SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1a6g'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KYV_A_RBFA501_1
(6,7-DIMETHYL-8-RIBIT
YLLUMAZINE SYNTHASE)		 1a6g MYOGLOBIN
(Physeter
catodon) 		5 / 12 LEU A  86
ILE A 142
ILE A 107
LEU A 104
HIS A  97
 None
None
HEM  A 154 ( 3.9A)
None
HEM  A 154 (-3.4A)
 1.14A 1kyvA-1a6gA:
undetectable
1kyvE-1a6gA:
undetectable		 1kyvA-1a6gA:
25.27
1kyvE-1a6gA:
25.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KYV_C_RBFC503_1
(6,7-DIMETHYL-8-RIBIT
YLLUMAZINE SYNTHASE)		 1a6g MYOGLOBIN
(Physeter
catodon) 		5 / 12 ILE A 107
LEU A 104
HIS A  97
LEU A  86
ILE A 142
 HEM  A 154 ( 3.9A)
None
HEM  A 154 (-3.4A)
None
None
 1.14A 1kyvB-1a6gA:
undetectable
1kyvC-1a6gA:
undetectable		 1kyvB-1a6gA:
25.27
1kyvC-1a6gA:
25.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KYV_D_RBFD504_1
(6,7-DIMETHYL-8-RIBIT
YLLUMAZINE SYNTHASE)		 1a6g MYOGLOBIN
(Physeter
catodon) 		5 / 12 ILE A 107
LEU A 104
HIS A  97
LEU A  86
ILE A 142
 HEM  A 154 ( 3.9A)
None
HEM  A 154 (-3.4A)
None
None
 1.13A 1kyvC-1a6gA:
undetectable
1kyvD-1a6gA:
undetectable		 1kyvC-1a6gA:
25.27
1kyvD-1a6gA:
25.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KYV_E_RBFE505_1
(6,7-DIMETHYL-8-RIBIT
YLLUMAZINE SYNTHASE)		 1a6g MYOGLOBIN
(Physeter
catodon) 		5 / 12 ILE A 107
LEU A 104
HIS A  97
LEU A  86
ILE A 142
 HEM  A 154 ( 3.9A)
None
HEM  A 154 (-3.4A)
None
None
 1.15A 1kyvD-1a6gA:
undetectable
1kyvE-1a6gA:
undetectable		 1kyvD-1a6gA:
25.27
1kyvE-1a6gA:
25.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LH6_A_NIOA155_1
(LEGHEMOGLOBIN A
(NICOTINATE MET))		 1a6g MYOGLOBIN
(Physeter
catodon) 		5 / 7 PHE A  33
PHE A  43
PHE A  46
HIS A  64
HIS A  93
 None
HEM  A 154 ( 4.0A)
None
HEM  A 154 ( 4.1A)
HEM  A 154 (-3.3A)
 1.31A 1lh6A-1a6gA:
16.2		 1lh6A-1a6gA:
27.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LH6_A_NIOA155_1
(LEGHEMOGLOBIN A
(NICOTINATE MET))		 1a6g MYOGLOBIN
(Physeter
catodon) 		5 / 7 PHE A  43
PHE A  46
HIS A  64
VAL A  68
HIS A  93
 HEM  A 154 ( 4.0A)
None
HEM  A 154 ( 4.1A)
HEM  A 154 ( 3.9A)
HEM  A 154 (-3.3A)
 1.15A 1lh6A-1a6gA:
16.2		 1lh6A-1a6gA:
27.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UA1_A_08YA600_1
(CYTOCHROME P450 3A4)		 1a6g MYOGLOBIN
(Physeter
catodon) 		5 / 12 ASP A  20
ARG A  31
ARG A 118
ILE A 112
THR A  39
 None
None
None
None
HEM  A 154 (-4.1A)
 1.11A 3ua1A-1a6gA:
0.6		 3ua1A-1a6gA:
15.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V4T_A_ACTA504_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)		 1a6g MYOGLOBIN
(Physeter
catodon) 		3 / 3 THR A  70
VAL A  66
GLU A  18
 None
 0.71A 3v4tA-1a6gA:
undetectable
3v4tD-1a6gA:
undetectable		 3v4tA-1a6gA:
17.94
3v4tD-1a6gA:
17.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W67_D_VIVD301_0
(ALPHA-TOCOPHEROL
TRANSFER PROTEIN)		 1a6g MYOGLOBIN
(Physeter
catodon) 		5 / 12 LEU A  89
SER A  92
PHE A  43
ILE A  28
ILE A 107
 HEM  A 154 (-4.9A)
HEM  A 154 (-2.6A)
HEM  A 154 ( 4.0A)
None
HEM  A 154 ( 3.9A)
 1.29A 3w67D-1a6gA:
undetectable		 3w67D-1a6gA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O1Z_A_MXMA807_2
(PROSTAGLANDIN G/H
SYNTHASE 1)		 1a6g MYOGLOBIN
(Physeter
catodon) 		4 / 6 VAL A 114
LEU A 115
ARG A 118
LEU A  69
 None
 0.98A 4o1zA-1a6gA:
undetectable		 4o1zA-1a6gA:
13.42