SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1adv'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HO5_B_ADNB2604_1
(5'-NUCLEOTIDASE)		 1adv ADENOVIRUS
SINGLE-STRANDED
DNA-BINDING PROTEIN
(Human
mastadenovirus
C) 		5 / 10 SER A 354
GLY A 356
ARG A 410
ASN A 512
ASP A 342
 None
 1.14A 1ho5B-1advA:
undetectable		 1ho5B-1advA:
20.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UKB_A_BEZA1301_0
(2-HYDROXY-6-OXO-7-ME
THYLOCTA-2,4-DIENOAT
E HYDROLASE)		 1adv ADENOVIRUS
SINGLE-STRANDED
DNA-BINDING PROTEIN
(Human
mastadenovirus
C) 		4 / 6 ARG A 189
LEU A 252
PHE A 255
ALA A 256
 None
 0.83A 1ukbA-1advA:
undetectable		 1ukbA-1advA:
21.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCV_L_ASDL1224_1
(GLUTATHIONE
S-TRANSFERASE A3)		 1adv ADENOVIRUS
SINGLE-STRANDED
DNA-BINDING PROTEIN
(Human
mastadenovirus
C) 		4 / 7 PRO A 393
LEU A 476
ALA A 479
PHE A 247
 None
 1.03A 2vcvL-1advA:
0.0		 2vcvL-1advA:
21.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VN1_A_FK5A501_2
(70 KDA
PEPTIDYLPROLYL
ISOMERASE)		 1adv ADENOVIRUS
SINGLE-STRANDED
DNA-BINDING PROTEIN
(Human
mastadenovirus
C) 		4 / 6 LEU A 415
SER A 354
PHE A 350
LYS A 414
 None
 0.96A 2vn1B-1advA:
0.0		 2vn1B-1advA:
15.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WX2_A_TPFA1460_1
(LANOSTEROL
14-ALPHA-DEMETHYLASE)		 1adv ADENOVIRUS
SINGLE-STRANDED
DNA-BINDING PROTEIN
(Human
mastadenovirus
C) 		4 / 7 MET A 357
PHE A 359
ALA A 365
LEU A 390
 None
 0.95A 2wx2A-1advA:
undetectable		 2wx2A-1advA:
22.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VM4_A_IZPA1_1
(FATTY ACID
ALPHA-HYDROXYLASE)		 1adv ADENOVIRUS
SINGLE-STRANDED
DNA-BINDING PROTEIN
(Human
mastadenovirus
C) 		4 / 5 LEU A 408
PHE A 407
ARG A 511
PRO A 406
 None
 1.32A 3vm4A-1advA:
0.0		 3vm4A-1advA:
21.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HHJ_B_GLYB404_0
(RETRON-TYPE REVERSE
TRANSCRIPTASE)		 1adv ADENOVIRUS
SINGLE-STRANDED
DNA-BINDING PROTEIN
(Human
mastadenovirus
C) 		4 / 4 GLN A 253
ALA A 250
GLN A 249
THR A 266
 None
 1.31A 5hhjB-1advA:
0.2		 5hhjB-1advA:
22.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XXI_A_LSNA503_1
(CYTOCHROME P450 2C9)		 1adv ADENOVIRUS
SINGLE-STRANDED
DNA-BINDING PROTEIN
(Human
mastadenovirus
C) 		5 / 12 LEU A 379
LEU A 232
THR A 233
PRO A 474
LEU A 445
 None
 1.12A 5xxiA-1advA:
0.0		 5xxiA-1advA:
19.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MXT_A_K5YA1401_1
(ENDOLYSIN, BETA-2
ADRENERGIC RECEPTOR
CHIMERA)		 1adv ADENOVIRUS
SINGLE-STRANDED
DNA-BINDING PROTEIN
(Human
mastadenovirus
C) 		3 / 3 ASP A 475
SER A 435
SER A 439
 None
 0.76A 6mxtA-1advA:
0.0		 6mxtA-1advA:
19.81