MLT  A   3 (-4.9A)
 1.43A 5jncB-3q31A:
24.4		 5jncB-3q31A:
30.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JNC_B_6LHB302_0
(CARBONIC ANHYDRASE 4)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		5 / 10 HIS A 125
HIS A 123
VAL A 144
LEU A 214
THR A 215
 ZN  A   1 (-3.3A)
ZN  A   1 ( 3.2A)
None
MLT  A   3 ( 4.2A)
MLT  A   3 ( 4.3A)
 1.38A 5jncB-3q31A:
24.4		 5jncB-3q31A:
30.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JNC_B_6LHB302_0
(CARBONIC ANHYDRASE 4)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		6 / 10 HIS A 142
HIS A 125
VAL A 154
LEU A 214
THR A 215
THR A 216
 ZN  A   1 ( 3.2A)
ZN  A   1 (-3.3A)
MLT  A   3 (-4.6A)
MLT  A   3 ( 4.2A)
MLT  A   3 ( 4.3A)
MLT  A   3 (-2.8A)
 1.34A 5jncB-3q31A:
24.4		 5jncB-3q31A:
30.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JNC_C_6LHC302_0
(CARBONIC ANHYDRASE 4)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		6 / 9 GLN A 102
HIS A 123
HIS A 125
HIS A 142
THR A 215
THR A 216
 None
ZN  A   1 ( 3.2A)
ZN  A   1 (-3.3A)
ZN  A   1 ( 3.2A)
MLT  A   3 ( 4.3A)
MLT  A   3 (-2.8A)
 1.08A 5jncC-3q31A:
24.1		 5jncC-3q31A:
30.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JNC_C_6LHC302_0
(CARBONIC ANHYDRASE 4)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		9 / 9 GLN A 121
HIS A 123
HIS A 125
HIS A 142
VAL A 144
LEU A 214
THR A 215
THR A 216
TRP A 225
 MLT  A   3 (-3.9A)
ZN  A   1 ( 3.2A)
ZN  A   1 (-3.3A)
ZN  A   1 ( 3.2A)
None
MLT  A   3 ( 4.2A)
MLT  A   3 ( 4.3A)
MLT  A   3 (-2.8A)
MLT  A   3 (-4.9A)
 0.35A 5jncC-3q31A:
24.1		 5jncC-3q31A:
30.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JNC_C_6LHC302_0
(CARBONIC ANHYDRASE 4)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		6 / 9 HIS A 123
HIS A 142
LEU A 214
THR A 215
THR A 216
TRP A 225
 ZN  A   1 ( 3.2A)
ZN  A   1 ( 3.2A)
MLT  A   3 ( 4.2A)
MLT  A   3 ( 4.3A)
MLT  A   3 (-2.8A)
MLT  A   3 (-4.9A)
 1.48A 5jncC-3q31A:
24.1		 5jncC-3q31A:
30.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JNC_C_6LHC302_0
(CARBONIC ANHYDRASE 4)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		5 / 9 HIS A 125
VAL A 154
LEU A 214
THR A 215
THR A 216
 ZN  A   1 (-3.3A)
MLT  A   3 (-4.6A)
MLT  A   3 ( 4.2A)
MLT  A   3 ( 4.3A)
MLT  A   3 (-2.8A)
 1.00A 5jncC-3q31A:
24.1		 5jncC-3q31A:
30.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JNC_C_6LHC302_0
(CARBONIC ANHYDRASE 4)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		5 / 9 HIS A 142
HIS A 125
VAL A 154
LEU A 214
THR A 216
 ZN  A   1 ( 3.2A)
ZN  A   1 (-3.3A)
MLT  A   3 (-4.6A)
MLT  A   3 ( 4.2A)
MLT  A   3 (-2.8A)
 1.40A 5jncC-3q31A:
24.1		 5jncC-3q31A:
30.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JNC_D_6LHD302_0
(CARBONIC ANHYDRASE 4)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		5 / 9 GLN A 102
HIS A 123
HIS A 125
THR A 215
THR A 216
 None
ZN  A   1 ( 3.2A)
ZN  A   1 (-3.3A)
MLT  A   3 ( 4.3A)
MLT  A   3 (-2.8A)
 1.15A 5jncD-3q31A:
24.0		 5jncD-3q31A:
30.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JNC_D_6LHD302_0
(CARBONIC ANHYDRASE 4)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		9 / 9 GLN A 121
HIS A 123
HIS A 125
HIS A 142
VAL A 144
LEU A 214
THR A 215
THR A 216
TRP A 225
 MLT  A   3 (-3.9A)
ZN  A   1 ( 3.2A)
ZN  A   1 (-3.3A)
ZN  A   1 ( 3.2A)
None
MLT  A   3 ( 4.2A)
MLT  A   3 ( 4.3A)
MLT  A   3 (-2.8A)
MLT  A   3 (-4.9A)
 0.31A 5jncD-3q31A:
24.0		 5jncD-3q31A:
30.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JNC_D_6LHD302_0
(CARBONIC ANHYDRASE 4)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		6 / 9 HIS A 123
HIS A 142
LEU A 214
THR A 215
THR A 216
TRP A 225
 ZN  A   1 ( 3.2A)
ZN  A   1 ( 3.2A)
MLT  A   3 ( 4.2A)
MLT  A   3 ( 4.3A)
MLT  A   3 (-2.8A)
MLT  A   3 (-4.9A)
 1.49A 5jncD-3q31A:
24.0		 5jncD-3q31A:
30.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JNC_D_6LHD302_0
(CARBONIC ANHYDRASE 4)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		5 / 9 HIS A 125
VAL A 154
LEU A 214
THR A 215
THR A 216
 ZN  A   1 (-3.3A)
MLT  A   3 (-4.6A)
MLT  A   3 ( 4.2A)
MLT  A   3 ( 4.3A)
MLT  A   3 (-2.8A)
 1.00A 5jncD-3q31A:
24.0		 5jncD-3q31A:
30.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JNC_D_6LHD302_0
(CARBONIC ANHYDRASE 4)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		5 / 9 HIS A 142
HIS A 125
VAL A 154
LEU A 214
THR A 216
 ZN  A   1 ( 3.2A)
ZN  A   1 (-3.3A)
MLT  A   3 (-4.6A)
MLT  A   3 ( 4.2A)
MLT  A   3 (-2.8A)
 1.41A 5jncD-3q31A:
24.0		 5jncD-3q31A:
30.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JWA_A_ACTA612_0
(NADH DEHYDROGENASE,
PUTATIVE)		 4eae LMO1068 PROTEIN
(Listeria
monocytogenes) 		3 / 3 LYS A 193
ASP A 195
ARG A 265
 None
MLT  A 301 ( 4.9A)
None
 1.10A 5jwaA-4eaeA:
undetectable
5jwaH-4eaeA:
undetectable		 5jwaA-4eaeA:
19.02
5jwaH-4eaeA:
19.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KPC_B_SAMB401_0
(PAVINE
N-METHYLTRANSFERASE)		 5ikm NS5 METHYL
TRANSFERASE
(Dengue
virus) 		5 / 12 GLY A  81
GLY A  83
SER A 128
ASP A 131
VAL A 132
 SAM  A 311 (-3.2A)
SAM  A 311 (-3.3A)
None
MLT  A 313 ( 2.6A)
SAM  A 311 (-3.7A)
 1.00A 5kpcB-5ikmA:
8.3		 5kpcB-5ikmA:
18.69
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5KQR_A_SAMA301_0
(METHYLTRANSFERASE)		 5ikm NS5 METHYL
TRANSFERASE
(Dengue
virus) 		10 / 12 GLY A  58
GLY A  81
GLY A  83
GLY A  86
TRP A  87
THR A 104
HIS A 110
ASP A 131
VAL A 132
ILE A 147
 SAM  A 311 (-3.3A)
SAM  A 311 (-3.2A)
SAM  A 311 (-3.3A)
SAM  A 311 (-3.3A)
SAM  A 311 (-3.5A)
SAM  A 311 (-4.5A)
SAM  A 311 (-4.1A)
MLT  A 313 ( 2.6A)
SAM  A 311 (-3.7A)
SAM  A 311 ( 4.3A)
 0.20A 5kqrA-5ikmA:
41.8		 5kqrA-5ikmA:
62.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5KQS_A_SAMA307_0
(GENOME POLYPROTEIN)		 5ikm NS5 METHYL
TRANSFERASE
(Dengue
virus) 		11 / 12 GLY A  58
GLY A  81
GLY A  83
GLY A  86
TRP A  87
THR A 104
HIS A 110
ASP A 131
VAL A 132
ASP A 146
ILE A 147
 SAM  A 311 (-3.3A)
SAM  A 311 (-3.2A)
SAM  A 311 (-3.3A)
SAM  A 311 (-3.3A)
SAM  A 311 (-3.5A)
SAM  A 311 (-4.5A)
SAM  A 311 (-4.1A)
MLT  A 313 ( 2.6A)
SAM  A 311 (-3.7A)
SAM  A 311 (-3.8A)
SAM  A 311 ( 4.3A)
 0.31A 5kqsA-5ikmA:
41.8		 5kqsA-5ikmA:
62.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5KU6_A_MZMA301_1
(CARBONIC ANHYDRASE 4)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		6 / 10 GLN A 102
HIS A 123
HIS A 125
HIS A 142
THR A 215
THR A 216
 None
ZN  A   1 ( 3.2A)
ZN  A   1 (-3.3A)
ZN  A   1 ( 3.2A)
MLT  A   3 ( 4.3A)
MLT  A   3 (-2.8A)
