SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '154l'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SGU_B_MK1B2632_1
(POL POLYPROTEIN)		 154l GOOSE LYSOZYME
(Anser
anser) 		5 / 8 ASP A 161
ALA A 170
ILE A  11
ILE A 127
ALA A 158
 None
 1.30A 1sguA-154lA:
undetectable		 1sguA-154lA:
21.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F9W_A_PAUA6002_0
(PANTOTHENATE KINASE)		 154l GOOSE LYSOZYME
(Anser
anser) 		4 / 8 ARG A 155
GLY A 152
THR A 126
ILE A 127
 None
 0.91A 2f9wA-154lA:
undetectable
2f9wB-154lA:
undetectable		 2f9wA-154lA:
22.39
2f9wB-154lA:
22.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EWU_A_BEZA1401_0
(MAGNESIUM-CHELATASE
SUBUNIT CHLH,
CHLOROPLASTIC)		 154l GOOSE LYSOZYME
(Anser
anser) 		4 / 6 GLY A  15
THR A  13
SER A  34
VAL A  31
 None
 0.86A 5ewuA-154lA:
undetectable		 5ewuA-154lA:
17.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EWU_B_BEZB1401_0
(MAGNESIUM-CHELATASE
SUBUNIT CHLH,
CHLOROPLASTIC)		 154l GOOSE LYSOZYME
(Anser
anser) 		4 / 6 GLY A  15
THR A  13
SER A  34
VAL A  31
 None
 1.13A 5ewuB-154lA:
undetectable		 5ewuB-154lA:
17.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5W7P_A_SAMA501_0
(OXAC)		 154l GOOSE LYSOZYME
(Anser
anser) 		5 / 12 ALA A  67
GLY A  68
SER A  71
LEU A  93
ASP A  46
 None
 1.10A 5w7pA-154lA:
0.0		 5w7pA-154lA:
17.65