SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1914'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

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	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1J8U_A_H4BA429_1 (PHENYLALANINE-4-HYDR OXYLASE)	1914	SIGNAL RECOGNITION PARTICLE 9/14 FUSION PROTEIN (Mus musculus)	4 / 7	LEU A2004 SER A2006 PHE A2009 LEU A2010	None	0.41A	1j8uA-1914A: undetectable	1j8uA-1914A: 20.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1KW0_A_H4BA429_1 (PHENYLALANINE-4-HYDR OXYLASE)	1914	SIGNAL RECOGNITION PARTICLE 9/14 FUSION PROTEIN (Mus musculus)	5 / 12	VAL A2002 LEU A2004 SER A2006 PHE A2009 LEU A2010	None	0.98A	1kw0A-1914A: undetectable	1kw0A-1914A: 20.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1MMK_A_H4BA1427_1 (PHENYLALANINE-4-HYDR OXYLASE)	1914	SIGNAL RECOGNITION PARTICLE 9/14 FUSION PROTEIN (Mus musculus)	5 / 12	VAL A2002 LEU A2004 SER A2006 PHE A2009 LEU A2010	None	0.92A	1mmkA-1914A: undetectable	1mmkA-1914A: 20.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1MMT_A_H4BA1426_1 (PHENYLALANINE-4-HYDR OXYLASE)	1914	SIGNAL RECOGNITION PARTICLE 9/14 FUSION PROTEIN (Mus musculus)	5 / 11	VAL A2002 LEU A2004 SER A2006 PHE A2009 LEU A2010	None	0.91A	1mmtA-1914A: undetectable	1mmtA-1914A: 20.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1V54_C_CHDC3271_0 (CYTOCHROME C OXIDASE POLYPEPTIDE III CYTOCHROME C OXIDASE POLYPEPTIDE VIIA-HEART)	1914	SIGNAL RECOGNITION PARTICLE 9/14 FUSION PROTEIN (Mus musculus)	4 / 8	LEU A2086 PHE A2017 LEU A2013 PHE A2009	None	0.84A	1v54C-1914A: 0.8 1v54J-1914A: undetectable	1v54C-1914A: 19.40 1v54J-1914A: 12.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2DYR_C_CHDC271_0 (CYTOCHROME C OXIDASE POLYPEPTIDE VIIA-HEART CYTOCHROME C OXIDASE SUBUNIT 3)	1914	SIGNAL RECOGNITION PARTICLE 9/14 FUSION PROTEIN (Mus musculus)	4 / 8	LEU A2086 PHE A2017 LEU A2013 PHE A2009	None	0.84A	2dyrC-1914A: 0.7 2dyrJ-1914A: undetectable	2dyrC-1914A: 19.40 2dyrJ-1914A: 12.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2DYR_P_CHDP1271_0 (CYTOCHROME C OXIDASE POLYPEPTIDE VIIA-HEART CYTOCHROME C OXIDASE SUBUNIT 3)	1914	SIGNAL RECOGNITION PARTICLE 9/14 FUSION PROTEIN (Mus musculus)	4 / 8	LEU A2086 PHE A2017 LEU A2013 PHE A2009	None	0.86A	2dyrP-1914A: 0.8 2dyrW-1914A: undetectable	2dyrP-1914A: 19.40 2dyrW-1914A: 12.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2EIK_C_CHDC271_0 (CYTOCHROME C OXIDASE POLYPEPTIDE VIIA-HEART CYTOCHROME C OXIDASE SUBUNIT 3)	1914	SIGNAL RECOGNITION PARTICLE 9/14 FUSION PROTEIN (Mus musculus)	4 / 7	LEU A2086 PHE A2017 LEU A2013 PHE A2009	None	0.81A	2eikC-1914A: 0.8 2eikJ-1914A: undetectable	2eikC-1914A: 19.40 2eikJ-1914A: 12.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2EIK_P_CHDP1271_0 (CYTOCHROME C OXIDASE POLYPEPTIDE VIIA-HEART CYTOCHROME C OXIDASE SUBUNIT 3)	1914	SIGNAL RECOGNITION PARTICLE 9/14 FUSION PROTEIN (Mus musculus)	4 / 8	LEU A2086 PHE A2017 LEU A2013 PHE A2009	None	0.83A	2eikP-1914A: 0.8 2eikW-1914A: undetectable	2eikP-1914A: 19.40 2eikW-1914A: 12.