SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '16vp'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MCN_P_DHIP1_0
(IMMUNOGLOBULIN
LAMBDA DIMER MCG
(LIGHT CHAIN)
PEPTIDE
N-ACETYL-D-HIS-L-PRO
-NH2)		 16vp PROTEIN (VP16,
VMW65, ATIF)
(Human
alphaherpesvirus
1) 		3 / 3 PHE A 270
TYR A 149
PRO A 272
 None
 0.74A 1mcnA-16vpA:
undetectable
1mcnB-16vpA:
undetectable
1mcnP-16vpA:
undetectable		 1mcnA-16vpA:
22.16
1mcnB-16vpA:
22.16
1mcnP-16vpA:
2.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CDQ_B_SAMB1500_0
(ASPARTOKINASE)		 16vp PROTEIN (VP16,
VMW65, ATIF)
(Human
alphaherpesvirus
1) 		4 / 7 SER A 177
SER A 186
ARG A 214
GLU A 218
 None
 1.01A 2cdqB-16vpA:
undetectable		 2cdqB-16vpA:
22.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_C_SVRC507_1
(PHOSPHOLIPASE A2)		 16vp PROTEIN (VP16,
VMW65, ATIF)
(Human
alphaherpesvirus
1) 		4 / 7 VAL A 112
VAL A 113
GLY A 116
ARG A 208
 None
 0.85A 3bjwC-16vpA:
0.0		 3bjwC-16vpA:
15.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_G_SVRG506_1
(PHOSPHOLIPASE A2)		 16vp PROTEIN (VP16,
VMW65, ATIF)
(Human
alphaherpesvirus
1) 		4 / 8 VAL A 112
VAL A 113
GLY A 116
ARG A 208
 None
 0.82A 3bjwA-16vpA:
undetectable		 3bjwA-16vpA:
15.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DGQ_A_EAAA211_1
(GLUTATHIONE
S-TRANSFERASE P)		 16vp PROTEIN (VP16,
VMW65, ATIF)
(Human
alphaherpesvirus
1) 		4 / 5 ARG A 129
ILE A 128
TYR A 168
THR A 170
 None
 1.25A 3dgqA-16vpA:
0.0		 3dgqA-16vpA:
20.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PGY_A_GLYA510_0
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 16vp PROTEIN (VP16,
VMW65, ATIF)
(Human
alphaherpesvirus
1) 		4 / 6 ILE A 298
GLU A  86
PHE A  89
ALA A 332
 None
 1.08A 3pgyA-16vpA:
undetectable
3pgyB-16vpA:
undetectable		 3pgyA-16vpA:
21.60
3pgyB-16vpA:
21.60