SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1agx'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MT1_G_AG2G7003_1
(PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE BETA
CHAIN
PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE ALPHA
CHAIN)		 1agx GLUTAMINASE-ASPARAGI
NASE
(Acinetobacter
glutaminasifican
s) 		4 / 6 LEU A  68
ASP A  64
GLY A 217
ARG A 308
 None
 0.71A 1mt1G-1agxA:
0.0
1mt1J-1agxA:
0.0		 1mt1G-1agxA:
12.68
1mt1J-1agxA:
17.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MT1_K_AG2K7002_1
(PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE ALPHA
CHAIN
PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE BETA
CHAIN)		 1agx GLUTAMINASE-ASPARAGI
NASE
(Acinetobacter
glutaminasifican
s) 		4 / 7 ARG A 308
LEU A  68
ASP A  64
GLY A 217
 None
 0.72A 1mt1H-1agxA:
0.0
1mt1K-1agxA:
0.0		 1mt1H-1agxA:
17.22
1mt1K-1agxA:
12.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1N13_D_AG2D7015_1
(PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE ALPHA
CHAIN
PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE BETA
CHAIN)		 1agx GLUTAMINASE-ASPARAGI
NASE
(Acinetobacter
glutaminasifican
s) 		4 / 7 ARG A 308
LEU A  68
ASP A  64
GLY A 217
 None
 0.74A 1n13D-1agxA:
0.0
1n13E-1agxA:
undetectable		 1n13D-1agxA:
17.22
1n13E-1agxA:
12.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1N13_D_AG2D7015_1
(PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE ALPHA
CHAIN
PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE BETA
CHAIN)		 1agx GLUTAMINASE-ASPARAGI
NASE
(Acinetobacter
glutaminasifican
s) 		4 / 7 LEU A 309
ARG A 308
LEU A  68
ASP A  64
 None
 0.85A 1n13D-1agxA:
0.0
1n13E-1agxA:
undetectable		 1n13D-1agxA:
17.22
1n13E-1agxA:
12.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1N13_F_AG2F7016_1
(PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE BETA
CHAIN
PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE ALPHA
CHAIN)		 1agx GLUTAMINASE-ASPARAGI
NASE
(Acinetobacter
glutaminasifican
s) 		4 / 8 LEU A  68
ASP A  64
GLY A 217
ARG A 308
 None
 0.77A 1n13A-1agxA:
0.0
1n13F-1agxA:
0.0		 1n13A-1agxA:
12.68
1n13F-1agxA:
17.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1N13_H_AG2H7012_1
(PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE ALPHA
CHAIN
PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE BETA
CHAIN)		 1agx GLUTAMINASE-ASPARAGI
NASE
(Acinetobacter
glutaminasifican
s) 		4 / 6 ARG A 308
LEU A  68
ASP A  64
GLY A 217
 None
 0.78A 1n13H-1agxA:
0.0
1n13K-1agxA:
0.0		 1n13H-1agxA:
17.22
1n13K-1agxA:
12.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1N13_J_AG2J7013_1
(PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE BETA
CHAIN
PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE ALPHA
CHAIN)		 1agx GLUTAMINASE-ASPARAGI
NASE
(Acinetobacter
glutaminasifican
s) 		4 / 7 LEU A  68
ASP A  64
GLY A 217
ARG A 308
 None
 0.77A 1n13G-1agxA:
0.0
1n13J-1agxA:
0.0		 1n13G-1agxA:
12.68
1n13J-1agxA:
17.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AJY_H_BEZH306_0
(ANTIBODY 7A1 FAB')		 1agx GLUTAMINASE-ASPARAGI
NASE
(Acinetobacter
glutaminasifican
s) 		4 / 4 ASN A  22
ALA A 123
ARG A 119
TYR A  26
 None
 1.48A 2ajyH-1agxA:
0.0		 2ajyH-1agxA:
21.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AK1_H_BEZH401_0
(ANTIBODY 7A1 FAB')		 1agx GLUTAMINASE-ASPARAGI
NASE
(Acinetobacter
glutaminasifican
