SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1a88'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MXG_A_ACRA444_1
(ALPHA AMYLASE)		 1a88 CHLOROPEROXIDASE L
(Streptomyces
lividans) 		4 / 7 TYR A 166
TRP A 183
HIS A 195
GLY A  60
 None
 1.32A 1mxgA-1a88A:
undetectable		 1mxgA-1a88A:
19.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P33_D_MTXD354_1
(PTERIDINE REDUCTASE
1)		 1a88 CHLOROPEROXIDASE L
(Streptomyces
lividans) 		5 / 12 PHE A 168
PRO A 161
LEU A 179
LEU A 253
PRO A 254
 None
 1.47A 1p33D-1a88A:
5.1		 1p33D-1a88A:
23.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1S3Z_B_RIOB501_0
(AMINOGLYCOSIDE
6'-N-ACETYLTRANSFERA
SE)		 1a88 CHLOROPEROXIDASE L
(Streptomyces
lividans) 		4 / 8 GLU A 101
VAL A  78
TRP A  37
HIS A  95
 None
 1.30A 1s3zA-1a88A:
0.5
1s3zB-1a88A:
0.5		 1s3zA-1a88A:
20.66
1s3zB-1a88A:
20.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BFP_B_H4BB1290_1
(PTERIDINE REDUCTASE
1)		 1a88 CHLOROPEROXIDASE L
(Streptomyces
lividans) 		4 / 8 SER A  46
PHE A  44
LEU A 265
LEU A 258
 None
 0.92A 2bfpB-1a88A:
5.2		 2bfpB-1a88A:
22.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BFP_C_H4BC1290_1
(PTERIDINE REDUCTASE
1)		 1a88 CHLOROPEROXIDASE L
(Streptomyces
lividans) 		4 / 8 SER A  46
PHE A  44
LEU A 265
LEU A 258
 None
 1.00A 2bfpC-1a88A:
5.2		 2bfpC-1a88A:
22.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J2P_E_SC2E1289_1
(FICOLIN-2)		 1a88 CHLOROPEROXIDASE L
(Streptomyces
lividans) 		4 / 6 ARG A  57
ASP A  70
THR A  73
ASP A   7
 None
 0.76A 2j2pE-1a88A:
0.0
2j2pF-1a88A:
0.1		 2j2pE-1a88A:
21.91
2j2pF-1a88A:
21.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y05_A_RALA802_1
(PROSTAGLANDIN
REDUCTASE 1)		 1a88 CHLOROPEROXIDASE L
(Streptomyces
lividans) 		4 / 7 VAL A  78
TYR A 105
GLY A  94
VAL A  25
 None
 0.91A 2y05A-1a88A:
3.6
2y05B-1a88A:
3.6		 2y05A-1a88A:
22.94
2y05B-1a88A:
22.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZZN_B_SAMB402_0
(UNCHARACTERIZED
PROTEIN MJ0883)		 1a88 CHLOROPEROXIDASE L
(Streptomyces
lividans) 		5 / 12 LEU A  85
ARG A  50
GLY A  89
PRO A  23
ASP A 215
 None
 1.33A 2zznB-1a88A:
undetectable		 2zznB-1a88A:
18.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DCM_X_SAMX5452_0
(UNCHARACTERIZED
PROTEIN TM_1570)		 1a88 CHLOROPEROXIDASE L
(Streptomyces
lividans) 		6 / 11 ALA A 103
GLY A  94
GLY A  98
ILE A 214
VAL A 118
ALA A 117
 None
 1.41A 3dcmX-1a88A:
2.2		 3dcmX-1a88A:
19.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DQT_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 1a88 CHLOROPEROXIDASE L
(Streptomyces
lividans) 		4 / 7 PHE A 207
GLU A 204
SER A 203
ARG A 104
 None
 1.39A 3dqtA-1a88A:
0.0
3dqtB-1a88A:
0.0		 3dqtA-1a88A:
21.45
3dqtB-1a88A:
21.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HCP_B_CHDB4_0
(FERROCHELATASE,
MITOCHONDRIAL)		 1a88 CHLOROPEROXIDASE L
(Streptomyces
lividans) 		3 / 3 GLY A  98
PRO A 124
LEU A 119
 None
 0.63A 3hcpB-1a88A:
2.8		 3hcpB-1a88A:
21.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LB3_A_4CHA191_0
(DEHALOPEROXIDASE A)		 1a88 CHLOROPEROXIDASE L
(Streptomyces
lividans) 		4 / 6 PHE A 202
HIS A  95
THR A  97
VAL A 123
 None
 1.13A 3lb3A-1a88A:
0.1		 3lb3A-1a88A:
17.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LB3_B_4CHB192_0
(DEHALOPEROXIDASE A)		 1a88 CHLOROPEROXIDASE L
(Streptomyces
lividans) 		4 / 6 PHE A 202
HIS A  95
THR A  97
VAL A 123
 None
 1.18A 3lb3B-1a88A:
0.0		 3lb3B-1a88A:
17.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N5T_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE)		 1a88 CHLOROPEROXIDASE L
(Streptomyces
lividans) 		4 / 7 SER A 203
ARG A 104
PHE A 207
GLU A 204
 None
