SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1a33'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)	View	Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2M2P_B_DHIB24_0 (INSULIN B CHAIN)	1a33	PEPTIDYLPROLYL ISOMERASE (Brugia malayi)	3 / 3	TYR A 59 GLY A 61 PHE A 78	None	0.65A	2m2pB-1a33A: undetectable	2m2pB-1a33A: 11.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3FPJ_B_SAMB301_0 (PUTATIVE UNCHARACTERIZED PROTEIN)	1a33	PEPTIDYLPROLYL ISOMERASE (Brugia malayi)	5 / 12	PHE A 124 ILE A 125 VAL A 109 GLU A 105 VAL A 150	None	1.18A	3fpjB-1a33A: undetectable	3fpjB-1a33A: 21.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3V4T_H_ACTH502_0 (UDP-N-ACETYLGLUCOSAM INE 1-CARBOXYVINYLTRANSF ERASE)	1a33	PEPTIDYLPROLYL ISOMERASE (Brugia malayi)	3 / 3	SER A 145 GLY A 146 GLN A 147	None	0.53A	3v4tH-1a33A: 0.0	3v4tH-1a33A: 18.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5ALC_L_TIQL1210_2 (ANTI-TICAGRELOR FAB 72, LIGHT CHAIN)	1a33	PEPTIDYLPROLYL ISOMERASE (Brugia malayi)	4 / 8	SER A 145 GLY A 146 ILE A 170 GLY A 21	None	0.81A	5alcL-1a33A: undetectable	5alcL-1a33A: 19.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5H5F_A_SAMA301_0 (PROTEIN ARGININE N-METHYLTRANSFERASE SFM1)	1a33	PEPTIDYLPROLYL ISOMERASE (Brugia malayi)	5 / 12	PHE A 64 ILE A 15 GLY A 17 ARG A 22 LEU A 11	None	1.12A	5h5fA-1a33A: undetectable	5h5fA-1a33A: 17.80

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["2M2P_B_DHIB24_0","INSULIN B CHAIN","1a33","PEPTIDYLPROLYL ISOMERASE","Brugia malayi",3,"TYR A  59;GLY A  61;PHE A  78","None","0.65A","2m2pB-1a33A:undetectable","2m2pB-1a33A:11.41"],["3FPJ_B_SAMB301_0","PUTATIVE UNCHARACTERIZED PROTEIN","1a33","PEPTIDYLPROLYL ISOMERASE","Brugia malayi",5,"PHE A 124;ILE A 125;VAL A 109;GLU A 105;VAL A 150","None","1.18A","3fpjB-1a33A:undetectable","3fpjB-1a33A:21.02"],["3V4T_H_ACTH502_0","UDP-N-ACETYLGLUCOSAMINE 1-CARBOXYVINYLTRANSFERASE","1a33","PEPTIDYLPROLYL ISOMERASE","Brugia malayi",3,"SER A 145;GLY A 146;GLN A 147","None","0.53A","3v4tH-1a33A:0.0","3v4tH-1a33A:18.16"],["5ALC_L_TIQL1210_2","ANTI-TICAGRELOR FAB 72, LIGHT CHAIN","1a33","PEPTIDYLPROLYL ISOMERASE","Brugia malayi",4,"SER A 145;GLY A 146;ILE A 170;GLY A  21","None","0.81A","5alcL-1a33A:undetectable","5alcL-1a33A:19.72"],["5H5F_A_SAMA301_0","PROTEIN ARGININE N-METHYLTRANSFERASE SFM1","1a33","PEPTIDYLPROLYL ISOMERASE","Brugia malayi",5,"PHE A  64;ILE A  15;GLY A  17;ARG A  22;LEU A  11","None","1.12A","5h5fA-1a33A:undetectable","5h5fA-1a33A:17.80"]]