SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1aa2'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K8M_B_ACRB820_1
(ALPHA-AMYLASE, SUSG)		 1aa2 BETA-SPECTRIN
(Homo
sapiens) 		4 / 7 GLU A  92
TRP A  31
LEU A  40
TRP A  11
 None
 1.42A 3k8mB-1aa2A:
undetectable		 3k8mB-1aa2A:
11.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KK6_A_CELA701_2
(PROSTAGLANDIN G/H
SYNTHASE 1)		 1aa2 BETA-SPECTRIN
(Homo
sapiens) 		4 / 6 VAL A  99
SER A  30
LEU A  54
LEU A  40
 None
 0.99A 3kk6A-1aa2A:
undetectable		 3kk6A-1aa2A:
11.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZJZ_B_BEZB601_0
(BENZOATE-COENZYME A
LIGASE)		 1aa2 BETA-SPECTRIN
(Homo
sapiens) 		5 / 8 ALA A  39
VAL A  22
PHE A  51
ALA A  66
GLY A  34
 None
 1.30A 4zjzB-1aa2A:
undetectable		 4zjzB-1aa2A:
11.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0O_A_SAMA501_1
(PEPTIDE
N-METHYLTRANSFERASE)		 1aa2 BETA-SPECTRIN
(Homo
sapiens) 		3 / 3 ALA A  36
GLN A  13
THR A  16
 None
 0.71A 5n0oA-1aa2A:
undetectable		 5n0oA-1aa2A:
13.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZMQ_K_PACK1_0
(SERINE PROTEASE NS3
PEPTIDE
PAC-DLY-DLY-DAR)		 1aa2 BETA-SPECTRIN
(Homo
sapiens) 		3 / 3 ALA A  39
VAL A  99
TYR A 102
 None
 0.60A 5zmqH-1aa2A:
undetectable		 5zmqH-1aa2A:
24.28