 1.38A 3n5tA-1a88A:
0.0
3n5tB-1a88A:
undetectable		 3n5tA-1a88A:
20.36
3n5tB-1a88A:
20.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RQL_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1a88 CHLOROPEROXIDASE L
(Streptomyces
lividans) 		4 / 8 PHE A 207
GLU A 204
SER A 203
ARG A 104
 None
 1.37A 3rqlA-1a88A:
0.0
3rqlB-1a88A:
0.0		 3rqlA-1a88A:
21.83
3rqlB-1a88A:
21.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CAP_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1a88 CHLOROPEROXIDASE L
(Streptomyces
lividans) 		4 / 8 PHE A 207
GLU A 204
SER A 203
ARG A 104
 None
 1.39A 4capA-1a88A:
0.0
4capB-1a88A:
0.0		 4capA-1a88A:
21.83
4capB-1a88A:
21.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D32_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1a88 CHLOROPEROXIDASE L
(Streptomyces
lividans) 		4 / 8 PHE A 207
GLU A 204
SER A 203
ARG A 104
 None
 1.37A 4d32A-1a88A:
0.0
4d32B-1a88A:
0.0		 4d32A-1a88A:
21.83
4d32B-1a88A:
21.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JQ1_B_NPSB401_1
(ALDO-KETO REDUCTASE
FAMILY 1 MEMBER C2)		 1a88 CHLOROPEROXIDASE L
(Streptomyces
lividans) 		4 / 8 VAL A 114
HIS A  92
VAL A 216
ILE A 214
 None
 0.86A 4jq1B-1a88A:
undetectable		 4jq1B-1a88A:
20.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K0B_B_SAMB504_1
(S-ADENOSYLMETHIONINE
SYNTHASE)		 1a88 CHLOROPEROXIDASE L
(Streptomyces
lividans) 		4 / 8 ASP A  55
LYS A  14
ALA A  53
SER A  33
 None
 1.06A 4k0bB-1a88A:
undetectable		 4k0bB-1a88A:
21.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K5J_B_H4BB502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 1a88 CHLOROPEROXIDASE L
(Streptomyces
lividans) 		4 / 7 PHE A 207
GLU A 204
SER A 203
ARG A 104
 None
 1.34A 4k5jA-1a88A:
0.0
4k5jB-1a88A:
0.0		 4k5jA-1a88A:
20.41
4k5jB-1a88A:
20.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L7I_B_SAMB501_1
(S-ADENOSYLMETHIONINE
SYNTHASE)		 1a88 CHLOROPEROXIDASE L
(Streptomyces
lividans) 		4 / 8 ASP A  55
LYS A  14
ALA A  53
SER A  33
 None
 1.07A 4l7iB-1a88A:
undetectable		 4l7iB-1a88A:
21.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N48_B_SAMB601_1
(CAP-SPECIFIC MRNA
(NUCLEOSIDE-2'-O-)-M
ETHYLTRANSFERASE 1)		 1a88 CHLOROPEROXIDASE L
(Streptomyces
lividans) 		4 / 5 ASN A 169
PRO A 164
GLY A 167
ASP A 225
 None
 1.15A 4n48B-1a88A:
2.2		 4n48B-1a88A:
20.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N49_A_SAMA601_1
(CAP-SPECIFIC MRNA
(NUCLEOSIDE-2'-O-)-M
ETHYLTRANSFERASE 1)		 1a88 CHLOROPEROXIDASE L
(Streptomyces
lividans) 		4 / 4 ASN A 169
GLY A 167
ASP A 233
ASP A 225
 None
 1.21A 4n49A-1a88A:
2.2		 4n49A-1a88A:
20.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V3Y_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1a88 CHLOROPEROXIDASE L
(Streptomyces
lividans) 		4 / 8 PHE A 207
GLU A 204
SER A 203
ARG A 104
 None
 1.38A 4v3yA-1a88A:
0.0
4v3yB-1a88A:
0.0		 4v3yA-1a88A:
21.83
4v3yB-1a88A:
21.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ADL_B_H4BB600_1
(ENDOTHELIAL NITRIC
OXIDE SYNTHASE)		 1a88 CHLOROPEROXIDASE L
(Streptomyces
lividans) 		4 / 7 PHE A 207
GLU A 204
SER A 203
ARG A 104
 None
 1.35A 5adlA-1a88A:
0.0
5adlB-1a88A:
0.0		 5adlA-1a88A:
20.41
5adlB-1a88A:
20.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FJ3_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 1a88 CHLOROPEROXIDASE L
(Streptomyces
lividans) 		4 / 7 PHE A 207
GLU A 204
SER A 203
ARG A 104
 None
 1.35A 5fj3A-1a88A:
0.0
5fj3B-1a88A:
0.0		 5fj3A-1a88A:
20.41
5fj3B-1a88A:
20.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HWA_A_GCSA302_1
(CHITOSANASE)		 1a88 CHLOROPEROXIDASE L
(Streptomyces
lividans) 		4 / 7 THR A   5
ASP A  77
ASP A   7
GLY A  68
