SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1ag9'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1BU5_A_RBFA301_1
(PROTEIN (FLAVODOXIN))		 1ag9 FLAVODOXIN
(Escherichia
coli) 		7 / 7 THR A  12
ASN A  14
THR A  56
TRP A  57
GLY A  89
ASP A  90
TYR A  94
 FMN  A 177 (-3.5A)
FMN  A 177 (-3.9A)
FMN  A 177 (-3.9A)
FMN  A 177 (-3.7A)
FMN  A 177 (-3.2A)
None
FMN  A 177 (-3.4A)
 0.71A 1bu5A-1ag9A:
20.3		 1bu5A-1ag9A:
34.25
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1BU5_B_RBFB302_1
(PROTEIN (FLAVODOXIN))		 1ag9 FLAVODOXIN
(Escherichia
coli) 		6 / 8 THR A  12
ASN A  14
THR A  56
GLY A  89
ASP A  90
TYR A  94
 FMN  A 177 (-3.5A)
FMN  A 177 (-3.9A)
FMN  A 177 (-3.9A)
FMN  A 177 (-3.2A)
None
FMN  A 177 (-3.4A)
 0.48A 1bu5B-1ag9A:
20.2		 1bu5B-1ag9A:
34.25
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1BU5_B_RBFB302_1
(PROTEIN (FLAVODOXIN))		 1ag9 FLAVODOXIN
(Escherichia
coli) 		5 / 8 THR A  56
TRP A  57
GLY A  89
ASP A  90
TYR A  94
 FMN  A 177 (-3.9A)
FMN  A 177 (-3.7A)
FMN  A 177 (-3.2A)
None
FMN  A 177 (-3.4A)
 0.63A 1bu5B-1ag9A:
20.2		 1bu5B-1ag9A:
34.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C4D_A_DVAA8_0
(GRAMICIDIN A)		 1ag9 FLAVODOXIN
(Escherichia
coli) 		3 / 3 VAL A 140
TRP A 120
TRP A 160
 None
 1.31A 1c4dA-1ag9A:
undetectable
1c4dB-1ag9A:
undetectable		 1c4dA-1ag9A:
6.80
1c4dB-1ag9A:
6.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MEH_A_MOAA600_1
(INOSINE-5'-MONOPHOSP
HATE DEHYDROGENASE)		 1ag9 FLAVODOXIN
(Escherichia
coli) 		5 / 10 ASP A  35
ILE A  54
GLY A  87
GLU A  16
GLY A  13
 None
None
None
None
FMN  A 177 (-3.8A)
 1.16A 1mehA-1ag9A:
undetectable		 1mehA-1ag9A:
18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SH9_B_RITB301_1
(POL POLYPROTEIN)		 1ag9 FLAVODOXIN
(Escherichia
coli) 		5 / 8 ALA A  84
ILE A  22
ILE A   6
GLY A  53
ILE A  54
 None
 1.25A 1sh9A-1ag9A:
0.0		 1sh9A-1ag9A:
24.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T85_A_CAMA422_0
(CYTOCHROME P450-CAM)		 1ag9 FLAVODOXIN
(Escherichia
coli) 		4 / 7 THR A   4
LEU A  26
VAL A 161
VAL A 117
 None
 1.00A 1t85A-1ag9A:
0.0		 1t85A-1ag9A:
23.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T87_A_CAMA1422_0
(CYTOCHROME P450-CAM)		 1ag9 FLAVODOXIN
(Escherichia
coli) 		4 / 7 THR A   4
LEU A  26
VAL A 161
VAL A 117
 None
 1.00A 1t87A-1ag9A:
0.0		 1t87A-1ag9A:
23.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YRC_A_CAMA420_0
(CYTOCHROME P450-CAM)		 1ag9 FLAVODOXIN
(Escherichia
coli) 		4 / 7 THR A   4
LEU A  26
VAL A 161
VAL A 117
 None
 0.95A 1yrcA-1ag9A:
0.0		 1yrcA-1ag9A:
23.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YRD_A_CAMA420_0
(CYTOCHROME P450-CAM)		 1ag9 FLAVODOXIN
(Escherichia
coli) 		4 / 7 THR A   4
LEU A  26
VAL A 161
VAL A 117
 None
 0.96A 1yrdA-1ag9A:
0.0		 1yrdA-1ag9A:
23.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FEU_A_CAMA1420_0
(CYTOCHROME P450-CAM)		 1ag9 FLAVODOXIN
(Escherichia
coli) 		4 / 6 THR A   4
LEU A  26
VAL A 161
VAL A 117
 None
 0.95A 2feuA-1ag9A:
0.0		 2feuA-1ag9A:
24.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FEU_B_CAMB1421_0
(CYTOCHROME P450-CAM)		 1ag9 FLAVODOXIN
(Escherichia
coli) 		4 / 7 THR A   4
LEU A  26
VAL A 161
VAL A 117
 None
 0.94A 2feuB-1ag9A:
undetectable		 2feuB-1ag9A:
24.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V0M_C_KLNC1499_1
(CYTOCHROME P450 3A4)		 1ag9 FLAVODOXIN
(Escherichia
coli) 		4 / 7 LEU A  50
PHE A  78
ILE A 105
GLY A   5
 None
 0.91A 2v0mC-1ag9A:
undetectable		 2v0mC-1ag9A:
15.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZUH_A_CAMA422_0
(CAMPHOR
5-MONOOXYGENASE)		 1ag9 FLAVODOXIN
(Escherichia
coli) 		4 / 6 THR A   4
LEU A  26
VAL A 161
VAL A 117
 None
 1.02A 2zuhA-1ag9A:
0.0		 2zuhA-1ag9A:
23.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZUI_A_CAMA422_0
(CAMPHOR
5-MONOOXYGENASE)		 1ag9 FLAVODOXIN
(Escherichia
coli) 		4 / 6 THR A   4
LEU A  26
VAL A 161
VAL A 117
 None
 0.96A 2zuiA-1ag9A:
0.0		 2zuiA-1ag9A:
23.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZWT_A_CAMA422_0
(CAMPHOR
5-MONOOXYGENASE)		 1ag9 FLAVODOXIN
(Escherichia
coli) 		4 / 7 THR A   4
LEU A  26
VAL A 161
VAL A 117
 None
 0.95A 2zwtA-1ag9A:
0.0		 2zwtA-1ag9A:
23.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZWU_A_CAMA422_0
(CAMPHOR
5-MONOOXYGENASE)		 1ag9 FLAVODOXIN
(Escherichia
coli) 		4 / 7 THR A   4
LEU A  26
VAL A 161
VAL A 117
 None
 0.95A 2zwuA-1ag9A:
0.0		 2zwuA-1ag9A:
23.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CS9_D_NILD600_2
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE ABL1)		 1ag9 FLAVODOXIN
(Escherichia
coli) 		4 / 6 LEU A  50
VAL A  83
LEU A  73
ASP A 107
 None
 0.85A 3cs9D-1ag9A:
undetectable		 3cs9D-1ag9A:
21.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FWF_A_CAMA420_0
(CAMPHOR
5-MONOOXYGENASE)		 1ag9 FLAVODOXIN
(Escherichia
coli) 		4 / 7 THR A   4
LEU A  26
VAL A 161
VAL A 117
 None
 0.94A 3fwfA-1ag9A:
undetectable		 3fwfA-1ag9A:
24.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FWF_B_CAMB420_0
(CAMPHOR
5-MONOOXYGENASE)		 1ag9 FLAVODOXIN
(Escherichia
coli) 		4 / 7 THR A   4
LEU A  26
VAL A 161
VAL A 117
 None
 0.93A 3fwfB-1ag9A:
0.0		 3fwfB-1ag9A:
24.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FWI_A_CAMA420_0
(CAMPHOR
5-MONOOXYGENASE)		 1ag9 FLAVODOXIN
(Escherichia
coli) 		4 / 7 THR A   4
LEU A  26
VAL A 161
VAL A 117
 None
 1.00A 3fwiA-1ag9A:
undetectable		 3fwiA-1ag9A:
24.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FWJ_A_CAMA420_0
(CAMPHOR
5-MONOOXYGENASE)		 1ag9 FLAVODOXIN
(Escherichia
coli) 		4 / 7 THR A   4
LEU A  26
VAL A 161
VAL A 117
 None
 0.94A 3fwjA-1ag9A:
0.0		 3fwjA-1ag9A:
24.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_A_TFPA202_1
(PROTEIN S100-A4)		 1ag9 FLAVODOXIN
(Escherichia
coli) 		5 / 12 LEU A 142
PHE A  86
ILE A  18
ASP A 145
SER A 130
 None
 1.20A 3ko0A-1ag9A:
undetectable
3ko0B-1ag9A:
undetectable
3ko0C-1ag9A:
undetectable
3ko0D-1ag9A:
undetectable		 3ko0A-1ag9A:
22.70
3ko0B-1ag9A:
22.70
3ko0C-1ag9A:
22.70
3ko0D-1ag9A:
22.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_D_TFPD202_1
(PROTEIN S100-A4)		 1ag9 FLAVODOXIN
(Escherichia
coli) 		5 / 11 ASP A 145
LEU A 142
PHE A  86
ILE A  18
SER A 130
 None
 1.22A 3ko0C-1ag9A:
undetectable
3ko0D-1ag9A:
undetectable
3ko0E-1ag9A:
undetectable
3ko0F-1ag9A:
undetectable		 3ko0C-1ag9A:
22.70
3ko0D-1ag9A:
22.70
3ko0E-1ag9A:
22.70
3ko0F-1ag9A:
22.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_E_TFPE202_1
(PROTEIN S100-A4)		 1ag9 FLAVODOXIN
(Escherichia
coli) 		5 / 11 SER A 130
LEU A 142
PHE A  86
ILE A  18
ASP A 145
 None
 1.24A 3ko0C-1ag9A:
undetectable
3ko0D-1ag9A:
undetectable
3ko0E-1ag9A:
undetectable
3ko0F-1ag9A:
undetectable		 3ko0C-1ag9A:
22.70
3ko0D-1ag9A:
22.70
3ko0E-1ag9A:
22.70
3ko0F-1ag9A:
22.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_H_TFPH202_1
(PROTEIN S100-A4)		 1ag9 FLAVODOXIN
(Escherichia
coli) 		5 / 12 ASP A 145
LEU A 142
PHE A  86
ILE A  18
SER A 130
 None
 1.19A 3ko0G-1ag9A:
undetectable
3ko0H-1ag9A:
undetectable
3ko0I-1ag9A:
undetectable
3ko0J-1ag9A:
undetectable		 3ko0G-1ag9A:
22.70
3ko0H-1ag9A:
22.70
3ko0I-1ag9A:
22.70
3ko0J-1ag9A:
22.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_J_TFPJ202_1
(PROTEIN S100-A4)		 1ag9 FLAVODOXIN
(Escherichia
coli) 		5 / 11 SER A 130
ASP A 145
LEU A 142
PHE A  86
ILE A  18
 None
 1.24A 3ko0A-1ag9A:
undetectable
3ko0B-1ag9A:
undetectable
3ko0I-1ag9A:
undetectable
3ko0J-1ag9A:
undetectable		 3ko0A-1ag9A:
22.70
3ko0B-1ag9A:
22.70
3ko0I-1ag9A:
22.70
3ko0J-1ag9A:
22.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_K_TFPK202_1
(PROTEIN S100-A4)		 1ag9 FLAVODOXIN
(Escherichia
coli) 		5 / 12 LEU A 142
PHE A  86
ILE A  18
ASP A 145
SER A 130
 None
 1.11A 3ko0K-1ag9A:
undetectable
3ko0L-1ag9A:
undetectable
