SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1a9x'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_D_TRPD81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 1a9x CARBAMOYL PHOSPHATE
SYNTHETASE (SMALL
CHAIN)
(Escherichia
coli) 		4 / 7 VAL B1695
GLY B1735
THR B1761
ILE B1736
 None
 0.88A 1gtnC-1a9xB:
undetectable
1gtnD-1a9xB:
undetectable		 1gtnC-1a9xB:
10.94
1gtnD-1a9xB:
10.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OS6_A_DXCA75_0
(PPCA)		 1a9x CARBAMOYL PHOSPHATE
SYNTHETASE (SMALL
CHAIN)
(Escherichia
coli) 		4 / 8 ILE B1705
LEU B1709
PHE B1870
GLY B1735
 None
 0.98A 1os6A-1a9xB:
undetectable		 1os6A-1a9xB:
12.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Y7I_A_SALA501_1
(SALICYLIC
ACID-BINDING PROTEIN
2)		 1a9x CARBAMOYL PHOSPHATE
SYNTHETASE (SMALL
CHAIN)
(Escherichia
coli) 		5 / 9 GLY B1521
ALA B1609
SER B1599
LEU B1602
LEU B1543
 None
 1.26A 1y7iA-1a9xB:
3.1		 1y7iA-1a9xB:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AOJ_C_FRDC305_2
(POL POLYPROTEIN
PEPTIDE INHIBITOR)		 1a9x CARBAMOYL PHOSPHATE
SYNTHETASE (SMALL
CHAIN)
(Escherichia
coli) 		4 / 7 LEU B1555
GLY B1521
ILE B1607
ILE B1582
 None
 0.67A 2aojB-1a9xB:
0.0		 2aojB-1a9xB:
14.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYS_C_CHDC304_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1a9x CARBAMOYL PHOSPHATE
SYNTHETASE (SMALL
CHAIN)
(Escherichia
coli) 		4 / 6 HIS B1812
ASP B1862
THR B1808
HIS B1772
 CYG  B1769 ( 4.9A)
None
None
CYG  B1769 ( 4.9A)
 1.28A 2dysA-1a9xB:
undetectable
2dysC-1a9xB:
undetectable		 2dysA-1a9xB:
20.72
2dysC-1a9xB:
19.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIL_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1a9x CARBAMOYL PHOSPHATE
SYNTHETASE (SMALL
CHAIN)
(Escherichia
coli) 		4 / 7 HIS B1812
ASP B1862
THR B1808
HIS B1772
 CYG  B1769 ( 4.9A)
None
None
CYG  B1769 ( 4.9A)
 1.27A 2eilA-1a9xB:
undetectable
2eilC-1a9xB:
undetectable		 2eilA-1a9xB:
20.72
2eilC-1a9xB:
19.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIM_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1a9x CARBAMOYL PHOSPHATE
SYNTHETASE (SMALL
CHAIN)
(Escherichia
coli) 		4 / 6 HIS B1812
ASP B1862
THR B1808
HIS B1772
 CYG  B1769 ( 4.9A)
None
None
CYG  B1769 ( 4.9A)
 1.22A 2eimN-1a9xB:
undetectable
2eimP-1a9xB:
undetectable		 2eimN-1a9xB:
20.72
2eimP-1a9xB:
19.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QO6_A_CHDA130_0
(LIVER-BASIC FATTY
ACID BINDING PROTEIN)		 1a9x CARBAMOYL PHOSPHATE
SYNTHETASE (SMALL
CHAIN)
(Escherichia
coli) 		5 / 12 TYR B1750
ILE B1755
LEU B1774
ALA B1659
PHE B1758
 None
 1.25A 2qo6A-1a9xB:
undetectable		 2qo6A-1a9xB:
16.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2R2V_D_ACTD36_0
(GCN4 LEUCINE ZIPPER)		 1a9x CARBAMOYL PHOSPHATE
SYNTHETASE (SMALL
CHAIN)
(Escherichia
coli) 		3 / 3 SER B1547
TYR B1548
HIS B1576
 CYG  B1769 (-3.2A)
None
None
 0.67A 2r2vD-1a9xB:
0.0		 2r2vD-1a9xB:
6.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2UXP_A_CLMA1211_0
(HTH-TYPE
TRANSCRIPTIONAL
REGULATOR TTGR)		 1a9x CARBAMOYL PHOSPHATE
SYNTHETASE (SMALL
CHAIN)
(Escherichia