 1.08A 5ku6A-3q31A:
24.3		 5ku6A-3q31A:
30.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5KU6_A_MZMA301_1
(CARBONIC ANHYDRASE 4)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		6 / 10 GLN A 102
HIS A 123
HIS A 125
VAL A 144
THR A 215
THR A 216
 None
ZN  A   1 ( 3.2A)
ZN  A   1 (-3.3A)
None
MLT  A   3 ( 4.3A)
MLT  A   3 (-2.8A)
 1.24A 5ku6A-3q31A:
24.3		 5ku6A-3q31A:
30.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5KU6_A_MZMA301_1
(CARBONIC ANHYDRASE 4)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		5 / 10 GLN A 102
HIS A 123
HIS A 125
VAL A 144
THR A 216
 None
ZN  A   1 ( 3.2A)
ZN  A   1 (-3.3A)
None
MLT  A   3 (-2.8A)
 1.46A 5ku6A-3q31A:
24.3		 5ku6A-3q31A:
30.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5KU6_A_MZMA301_1
(CARBONIC ANHYDRASE 4)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		10 / 10 GLN A 121
HIS A 123
HIS A 125
HIS A 142
VAL A 144
VAL A 154
LEU A 214
THR A 215
THR A 216
TRP A 225
 MLT  A   3 (-3.9A)
ZN  A   1 ( 3.2A)
ZN  A   1 (-3.3A)
ZN  A   1 ( 3.2A)
None
MLT  A   3 (-4.6A)
MLT  A   3 ( 4.2A)
MLT  A   3 ( 4.3A)
MLT  A   3 (-2.8A)
MLT  A   3 (-4.9A)
 0.40A 5ku6A-3q31A:
24.3		 5ku6A-3q31A:
30.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5KU6_A_MZMA301_1
(CARBONIC ANHYDRASE 4)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		6 / 10 HIS A 123
HIS A 125
VAL A 144
LEU A 214
THR A 215
THR A 216
 ZN  A   1 ( 3.2A)
ZN  A   1 (-3.3A)
None
MLT  A   3 ( 4.2A)
MLT  A   3 ( 4.3A)
MLT  A   3 (-2.8A)
 1.20A 5ku6A-3q31A:
24.3		 5ku6A-3q31A:
30.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5KU6_A_MZMA301_1
(CARBONIC ANHYDRASE 4)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		7 / 10 HIS A 123
HIS A 142
VAL A 154
LEU A 214
THR A 215
THR A 216
TRP A 225
 ZN  A   1 ( 3.2A)
ZN  A   1 ( 3.2A)
MLT  A   3 (-4.6A)
MLT  A   3 ( 4.2A)
MLT  A   3 ( 4.3A)
MLT  A   3 (-2.8A)
MLT  A   3 (-4.9A)
 1.43A 5ku6A-3q31A:
24.3		 5ku6A-3q31A:
30.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5KU6_A_MZMA301_1
(CARBONIC ANHYDRASE 4)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		5 / 10 HIS A 125
HIS A 123
VAL A 144
LEU A 214
THR A 215
 ZN  A   1 (-3.3A)
ZN  A   1 ( 3.2A)
None
MLT  A   3 ( 4.2A)
MLT  A   3 ( 4.3A)
 1.40A 5ku6A-3q31A:
24.3		 5ku6A-3q31A:
30.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5KU6_A_MZMA301_1
(CARBONIC ANHYDRASE 4)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		5 / 10 HIS A 142
HIS A 125
VAL A 154
LEU A 214
THR A 216
 ZN  A   1 ( 3.2A)
ZN  A   1 (-3.3A)
MLT  A   3 (-4.6A)
MLT  A   3 ( 4.2A)
MLT  A   3 (-2.8A)
 1.41A 5ku6A-3q31A:
24.3		 5ku6A-3q31A:
30.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5KU6_B_MZMB302_1
(CARBONIC ANHYDRASE 4)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		6 / 10 GLN A 102
HIS A 123
HIS A 125
HIS A 142
THR A 215
THR A 216
 None
ZN  A   1 ( 3.2A)
ZN  A   1 (-3.3A)
ZN  A   1 ( 3.2A)
MLT  A   3 ( 4.3A)
MLT  A   3 (-2.8A)
 1.08A 5ku6B-3q31A:
24.4		 5ku6B-3q31A:
30.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5KU6_B_MZMB302_1
(CARBONIC ANHYDRASE 4)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		5 / 10 GLN A 102
HIS A 125
VAL A 144
THR A 215
THR A 216
 None
ZN  A   1 (-3.3A)
None
MLT  A   3 ( 4.3A)
MLT  A   3 (-2.8A)
 1.22A 5ku6B-3q31A:
24.4		 5ku6B-3q31A:
30.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5KU6_B_MZMB302_1
(CARBONIC ANHYDRASE 4)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		10 / 10 GLN A 121
HIS A 123
HIS A 125
HIS A 142
VAL A 144
VAL A 154
LEU A 214
THR A 215
THR A 216
TRP A 225
 MLT  A   3 (-3.9A)
ZN  A   1 ( 3.2A)
ZN  A   1 (-3.3A)
ZN  A   1 ( 3.2A)
None
MLT  A   3 (-4.6A)
MLT  A   3 ( 4.2A)
MLT  A   3 ( 4.3A)
MLT  A   3 (-2.8A)
MLT  A   3 (-4.9A)
 0.37A 5ku6B-3q31A:
24.4		 5ku6B-3q31A:
30.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5KU6_B_MZMB302_1
(CARBONIC ANHYDRASE 4)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		7 / 10 HIS A 123
HIS A 142
VAL A 154
LEU A 214
THR A 215
THR A 216
TRP A 225
 ZN  A   1 ( 3.2A)
ZN  A   1 ( 3.2A)
MLT  A   3 (-4.6A)
MLT  A   3 ( 4.2A)
MLT  A   3 ( 4.3A)
MLT  A   3 (-2.8A)
MLT  A   3 (-4.9A)
 1.41A 5ku6B-3q31A:
24.4		 5ku6B-3q31A:
30.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5KU6_B_MZMB302_1
(CARBONIC ANHYDRASE 4)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		5 / 10 HIS A 125
HIS A 123
VAL A 144
LEU A 214
THR A 215
 ZN  A   1 (-3.3A)
ZN  A   1 ( 3.2A)
None
MLT  A   3 ( 4.2A)
MLT  A   3 ( 4.3A)
 1.39A 5ku6B-3q31A:
24.4		 5ku6B-3q31A:
30.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5KU6_B_MZMB302_1
(CARBONIC ANHYDRASE 4)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		5 / 10 HIS A 142
HIS A 125
VAL A 154
LEU A 214
THR A 216
 ZN  A   1 ( 3.2A)
ZN  A   1 (-3.3A)
MLT  A   3 (-4.6A)
MLT  A   3 ( 4.2A)
MLT  A   3 (-2.8A)
 1.38A 5ku6B-3q31A:
24.4		 5ku6B-3q31A:
30.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5KU6_C_MZMC301_1
(CARBONIC ANHYDRASE 4)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		6 / 9 GLN A 102
HIS A 123
HIS A 125
HIS A 142
THR A 215
THR A 216
 None
ZN  A   1 ( 3.2A)
ZN  A   1 (-3.3A)
ZN  A   1 ( 3.2A)
MLT  A   3 ( 4.3A)
MLT  A   3 (-2.8A)
 1.09A 5ku6C-3q31A:
24.1		 5ku6C-3q31A:
30.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5KU6_C_MZMC301_1
(CARBONIC ANHYDRASE 4)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		9 / 9 GLN A 121
HIS A 123
HIS A 125
HIS A 142
VAL A 144
LEU A 214
THR A 215
THR A 216
TRP A 225
 MLT  A   3 (-3.9A)
ZN  A   1 ( 3.2A)
ZN  A   1 (-3.3A)
ZN  A   1 ( 3.2A)
None
MLT  A   3 ( 4.2A)
MLT  A   3 ( 4.3A)
MLT  A   3 (-2.8A)
MLT  A   3 (-4.9A)
 0.35A 5ku6C-3q31A:
24.1		 5ku6C-3q31A:
30.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5KU6_C_MZMC301_1
(CARBONIC ANHYDRASE 4)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		6 / 9 HIS A 123
HIS A 142
LEU A 214
THR A 215
THR A 216
TRP A 225
 ZN  A   1 ( 3.2A)
ZN  A   1 ( 3.2A)
MLT  A   3 ( 4.2A)
MLT  A   3 ( 4.3A)
MLT  A   3 (-2.8A)
MLT  A   3 (-4.9A)
 1.44A 5ku6C-3q31A:
24.1		 5ku6C-3q31A:
30.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5KU6_C_MZMC301_1
(CARBONIC ANHYDRASE 4)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		5 / 9 HIS A 125
VAL A 154
LEU A 214
THR A 215
THR A 216
 ZN  A   1 (-3.3A)
MLT  A   3 (-4.6A)
MLT  A   3 ( 4.2A)
MLT  A   3 ( 4.3A)
MLT  A   3 (-2.8A)
 1.05A 5ku6C-3q31A:
24.1		 5ku6C-3q31A:
30.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5KU6_C_MZMC301_1