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2EIL_C_CHDC271_0 (CYTOCHROME C OXIDASE POLYPEPTIDE VIIA-HEART CYTOCHROME C OXIDASE SUBUNIT 3)	1914	SIGNAL RECOGNITION PARTICLE 9/14 FUSION PROTEIN (Mus musculus)	4 / 8	LEU A2086 PHE A2017 LEU A2013 PHE A2009	None	0.81A	2eilC-1914A: 0.7 2eilJ-1914A: undetectable	2eilC-1914A: 19.40 2eilJ-1914A: 12.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2EIL_P_CHDP1271_0 (CYTOCHROME C OXIDASE POLYPEPTIDE VIIA-HEART CYTOCHROME C OXIDASE SUBUNIT 3)	1914	SIGNAL RECOGNITION PARTICLE 9/14 FUSION PROTEIN (Mus musculus)	4 / 8	LEU A2086 PHE A2017 LEU A2013 PHE A2009	None	0.87A	2eilP-1914A: 0.8 2eilW-1914A: 0.0	2eilP-1914A: 19.40 2eilW-1914A: 12.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2EIL_P_CHDP1271_0 (CYTOCHROME C OXIDASE POLYPEPTIDE VIIA-HEART CYTOCHROME C OXIDASE SUBUNIT 3)	1914	SIGNAL RECOGNITION PARTICLE 9/14 FUSION PROTEIN (Mus musculus)	4 / 8	LYS A2066 PHE A2009 LEU A2013 PHE A2017	None	0.81A	2eilP-1914A: 0.8 2eilW-1914A: 0.0	2eilP-1914A: 19.40 2eilW-1914A: 12.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2EIM_W_CHDW1271_0 (CYTOCHROME C OXIDASE POLYPEPTIDE VIIA-HEART CYTOCHROME C OXIDASE SUBUNIT 3)	1914	SIGNAL RECOGNITION PARTICLE 9/14 FUSION PROTEIN (Mus musculus)	4 / 7	LEU A2086 PHE A2017 LEU A2013 PHE A2009	None	0.88A	2eimP-1914A: undetectable 2eimW-1914A: undetectable	2eimP-1914A: 19.40 2eimW-1914A: 12.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2XN5_A_FUNA1356_1 (THYROXINE-BINDING GLOBULIN)	1914	SIGNAL RECOGNITION PARTICLE 9/14 FUSION PROTEIN (Mus musculus)	5 / 11	SER A4011 ALA A4014 LEU A4038 LEU A4029 LEU A2087	None	1.01A	2xn5A-1914A: 0.0	2xn5A-1914A: 20.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3ABK_P_CHDP1271_0 (CYTOCHROME C OXIDASE POLYPEPTIDE 7A1 CYTOCHROME C OXIDASE SUBUNIT 3)	1914	SIGNAL RECOGNITION PARTICLE 9/14 FUSION PROTEIN (Mus musculus)	4 / 6	LEU A2086 PHE A2017 LEU A2013 PHE A2009	None	0.86A	3abkP-1914A: 0.7 3abkW-1914A: undetectable	3abkP-1914A: 19.40 3abkW-1914A: 12.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3AG2_P_CHDP1271_0 (CYTOCHROME C OXIDASE POLYPEPTIDE 7A1 CYTOCHROME C OXIDASE SUBUNIT 3)	1914	SIGNAL RECOGNITION PARTICLE 9/14 FUSION PROTEIN (Mus musculus)	4 / 7	LEU A2086 PHE A2017 LEU A2013 PHE A2009	None	0.89A	3ag2P-1914A: undetectable 3ag2W-1914A: undetectable	3ag2P-1914A: 19.40 3ag2W-1914A: 12.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3AG4_C_CHDC271_0 (CYTOCHROME C OXIDASE POLYPEPTIDE 7A1 CYTOCHROME C OXIDASE SUBUNIT 3)	1914	SIGNAL RECOGNITION PARTICLE 9/14 FUSION PROTEIN (Mus musculus)	4 / 8	LEU A2086 PHE A2017 LEU A2013 PHE A2009	None	0.84A	3ag4C-1914A: undetectable 3ag4J-1914A: undetectable	3ag4C-1914A: 19.40 3ag4J-1914A: 12.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3AG4_P_CHDP1271_0 (CYTOCHROME C OXIDASE POLYPEPTIDE 7A1 CYTOCHROME C OXIDASE SUBUNIT 3)	1914	SIGNAL RECOGNITION PARTICLE 9/14 FUSION PROTEIN (Mus musculus)	4 / 7	LEU A2086 PHE A2017 LEU A2013 PHE A2009	None	0.82A	3ag4P-1914A: 0.9 3ag4W-1914A: undetectable	3ag4P-1914A: 19.40 3ag4W-1914A: 12.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3ASN_C_CHDC271_0 (CYTOCHROME C OXIDASE SUBUNIT 3 CYTOCHROME C OXIDASE SUBUNIT 7A1)	1914	SIGNAL RECOGNITION PARTICLE 9/14 FUSION PROTEIN (Mus musculus)	4 / 7	LEU A2086 PHE A2017 LEU A2013 PHE A2009	None	0.86A	3asnC-1914A: 0.8 3asnJ-1914A: 0.0	3asnC-1914A: 19.40 3asnJ-1914A: 12.