SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1a0p'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1U1J_A_C2FA773_0
(5-METHYLTETRAHYDROPT
EROYLTRIGLUTAMATE--H
OMOCYSTEINE
METHYLTRANSFERASE)		 1a0p SITE-SPECIFIC
RECOMBINASE XERD
(Escherichia
coli) 		4 / 8 ARG A 247
SER A 242
ARG A  88
VAL A 245
 None
 1.08A 1u1jA-1a0pA:
undetectable		 1u1jA-1a0pA:
17.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V8B_A_ADNA502_2
(ADENOSYLHOMOCYSTEINA
SE)		 1a0p SITE-SPECIFIC
RECOMBINASE XERD
(Escherichia
coli) 		3 / 3 GLU A 184
GLU A 190
LEU A 133
 None
 0.51A 1v8bA-1a0pA:
undetectable		 1v8bA-1a0pA:
20.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V8B_B_ADNB1502_2
(ADENOSYLHOMOCYSTEINA
SE)		 1a0p SITE-SPECIFIC
RECOMBINASE XERD
(Escherichia
coli) 		3 / 3 GLU A 184
GLU A 190
LEU A 133
 None
 0.47A 1v8bB-1a0pA:
undetectable		 1v8bB-1a0pA:
20.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YA3_A_STRA1001_2
(MINERALOCORTICOID
RECEPTOR)		 1a0p SITE-SPECIFIC
RECOMBINASE XERD
(Escherichia
coli) 		4 / 4 LEU A  40
LEU A  33
SER A  34
LEU A   5
 None
 1.18A 1ya3A-1a0pA:
0.2		 1ya3A-1a0pA:
22.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PGZ_D_COCD401_1
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)		 1a0p SITE-SPECIFIC
RECOMBINASE XERD
(Escherichia
coli) 		4 / 6 TYR A 143
TYR A 279
GLN A 277
ILE A 278
 None
 1.46A 2pgzD-1a0pA:
0.0
2pgzE-1a0pA:
0.0		 2pgzD-1a0pA:
20.34
2pgzE-1a0pA:
20.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X7H_B_PFNB1374_1
(ZINC-BINDING ALCOHOL
DEHYDROGENASE
DOMAIN-CONTAINING
PROTEIN 2)		 1a0p SITE-SPECIFIC
RECOMBINASE XERD
(Escherichia
coli) 		4 / 4 TYR A 143
LEU A 139
LEU A 122
HIS A 253
 None
 1.43A 2x7hB-1a0pA:
undetectable		 2x7hB-1a0pA:
22.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ELZ_B_CHDB152_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 1a0p SITE-SPECIFIC
RECOMBINASE XERD
(Escherichia
coli) 		3 / 3 ASN A 256
HIS A 253
VAL A 118
 None
 0.88A 3elzB-1a0pA:
0.0		 3elzB-1a0pA:
18.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HCN_B_CHDB2_0
(FERROCHELATASE,
MITOCHONDRIAL)		 1a0p SITE-SPECIFIC
RECOMBINASE XERD
(Escherichia
coli) 		3 / 3 LEU A 142
LEU A 139
ARG A 134
 None
 0.67A 3hcnB-1a0pA:
undetectable		 3hcnB-1a0pA:
23.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QEL_B_QELB1_1
(NMDA GLUTAMATE
RECEPTOR SUBUNIT
GLUTAMATE [NMDA]
RECEPTOR SUBUNIT
EPSILON-2)		 1a0p SITE-SPECIFIC
RECOMBINASE XERD
(Escherichia
coli) 		5 / 11 ALA A   6
GLN A  10
ILE A   8
PHE A  11
THR A 284
 None
 1.33A 3qelA-1a0pA:
undetectable
3qelB-1a0pA:
undetectable		 3qelA-1a0pA:
21.21
3qelB-1a0pA:
18.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QEL_B_QELB1_1
(NMDA GLUTAMATE
RECEPTOR SUBUNIT
GLUTAMATE [NMDA]
RECEPTOR SUBUNIT
EPSILON-2)		 1a0p SITE-SPECIFIC
RECOMBINASE XERD
(Escherichia
coli) 		5 / 11 TYR A  85
ALA A   6
