SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1a87'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1USQ_B_CLMB1143_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 1a87 COLICIN N
(Escherichia
coli) 		4 / 6 PRO A 101
PRO A 106
GLY A 107
TYR A 109
 None
 0.82A 1usqB-1a87A:
undetectable		 1usqB-1a87A:
19.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1USQ_C_CLMC1143_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 1a87 COLICIN N
(Escherichia
coli) 		4 / 6 PRO A 101
PRO A 106
GLY A 107
TYR A 109
 None
 0.82A 1usqC-1a87A:
0.0		 1usqC-1a87A:
19.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1USQ_D_CLMD1142_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 1a87 COLICIN N
(Escherichia
coli) 		4 / 6 PRO A 101
PRO A 106
GLY A 107
TYR A 109
 None
 0.84A 1usqD-1a87A:
undetectable		 1usqD-1a87A:
19.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1USQ_F_CLMF1144_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 1a87 COLICIN N
(Escherichia
coli) 		4 / 7 PRO A 101
PRO A 106
GLY A 107
TYR A 109
 None
 0.83A 1usqF-1a87A:
undetectable		 1usqF-1a87A:
19.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3A_A_TEPA1434_1
(CHITINASE)		 1a87 COLICIN N
(Escherichia
coli) 		3 / 3 TRP A 270
THR A 362
TYR A 365
 None
 1.21A 2a3aA-1a87A:
undetectable		 2a3aA-1a87A:
22.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3A_B_TEPB2434_1
(CHITINASE)		 1a87 COLICIN N
(Escherichia
coli) 		3 / 3 TRP A 270
THR A 362
TYR A 365
 None
 1.25A 2a3aB-1a87A:
undetectable		 2a3aB-1a87A:
22.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3B_A_CFFA1434_1
(CHITINASE)		 1a87 COLICIN N
(Escherichia
coli) 		3 / 3 TRP A 270
THR A 362
TYR A 365
 None
 1.24A 2a3bA-1a87A:
undetectable		 2a3bA-1a87A:
22.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JKJ_A_CLMA1141_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 1a87 COLICIN N
(Escherichia
coli) 		4 / 6 PRO A 101
PRO A 106
GLY A 107
TYR A 109
 None
 0.83A 2jkjA-1a87A:
undetectable		 2jkjA-1a87A:
19.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JKJ_B_CLMB1141_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 1a87 COLICIN N
(Escherichia
coli) 		4 / 6 PRO A 101
PRO A 106
GLY A 107
TYR A 109
 None
 0.83A 2jkjB-1a87A:
undetectable		 2jkjB-1a87A:
19.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JKJ_C_CLMC1141_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 1a87 COLICIN N
(Escherichia
coli) 		4 / 6 PRO A 101
PRO A 106
GLY A 107
TYR A 109
 None
 0.83A 2jkjC-1a87A:
undetectable		 2jkjC-1a87A:
19.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JKJ_D_CLMD1142_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 1a87 COLICIN N
(Escherichia
coli) 		4 / 5 PRO A 101
PRO A 106
GLY A 107
TYR A 109
 None
 0.82A 2jkjD-1a87A:
undetectable		 2jkjD-1a87A:
19.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JKJ_E_CLME1141_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 1a87 COLICIN N
(Escherichia
coli) 		4 / 7 PRO A 101
PRO A 106
GLY A 107
TYR A 109
 None
 0.82A 2jkjE-1a87A:
undetectable		 2jkjE-1a87A:
19.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JKJ_F_CLMF1143_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 1a87 COLICIN N
(Escherichia
coli) 		4 / 5 PRO A 101
PRO A 106
GLY A 107
TYR A 109
 None
 0.83A 2jkjF-1a87A:
undetectable		 2jkjF-1a87A:
19.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JKL_B_CLMB1144_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 1a87 COLICIN N
(Escherichia
coli) 		4 / 6 PRO A 101
PRO A 106
GLY A 107
TYR A 109
 None
 0.82A 2jklB-1a87A:
undetectable		 2jklB-1a87A:
19.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JKL_E_CLME1143_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 1a87 COLICIN N
(Escherichia
coli) 		4 / 7 PRO A 101
PRO A 106
GLY A 107
TYR A 109
 None
 0.82A 2jklE-1a87A:
undetectable		 2jklE-1a87A:
19.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QO4_A_CHDA130_0
(LIVER-BASIC FATTY
ACID BINDING PROTEIN)		 1a87 COLICIN N
(Escherichia
coli) 		5 / 12 LEU A 350
ILE A 347
VAL A 258
THR A 362
MET A 361
 None
 1.25A 2qo4A-1a87A:
