SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1a6c'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WRL_D_TFPD207_1
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)
1a6c TOBACCO RINGSPOT
VIRUS CAPSID PROTEIN

(Tobacco
ringspot
virus)
4 / 8 PHE A  31
PHE A  78
LEU A 128
MET A 162
None
0.99A 1wrlC-1a6cA:
undetectable
1wrlD-1a6cA:
undetectable
1wrlC-1a6cA:
12.56
1wrlD-1a6cA:
12.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WRL_E_TFPE212_1
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)
1a6c TOBACCO RINGSPOT
VIRUS CAPSID PROTEIN

(Tobacco
ringspot
virus)
4 / 7 PHE A  31
PHE A  78
LEU A 128
MET A 162
None
1.10A 1wrlE-1a6cA:
undetectable
1wrlE-1a6cA:
12.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XWF_A_ADNA433_2
(ADENOSYLHOMOCYSTEINA
SE)
1a6c TOBACCO RINGSPOT
VIRUS CAPSID PROTEIN

(Tobacco
ringspot
virus)
3 / 3 THR A 178
GLU A 174
HIS A 407
None
0.88A 1xwfA-1a6cA:
0.0
1xwfA-1a6cA:
22.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XWF_B_ADNB433_2
(ADENOSYLHOMOCYSTEINA
SE)
1a6c TOBACCO RINGSPOT
VIRUS CAPSID PROTEIN

(Tobacco
ringspot
virus)
3 / 3 THR A 178
GLU A 174
HIS A 407
None
0.89A 1xwfB-1a6cA:
0.0
1xwfB-1a6cA:
22.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XWF_C_ADNC433_2
(ADENOSYLHOMOCYSTEINA
SE)
1a6c TOBACCO RINGSPOT
VIRUS CAPSID PROTEIN

(Tobacco
ringspot
virus)
3 / 3 THR A 178
GLU A 174
HIS A 407
None
0.88A 1xwfC-1a6cA:
0.0
1xwfC-1a6cA:
22.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XWF_D_ADND433_2
(ADENOSYLHOMOCYSTEINA
SE)
1a6c TOBACCO RINGSPOT
VIRUS CAPSID PROTEIN

(Tobacco
ringspot
virus)
3 / 3 THR A 178
GLU A 174
HIS A 407
None
0.91A 1xwfD-1a6cA:
0.0
1xwfD-1a6cA:
22.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZZR_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)
1a6c TOBACCO RINGSPOT
VIRUS CAPSID PROTEIN

(Tobacco
ringspot
virus)
4 / 7 VAL A 496
ARG A 482
VAL A 390
PHE A 374
None
1.24A 1zzrA-1a6cA:
0.0
1zzrB-1a6cA:
0.0
1zzrA-1a6cA:
19.96
1zzrB-1a6cA:
19.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZZR_B_H4BB761_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)
1a6c TOBACCO RINGSPOT
VIRUS CAPSID PROTEIN

(Tobacco
ringspot
virus)
4 / 7 PHE A 374
VAL A 496
ARG A 482
VAL A 390
None
1.26A 1zzrA-1a6cA:
0.0
1zzrB-1a6cA:
0.0
1zzrA-1a6cA:
19.96
1zzrB-1a6cA:
19.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZZU_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)
1a6c TOBACCO RINGSPOT
VIRUS CAPSID PROTEIN

(Tobacco
ringspot
virus)
4 / 7 VAL A 496
ARG A 482
VAL A 390
PHE A 374
None
1.23A 1zzuA-1a6cA:
0.0
1zzuB-1a6cA:
0.0
1zzuA-1a6cA:
19.96
1zzuB-1a6cA:
19.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZZU_B_H4BB761_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)
1a6c TOBACCO RINGSPOT
VIRUS CAPSID PROTEIN

(Tobacco
ringspot
virus)
4 / 7 PHE A 374
VAL A 496
ARG A 482
VAL A 390
None
1.26A 1zzuA-1a6cA:
0.0
1zzuB-1a6cA:
0.0
1zzuA-1a6cA:
19.96
1zzuB-1a6cA:
19.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2LH6_A_NIOA155_1
(LEGHEMOGLOBIN A
(NICOTINATE MET))
1a6c TOBACCO RINGSPOT
VIRUS CAPSID PROTEIN

