SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1aep'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RLB_E_REAE176_1
(RETINOL BINDING
PROTEIN)		 1aep APOLIPOPHORIN III
(Locusta
migratoria) 		5 / 10 LEU A  81
ALA A 133
ALA A 137
VAL A 108
LEU A  14
 None
 1.31A 1rlbE-1aepA:
undetectable		 1rlbE-1aepA:
21.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3L4D_D_TPFD490_1
(STEROL 14-ALPHA
DEMETHYLASE)		 1aep APOLIPOPHORIN III
(Locusta
migratoria) 		4 / 8 ALA A 133
ALA A 137
THR A 141
LEU A  81
 None
 1.03A 3l4dD-1aepA:
undetectable		 3l4dD-1aepA:
15.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TGV_B_BEZB160_0
(HEME-BINDING PROTEIN
HUTZ)		 1aep APOLIPOPHORIN III
(Locusta
migratoria) 		4 / 4 LEU A  31
GLY A  30
LEU A  29
GLU A  27
 None
 0.93A 3tgvB-1aepA:
undetectable		 3tgvB-1aepA:
19.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WG0_M_CHDM103_0
(NUCLEAR RECEPTOR
COACTIVATOR 2)		 1aep APOLIPOPHORIN III
(Locusta
migratoria) 		5 / 11 GLU A  27
LEU A  29
GLU A  24
LEU A  41
LEU A  94
 None
 1.09A 4wg0K-1aepA:
undetectable
4wg0L-1aepA:
undetectable
4wg0M-1aepA:
undetectable		 4wg0K-1aepA:
7.83
4wg0L-1aepA:
7.83
4wg0M-1aepA:
7.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AJQ_B_DB8B800_1
(SERINE/THREONINE-PRO
TEIN KINASE 10)		 1aep APOLIPOPHORIN III
(Locusta
migratoria) 		5 / 10 ALA A 116
ILE A   7
GLY A 109
LEU A  14
ALA A 138
 None
 1.40A 5ajqB-1aepA:
undetectable		 5ajqB-1aepA:
20.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CI6_A_NBOA607_1
(SERUM ALBUMIN)		 1aep APOLIPOPHORIN III
(Locusta
migratoria) 		4 / 7 ASN A  46
ALA A  47
LYS A  51
GLU A  54
 None
 1.03A 6ci6A-1aepA:
1.6		 6ci6A-1aepA:
16.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F3M_D_ADND502_2
(-)		 1aep APOLIPOPHORIN III
(Locusta
migratoria) 		4 / 5 ILE A 115
GLN A 120
THR A 119
LEU A  14
 None
 1.14A 6f3mD-1aepA:
undetectable		 6f3mD-1aepA:
17.67