SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1a41'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2MJI_A_KTRA201_1
(FATTY ACID-BINDING
PROTEIN, INTESTINAL)		 1a41 TOPOISOMERASE I
(Vaccinia
virus) 		5 / 12 MET A 275
ILE A 303
THR A 278
PHE A  88
TYR A 229
 None
 1.19A 2mjiA-1a41A:
0.0		 2mjiA-1a41A:
20.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QEB_A_HSMA145_1
(D7R4 PROTEIN)		 1a41 TOPOISOMERASE I
(Vaccinia
virus) 		4 / 7 ILE A 279
TYR A 274
PHE A  88
ASP A  85
 None
 0.90A 2qebA-1a41A:
undetectable		 2qebA-1a41A:
21.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QEB_B_HSMB145_1
(D7R4 PROTEIN)		 1a41 TOPOISOMERASE I
(Vaccinia
virus) 		4 / 7 ILE A 279
TYR A 274
PHE A  88
ASP A  85
 None
 0.89A 2qebB-1a41A:
0.0		 2qebB-1a41A:
21.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F88_A_STRA502_1
(CYTOCHROME P450
CYP260A1)		 1a41 TOPOISOMERASE I
(Vaccinia
virus) 		4 / 6 PHE A 288
LEU A 289
SER A 247
THR A 255
 None
 0.88A 6f88A-1a41A:
1.2		 6f88A-1a41A:
15.87