SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1a4k'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JX1_B_CAMB502_0
(CAMPHOR
5-MONOOXYGENASE)		 1a4k ANTIBODY FAB
(Mus
musculus) 		5 / 10 PHE H 122
GLY H 118
THR H 205
VAL H 198
VAL H 207
 None
 1.21A 4jx1B-1a4kH:
undetectable		 4jx1B-1a4kH:
18.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XDT_A_ACTA409_0
(FAD:PROTEIN FMN
TRANSFERASE)		 1a4k ANTIBODY FAB
(Mus
musculus) 		4 / 5 VAL H  18
ILE H  20
VAL H 109
THR H 107
 None
 0.73A 4xdtA-1a4kH:
0.6		 4xdtA-1a4kH:
20.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ECM_D_LEUD602_0
(JASMONIC ACID-AMIDO
SYNTHETASE JAR1)		 1a4k ANTIBODY FAB
(Mus
musculus) 		4 / 7 ALA H  88
THR H  87
VAL H 109
GLU H  85
 None
 0.76A 5ecmD-1a4kH:
0.0		 5ecmD-1a4kH:
17.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ECN_D_LEUD602_0
(JASMONIC ACID-AMIDO
SYNTHETASE JAR1)		 1a4k ANTIBODY FAB
(Mus
musculus) 		4 / 8 ALA H  88
THR H  87
VAL H 109
GLU H  85
 None
 0.75A 5ecnD-1a4kH:
undetectable		 5ecnD-1a4kH:
17.43