SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1a5f'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DSD_C_DVAC2_0
(ACTINOMYCIN D)		 1a5f MONOCLONAL
ANTI-E-SELECTIN 7A9
ANTIBODY (HEAVY
CHAIN)
(Mus
musculus) 		4 / 4 THR H 124
PRO H 154
THR H 123
PRO H 125
 None
 1.35A 1dsdC-1a5fH:
undetectable		 1dsdC-1a5fH:
13.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DSD_C_DVAC8_0
(ACTINOMYCIN D)		 1a5f MONOCLONAL
ANTI-E-SELECTIN 7A9
ANTIBODY (HEAVY
CHAIN)
(Mus
musculus) 		4 / 4 THR H 124
PRO H 154
THR H 123
PRO H 125
 None
 1.35A 1dsdC-1a5fH:
undetectable		 1dsdC-1a5fH:
13.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y03_A_5FWA601_1
(BETA-1 ADRENERGIC
RECEPTOR)		 1a5f MONOCLONAL
ANTI-E-SELECTIN 7A9
ANTIBODY (HEAVY
CHAIN)
(Mus
musculus) 		5 / 12 VAL H 170
VAL H 188
SER H 186
ASN H 200
ASN H 162
 None
 1.45A 2y03A-1a5fH:
undetectable		 2y03A-1a5fH:
21.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y03_B_5FWB601_1
(BETA-1 ADRENERGIC
RECEPTOR)		 1a5f MONOCLONAL
ANTI-E-SELECTIN 7A9
ANTIBODY (HEAVY
CHAIN)
(Mus
musculus) 		5 / 12 VAL H 170
VAL H 188
SER H 186
ASN H 200
ASN H 162
 None
 1.48A 2y03B-1a5fH:
undetectable		 2y03B-1a5fH:
21.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LN1_A_CELA682_2
(PROSTAGLANDIN G/H
SYNTHASE 2)		 1a5f MONOCLONAL
ANTI-E-SELECTIN 7A9
ANTIBODY (HEAVY
CHAIN)
(Mus
musculus) 		4 / 8 LEU H  86
SER H  85
LEU H  81
TYR H  94
 None
 0.88A 3ln1A-1a5fH:
0.0		 3ln1A-1a5fH:
15.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NYA_A_JTZA1203_1
(BETA-2 ADRENERGIC
RECEPTOR, LYSOZYME)		 1a5f MONOCLONAL
ANTI-E-SELECTIN 7A9
ANTIBODY (HEAVY
CHAIN)
(Mus
musculus) 		5 / 12 VAL H 170
VAL H 188
SER H 186
ASN H 200
ASN H 162
 None
 1.40A 3nyaA-1a5fH:
undetectable		 3nyaA-1a5fH:
17.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IKJ_B_SUZB201_1
(TRANSTHYRETIN)		 1a5f MONOCLONAL
ANTI-E-SELECTIN 7A9
ANTIBODY (HEAVY
CHAIN)
(Mus
musculus) 		4 / 8 SER H   7
SER H  21
LYS H  38
THR H 114
 None
 1.00A 4ikjA-1a5fH:
0.3
4ikjB-1a5fH:
0.4		 4ikjA-1a5fH:
21.33
4ikjB-1a5fH:
21.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IKL_B_SUZB201_1
(TRANSTHYRETIN)		 1a5f MONOCLONAL
ANTI-E-SELECTIN 7A9
ANTIBODY (HEAVY
CHAIN)
(Mus
musculus) 		4 / 8 SER H   7
SER H  21
LYS H  38
THR H 114
 None
 1.00A 4iklA-1a5fH:
undetectable
4iklB-1a5fH:
undetectable		 4iklA-1a5fH:
21.33
4iklB-1a5fH:
21.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LDO_A_ALEA1402_1
(LYSOZYME, BETA-2
ADRENERGIC RECEPTOR)		 1a5f MONOCLONAL
ANTI-E-SELECTIN 7A9
ANTIBODY (HEAVY
CHAIN)
(Mus
musculus) 		5 / 10 VAL H 170
VAL H 188
SER H 186
ASN H 200
ASN H 162
 None
 1.48A 4ldoA-1a5fH:
undetectable		 4ldoA-1a5fH:
18.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Y0Q_A_PX9A201_0
(BETA-LACTOGLOBULIN)		 1a5f MONOCLONAL
ANTI-E-SELECTIN 7A9
ANTIBODY (HEAVY
CHAIN)
(Mus
musculus) 		5 / 12 LEU H 166
VAL H 188
ILE H 214
LEU H 145
VAL H 210
 None
 0.98A 4y0qA-1a5fH:
undetectable		 4y0qA-1a5fH:
22.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L94_A_TESA502_1
(CYTOCHROME P450)		 1a5f MONOCLONAL
ANTI-E-SELECTIN 7A9
ANTIBODY (HEAVY
CHAIN)
(Mus
musculus) 		5 / 8 VAL H 197
ILE H 214
ALA H 132
VAL H 143
VAL H 190
 None
 1.43A 5l94A-1a5fH:
0.0		 5l94A-1a5fH:
18.47