SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1ae7'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1SV9_A_DIFA701_1
(PHOSPHOLIPASE A2)		 1ae7 PHOSPHOLIPASE A2
(Notechis
scutatus) 		4 / 8 LEU A   2
GLY A  30
HIS A  48
PHE A 106
 None
 0.81A 1sv9A-1ae7A:
16.2		 1sv9A-1ae7A:
36.51
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1TH6_A_OINA401_1
(PHOSPHOLIPASE A2)		 1ae7 PHOSPHOLIPASE A2
(Notechis
scutatus) 		4 / 7 GLY A  30
HIS A  48
ASP A  49
TYR A  52
 None
 0.50A 1th6A-1ae7A:
16.2		 1th6A-1ae7A:
36.51
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2ARM_A_OINA401_1
(PHOSPHOLIPASE A2
VRV-PL-VIIIA)		 1ae7 PHOSPHOLIPASE A2
(Notechis
scutatus) 		4 / 7 GLY A  30
HIS A  48
ASP A  49
TYR A  52
 None
 0.51A 2armA-1ae7A:
16.2		 2armA-1ae7A:
36.51
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2AZY_A_CHDA237_0
(PHOSPHOLIPASE A2,
MAJOR ISOENZYME)		 1ae7 PHOSPHOLIPASE A2
(Notechis
scutatus) 		6 / 11 ILE A   9
TYR A  25
GLY A  30
LEU A  41
PHE A 106
TYR A 111
 None
 0.58A 2azyA-1ae7A:
16.8		 2azyA-1ae7A:
48.39
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2B17_A_DIFA701_1
(PHOSPHOLIPASE A2
VRV-PL-VIIIA)		 1ae7 PHOSPHOLIPASE A2
(Notechis
scutatus) 		5 / 10 LEU A   2
GLY A  30
HIS A  48
ASP A  49
PHE A 106
 None
 0.78A 2b17A-1ae7A:
16.2		 2b17A-1ae7A:
36.51
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2DPZ_A_TYLA2001_1
(PHOSPHOLIPASE A2
VRV-PL-VIIIA)		 1ae7 PHOSPHOLIPASE A2
(Notechis
scutatus) 		4 / 6 LEU A   2
HIS A  48
ASP A  49
TYR A  52
 None
 0.66A 2dpzA-1ae7A:
16.4		 2dpzA-1ae7A:
36.51
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3OSH_A_OINA5811_1
(PHOSPHOLIPASE A2
ISOFORM 3)		 1ae7 PHOSPHOLIPASE A2
(Notechis
scutatus) 		5 / 9 LEU A   2
PHE A   5
ILE A   9
GLY A  30
HIS A  48
 None
 0.75A 3oshA-1ae7A:
19.0		 3oshA-1ae7A:
53.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WIP_A_ACHA301_0
(ACETYLCHOLINE-BINDIN
G PROTEIN)		 1ae7 PHOSPHOLIPASE A2
(Notechis
scutatus) 		4 / 7 TRP A  20
THR A  19
TYR A 111
TYR A  22
 None
 1.16A 3wipA-1ae7A:
undetectable
3wipB-1ae7A:
undetectable		 3wipA-1ae7A:
16.50
3wipB-1ae7A:
16.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WIP_B_ACHB301_0
(ACETYLCHOLINE-BINDIN
G PROTEIN)		 1ae7 PHOSPHOLIPASE A2
(Notechis
scutatus) 		4 / 8 TRP A  20
THR A  19
TYR A 111
TYR A  22
 None
 1.20A 3wipB-1ae7A:
undetectable
3wipC-1ae7A:
undetectable		 3wipB-1ae7A:
16.50
3wipC-1ae7A:
16.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WIP_D_ACHD301_0
(ACETYLCHOLINE-BINDIN
G PROTEIN)		 1ae7 PHOSPHOLIPASE A2
(Notechis
scutatus) 		4 / 8 TRP A  20
THR A  19
TYR A 111
TYR A  22
 None
 1.21A 3wipD-1ae7A:
undetectable
3wipE-1ae7A:
undetectable		 3wipD-1ae7A:
16.50
3wipE-1ae7A:
16.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WIP_E_ACHE301_0
(ACETYLCHOLINE-BINDIN
G PROTEIN)		 1ae7 PHOSPHOLIPASE A2
(Notechis
scutatus) 		4 / 8 TRP A  20
THR A  19
TYR A 111
TYR A  22
 None
 1.23A 3wipA-1ae7A:
undetectable
3wipE-1ae7A:
undetectable		 3wipA-1ae7A:
16.50
3wipE-1ae7A:
16.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WIP_G_ACHG301_0
(ACETYLCHOLINE-BINDIN
G PROTEIN)		 1ae7 PHOSPHOLIPASE A2
(Notechis
scutatus) 		4 / 8 TRP A  20
THR A  19
TYR A 111
TYR A  22
 None
 1.22A 3wipG-1ae7A:
0.0
3wipH-1ae7A:
0.0		 3wipG-1ae7A:
16.50
3wipH-1ae7A:
16.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WIP_J_ACHJ301_0
(ACETYLCHOLINE-BINDIN
G PROTEIN)		 1ae7 PHOSPHOLIPASE A2
(Notechis
scutatus) 		4 / 8 TRP A  20
THR A  19
TYR A 111
TYR A  22
 None
 1.16A 3wipF-1ae7A:
0.0
3wipJ-1ae7A:
0.0		 3wipF-1ae7A:
16.50
3wipJ-1ae7A:
16.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OLT_B_GCSB304_1
(CHITOSANASE)		 1ae7 PHOSPHOLIPASE A2
(Notechis
scutatus) 		4 / 5 ILE A   9
THR A  19
HIS A  48
TYR A  73
 None
 1.29A 4oltB-1ae7A:
undetectable		 4oltB-1ae7A:
17.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QWP_A_GCSA303_1
(CHITOSANASE)		 1ae7 PHOSPHOLIPASE A2
(Notechis
scutatus) 		4 / 6 ILE A   9
THR A  19
HIS A  48
TYR A  73
 None
 1.24A 4qwpA-1ae7A:
undetectable		 4qwpA-1ae7A:
17.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IGI_A_ZITA402_2
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E)		 1ae7 PHOSPHOLIPASE A2
(Notechis
scutatus) 		4 / 6 HIS A  48
GLU A 101
LEU A  92
TYR A  75
 None
 1.09A 5igiA-1ae7A:
undetectable		 5igiA-1ae7A:
14.62