SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1a7j'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z11_A_8MOA501_0
(CYTOCHROME P450,
FAMILY 2, SUBFAMILY
A, POLYPEPTIDE 6)		 1a7j PHOSPHORIBULOKINASE
(Rhodobacter
sphaeroides) 		5 / 11 PHE A  25
VAL A  21
ILE A 152
GLY A 153
LEU A 268
 None
 0.84A 1z11A-1a7jA:
0.0		 1z11A-1a7jA:
21.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z11_B_8MOB501_0
(CYTOCHROME P450,
FAMILY 2, SUBFAMILY
A, POLYPEPTIDE 6)		 1a7j PHOSPHORIBULOKINASE
(Rhodobacter
sphaeroides) 		5 / 11 PHE A  25
VAL A  21
ILE A 152
GLY A 153
LEU A 268
 None
 0.78A 1z11B-1a7jA:
0.0		 1z11B-1a7jA:
21.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z11_C_8MOC501_0
(CYTOCHROME P450,
FAMILY 2, SUBFAMILY
A, POLYPEPTIDE 6)		 1a7j PHOSPHORIBULOKINASE
(Rhodobacter
sphaeroides) 		5 / 10 PHE A  25
VAL A  21
ILE A 152
GLY A 153
LEU A 268
 None
 0.77A 1z11C-1a7jA:
0.0		 1z11C-1a7jA:
21.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z11_D_8MOD501_0
(CYTOCHROME P450,
FAMILY 2, SUBFAMILY
A, POLYPEPTIDE 6)		 1a7j PHOSPHORIBULOKINASE
(Rhodobacter
sphaeroides) 		5 / 10 PHE A  25
VAL A  21
ILE A 152
GLY A 153
LEU A 268
 None
 0.86A 1z11D-1a7jA:
0.0		 1z11D-1a7jA:
21.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BDM_A_TMIA502_1
(CYTOCHROME P450 2B4)		 1a7j PHOSPHORIBULOKINASE
(Rhodobacter
sphaeroides) 		5 / 12 LEU A 127
ILE A 152
LEU A 276
THR A 277
LEU A 279
 None
 0.71A 2bdmA-1a7jA:
0.0		 2bdmA-1a7jA:
21.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIN_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)		 1a7j PHOSPHORIBULOKINASE
(Rhodobacter
sphaeroides) 		4 / 8 ILE A 233
PHE A 235
THR A 277
LEU A 276
 None
 0.81A 2einA-1a7jA:
undetectable
2einJ-1a7jA:
undetectable		 2einA-1a7jA:
20.11
2einJ-1a7jA:
12.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZIF_B_SAMB298_1
(PUTATIVE
MODIFICATION
METHYLASE)		 1a7j PHOSPHORIBULOKINASE
(Rhodobacter
sphaeroides) 		3 / 3 ASP A 169
THR A  11
GLU A 161
 None
 0.76A 2zifB-1a7jA:
undetectable		 2zifB-1a7jA:
23.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MDT_A_VORA506_1
(CHOLESTEROL
24-HYDROXYLASE)		 1a7j PHOSPHORIBULOKINASE
(Rhodobacter
sphaeroides) 		5 / 9 PHE A 206
VAL A 231
ILE A 275
ALA A 271
THR A  24
 None
 1.32A 3mdtA-1a7jA:
undetectable		 3mdtA-1a7jA:
22.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SUF_B_SUEB1201_3
(NS3 PROTEASE, NS4A
PROTEIN)		 1a7j PHOSPHORIBULOKINASE
(Rhodobacter
sphaeroides) 		4 / 5 SER A 229
ARG A 208
PRO A 156
VAL A 157
 None
 1.13A 3sufC-1a7jA:
0.0		 3sufC-1a7jA:
21.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3R_A_9PLA501_1
(CYTOCHROME P450 2A6)		 1a7j PHOSPHORIBULOKINASE
(Rhodobacter
sphaeroides) 		5 / 11 PHE A  25
VAL A  21
ILE A 152
GLY A 153
LEU A 268
 None
 0.82A 3t3rA-1a7jA:
0.0		 3t3rA-1a7jA:
21.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UA5_A_06XA501_1
(CYTOCHROME P450 2B6)		 1a7j PHOSPHORIBULOKINASE
(Rhodobacter
sphaeroides) 		4 / 8 ILE A 261
ILE A 241
PHE A 243
LEU A 276
 None
 0.87A 3ua5A-1a7jA:
0.0		 3ua5A-1a7jA:
21.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F8H_A_RKEA401_1
(PROTON-GATED ION
CHANNEL)		 1a7j PHOSPHORIBULOKINASE
(Rhodobacter
sphaeroides) 		4 / 8 ASP A 269
VAL A 154
PHE A  25
LEU A 276
 None
 0.92A 4f8hA-1a7jA:
undetectable
4f8hB-1a7jA:
undetectable		 4f8hA-1a7jA:
23.08
4f8hB-1a7jA:
23.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F8H_B_RKEB401_1
(PROTON-GATED ION
CHANNEL)		 1a7j PHOSPHORIBULOKINASE
(Rhodobacter
sphaeroides) 		4 / 8 ASP A 269
VAL A 154
PHE A  25
LEU A 276
 None
 0.92A 4f8hB-1a7jA:
undetectable
4f8hC-1a7jA:
undetectable		 4f8hB-1a7jA:
23.08
4f8hC-1a7jA:
23.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F8H_C_RKEC401_1
(PROTON-GATED ION
CHANNEL)		 1a7j PHOSPHORIBULOKINASE
(Rhodobacter
sphaeroides) 		4 / 8 ASP A 269