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3ASO_C_CHDC271_0 (CYTOCHROME C OXIDASE SUBUNIT 3 CYTOCHROME C OXIDASE SUBUNIT 7A1)	1914	SIGNAL RECOGNITION PARTICLE 9/14 FUSION PROTEIN (Mus musculus)	4 / 8	LEU A2086 PHE A2017 LEU A2013 PHE A2009	None	0.86A	3asoC-1914A: 0.8 3asoJ-1914A: 0.0	3asoC-1914A: 19.40 3asoJ-1914A: 12.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3ASO_P_CHDP1271_0 (CYTOCHROME C OXIDASE SUBUNIT 3 CYTOCHROME C OXIDASE SUBUNIT 7A1)	1914	SIGNAL RECOGNITION PARTICLE 9/14 FUSION PROTEIN (Mus musculus)	4 / 7	LEU A2086 PHE A2017 LEU A2013 PHE A2009	None	0.83A	3asoP-1914A: undetectable 3asoW-1914A: 0.0	3asoP-1914A: 19.40 3asoW-1914A: 12.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3VW7_A_VPXA2001_1 (PROTEINASE-ACTIVATED RECEPTOR 1, LYSOZYME)	1914	SIGNAL RECOGNITION PARTICLE 9/14 FUSION PROTEIN (Mus musculus)	5 / 12	HIS A4066 LEU A2010 LEU A2013 ALA A2082 TYR A2083	None	1.09A	3vw7A-1914A: 0.0	3vw7A-1914A: 18.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3WG7_C_CHDC305_0 (CYTOCHROME C OXIDASE SUBUNIT 3 CYTOCHROME C OXIDASE SUBUNIT 7A1, MITOCHONDRIAL)	1914	SIGNAL RECOGNITION PARTICLE 9/14 FUSION PROTEIN (Mus musculus)	4 / 6	LEU A2086 PHE A2017 LEU A2013 PHE A2009	None	0.77A	3wg7C-1914A: undetectable 3wg7J-1914A: undetectable	3wg7C-1914A: 19.40 3wg7J-1914A: 12.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3WG7_P_CHDP306_0 (CYTOCHROME C OXIDASE SUBUNIT 3 CYTOCHROME C OXIDASE SUBUNIT 7A1, MITOCHONDRIAL)	1914	SIGNAL RECOGNITION PARTICLE 9/14 FUSION PROTEIN (Mus musculus)	4 / 6	LEU A2086 PHE A2017 LEU A2013 PHE A2009	None	0.93A	3wg7P-1914A: 0.8 3wg7W-1914A: 0.0	3wg7P-1914A: 19.40 3wg7W-1914A: 12.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3X2Q_C_CHDC304_0 (CYTOCHROME C OXIDASE SUBUNIT 3 CYTOCHROME C OXIDASE SUBUNIT 7A1, MITOCHONDRIAL)	1914	SIGNAL RECOGNITION PARTICLE 9/14 FUSION PROTEIN (Mus musculus)	4 / 7	LEU A2086 PHE A2017 LEU A2013 PHE A2009	None	0.82A	3x2qC-1914A: 0.7 3x2qJ-1914A: undetectable	3x2qC-1914A: 19.40 3x2qJ-1914A: 12.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3X2Q_P_CHDP307_0 (CYTOCHROME C OXIDASE SUBUNIT 3 CYTOCHROME C OXIDASE SUBUNIT 7A1, MITOCHONDRIAL)	1914	SIGNAL RECOGNITION PARTICLE 9/14 FUSION PROTEIN (Mus musculus)	4 / 7	LEU A2086 PHE A2017 LEU A2013 PHE A2009	None	0.87A	3x2qP-1914A: undetectable 3x2qW-1914A: 0.0	3x2qP-1914A: 19.40 3x2qW-1914A: 12.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4IIZ_B_LURB201_1 (TRANSTHYRETIN)	1914	SIGNAL RECOGNITION PARTICLE 9/14 FUSION PROTEIN (Mus musculus)	4 / 8	GLU A2012 ALA A2060 LEU A2058 VAL A2026	None	0.89A	4iizB-1914A: undetectable	4iizB-1914A: 18.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4IK6_B_LURB201_1 (TRANSTHYRETIN)	1914	SIGNAL RECOGNITION PARTICLE 9/14 FUSION PROTEIN (Mus musculus)	4 / 8	GLU A2012 ALA A2060 LEU A2058 VAL A2026	None	0.88A	4ik6B-1914A: 1.0	4ik6B-1914A: 18.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4XYZ_A_ACTA103_0 (POLYUBIQUITIN-C)	1914	SIGNAL RECOGNITION PARTICLE 9/14 FUSION PROTEIN (Mus musculus)	4 / 4	LEU A4069 ILE A4040 HIS A4066 VAL A4042	None	1.03A	4xyzA-1914A: undetectable	4xyzA-1914A: 18.