SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1ad9'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1USQ_A_CLMA1143_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 1ad9 IGG CTM01 FAB (HEAVY
CHAIN)
(Homo
sapiens) 		5 / 7 GLY H  53
PRO H  52
THR H  57
ILE H  51
GLY H  55
 None
 1.10A 1usqA-1ad9H:
undetectable		 1usqA-1ad9H:
20.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1USQ_B_CLMB1143_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 1ad9 IGG CTM01 FAB (HEAVY
CHAIN)
(Homo
sapiens) 		4 / 6 GLY H  53
PRO H  52
ILE H  51
GLY H  55
 None
 0.82A 1usqB-1ad9H:
1.0		 1usqB-1ad9H:
20.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1USQ_C_CLMC1143_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 1ad9 IGG CTM01 FAB (HEAVY
CHAIN)
(Homo
sapiens) 		4 / 6 GLY H  53
PRO H  52
ILE H  51
GLY H  55
 None
 0.82A 1usqC-1ad9H:
undetectable		 1usqC-1ad9H:
20.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1USQ_D_CLMD1142_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 1ad9 IGG CTM01 FAB (HEAVY
CHAIN)
(Homo
sapiens) 		4 / 6 GLY H  53
PRO H  52
ILE H  51
GLY H  55
 None
 0.83A 1usqD-1ad9H:
1.0		 1usqD-1ad9H:
20.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1USQ_E_CLME1143_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 1ad9 IGG CTM01 FAB (HEAVY
CHAIN)
(Homo
sapiens) 		4 / 6 GLY H  53
PRO H  52
ILE H  51
GLY H  55
 None
 0.82A 1usqE-1ad9H:
undetectable		 1usqE-1ad9H:
20.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1USQ_F_CLMF1144_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 1ad9 IGG CTM01 FAB (HEAVY
CHAIN)
(Homo
sapiens) 		5 / 7 GLY H  53
PRO H  52
THR H  57
ILE H  51
GLY H  55
 None
 1.09A 1usqF-1ad9H:
undetectable		 1usqF-1ad9H:
20.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AOJ_C_FRDC305_1
(POL POLYPROTEIN
PEPTIDE INHIBITOR)		 1ad9 IGG CTM01 FAB (LIGHT
CHAIN)
(Homo
sapiens) 		4 / 5 LEU L 178
GLY L 127
PRO L 119
VAL L 131
 None
 0.92A 2aojA-1ad9L:
undetectable		 2aojA-1ad9L:
18.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JKJ_E_CLME1141_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 1ad9 IGG CTM01 FAB (HEAVY
CHAIN)
(Homo
sapiens) 		5 / 7 GLY H  53
PRO H  52
THR H  57
ILE H  51
GLY H  55
 None
 1.13A 2jkjE-1ad9H:
1.0		 2jkjE-1ad9H:
20.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JKL_A_CLMA1144_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 1ad9 IGG CTM01 FAB (HEAVY
CHAIN)
(Homo
sapiens) 		5 / 7 GLY H  53
PRO H  52
THR H  57
ILE H  51
GLY H  55
 None
 1.12A 2jklA-1ad9H:
1.0		 2jklA-1ad9H:
20.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JKL_C_CLMC1143_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 1ad9 IGG CTM01 FAB (HEAVY
CHAIN)
(Homo
sapiens) 		5 / 7 GLY H  53
PRO H  52
THR H  57
ILE H  51
GLY H  55
 None
 1.13A 2jklC-1ad9H:
1.0		 2jklC-1ad9H:
20.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JKL_D_CLMD1145_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 1ad9 IGG CTM01 FAB (HEAVY
CHAIN)
(Homo
sapiens) 		5 / 7 GLY H  53
PRO H  52
THR H  57
ILE H  51
