SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1a2a'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1SV9_A_DIFA701_1
(PHOSPHOLIPASE A2)		 1a2a PHOSPHOLIPASE A2
(Gloydius
halys) 		8 / 8 LEU A   2
ALA A  18
ILE A  19
CYH A  29
GLY A  30
CYH A  45
HIS A  48
PHE A 106
 None
 0.54A 1sv9A-1a2aA:
22.6		 1sv9A-1a2aA:
62.30
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1TD7_A_NFLA2001_1
(PHOSPHOLIPASE A2
ISOFORM 3)		 1a2a PHOSPHOLIPASE A2
(Gloydius
halys) 		5 / 9 LEU A   2
ILE A   9
GLY A  30
CYH A  45
PHE A 106
 None
 0.52A 1td7A-1a2aA:
18.8		 1td7A-1a2aA:
41.27
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1TH6_A_OINA401_1
(PHOSPHOLIPASE A2)		 1a2a PHOSPHOLIPASE A2
(Gloydius
halys) 		4 / 7 GLY A  30
HIS A  48
ASP A  49
TYR A  52
 None
 0.26A 1th6A-1a2aA:
22.5		 1th6A-1a2aA:
62.30
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1TH6_A_OINA401_1
(PHOSPHOLIPASE A2)		 1a2a PHOSPHOLIPASE A2
(Gloydius
halys) 		4 / 7 GLY A  31
HIS A  48
ASP A  49
TYR A  52
 None
 0.86A 1th6A-1a2aA:
22.5		 1th6A-1a2aA:
62.30
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2ARM_A_OINA401_1
(PHOSPHOLIPASE A2
VRV-PL-VIIIA)		 1a2a PHOSPHOLIPASE A2
(Gloydius
halys) 		4 / 7 GLY A  30
HIS A  48
ASP A  49
TYR A  52
 None
 0.27A 2armA-1a2aA:
22.5		 2armA-1a2aA:
62.30
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2ARM_A_OINA401_1
(PHOSPHOLIPASE A2
VRV-PL-VIIIA)		 1a2a PHOSPHOLIPASE A2
(Gloydius
halys) 		4 / 7 GLY A  31
HIS A  48
ASP A  49
TYR A  52
 None
 0.89A 2armA-1a2aA:
22.5		 2armA-1a2aA:
62.30
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2B17_A_DIFA701_1
(PHOSPHOLIPASE A2
VRV-PL-VIIIA)		 1a2a PHOSPHOLIPASE A2
(Gloydius
halys) 		9 / 10 LEU A   2
ALA A  18
ILE A  19
CYH A  29
GLY A  30
CYH A  45
HIS A  48
ASP A  49
PHE A 106
 None
 0.54A 2b17A-1a2aA:
22.5		 2b17A-1a2aA:
62.30
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2DPZ_A_TYLA2001_1
(PHOSPHOLIPASE A2
VRV-PL-VIIIA)		 1a2a PHOSPHOLIPASE A2
(Gloydius
halys) 		5 / 6 LEU A   2
ALA A  18
HIS A  48
ASP A  49
TYR A  52
 None
 0.52A 2dpzA-1a2aA:
22.3		 2dpzA-1a2aA:
62.30
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2OTF_A_2TNA201_1
(PHOSPHOLIPASE A2
VRV-PL-VIIIA)		 1a2a PHOSPHOLIPASE A2
(Gloydius
halys) 		4 / 5 LEU A   2
ILE A  19
GLY A  30
HIS A  48
 None
 0.80A 2otfA-1a2aA:
22.3		 2otfA-1a2aA:
62.30
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3BJW_E_SVRE510_2
(PHOSPHOLIPASE A2)		 1a2a PHOSPHOLIPASE A2
(Gloydius
halys) 		4 / 6 LYS A   7
GLY A  15
ARG A 107
LEU A 110
 None
 0.90A 3bjwE-1a2aA:
21.6		 3bjwE-1a2aA:
46.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CZH_A_D2VA602_2
(CYTOCHROME P450 2R1)		 1a2a PHOSPHOLIPASE A2
(Gloydius
halys) 		3 / 3 LEU A 110
GLU A  13
ILE A   9
 None
 0.55A 3czhA-1a2aA:
undetectable		 3czhA-1a2aA:
10.75
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3OSH_A_OINA5811_1
(PHOSPHOLIPASE A2
ISOFORM 3)		 1a2a PHOSPHOLIPASE A2
(Gloydius
halys) 		5 / 9 LEU A   2
PHE A   5
ILE A   9
GLY A  30
HIS A  48
 None
 0.36A 3oshA-1a2aA:
19.1		 3oshA-1a2aA:
40.48
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3R0L_D_ACTD127_0
(PHOSPHOLIPASE A2 CB)		 1a2a PHOSPHOLIPASE A2
(Gloydius
halys) 		5 / 5 PHE A   5
ILE A   9
GLY A  30
CYH A  45
HIS A  48
 None
 0.56A 3r0lD-1a2aA:
24.0		 3r0lD-1a2aA:
79.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LSU_B_SAMB1304_1
(HISTONE-LYSINE
N-METHYLTRANSFERASE
NSD2)		 1a2a PHOSPHOLIPASE A2
(Gloydius
halys) 		3 / 3 ASN A  34
TYR A  28
CYH A 126
 None
 1.02A 5lsuB-1a2aA:
undetectable		 5lsuB-1a2aA:
19.44