 None
 1.12A 5hwaA-1a88A:
0.0		 5hwaA-1a88A:
18.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JQ7_B_T0RB705_2
(ENVELOPE
GLYCOPROTEIN 2)		 1a88 CHLOROPEROXIDASE L
(Streptomyces
lividans) 		4 / 7 LEU A 219
THR A 224
ASP A 226
LEU A 269
 None
 0.92A 5jq7B-1a88A:
undetectable		 5jq7B-1a88A:
18.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OGJ_B_ACTB305_0
(CARBONIC ANHYDRASE
13)		 1a88 CHLOROPEROXIDASE L
(Streptomyces
lividans) 		4 / 6 HIS A  27
HIS A  92
LEU A  81
THR A  82
 None
 1.20A 5ogjB-1a88A:
undetectable		 5ogjB-1a88A:
21.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OHH_A_ACTA307_0
(CARBONIC ANHYDRASE
13)		 1a88 CHLOROPEROXIDASE L
(Streptomyces
lividans) 		4 / 5 HIS A  27
HIS A  92
LEU A  81
THR A  82
 None
 1.19A 5ohhA-1a88A:
undetectable		 5ohhA-1a88A:
21.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UO8_A_H4BA502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 1a88 CHLOROPEROXIDASE L
(Streptomyces
lividans) 		4 / 6 SER A 203
ARG A 104
PHE A 207
GLU A 204
 None
 1.34A 5uo8A-1a88A:
0.0
5uo8B-1a88A:
0.0		 5uo8A-1a88A:
20.78
5uo8B-1a88A:
20.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VV7_B_H4BB502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 1a88 CHLOROPEROXIDASE L
(Streptomyces
lividans) 		4 / 7 PHE A 207
GLU A 204
SER A 203
ARG A 104
 None
 1.33A 5vv7A-1a88A:
0.0
5vv7B-1a88A:
0.0		 5vv7A-1a88A:
20.41
5vv7B-1a88A:
20.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VVN_B_H4BB502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 1a88 CHLOROPEROXIDASE L
(Streptomyces
lividans) 		4 / 7 PHE A 207
GLU A 204
SER A 203
ARG A 104
 None
 1.36A 5vvnA-1a88A:
0.0
5vvnB-1a88A:
0.0		 5vvnA-1a88A:
20.41
5vvnB-1a88A:
20.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z6J_A_FOLA201_1
(DIHYDROFOLATE
REDUCTASE)		 1a88 CHLOROPEROXIDASE L
(Streptomyces
lividans) 		3 / 3 MET A  41
ASP A  35
ARG A  56
 None
 0.87A 5z6jA-1a88A:
1.5		 5z6jA-1a88A:
20.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z6K_A_FOLA201_1
(DIHYDROFOLATE
REDUCTASE)		 1a88 CHLOROPEROXIDASE L
(Streptomyces
lividans) 		3 / 3 MET A  41
ASP A  35
ARG A  56
 None
 1.04A 5z6kA-1a88A:
1.5		 5z6kA-1a88A:
20.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZHM_B_SAMB301_1
(TRNA
(GUANINE-N(1)-)-METH
YLTRANSFERASE)		 1a88 CHLOROPEROXIDASE L
(Streptomyces
lividans) 		6 / 12 GLY A  29
VAL A 120
LEU A 119
GLY A  99
GLY A 100
PRO A 124
 None
 1.30A 5zhmB-1a88A:
2.5		 5zhmB-1a88A:
22.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AV6_B_H4BB501_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 1a88 CHLOROPEROXIDASE L
(Streptomyces
lividans) 		4 / 7 SER A 203
ARG A 104
PHE A 207
GLU A 204
 None
 1.30A 6av6A-1a88A:
0.0
6av6B-1a88A:
0.0		 6av6A-1a88A:
15.25
6av6B-1a88A:
15.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AV6_D_H4BD502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 1a88 CHLOROPEROXIDASE L
(Streptomyces
lividans) 		4 / 7 PHE A 207
GLU A 204
SER A 203
ARG A 104
 None
 1.25A 6av6C-1a88A:
0.0
6av6D-1a88A:
0.0		 6av6C-1a88A:
15.25
6av6D-1a88A:
15.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AV7_A_H4BA502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 1a88 CHLOROPEROXIDASE L
(Streptomyces
lividans) 		4 / 7 SER A 203
ARG A 104
PHE A 207
GLU A 204
 None
 1.32A 6av7A-1a88A:
0.0
6av7B-1a88A:
0.0		 6av7A-1a88A:
15.25
6av7B-1a88A:
15.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MXT_A_K5YA1401_0
(ENDOLYSIN, BETA-2
ADRENERGIC RECEPTOR
CHIMERA)		 1a88 CHLOROPEROXIDASE L
(Streptomyces
lividans) 		5 / 12 VAL A 228
VAL A 229
ASP A 143
PHE A 145
PHE A 202
 None
 1.39A 6mxtA-1a88A:
undetectable		 6mxtA-1a88A:
20.99