SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1a17'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVN_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 1a17 SERINE/THREONINE
PROTEIN PHOSPHATASE
5
(Homo
sapiens) 		5 / 10 SER A 105
GLY A  83
THR A  86
ALA A  85
ASP A 118
 None
 1.22A 4qvnV-1a17A:
undetectable
4qvnW-1a17A:
undetectable		 4qvnV-1a17A:
21.85
4qvnW-1a17A:
23.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVP_H_BO2H301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 1a17 SERINE/THREONINE
PROTEIN PHOSPHATASE
5
(Homo
sapiens) 		5 / 12 SER A 105
GLY A  83
THR A  86
ALA A  85
ASP A 118
 None
 1.22A 4qvpH-1a17A:
undetectable
4qvpI-1a17A:
undetectable		 4qvpH-1a17A:
21.85
4qvpI-1a17A:
23.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVP_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 1a17 SERINE/THREONINE
PROTEIN PHOSPHATASE
5
(Homo
sapiens) 		5 / 12 SER A 105
GLY A  83
THR A  86
ALA A  85
ASP A 118
 None
 1.21A 4qvpV-1a17A:
undetectable
4qvpW-1a17A:
undetectable		 4qvpV-1a17A:
21.85
4qvpW-1a17A:
23.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVQ_H_BO2H301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 1a17 SERINE/THREONINE
PROTEIN PHOSPHATASE
5
(Homo
sapiens) 		5 / 11 SER A 105
GLY A  83
THR A  86
ALA A  85
ASP A 118
 None
 1.23A 4qvqH-1a17A:
undetectable
4qvqI-1a17A:
undetectable		 4qvqH-1a17A:
21.85
4qvqI-1a17A:
23.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVQ_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 1a17 SERINE/THREONINE
PROTEIN PHOSPHATASE
5
(Homo
sapiens) 		5 / 11 SER A 105
GLY A  83
THR A  86
ALA A  85
ASP A 118
 None
 1.22A 4qvqV-1a17A:
undetectable
4qvqW-1a17A:
undetectable		 4qvqV-1a17A:
21.85
4qvqW-1a17A:
23.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW1_H_BO2H301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 1a17 SERINE/THREONINE
PROTEIN PHOSPHATASE
5
(Homo
sapiens) 		5 / 12 SER A 105
GLY A  83
THR A  86
ALA A  85
ASP A 118
 None
 1.25A 4qw1H-1a17A:
undetectable
4qw1I-1a17A:
undetectable		 4qw1H-1a17A:
21.85
4qw1I-1a17A:
23.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW1_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 1a17 SERINE/THREONINE
PROTEIN PHOSPHATASE
5
(Homo
sapiens) 		5 / 12 SER A 105
GLY A  83
THR A  86
ALA A  85
ASP A 118
 None
 1.24A 4qw1V-1a17A:
undetectable
4qw1W-1a17A:
undetectable		 4qw1V-1a17A:
21.85
4qw1W-1a17A:
23.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L66_H_BO2H301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 1a17 SERINE/THREONINE
PROTEIN PHOSPHATASE
5
(Homo
sapiens) 		5 / 12 SER A 105
GLY A  83
THR A  86
ALA A  85
ASP A 118
 None
 1.21A 5l66H-1a17A:
undetectable
5l66I-1a17A:
undetectable		 5l66H-1a17A:
21.85
5l66I-1a17A:
23.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L66_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 1a17 SERINE/THREONINE
PROTEIN PHOSPHATASE
5
(Homo
sapiens) 		5 / 12 SER A 105
GLY A  83
THR A  86
ALA A  85
ASP A 118
 None
 1.20A 5l66V-1a17A:
undetectable
5l66W-1a17A:
undetectable		 5l66V-1a17A:
21.85
5l66W-1a17A:
23.61