s) 		4 / 4 ASN A  22
ALA A 123
ARG A 119
TYR A  26
 None
 1.49A 2ak1H-1agxA:
0.0		 2ak1H-1agxA:
21.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AOJ_C_FRDC305_2
(POL POLYPROTEIN
PEPTIDE INHIBITOR)		 1agx GLUTAMINASE-ASPARAGI
NASE
(Acinetobacter
glutaminasifican
s) 		4 / 7 LEU A  70
GLY A  51
ILE A   6
VAL A  74
 None
 0.76A 2aojB-1agxA:
0.0		 2aojB-1agxA:
17.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QHF_A_ACTA508_0
(CHORISMATE SYNTHASE)		 1agx GLUTAMINASE-ASPARAGI
NASE
(Acinetobacter
glutaminasifican
s) 		4 / 5 LEU A  36
ASP A  34
ALA A  35
ILE A   6
 None
 1.11A 2qhfA-1agxA:
0.0		 2qhfA-1agxA:
22.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QQC_K_AG2K671_1
(PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE (EC
4.1.1.19) (PVLARGDC))		 1agx GLUTAMINASE-ASPARAGI
NASE
(Acinetobacter
glutaminasifican
s) 		4 / 8 ARG A 308
LEU A  68
ASP A  64
GLY A 217
 None
 0.78A 2qqcH-1agxA:
0.0
2qqcK-1agxA:
0.0		 2qqcH-1agxA:
17.48
2qqcK-1agxA:
13.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2UXP_A_CLMA1211_0
(HTH-TYPE
TRANSCRIPTIONAL
REGULATOR TTGR)		 1agx GLUTAMINASE-ASPARAGI
NASE
(Acinetobacter
glutaminasifican
s) 		5 / 8 LEU A  36
LEU A 132
ILE A  49
VAL A  87
ILE A  88
 None
 1.41A 2uxpA-1agxA:
0.4		 2uxpA-1agxA:
20.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Z0A_A_GLYA73_0
(NONSTRUCTURAL
PROTEIN 1)		 1agx GLUTAMINASE-ASPARAGI
NASE
(Acinetobacter
glutaminasifican
s) 		4 / 5 GLN A  73
ALA A  54
GLN A  53
ILE A  52
 None
 1.48A 2z0aA-1agxA:
undetectable		 2z0aA-1agxA:
14.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABK_P_CHDP1271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1agx GLUTAMINASE-ASPARAGI
NASE
(Acinetobacter
glutaminasifican
s) 		4 / 6 LEU A 313
PHE A 205
LEU A 104
PHE A 100
 None
 0.99A 3abkP-1agxA:
undetectable
3abkW-1agxA:
undetectable		 3abkP-1agxA:
21.25
3abkW-1agxA:
11.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASO_C_CHDC271_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1)		 1agx GLUTAMINASE-ASPARAGI
NASE
(Acinetobacter
glutaminasifican
s) 		4 / 8 LEU A 313
PHE A 205
LEU A 104
PHE A 100
 None
 0.90A 3asoC-1agxA:
undetectable
3asoJ-1agxA:
0.0		 3asoC-1agxA:
21.25
3asoJ-1agxA:
11.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DVAC59_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		 1agx GLUTAMINASE-ASPARAGI
NASE
(Acinetobacter
glutaminasifican
s) 		3 / 3 GLY A 223
GLY A 249
GLY A 247
 None
 0.33A 3bogC-1agxA:
undetectable		 3bogC-1agxA:
15.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SM2_A_478A126_2
(GAG-PRO-POL
POLYPROTEIN)		 1agx GLUTAMINASE-ASPARAGI
NASE
(Acinetobacter
glutaminasifican
s) 		5 / 11 HIS A  90
VAL A 115
GLY A  15
ALA A  16
PRO A 129
 None
 0.91A 3sm2B-1agxA:
undetectable		 3sm2B-1agxA:
18.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TBG_D_RTZD2_1
(CYTOCHROME P450 2D6)		 1agx GLUTAMINASE-ASPARAGI
NASE
(Acinetobacter
glutaminasifican
s) 		5 / 9 LEU A  55
VAL A  57
LEU A  67
THR A  63
ILE A  62
 None
 1.18A 3tbgD-1agxA:
0.0		 3tbgD-1agxA:
21.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C49_A_HCYA1384_1
(CORTICOSTEROID-BINDI
NG GLOBULIN)		 1agx GLUTAMINASE-ASPARAGI
NASE
(Acinetobacter
glutaminasifican
s) 		5 / 12 ALA A 135
SER A 134
THR A   9
ILE A  13
HIS A  90
 None
 1.22A 4c49A-1agxA:
0.0		 4c49A-1agxA:
21.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J24_A_ESTA600_1