GLY H  55
 None
 1.11A 2jklD-1ad9H:
undetectable		 2jklD-1ad9H:
20.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JKL_E_CLME1143_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 1ad9 IGG CTM01 FAB (HEAVY
CHAIN)
(Homo
sapiens) 		5 / 7 GLY H  53
PRO H  52
THR H  57
ILE H  51
GLY H  55
 None
 1.12A 2jklE-1ad9H:
0.0		 2jklE-1ad9H:
20.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JKL_F_CLMF1143_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 1ad9 IGG CTM01 FAB (HEAVY
CHAIN)
(Homo
sapiens) 		5 / 7 GLY H  53
PRO H  52
THR H  57
ILE H  51
GLY H  55
 None
 1.12A 2jklF-1ad9H:
undetectable		 2jklF-1ad9H:
20.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DV1_A_SRYA1601_1
(16S RRNA
RIBOSOMAL PROTEIN
S12)		 1ad9 IGG CTM01 FAB (LIGHT
CHAIN)
(Homo
sapiens) 		3 / 3 LYS L  42
LYS L  39
PRO L  40
 None
 1.11A 4dv1L-1ad9L:
0.5		 4dv1L-1ad9L:
20.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F3T_A_IPHA902_0
(PROTEIN ARGONAUTE-2)		 1ad9 IGG CTM01 FAB (LIGHT
CHAIN)
(Homo
sapiens) 		4 / 6 LEU L  27
LYS L  27
LEU L  92
GLU L  93
 None
 0.74A 4f3tA-1ad9L:
undetectable		 4f3tA-1ad9L:
14.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4W5N_A_IPHA902_0
(PROTEIN ARGONAUTE-2)		 1ad9 IGG CTM01 FAB (LIGHT
CHAIN)
(Homo
sapiens) 		4 / 6 LEU L  27
LYS L  27
LEU L  92
GLU L  93
 None
 0.87A 4w5nA-1ad9L:
undetectable		 4w5nA-1ad9L:
14.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XDT_A_ACTA409_0
(FAD:PROTEIN FMN
TRANSFERASE)		 1ad9 IGG CTM01 FAB (LIGHT
CHAIN)
(Homo
sapiens) 		4 / 5 VAL L  19
ILE L  21
VAL L 104
THR L 102
 None
 0.70A 4xdtA-1ad9L:
0.0		 4xdtA-1ad9L:
20.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CXV_A_0HKA501_2
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M1,ENDOLYSIN,MUSCARI
NIC ACETYLCHOLINE
RECEPTOR M1)		 1ad9 IGG CTM01 FAB (LIGHT
CHAIN)
(Homo
sapiens) 		3 / 3 THR L 102
THR L  85
PHE L  83
 None
 0.80A 5cxvA-1ad9L:
undetectable		 5cxvA-1ad9L:
17.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UMD_A_YMZA3801_1
(60S RIBOSOMAL
PROTEIN L28
28S RIBOSOMAL RNA
60S RIBOSOMAL
PROTEIN L4)		 1ad9 IGG CTM01 FAB (HEAVY
CHAIN)
(Homo
sapiens) 		4 / 6 ASN H  76
ALA H  24
PRO H  52
TYR H  27
 None
 1.05A 5umd2-1ad9H:
0.0
5umdF-1ad9H:
0.0		 5umd2-1ad9H:
17.04
5umdF-1ad9H:
15.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WEA_A_IPHA901_0
(PROTEIN ARGONAUTE-2)		 1ad9 IGG CTM01 FAB (LIGHT
CHAIN)
(Homo
sapiens) 		4 / 5 LEU L  27
LYS L  27
LEU L  92
GLU L  93
 None
 1.18A 5weaA-1ad9L:
undetectable		 5weaA-1ad9L:
14.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDH_C_DAHC60_1
(PUTATIVE CYTOCHROME
C)		 1ad9 IGG CTM01 FAB (HEAVY
CHAIN)
(Homo
sapiens) 		4 / 6 MET H  80
ASN H  76
VAL H  71
LEU H  69
 None
 1.12A 5xdhA-1ad9H:
undetectable
5xdhC-1ad9H:
undetectable		 5xdhA-1ad9H:
16.59
5xdhC-1ad9H:
16.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BPY_A_ACTA408_0
(THIOREDOXIN
REDUCTASE)		 1ad9 IGG CTM01 FAB (HEAVY
CHAIN)
(Homo
sapiens) 		3 / 3 PRO H 185
SER H 187
SER H 188
 None
 0.55A 6bpyA-1ad9H:
0.0		 6bpyA-1ad9H:
21.72