3ko0S-1ag9A:
undetectable
3ko0T-1ag9A:
undetectable		 3ko0K-1ag9A:
22.70
3ko0L-1ag9A:
22.70
3ko0S-1ag9A:
22.70
3ko0T-1ag9A:
22.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_M_TFPM202_1
(PROTEIN S100-A4)		 1ag9 FLAVODOXIN
(Escherichia
coli) 		5 / 12 LEU A 142
PHE A  86
ILE A  18
ASP A 145
SER A 130
 None
 1.13A 3ko0M-1ag9A:
undetectable
3ko0N-1ag9A:
undetectable
3ko0O-1ag9A:
undetectable
3ko0P-1ag9A:
undetectable		 3ko0M-1ag9A:
22.70
3ko0N-1ag9A:
22.70
3ko0O-1ag9A:
22.70
3ko0P-1ag9A:
22.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_O_TFPO202_1
(PROTEIN S100-A4)		 1ag9 FLAVODOXIN
(Escherichia
coli) 		5 / 11 LEU A 142
PHE A  86
ILE A  18
ASP A 145
SER A 130
 None
 1.24A 3ko0O-1ag9A:
undetectable
3ko0P-1ag9A:
undetectable
3ko0Q-1ag9A:
undetectable
3ko0R-1ag9A:
undetectable		 3ko0O-1ag9A:
22.70
3ko0P-1ag9A:
22.70
3ko0Q-1ag9A:
22.70
3ko0R-1ag9A:
22.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_P_TFPP202_1
(PROTEIN S100-A4)		 1ag9 FLAVODOXIN
(Escherichia
coli) 		5 / 12 SER A 130
ASP A 145
LEU A 142
PHE A  86
ILE A  18
 None
 1.18A 3ko0M-1ag9A:
undetectable
3ko0N-1ag9A:
undetectable
3ko0O-1ag9A:
undetectable
3ko0P-1ag9A:
undetectable		 3ko0M-1ag9A:
22.70
3ko0N-1ag9A:
22.70
3ko0O-1ag9A:
22.70
3ko0P-1ag9A:
22.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3L63_A_CAMA440_0
(CAMPHOR
5-MONOOXYGENASE)		 1ag9 FLAVODOXIN
(Escherichia
coli) 		4 / 7 THR A   4
LEU A  26
VAL A 161
VAL A 117
 None
 0.92A 3l63A-1ag9A:
0.0		 3l63A-1ag9A:
23.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SUD_B_SUEB1201_1
(NS3 PROTEASE, NS4A
PROTEIN)		 1ag9 FLAVODOXIN
(Escherichia
coli) 		5 / 12 TYR A  58
GLY A  60
ILE A 108
GLY A 103
ALA A 101
 None
FMN  A 177 (-3.8A)
None
None
None
 1.04A 3sudB-1ag9A:
undetectable		 3sudB-1ag9A:
19.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TTR_A_LQZA90_1
(LACTOTRANSFERRIN)		 1ag9 FLAVODOXIN
(Escherichia
coli) 		3 / 3 PRO A 121
THR A 122
LEU A 133
 None
 0.80A 3ttrA-1ag9A:
1.9		 3ttrA-1ag9A:
17.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WRH_A_CAMA503_0
(CAMPHOR
5-MONOOXYGENASE)		 1ag9 FLAVODOXIN
(Escherichia
coli) 		4 / 7 THR A   4
LEU A  26
VAL A 161
VAL A 117
 None
 0.95A 3wrhA-1ag9A:
0.0		 3wrhA-1ag9A:
23.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WRJ_A_CAMA503_0
(CAMPHOR
5-MONOOXYGENASE)		 1ag9 FLAVODOXIN
(Escherichia
coli) 		4 / 7 THR A   4
LEU A  26
VAL A 161
VAL A 117
 None
 0.96A 3wrjA-1ag9A:
undetectable		 3wrjA-1ag9A:
23.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WRL_A_CAMA503_0
(CAMPHOR
5-MONOOXYGENASE)		 1ag9 FLAVODOXIN
(Escherichia
