SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1a44'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IG3_A_VIBA502_1
(THIAMIN
PYROPHOSPHOKINASE)		 1a44 PHOSPHATIDYLETHANOLA
MINE-BINDING PROTEIN
(Bos
taurus) 		4 / 8 LEU A  67
SER A 108
ASP A  71
THR A 114
 None
 1.03A 1ig3A-1a44A:
0.0
1ig3B-1a44A:
0.0		 1ig3A-1a44A:
19.40
1ig3B-1a44A:
19.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HZN_G_ACTG225_0
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)		 1a44 PHOSPHATIDYLETHANOLA
MINE-BINDING PROTEIN
(Bos
taurus) 		3 / 3 PRO A 129
LEU A 130
GLN A 126
 None
 0.54A 3hznG-1a44A:
0.0
3hznH-1a44A:
0.0		 3hznG-1a44A:
20.61
3hznH-1a44A:
20.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M5M_A_DX4A401_0
(2-AMINO-4-HYDROXY-6-
HYDROXYMETHYLDIHYDRO
PTERIDINE
PYROPHOSPHOKINASE)		 1a44 PHOSPHATIDYLETHANOLA
MINE-BINDING PROTEIN
(Bos
taurus) 		4 / 8 GLY A 146
THR A  68
LEU A  87
PHE A 148
 None
 1.20A 4m5mA-1a44A:
0.2		 4m5mA-1a44A:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PUO_C_NVPC901_1
(HIV-1 REVERSE
TRANSCRIPTASE, P66
SUBUNIT)		 1a44 PHOSPHATIDYLETHANOLA
MINE-BINDING PROTEIN
(Bos
taurus) 		4 / 8 VAL A 123
VAL A  88
TYR A  63
LEU A  57
 None
 1.02A 4puoC-1a44A:
undetectable		 4puoC-1a44A:
16.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TWD_C_377C401_1
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 1a44 PHOSPHATIDYLETHANOLA
MINE-BINDING PROTEIN
(Bos
taurus) 		4 / 6 ASN A  90
GLU A 134
TYR A 157
PHE A 153
 None
 0.91A 4twdB-1a44A:
0.0
4twdC-1a44A:
undetectable		 4twdB-1a44A:
18.97
4twdC-1a44A:
18.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TWD_E_377E401_1
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 1a44 PHOSPHATIDYLETHANOLA
MINE-BINDING PROTEIN
(Bos
taurus) 		4 / 6 ASN A  90
GLU A 134
TYR A 157
PHE A 153
 None
 0.95A 4twdD-1a44A:
undetectable
4twdE-1a44A:
0.0		 4twdD-1a44A:
18.97
4twdE-1a44A:
18.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TWD_G_377G401_1
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 1a44 PHOSPHATIDYLETHANOLA
MINE-BINDING PROTEIN
(Bos
taurus) 		4 / 6 GLU A 134
TYR A 157
LEU A 159
PHE A 153
 None
 1.39A 4twdF-1a44A:
0.0
4twdG-1a44A:
undetectable		 4twdF-1a44A:
18.97
4twdG-1a44A:
18.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5PHH_A_LDPA414_1
(LYSINE-SPECIFIC
DEMETHYLASE 4D)		 1a44 PHOSPHATIDYLETHANOLA
MINE-BINDING PROTEIN
(Bos
taurus) 		4 / 6 ALA A 170
LEU A  40
TYR A  28
SER A 108
 None
 0.95A 5phhA-1a44A:
0.0		 5phhA-1a44A:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EKU_A_ZMRA901_2
(SIALIDASE)		 1a44 PHOSPHATIDYLETHANOLA
MINE-BINDING PROTEIN
(Bos
taurus) 		4 / 6 ASP A 133
LEU A  87
SER A 103
PHE A 148
 None
 1.15A 6ekuA-1a44A:
0.0		 6ekuA-1a44A:
12.57