(Tobacco
ringspot
virus)
4 / 5 PHE A  16
PHE A 106
HIS A 114
VAL A 160
None
1.21A 2lh6A-1a6cA:
undetectable
2lh6A-1a6cA:
13.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OTH_A_NIMA300_1
(PHOSPHOLIPASE A2
VRV-PL-VIIIA)
1a6c TOBACCO RINGSPOT
VIRUS CAPSID PROTEIN

(Tobacco
ringspot
virus)
4 / 5 LEU A 185
ALA A 190
ILE A 191
SER A 230
None
1.09A 2othA-1a6cA:
0.0
2othA-1a6cA:
12.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VQY_A_PARA1201_2
(AAC(6')-IB)
1a6c TOBACCO RINGSPOT
VIRUS CAPSID PROTEIN

(Tobacco
ringspot
virus)
3 / 3 TRP A 181
GLN A 184
TRP A 506
None
1.23A 2vqyA-1a6cA:
0.0
2vqyA-1a6cA:
18.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XKW_B_P1BB1475_2
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)
1a6c TOBACCO RINGSPOT
VIRUS CAPSID PROTEIN

(Tobacco
ringspot
virus)
4 / 6 LEU A 128
ARG A  34
ILE A  37
ILE A 159
None
0.93A 2xkwB-1a6cA:
undetectable
2xkwB-1a6cA:
17.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y00_B_Y00B601_2
(BETA-1 ADRENERGIC
RECEPTOR)
1a6c TOBACCO RINGSPOT
VIRUS CAPSID PROTEIN

(Tobacco
ringspot
virus)
3 / 3 VAL A 430
ASN A 373
TRP A 439
None
1.11A 2y00B-1a6cA:
undetectable
2y00B-1a6cA:
20.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BRF_A_SORA2_0
(LIN-12 AND GLP-1
PHENOTYPE PROTEIN 1,
ISOFORM A)
1a6c TOBACCO RINGSPOT
VIRUS CAPSID PROTEIN

(Tobacco
ringspot
virus)
3 / 3 LYS A 249
LYS A 104
VAL A 105
None
1.08A 3brfA-1a6cA:
0.0
3brfA-1a6cA:
20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DQR_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
1a6c TOBACCO RINGSPOT
VIRUS CAPSID PROTEIN

(Tobacco
ringspot
virus)
4 / 7 VAL A 496
ARG A 482
VAL A 390
PHE A 374
None
1.18A 3dqrA-1a6cA:
0.0
3dqrB-1a6cA:
0.0
3dqrA-1a6cA:
20.38
3dqrB-1a6cA:
20.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DQR_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
1a6c TOBACCO RINGSPOT
VIRUS CAPSID PROTEIN

(Tobacco
ringspot
virus)
4 / 7 PHE A 374
VAL A 496
ARG A 482
VAL A 390
None
1.26A 3dqrA-1a6cA:
0.0
3dqrB-1a6cA:
0.0
3dqrA-1a6cA:
20.38
3dqrB-1a6cA:
20.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JX2_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
1a6c TOBACCO RINGSPOT
VIRUS CAPSID PROTEIN

(Tobacco
ringspot
virus)
4 / 7 VAL A 496
ARG A 482
VAL A 390
PHE A 374
None
1.25A 3jx2A-1a6cA:
0.0
3jx2B-1a6cA:
0.0
3jx2A-1a6cA:
20.38
3jx2B-1a6cA:
20.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JX4_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
1a6c TOBACCO RINGSPOT
VIRUS CAPSID PROTEIN

(Tobacco
ringspot
virus)
4 / 6 VAL A 496
ARG A 482
VAL A 390
PHE A 374
None
1.21A 3jx4A-1a6cA:
0.0
3jx4B-1a6cA:
0.0
3jx4A-1a6cA:
20.38
3jx4B-1a6cA:
20.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JX4_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
1a6c TOBACCO RINGSPOT
VIRUS CAPSID PROTEIN

(Tobacco
ringspot
virus)
4 / 7 PHE A 374
VAL A 496
ARG A 482
VAL A 390
None
1.29A 3jx4A-1a6cA:
0.0
3jx4B-1a6cA:
0.0
3jx4A-1a6cA:
20.38
3jx4B-1a6cA:
20.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JX5_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
1a6c TOBACCO RINGSPOT
VIRUS CAPSID PROTEIN

