SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1ac5'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IG3_A_VIBA502_1
(THIAMIN
PYROPHOSPHOKINASE)		 1ac5 KEX1(DELTA)P
(Saccharomyces
cerevisiae) 		4 / 8 LEU A 222
SER A 257
ASN A 256
THR A 260
 None
 1.12A 1ig3A-1ac5A:
0.0
1ig3B-1ac5A:
2.1		 1ig3A-1ac5A:
19.43
1ig3B-1ac5A:
19.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MAA_D_DMED999_1
(ACETYLCHOLINESTERASE)		 1ac5 KEX1(DELTA)P
(Saccharomyces
cerevisiae) 		4 / 8 GLY A  76
GLU A 175
SER A 176
HIS A 448
 None
 0.86A 1maaD-1ac5A:
3.4		 1maaD-1ac5A:
21.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QTI_A_GNTA600_1
(ACETYLCHOLINESTERASE)		 1ac5 KEX1(DELTA)P
(Saccharomyces
cerevisiae) 		5 / 12 GLY A  75
GLY A  76
GLU A 175
SER A 176
HIS A 448
 None
 0.83A 1qtiA-1ac5A:
11.8		 1qtiA-1ac5A:
22.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WRL_B_TFPB203_1
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		 1ac5 KEX1(DELTA)P
(Saccharomyces
cerevisiae) 		4 / 6 PHE A 322
VAL A 328
LEU A 332
SER A  80
 None
 1.01A 1wrlB-1ac5A:
undetectable		 1wrlB-1ac5A:
11.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YAJ_C_BEZC5013_0
(CES1 PROTEIN)		 1ac5 KEX1(DELTA)P
(Saccharomyces
cerevisiae) 		5 / 8 GLY A  75
GLY A  76
SER A 176
ILE A 385
HIS A 448
 None
 0.82A 1yajC-1ac5A:
10.9		 1yajC-1ac5A:
19.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YAJ_F_BEZF5023_0
(CES1 PROTEIN)		 1ac5 KEX1(DELTA)P
(Saccharomyces
cerevisiae) 		4 / 6 GLY A  76
SER A 176
ILE A 385
HIS A 448
 None
 0.89A 1yajF-1ac5A:
10.8		 1yajF-1ac5A:
19.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YAJ_J_BEZJ5041_0
(CES1 PROTEIN)		 1ac5 KEX1(DELTA)P
(Saccharomyces
cerevisiae) 		4 / 4 GLY A  75
SER A 176
ILE A 385
HIS A 448
 None
 1.37A 1yajJ-1ac5A:
9.3		 1yajJ-1ac5A:
19.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YAJ_J_BEZJ5041_0
(CES1 PROTEIN)		 1ac5 KEX1(DELTA)P
(Saccharomyces
cerevisiae) 		4 / 4 GLY A  76
SER A 176
ILE A 385
HIS A 448
 None
 0.84A 1yajJ-1ac5A:
9.3		 1yajJ-1ac5A:
19.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YNN_C_RFPC1120_1
(DNA-DIRECTED RNA
POLYMERASE BETA
CHAIN)		 1ac5 KEX1(DELTA)P
(Saccharomyces
cerevisiae) 		5 / 12 ARG A  93
SER A 173
LEU A 209
PRO A  68
ILE A  70
 None
 1.17A 1ynnC-1ac5A:
0.0		 1ynnC-1ac5A:
17.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2H42_C_VIAC903_2
(CGMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE)		 1ac5 KEX1(DELTA)P
(Saccharomyces
cerevisiae) 		3 / 3 ASN A 103
ILE A  26
MET A  29
 None
 0.80A 2h42C-1ac5A:
0.0		 2h42C-1ac5A:
21.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HKK_A_ALEA300_1
(CARBONIC ANHYDRASE 2)		 1ac5 KEX1(DELTA)P
(Saccharomyces
cerevisiae) 		4 / 6 ASN A 212
HIS A 448
ASN A 379
ILE A 395
 None
 1.23A 2hkkA-1ac5A:
undetectable		 2hkkA-1ac5A:
19.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OTF_A_2TNA201_1
(PHOSPHOLIPASE A2
VRV-PL-VIIIA)		 1ac5 KEX1(DELTA)P
(Saccharomyces
cerevisiae) 		4 / 5 ILE A 108
SER A 106
GLY A 105
HIS A 417
 None
 0.83A 2otfA-1ac5A:
undetectable		 2otfA-1ac5A:
15.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WEK_A_DIFA1373_1
(ZINC-BINDING ALCOHOL
DEHYDROGENASE
DOMAIN-CONTAINING
PROTEIN 2)		 1ac5 KEX1(DELTA)P
(Saccharomyces
cerevisiae) 		4 / 8 ASN A 379
SER A 442
VAL A 391
TYR A 444
 None
None
None
NAG  A 900 ( 3.1A)
 1.14A 2wekA-1ac5A:
2.9		 2wekA-1ac5A:
20.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WEK_B_DIFB1373_1
(ZINC-BINDING ALCOHOL
DEHYDROGENASE
DOMAIN-CONTAINING
PROTEIN 2)		 1ac5 KEX1(DELTA)P
(Saccharomyces
cerevisiae) 		4 / 8 ASN A 379
SER A 442
VAL A 391
TYR A 444
 None
None
None
NAG  A 900 ( 3.1A)
 1.14A 2wekB-1ac5A:
undetectable		 2wekB-1ac5A:
20.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIA_A_SAMA206_0
(UPF0217 PROTEIN
MJ1640)		 1ac5 KEX1(DELTA)P
(Saccharomyces
cerevisiae) 		4 / 6 LEU A 100
GLY A  98
LEU A  17
SER A  18
 None
 0.82A 3aiaA-1ac5A:
1.7		 3aiaA-1ac5A:
18.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ELZ_A_CHDA150_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 1ac5 KEX1(DELTA)P
(Saccharomyces
cerevisiae) 		5 / 12 PHE A 323
THR A 346
VAL A 319
LEU A  86
ILE A 316
 None
 1.34A 3elzA-1ac5A:
undetectable		 3elzA-1ac5A:
14.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3F78_A_ICFA1_1
(INTEGRIN ALPHA-L)		 1ac5 KEX1(DELTA)P
(Saccharomyces
cerevisiae) 		5 / 9 ILE A  34
ILE A 161
LYS A 160
LEU A   1
GLU A  39
 None
 1.48A 3f78A-1ac5A:
1.8		 3f78A-1ac5A:
19.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G1U_A_ADNA438_1
(ADENOSYLHOMOCYSTEINA
SE)		 1ac5 KEX1(DELTA)P
(Saccharomyces
cerevisiae) 		5 / 12 HIS A 150
ASP A 141
LEU A  49
LEU A  36
PHE A 185
 None
 1.24A 3g1uA-1ac5A:
undetectable		 3g1uA-1ac5A:
20.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G1U_B_ADNB438_1
(ADENOSYLHOMOCYSTEINA
SE)		 1ac5 KEX1(DELTA)P
(Saccharomyces
cerevisiae) 		5 / 12 HIS A 150
ASP A 141
LEU A  49
LEU A  36
PHE A 185
 None
 1.27A 3g1uB-1ac5A:
undetectable		 3g1uB-1ac5A:
20.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G1U_C_ADNC438_1
(ADENOSYLHOMOCYSTEINA
SE)		 1ac5 KEX1(DELTA)P
(Saccharomyces
cerevisiae) 		5 / 12 HIS A 150
ASP A 141
LEU A  49
LEU A  36
PHE A 185
 None
 1.30A 3g1uC-1ac5A:
4.1		 3g1uC-1ac5A:
20.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G1U_D_ADND438_1
(ADENOSYLHOMOCYSTEINA
SE)		 1ac5 KEX1(DELTA)P
(Saccharomyces
cerevisiae) 		5 / 12 HIS A 150
ASP A 141
LEU A  49
LEU A  36
PHE A 185
 None
 1.24A 3g1uD-1ac5A:
2.6		 3g1uD-1ac5A:
20.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3I9J_B_NCAB302_0
(ADP-RIBOSYL CYCLASE)		 1ac5 KEX1(DELTA)P
(Saccharomyces
cerevisiae) 		4 / 6 GLU A 175
ASN A  74
SER A 447
PHE A 452
 None
 1.34A 3i9jB-1ac5A:
undetectable		 3i9jB-1ac5A:
19.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_J_TFPJ202_1
(PROTEIN S100-A4)		 1ac5 KEX1(DELTA)P
(Saccharomyces
cerevisiae) 		5 / 11 PHE A 159
LEU A 205
ASP A 204
LEU A 172
ILE A 189
 None
 1.29A 3ko0A-1ac5A:
undetectable
3ko0B-1ac5A:
0.0
3ko0I-1ac5A:
0.0
3ko0J-1ac5A:
0.0		 3ko0A-1ac5A:
13.14
3ko0B-1ac5A:
13.14
3ko0I-1ac5A:
13.14
3ko0J-1ac5A:
13.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N58_A_ADNA500_1
(ADENOSYLHOMOCYSTEINA
SE)		 1ac5 KEX1(DELTA)P