2.4		 2qo4A-1a87A:
15.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RF4_A_FUNA201_1
(MACROPHAGE MIGRATION
INHIBITORY FACTOR)		 1a87 COLICIN N
(Escherichia
coli) 		5 / 11 SER A 364
ILE A 363
VAL A 225
VAL A 203
ILE A 370
 None
 1.23A 3rf4A-1a87A:
undetectable
3rf4C-1a87A:
undetectable		 3rf4A-1a87A:
15.61
3rf4C-1a87A:
15.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RF4_B_FUNB202_1
(MACROPHAGE MIGRATION
INHIBITORY FACTOR)		 1a87 COLICIN N
(Escherichia
coli) 		5 / 11 ILE A 370
SER A 364
ILE A 363
VAL A 225
VAL A 203
 None
 1.23A 3rf4A-1a87A:
undetectable
3rf4B-1a87A:
undetectable		 3rf4A-1a87A:
15.61
3rf4B-1a87A:
15.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RF4_C_FUNC203_1
(MACROPHAGE MIGRATION
INHIBITORY FACTOR)		 1a87 COLICIN N
(Escherichia
coli) 		5 / 11 ILE A 370
SER A 364
ILE A 363
VAL A 225
VAL A 203
 None
 1.24A 3rf4B-1a87A:
undetectable
3rf4C-1a87A:
undetectable		 3rf4B-1a87A:
15.61
3rf4C-1a87A:
15.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A97_F_ZPCF1318_1
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 1a87 COLICIN N
(Escherichia
coli) 		5 / 12 GLU A 187
PHE A 183
HIS A 137
TYR A 109
ILE A  97
 None
 1.30A 4a97F-1a87A:
0.0
4a97J-1a87A:
0.0		 4a97F-1a87A:
21.10
4a97J-1a87A:
21.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A97_F_ZPCF1318_1
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 1a87 COLICIN N
(Escherichia
coli) 		5 / 12 GLU A 187
PHE A 183
TYR A 134
TYR A 109
ILE A  97
 None
 1.15A 4a97F-1a87A:
0.0
4a97J-1a87A:
0.0		 4a97F-1a87A:
21.10
4a97J-1a87A:
21.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IKJ_B_SUZB201_1
(TRANSTHYRETIN)		 1a87 COLICIN N
(Escherichia
coli) 		4 / 8 SER A 367
ALA A 245
LEU A 247
SER A 368
 None
 0.89A 4ikjA-1a87A:
undetectable
4ikjB-1a87A:
undetectable		 4ikjA-1a87A:
18.99
4ikjB-1a87A:
18.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IKK_A_SUZA201_1
(TRANSTHYRETIN)		 1a87 COLICIN N
(Escherichia
coli) 		4 / 8 ALA A 245
LEU A 247
SER A 368
SER A 367
 None
 0.83A 4ikkA-1a87A:
undetectable
4ikkB-1a87A:
undetectable		 4ikkA-1a87A:
18.99
4ikkB-1a87A:
18.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RVD_A_SAMA502_0
(D-MYCAROSE
3-C-METHYLTRANSFERAS
E)		 1a87 COLICIN N
(Escherichia
coli) 		5 / 12 ILE A 335
GLY A 332
ALA A 288
HIS A 233
ILE A 229
 None
 1.07A 4rvdA-1a87A:
undetectable		 4rvdA-1a87A:
20.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z69_A_DIFA1008_1
(SERUM ALBUMIN)		 1a87 COLICIN N
(Escherichia
coli) 		5 / 9 PHE A 289
VAL A 329
SER A 336
LEU A 337
VAL A 333
 None
 1.42A 4z69A-1a87A:
3.0		 4z69A-1a87A:
18.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5F1A_A_SALA601_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 1a87 COLICIN N
(Escherichia
coli) 		4 / 8 LEU A 366
GLY A 339
ALA A 340
SER A 343
 None
 0.57A 5f1aA-1a87A:
0.0		 5f1aA-1a87A:
20.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5F1A_B_SALB601_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 1a87 COLICIN N
(Escherichia
coli) 		4 / 7 LEU A 366
GLY A 339
ALA A 340
SER A 343
 None
 0.56A 5f1aB-1a87A:
0.0		 5f1aB-1a87A:
20.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NWU_A_ACAA18_1
(WTFP-TAG,GP41)		 1a87 COLICIN N
(Escherichia
coli) 		5 / 12 LYS A 190
ASN A 191
GLU A 192
GLU A 194
LEU A 196
 None
 1.27A 5nwuA-1a87A:
0.0		 5nwuA-1a87A:
12.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6C2M_A_SUEA1202_1
(NS3 PROTEASE)		 1a87 COLICIN N
(Escherichia
coli) 		5 / 9 ASP A 102
ARG A 108
ALA A 125
SER A 127
ASP A 124
 None
 1.14A 6c2mA-1a87A:
0.0		 6c2mA-1a87A:
10.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6C2M_B_SUEB1202_1
(NS3 PROTEASE)		 1a87 COLICIN N
(Escherichia
coli) 		5 / 9 ASP A 102
ARG A 108
ALA A 125
SER A 127
ASP A 124
 None
 1.14A 6c2mB-1a87A:
undetectable		 6c2mB-1a87A:
10.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NM4_B_SAMB402_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
PRDM9)		 1a87 COLICIN N
(Escherichia
coli) 		5 / 9 ILE A 282
ALA A 340
GLY A 339
LEU A 342
GLY A 205
 None
 1.08A 6nm4B-1a87A:
undetectable		 6nm4B-1a87A:
18.89