(CARBONIC ANHYDRASE 4)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		5 / 9 HIS A 142
HIS A 125
VAL A 154
LEU A 214
THR A 216
 ZN  A   1 ( 3.2A)
ZN  A   1 (-3.3A)
MLT  A   3 (-4.6A)
MLT  A   3 ( 4.2A)
MLT  A   3 (-2.8A)
 1.43A 5ku6C-3q31A:
24.1		 5ku6C-3q31A:
30.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5KU6_D_MZMD301_1
(CARBONIC ANHYDRASE 4)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		6 / 9 GLN A 102
HIS A 123
HIS A 125
HIS A 142
THR A 215
THR A 216
 None
ZN  A   1 ( 3.2A)
ZN  A   1 (-3.3A)
ZN  A   1 ( 3.2A)
MLT  A   3 ( 4.3A)
MLT  A   3 (-2.8A)
 1.09A 5ku6D-3q31A:
24.0		 5ku6D-3q31A:
30.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5KU6_D_MZMD301_1
(CARBONIC ANHYDRASE 4)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		9 / 9 GLN A 121
HIS A 123
HIS A 125
HIS A 142
VAL A 144
LEU A 214
THR A 215
THR A 216
TRP A 225
 MLT  A   3 (-3.9A)
ZN  A   1 ( 3.2A)
ZN  A   1 (-3.3A)
ZN  A   1 ( 3.2A)
None
MLT  A   3 ( 4.2A)
MLT  A   3 ( 4.3A)
MLT  A   3 (-2.8A)
MLT  A   3 (-4.9A)
 0.34A 5ku6D-3q31A:
24.0		 5ku6D-3q31A:
30.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5KU6_D_MZMD301_1
(CARBONIC ANHYDRASE 4)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		5 / 9 HIS A 125
VAL A 154
LEU A 214
THR A 215
THR A 216
 ZN  A   1 (-3.3A)
MLT  A   3 (-4.6A)
MLT  A   3 ( 4.2A)
MLT  A   3 ( 4.3A)
MLT  A   3 (-2.8A)
 1.02A 5ku6D-3q31A:
24.0		 5ku6D-3q31A:
30.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5KU6_D_MZMD301_1
(CARBONIC ANHYDRASE 4)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		5 / 9 HIS A 142
HIS A 125
VAL A 154
LEU A 214
THR A 216
 ZN  A   1 ( 3.2A)
ZN  A   1 (-3.3A)
MLT  A   3 (-4.6A)
MLT  A   3 ( 4.2A)
MLT  A   3 (-2.8A)
 1.39A 5ku6D-3q31A:
24.0		 5ku6D-3q31A:
30.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L5F_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA
TYPE-8,PROTEASOME
SUBUNIT BETA TYPE-5
PROTEASOME SUBUNIT
BETA
TYPE-6,PROTEASOME
SUBUNIT BETA
TYPE-1,PROTEASOME
SUBUNIT BETA
TYPE-6,PROTEASOME
SUBUNIT BETA
TYPE-1,PROTEASOME
SUBUNIT BETA TYPE-6)		 2g76 D-3-PHOSPHOGLYCERATE
DEHYDROGENASE
(Homo
sapiens) 		4 / 8 THR A  97
SER A  54
ALA A 285
SER A 286
 None
MLT  A 503 (-2.7A)
MLT  A 503 ( 3.3A)
None
 1.08A 5l5fY-2g76A:
undetectable
5l5fZ-2g76A:
undetectable		 5l5fY-2g76A:
23.66
5l5fZ-2g76A:
22.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LF7_V_6V8V303_0
(PROTEASOME SUBUNIT
BETA TYPE-3
PROTEASOME SUBUNIT
BETA TYPE-7)		 3g1p PROTEIN PHNP
(Escherichia
coli) 		5 / 11 ALA A  18
ALA A  13
GLY A  12
ASP A 228
LEU A 231
 ZN  A 300 ( 4.6A)
MLT  A 500 ( 3.8A)
None
None
None
 1.13A 5lf7V-3g1pA:
undetectable
5lf7W-3g1pA:
undetectable		 5lf7V-3g1pA:
20.46
5lf7W-3g1pA:
21.67
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5M5B_A_SAMA1001_0
(NS5
METHYLTRANSFERASE)		 5ikm NS5 METHYL
TRANSFERASE
(Dengue
virus) 		10 / 12 GLY A  58
GLY A  81
GLY A  83
GLY A  86
TRP A  87
THR A 104
HIS A 110
ASP A 131
VAL A 132
ILE A 147
 SAM  A 311 (-3.3A)
SAM  A 311 (-3.2A)
SAM  A 311 (-3.3A)
SAM  A 311 (-3.3A)
SAM  A 311 (-3.5A)
SAM  A 311 (-4.5A)
SAM  A 311 (-4.1A)
MLT  A 313 ( 2.6A)
SAM  A 311 (-3.7A)
SAM  A 311 ( 4.3A)
 0.32A 5m5bA-5ikmA:
41.9		 5m5bA-5ikmA:
60.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5M5B_A_SAMA1001_0
(NS5
METHYLTRANSFERASE)		 5ikm NS5 METHYL
TRANSFERASE
(Dengue
virus) 		10 / 12 GLY A  58
GLY A  81
GLY A  83
GLY A  86
TRP A  87
THR A 104
LYS A 105
ASP A 131
VAL A 132
ILE A 147
 SAM  A 311 (-3.3A)
SAM  A 311 (-3.2A)
SAM  A 311 (-3.3A)
SAM  A 311 (-3.3A)
SAM  A 311 (-3.5A)
SAM  A 311 (-4.5A)
MLT  A 313 ( 3.0A)
MLT  A 313 ( 2.6A)
SAM  A 311 (-3.7A)
SAM  A 311 ( 4.3A)
 0.71A 5m5bA-5ikmA:
41.9		 5m5bA-5ikmA:
60.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5M5B_A_SAMA1001_0
(NS5
METHYLTRANSFERASE)		 5ikm NS5 METHYL
TRANSFERASE
(Dengue
virus) 		8 / 12 GLY A  58
GLY A  83
GLY A  86
TRP A  87
THR A 104
HIS A 110
GLU A 111
ASP A 131
 SAM  A 311 (-3.3A)
SAM  A 311 (-3.3A)
SAM  A 311 (-3.3A)
SAM  A 311 (-3.5A)
SAM  A 311 (-4.5A)
SAM  A 311 (-4.1A)
None
MLT  A 313 ( 2.6A)
 0.76A 5m5bA-5ikmA:
41.9		 5m5bA-5ikmA:
60.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5M5B_A_SAMA1001_0
(NS5
METHYLTRANSFERASE)		 5ikm NS5 METHYL
TRANSFERASE
(Dengue
virus) 		8 / 12 GLY A  58
GLY A  83
GLY A  86
TRP A  87
THR A 104
LYS A 105
GLU A 111
ASP A 131
 SAM  A 311 (-3.3A)
SAM  A 311 (-3.3A)
SAM  A 311 (-3.3A)
SAM  A 311 (-3.5A)
SAM  A 311 (-4.5A)
MLT  A 313 ( 3.0A)
None
MLT  A 313 ( 2.6A)
 1.00A 5m5bA-5ikmA:
41.9		 5m5bA-5ikmA:
60.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M78_A_SALA304_1
(CARBONIC ANHYDRASE 2)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		6 / 7 GLN A 121
HIS A 123
VAL A 144
LEU A 214
THR A 215
THR A 216
 MLT  A   3 (-3.9A)
ZN  A   1 ( 3.2A)
None
MLT  A   3 ( 4.2A)
MLT  A   3 ( 4.3A)
MLT  A   3 (-2.8A)
 0.37A 5m78A-3q31A:
24.5		 5m78A-3q31A:
14.53
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5NJV_A_SAMA301_0
(NS5)		 5ikm NS5 METHYL
TRANSFERASE
(Dengue
virus) 		11 / 12 GLY A  58
GLY A  81
GLY A  83
GLY A  86
TRP A  87
THR A 104
HIS A 110
ASP A 131
VAL A 132
ASP A 146
ILE A 147
 SAM  A 311 (-3.3A)
SAM  A 311 (-3.2A)
SAM  A 311 (-3.3A)
SAM  A 311 (-3.3A)
SAM  A 311 (-3.5A)
SAM  A 311 (-4.5A)
SAM  A 311 (-4.1A)
MLT  A 313 ( 2.6A)
SAM  A 311 (-3.7A)
SAM  A 311 (-3.8A)
SAM  A 311 ( 4.3A)
 0.25A 5njvA-5ikmA:
41.2		 5njvA-5ikmA:
62.17
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5NJV_A_SAMA301_0
(NS5)		 5ikm NS5 METHYL
TRANSFERASE
(Dengue
virus) 		11 / 12 GLY A  58
GLY A  81
GLY A  83
GLY A  86
TRP A  87
THR A 104
LYS A 105
HIS A 110
ASP A 131
VAL A 132
ASP A 146
 SAM  A 311 (-3.3A)
SAM  A 311 (-3.2A)
SAM  A 311 (-3.3A)
SAM  A 311 (-3.3A)
SAM  A 311 (-3.5A)
SAM  A 311 (-4.5A)
MLT  A 313 ( 3.0A)
SAM  A 311 (-4.1A)
MLT  A 313 ( 2.6A)
SAM  A 311 (-3.7A)
SAM  A 311 (-3.8A)
 0.76A 5njvA-5ikmA:
41.2		 5njvA-5ikmA:
62.17
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5NJV_B_SAMB301_0
(NS5)		 5ikm NS5 METHYL
TRANSFERASE
(Dengue
virus) 		11 / 12 GLY A  58
GLY A  81
GLY A  83
GLY A  86
TRP A  87
THR A 104
HIS A 110
ASP A 131
VAL A 132
ASP A 146
ILE A 147
 SAM  A 311 (-3.3A)
SAM  A 311 (-3.2A)
SAM  A 311 (-3.3A)
SAM  A 311 (-3.3A)
SAM  A 311 (-3.5A)
SAM  A 311 (-4.5A)
SAM  A 311 (-4.1A)
MLT  A 313 ( 2.6A)
SAM  A 311 (-3.7A)
SAM  A 311 (-3.8A)
SAM  A 311 ( 4.3A)
 0.26A 5njvB-5ikmA:
41.6		 5njvB-5ikmA:
62.17