(Saccharomyces
cerevisiae) 		5 / 12 HIS A 150
ASP A 141
LEU A  49
LEU A  36
PHE A 185
 None
 1.26A 3n58A-1ac5A:
4.4		 3n58A-1ac5A:
20.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N58_C_ADNC500_1
(ADENOSYLHOMOCYSTEINA
SE)		 1ac5 KEX1(DELTA)P
(Saccharomyces
cerevisiae) 		5 / 12 HIS A 150
ASP A 141
LEU A  49
LEU A  36
PHE A 185
 None
 1.27A 3n58C-1ac5A:
4.3		 3n58C-1ac5A:
20.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SUE_D_SUED1201_1
(NS3 PROTEASE, NS4A
PROTEIN)		 1ac5 KEX1(DELTA)P
(Saccharomyces
cerevisiae) 		5 / 12 HIS A 448
ASP A 383
GLY A  75
SER A 176
SER A  89
 None
 1.21A 3sueD-1ac5A:
undetectable		 3sueD-1ac5A:
17.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BUP_B_SAMB500_1
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SUV420H1)		 1ac5 KEX1(DELTA)P
(Saccharomyces
cerevisiae) 		3 / 3 HIS A 448
GLU A  88
ASN A  74
 None
 0.94A 4bupB-1ac5A:
0.0		 4bupB-1ac5A:
21.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C5N_C_PXLC300_1
(PHOSPHOMETHYLPYRIMID
INE KINASE)		 1ac5 KEX1(DELTA)P
(Saccharomyces
cerevisiae) 		4 / 8 ASP A 463
GLY A 460
VAL A 469
VAL A 441
 None
 0.85A 4c5nC-1ac5A:
3.0		 4c5nC-1ac5A:
19.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EIX_A_NIMA201_1
(PHOSPHOLIPASE A2
VRV-PL-VIIIA)		 1ac5 KEX1(DELTA)P
(Saccharomyces
cerevisiae) 		4 / 4 LEU A 294
ALA A 228
ILE A 234
LYS A 302
 None
 1.39A 4eixA-1ac5A:
0.0		 4eixA-1ac5A:
15.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KTT_A_SAMA405_0
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)		 1ac5 KEX1(DELTA)P
(Saccharomyces
cerevisiae) 		4 / 8 HIS A 417
SER A 455
SER A  89
ASP A 463
 None
 1.19A 4kttA-1ac5A:
undetectable		 4kttA-1ac5A:
21.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MJW_A_ACTA603_0
(CHOLINE OXIDASE)		 1ac5 KEX1(DELTA)P
(Saccharomyces
cerevisiae) 		3 / 3 ARG A 459
HIS A 417
SER A 455
 None
 1.03A 4mjwA-1ac5A:
0.0
4mjwB-1ac5A:
1.3		 4mjwA-1ac5A:
22.22
4mjwB-1ac5A:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MJW_B_ACTB603_0
(CHOLINE OXIDASE)		 1ac5 KEX1(DELTA)P
(Saccharomyces
cerevisiae) 		3 / 3 SER A 455
ARG A 459
HIS A 417
 None
 1.03A 4mjwA-1ac5A:
0.0
4mjwB-1ac5A:
1.3		 4mjwA-1ac5A:
22.22
4mjwB-1ac5A:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PFJ_B_ADNB502_1
(ADENOSYLHOMOCYSTEINA
SE)		 1ac5 KEX1(DELTA)P
(Saccharomyces
cerevisiae) 		5 / 12 HIS A 150
ASP A 141
LEU A  49
LEU A  36
PHE A 185
 None
 1.31A 4pfjB-1ac5A:
undetectable		 4pfjB-1ac5A:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CCL_A_SAMA504_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SMYD3)		 1ac5 KEX1(DELTA)P
(Saccharomyces
cerevisiae) 		5 / 12 GLY A 211
ASN A 212
GLU A 175
ASN A  74
TYR A 181
 None
 1.36A 5cclA-1ac5A:
undetectable		 5cclA-1ac5A:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E4D_B_BEZB202_0
(HYDROXYNITRILE LYASE)		 1ac5 KEX1(DELTA)P
(Saccharomyces
cerevisiae) 		4 / 7 VAL A 441
THR A 439
VAL A 469
THR A 482
 None
 0.94A 5e4dA-1ac5A:
0.5
5e4dB-1ac5A:
0.5		 5e4dA-1ac5A:
20.10
5e4dB-1ac5A:
20.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E4D_B_BEZB202_0
