SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1aip'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T87_B_CAMB2422_0
(CYTOCHROME P450-CAM)		 1aip ELONGATION FACTOR TS
(Thermus
thermophilus) 		4 / 7 LEU C 157
VAL C 169
VAL C  74
ILE C 100
 None
 0.98A 1t87B-1aipC:
0.0		 1t87B-1aipC:
18.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WD9_A_IBPA1570_1
(ACYL-COENZYME A
SYNTHETASE ACSM2A,
MITOCHONDRIAL)		 1aip ELONGATION FACTOR TS
(Thermus
thermophilus) 		4 / 7 ILE C   7
LEU C  10
GLY C  15
GLY C  17
 None
 0.66A 2wd9A-1aipC:
undetectable		 2wd9A-1aipC:
15.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WD9_B_IBPB1570_1
(ACYL-COENZYME A
SYNTHETASE ACSM2A,
MITOCHONDRIAL)		 1aip ELONGATION FACTOR TS
(Thermus
thermophilus) 		4 / 8 ILE C   7
LEU C  10
GLY C  15
GLY C  17
 None
 0.65A 2wd9B-1aipC:
undetectable		 2wd9B-1aipC:
15.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D1Z_B_017B201_2
(HIV-1 PROTEASE)		 1aip ELONGATION FACTOR TS
(Thermus
thermophilus) 		5 / 12 GLY C  15
ALA C  16
ASP C  20
GLY C 181
ILE C 180
 None
 0.99A 3d1zB-1aipC:
undetectable		 3d1zB-1aipC:
18.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S53_A_017A201_1
(PROTEASE)		 1aip ELONGATION FACTOR TS
(Thermus
thermophilus) 		5 / 9 GLY C  15
ALA C  16
ASP C  20
GLY C 181
ILE C 180
 None
 0.99A 3s53A-1aipC:
undetectable		 3s53A-1aipC:
18.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SO9_A_017A100_1
(HIV-1 PROTEASE)		 1aip ELONGATION FACTOR TS
(Thermus
thermophilus) 		5 / 8 GLY C  15
ALA C  16
ASP C  20
GLY C 181
ILE C 180
 None
 0.97A 3so9A-1aipC:
0.0		 3so9A-1aipC:
19.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U7S_A_017A201_1
(POL POLYPROTEIN)		 1aip ELONGATION FACTOR TS
(Thermus
thermophilus) 		5 / 9 GLY C  15
ALA C  16
ASP C  20
GLY C 181
ILE C 180
 None
 0.93A 3u7sA-1aipC:
undetectable		 3u7sA-1aipC:
17.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AE1_A_NCAA1536_0
(DIPHTHERIA TOXIN)		 1aip ELONGATION FACTOR TS
(Thermus
thermophilus) 		4 / 6 GLY C 145
TYR C 150
ALA C 143
GLU C 121
 None
 0.98A 4ae1A-1aipC:
undetectable		 4ae1A-1aipC:
16.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DQC_A_017A101_2
(ASPARTYL PROTEASE)		 1aip ELONGATION FACTOR TS
(Thermus
thermophilus) 		5 / 9 GLY C  15
ALA C  16
ASP C  20
GLY C 181
ILE C 180
 None
 1.04A 4dqcB-1aipC:
undetectable		 4dqcB-1aipC:
18.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NJT_B_017B101_2
(PROTEASE)		 1aip ELONGATION FACTOR TS
(Thermus
thermophilus) 		5 / 10 GLY C  15
ALA C  16
ASP C  20
GLY C 181
ILE C 180
 None
 0.98A 4njtB-1aipC:
undetectable		 4njtB-1aipC:
19.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Q1W_A_017A104_1
(ASPARTYL PROTEASE)		 1aip ELONGATION FACTOR TS
(Thermus
thermophilus) 		5 / 9 GLY C  15
ALA C  16
ASP C  20
GLY C 181
ILE C 180
 None
 1.00A 4q1wA-1aipC:
undetectable		 4q1wA-1aipC:
19.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KR0_A_478A101_2
(PROTEASE E35D-APV)		 1aip ELONGATION FACTOR TS
(Thermus
thermophilus) 		5 / 9 GLY C  15
ALA C  16
ASP C  20
GLY C 181
ILE C 180
 None
 1.02A 5kr0B-1aipC:
undetectable		 5kr0B-1aipC:
17.26