(Tobacco
ringspot
virus)
4 / 7 VAL A 496
ARG A 482
VAL A 390
PHE A 374
None
1.25A 3jx5A-1a6cA:
0.0
3jx5B-1a6cA:
0.0
3jx5A-1a6cA:
20.38
3jx5B-1a6cA:
20.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JX5_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
1a6c TOBACCO RINGSPOT
VIRUS CAPSID PROTEIN

(Tobacco
ringspot
virus)
4 / 7 PHE A 374
VAL A 496
ARG A 482
VAL A 390
None
1.29A 3jx5A-1a6cA:
0.0
3jx5B-1a6cA:
0.0
3jx5A-1a6cA:
20.38
3jx5B-1a6cA:
20.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLJ_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
1a6c TOBACCO RINGSPOT
VIRUS CAPSID PROTEIN

(Tobacco
ringspot
virus)
4 / 7 VAL A 496
ARG A 482
VAL A 390
PHE A 374
None
1.24A 3nljA-1a6cA:
0.0
3nljB-1a6cA:
0.0
3nljA-1a6cA:
20.38
3nljB-1a6cA:
20.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLP_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
1a6c TOBACCO RINGSPOT
VIRUS CAPSID PROTEIN

(Tobacco
ringspot
virus)
4 / 7 VAL A 496
ARG A 482
VAL A 390
PHE A 374
None
1.26A 3nlpA-1a6cA:
0.0
3nlpB-1a6cA:
0.0
3nlpA-1a6cA:
20.38
3nlpB-1a6cA:
20.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLR_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
1a6c TOBACCO RINGSPOT
VIRUS CAPSID PROTEIN

(Tobacco
ringspot
virus)
4 / 7 VAL A 496
ARG A 482
VAL A 390
PHE A 374
None
1.26A 3nlrA-1a6cA:
0.0
3nlrB-1a6cA:
0.0
3nlrA-1a6cA:
20.38
3nlrB-1a6cA:
20.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OF4_B_ACTB313_0
(NITROREDUCTASE)
1a6c TOBACCO RINGSPOT
VIRUS CAPSID PROTEIN

(Tobacco
ringspot
virus)
3 / 3 ALA A 145
VAL A 144
GLN A 149
None
0.69A 3of4B-1a6cA:
undetectable
3of4B-1a6cA:
18.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C49_C_HCYC1384_1
(CORTICOSTEROID-BINDI
NG GLOBULIN)
1a6c TOBACCO RINGSPOT
VIRUS CAPSID PROTEIN

(Tobacco
ringspot
virus)
5 / 12 SER A  45
THR A  59
ILE A  33
PHE A  58
HIS A 163
None
1.32A 4c49C-1a6cA:
0.0
4c49C-1a6cA:
20.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C49_D_HCYD1384_1
(CORTICOSTEROID-BINDI
NG GLOBULIN)
1a6c TOBACCO RINGSPOT
VIRUS CAPSID PROTEIN

(Tobacco
ringspot
virus)
5 / 12 SER A  45
THR A  59
ILE A  33
PHE A  58
HIS A 163
None
1.38A 4c49D-1a6cA:
undetectable
4c49D-1a6cA:
20.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CX3_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
1a6c TOBACCO RINGSPOT
VIRUS CAPSID PROTEIN

(Tobacco
ringspot
virus)
4 / 7 VAL A 496
ARG A 482
VAL A 390
PHE A 374
None
1.24A 4cx3A-1a6cA:
0.0
4cx3B-1a6cA:
0.0
4cx3A-1a6cA:
20.38
4cx3B-1a6cA:
20.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CX4_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
1a6c TOBACCO RINGSPOT
VIRUS CAPSID PROTEIN

(Tobacco
ringspot
virus)
4 / 7 VAL A 496
ARG A 482
VAL A 390
PHE A 374
None
1.24A 4cx4A-1a6cA:
0.0
4cx4B-1a6cA:
0.0
4cx4A-1a6cA:
20.38
4cx4B-1a6cA:
20.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CX4_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
1a6c TOBACCO RINGSPOT
VIRUS CAPSID PROTEIN

(Tobacco
ringspot
virus)
4 / 7 PHE A 374
VAL A 496
ARG A 482
VAL A 390
None
1.30A 4cx4A-1a6cA:
0.0
4cx4B-1a6cA:
0.0
4cx4A-1a6cA:
20.38
4cx4B-1a6cA:
20.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4U14_A_0HKA2000_1
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M3,ENDOLYSIN,MUSCARI
NIC ACETYLCHOLINE
RECEPTOR M3)
1a6c TOBACCO RINGSPOT
VIRUS CAPSID PROTEIN

