SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1a75'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2I2Z_A_SALA1100_1
(SERUM ALBUMIN)		 1a75 PARVALBUMIN
(Merlangius
merlangus) 		4 / 5 LEU A 105
LEU A  63
ILE A  58
ILE A  50
 None
 0.75A 2i2zA-1a75A:
undetectable		 2i2zA-1a75A:
11.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EJG_B_NCTB501_1
(CYTOCHROME P450 2A13)		 1a75 PARVALBUMIN
(Merlangius
merlangus) 		4 / 8 PHE A  66
PHE A  85
PHE A  29
LEU A 105
 None
 0.82A 4ejgB-1a75A:
undetectable		 4ejgB-1a75A:
14.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XP9_C_1WEC706_1
(TRANSPORTER)		 1a75 PARVALBUMIN
(Merlangius
merlangus) 		4 / 4 PHE A  57
ASP A  51
GLY A  98
SER A  55
 None
CA  A 110 ( 3.1A)
None
CA  A 110 ( 2.4A)
 1.42A 4xp9C-1a75A:
0.0		 4xp9C-1a75A:
12.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IY5_P_CHDP307_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 1a75 PARVALBUMIN
(Merlangius
merlangus) 		4 / 5 ARG A  75
LEU A  67
PHE A  70
LEU A  77
 None
 1.20A 5iy5P-1a75A:
undetectable
5iy5W-1a75A:
0.0		 5iy5P-1a75A:
14.51
5iy5W-1a75A:
16.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1F_C_CHDC304_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 1a75 PARVALBUMIN
(Merlangius
merlangus) 		4 / 5 ARG A  75
LEU A  67
PHE A  70
LEU A  77
 None
 1.16A 5x1fC-1a75A:
undetectable
5x1fJ-1a75A:
0.0		 5x1fC-1a75A:
14.84
5x1fJ-1a75A:
15.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDX_C_CHDC308_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT VIIA-HEART)		 1a75 PARVALBUMIN
(Merlangius
merlangus) 		4 / 5 ARG A  75
LEU A  67
PHE A  70
LEU A  77
 None
 1.16A 5xdxC-1a75A:
undetectable
5xdxJ-1a75A:
undetectable		 5xdxC-1a75A:
14.45
5xdxJ-1a75A:
15.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDX_P_CHDP306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT VIIA-HEART)		 1a75 PARVALBUMIN
(Merlangius
merlangus) 		4 / 5 ARG A  75
LEU A  67
PHE A  70
LEU A  77
 None
 1.19A 5xdxP-1a75A:
undetectable
5xdxW-1a75A:
undetectable		 5xdxP-1a75A:
14.45
5xdxW-1a75A:
15.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XIW_B_LOCB504_2
(TUBULIN BETA CHAIN)		 1a75 PARVALBUMIN
(Merlangius
merlangus) 		5 / 12 LEU A  35
LEU A 105
ILE A  50
ALA A  46
ILE A  97
 None
 0.99A 5xiwB-1a75A:
undetectable		 5xiwB-1a75A:
18.10