(ESTROGEN RECEPTOR
BETA)		 1agx GLUTAMINASE-ASPARAGI
NASE
(Acinetobacter
glutaminasifican
s) 		5 / 12 LEU A 313
LEU A 310
ILE A 210
ILE A 207
LEU A  67
 None
 1.12A 4j24A-1agxA:
undetectable		 4j24A-1agxA:
24.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J24_B_ESTB600_1
(ESTROGEN RECEPTOR
BETA)		 1agx GLUTAMINASE-ASPARAGI
NASE
(Acinetobacter
glutaminasifican
s) 		5 / 12 LEU A 313
LEU A 310
ILE A 210
ILE A 207
LEU A  67
 None
 1.12A 4j24B-1agxA:
0.0		 4j24B-1agxA:
24.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K50_I_ACTI507_0
(RNA POLYMERASE
3D-POL)		 1agx GLUTAMINASE-ASPARAGI
NASE
(Acinetobacter
glutaminasifican
s) 		3 / 3 LYS A  80
PRO A  81
SER A  82
 None
 0.39A 4k50I-1agxA:
0.0		 4k50I-1agxA:
23.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KT0_A_PQNA2001_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1
PHOTOSYSTEM I
REACTION CENTER
SUBUNIT IX)		 1agx GLUTAMINASE-ASPARAGI
NASE
(Acinetobacter
glutaminasifican
s) 		5 / 11 GLY A 179
ALA A 159
GLY A 182
ILE A   6
LEU A  36
 None
 1.03A 4kt0A-1agxA:
undetectable
4kt0J-1agxA:
0.0		 4kt0A-1agxA:
19.65
4kt0J-1agxA:
8.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Q5M_A_ROCA1101_1
(PROTEASE)		 1agx GLUTAMINASE-ASPARAGI
NASE
(Acinetobacter
glutaminasifican
s) 		5 / 12 GLY A  51
ILE A  13
ILE A  88
VAL A  74
ILE A 112
 None
 0.88A 4q5mA-1agxA:
undetectable		 4q5mA-1agxA:
19.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1A_C_CHDC304_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 1agx GLUTAMINASE-ASPARAGI
NASE
(Acinetobacter
glutaminasifican
s) 		4 / 7 LEU A 313
PHE A 205
LEU A 104
PHE A 100
 None
 0.92A 5b1aC-1agxA:
undetectable
5b1aJ-1agxA:
0.0		 5b1aC-1agxA:
21.25
5b1aJ-1agxA:
11.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1A_P_CHDP305_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 1agx GLUTAMINASE-ASPARAGI
NASE
(Acinetobacter
glutaminasifican
s) 		4 / 7 LEU A 313
PHE A 205
LEU A 104
PHE A 100
 None
 0.94A 5b1aP-1agxA:
undetectable
5b1aW-1agxA:
0.0		 5b1aP-1agxA:
21.25
5b1aW-1agxA:
11.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IY5_C_CHDC307_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 1agx GLUTAMINASE-ASPARAGI
NASE
(Acinetobacter
glutaminasifican
s) 		4 / 7 LEU A 313
PHE A 205
LEU A 104
PHE A 100
 None
 0.94A 5iy5C-1agxA:
undetectable
5iy5J-1agxA:
0.0		 5iy5C-1agxA:
21.37
5iy5J-1agxA:
11.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X19_C_CHDC304_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 1agx GLUTAMINASE-ASPARAGI
NASE
(Acinetobacter
glutaminasifican
s) 		4 / 5 LEU A 313
PHE A 205
LEU A 104
PHE A 100
 None
 0.94A 5x19C-1agxA:
undetectable
5x19J-1agxA:
0.0		 5x19C-1agxA:
21.25
5x19J-1agxA:
11.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z84_C_CHDC307_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 1agx GLUTAMINASE-ASPARAGI
NASE
(Acinetobacter
glutaminasifican
s) 		4 / 7 LEU A 313
PHE A 205
LEU A 104
PHE A 100
 None
 0.84A 5z84C-1agxA:
undetectable
5z84J-1agxA:
0.0		 5z84C-1agxA:
21.25
5z84J-1agxA:
11.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZW4_A_SAMA302_0
(PUTATIVE
O-METHYLTRANSFERASE
YRRM)		 1agx GLUTAMINASE-ASPARAGI
NASE
(Acinetobacter
glutaminasifican
s) 		5 / 12 GLY A  15
ALA A  28
TYR A  26
ALA A  35
ALA A   8
 None
 1.05A 5zw4A-1agxA:
undetectable		 5zw4A-1agxA:
21.05