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5B1A_C_CHDC304_0 (CYTOCHROME C OXIDASE SUBUNIT 3 CYTOCHROME C OXIDASE SUBUNIT 7A1, MITOCHONDRIAL)	1914	SIGNAL RECOGNITION PARTICLE 9/14 FUSION PROTEIN (Mus musculus)	4 / 7	LEU A2086 PHE A2017 LEU A2013 PHE A2009	None	0.85A	5b1aC-1914A: 0.7 5b1aJ-1914A: 0.0	5b1aC-1914A: 19.40 5b1aJ-1914A: 12.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5B1A_P_CHDP305_0 (CYTOCHROME C OXIDASE SUBUNIT 3 CYTOCHROME C OXIDASE SUBUNIT 7A1, MITOCHONDRIAL)	1914	SIGNAL RECOGNITION PARTICLE 9/14 FUSION PROTEIN (Mus musculus)	4 / 7	LEU A2086 PHE A2017 LEU A2013 PHE A2009	None	0.82A	5b1aP-1914A: 0.8 5b1aW-1914A: undetectable	5b1aP-1914A: 19.40 5b1aW-1914A: 12.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5B1B_P_CHDP306_0 (CYTOCHROME C OXIDASE SUBUNIT 3 CYTOCHROME C OXIDASE SUBUNIT 7A1, MITOCHONDRIAL)	1914	SIGNAL RECOGNITION PARTICLE 9/14 FUSION PROTEIN (Mus musculus)	4 / 7	LEU A2086 PHE A2017 LEU A2013 PHE A2009	None	0.87A	5b1bP-1914A: 0.8 5b1bW-1914A: undetectable	5b1bP-1914A: 19.40 5b1bW-1914A: 12.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5B3S_C_CHDC307_0 (CYTOCHROME C OXIDASE SUBUNIT 3 CYTOCHROME C OXIDASE SUBUNIT 7A1, MITOCHONDRIAL)	1914	SIGNAL RECOGNITION PARTICLE 9/14 FUSION PROTEIN (Mus musculus)	4 / 7	LEU A2086 PHE A2017 LEU A2013 PHE A2009	None	0.92A	5b3sC-1914A: undetectable 5b3sJ-1914A: undetectable	5b3sC-1914A: 19.40 5b3sJ-1914A: 12.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5IY5_C_CHDC307_0 (CYTOCHROME C OXIDASE SUBUNIT 3 CYTOCHROME C OXIDASE SUBUNIT 7A1, MITOCHONDRIAL)	1914	SIGNAL RECOGNITION PARTICLE 9/14 FUSION PROTEIN (Mus musculus)	4 / 7	LEU A2086 PHE A2017 LEU A2013 PHE A2009	None	0.84A	5iy5C-1914A: 0.7 5iy5J-1914A: 0.0	5iy5C-1914A: 19.03 5iy5J-1914A: 12.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5X19_C_CHDC304_0 (CYTOCHROME C OXIDASE SUBUNIT 3 CYTOCHROME C OXIDASE SUBUNIT 7A1, MITOCHONDRIAL)	1914	SIGNAL RECOGNITION PARTICLE 9/14 FUSION PROTEIN (Mus musculus)	4 / 5	LEU A2086 PHE A2017 LEU A2013 PHE A2009	None	0.90A	5x19C-1914A: 0.8 5x19J-1914A: 0.0	5x19C-1914A: 19.40 5x19J-1914A: 12.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5X1F_P_CHDP304_0 (CYTOCHROME C OXIDASE SUBUNIT 3 CYTOCHROME C OXIDASE SUBUNIT 7A1, MITOCHONDRIAL)	1914	SIGNAL RECOGNITION PARTICLE 9/14 FUSION PROTEIN (Mus musculus)	4 / 7	LEU A2086 PHE A2017 LEU A2013 PHE A2009	None	0.81A	5x1fP-1914A: undetectable 5x1fW-1914A: 0.0	5x1fP-1914A: 19.40 5x1fW-1914A: 12.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5Z84_C_CHDC307_0 (CYTOCHROME C OXIDASE SUBUNIT 3 CYTOCHROME C OXIDASE SUBUNIT 7A1, MITOCHONDRIAL)	1914	SIGNAL RECOGNITION PARTICLE 9/14 FUSION PROTEIN (Mus musculus)	4 / 7	LEU A2086 PHE A2017 LEU A2013 PHE A2009	None	0.90A	5z84C-1914A: 0.7 5z84J-1914A: 0.0	5z84C-1914A: 19.40 5z84J-1914A: 12.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5Z85_C_CHDC306_0 (CYTOCHROME C OXIDASE SUBUNIT 3 CYTOCHROME C OXIDASE SUBUNIT 7A1, MITOCHONDRIAL)	1914	SIGNAL RECOGNITION PARTICLE 9/14 FUSION PROTEIN (Mus musculus)	4 / 7	LEU A2086 PHE A2017 LEU A2013 PHE A2009	None	0.92A	5z85C-1914A: 0.7 5z85J-1914A: undetectable	5z85C-1914A: 19.40 5z85J-1914A: 12.