SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1ab6'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)	View	Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3JW5_A_TOPA208_1 (DIHYDROFOLATE REDUCTASE)	1ab6	CHEMOTAXIS PROTEIN CHEY (Escherichia coli)	5 / 11	ASN A 121 LEU A 120 LEU A 25 VAL A 21 PHE A 111	None	1.24A	3jw5A-1ab6A: undetectable	3jw5A-1ab6A: 20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3ZQT_A_30ZA1920_1 (ANDROGEN RECEPTOR)	1ab6	CHEMOTAXIS PROTEIN CHEY (Escherichia coli)	4 / 6	GLY A 52 LEU A 6 ASN A 32 GLU A 34	None	0.97A	3zqtA-1ab6A: undetectable	3zqtA-1ab6A: 17.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4M2V_A_BZ1A302_1 (CARBONIC ANHYDRASE 2)	1ab6	CHEMOTAXIS PROTEIN CHEY (Escherichia coli)	5 / 12	LEU A 9 VAL A 54 GLY A 49 VAL A 83 THR A 71	None	0.93A	4m2vA-1ab6A: undetectable	4m2vA-1ab6A: 18.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4M2W_A_ETSA302_1 (CARBONIC ANHYDRASE 2)	1ab6	CHEMOTAXIS PROTEIN CHEY (Escherichia coli)	5 / 12	LEU A 9 VAL A 54 LEU A 81 VAL A 83 THR A 71	None	0.95A	4m2wA-1ab6A: undetectable	4m2wA-1ab6A: 18.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5IK1_A_CAMA503_0 (CAMPHOR 5-MONOOXYGENASE)	1ab6	CHEMOTAXIS PROTEIN CHEY (Escherichia coli)	4 / 7	GLY A 39 VAL A 83 ILE A 55 VAL A 54	None	0.79A	5ik1A-1ab6A: undetectable	5ik1A-1ab6A: 15.76

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["3JW5_A_TOPA208_1","DIHYDROFOLATE REDUCTASE","1ab6","CHEMOTAXIS PROTEIN CHEY","Escherichia coli",5,"ASN A 121;LEU A 120;LEU A  25;VAL A  21;PHE A 111","None","1.24A","3jw5A-1ab6A:undetectable","3jw5A-1ab6A:20.00"],["3ZQT_A_30ZA1920_1","ANDROGEN RECEPTOR","1ab6","CHEMOTAXIS PROTEIN CHEY","Escherichia coli",4,"GLY A  52;LEU A   6;ASN A  32;GLU A  34","None","0.97A","3zqtA-1ab6A:undetectable","3zqtA-1ab6A:17.27"],["4M2V_A_BZ1A302_1","CARBONIC ANHYDRASE 2","1ab6","CHEMOTAXIS PROTEIN CHEY","Escherichia coli",5,"LEU A   9;VAL A  54;GLY A  49;VAL A  83;THR A  71","None","0.93A","4m2vA-1ab6A:undetectable","4m2vA-1ab6A:18.75"],["4M2W_A_ETSA302_1","CARBONIC ANHYDRASE 2","1ab6","CHEMOTAXIS PROTEIN CHEY","Escherichia coli",5,"LEU A   9;VAL A  54;LEU A  81;VAL A  83;THR A  71","None","0.95A","4m2wA-1ab6A:undetectable","4m2wA-1ab6A:18.75"],["5IK1_A_CAMA503_0","CAMPHOR 5-MONOOXYGENASE","1ab6","CHEMOTAXIS PROTEIN CHEY","Escherichia coli",4,"GLY A  39;VAL A  83;ILE A  55;VAL A  54","None","0.79A","5ik1A-1ab6A:undetectable","5ik1A-1ab6A:15.76"]]