SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1aih'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HZ4_A_BEZA784_0
(MALT REGULATORY
PROTEIN)		 1aih HP1 INTEGRASE
(Haemophilus
virus
HP1) 		4 / 6 HIS A 280
LEU A 278
LEU A 273
PRO A 274
 None
 1.31A 1hz4A-1aihA:
undetectable		 1hz4A-1aihA:
20.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V54_W_CHDW4060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I
CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART)		 1aih HP1 INTEGRASE
(Haemophilus
virus
HP1) 		4 / 7 ILE A 239
LEU A 243
THR A 215
LEU A 214
 None
None
SO4  A 109 (-4.1A)
None
 1.00A 1v54N-1aihA:
0.0
1v54W-1aihA:
0.1		 1v54N-1aihA:
15.90
1v54W-1aihA:
17.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V55_W_CHDW4060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I
CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART)		 1aih HP1 INTEGRASE
(Haemophilus
virus
HP1) 		4 / 8 ILE A 239
LEU A 243
THR A 215
LEU A 214
 None
None
SO4  A 109 (-4.1A)
None
 0.93A 1v55N-1aihA:
0.0
1v55W-1aihA:
0.1		 1v55N-1aihA:
15.90
1v55W-1aihA:
17.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYR_W_CHDW1060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)		 1aih HP1 INTEGRASE
(Haemophilus
virus
HP1) 		4 / 7 ILE A 239
LEU A 243
THR A 215
LEU A 214
 None
None
SO4  A 109 (-4.1A)
None
 0.98A 2dyrN-1aihA:
undetectable
2dyrW-1aihA:
0.0		 2dyrN-1aihA:
15.90
2dyrW-1aihA:
17.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIJ_W_CHDW1060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)		 1aih HP1 INTEGRASE
(Haemophilus
virus
HP1) 		4 / 8 ILE A 239
LEU A 243
THR A 215
LEU A 214
 None
None
SO4  A 109 (-4.1A)
None
 0.92A 2eijN-1aihA:
undetectable
2eijW-1aihA:
0.0		 2eijN-1aihA:
15.90
2eijW-1aihA:
17.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIK_W_CHDW1060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)		 1aih HP1 INTEGRASE
(Haemophilus
virus
HP1) 		4 / 8 ILE A 239
LEU A 243
THR A 215
LEU A 214
 None
None
SO4  A 109 (-4.1A)
None
 0.88A 2eikN-1aihA:
0.0
2eikW-1aihA:
0.0		 2eikN-1aihA:
15.90
2eikW-1aihA:
17.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIL_W_CHDW1060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)		 1aih HP1 INTEGRASE
(Haemophilus
virus
HP1) 		4 / 8 ILE A 239
LEU A 243
THR A 215
LEU A 214
 None
None
SO4  A 109 (-4.1A)
None
 0.89A 2eilN-1aihA:
0.0
2eilW-1aihA:
0.0		 2eilN-1aihA:
15.90
2eilW-1aihA:
17.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABL_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)		 1aih HP1 INTEGRASE
(Haemophilus
virus
HP1) 		4 / 7 ILE A 239
LEU A 243
THR A 215
LEU A 214
 None
None
SO4  A 109 (-4.1A)
None
 1.07A 3ablA-1aihA:
undetectable
3ablJ-1aihA:
0.1		 3ablA-1aihA:
15.90
3ablJ-1aihA:
17.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABL_W_CHDW1060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)		 1aih HP1 INTEGRASE
(Haemophilus
virus
HP1) 		4 / 8 ILE A 239
LEU A 243
THR A 215
LEU A 214
 None
None
SO4  A 109 (-4.1A)
None
 0.92A 3ablN-1aihA:
0.0
3ablW-1aihA:
0.1		 3ablN-1aihA:
15.90
3ablW-1aihA:
17.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABM_W_CHDW1060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)		 1aih HP1 INTEGRASE
(Haemophilus
virus
HP1) 		4 / 8 ILE A 239
LEU A 243
THR A 215
LEU A 214
 None
None
SO4  A 109 (-4.1A)
None
 0.91A 3abmN-1aihA:
undetectable
3abmW-1aihA:
0.0		 3abmN-1aihA:
15.90
3abmW-1aihA:
17.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EAH_F_ACTF402_0
(ACTIN, ALPHA
SKELETAL MUSCLE)		 1aih HP1 INTEGRASE
(Haemophilus
virus
HP1) 		3 / 3 PHE A 255
ASP A 257
ARG A 253
 None
 0.80A 4eahF-1aihA:
0.0		 4eahF-1aihA:
20.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EAH_G_ACTG401_0
(ACTIN, ALPHA
SKELETAL MUSCLE)		 1aih HP1 INTEGRASE
(Haemophilus
virus
HP1) 		3 / 3 PHE A 255
ASP A 257
ARG A 253
 None
 0.80A 4eahG-1aihA:
undetectable		 4eahG-1aihA:
20.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y2T_B_8LXB501_0
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 1aih HP1 INTEGRASE
(Haemophilus
virus
HP1) 		5 / 12 ILE A 239
ILE A 179
TYR A 180
LEU A 183
ILE A 200
 None
 1.05A 5y2tB-1aihA:
undetectable		 5y2tB-1aihA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NMP_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 1aih HP1 INTEGRASE
(Haemophilus
virus
HP1) 		4 / 7 ILE A 239
LEU A 243
THR A 215
LEU A 214
 None
None
SO4  A 109 (-4.1A)
None
 0.93A 6nmpA-1aihA:
0.0
6nmpJ-1aihA:
0.0		 6nmpA-1aihA:
15.90
6nmpJ-1aihA:
17.31