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5ZCO_C_CHDC306_0 (CYTOCHROME C OXIDASE SUBUNIT 3 CYTOCHROME C OXIDASE SUBUNIT 7A1, MITOCHONDRIAL)	1914	SIGNAL RECOGNITION PARTICLE 9/14 FUSION PROTEIN (Mus musculus)	4 / 7	LEU A2086 PHE A2017 LEU A2013 PHE A2009	None	0.90A	5zcoC-1914A: 0.8 5zcoJ-1914A: undetectable	5zcoC-1914A: 19.40 5zcoJ-1914A: 12.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5ZCQ_P_CHDP306_0 (CYTOCHROME C OXIDASE SUBUNIT 3 CYTOCHROME C OXIDASE SUBUNIT 7A1, MITOCHONDRIAL)	1914	SIGNAL RECOGNITION PARTICLE 9/14 FUSION PROTEIN (Mus musculus)	4 / 7	LEU A2086 PHE A2017 LEU A2013 PHE A2009	None	0.92A	5zcqP-1914A: 0.8 5zcqW-1914A: 0.0	5zcqP-1914A: 19.40 5zcqW-1914A: 12.86

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1J8U_A_H4BA429_1","PHENYLALANINE-4-HYDROXYLASE","1914","SIGNAL RECOGNITION PARTICLE 9\/14 FUSION PROTEIN","Mus musculus",4,"LEU A2004;SER A2006;PHE A2009;LEU A2010","None","0.41A","1j8uA-1914A:undetectable","1j8uA-1914A:20.06"],["1KW0_A_H4BA429_1","PHENYLALANINE-4-HYDROXYLASE","1914","SIGNAL RECOGNITION PARTICLE 9\/14 FUSION PROTEIN","Mus musculus",5,"VAL A2002;LEU A2004;SER A2006;PHE A2009;LEU A2010","None","0.98A","1kw0A-1914A:undetectable","1kw0A-1914A:20.06"],["1MMK_A_H4BA1427_1","PHENYLALANINE-4-HYDROXYLASE","1914","SIGNAL RECOGNITION PARTICLE 9\/14 FUSION PROTEIN","Mus musculus",5,"VAL A2002;LEU A2004;SER A2006;PHE A2009;LEU A2010","None","0.92A","1mmkA-1914A:undetectable","1mmkA-1914A:20.06"],["1MMT_A_H4BA1426_1","PHENYLALANINE-4-HYDROXYLASE","1914","SIGNAL RECOGNITION PARTICLE 9\/14 FUSION PROTEIN","Mus musculus",5,"VAL A2002;LEU A2004;SER A2006;PHE A2009;LEU A2010","None","0.91A","1mmtA-1914A:undetectable","1mmtA-1914A:20.06"],["1V54_C_CHDC3271_0","CYTOCHROME C OXIDASE POLYPEPTIDE III;CYTOCHROME C OXIDASE POLYPEPTIDE VIIA-HEART","1914","SIGNAL RECOGNITION PARTICLE 9\/14 FUSION PROTEIN","Mus musculus",4,"LEU A2086;PHE A2017;LEU A2013;PHE A2009","None","0.84A","1v54C-1914A:0.8;1v54J-1914A:undetectable","1v54C-1914A:19.40;1v54J-1914A:12.86"],["2DYR_C_CHDC271_0","CYTOCHROME C OXIDASE POLYPEPTIDE VIIA-HEART;CYTOCHROME C OXIDASE SUBUNIT 3","1914","SIGNAL RECOGNITION PARTICLE 9\/14 FUSION PROTEIN","Mus musculus",4,"LEU A2086;PHE A2017;LEU A2013;PHE A2009","None","0.84A","2dyrC-1914A:0.7;2dyrJ-1914A:undetectable","2dyrC-1914A:19.40;2dyrJ-1914A:12.86"],["2DYR_P_CHDP1271_0","CYTOCHROME C OXIDASE POLYPEPTIDE VIIA-HEART;CYTOCHROME C OXIDASE SUBUNIT 3","1914","SIGNAL RECOGNITION PARTICLE 9\/14 FUSION PROTEIN","Mus musculus",4,"LEU A2086;PHE A2017;LEU A2013;PHE A2009","None","0.86A","2dyrP-1914A:0.8;2dyrW-1914A:undetectable","2dyrP-1914A:19.40;2dyrW-1914A:12.86"],["2EIK_C_CHDC271_0","CYTOCHROME C OXIDASE POLYPEPTIDE VIIA-HEART;CYTOCHROME C OXIDASE SUBUNIT 3","1914","SIGNAL RECOGNITION PARTICLE 9\/14 FUSION PROTEIN","Mus musculus",4,"LEU A2086;PHE A2017;LEU A2013;PHE A2009","None","0.81A","2eikC-1914A:0.8;2eikJ-1914A:undetectable","2eikC-1914A:19.40;2eikJ-1914A:12.86"],["2EIK_P_CHDP1271_0","CYTOCHROME C OXIDASE POLYPEPTIDE