coli) 		5 / 8 ALA B1627
GLU B1529
LEU B1622
LEU B1618
ILE B1552
 None
 1.34A 2uxpA-1a9xB:
undetectable		 2uxpA-1a9xB:
19.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XZ5_D_ACHD1211_0
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)		 1a9x CARBAMOYL PHOSPHATE
SYNTHETASE (SMALL
CHAIN)
(Escherichia
coli) 		4 / 8 GLN B1574
GLN B1551
ASP B1545
SER B1547
 None
None
None
CYG  B1769 (-3.2A)
 1.23A 2xz5C-1a9xB:
0.0
2xz5D-1a9xB:
0.0		 2xz5C-1a9xB:
19.74
2xz5D-1a9xB:
19.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZJ0_B_2FAB500_1
(ADENOSYLHOMOCYSTEINA
SE)		 1a9x CARBAMOYL PHOSPHATE
SYNTHETASE (SMALL
CHAIN)
(Escherichia
coli) 		5 / 12 HIS B1829
ASP B1799
GLU B1801
LEU B1866
HIS B1841
 None
 1.13A 2zj0B-1a9xB:
3.1		 2zj0B-1a9xB:
24.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZM9_A_ACAA502_1
(6-AMINOHEXANOATE-DIM
ER HYDROLASE)		 1a9x CARBAMOYL PHOSPHATE
SYNTHETASE (SMALL
CHAIN)
(Escherichia
coli) 		4 / 8 ALA B1577
HIS B1576
GLY B1579
ILE B1607
 None
 0.83A 2zm9A-1a9xB:
0.0		 2zm9A-1a9xB:
21.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZZN_B_SAMB402_0
(UNCHARACTERIZED
PROTEIN MJ0883)		 1a9x CARBAMOYL PHOSPHATE
SYNTHETASE (SMALL
CHAIN)
(Escherichia
coli) 		5 / 12 LEU B1837
GLY B1852
ILE B1705
ASN B1740
PHE B1870
 None
None
None
CYG  B1769 ( 4.6A)
None
 1.43A 2zznB-1a9xB:
undetectable		 2zznB-1a9xB:
21.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AVP_A_MV2A313_1
(PANTOTHENATE KINASE)		 1a9x CARBAMOYL PHOSPHATE
SYNTHETASE (SMALL
CHAIN)
(Escherichia
coli) 		4 / 7 VAL B1530
ASP B1511
LEU B1622
ILE B1610
 None
 0.92A 3avpA-1a9xB:
undetectable		 3avpA-1a9xB:
21.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AX9_B_SALB1340_1
(XANTHINE
DEHYDROGENASE/OXIDAS
E)		 1a9x CARBAMOYL PHOSPHATE
SYNTHETASE (SMALL
CHAIN)
(Escherichia
coli) 		4 / 8 ARG B1712
PHE B1867
ALA B1863
ALA B1864
 None
 0.84A 3ax9B-1a9xB:
0.0		 3ax9B-1a9xB:
15.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CE6_B_ADNB500_1
(ADENOSYLHOMOCYSTEINA
SE)		 1a9x CARBAMOYL PHOSPHATE
SYNTHETASE (SMALL
CHAIN)
(Escherichia
coli) 		5 / 12 HIS B1829
ASP B1799
GLU B1801
LEU B1866
HIS B1841
 None
 1.08A 3ce6B-1a9xB:
3.7		 3ce6B-1a9xB:
24.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ELZ_A_CHDA150_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 1a9x CARBAMOYL PHOSPHATE
SYNTHETASE (SMALL
CHAIN)
(Escherichia
coli) 		5 / 12 PHE B1737
THR B1663
VAL B1662
LEU B1709
TYR B1668
 None
 1.37A 3elzA-1a9xB:
undetectable		 3elzA-1a9xB:
17.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EM4_A_DR7A100_1
(PROTEASE)		 1a9x CARBAMOYL PHOSPHATE
SYNTHETASE (SMALL
CHAIN)
(Escherichia
coli) 		5 / 11 GLY B1700
ALA B1701
ILE B1768
GLY B1771
LEU B1774
 None
None
CYG  B1769 ( 3.8A)
CYG  B1769 ( 4.1A)
None
 0.94A 3em4A-1a9xB:
undetectable		 3em4A-1a9xB:
14.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NS1_C_PM6C1_1
(XANTHINE
DEHYDROGENASE/OXIDAS
E)		 1a9x CARBAMOYL PHOSPHATE
SYNTHETASE (SMALL
CHAIN)
(Escherichia
coli) 		4 / 6 ARG B1712
PHE B1867
ALA B1863
ALA B1864
 None
 0.86A 3ns1C-1a9xB:
0.0		 3ns1C-1a9xB:
20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NS1_L_PM6L1_1
(XANTHINE
DEHYDROGENASE/OXIDAS
E)		 1a9x CARBAMOYL PHOSPHATE
SYNTHETASE (SMALL
CHAIN)
(Escherichia
coli) 		4 / 8 ARG B1712
PHE B1867
ALA B1863
ALA B1864
 None
 0.86A 3ns1L-1a9xB:
undetectable		 3ns1L-1a9xB:
20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SEL_X_DXCX75_0
(CYTOCHROME C7)		 1a9x CARBAMOYL PHOSPHATE
SYNTHETASE (SMALL
CHAIN)
(Escherichia
coli) 		4 / 8 ILE B1705
LEU B1709
PHE B1870
GLY B1735
 None
 0.97A 3selX-1a9xB:
undetectable		 3selX-1a9xB:
13.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SJ1_X_DXCX75_0
(CYTOCHROME C7)		 1a9x CARBAMOYL PHOSPHATE
SYNTHETASE (SMALL
CHAIN)
(Escherichia
coli) 		4 / 6 ILE B1705
LEU B1709
PHE B1870
GLY B1735
 None
 0.99A 3sj1X-1a9xB:
0.0		 3sj1X-1a9xB:
12.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AZS_A_SAMA1475_0
(METHYLTRANSFERASE
WBDD)		 1a9x CARBAMOYL PHOSPHATE
SYNTHETASE (SMALL
CHAIN)
(Escherichia
coli) 		5 / 12 GLY B1579
ALA B1577
ILE B1632
LEU B1602
VAL B1608
 None
 1.24A 4azsA-1a9xB:
undetectable		 4azsA-1a9xB:
21.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AZW_A_SAMA1451_0
(WBDD)		 1a9x CARBAMOYL PHOSPHATE
SYNTHETASE (SMALL
CHAIN)
(Escherichia
coli) 		5 / 12 GLY B1579
ALA B1577
ILE B1632
LEU B1602
VAL B1608
 None
 1.22A 4azwA-1a9xB:
undetectable		 4azwA-1a9xB:
22.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BLV_A_SAMA1281_1
(RIBOSOMAL RNA LARGE
SUBUNIT
METHYLTRANSFERASE J)		 1a9x CARBAMOYL PHOSPHATE
SYNTHETASE (SMALL
CHAIN)
(Escherichia
coli) 		4 / 6 HIS B1795
SER B1831
GLU B1818
ASP B1834
 None
 1.36A 4blvA-1a9xB:
2.2		 4blvA-1a9xB:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DO3_B_0LAB602_1
(FATTY-ACID AMIDE
HYDROLASE 1)		 1a9x CARBAMOYL PHOSPHATE
SYNTHETASE (SMALL
CHAIN)
(Escherichia
coli) 		4 / 6 LEU B1770
LEU B1774
ILE B1752
THR B1783
 CYG  B1769 ( 4.1A)
None
None
None
 0.65A 4do3B-1a9xB:
2.3		 4do3B-1a9xB:
22.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HAJ_A_DXCA75_0
(PPCA)		 1a9x CARBAMOYL PHOSPHATE
SYNTHETASE (SMALL
CHAIN)
(Escherichia
coli) 		4 / 7 ILE B1705
LEU B1709
PHE B1870
GLY B1735
 None
 0.97A 4hajA-1a9xB:
undetectable		 4hajA-1a9xB:
12.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HBF_A_DXCA75_0
(PPCA)		 1a9x CARBAMOYL PHOSPHATE
SYNTHETASE (SMALL
CHAIN)
(Escherichia
coli) 		4 / 7 ILE B1705
LEU B1709
PHE B1870
GLY B1735
 None
 0.91A 4hbfA-1a9xB:
0.0		 4hbfA-1a9xB:
13.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HC3_A_DXCA75_0
(PPCA)		 1a9x CARBAMOYL PHOSPHATE
SYNTHETASE (SMALL
CHAIN)
(Escherichia
coli) 		4 / 7 ILE B1705
LEU B1709
PHE B1870
GLY B1735
 None
 0.95A 4hc3A-1a9xB:
undetectable		 4hc3A-1a9xB:
12.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LMN_A_EUIA503_2
(DUAL SPECIFICITY
MITOGEN-ACTIVATED
PROTEIN KINASE
KINASE 1)		 1a9x CARBAMOYL PHOSPHATE
SYNTHETASE (SMALL
CHAIN)
(Escherichia
coli) 		3 / 3 ASP B1584
VAL B1581
ASN B1562
 None
 0.79A 4lmnA-1a9xB:
0.0		 4lmnA-1a9xB:
23.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MMD_B_29EB603_1
(TRANSPORTER)		 1a9x CARBAMOYL PHOSPHATE
SYNTHETASE (SMALL
