SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1ahs'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T85_A_CAMA422_0
(CYTOCHROME P450-CAM)		 1ahs AFRICAN HORSE
SICKNESS VIRUS
(SEROTYPE 4) VP7
(African
horse
sickness
virus) 		4 / 7 THR A 126
VAL A 247
VAL A 182
ASP A 180
 None
 1.02A 1t85A-1ahsA:
undetectable		 1t85A-1ahsA:
14.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T87_A_CAMA1422_0
(CYTOCHROME P450-CAM)		 1ahs AFRICAN HORSE
SICKNESS VIRUS
(SEROTYPE 4) VP7
(African
horse
sickness
virus) 		4 / 7 THR A 126
VAL A 247
VAL A 182
ASP A 180
 None
 1.04A 1t87A-1ahsA:
0.0		 1t87A-1ahsA:
14.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YRC_A_CAMA420_0
(CYTOCHROME P450-CAM)		 1ahs AFRICAN HORSE
SICKNESS VIRUS
(SEROTYPE 4) VP7
(African
horse
sickness
virus) 		4 / 7 THR A 126
VAL A 247
VAL A 182
ASP A 180
 None
 1.01A 1yrcA-1ahsA:
0.0		 1yrcA-1ahsA:
14.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YRD_A_CAMA420_0
(CYTOCHROME P450-CAM)		 1ahs AFRICAN HORSE
SICKNESS VIRUS
(SEROTYPE 4) VP7
(African
horse
sickness
virus) 		4 / 7 THR A 126
VAL A 247
VAL A 182
ASP A 180
 None
 1.01A 1yrdA-1ahsA:
undetectable		 1yrdA-1ahsA:
14.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FEU_B_CAMB1421_0
(CYTOCHROME P450-CAM)		 1ahs AFRICAN HORSE
SICKNESS VIRUS
(SEROTYPE 4) VP7
(African
horse
sickness
virus) 		4 / 7 THR A 126
VAL A 247
VAL A 182
ASP A 180
 None
 1.00A 2feuB-1ahsA:
undetectable		 2feuB-1ahsA:
14.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PLW_A_SAMA203_0
(RIBOSOMAL RNA
METHYLTRANSFERASE,
PUTATIVE)		 1ahs AFRICAN HORSE
SICKNESS VIRUS
(SEROTYPE 4) VP7
(African
horse
sickness
virus) 		5 / 12 GLY A 131
TYR A 129
PRO A 128
GLY A 127
GLU A 134
 None
 0.99A 2plwA-1ahsA:
undetectable		 2plwA-1ahsA:
18.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QHF_A_ACTA509_0
(CHORISMATE SYNTHASE)		 1ahs AFRICAN HORSE
SICKNESS VIRUS
(SEROTYPE 4) VP7
(African
horse
sickness
virus) 		3 / 3 ARG A 240
GLN A 198
PRO A 197
 None
 0.85A 2qhfA-1ahsA:
0.2		 2qhfA-1ahsA:
15.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZWT_A_CAMA422_0
(CAMPHOR
5-MONOOXYGENASE)		 1ahs AFRICAN HORSE
SICKNESS VIRUS
(SEROTYPE 4) VP7
(African
horse
sickness
virus) 		4 / 7 THR A 126
VAL A 247
VAL A 182
ASP A 180
 None
 1.00A 2zwtA-1ahsA:
undetectable		 2zwtA-1ahsA:
14.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZWU_A_CAMA422_0
(CAMPHOR
5-MONOOXYGENASE)		 1ahs AFRICAN HORSE
SICKNESS VIRUS
(SEROTYPE 4) VP7
(African
horse
sickness
virus) 		4 / 7 THR A 126
VAL A 247
VAL A 182
ASP A 180
 None
 1.01A 2zwuA-1ahsA:
undetectable		 2zwuA-1ahsA:
14.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D4S_A_TIMA401_1
(BETA-2 ADRENERGIC
RECEPTOR/T4-LYSOZYME
CHIMERA)		 1ahs AFRICAN HORSE
SICKNESS VIRUS
(SEROTYPE 4) VP7
(African
horse
sickness
virus) 		5 / 12 VAL A 170
VAL A 231
TRP A 225
PHE A 186
TYR A 129
 None
 1.19A 3d4sA-1ahsA:
undetectable		 3d4sA-1ahsA:
12.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FWF_A_CAMA420_0
(CAMPHOR
5-MONOOXYGENASE)		 1ahs AFRICAN HORSE
SICKNESS VIRUS
(SEROTYPE 4) VP7
(African
horse
sickness
virus) 		4 / 7 THR A 126
VAL A 247
VAL A 182
ASP A 180
 None
 1.00A 3fwfA-1ahsA:
0.0		 3fwfA-1ahsA:
15.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FWF_B_CAMB420_0
(CAMPHOR
5-MONOOXYGENASE)		 1ahs AFRICAN HORSE
SICKNESS VIRUS
(SEROTYPE 4) VP7
(African
horse
sickness
virus) 		4 / 7 THR A 126
VAL A 247
VAL A 182
ASP A 180
 None
