SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1ajk'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_B_TRPB81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 1ajk CIRCULARLY PERMUTED
(1-3,1-4)-BETA-D-GLU
CAN
4-GLUCANOHYDROLASE
(Paenibacillus
macerans) 		4 / 8 SER A  58
ALA A 213
THR A  32
ILE A   4
 None
 0.79A 1gtnA-1ajkA:
0.1
1gtnB-1ajkA:
0.0		 1gtnA-1ajkA:
16.82
1gtnB-1ajkA:
16.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_P_TRPP81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 1ajk CIRCULARLY PERMUTED
(1-3,1-4)-BETA-D-GLU
CAN
4-GLUCANOHYDROLASE
(Paenibacillus
macerans) 		4 / 8 ALA A 213
THR A  32
ILE A   4
SER A  58
 None
 0.81A 1gtnP-1ajkA:
0.0
1gtnQ-1ajkA:
0.0		 1gtnP-1ajkA:
16.82
1gtnQ-1ajkA:
16.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1R15_C_NCAC439_0
(ADP-RIBOSYL CYCLASE)		 1ajk CIRCULARLY PERMUTED
(1-3,1-4)-BETA-D-GLU
CAN
4-GLUCANOHYDROLASE
(Paenibacillus
macerans) 		3 / 3 TRP A 165
PHE A 161
TRP A 101
 None
EPE  A 309 ( 4.9A)
EPE  A 309 (-4.1A)
 1.48A 1r15C-1ajkA:
0.0		 1r15C-1ajkA:
22.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1R15_F_NCAF469_0
(ADP-RIBOSYL CYCLASE)		 1ajk CIRCULARLY PERMUTED
(1-3,1-4)-BETA-D-GLU
CAN
4-GLUCANOHYDROLASE
(Paenibacillus
macerans) 		3 / 3 TRP A 165
PHE A 161
TRP A 101
 None
EPE  A 309 ( 4.9A)
EPE  A 309 (-4.1A)
 1.49A 1r15F-1ajkA:
0.0		 1r15F-1ajkA:
22.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1R15_G_NCAG479_0
(ADP-RIBOSYL CYCLASE)		 1ajk CIRCULARLY PERMUTED
(1-3,1-4)-BETA-D-GLU
CAN
4-GLUCANOHYDROLASE
(Paenibacillus
macerans) 		3 / 3 TRP A 165
PHE A 161
TRP A 101
 None
EPE  A 309 ( 4.9A)
EPE  A 309 (-4.1A)
 1.49A 1r15G-1ajkA:
0.0		 1r15G-1ajkA:
22.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1R15_H_NCAH489_0
(ADP-RIBOSYL CYCLASE)		 1ajk CIRCULARLY PERMUTED
(1-3,1-4)-BETA-D-GLU
CAN
4-GLUCANOHYDROLASE
(Paenibacillus
macerans) 		3 / 3 TRP A 165
PHE A 161
TRP A 101
 None
EPE  A 309 ( 4.9A)
EPE  A 309 (-4.1A)
 1.49A 1r15H-1ajkA:
0.0		 1r15H-1ajkA:
22.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_B_TRPB81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1ajk CIRCULARLY PERMUTED
(1-3,1-4)-BETA-D-GLU
CAN
4-GLUCANOHYDROLASE
(Paenibacillus
macerans) 		4 / 8 ALA A 213
THR A  32
ILE A   4
SER A  58
 None
 0.76A 1utdB-1ajkA:
0.3
1utdC-1ajkA:
0.1		 1utdB-1ajkA:
16.82
1utdC-1ajkA:
16.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_F_TRPF81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1ajk CIRCULARLY PERMUTED
(1-3,1-4)-BETA-D-GLU
CAN
4-GLUCANOHYDROLASE
(Paenibacillus
macerans) 		4 / 8 ALA A 213
THR A  32
ILE A   4
SER A  58
 None
 0.79A 1utdF-1ajkA:
0.1
1utdG-1ajkA:
0.0		 1utdF-1ajkA:
16.82
1utdG-1ajkA:
16.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_J_TRPJ81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1ajk CIRCULARLY PERMUTED
(1-3,1-4)-BETA-D-GLU
CAN
4-GLUCANOHYDROLASE
(Paenibacillus
macerans) 		4 / 8 ALA A 213
THR A  32
ILE A   4
SER A  58
 None
 0.78A 1utdJ-1ajkA:
0.0
1utdK-1ajkA:
0.3		 1utdJ-1ajkA:
16.82
1utdK-1ajkA:
16.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PGZ_D_COCD401_1
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)		 1ajk CIRCULARLY PERMUTED
(1-3,1-4)-BETA-D-GLU
CAN
4-GLUCANOHYDROLASE
(Paenibacillus
macerans) 		4 / 6 TRP A  75
TYR A  72
TYR A  39
ILE A  23
 None
 1.11A 2pgzD-1ajkA:
0.0
2pgzE-1ajkA:
0.6		 2pgzD-1ajkA:
23.29
2pgzE-1ajkA:
23.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X2N_A_X2NA1480_1
(LANOSTEROL
14-ALPHA-DEMETHYLASE)		 1ajk CIRCULARLY PERMUTED
(1-3,1-4)-BETA-D-GLU
CAN
4-GLUCANOHYDROLASE
(Paenibacillus
macerans) 		5 / 12 PHE A  27
PHE A  37
ALA A 213
ALA A  65
MET A 210
 None
 0.96A 2x2nA-1ajkA:
undetectable		 2x2nA-1ajkA:
15.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CSW_A_P06A801_2
(SERINE/THREONINE-PRO
TEIN KINASE B-RAF)		 1ajk CIRCULARLY PERMUTED
(1-3,1-4)-BETA-D-GLU
CAN
4-GLUCANOHYDROLASE
(Paenibacillus
macerans) 		3 / 3 PHE A  66
ILE A  25
ASP A  78
 None
 0.74A 5cswA-1ajkA:
0.0		 5cswA-1ajkA:
21.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CSW_B_P06B801_2
(SERINE/THREONINE-PRO
TEIN KINASE B-RAF)		 1ajk CIRCULARLY PERMUTED
(1-3,1-4)-BETA-D-GLU
CAN
4-GLUCANOHYDROLASE
(Paenibacillus
macerans) 		3 / 3 PHE A  66
ILE A  25
ASP A  78
 None
 0.70A 5cswB-1ajkA:
0.0		 5cswB-1ajkA:
21.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5D0Y_A_FOLA201_0
(CONSERVED
HYPOTHETICAL
MEMBRANE PROTEIN)		 1ajk CIRCULARLY PERMUTED
(1-3,1-4)-BETA-D-GLU
CAN
4-GLUCANOHYDROLASE
(Paenibacillus
macerans) 		5 / 12 GLY A 158
ASP A 191
PHE A 190
THR A 183
ASN A 102
 None
 1.19A 5d0yA-1ajkA:
undetectable		 5d0yA-1ajkA:
19.83