CHAIN)
(Escherichia
coli) 		5 / 12 ASP B1698
PRO B1745
TYR B1750
SER B1739
GLY B1771
 None
None
None
None
CYG  B1769 ( 4.1A)
 1.11A 4mmdB-1a9xB:
undetectable		 4mmdB-1a9xB:
22.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NED_A_PFNA709_1
(LACTOTRANSFERRIN)		 1a9x CARBAMOYL PHOSPHATE
SYNTHETASE (SMALL
CHAIN)
(Escherichia
coli) 		4 / 6 ASP B1657
VAL B1662
SER B1739
ALA B1751
 None
 0.96A 4nedA-1a9xB:
0.3		 4nedA-1a9xB:
22.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O8F_A_BRLA501_2
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 1a9x CARBAMOYL PHOSPHATE
SYNTHETASE (SMALL
CHAIN)
(Escherichia
coli) 		4 / 5 GLY B1579
LEU B1618
ILE B1610
LEU B1653
 None
 0.82A 4o8fA-1a9xB:
0.0		 4o8fA-1a9xB:
22.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X20_D_LOCD502_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		 1a9x CARBAMOYL PHOSPHATE
SYNTHETASE (SMALL
CHAIN)
(Escherichia
coli) 		3 / 3 SER B1739
ALA B1696
VAL B1695
 None
 0.61A 4x20C-1a9xB:
undetectable		 4x20C-1a9xB:
23.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FCT_A_C2FA402_0
(THYMIDYLATE SYNTHASE)		 1a9x CARBAMOYL PHOSPHATE
SYNTHETASE (SMALL
CHAIN)
(Escherichia
coli) 		5 / 11 PHE B1814
LEU B1825
LEU B1774
GLY B1771
ALA B1778
 CYG  B1769 (-4.8A)
None
None
CYG  B1769 ( 4.1A)
None
 1.35A 5fctA-1a9xB:
0.0		 5fctA-1a9xB:
21.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OGJ_B_ACTB305_0
(CARBONIC ANHYDRASE
13)		 1a9x CARBAMOYL PHOSPHATE
SYNTHETASE (SMALL
CHAIN)
(Escherichia
coli) 		4 / 6 HIS B1812
HIS B1790
LEU B1837
THR B1836
 CYG  B1769 ( 4.9A)
None
None
None
 1.16A 5ogjB-1a9xB:
undetectable		 5ogjB-1a9xB:
22.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OHH_A_ACTA307_0
(CARBONIC ANHYDRASE
13)		 1a9x CARBAMOYL PHOSPHATE
SYNTHETASE (SMALL
CHAIN)
(Escherichia
coli) 		4 / 5 HIS B1812
HIS B1790
LEU B1837
THR B1836
 CYG  B1769 ( 4.9A)
None
None
None
 1.15A 5ohhA-1a9xB:
undetectable		 5ohhA-1a9xB:
22.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OHH_B_ACTB311_0
(CARBONIC ANHYDRASE
13)		 1a9x CARBAMOYL PHOSPHATE
SYNTHETASE (SMALL
CHAIN)
(Escherichia
coli) 		4 / 6 HIS B1812
HIS B1790
LEU B1837
THR B1836
 CYG  B1769 ( 4.9A)
None
None
None
 1.15A 5ohhB-1a9xB:
undetectable		 5ohhB-1a9xB:
22.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UTU_H_ADNH503_2
(ADENOSYLHOMOCYSTEINA
SE)		 1a9x CARBAMOYL PHOSPHATE
SYNTHETASE (SMALL
CHAIN)
(Escherichia
coli) 		4 / 5 THR B1565
GLU B1541
HIS B1791
LEU B1555
 None
 1.12A 5utuH-1a9xB:
2.4		 5utuH-1a9xB:
23.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GNF_A_QPSA602_2
(-)		 1a9x CARBAMOYL PHOSPHATE
SYNTHETASE (SMALL
CHAIN)
(Escherichia
coli) 		5 / 9 GLY B1793
GLY B1792
HIS B1791
VAL B1531
GLU B1541
 None
 1.35A 6gnfA-1a9xB:
2.9		 6gnfA-1a9xB:
20.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6R2E_F_FFOF403_0
(THYMIDYLATE SYNTHASE)		 1a9x CARBAMOYL PHOSPHATE
SYNTHETASE (SMALL
CHAIN)
(Escherichia
coli) 		5 / 11 PHE B1814
LEU B1825
LEU B1774
GLY B1771
ALA B1778
 CYG  B1769 (-4.8A)
None
None
CYG  B1769 ( 4.1A)
None
 1.30A 6r2eF-1a9xB:
0.0		 6r2eF-1a9xB:
21.07