VIIA-HEART;CYTOCHROME C OXIDASE SUBUNIT 3","1914","SIGNAL RECOGNITION PARTICLE 9\/14 FUSION PROTEIN","Mus musculus",4,"LEU A2086;PHE A2017;LEU A2013;PHE A2009","None","0.83A","2eikP-1914A:0.8;2eikW-1914A:undetectable","2eikP-1914A:19.40;2eikW-1914A:12.86"],["2EIL_C_CHDC271_0","CYTOCHROME C OXIDASE POLYPEPTIDE VIIA-HEART;CYTOCHROME C OXIDASE SUBUNIT 3","1914","SIGNAL RECOGNITION PARTICLE 9\/14 FUSION PROTEIN","Mus musculus",4,"LEU A2086;PHE A2017;LEU A2013;PHE A2009","None","0.81A","2eilC-1914A:0.7;2eilJ-1914A:undetectable","2eilC-1914A:19.40;2eilJ-1914A:12.86"],["2EIL_P_CHDP1271_0","CYTOCHROME C OXIDASE POLYPEPTIDE VIIA-HEART;CYTOCHROME C OXIDASE SUBUNIT 3","1914","SIGNAL RECOGNITION PARTICLE 9\/14 FUSION PROTEIN","Mus musculus",4,"LEU A2086;PHE A2017;LEU A2013;PHE A2009","None","0.87A","2eilP-1914A:0.8;2eilW-1914A:0.0","2eilP-1914A:19.40;2eilW-1914A:12.86"],["2EIL_P_CHDP1271_0","CYTOCHROME C OXIDASE POLYPEPTIDE VIIA-HEART;CYTOCHROME C OXIDASE SUBUNIT 3","1914","SIGNAL RECOGNITION PARTICLE 9\/14 FUSION PROTEIN","Mus musculus",4,"LYS A2066;PHE A2009;LEU A2013;PHE A2017","None","0.81A","2eilP-1914A:0.8;2eilW-1914A:0.0","2eilP-1914A:19.40;2eilW-1914A:12.86"],["2EIM_W_CHDW1271_0","CYTOCHROME C OXIDASE POLYPEPTIDE VIIA-HEART;CYTOCHROME C OXIDASE SUBUNIT 3","1914","SIGNAL RECOGNITION PARTICLE 9\/14 FUSION PROTEIN","Mus musculus",4,"LEU A2086;PHE A2017;LEU A2013;PHE A2009","None","0.88A","2eimP-1914A:undetectable;2eimW-1914A:undetectable","2eimP-1914A:19.40;2eimW-1914A:12.86"],["2XN5_A_FUNA1356_1","THYROXINE-BINDING GLOBULIN","1914","SIGNAL RECOGNITION PARTICLE 9\/14 FUSION PROTEIN","Mus musculus",5,"SER A4011;ALA A4014;LEU A4038;LEU A4029;LEU A2087","None","1.01A","2xn5A-1914A:0.0","2xn5A-1914A:20.12"],["3ABK_P_CHDP1271_0","CYTOCHROME C OXIDASE POLYPEPTIDE 7A1;CYTOCHROME C OXIDASE SUBUNIT 3","1914","SIGNAL RECOGNITION PARTICLE 9\/14 FUSION PROTEIN","Mus musculus",4,"LEU A2086;PHE A2017;LEU A2013;PHE A2009","None","0.86A","3abkP-1914A:0.7;3abkW-1914A:undetectable","3abkP-1914A:19.40;3abkW-1914A:12.86"],["3AG2_P_CHDP1271_0","CYTOCHROME C OXIDASE POLYPEPTIDE 7A1;CYTOCHROME C OXIDASE SUBUNIT 3","1914","SIGNAL RECOGNITION PARTICLE 9\/14 FUSION PROTEIN","Mus musculus",4,"LEU A2086;PHE A2017;LEU A2013;PHE A2009","None","0.89A","3ag2P-1914A:undetectable;3ag2W-1914A:undetectable","3ag2P-1914A:19.40;3ag2W-1914A:12.86"],["3AG4_C_CHDC271_0","CYTOCHROME C OXIDASE POLYPEPTIDE 7A1;CYTOCHROME C OXIDASE SUBUNIT 3","1914","SIGNAL RECOGNITION PARTICLE 9\/14 FUSION PROTEIN","Mus musculus",4,"LEU A2086;PHE A2017;LEU A2013;PHE A2009","None","0.84A","3ag4C-1914A:undetectable;3ag4J-1914A:undetectable","3ag4C-1914A:19.40;3ag4J-1914A:12.86"],["3AG4_P_CHDP1271_0","CYTOCHROME C OXIDASE POLYPEPTIDE 7A1;CYTOCHROME C OXIDASE SUBUNIT 3","1914","SIGNAL RECOGNITION PARTICLE 9\/14 FUSION PROTEIN","Mus musculus",4,"LEU A2086;PHE A2017;LEU A2013;PHE A2009","None","0.82A","3ag4P-1914A:0.9;3ag4W-1914A:undetectable","3ag4P-1914A:19.40;3ag4W-1914A:12.86"],["3ASN_C_CHDC271_0","CYTOCHROME C OXIDASE SUBUNIT 3;CYTOCHROME C OXIDASE SUBUNIT 7A1","1914","SIGNAL RECOGNITION PARTICLE 9\/14 FUSION PROTEIN","Mus musculus",4,"LEU A2086;PHE