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5NJV_B_SAMB301_0
(NS5)		 5ikm NS5 METHYL
TRANSFERASE
(Dengue
virus) 		9 / 12 GLY A  58
GLY A  81
GLY A  83
GLY A  86
TRP A  87
THR A 104
LYS A 105
ASP A 131
VAL A 132
 SAM  A 311 (-3.3A)
SAM  A 311 (-3.2A)
SAM  A 311 (-3.3A)
SAM  A 311 (-3.3A)
SAM  A 311 (-3.5A)
SAM  A 311 (-4.5A)
MLT  A 313 ( 3.0A)
MLT  A 313 ( 2.6A)
SAM  A 311 (-3.7A)
 0.86A 5njvB-5ikmA:
41.6		 5njvB-5ikmA:
62.17
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5NJV_C_SAMC301_0
(NS5)		 5ikm NS5 METHYL
TRANSFERASE
(Dengue
virus) 		11 / 12 GLY A  58
GLY A  81
GLY A  83
GLY A  86
TRP A  87
THR A 104
LYS A 105
HIS A 110
VAL A 132
ASP A 146
ILE A 147
 SAM  A 311 (-3.3A)
SAM  A 311 (-3.2A)
SAM  A 311 (-3.3A)
SAM  A 311 (-3.3A)
SAM  A 311 (-3.5A)
SAM  A 311 (-4.5A)
MLT  A 313 ( 3.0A)
SAM  A 311 (-4.1A)
SAM  A 311 (-3.7A)
SAM  A 311 (-3.8A)
SAM  A 311 ( 4.3A)
 0.46A 5njvC-5ikmA:
40.3		 5njvC-5ikmA:
62.17
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5NJV_D_SAMD301_0
(NS5)		 5ikm NS5 METHYL
TRANSFERASE
(Dengue
virus) 		11 / 12 GLY A  58
GLY A  81
GLY A  83
TRP A  87
THR A 104
HIS A 110
GLU A 111
ASP A 131
VAL A 132
ASP A 146
ILE A 147
 SAM  A 311 (-3.3A)
SAM  A 311 (-3.2A)
SAM  A 311 (-3.3A)
SAM  A 311 (-3.5A)
SAM  A 311 (-4.5A)
SAM  A 311 (-4.1A)
None
MLT  A 313 ( 2.6A)
SAM  A 311 (-3.7A)
SAM  A 311 (-3.8A)
SAM  A 311 ( 4.3A)
 0.65A 5njvD-5ikmA:
39.8		 5njvD-5ikmA:
62.17
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5NJV_D_SAMD301_0
(NS5)		 5ikm NS5 METHYL
TRANSFERASE
(Dengue
virus) 		10 / 12 GLY A  58
GLY A  81
GLY A  83
TRP A  87
THR A 104
LYS A 105
HIS A 110
VAL A 132
ASP A 146
ILE A 147
 SAM  A 311 (-3.3A)
SAM  A 311 (-3.2A)
SAM  A 311 (-3.3A)
SAM  A 311 (-3.5A)
SAM  A 311 (-4.5A)
MLT  A 313 ( 3.0A)
SAM  A 311 (-4.1A)
SAM  A 311 (-3.7A)
SAM  A 311 (-3.8A)
SAM  A 311 ( 4.3A)
 0.65A 5njvD-5ikmA:
39.8		 5njvD-5ikmA:
62.17
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5NJV_D_SAMD301_0
(NS5)		 5ikm NS5 METHYL
TRANSFERASE
(Dengue
virus) 		6 / 12 GLY A  86
TRP A  87
LYS A 105
HIS A 110
ASP A 146
ILE A 147
 SAM  A 311 (-3.3A)
SAM  A 311 (-3.5A)
MLT  A 313 ( 3.0A)
SAM  A 311 (-4.1A)
SAM  A 311 (-3.8A)
SAM  A 311 ( 4.3A)
 1.48A 5njvD-5ikmA:
39.8		 5njvD-5ikmA:
62.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NZW_A_9F2A1102_1
(DNA CROSS-LINK
REPAIR 1A PROTEIN)		 3g1p PROTEIN PHNP
(Escherichia
coli) 		6 / 10 HIS A  76
HIS A  78
HIS A  81
HIS A 143
ASP A 164
HIS A 200
 MN  A 400 ( 3.4A)
MN  A 400 ( 3.3A)
MN  A 401 (-3.5A)
MN  A 400 ( 3.4A)
MN  A 401 (-2.1A)
MLT  A 500 (-4.1A)
 0.36A 5nzwA-3g1pA:
12.7		 5nzwA-3g1pA:
21.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NZW_A_9F2A1102_1
(DNA CROSS-LINK
REPAIR 1A PROTEIN)		 3g1p PROTEIN PHNP
(Escherichia
coli) 		5 / 10 HIS A 143
HIS A  76
HIS A 200
ASP A 164
HIS A 222
 MN  A 400 ( 3.4A)
MN  A 400 ( 3.4A)
MLT  A 500 (-4.1A)
MN  A 401 (-2.1A)
MN  A 401 (-3.7A)
 0.93A 5nzwA-3g1pA:
12.7		 5nzwA-3g1pA:
21.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OEX_A_CUA604_0
(THIOCYANATE
DEHYDROGENASE)		 3g1p PROTEIN PHNP
(Escherichia
coli) 		3 / 3 HIS A 143
HIS A 200
HIS A 222
 MN  A 400 ( 3.4A)
MLT  A 500 (-4.1A)
MN  A 401 (-3.7A)
 0.99A 5oexA-3g1pA:
undetectable		 5oexA-3g1pA:
19.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OGJ_A_ACTA307_0
(CARBONIC ANHYDRASE
13)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		4 / 6 HIS A 123
HIS A 125
LEU A 214
THR A 216
 ZN  A   1 ( 3.2A)
ZN  A   1 (-3.3A)
MLT  A   3 ( 4.2A)
MLT  A   3 (-2.8A)
 1.20A 5ogjA-3q31A:
24.5		 5ogjA-3q31A:
27.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OGJ_A_ACTA307_0
(CARBONIC ANHYDRASE
13)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		6 / 6 HIS A 123
HIS A 142
VAL A 154
LEU A 214
THR A 215
TRP A 225
 ZN  A   1 ( 3.2A)
ZN  A   1 ( 3.2A)
MLT  A   3 (-4.6A)
MLT  A   3 ( 4.2A)
MLT  A   3 ( 4.3A)
MLT  A   3 (-4.9A)
 0.41A 5ogjA-3q31A:
24.5		 5ogjA-3q31A:
27.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OGJ_A_ACTA307_0
(CARBONIC ANHYDRASE
13)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		4 / 6 HIS A 142
VAL A 144
LEU A 214
THR A 215
 ZN  A   1 ( 3.2A)
None
MLT  A   3 ( 4.2A)
MLT  A   3 ( 4.3A)
 1.17A 5ogjA-3q31A:
24.5		 5ogjA-3q31A:
27.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OGJ_B_ACTB305_0
(CARBONIC ANHYDRASE
13)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		4 / 6 HIS A 123
HIS A 125
LEU A 214
THR A 216
 ZN  A   1 ( 3.2A)
ZN  A   1 (-3.3A)
MLT  A   3 ( 4.2A)
MLT  A   3 (-2.8A)
 1.19A 5ogjB-3q31A:
23.7		 5ogjB-3q31A:
27.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OGJ_B_ACTB305_0
(CARBONIC ANHYDRASE
13)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		6 / 6 HIS A 123
HIS A 142
VAL A 154
LEU A 214
THR A 215
TRP A 225
 ZN  A   1 ( 3.2A)
ZN  A   1 ( 3.2A)
MLT  A   3 (-4.6A)
MLT  A   3 ( 4.2A)
MLT  A   3 ( 4.3A)
MLT  A   3 (-4.9A)
 0.38A 5ogjB-3q31A:
23.7		 5ogjB-3q31A:
27.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OGJ_B_ACTB305_0
(CARBONIC ANHYDRASE
13)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		4 / 6 HIS A 142
VAL A 144
LEU A 214
THR A 215
 ZN  A   1 ( 3.2A)
None
MLT  A   3 ( 4.2A)
MLT  A   3 ( 4.3A)
 1.16A 5ogjB-3q31A:
23.7		 5ogjB-3q31A:
27.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OHH_A_ACTA307_0
(CARBONIC ANHYDRASE
13)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		4 / 5 HIS A 123
HIS A 125
LEU A 214
THR A 216
 ZN  A   1 ( 3.2A)
ZN  A   1 (-3.3A)
MLT  A   3 ( 4.2A)
MLT  A   3 (-2.8A)
 1.19A 5ohhA-3q31A:
23.8		 5ohhA-3q31A:
27.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OHH_A_ACTA307_0
(CARBONIC ANHYDRASE
13)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		5 / 5 HIS A 123
HIS A 142
VAL A 154
LEU A 214
THR A 215
 ZN  A   1 ( 3.2A)
ZN  A   1 ( 3.2A)
MLT  A   3 (-4.6A)
MLT  A   3 ( 4.2A)
MLT  A   3 ( 4.3A)
 0.35A 5ohhA-3q31A:
23.8		 5ohhA-3q31A:
27.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OHH_A_ACTA307_0
(CARBONIC ANHYDRASE
13)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		4 / 5 HIS A 142
VAL A 144
LEU A 214
THR A 215
 ZN  A   1 ( 3.2A)
None
MLT  A   3 ( 4.2A)
MLT  A   3 ( 4.3A)
 1.16A 5ohhA-3q31A:
23.8		 5ohhA-3q31A:
27.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OHH_B_ACTB311_0
(CARBONIC ANHYDRASE
13)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		4 / 6 HIS A 123
HIS A 125
LEU A 214
THR A 216
 ZN  A   1 ( 3.2A)
ZN  A   1 (-3.3A)
MLT  A   3 ( 4.2A)