(Tobacco
ringspot
virus)
5 / 12 ILE A 170
THR A 470
ALA A 135
ASN A 133
CYH A 129
None
1.38A 4u14A-1a6cA:
undetectable
4u14A-1a6cA:
22.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ADD_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
1a6c TOBACCO RINGSPOT
VIRUS CAPSID PROTEIN

(Tobacco
ringspot
virus)
4 / 6 VAL A 496
ARG A 482
VAL A 390
PHE A 374
None
1.26A 5addA-1a6cA:
0.0
5addB-1a6cA:
0.0
5addA-1a6cA:
20.38
5addB-1a6cA:
20.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ADD_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
1a6c TOBACCO RINGSPOT
VIRUS CAPSID PROTEIN

(Tobacco
ringspot
virus)
4 / 7 PHE A 374
VAL A 496
ARG A 482
VAL A 390
None
1.29A 5addA-1a6cA:
undetectable
5addB-1a6cA:
0.0
5addA-1a6cA:
20.38
5addB-1a6cA:
20.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ADE_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
1a6c TOBACCO RINGSPOT
VIRUS CAPSID PROTEIN

(Tobacco
ringspot
virus)
4 / 6 VAL A 496
ARG A 482
VAL A 390
PHE A 374
None
1.31A 5adeA-1a6cA:
0.0
5adeB-1a6cA:
0.0
5adeA-1a6cA:
20.38
5adeB-1a6cA:
20.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BW4_A_SAMA301_0
(16S RRNA
(ADENINE(1408)-N(1))
-METHYLTRANSFERASE)
1a6c TOBACCO RINGSPOT
VIRUS CAPSID PROTEIN

(Tobacco
ringspot
virus)
5 / 12 GLY A 127
GLY A 121
THR A 178
PRO A  56
ILE A  53
None
1.19A 5bw4A-1a6cA:
undetectable
5bw4A-1a6cA:
21.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G0P_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
1a6c TOBACCO RINGSPOT
VIRUS CAPSID PROTEIN

(Tobacco
ringspot
virus)
4 / 7 VAL A 496
ARG A 482
VAL A 390
PHE A 374
None
1.24A 5g0pA-1a6cA:
0.0
5g0pB-1a6cA:
0.0
5g0pA-1a6cA:
20.38
5g0pB-1a6cA:
20.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G0P_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
1a6c TOBACCO RINGSPOT
VIRUS CAPSID PROTEIN

(Tobacco
ringspot
virus)
4 / 7 PHE A 374
VAL A 496
ARG A 482
VAL A 390
None
1.28A 5g0pA-1a6cA:
0.0
5g0pB-1a6cA:
0.0
5g0pA-1a6cA:
20.38
5g0pB-1a6cA:
20.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HWA_A_GCSA302_1
(CHITOSANASE)
1a6c TOBACCO RINGSPOT
VIRUS CAPSID PROTEIN

(Tobacco
ringspot
virus)
4 / 7 THR A 136
ASP A  80
TYR A 120
GLY A 125
None
1.12A 5hwaA-1a6cA:
0.0
5hwaA-1a6cA:
18.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HWA_A_GCSA302_1
(CHITOSANASE)
1a6c TOBACCO RINGSPOT
VIRUS CAPSID PROTEIN

(Tobacco
ringspot
virus)
4 / 7 THR A 136
ASP A  80
TYR A 120
GLY A 127
None
0.99A 5hwaA-1a6cA:
0.0
5hwaA-1a6cA:
18.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TDZ_A_ADNA905_1
(ATP-CITRATE SYNTHASE)
1a6c TOBACCO RINGSPOT
VIRUS CAPSID PROTEIN

(Tobacco
ringspot
virus)
4 / 6 THR A 139
ASP A  79
ARG A  83
ASP A  85
None
1.05A 5tdzA-1a6cA:
undetectable
5tdzA-1a6cA:
21.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UUN_A_ACTA305_0
(GLUTATHIONE
S-TRANSFERASE-LIKE
PROTEIN)
1a6c TOBACCO RINGSPOT
VIRUS CAPSID PROTEIN

(Tobacco
ringspot
virus)
3 / 3 THR A  13
MET A 162
HIS A 163
None
0.95A 5uunA-1a6cA:
undetectable
5uunA-1a6cA:
20.58