SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1af5'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AB2_A_SNLA502_2
(MINERALOCORTICOID
RECEPTOR)		 1af5 I-CREI
(Chlamydomonas
reinhardtii) 		4 / 6 LEU A  91
LEU A  88
LEU A  78
LEU A  58
 None
 0.90A 2ab2A-1af5A:
undetectable		 2ab2A-1af5A:
18.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PNJ_A_CHDA501_0
(FERROCHELATASE,
MITOCHONDRIAL)		 1af5 I-CREI
(Chlamydomonas
reinhardtii) 		5 / 12 LEU A  91
LEU A  88
PHE A  87
LEU A  84
VAL A  45
 None
 1.07A 2pnjA-1af5A:
undetectable		 2pnjA-1af5A:
18.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VQ5_B_LDPB1197_1
(S-NORCOCLAURINE
SYNTHASE)		 1af5 I-CREI
(Chlamydomonas
reinhardtii) 		4 / 7 LEU A  13
LEU A  10
PHE A   9
LEU A  58
 None
 0.91A 2vq5B-1af5A:
undetectable		 2vq5B-1af5A:
22.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G1U_C_ADNC438_1
(ADENOSYLHOMOCYSTEINA
SE)		 1af5 I-CREI
(Chlamydomonas
reinhardtii) 		5 / 12 LEU A  58
GLU A  61
LEU A  91
GLY A  15
PHE A  54
 None
 1.31A 3g1uC-1af5A:
undetectable		 3g1uC-1af5A:
16.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TPX_E_ACTE204_0
(E3 UBIQUITIN-PROTEIN
LIGASE MDM2)		 1af5 I-CREI
(Chlamydomonas
reinhardtii) 		3 / 3 LYS A  82
PRO A  83
LEU A  84
 None
 0.82A 3tpxE-1af5A:
0.0		 3tpxE-1af5A:
21.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OTW_A_DB8A1101_2
(RECEPTOR
TYROSINE-PROTEIN
KINASE ERBB-3)		 1af5 I-CREI
(Chlamydomonas
reinhardtii) 		3 / 3 LEU A  41
LEU A  91
ASN A 103
 None
 0.73A 4otwA-1af5A:
undetectable		 4otwA-1af5A:
19.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6APH_A_ADNA501_1
(ADENOSYLHOMOCYSTEINA
SE)		 1af5 I-CREI
(Chlamydomonas
reinhardtii) 		5 / 12 LEU A  58
GLU A  61
LEU A  91
GLY A  15
PHE A  54
 None
 1.27A 6aphA-1af5A:
undetectable		 6aphA-1af5A:
15.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GBN_B_ADNB501_1
(-)		 1af5 I-CREI
(Chlamydomonas
reinhardtii) 		5 / 12 LEU A  58
GLU A  61
LEU A  10
GLY A  15
PHE A  54
 None
 1.44A 6gbnB-1af5A:
undetectable		 6gbnB-1af5A:
12.79