 0.97A 3fwfB-1ahsA:
undetectable		 3fwfB-1ahsA:
15.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FWJ_A_CAMA420_0
(CAMPHOR
5-MONOOXYGENASE)		 1ahs AFRICAN HORSE
SICKNESS VIRUS
(SEROTYPE 4) VP7
(African
horse
sickness
virus) 		4 / 7 THR A 126
VAL A 247
VAL A 182
ASP A 180
 None
 1.02A 3fwjA-1ahsA:
undetectable		 3fwjA-1ahsA:
15.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3L63_A_CAMA440_0
(CAMPHOR
5-MONOOXYGENASE)		 1ahs AFRICAN HORSE
SICKNESS VIRUS
(SEROTYPE 4) VP7
(African
horse
sickness
virus) 		4 / 7 THR A 126
VAL A 247
VAL A 182
ASP A 180
 None
 0.96A 3l63A-1ahsA:
undetectable		 3l63A-1ahsA:
14.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WRH_A_CAMA503_0
(CAMPHOR
5-MONOOXYGENASE)		 1ahs AFRICAN HORSE
SICKNESS VIRUS
(SEROTYPE 4) VP7
(African
horse
sickness
virus) 		4 / 7 THR A 126
VAL A 247
VAL A 182
ASP A 180
 None
 0.98A 3wrhA-1ahsA:
undetectable		 3wrhA-1ahsA:
14.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WRJ_A_CAMA503_0
(CAMPHOR
5-MONOOXYGENASE)		 1ahs AFRICAN HORSE
SICKNESS VIRUS
(SEROTYPE 4) VP7
(African
horse
sickness
virus) 		4 / 7 THR A 126
VAL A 247
VAL A 182
ASP A 180
 None
 0.99A 3wrjA-1ahsA:
undetectable		 3wrjA-1ahsA:
14.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WRL_A_CAMA503_0
(CAMPHOR
5-MONOOXYGENASE)		 1ahs AFRICAN HORSE
SICKNESS VIRUS
(SEROTYPE 4) VP7
(African
horse
sickness
virus) 		4 / 7 THR A 126
VAL A 247
VAL A 182
ASP A 180
 None
 0.98A 3wrlA-1ahsA:
0.0		 3wrlA-1ahsA:
14.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WRL_E_CAME503_0
(CAMPHOR
5-MONOOXYGENASE)		 1ahs AFRICAN HORSE
SICKNESS VIRUS
(SEROTYPE 4) VP7
(African
horse
sickness
virus) 		4 / 7 THR A 126
VAL A 247
VAL A 182
ASP A 180
 None
 0.99A 3wrlE-1ahsA:
0.0		 3wrlE-1ahsA:
14.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WRM_A_CAMA503_0
(CAMPHOR
5-MONOOXYGENASE)		 1ahs AFRICAN HORSE
SICKNESS VIRUS
(SEROTYPE 4) VP7
(African
horse
sickness
virus) 		4 / 7 THR A 126
VAL A 247
VAL A 182
ASP A 180
 None
 1.00A 3wrmA-1ahsA:
undetectable		 3wrmA-1ahsA:
14.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WRM_F_CAMF503_0
(CAMPHOR
5-MONOOXYGENASE)		 1ahs AFRICAN HORSE
SICKNESS VIRUS
(SEROTYPE 4) VP7
(African
horse
sickness
virus) 		4 / 7 THR A 126
VAL A 247
VAL A 182
ASP A 180
 None
 0.96A 3wrmF-1ahsA:
undetectable		 3wrmF-1ahsA:
14.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L4G_A_CAMA503_0
(CAMPHOR
5-MONOOXYGENASE)		 1ahs AFRICAN HORSE
SICKNESS VIRUS
(SEROTYPE 4) VP7
(African
horse
sickness
virus) 		4 / 7 THR A 126
VAL A 247
VAL A 182
ASP A 180
 None
 1.02A 4l4gA-1ahsA:
0.0		 4l4gA-1ahsA:
14.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V32_C_EF2C151_1
(CEREBLON ISOFORM 4)		 1ahs AFRICAN HORSE
SICKNESS VIRUS
(SEROTYPE 4) VP7
(African
horse
sickness
virus) 		4 / 7 ASN A 235
PHE A 209
TRP A 188
PHE A 245
 None
 1.37A 4v32C-1ahsA:
undetectable		 4v32C-1ahsA:
27.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DL9_A_ACTA214_0
(LYSOZYME C)		 1ahs AFRICAN HORSE
SICKNESS VIRUS
(SEROTYPE 4) VP7
(African
horse
sickness
virus) 		4 / 5 ASP A 213
TRP A 225
VAL A 223
ALA A 224
 None
 1.43A 5dl9A-1ahsA:
undetectable		 5dl9A-1ahsA:
20.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WK9_A_CAMA503_0
(CAMPHOR
5-MONOOXYGENASE)		 1ahs AFRICAN HORSE
SICKNESS VIRUS
(SEROTYPE 4) VP7
(African
horse
sickness
virus) 		4 / 7 THR A 126
VAL A 247
VAL A 182
ASP A 180
 None
 1.02A 5wk9A-1ahsA:
undetectable		 5wk9A-1ahsA:
14.63