MLT  A   3 (-2.8A)
 1.19A 5ohhB-3q31A:
24.5		 5ohhB-3q31A:
27.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OHH_B_ACTB311_0
(CARBONIC ANHYDRASE
13)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		6 / 6 HIS A 123
HIS A 142
VAL A 154
LEU A 214
THR A 215
TRP A 225
 ZN  A   1 ( 3.2A)
ZN  A   1 ( 3.2A)
MLT  A   3 (-4.6A)
MLT  A   3 ( 4.2A)
MLT  A   3 ( 4.3A)
MLT  A   3 (-4.9A)
 0.39A 5ohhB-3q31A:
24.5		 5ohhB-3q31A:
27.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OHH_B_ACTB311_0
(CARBONIC ANHYDRASE
13)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		4 / 6 HIS A 142
VAL A 144
LEU A 214
THR A 215
 ZN  A   1 ( 3.2A)
None
MLT  A   3 ( 4.2A)
MLT  A   3 ( 4.3A)
 1.16A 5ohhB-3q31A:
24.5		 5ohhB-3q31A:
27.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_A_EZLA303_1
(ALPHA-CARBONIC
ANHYDRASE)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		9 / 10 HIS A 123
HIS A 125
HIS A 142
VAL A 144
VAL A 154
LEU A 214
THR A 215
PRO A 218
TRP A 225
 ZN  A   1 ( 3.2A)
ZN  A   1 (-3.3A)
ZN  A   1 ( 3.2A)
None
MLT  A   3 (-4.6A)
MLT  A   3 ( 4.2A)
MLT  A   3 ( 4.3A)
None
MLT  A   3 (-4.9A)
 0.54A 5tt3A-3q31A:
26.0		 5tt3A-3q31A:
29.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_A_EZLA303_1
(ALPHA-CARBONIC
ANHYDRASE)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		6 / 10 HIS A 123
HIS A 125
VAL A 144
LEU A 214
THR A 215
PRO A 218
 ZN  A   1 ( 3.2A)
ZN  A   1 (-3.3A)
None
MLT  A   3 ( 4.2A)
MLT  A   3 ( 4.3A)
None
 1.14A 5tt3A-3q31A:
26.0		 5tt3A-3q31A:
29.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_A_EZLA303_1
(ALPHA-CARBONIC
ANHYDRASE)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		6 / 10 HIS A 123
HIS A 142
LEU A 214
THR A 215
PRO A 217
TRP A 225
 ZN  A   1 ( 3.2A)
ZN  A   1 ( 3.2A)
MLT  A   3 ( 4.2A)
MLT  A   3 ( 4.3A)
None
MLT  A   3 (-4.9A)
 1.39A 5tt3A-3q31A:
26.0		 5tt3A-3q31A:
29.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_A_EZLA303_1
(ALPHA-CARBONIC
ANHYDRASE)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		6 / 10 HIS A 123
HIS A 142
VAL A 154
LEU A 214
PRO A 218
TRP A 225
 ZN  A   1 ( 3.2A)
ZN  A   1 ( 3.2A)
MLT  A   3 (-4.6A)
MLT  A   3 ( 4.2A)
None
MLT  A   3 (-4.9A)
 1.45A 5tt3A-3q31A:
26.0		 5tt3A-3q31A:
29.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_A_EZLA303_1
(ALPHA-CARBONIC
ANHYDRASE)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		6 / 10 HIS A 125
HIS A 123
VAL A 144
LEU A 214
THR A 215
PRO A 218
 ZN  A   1 (-3.3A)
ZN  A   1 ( 3.2A)
None
MLT  A   3 ( 4.2A)
MLT  A   3 ( 4.3A)
None
 1.44A 5tt3A-3q31A:
26.0		 5tt3A-3q31A:
29.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_B_EZLB303_1
(ALPHA-CARBONIC
ANHYDRASE)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		8 / 9 HIS A 123
HIS A 125
HIS A 142
VAL A 144
VAL A 154
LEU A 214
THR A 215
TRP A 225
 ZN  A   1 ( 3.2A)
ZN  A   1 (-3.3A)
ZN  A   1 ( 3.2A)
None
MLT  A   3 (-4.6A)
MLT  A   3 ( 4.2A)
MLT  A   3 ( 4.3A)
MLT  A   3 (-4.9A)
 0.45A 5tt3B-3q31A:
24.2		 5tt3B-3q31A:
29.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_B_EZLB303_1
(ALPHA-CARBONIC
ANHYDRASE)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		5 / 9 HIS A 123
HIS A 125
VAL A 144
LEU A 214
THR A 215
 ZN  A   1 ( 3.2A)
ZN  A   1 (-3.3A)
None
MLT  A   3 ( 4.2A)
MLT  A   3 ( 4.3A)
 1.21A 5tt3B-3q31A:
24.2		 5tt3B-3q31A:
29.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_B_EZLB303_1
(ALPHA-CARBONIC
ANHYDRASE)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		5 / 9 HIS A 125
HIS A 123
VAL A 144
LEU A 214
THR A 215
 ZN  A   1 (-3.3A)
ZN  A   1 ( 3.2A)
None
MLT  A   3 ( 4.2A)
MLT  A   3 ( 4.3A)
 1.28A 5tt3B-3q31A:
24.2		 5tt3B-3q31A:
29.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_C_EZLC303_1
(ALPHA-CARBONIC
ANHYDRASE)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		7 / 10 HIS A 123
HIS A 125
HIS A 142
VAL A 144
LEU A 214
THR A 215
PRO A 218
 ZN  A   1 ( 3.2A)
ZN  A   1 (-3.3A)
ZN  A   1 ( 3.2A)
None
MLT  A   3 ( 4.2A)
MLT  A   3 ( 4.3A)
None
 1.08A 5tt3C-3q31A:
26.2		 5tt3C-3q31A:
29.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_C_EZLC303_1
(ALPHA-CARBONIC
ANHYDRASE)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		9 / 10 HIS A 123
HIS A 125
HIS A 142
VAL A 144
VAL A 154
LEU A 214
THR A 215
PRO A 218
TRP A 225
 ZN  A   1 ( 3.2A)
ZN  A   1 (-3.3A)
ZN  A   1 ( 3.2A)
None
MLT  A   3 (-4.6A)
MLT  A   3 ( 4.2A)
MLT  A   3 ( 4.3A)
None
MLT  A   3 (-4.9A)
 0.46A 5tt3C-3q31A:
26.2		 5tt3C-3q31A:
29.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_C_EZLC303_1
(ALPHA-CARBONIC
ANHYDRASE)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		7 / 10 HIS A 123
HIS A 142
VAL A 144
LEU A 214
THR A 215
PRO A 217
TRP A 225
 ZN  A   1 ( 3.2A)
ZN  A   1 ( 3.2A)
None
MLT  A   3 ( 4.2A)
MLT  A   3 ( 4.3A)
None
MLT  A   3 (-4.9A)
 1.41A 5tt3C-3q31A:
26.2		 5tt3C-3q31A:
29.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_C_EZLC303_1
(ALPHA-CARBONIC
ANHYDRASE)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		6 / 10 HIS A 123
HIS A 142
VAL A 154
LEU A 214
PRO A 218
TRP A 225
 ZN  A   1 ( 3.2A)
ZN  A   1 ( 3.2A)
MLT  A   3 (-4.6A)
MLT  A   3 ( 4.2A)
None
MLT  A   3 (-4.9A)
 1.35A 5tt3C-3q31A:
26.2		 5tt3C-3q31A:
29.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_C_EZLC303_1
(ALPHA-CARBONIC
ANHYDRASE)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		6 / 10 HIS A 125
HIS A 123
VAL A 144
LEU A 214
THR A 215
PRO A 218
 ZN  A   1 (-3.3A)
ZN  A   1 ( 3.2A)
None
MLT  A   3 ( 4.2A)
MLT  A   3 ( 4.3A)
None
 1.45A 5tt3C-3q31A:
26.2		 5tt3C-3q31A:
29.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_E_EZLE303_1
(ALPHA-CARBONIC
ANHYDRASE)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		8 / 9 HIS A 123
HIS A 125
HIS A 142
VAL A 144
VAL A 154
LEU A 214
THR A 215
TRP A 225
 ZN  A   1 ( 3.2A)
ZN  A   1 (-3.3A)
ZN  A   1 ( 3.2A)
None
MLT  A   3 (-4.6A)
MLT  A   3 ( 4.2A)
MLT  A   3 ( 4.3A)
MLT  A   3 (-4.9A)
 0.43A 5tt3E-3q31A:
26.2		 5tt3E-3q31A:
29.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_E_EZLE303_1
(ALPHA-CARBONIC
ANHYDRASE)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		6 / 9 HIS A 123
HIS A 142
VAL A 154
LEU A 214
THR A 215
TRP A 225
 ZN  A   1 ( 3.2A)
ZN  A   1 ( 3.2A)
MLT  A   3 (-4.6A)
MLT  A   3 ( 4.2A)
MLT  A   3 ( 4.3A)
MLT  A   3 (-4.9A)
 1.49A 5tt3E-3q31A:
26.2		 5tt3E-3q31A:
29.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_E_EZLE303_1
(ALPHA-CARBONIC