coli) 		4 / 7 THR A   4
LEU A  26
VAL A 161
VAL A 117
 None
 0.93A 3wrlA-1ag9A:
0.0		 3wrlA-1ag9A:
23.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WRL_E_CAME503_0
(CAMPHOR
5-MONOOXYGENASE)		 1ag9 FLAVODOXIN
(Escherichia
coli) 		4 / 7 THR A   4
LEU A  26
VAL A 161
VAL A 117
 None
 0.94A 3wrlE-1ag9A:
0.0		 3wrlE-1ag9A:
23.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WRM_A_CAMA503_0
(CAMPHOR
5-MONOOXYGENASE)		 1ag9 FLAVODOXIN
(Escherichia
coli) 		4 / 7 THR A   4
LEU A  26
VAL A 161
VAL A 117
 None
 0.96A 3wrmA-1ag9A:
0.0		 3wrmA-1ag9A:
23.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WRM_F_CAMF503_0
(CAMPHOR
5-MONOOXYGENASE)		 1ag9 FLAVODOXIN
(Escherichia
coli) 		4 / 7 THR A   4
LEU A  26
VAL A 161
VAL A 117
 None
 0.95A 3wrmF-1ag9A:
undetectable		 3wrmF-1ag9A:
23.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IKI_A_IMNA201_1
(TRANSTHYRETIN)		 1ag9 FLAVODOXIN
(Escherichia
coli) 		3 / 3 LYS A  81
LEU A  50
ALA A 114
 None
 0.73A 4ikiA-1ag9A:
0.0		 4ikiA-1ag9A:
23.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L4A_A_CAMA502_0
(CAMPHOR
5-MONOOXYGENASE)		 1ag9 FLAVODOXIN
(Escherichia
coli) 		4 / 8 THR A   4
LEU A  26
VAL A 161
VAL A 117
 None
 0.99A 4l4aA-1ag9A:
0.0		 4l4aA-1ag9A:
24.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L4G_A_CAMA503_0
(CAMPHOR
5-MONOOXYGENASE)		 1ag9 FLAVODOXIN
(Escherichia
coli) 		4 / 7 THR A   4
LEU A  26
VAL A 161
VAL A 117
 None
 0.98A 4l4gA-1ag9A:
0.0		 4l4gA-1ag9A:
24.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WG0_J_CHDJ103_0
(NUCLEAR RECEPTOR
COACTIVATOR 2)		 1ag9 FLAVODOXIN
(Escherichia
coli) 		5 / 11 LEU A  50
LEU A  52
LEU A  44
GLU A  75
LEU A  73
 None
 0.99A 4wg0J-1ag9A:
undetectable
4wg0K-1ag9A:
undetectable
4wg0L-1ag9A:
undetectable		 4wg0J-1ag9A:
6.57
4wg0K-1ag9A:
6.57
4wg0L-1ag9A:
6.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Y8W_A_STRA604_1
(CYTOCHROME P450
21-HYDROXYLASE)		 1ag9 FLAVODOXIN
(Escherichia
coli) 		5 / 12 LEU A  73
ASP A 107
ILE A 108
VAL A  83
LEU A  85
 None
 1.04A 4y8wA-1ag9A:
0.0		 4y8wA-1ag9A:
16.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WK9_A_CAMA503_0
(CAMPHOR
5-MONOOXYGENASE)		 1ag9 FLAVODOXIN
(Escherichia
coli) 		4 / 7 THR A   4
LEU A  26
VAL A 161
VAL A 117
 None
 0.95A 5wk9A-1ag9A:
0.0		 5wk9A-1ag9A:
23.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B58_A_ACTA606_0
(FUMARATE REDUCTASE
FLAVOPROTEIN SUBUNIT)		 1ag9 FLAVODOXIN
(Escherichia
coli) 		4 / 5 GLU A  74
PHE A  70
ASP A  67
THR A 104
 None
None
NA  A 401 ( 2.6A)
CL  A 405 ( 3.9A)
 1.32A 6b58A-1ag9A:
1.3		 6b58A-1ag9A:
14.29