SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1a97'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YFB_A_ACTA501_0
(METHYL-ACCEPTING
CHEMOTAXIS
TRANSDUCER)		 1a97 XANTHINE-GUANINE
PHOSPHORIBOSYLTRANSF
ERASE
(Escherichia
coli) 		4 / 7 MET A 103
VAL A  58
ILE A  60
TYR A 104
 None
 0.93A 2yfbA-1a97A:
undetectable		 2yfbA-1a97A:
17.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ACB_C_DXCC1477_0
(TRANSLATION
ELONGATION FACTOR
SELB)		 1a97 XANTHINE-GUANINE
PHOSPHORIBOSYLTRANSF
ERASE
(Escherichia
coli) 		4 / 6 GLY A  43
ARG A  53
ILE A  32
LEU A  19
 None
 0.85A 4acbC-1a97A:
undetectable		 4acbC-1a97A:
15.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EB6_C_VLBC503_1
(TUBULIN BETA CHAIN
TUBULIN ALPHA CHAIN)		 1a97 XANTHINE-GUANINE
PHOSPHORIBOSYLTRANSF
ERASE
(Escherichia
coli) 		5 / 12 VAL A  41
THR A 111
ILE A  52
VAL A  55
ILE A  33
 None
 1.33A 4eb6B-1a97A:
undetectable
4eb6C-1a97A:
undetectable		 4eb6B-1a97A:
16.46
4eb6C-1a97A:
14.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OLT_A_GCSA303_1
(CHITOSANASE)		 1a97 XANTHINE-GUANINE
PHOSPHORIBOSYLTRANSF
ERASE
(Escherichia
coli) 		4 / 6 ILE A  33
ASP A  56
GLY A  79
HIS A  54
 None
 1.02A 4oltA-1a97A:
undetectable		 4oltA-1a97A:
22.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OLT_B_GCSB303_1
(CHITOSANASE)		 1a97 XANTHINE-GUANINE
PHOSPHORIBOSYLTRANSF
ERASE
(Escherichia
coli) 		4 / 6 ILE A  33
ASP A  56
GLY A  79
HIS A  54
 None
 0.95A 4oltB-1a97A:
0.0		 4oltB-1a97A:
22.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B3A_A_SAMA701_0
(APRA
METHYLTRANSFERASE 1)		 1a97 XANTHINE-GUANINE
PHOSPHORIBOSYLTRANSF
ERASE
(Escherichia
coli) 		5 / 12 PHE A 109
GLY A 118
ALA A 117
ILE A 135
LEU A  90
 None
 1.03A 6b3aA-1a97A:
2.6		 6b3aA-1a97A:
13.17