SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '19hc'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1S9P_B_DESB459_2 (ESTROGEN-RELATED RECEPTOR GAMMA)	19hc	PROTEIN (NINE-HAEM CYTOCHROME C) (Desulfovibrio desulfuricans)	3 / 3	LEU A 213 HIS A 218 ILE A 208	HEM A 303 (-3.8A) HEM A 304 (-3.2A) HEM A 304 (-4.1A)	0.65A	1s9pB-19hcA: undetectable	1s9pB-19hcA: 24.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3GWX_A_EPAA1_2 (PROTEIN (PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR (PPAR-DELTA)))	19hc	PROTEIN (NINE-HAEM CYTOCHROME C) (Desulfovibrio desulfuricans)	5 / 12	CYH A 114 THR A 118 THR A 119 ILE A 208 HIS A 218	HEM A 304 ( 1.8A) HEM A 304 (-3.2A) None HEM A 304 (-4.1A) HEM A 304 (-3.2A)	1.19A	3gwxA-19hcA: undetectable	3gwxA-19hcA: 21.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3QEL_D_QELD2_2 (GLUTAMATE [NMDA] RECEPTOR SUBUNIT EPSILON-2)	19hc	PROTEIN (NINE-HAEM CYTOCHROME C) (Desulfovibrio desulfuricans)	5 / 9	PRO A 11 ALA A 159 PHE A 35 THR A 138 GLU A 141	ACT A 293 (-4.4A) None HEM A 301 ( 3.8A) None None	1.34A	3qelD-19hcA: undetectable	3qelD-19hcA: 22.02

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1S9P_B_DESB459_2","ESTROGEN-RELATED RECEPTOR GAMMA","19hc","PROTEIN (NINE-HAEM CYTOCHROME C)","Desulfovibrio desulfuricans",3,"LEU A 213;HIS A 218;ILE A 208","HEM A 303 (-3.8A);HEM A 304 (-3.2A);HEM A 304 (-4.1A)","0.65A","1s9pB-19hcA:undetectable","1s9pB-19hcA:24.11"],["3GWX_A_EPAA1_2","PROTEIN (PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR (PPAR-DELTA))","19hc","PROTEIN (NINE-HAEM CYTOCHROME C)","Desulfovibrio desulfuricans",5,"CYH A 114;THR A 118;THR A 119;ILE A 208;HIS A 218","HEM A 304 ( 1.8A);HEM A 304 (-3.2A);None;HEM A 304 (-4.1A);HEM A 304 (-3.2A)","1.19A","3gwxA-19hcA:undetectable","3gwxA-19hcA:21.82"],["3QEL_D_QELD2_2","GLUTAMATE [NMDA] RECEPTOR SUBUNIT EPSILON-2","19hc","PROTEIN (NINE-HAEM CYTOCHROME C)","Desulfovibrio desulfuricans",5,"PRO A  11;ALA A 159;PHE A  35;THR A 138;GLU A 141","ACT A 293 (-4.4A);None;HEM A 301 ( 3.8A);None;None","1.34A","3qelD-19hcA:undetectable","3qelD-19hcA:22.02"]]