VAL A 154
PHE A  25
LEU A 276
 None
 0.93A 4f8hC-1a7jA:
undetectable
4f8hD-1a7jA:
undetectable		 4f8hC-1a7jA:
23.08
4f8hD-1a7jA:
23.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F8H_D_RKED401_1
(PROTON-GATED ION
CHANNEL)		 1a7j PHOSPHORIBULOKINASE
(Rhodobacter
sphaeroides) 		4 / 8 ASP A 269
VAL A 154
PHE A  25
LEU A 276
 None
 0.92A 4f8hD-1a7jA:
0.0
4f8hE-1a7jA:
0.0		 4f8hD-1a7jA:
23.08
4f8hE-1a7jA:
23.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F8H_E_RKEE401_1
(PROTON-GATED ION
CHANNEL)		 1a7j PHOSPHORIBULOKINASE
(Rhodobacter
sphaeroides) 		4 / 8 VAL A 154
PHE A  25
LEU A 276
ASP A 269
 None
 0.94A 4f8hA-1a7jA:
undetectable
4f8hE-1a7jA:
undetectable		 4f8hA-1a7jA:
23.08
4f8hE-1a7jA:
23.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RP8_C_ASCC501_0
(ASCORBATE-SPECIFIC
PERMEASE IIC
COMPONENT ULAA)		 1a7j PHOSPHORIBULOKINASE
(Rhodobacter
sphaeroides) 		5 / 12 LEU A 150
ILE A 275
ILE A   8
ILE A  28
PHE A  25
 None
 1.23A 4rp8C-1a7jA:
0.0		 4rp8C-1a7jA:
20.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_R_BEZR801_0
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 2
BEZ-LEU-LEU)		 1a7j PHOSPHORIBULOKINASE
(Rhodobacter
sphaeroides) 		4 / 7 SER A 229
ALA A 226
PRO A 264
LEU A 268
 None
 1.12A 5dzkD-1a7jA:
undetectable
5dzkR-1a7jA:
undetectable		 5dzkD-1a7jA:
21.77
5dzkR-1a7jA:
1.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N5D_B_SAMB303_1
(METHYLTRANSFERASE)		 1a7j PHOSPHORIBULOKINASE
(Rhodobacter
sphaeroides) 		4 / 7 GLY A  41
SER A  14
ARG A  94
ASP A  42
 None
 0.98A 5n5dB-1a7jA:
undetectable		 5n5dB-1a7jA:
23.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EBZ_A_DAHA123_0
(RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE,
BETA SUBUNIT)		 1a7j PHOSPHORIBULOKINASE
(Rhodobacter
sphaeroides) 		5 / 11 PHE A  84
GLY A  88
ILE A   7
PHE A  44
ILE A  39
 None
 0.82A 6ebzA-1a7jA:
undetectable		 6ebzA-1a7jA:
16.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EBZ_B_DAHB123_0
(RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE,
BETA SUBUNIT)		 1a7j PHOSPHORIBULOKINASE
(Rhodobacter
sphaeroides) 		5 / 11 PHE A  84
GLY A  88
ILE A   7
PHE A  44
ILE A  39
 None
 0.84A 6ebzB-1a7jA:
undetectable		 6ebzB-1a7jA:
16.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EBZ_C_DAHC123_0
(RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE,
BETA SUBUNIT)		 1a7j PHOSPHORIBULOKINASE
(Rhodobacter
sphaeroides) 		5 / 11 PHE A  84
GLY A  88
ILE A   7
PHE A  44
ILE A  39
 None
 0.84A 6ebzC-1a7jA:
undetectable		 6ebzC-1a7jA:
16.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EBZ_D_DAHD123_0
(RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE,
BETA SUBUNIT)		 1a7j PHOSPHORIBULOKINASE
(Rhodobacter
sphaeroides) 		5 / 11 PHE A  84
GLY A  88
ILE A   7
PHE A  44
ILE A  39
 None
 0.84A 6ebzD-1a7jA:
undetectable		 6ebzD-1a7jA:
16.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GP2_A_DAHA126_0
(RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
BETA CHAIN)		 1a7j PHOSPHORIBULOKINASE
(Rhodobacter
sphaeroides) 		5 / 11 PHE A  84
GLY A  88
ILE A   7
PHE A  44
ILE A  39
 None
 0.87A 6gp2A-1a7jA:
undetectable		 6gp2A-1a7jA:
16.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GP2_B_DAHB126_0
(RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
BETA CHAIN)		 1a7j PHOSPHORIBULOKINASE
(Rhodobacter
sphaeroides) 		5 / 11 PHE A  84
GLY A  88
ILE A   7
PHE A  44
ILE A  39
 None
 0.90A 6gp2B-1a7jA:
undetectable		 6gp2B-1a7jA:
16.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MVX_A_K4DA1304_0
(ION TRANSPORT
PROTEIN)		 1a7j PHOSPHORIBULOKINASE
(Rhodobacter
sphaeroides) 		4 / 6 THR A 277
LEU A 279
THR A  24
LEU A 127
 None
 1.22A 6mvxA-1a7jA:
undetectable
6mvxB-1a7jA:
undetectable
6mvxC-1a7jA:
undetectable		 6mvxA-1a7jA:
19.28
6mvxB-1a7jA:
19.28
6mvxC-1a7jA:
19.28