A2017;LEU A2013;PHE A2009","None","0.86A","3asnC-1914A:0.8;3asnJ-1914A:0.0","3asnC-1914A:19.40;3asnJ-1914A:12.86"],["3ASO_C_CHDC271_0","CYTOCHROME C OXIDASE SUBUNIT 3;CYTOCHROME C OXIDASE SUBUNIT 7A1","1914","SIGNAL RECOGNITION PARTICLE 9\/14 FUSION PROTEIN","Mus musculus",4,"LEU A2086;PHE A2017;LEU A2013;PHE A2009","None","0.86A","3asoC-1914A:0.8;3asoJ-1914A:0.0","3asoC-1914A:19.40;3asoJ-1914A:12.86"],["3ASO_P_CHDP1271_0","CYTOCHROME C OXIDASE SUBUNIT 3;CYTOCHROME C OXIDASE SUBUNIT 7A1","1914","SIGNAL RECOGNITION PARTICLE 9\/14 FUSION PROTEIN","Mus musculus",4,"LEU A2086;PHE A2017;LEU A2013;PHE A2009","None","0.83A","3asoP-1914A:undetectable;3asoW-1914A:0.0","3asoP-1914A:19.40;3asoW-1914A:12.86"],["3VW7_A_VPXA2001_1","PROTEINASE-ACTIVATED RECEPTOR 1, LYSOZYME","1914","SIGNAL RECOGNITION PARTICLE 9\/14 FUSION PROTEIN","Mus musculus",5,"HIS A4066;LEU A2010;LEU A2013;ALA A2082;TYR A2083","None","1.09A","3vw7A-1914A:0.0","3vw7A-1914A:18.96"],["3WG7_C_CHDC305_0","CYTOCHROME C OXIDASE SUBUNIT 3;CYTOCHROME C OXIDASE SUBUNIT 7A1, MITOCHONDRIAL","1914","SIGNAL RECOGNITION PARTICLE 9\/14 FUSION PROTEIN","Mus musculus",4,"LEU A2086;PHE A2017;LEU A2013;PHE A2009","None","0.77A","3wg7C-1914A:undetectable;3wg7J-1914A:undetectable","3wg7C-1914A:19.40;3wg7J-1914A:12.86"],["3WG7_P_CHDP306_0","CYTOCHROME C OXIDASE SUBUNIT 3;CYTOCHROME C OXIDASE SUBUNIT 7A1, MITOCHONDRIAL","1914","SIGNAL RECOGNITION PARTICLE 9\/14 FUSION PROTEIN","Mus musculus",4,"LEU A2086;PHE A2017;LEU A2013;PHE A2009","None","0.93A","3wg7P-1914A:0.8;3wg7W-1914A:0.0","3wg7P-1914A:19.40;3wg7W-1914A:12.86"],["3X2Q_C_CHDC304_0","CYTOCHROME C OXIDASE SUBUNIT 3;CYTOCHROME C OXIDASE SUBUNIT 7A1, MITOCHONDRIAL","1914","SIGNAL RECOGNITION PARTICLE 9\/14 FUSION PROTEIN","Mus musculus",4,"LEU A2086;PHE A2017;LEU A2013;PHE A2009","None","0.82A","3x2qC-1914A:0.7;3x2qJ-1914A:undetectable","3x2qC-1914A:19.40;3x2qJ-1914A:12.86"],["3X2Q_P_CHDP307_0","CYTOCHROME C OXIDASE SUBUNIT 3;CYTOCHROME C OXIDASE SUBUNIT 7A1, MITOCHONDRIAL","1914","SIGNAL RECOGNITION PARTICLE 9\/14 FUSION PROTEIN","Mus musculus",4,"LEU A2086;PHE A2017;LEU A2013;PHE A2009","None","0.87A","3x2qP-1914A:undetectable;3x2qW-1914A:0.0","3x2qP-1914A:19.40;3x2qW-1914A:12.86"],["4IIZ_B_LURB201_1","TRANSTHYRETIN","1914","SIGNAL RECOGNITION PARTICLE 9\/14 FUSION PROTEIN","Mus musculus",4,"GLU A2012;ALA A2060;LEU A2058;VAL A2026","None","0.89A","4iizB-1914A:undetectable","4iizB-1914A:18.97"],["4IK6_B_LURB201_1","TRANSTHYRETIN","1914","SIGNAL RECOGNITION PARTICLE 9\/14 FUSION PROTEIN","Mus musculus",4,"GLU A2012;ALA A2060;LEU A2058;VAL A2026","None","0.88A","4ik6B-1914A:1.0","4ik6B-1914A:18.97"],["4XYZ_A_ACTA103_0","POLYUBIQUITIN-C","1914","SIGNAL RECOGNITION PARTICLE 9\/14 FUSION PROTEIN","Mus musculus",4,"LEU A4069;ILE A4040;HIS A4066;VAL A4042","None","1.03A","4xyzA-1914A:undetectable","4xyzA-1914A:18.06"],["5B1A_C_CHDC304_0","CYTOCHROME C OXIDASE SUBUNIT 3;CYTOCHROME C OXIDASE SUBUNIT 7A1, MITOCHONDRIAL","1914","SIGNAL RECOGNITION PARTICLE 9\/14 FUSION PROTEIN","Mus musculus",4,"LEU A2086;PHE A2017;LEU A2013;PHE A2009","None","0.85A","5b1aC-1914A:0.7;5b1aJ-1914A:0.0","5b1aC-1914A:19.40;5b1aJ-1914A:12.86"],["5B1A_P_CHDP305_0","CYTOCHROME