SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1a6t'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	1ZEA_A_DHIA6_0 (MONOCLONAL ANTI-CHOLERA TOXIN IGG1 KAPPA ANTIBODY, H CHAIN MONOCLONAL ANTI-CHOLERA TOXIN IGG1 KAPPA ANTIBODY, L CHAIN SHORT SYNTHETIC D-AMINO ACID PEPTIDE D2)	1a6t	IGG1 FAB1-IA FAB (HEAVY CHAIN) (Mus musculus)	3 / 3	TRP B 47 ARG B 95 PHE B 100	None	1.35A	1zeaH-1a6tB: 26.3 1zeaL-1a6tB: 16.7	1zeaH-1a6tB: 67.74 1zeaL-1a6tB: 27.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3EJ8_B_H4BB2902_1 (NITRIC OXIDE SYNTHASE, INDUCIBLE)	1a6t	IGG1 FAB1-IA FAB (HEAVY CHAIN) (Mus musculus)	4 / 7	TRP B 36 PHE B 59 MET B 80 ILE B 68	None	1.44A	3ej8A-1a6tB: 0.0 3ej8B-1a6tB: undetectable	3ej8A-1a6tB: 18.79 3ej8B-1a6tB: 18.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3OU7_B_SAMB300_1 (SAM-DEPENDENT METHYLTRANSFERASE)	1a6t	IGG1 FAB1-IA FAB (HEAVY CHAIN) (Mus musculus)	3 / 3	TYR B 27 ASP B 101 ASP B 97	None	0.72A	3ou7B-1a6tB: undetectable	3ou7B-1a6tB: 22.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4Y0Q_A_PX9A201_0 (BETA-LACTOGLOBULIN)	1a6t	IGG1 FAB1-IA FAB (HEAVY CHAIN) (Mus musculus)	5 / 12	LEU B 159 VAL B 181 ILE B 210 LEU B 138 VAL B 206	None	1.12A	4y0qA-1a6tB: undetectable	4y0qA-1a6tB: 21.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5IK1_A_CAMA503_0 (CAMPHOR 5-MONOOXYGENASE)	1a6t	IGG1 FAB1-IA FAB (HEAVY CHAIN) (Mus musculus)	4 / 7	GLY B 82 VAL B 12 ASP B 10 VAL B 111	None	0.82A	5ik1A-1a6tB: undetectable	5ik1A-1a6tB: 20.00

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1ZEA_A_DHIA6_0","MONOCLONAL ANTI-CHOLERA TOXIN IGG1 KAPPA ANTIBODY, H CHAIN;MONOCLONAL ANTI-CHOLERA TOXIN IGG1 KAPPA ANTIBODY, L CHAIN;SHORT SYNTHETIC D-AMINO ACID PEPTIDE D2","1a6t","IGG1 FAB1-IA FAB (HEAVY CHAIN)","Mus musculus",3,"TRP B  47;ARG B  95;PHE B 100","None","1.35A","1zeaH-1a6tB:26.3;1zeaL-1a6tB:16.7","1zeaH-1a6tB:67.74;1zeaL-1a6tB:27.31"],["3EJ8_B_H4BB2902_1","NITRIC OXIDE SYNTHASE, INDUCIBLE;NITRIC OXIDE SYNTHASE, INDUCIBLE","1a6t","IGG1 FAB1-IA FAB (HEAVY CHAIN)","Mus musculus",4,"TRP B  36;PHE B  59;MET B  80;ILE B  68","None","1.44A","3ej8A-1a6tB:0.0;3ej8B-1a6tB:undetectable","3ej8A-1a6tB:18.79;3ej8B-1a6tB:18.79"],["3OU7_B_SAMB300_1","SAM-DEPENDENT METHYLTRANSFERASE","1a6t","IGG1 FAB1-IA FAB (HEAVY CHAIN)","Mus musculus",3,"TYR B  27;ASP B 101;ASP B  97","None","0.72A","3ou7B-1a6tB:undetectable","3ou7B-1a6tB:22.08"],["4Y0Q_A_PX9A201_0","BETA-LACTOGLOBULIN","1a6t","IGG1 FAB1-IA FAB (HEAVY CHAIN)","Mus musculus",5,"LEU B 159;VAL B 181;ILE B 210;LEU B 138;VAL B 206","None","1.12A","4y0qA-1a6tB:undetectable","4y0qA-1a6tB:21.83"],["5IK1_A_CAMA503_0","CAMPHOR 5-MONOOXYGENASE","1a6t","IGG1 FAB1-IA FAB (HEAVY CHAIN)","Mus musculus",4,"GLY B  82;VAL B  12;ASP B  10;VAL B 111","None","0.82A","5ik1A-1a6tB:undetectable","5ik1A-1a6tB:20.00"]]