ANHYDRASE)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		5 / 9 HIS A 125
HIS A 142
VAL A 144
LEU A 214
THR A 215
 ZN  A   1 (-3.3A)
ZN  A   1 ( 3.2A)
None
MLT  A   3 ( 4.2A)
MLT  A   3 ( 4.3A)
 1.08A 5tt3E-3q31A:
26.2		 5tt3E-3q31A:
29.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_F_EZLF302_1
(ALPHA-CARBONIC
ANHYDRASE)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		5 / 8 HIS A 123
HIS A 125
HIS A 142
VAL A 144
LEU A 214
 ZN  A   1 ( 3.2A)
ZN  A   1 (-3.3A)
ZN  A   1 ( 3.2A)
None
MLT  A   3 ( 4.2A)
 1.12A 5tt3F-3q31A:
25.5		 5tt3F-3q31A:
29.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_F_EZLF302_1
(ALPHA-CARBONIC
ANHYDRASE)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		8 / 8 HIS A 123
HIS A 125
HIS A 142
VAL A 144
VAL A 154
LEU A 214
THR A 215
TRP A 225
 ZN  A   1 ( 3.2A)
ZN  A   1 (-3.3A)
ZN  A   1 ( 3.2A)
None
MLT  A   3 (-4.6A)
MLT  A   3 ( 4.2A)
MLT  A   3 ( 4.3A)
MLT  A   3 (-4.9A)
 0.54A 5tt3F-3q31A:
25.5		 5tt3F-3q31A:
29.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_F_EZLF302_1
(ALPHA-CARBONIC
ANHYDRASE)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		5 / 8 HIS A 123
HIS A 142
VAL A 154
LEU A 214
TRP A 225
 ZN  A   1 ( 3.2A)
ZN  A   1 ( 3.2A)
MLT  A   3 (-4.6A)
MLT  A   3 ( 4.2A)
MLT  A   3 (-4.9A)
 1.39A 5tt3F-3q31A:
25.5		 5tt3F-3q31A:
29.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_G_EZLG303_1
(ALPHA-CARBONIC
ANHYDRASE)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		8 / 9 HIS A 123
HIS A 125
HIS A 142
VAL A 144
VAL A 154
LEU A 214
THR A 215
TRP A 225
 ZN  A   1 ( 3.2A)
ZN  A   1 (-3.3A)
ZN  A   1 ( 3.2A)
None
MLT  A   3 (-4.6A)
MLT  A   3 ( 4.2A)
MLT  A   3 ( 4.3A)
MLT  A   3 (-4.9A)
 0.42A 5tt3G-3q31A:
25.7		 5tt3G-3q31A:
29.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_G_EZLG303_1
(ALPHA-CARBONIC
ANHYDRASE)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		6 / 9 HIS A 123
HIS A 142
VAL A 154
LEU A 214
THR A 215
TRP A 225
 ZN  A   1 ( 3.2A)
ZN  A   1 ( 3.2A)
MLT  A   3 (-4.6A)
MLT  A   3 ( 4.2A)
MLT  A   3 ( 4.3A)
MLT  A   3 (-4.9A)
 1.50A 5tt3G-3q31A:
25.7		 5tt3G-3q31A:
29.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_G_EZLG303_1
(ALPHA-CARBONIC
ANHYDRASE)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		5 / 9 HIS A 125
HIS A 123
VAL A 144
LEU A 214
THR A 215
 ZN  A   1 (-3.3A)
ZN  A   1 ( 3.2A)
None
MLT  A   3 ( 4.2A)
MLT  A   3 ( 4.3A)
 1.36A 5tt3G-3q31A:
25.7		 5tt3G-3q31A:
29.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_G_EZLG303_1
(ALPHA-CARBONIC
ANHYDRASE)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		5 / 9 HIS A 125
HIS A 142
VAL A 144
LEU A 214
THR A 215
 ZN  A   1 (-3.3A)
ZN  A   1 ( 3.2A)
None
MLT  A   3 ( 4.2A)
MLT  A   3 ( 4.3A)
 1.09A 5tt3G-3q31A:
25.7		 5tt3G-3q31A:
29.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_H_EZLH303_1
(ALPHA-CARBONIC
ANHYDRASE)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		7 / 8 HIS A 123
HIS A 125
HIS A 142
VAL A 144
LEU A 214
THR A 215
TRP A 225
 ZN  A   1 ( 3.2A)
ZN  A   1 (-3.3A)
ZN  A   1 ( 3.2A)
None
MLT  A   3 ( 4.2A)
MLT  A   3 ( 4.3A)
MLT  A   3 (-4.9A)
 0.49A 5tt3H-3q31A:
25.6		 5tt3H-3q31A:
29.17
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5VIM_A_SAMA301_0
(METHYLTRANSFERASE)		 5ikm NS5 METHYL
TRANSFERASE
(Dengue
virus) 		11 / 12 GLY A  58
GLY A  81
GLY A  83
GLY A  86
TRP A  87
LYS A 105
HIS A 110
VAL A 132
PHE A 133
ILE A 147
LYS A 180
 SAM  A 311 (-3.3A)
SAM  A 311 (-3.2A)
SAM  A 311 (-3.3A)
SAM  A 311 (-3.3A)
SAM  A 311 (-3.5A)
MLT  A 313 ( 3.0A)
SAM  A 311 (-4.1A)
SAM  A 311 (-3.7A)
SAM  A 311 ( 4.4A)
SAM  A 311 ( 4.3A)
None
 0.48A 5vimA-5ikmA:
41.0		 5vimA-5ikmA:
62.31
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5VIM_A_SAMA301_0
(METHYLTRANSFERASE)		 5ikm NS5 METHYL
TRANSFERASE
(Dengue
virus) 		6 / 12 GLY A  86
TRP A  87
LYS A 105
HIS A 110
PHE A 133
ILE A 147
 SAM  A 311 (-3.3A)
SAM  A 311 (-3.5A)
MLT  A 313 ( 3.0A)
SAM  A 311 (-4.1A)
SAM  A 311 ( 4.4A)
SAM  A 311 ( 4.3A)
 1.45A 5vimA-5ikmA:
41.0		 5vimA-5ikmA:
62.31
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5VIM_A_SAMA301_1
(METHYLTRANSFERASE)		 5ikm NS5 METHYL
TRANSFERASE
(Dengue
virus) 		4 / 4 SER A  56
THR A 104
ASP A 131
ASP A 146
 SAM  A 311 ( 2.7A)
SAM  A 311 (-4.5A)
MLT  A 313 ( 2.6A)
SAM  A 311 (-3.8A)
 0.31A 5vimA-5ikmA:
41.0		 5vimA-5ikmA:
62.31
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5VIM_B_SAMB301_0
(METHYLTRANSFERASE)		 5ikm NS5 METHYL
TRANSFERASE
(Dengue
virus) 		11 / 12 GLY A  58
GLY A  81
GLY A  83
GLY A  86
TRP A  87
LYS A 105
HIS A 110
VAL A 132
PHE A 133
ILE A 147
LYS A 180
 SAM  A 311 (-3.3A)
SAM  A 311 (-3.2A)
SAM  A 311 (-3.3A)
SAM  A 311 (-3.3A)
SAM  A 311 (-3.5A)
MLT  A 313 ( 3.0A)
SAM  A 311 (-4.1A)
SAM  A 311 (-3.7A)
SAM  A 311 ( 4.4A)
SAM  A 311 ( 4.3A)
None
 0.40A 5vimB-5ikmA:
41.1		 5vimB-5ikmA:
62.31
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5VIM_B_SAMB301_0
(METHYLTRANSFERASE)		 5ikm NS5 METHYL
TRANSFERASE
(Dengue
virus) 		6 / 12 GLY A  86
TRP A  87
LYS A 105
HIS A 110
PHE A 133
ILE A 147
 SAM  A 311 (-3.3A)
SAM  A 311 (-3.5A)
MLT  A 313 ( 3.0A)
SAM  A 311 (-4.1A)
SAM  A 311 ( 4.4A)
SAM  A 311 ( 4.3A)
 1.44A 5vimB-5ikmA:
41.1		 5vimB-5ikmA:
62.31
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5VIM_B_SAMB301_1
(METHYLTRANSFERASE)		 5ikm NS5 METHYL
TRANSFERASE
(Dengue
virus) 		4 / 4 SER A  56
THR A 104
ASP A 131
ASP A 146
 SAM  A 311 ( 2.7A)
SAM  A 311 (-4.5A)
MLT  A 313 ( 2.6A)
SAM  A 311 (-3.8A)
 0.20A 5vimB-5ikmA:
41.1		 5vimB-5ikmA:
62.31
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5WZ1_A_SAMA601_0
(NS5
METHYLTRANSFERASE)		 5ikm NS5 METHYL
TRANSFERASE
(Dengue
virus) 		12 / 12 GLY A  58
GLY A  81
GLY A  86
TRP A  87
THR A 104
LYS A 105
HIS A 110
GLU A 111
ASP A 131
VAL A 132
ASP A 146
ILE A 147
 SAM  A 311 (-3.3A)
SAM  A 311 (-3.2A)
SAM  A 311 (-3.3A)
SAM  A 311 (-3.5A)
SAM  A 311 (-4.5A)
MLT  A 313 ( 3.0A)
SAM  A 311 (-4.1A)
None
MLT  A 313 ( 2.6A)
SAM  A 311 (-3.7A)
SAM  A 311 (-3.8A)
SAM  A 311 ( 4.3A)
 0.71A 5wz1A-5ikmA:
41.0		 5wz1A-5ikmA:
60.73
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5WZ1_B_SAMB601_0
(NS5
METHYLTRANSFERASE)		 5ikm NS5 METHYL
TRANSFERASE
(Dengue
virus) 		12 / 12 GLY A  58
GLY A  81
GLY A  83
GLY A  86
TRP A  87
THR A 104
LYS A 105
HIS A 110
GLU A 111
ASP A 131
VAL A 132
ILE A 147
 SAM  A 311 (-3.3A)
SAM  A 311 (-3.2A)
SAM  A 311 (-3.3A)
SAM  A 311 (-3.3A)
