SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1aa0'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GRM_A_DVAA6_0
(GRAMICIDIN A)		 1aa0 FIBRITIN
(Escherichia
virus
T4) 		3 / 3 ALA A 468
VAL A 477
TRP A 476
 None
 0.87A 1grmA-1aa0A:
undetectable		 1grmA-1aa0A:
8.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GRM_B_DVAB6_0
(GRAMICIDIN A)		 1aa0 FIBRITIN
(Escherichia
virus
T4) 		3 / 3 ALA A 468
VAL A 477
TRP A 476
 None
 0.87A 1grmB-1aa0A:
undetectable		 1grmB-1aa0A:
8.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AC9_C_DXCC1479_0
(MJ0495-LIKE PROTEIN)		 1aa0 FIBRITIN
(Escherichia
virus
T4) 		4 / 5 THR A 419
ILE A 422
LYS A 423
GLU A 426
 None
CL  A 484 ( 4.5A)
None
None
 0.49A 4ac9C-1aa0A:
undetectable		 4ac9C-1aa0A:
14.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ACA_C_DXCC1479_0
(TRANSLATION
ELONGATION FACTOR
SELB)		 1aa0 FIBRITIN
(Escherichia
virus
T4) 		4 / 5 THR A 419
ILE A 422
LYS A 423
GLU A 426
 None
CL  A 484 ( 4.5A)
None
None
 0.48A 4acaC-1aa0A:
undetectable		 4acaC-1aa0A:
14.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ACB_C_DXCC1479_0
(TRANSLATION
ELONGATION FACTOR
SELB)		 1aa0 FIBRITIN
(Escherichia
virus
T4) 		4 / 5 THR A 419
ILE A 422
LYS A 423
GLU A 426
 None
CL  A 484 ( 4.5A)
None
None
 0.55A 4acbC-1aa0A:
undetectable		 4acbC-1aa0A:
14.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FGD_A_ACTA819_0
(GEPHYRIN)		 1aa0 FIBRITIN
(Escherichia
virus
T4) 		3 / 3 ARG A 471
GLY A 474
GLU A 475
 None
None
ZN  A 565 (-1.3A)
 0.62A 6fgdA-1aa0A:
undetectable		 6fgdA-1aa0A:
14.56