SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1akp'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JG4_A_SAMA500_0
(PROTEIN-L-ISOASPARTA
TE
O-METHYLTRANSFERASE)		 1akp APOKEDARCIDIN
(actinomycete
ATCC
53650) 		5 / 12 VAL A  98
GLY A 100
GLY A  60
ALA A  23
VAL A   5
 None
 1.11A 1jg4A-1akpA:
undetectable		 1jg4A-1akpA:
17.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_G_FUAG708_2
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 1akp APOKEDARCIDIN
(actinomycete
ATCC
53650) 		3 / 3 VAL A  99
ALA A  34
HIS A  53
 None
 0.75A 1q23H-1akpA:
undetectable		 1q23H-1akpA:
17.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RET_B_SALB201_1
(SALICYLATE
BIOSYNTHESIS PROTEIN
PCHB)		 1akp APOKEDARCIDIN
(actinomycete
ATCC
53650) 		5 / 9 VAL A  68
ALA A  34
VAL A  21
ILE A  97
GLN A  36
 None
 1.27A 3retB-1akpA:
undetectable		 3retB-1akpA:
23.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M93_B_ACTB303_0
(S25-26 FAB (IGG1K)
HEAVY CHAIN
S25-26 FAB (IGG1K)
LIGHT CHAIN)		 1akp APOKEDARCIDIN
(actinomycete
ATCC
53650) 		4 / 5 GLY A  25
SER A  24
ALA A  23
PHE A  26
 None
 0.87A 4m93B-1akpA:
4.5
4m93C-1akpA:
4.1		 4m93B-1akpA:
17.35
4m93C-1akpA:
18.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW0_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA TYPE-5)		 1akp APOKEDARCIDIN
(actinomycete
ATCC
53650) 		4 / 7 ALA A  34
THR A  33
ALA A  32
THR A  64
 None
 0.76A 4qw0K-1akpA:
undetectable		 4qw0K-1akpA:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW0_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA TYPE-5)		 1akp APOKEDARCIDIN
(actinomycete
ATCC
53650) 		4 / 7 ALA A  34
THR A  33
ALA A  32
THR A  64
 None
 0.75A 4qw0Y-1akpA:
undetectable		 4qw0Y-1akpA:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R29_D_SAMD301_0
(UNCHARACTERIZED
PROTEIN)		 1akp APOKEDARCIDIN
(actinomycete
ATCC
53650) 		5 / 12 SER A  29
GLY A 101
ILE A  97
ALA A 109
GLY A 107
 None
 1.10A 4r29D-1akpA:
0.0		 4r29D-1akpA:
19.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WNW_B_RTZB602_2
(CYTOCHROME P450 2D6)		 1akp APOKEDARCIDIN
(actinomycete
ATCC
53650) 		3 / 3 GLU A  51
ILE A 111
ALA A  34
 None
 0.67A 4wnwB-1akpA:
undetectable		 4wnwB-1akpA:
12.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XNX_A_41XA707_1
(TRANSPORTER)		 1akp APOKEDARCIDIN
(actinomycete
ATCC
53650) 		5 / 11 ALA A  23
VAL A   5
GLY A 101
SER A   2
GLY A  25
 None
 1.24A 4xnxA-1akpA:
undetectable		 4xnxA-1akpA:
13.68