GLN A  10
ILE A   8
PHE A  11
 None
 1.30A 3qelA-1a0pA:
undetectable
3qelB-1a0pA:
undetectable		 3qelA-1a0pA:
21.21
3qelB-1a0pA:
18.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QEL_D_QELD2_2
(GLUTAMATE [NMDA]
RECEPTOR SUBUNIT
EPSILON-2)		 1a0p SITE-SPECIFIC
RECOMBINASE XERD
(Escherichia
coli) 		5 / 9 ALA A   6
GLN A  10
ILE A   8
PHE A  11
THR A 284
 None
 1.29A 3qelD-1a0pA:
undetectable		 3qelD-1a0pA:
18.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PE5_B_QELB920_1
(GLUTAMATE RECEPTOR
IONOTROPIC, NMDA 1
GLUTAMATE RECEPTOR
IONOTROPIC, NMDA 2B)		 1a0p SITE-SPECIFIC
RECOMBINASE XERD
(Escherichia
coli) 		5 / 10 TYR A  85
ALA A   6
GLN A  10
ILE A   8
PHE A  11
 None
 1.26A 4pe5A-1a0pA:
undetectable
4pe5B-1a0pA:
undetectable		 4pe5A-1a0pA:
17.19
4pe5B-1a0pA:
15.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PE5_C_QELC939_1
(GLUTAMATE RECEPTOR
IONOTROPIC, NMDA 1
GLUTAMATE RECEPTOR
IONOTROPIC, NMDA 2B)		 1a0p SITE-SPECIFIC
RECOMBINASE XERD
(Escherichia
coli) 		5 / 10 TYR A  85
ALA A   6
GLN A  10
ILE A   8
PHE A  11
 None
 1.27A 4pe5C-1a0pA:
undetectable
4pe5D-1a0pA:
undetectable		 4pe5C-1a0pA:
17.19
4pe5D-1a0pA:
15.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EWJ_B_QELB503_1
(NMDA GLUTAMATE
RECEPTOR SUBUNIT
GLUTAMATE RECEPTOR
IONOTROPIC, NMDA 2B)		 1a0p SITE-SPECIFIC
RECOMBINASE XERD
(Escherichia
coli) 		5 / 11 TYR A  85
ALA A   6
GLN A  10
ILE A   8
PHE A  11
 None
 1.28A 5ewjA-1a0pA:
undetectable
5ewjB-1a0pA:
undetectable		 5ewjA-1a0pA:
20.87
5ewjB-1a0pA:
18.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EWJ_D_QELD503_1
(NMDA GLUTAMATE
RECEPTOR SUBUNIT
GLUTAMATE RECEPTOR
IONOTROPIC, NMDA 2B)		 1a0p SITE-SPECIFIC
RECOMBINASE XERD
(Escherichia
coli) 		5 / 12 ALA A   6
GLN A  10
ILE A   8
PHE A  11
THR A 284
 None
 1.35A 5ewjC-1a0pA:
undetectable
5ewjD-1a0pA:
undetectable		 5ewjC-1a0pA:
20.87
5ewjD-1a0pA:
18.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EWJ_D_QELD503_1
(NMDA GLUTAMATE
RECEPTOR SUBUNIT
GLUTAMATE RECEPTOR
IONOTROPIC, NMDA 2B)		 1a0p SITE-SPECIFIC
RECOMBINASE XERD
(Escherichia
coli) 		5 / 12 TYR A  85
ALA A   6
GLN A  10
ILE A   8
PHE A  11
 None
 1.27A 5ewjC-1a0pA:
undetectable
5ewjD-1a0pA:
undetectable		 5ewjC-1a0pA:
20.87
5ewjD-1a0pA:
18.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JQB_B_IBPB706_1
(ENVELOPE
GLYCOPROTEIN
1,ENVELOPE
GLYCOPROTEIN
1,ENVELOPE
GLYCOPROTEIN 1
ENVELOPE
GLYCOPROTEIN 2)		 1a0p SITE-SPECIFIC
RECOMBINASE XERD
(Escherichia
coli) 		5 / 8 ALA A 137
LEU A 181
LEU A 193
TYR A 192
LEU A 162
 None
 1.47A 5jqbA-1a0pA:
0.0
5jqbB-1a0pA:
0.2		 5jqbA-1a0pA:
23.88
5jqbB-1a0pA:
20.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TRQ_B_ACTB307_0
(WELO5)		 1a0p SITE-SPECIFIC
RECOMBINASE XERD
(Escherichia
coli) 		3 / 3 GLU A 285
HIS A 281
VAL A 264
 None
 0.41A 5trqB-1a0pA:
undetectable		 5trqB-1a0pA:
21.69