SAM  A 311 (-3.5A)
SAM  A 311 (-4.5A)
MLT  A 313 ( 3.0A)
SAM  A 311 (-4.1A)
None
MLT  A 313 ( 2.6A)
SAM  A 311 (-3.7A)
SAM  A 311 ( 4.3A)
 0.70A 5wz1B-5ikmA:
40.9		 5wz1B-5ikmA:
60.73
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5WZ1_C_SAMC601_0
(NS5
METHYLTRANSFERASE)		 5ikm NS5 METHYL
TRANSFERASE
(Dengue
virus) 		11 / 12 GLY A  58
GLY A  81
GLY A  86
TRP A  87
THR A 104
LYS A 105
HIS A 110
ASP A 131
VAL A 132
ASP A 146
ILE A 147
 SAM  A 311 (-3.3A)
SAM  A 311 (-3.2A)
SAM  A 311 (-3.3A)
SAM  A 311 (-3.5A)
SAM  A 311 (-4.5A)
MLT  A 313 ( 3.0A)
SAM  A 311 (-4.1A)
MLT  A 313 ( 2.6A)
SAM  A 311 (-3.7A)
SAM  A 311 (-3.8A)
SAM  A 311 ( 4.3A)
 0.57A 5wz1C-5ikmA:
40.9		 5wz1C-5ikmA:
60.73
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5WZ1_C_SAMC601_0
(NS5
METHYLTRANSFERASE)		 5ikm NS5 METHYL
TRANSFERASE
(Dengue
virus) 		11 / 12 GLY A  81
GLY A  86
TRP A  87
THR A 104
LYS A 105
HIS A 110
GLU A 111
ASP A 131
VAL A 132
ASP A 146
ILE A 147
 SAM  A 311 (-3.2A)
SAM  A 311 (-3.3A)
SAM  A 311 (-3.5A)
SAM  A 311 (-4.5A)
MLT  A 313 ( 3.0A)
SAM  A 311 (-4.1A)
None
MLT  A 313 ( 2.6A)
SAM  A 311 (-3.7A)
SAM  A 311 (-3.8A)
SAM  A 311 ( 4.3A)
 0.75A 5wz1C-5ikmA:
40.9		 5wz1C-5ikmA:
60.73
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5WZ1_D_SAMD601_0
(NS5
METHYLTRANSFERASE)		 5ikm NS5 METHYL
TRANSFERASE
(Dengue
virus) 		12 / 12 GLY A  58
GLY A  81
GLY A  86
TRP A  87
THR A 104
LYS A 105
HIS A 110
GLU A 111
ASP A 131
VAL A 132
ASP A 146
ILE A 147
 SAM  A 311 (-3.3A)
SAM  A 311 (-3.2A)
SAM  A 311 (-3.3A)
SAM  A 311 (-3.5A)
SAM  A 311 (-4.5A)
MLT  A 313 ( 3.0A)
SAM  A 311 (-4.1A)
None
MLT  A 313 ( 2.6A)
SAM  A 311 (-3.7A)
SAM  A 311 (-3.8A)
SAM  A 311 ( 4.3A)
 0.73A 5wz1D-5ikmA:
40.9		 5wz1D-5ikmA:
60.73
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5WZ1_E_SAME601_0
(NS5
METHYLTRANSFERASE)		 5ikm NS5 METHYL
TRANSFERASE
(Dengue
virus) 		11 / 12 GLY A  58
GLY A  81
GLY A  86
TRP A  87
THR A 104
LYS A 105
HIS A 110
ASP A 131
VAL A 132
ASP A 146
ILE A 147
 SAM  A 311 (-3.3A)
SAM  A 311 (-3.2A)
SAM  A 311 (-3.3A)
SAM  A 311 (-3.5A)
SAM  A 311 (-4.5A)
MLT  A 313 ( 3.0A)
SAM  A 311 (-4.1A)
MLT  A 313 ( 2.6A)
SAM  A 311 (-3.7A)
SAM  A 311 (-3.8A)
SAM  A 311 ( 4.3A)
 0.57A 5wz1E-5ikmA:
40.9		 5wz1E-5ikmA:
60.73
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5WZ1_E_SAME601_0
(NS5
METHYLTRANSFERASE)		 5ikm NS5 METHYL
TRANSFERASE
(Dengue
virus) 		11 / 12 GLY A  81
GLY A  86
TRP A  87
THR A 104
LYS A 105
HIS A 110
GLU A 111
ASP A 131
VAL A 132
ASP A 146
ILE A 147
 SAM  A 311 (-3.2A)
SAM  A 311 (-3.3A)
SAM  A 311 (-3.5A)
SAM  A 311 (-4.5A)
MLT  A 313 ( 3.0A)
SAM  A 311 (-4.1A)
None
MLT  A 313 ( 2.6A)
SAM  A 311 (-3.7A)
SAM  A 311 (-3.8A)
SAM  A 311 ( 4.3A)
 0.75A 5wz1E-5ikmA:
40.9		 5wz1E-5ikmA:
60.73
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5WZ1_F_SAMF601_0
(NS5
METHYLTRANSFERASE)		 5ikm NS5 METHYL
TRANSFERASE
(Dengue
virus) 		11 / 12 GLY A  58
GLY A  81
GLY A  86
TRP A  87
THR A 104
LYS A 105
HIS A 110
ASP A 131
VAL A 132
ASP A 146
ILE A 147
 SAM  A 311 (-3.3A)
SAM  A 311 (-3.2A)
SAM  A 311 (-3.3A)
SAM  A 311 (-3.5A)
SAM  A 311 (-4.5A)
MLT  A 313 ( 3.0A)
SAM  A 311 (-4.1A)
MLT  A 313 ( 2.6A)
SAM  A 311 (-3.7A)
SAM  A 311 (-3.8A)
SAM  A 311 ( 4.3A)
 0.57A 5wz1F-5ikmA:
40.9		 5wz1F-5ikmA:
60.73
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5WZ1_F_SAMF601_0
(NS5
METHYLTRANSFERASE)		 5ikm NS5 METHYL
TRANSFERASE
(Dengue
virus) 		11 / 12 GLY A  81
GLY A  86
TRP A  87
THR A 104
LYS A 105
HIS A 110
GLU A 111
ASP A 131
VAL A 132
ASP A 146
ILE A 147
 SAM  A 311 (-3.2A)
SAM  A 311 (-3.3A)
SAM  A 311 (-3.5A)
SAM  A 311 (-4.5A)
MLT  A 313 ( 3.0A)
SAM  A 311 (-4.1A)
None
MLT  A 313 ( 2.6A)
SAM  A 311 (-3.7A)
SAM  A 311 (-3.8A)
SAM  A 311 ( 4.3A)
 0.75A 5wz1F-5ikmA:
40.9		 5wz1F-5ikmA:
60.73
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5WZ1_G_SAMG601_0
(NS5
METHYLTRANSFERASE)		 5ikm NS5 METHYL
TRANSFERASE
(Dengue
virus) 		12 / 12 GLY A  58
GLY A  81
GLY A  86
TRP A  87
THR A 104
LYS A 105
HIS A 110
GLU A 111
ASP A 131
VAL A 132
ASP A 146
ILE A 147
 SAM  A 311 (-3.3A)
SAM  A 311 (-3.2A)
SAM  A 311 (-3.3A)
SAM  A 311 (-3.5A)
SAM  A 311 (-4.5A)
MLT  A 313 ( 3.0A)
SAM  A 311 (-4.1A)
None
MLT  A 313 ( 2.6A)
SAM  A 311 (-3.7A)
SAM  A 311 (-3.8A)
SAM  A 311 ( 4.3A)
 0.72A 5wz1G-5ikmA:
40.8		 5wz1G-5ikmA:
60.73
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5WZ1_H_SAMH601_0
(NS5
METHYLTRANSFERASE)		 5ikm NS5 METHYL
TRANSFERASE
(Dengue
virus) 		11 / 12 GLY A  58
GLY A  81
GLY A  86
TRP A  87
THR A 104
LYS A 105
HIS A 110
ASP A 131
VAL A 132
ASP A 146
ILE A 147
 SAM  A 311 (-3.3A)
SAM  A 311 (-3.2A)
SAM  A 311 (-3.3A)
SAM  A 311 (-3.5A)
SAM  A 311 (-4.5A)
MLT  A 313 ( 3.0A)
SAM  A 311 (-4.1A)
MLT  A 313 ( 2.6A)
SAM  A 311 (-3.7A)
SAM  A 311 (-3.8A)
SAM  A 311 ( 4.3A)
 0.58A 5wz1H-5ikmA:
40.7		 5wz1H-5ikmA:
60.73
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5WZ1_H_SAMH601_0
(NS5
METHYLTRANSFERASE)		 5ikm NS5 METHYL
TRANSFERASE
(Dengue
virus) 		11 / 12 GLY A  81
GLY A  86
TRP A  87
THR A 104
LYS A 105
HIS A 110
GLU A 111
ASP A 131
VAL A 132
ASP A 146
ILE A 147
 SAM  A 311 (-3.2A)
SAM  A 311 (-3.3A)
SAM  A 311 (-3.5A)
SAM  A 311 (-4.5A)
MLT  A 313 ( 3.0A)
SAM  A 311 (-4.1A)
None
MLT  A 313 ( 2.6A)
SAM  A 311 (-3.7A)
SAM  A 311 (-3.8A)
SAM  A 311 ( 4.3A)
 0.76A 5wz1H-5ikmA:
40.7		 5wz1H-5ikmA:
60.73
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5WZ2_A_SAMA601_0
(NS5 MTASE)		 5ikm NS5 METHYL
TRANSFERASE
(Dengue
virus) 		12 / 12 GLY A  58
GLY A  81
GLY A  83
GLY A  86
TRP A  87
THR A 104
LYS A 105
HIS A 110
ASP A 131
VAL A 132
ASP A 146
ILE A 147
 SAM  A 311 (-3.3A)
SAM  A 311 (-3.2A)
SAM  A 311 (-3.3A)
SAM  A 311 (-3.3A)
SAM  A 311 (-3.5A)
SAM  A 311 (-4.5A)
MLT  A 313 ( 3.0A)
SAM  A 311 (-4.1A)
MLT  A 313 ( 2.6A)
SAM  A 311 (-3.7A)
SAM  A 311 (-3.8A)
SAM  A 311 ( 4.3A)
 0.45A 5wz2A-5ikmA:
41.1		 5wz2A-5ikmA:
60.73
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5WZ2_B_SAMB601_0
(NS5 MTASE)		 5ikm NS5 METHYL
TRANSFERASE
(Dengue
virus) 		12 / 12 GLY A  58
GLY A  81
GLY A  83
GLY A  86
TRP A  87
THR A 104
LYS A 105
HIS A 110
ASP A 131
VAL A 132
ASP A 146
ILE A 147
 SAM  A 311 (-3.3A)
SAM  A 311 (-3.2A)
SAM  A 311 (-3.3A)
SAM  A 311 (-3.3A)
SAM  A 311 (-3.5A)
SAM  A 311 (-4.5A)
MLT  A 313 ( 3.0A)
SAM  A 311 (-4.1A)
MLT  A 313 ( 2.6A)
SAM  A 311 (-3.7A)
SAM  A 311 (-3.8A)
SAM  A 311 ( 4.3A)
 0.63A 5wz2B-5ikmA:
41.4		 5wz2B-5ikmA:
60.73
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5WZ2_C_SAMC601_0
(NS5 MTASE)		 5ikm NS5 METHYL
TRANSFERASE
(Dengue
virus) 		11 / 12 GLY A  58
GLY A  81
GLY A  83
GLY A  86
TRP A  87
THR A 104
LYS A 105
HIS A 110
GLU A 111
VAL A 132
ASP A 146
 SAM  A 311 (-3.3A)
SAM  A 311 (-3.2A)
SAM  A 311 (-3.3A)
SAM  A 311 (-3.3A)
SAM  A 311 (-3.5A)
SAM  A 311 (-4.5A)
MLT  A 313 ( 3.0A)
SAM  A 311 (-4.1A)
None
SAM  A 311 (-3.7A)
SAM  A 311 (-3.8A)
 0.89A 5wz2C-5ikmA:
41.0		 5wz2C-5ikmA:
60.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XIP_A_HFGA1003_1
(PROLYL-TRNA
SYNTHETASE, PUTATIVE)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		3 / 3 GLU A 129
TRP A 225
HIS A 123
 ZN  A   1 ( 4.7A)
MLT  A   3 (-4.9A)
ZN  A   1 ( 3.2A)
 1.08A 5xipA-3q31A:
undetectable		 5xipA-3q31A:
18.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XIP_A_HFGA1003_1
(PROLYL-TRNA
SYNTHETASE, PUTATIVE)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		3 / 3 GLU A 140
TRP A 225
HIS A 123
 None
MLT  A   3 (-4.9A)
ZN  A   1 ( 3.2A)
 1.02A 5xipA-3q31A:
undetectable		 5xipA-3q31A:
18.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZJ8_A_9DCA303_0
(METALLO-BETA-LACTAMA
SE TYPE 2)		 3g1p PROTEIN PHNP
(Escherichia
coli) 		4 / 8 HIS A  78
ASP A  80
HIS A 143
HIS A 222
 MN  A 400 ( 3.3A)
MLT  A 500 ( 2.8A)
MN  A 400 ( 3.4A)
MN  A 401 (-3.7A)
 0.91A 5zj8A-3g1pA:
9.7		 5zj8A-3g1pA:
19.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AWO_A_SREA701_1
(SODIUM-DEPENDENT
SEROTONIN
TRANSPORTER)		 4nml RIBULOSE 5-PHOSPHATE
ISOMERASE
(Toxoplasma
gondii) 		5 / 9 ASP A  91
ALA A 239
GLY A 233
PHE A 235
GLY A  99
 MLT  A 303 (-4.5A)
None
None
None
None
 1.15A 6awoA-4nmlA:
undetectable		 6awoA-4nmlA:
20.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AWQ_A_SREA701_1
(SODIUM-DEPENDENT
SEROTONIN
TRANSPORTER)		 4nml RIBULOSE 5-PHOSPHATE
ISOMERASE
(Toxoplasma
gondii) 		5 / 9 ASP A  91
ALA A 239
GLY A 233
PHE A 235
GLY A  99
 MLT  A 303 (-4.5A)
None
None
None
None
 1.16A 6awqA-4nmlA:
undetectable		 6awqA-4nmlA:
20.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BBS_A_BZ1A302_1
(CARBONIC ANHYDRASE 2)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		7 / 12 GLN A 121
HIS A 123
HIS A 125
LEU A 214
THR A 215
THR A 216
TRP A 225
 MLT  A   3 (-3.9A)
ZN  A   1 ( 3.2A)
ZN  A   1 (-3.3A)
MLT  A   3 ( 4.2A)
MLT  A   3 ( 4.3A)
MLT  A   3 (-2.8A)
MLT  A   3 (-4.9A)
 0.48A 6bbsA-3q31A:
20.1		 6bbsA-3q31A:
15.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BBS_A_BZ1A302_1
(CARBONIC ANHYDRASE 2)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		6 / 12 TRP A  48
GLN A 121
HIS A 123
HIS A 125
LEU A 214
THR A 216
 None
MLT  A   3 (-3.9A)
ZN  A   1 ( 3.2A)
ZN  A   1 (-3.3A)
MLT  A   3 ( 4.2A)
MLT  A   3 (-2.8A)
 1.39A 6bbsA-3q31A:
20.1		 6bbsA-3q31A:
15.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BC9_A_ETSA302_1
(CARBONIC ANHYDRASE 2)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		9 / 12 GLN A 121
HIS A 123
HIS A 125
VAL A 144
LEU A 214
THR A 215
THR A 216
PRO A 218
TRP A 225
 MLT  A   3 (-3.9A)
ZN  A   1 ( 3.2A)
ZN  A   1 (-3.3A)
None
MLT  A   3 ( 4.2A)
MLT  A   3 ( 4.3A)
MLT  A   3 (-2.8A)
None
MLT  A   3 (-4.9A)
 0.51A 6bc9A-3q31A:
24.3		 6bc9A-3q31A:
15.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BC9_A_ETSA302_1
(CARBONIC ANHYDRASE 2)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		7 / 12 TRP A  48
HIS A 123
HIS A 125
VAL A 144
LEU A 214
THR A 216
TRP A 225
 None
ZN  A   1 ( 3.2A)
ZN  A   1 (-3.3A)
None
MLT  A   3 ( 4.2A)
MLT  A   3 (-2.8A)
MLT  A   3 (-4.9A)
 1.34A 6bc9A-3q31A:
24.3		 6bc9A-3q31A:
15.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BCC_A_EZLA302_1
(CARBONIC ANHYDRASE 2)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		10 / 12 GLN A 121
HIS A 123
HIS A 125
VAL A 144
VAL A 154
LEU A 214
THR A 215
THR A 216
PRO A 218
TRP A 225
 MLT  A   3 (-3.9A)
ZN  A   1 ( 3.2A)
ZN  A   1 (-3.3A)
None
MLT  A   3 (-4.6A)
MLT  A   3 ( 4.2A)
MLT  A   3 ( 4.3A)
MLT  A   3 (-2.8A)
None
MLT  A   3 (-4.9A)
 0.45A 6bccA-3q31A:
24.4		 6bccA-3q31A:
15.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BCC_A_EZLA302_1
(CARBONIC ANHYDRASE 2)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		7 / 12 GLN A 121
HIS A 123
VAL A 144
LEU A 214
THR A 215
PRO A 217
TRP A 225
 MLT  A   3 (-3.9A)
ZN  A   1 ( 3.2A)
None
MLT  A   3 ( 4.2A)
MLT  A   3 ( 4.3A)
None
MLT  A   3 (-4.9A)
 1.34A 6bccA-3q31A:
24.4		 6bccA-3q31A:
15.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BCC_A_EZLA302_1
(CARBONIC ANHYDRASE 2)		 3q31 CARBONIC ANHYDRASE
(Aspergillus
oryzae) 		6 / 12 HIS A 123
VAL A 154
LEU A 214
THR A 216
PRO A 218
TRP A 225
 ZN  A   1 ( 3.2A)
MLT  A   3 (-4.6A)
MLT  A   3 ( 4.2A)
MLT  A   3 (-2.8A)
None
MLT  A   3 (-4.9A)
 1.29A 6bccA-3q31A:
24.4		 6bccA-3q31A:
15.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BTX_A_EDTA503_0
(SOLUTE CARRIER
FAMILY 39
(IRON-REGULATED
TRANSPORTER))		 4a29 ENGINEERED
RETRO-ALDOL ENZYME
RA95.0
(synthetic
construct) 		4 / 7 SER A  56
SER A 234
GLY A 212
ARG A 238
 MLT  A 300 (-3.8A)
MLT  A 300 (-3.0A)
MLT  A 300 (-2.8A)
None
 1.15A 6btxA-4a29A:
undetectable		 6btxA-4a29A:
21.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6G1P_B_ACTB403_0
(ADP-RIBOSYLHYDROLASE
LIKE 2)		 3uk2 PANTOTHENATE
SYNTHETASE
(Burkholderia
thailandensis) 		3 / 3 PHE A  58
ARG A 118
GLN A  57
 None
MLT  A 284 (-3.3A)
EDO  A 285 ( 3.0A)
 1.17A 6g1pB-3uk2A:
undetectable		 6g1pB-3uk2A:
24.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GNA_A_ACTA307_0
(THIOREDOXIN
REDUCTASE)		 5a2r ANGIOTENSIN-CONVERTI
NG ENZYME
(Drosophila
melanogaster) 		3 / 3 ARG A 473
LYS A 495
TYR A 170
 None
MLT  A1615 (-2.7A)
None
 1.17A 6gnaA-5a2rA:
undetectable		 6gnaA-5a2rA:
18.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GNB_A_ACTA307_0
(THIOREDOXIN
REDUCTASE)		 5a2r ANGIOTENSIN-CONVERTI
NG ENZYME
(Drosophila
melanogaster) 		3 / 3 ARG A 473
LYS A 495
TYR A 170
 None
MLT  A1615 (-2.7A)
None
 1.17A 6gnbA-5a2rA:
undetectable		 6gnbA-5a2rA:
18.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NJ9_K_SAMK500_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE,
H3 LYSINE-79
SPECIFIC)		 5ikm NS5 METHYL
TRANSFERASE
(Dengue
virus) 		5 / 12 ASP A  79
GLY A  81
GLY A  83
LYS A 105
ASP A 131
 SAM  A 311 ( 4.9A)
SAM  A 311 (-3.2A)
SAM  A 311 (-3.3A)
MLT  A 313 ( 3.0A)
MLT  A 313 ( 2.6A)
 0.54A 6nj9K-5ikmA:
7.5		 6nj9K-5ikmA:
22.54