(HYDROXYNITRILE LYASE)		 1ac5 KEX1(DELTA)P
(Saccharomyces
cerevisiae) 		4 / 7 VAL A 469
THR A 482
VAL A 441
THR A 439
 None
 0.93A 5e4dA-1ac5A:
0.5
5e4dB-1ac5A:
0.5		 5e4dA-1ac5A:
20.10
5e4dB-1ac5A:
20.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HQA_A_ACRA705_2
(ALPHA-GLUCOSIDASE)		 1ac5 KEX1(DELTA)P
(Saccharomyces
cerevisiae) 		4 / 8 TRP A  72
GLU A  88
HIS A 448
THR A 439
 None
 1.46A 5hqaA-1ac5A:
undetectable		 5hqaA-1ac5A:
19.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TE8_A_08JA602_1
(CYTOCHROME P450 3A4)		 1ac5 KEX1(DELTA)P
(Saccharomyces
cerevisiae) 		4 / 7 SER A  89
LEU A 113
ILE A 170
LEU A  69
 None
 1.01A 5te8A-1ac5A:
0.0		 5te8A-1ac5A:
20.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5V37_A_SAMA504_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SMYD3)		 1ac5 KEX1(DELTA)P
(Saccharomyces
cerevisiae) 		5 / 12 GLY A 211
ASN A 212
GLU A 175
ASN A  74
TYR A 181
 None
 1.30A 5v37A-1ac5A:
undetectable		 5v37A-1ac5A:
22.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WBV_A_SAMA402_1
(HISTONE-LYSINE
N-METHYLTRANSFERASE
KMT5B)		 1ac5 KEX1(DELTA)P
(Saccharomyces
cerevisiae) 		3 / 3 HIS A 448
GLU A  88
ASN A  74
 None
 0.91A 5wbvA-1ac5A:
0.0		 5wbvA-1ac5A:
21.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WBV_B_SAMB402_1
(HISTONE-LYSINE
N-METHYLTRANSFERASE
KMT5B)		 1ac5 KEX1(DELTA)P
(Saccharomyces
cerevisiae) 		3 / 3 HIS A 448
GLU A  88
ASN A  74
 None
 0.92A 5wbvB-1ac5A:
0.0		 5wbvB-1ac5A:
21.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XXG_A_SAMA502_0
(SMYD3)		 1ac5 KEX1(DELTA)P
(Saccharomyces
cerevisiae) 		5 / 12 GLY A 211
ASN A 212
GLU A 175
ASN A  74
TYR A 181
 None
 1.31A 5xxgA-1ac5A:
undetectable		 5xxgA-1ac5A:
22.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XXJ_A_SAMA505_0
(SMYD3)		 1ac5 KEX1(DELTA)P
(Saccharomyces
cerevisiae) 		5 / 12 GLY A 211
ASN A 212
GLU A 175
ASN A  74
TYR A 181
 None
 1.31A 5xxjA-1ac5A:
undetectable		 5xxjA-1ac5A:
22.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F3N_A_ADNA505_1
(-)		 1ac5 KEX1(DELTA)P
(Saccharomyces
cerevisiae) 		5 / 12 HIS A 150
ASP A 141
LEU A  49
LEU A  36
PHE A 185
 None
 1.28A 6f3nA-1ac5A:
4.3		 6f3nA-1ac5A:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F3N_C_ADNC505_1
(-)		 1ac5 KEX1(DELTA)P
(Saccharomyces
cerevisiae) 		5 / 12 HIS A 150
ASP A 141
LEU A  49
LEU A  36
PHE A 185
 None
 1.23A 6f3nC-1ac5A:
2.0		 6f3nC-1ac5A:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F3N_D_ADND506_1
(-)		 1ac5 KEX1(DELTA)P
(Saccharomyces
cerevisiae) 		5 / 12 HIS A 150
ASP A 141
LEU A  49
LEU A  36
PHE A 185
 None
 1.28A 6f3nD-1ac5A:
4.3		 6f3nD-1ac5A:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GBN_C_ADNC501_1
(-)		 1ac5 KEX1(DELTA)P
(Saccharomyces
cerevisiae) 		5 / 12 HIS A 150
ASP A 141
LEU A  49
LEU A  36
PHE A 185
 None
 1.21A 6gbnC-1ac5A:
4.3		 6gbnC-1ac5A:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6QXS_D_FOZD403_0
(THYMIDYLATE SYNTHASE)		 1ac5 KEX1(DELTA)P
(Saccharomyces
cerevisiae) 		5 / 12 LEU A 190
LEU A 144
LEU A 172
ILE A 182
ALA A 178
 None
 1.39A 6qxsD-1ac5A:
0.0		 6qxsD-1ac5A:
21.49