C OXIDASE SUBUNIT 3;CYTOCHROME C OXIDASE SUBUNIT 7A1, MITOCHONDRIAL","1914","SIGNAL RECOGNITION PARTICLE 9\/14 FUSION PROTEIN","Mus musculus",4,"LEU A2086;PHE A2017;LEU A2013;PHE A2009","None","0.82A","5b1aP-1914A:0.8;5b1aW-1914A:undetectable","5b1aP-1914A:19.40;5b1aW-1914A:12.86"],["5B1B_P_CHDP306_0","CYTOCHROME C OXIDASE SUBUNIT 3;CYTOCHROME C OXIDASE SUBUNIT 7A1, MITOCHONDRIAL","1914","SIGNAL RECOGNITION PARTICLE 9\/14 FUSION PROTEIN","Mus musculus",4,"LEU A2086;PHE A2017;LEU A2013;PHE A2009","None","0.87A","5b1bP-1914A:0.8;5b1bW-1914A:undetectable","5b1bP-1914A:19.40;5b1bW-1914A:12.86"],["5B3S_C_CHDC307_0","CYTOCHROME C OXIDASE SUBUNIT 3;CYTOCHROME C OXIDASE SUBUNIT 7A1, MITOCHONDRIAL","1914","SIGNAL RECOGNITION PARTICLE 9\/14 FUSION PROTEIN","Mus musculus",4,"LEU A2086;PHE A2017;LEU A2013;PHE A2009","None","0.92A","5b3sC-1914A:undetectable;5b3sJ-1914A:undetectable","5b3sC-1914A:19.40;5b3sJ-1914A:12.86"],["5IY5_C_CHDC307_0","CYTOCHROME C OXIDASE SUBUNIT 3;CYTOCHROME C OXIDASE SUBUNIT 7A1, MITOCHONDRIAL","1914","SIGNAL RECOGNITION PARTICLE 9\/14 FUSION PROTEIN","Mus musculus",4,"LEU A2086;PHE A2017;LEU A2013;PHE A2009","None","0.84A","5iy5C-1914A:0.7;5iy5J-1914A:0.0","5iy5C-1914A:19.03;5iy5J-1914A:12.56"],["5X19_C_CHDC304_0","CYTOCHROME C OXIDASE SUBUNIT 3;CYTOCHROME C OXIDASE SUBUNIT 7A1, MITOCHONDRIAL","1914","SIGNAL RECOGNITION PARTICLE 9\/14 FUSION PROTEIN","Mus musculus",4,"LEU A2086;PHE A2017;LEU A2013;PHE A2009","None","0.90A","5x19C-1914A:0.8;5x19J-1914A:0.0","5x19C-1914A:19.40;5x19J-1914A:12.86"],["5X1F_P_CHDP304_0","CYTOCHROME C OXIDASE SUBUNIT 3;CYTOCHROME C OXIDASE SUBUNIT 7A1, MITOCHONDRIAL","1914","SIGNAL RECOGNITION PARTICLE 9\/14 FUSION PROTEIN","Mus musculus",4,"LEU A2086;PHE A2017;LEU A2013;PHE A2009","None","0.81A","5x1fP-1914A:undetectable;5x1fW-1914A:0.0","5x1fP-1914A:19.40;5x1fW-1914A:12.86"],["5Z84_C_CHDC307_0","CYTOCHROME C OXIDASE SUBUNIT 3;CYTOCHROME C OXIDASE SUBUNIT 7A1, MITOCHONDRIAL","1914","SIGNAL RECOGNITION PARTICLE 9\/14 FUSION PROTEIN","Mus musculus",4,"LEU A2086;PHE A2017;LEU A2013;PHE A2009","None","0.90A","5z84C-1914A:0.7;5z84J-1914A:0.0","5z84C-1914A:19.40;5z84J-1914A:12.86"],["5Z85_C_CHDC306_0","CYTOCHROME C OXIDASE SUBUNIT 3;CYTOCHROME C OXIDASE SUBUNIT 7A1, MITOCHONDRIAL","1914","SIGNAL RECOGNITION PARTICLE 9\/14 FUSION PROTEIN","Mus musculus",4,"LEU A2086;PHE A2017;LEU A2013;PHE A2009","None","0.92A","5z85C-1914A:0.7;5z85J-1914A:undetectable","5z85C-1914A:19.40;5z85J-1914A:12.86"],["5ZCO_C_CHDC306_0","CYTOCHROME C OXIDASE SUBUNIT 3;CYTOCHROME C OXIDASE SUBUNIT 7A1, MITOCHONDRIAL","1914","SIGNAL RECOGNITION PARTICLE 9\/14 FUSION PROTEIN","Mus musculus",4,"LEU A2086;PHE A2017;LEU A2013;PHE A2009","None","0.90A","5zcoC-1914A:0.8;5zcoJ-1914A:undetectable","5zcoC-1914A:19.40;5zcoJ-1914A:12.86"],["5ZCQ_P_CHDP306_0","CYTOCHROME C OXIDASE SUBUNIT 3;CYTOCHROME C OXIDASE SUBUNIT 7A1, MITOCHONDRIAL","1914","SIGNAL RECOGNITION PARTICLE 9\/14 FUSION PROTEIN","Mus musculus",4,"LEU A2086;PHE A2017;LEU A2013;PHE A2009","None","0.92A","5zcqP-1914A:0.8;5zcqW-1914A:0.0","5zcqP-1914A:19.40;5zcqW-1914A:12.86"]]