SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1a3q'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OQ5_A_CELA701_2
(CARBONIC ANHYDRASE
II)		 1a3q PROTEIN (NUCLEAR
FACTOR KAPPA-B P52)
(Homo
sapiens) 		4 / 4 HIS A 107
VAL A 138
THR A 149
LEU A 117
 None
 1.45A 1oq5A-1a3qA:
0.0		 1oq5A-1a3qA:
23.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V55_P_CHDP4271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE III
CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART)		 1a3q PROTEIN (NUCLEAR
FACTOR KAPPA-B P52)
(Homo
sapiens) 		4 / 7 LYS A 310
LEU A 309
LEU A 248
PHE A 289
 None
 0.96A 1v55P-1a3qA:
undetectable
1v55W-1a3qA:
0.0		 1v55P-1a3qA:
21.92
1v55W-1a3qA:
13.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYS_C_CHDC310_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1a3q PROTEIN (NUCLEAR
FACTOR KAPPA-B P52)
(Homo
sapiens) 		4 / 7 LYS A 310
LEU A 309
LEU A 248
PHE A 289
 None
 0.98A 2dysC-1a3qA:
undetectable
2dysJ-1a3qA:
0.0		 2dysC-1a3qA:
21.92
2dysJ-1a3qA:
13.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIJ_P_CHDP1271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1a3q PROTEIN (NUCLEAR
FACTOR KAPPA-B P52)
(Homo
sapiens) 		4 / 7 LYS A 310
LEU A 309
LEU A 248
PHE A 289
 None
 1.00A 2eijP-1a3qA:
undetectable
2eijW-1a3qA:
undetectable		 2eijP-1a3qA:
21.92
2eijW-1a3qA:
13.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIN_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1a3q PROTEIN (NUCLEAR
FACTOR KAPPA-B P52)
(Homo
sapiens) 		4 / 7 LYS A 310
LEU A 309
LEU A 248
PHE A 289
 None
 1.00A 2einC-1a3qA:
undetectable
2einJ-1a3qA:
0.0		 2einC-1a3qA:
21.92
2einJ-1a3qA:
13.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OXT_C_SAMC300_1
(NUCLEOSIDE-2'-O-METH
YLTRANSFERASE)		 1a3q PROTEIN (NUCLEAR
FACTOR KAPPA-B P52)
(Homo
sapiens) 		4 / 4 SER A 220
GLY A  50
HIS A 105
ASP A  94
 None
 1.31A 2oxtC-1a3qA:
undetectable		 2oxtC-1a3qA:
20.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q72_A_IXXA802_1
(TRANSPORTER)		 1a3q PROTEIN (NUCLEAR
FACTOR KAPPA-B P52)
(Homo
sapiens) 		4 / 6 ILE A 230
SER A 318
ARG A 261
PHE A 289
 None
 0.79A 2q72A-1a3qA:
2.8		 2q72A-1a3qA:
19.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QB4_A_DSMA802_1
(TRANSPORTER)		 1a3q PROTEIN (NUCLEAR
FACTOR KAPPA-B P52)
(Homo
sapiens) 		4 / 7 ILE A 230
SER A 318
ARG A 261
PHE A 289
 None
 0.82A 2qb4A-1a3qA:
2.0		 2qb4A-1a3qA:
19.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZXW_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1a3q PROTEIN (NUCLEAR
FACTOR KAPPA-B P52)
(Homo
sapiens) 		4 / 7 LYS A 310
LEU A 309
LEU A 248
PHE A 289
 None
 0.89A 2zxwC-1a3qA:
undetectable
2zxwJ-1a3qA:
0.0		 2zxwC-1a3qA:
21.92
2zxwJ-1a3qA:
13.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASN_P_CHDP1271_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1)		 1a3q PROTEIN (NUCLEAR
FACTOR KAPPA-B P52)
(Homo
sapiens) 		4 / 7 LYS A 310
LEU A 309
LEU A 248
PHE A 289
 None
 0.99A 3asnP-1a3qA:
undetectable
3asnW-1a3qA:
undetectable		 3asnP-1a3qA:
21.92
3asnW-1a3qA:
13.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASO_C_CHDC271_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1)		 1a3q PROTEIN (NUCLEAR
FACTOR KAPPA-B P52)
(Homo
sapiens) 		4 / 8 LYS A 310
LEU A 309
LEU A 248
PHE A 289
 None
 0.96A 3asoC-1a3qA:
undetectable
3asoJ-1a3qA:
0.0		 3asoC-1a3qA:
21.92
3asoJ-1a3qA:
13.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MS9_B_STIB1_2
(TYROSINE-PROTEIN
KINASE ABL1)		 1a3q PROTEIN (NUCLEAR
FACTOR KAPPA-B P52)
(Homo
sapiens) 		4 / 7 TYR A  39
VAL A  43
ILE A  91
ARG A 191
 None
 1.14A 3ms9B-1a3qA:
undetectable		 3ms9B-1a3qA:
21.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QEL_D_QELD2_1
(NMDA GLUTAMATE
RECEPTOR SUBUNIT
GLUTAMATE [NMDA]
RECEPTOR SUBUNIT
EPSILON-2)		 1a3q PROTEIN (NUCLEAR
FACTOR KAPPA-B P52)
(Homo
sapiens) 		4 / 5 TYR A  77
THR A  79
PHE A 133
LEU A  65
 None
 1.31A 3qelC-1a3qA:
undetectable		 3qelC-1a3qA:
20.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UY4_A_PAUA302_0
(PANTOTHENATE
SYNTHETASE)		 1a3q PROTEIN (NUCLEAR
FACTOR KAPPA-B P52)
(Homo
sapiens) 		4 / 8 HIS A 107
VAL A 138
VAL A 110
ASP A 219
 None
 1.14A 3uy4A-1a3qA:
2.2		 3uy4A-1a3qA:
22.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X20_D_LOCD502_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		 1a3q PROTEIN (NUCLEAR
FACTOR KAPPA-B P52)
(Homo
sapiens) 		3 / 3 SER A 115
ALA A 121
VAL A 122
 None
 0.57A 4x20C-1a3qA:
undetectable		 4x20C-1a3qA:
20.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5W97_C_CHDC306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 1a3q PROTEIN (NUCLEAR
FACTOR KAPPA-B P52)
(Homo
sapiens) 		4 / 6 LYS A 310
LEU A 309
LEU A 248
PHE A 289
 None
 1.01A 5w97C-1a3qA:
undetectable
5w97J-1a3qA:
0.0		 5w97C-1a3qA:
21.92
5w97J-1a3qA:
13.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HZP_A_FVTA501_0
(PEPTIDE ABC
TRANSPORTER PERMEASE)		 1a3q PROTEIN (NUCLEAR
FACTOR KAPPA-B P52)
(Homo
sapiens) 		4 / 8 VAL A  96
GLN A  45
PRO A 216
ILE A 217
 None
 0.92A 6hzpA-1a3qA:
undetectable		 6hzpA-1a3qA:
18.47