SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1alq'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1GHM_A_CEDA1_1
(BETA-LACTAMASE)		 1alq CP254 BETA-LACTAMASE
(Staphylococcus
aureus) 		10 / 12 ALA A  69
SER A  70
LYS A  73
SER A 130
ASN A 132
ILE A 167
LYS A 234
SER A 235
GLY A 236
ARG A 244
 None
 0.34A 1ghmA-1alqA:
35.2		 1ghmA-1alqA:
82.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1I2W_A_CFXA1300_1
(BETA-LACTAMASE)		 1alq CP254 BETA-LACTAMASE
(Staphylococcus
aureus) 		8 / 12 ALA A  69
SER A  70
LYS A  73
SER A 130
ASN A 132
GLU A 166
LYS A 234
GLY A 236
 None
 0.38A 1i2wA-1alqA:
30.1		 1i2wA-1alqA:
35.62
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1I2W_B_CFXB2300_1
(BETA-LACTAMASE)		 1alq CP254 BETA-LACTAMASE
(Staphylococcus
aureus) 		6 / 12 ALA A  69
SER A  70
LYS A  73
ASN A 132
GLU A 166
ALA A 238
 None
 1.37A 1i2wB-1alqA:
24.4		 1i2wB-1alqA:
35.62
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1I2W_B_CFXB2300_1
(BETA-LACTAMASE)		 1alq CP254 BETA-LACTAMASE
(Staphylococcus
aureus) 		8 / 12 ALA A  69
SER A  70
LYS A  73
SER A 130
ASN A 132
GLU A 166
GLY A 236
ARG A 244
 None
 0.39A 1i2wB-1alqA:
24.4		 1i2wB-1alqA:
35.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TW4_A_CHDA130_0
(FATTY ACID-BINDING
PROTEIN)		 1alq CP254 BETA-LACTAMASE
(Staphylococcus
aureus) 		5 / 12 LEU A 193
LEU A 190
LEU A 152
ILE A 142
LEU A 207
 None
 1.03A 1tw4A-1alqA:
undetectable		 1tw4A-1alqA:
18.08
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1YMX_A_CFXA1001_1
(BETA-LACTAMASE
CTX-M-9)		 1alq CP254 BETA-LACTAMASE
(Staphylococcus
aureus) 		8 / 12 SER A  70
LYS A  73
SER A 130
ASN A 132
GLU A 166
ASN A 170
LYS A 234
GLY A 236
 None
 0.59A 1ymxA-1alqA:
28.2		 1ymxA-1alqA:
30.41
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1YMX_B_CFXB1002_1
(BETA-LACTAMASE
CTX-M-9)		 1alq CP254 BETA-LACTAMASE
(Staphylococcus
aureus) 		8 / 12 SER A  70
LYS A  73
SER A 130
ASN A 132
GLU A 166
ASN A 170
LYS A 234
GLY A 236
 None
 0.56A 1ymxB-1alqA:
28.2		 1ymxB-1alqA:
30.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AA6_A_STRA401_1
(MINERALOCORTICOID
RECEPTOR)		 1alq CP254 BETA-LACTAMASE
(Staphylococcus
aureus) 		5 / 12 LEU A 190
ASN A 191
LEU A 193
LEU A 207
MET A 211
 None
 1.36A 2aa6A-1alqA:
undetectable		 2aa6A-1alqA:
22.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BRF_A_SORA2_0
(LIN-12 AND GLP-1
PHENOTYPE PROTEIN 1,
ISOFORM A)		 1alq CP254 BETA-LACTAMASE
(Staphylococcus
aureus) 		3 / 3 LYS A  99
LYS A 111
VAL A 113
 None
 1.03A 3brfA-1alqA:
undetectable		 3brfA-1alqA:
20.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3HLW_A_CE3A301_1
(CTX-M-9
EXTENDED-SPECTRUM
BETA-LACTAMASE)		 1alq CP254 BETA-LACTAMASE
(Staphylococcus
aureus) 		7 / 12 LYS A  73
TYR A 105
SER A 130
ASN A 132
ASN A 170
LYS A 234
GLY A 236
 None
 0.65A 3hlwA-1alqA:
15.2		 3hlwA-1alqA:
30.07
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3HLW_B_CE3B302_1
(CTX-M-9
EXTENDED-SPECTRUM
BETA-LACTAMASE)		 1alq CP254 BETA-LACTAMASE
(Staphylococcus
aureus) 		6 / 12 TYR A 105
SER A 130
ASN A 132
ASN A 170
LYS A 234
GLY A 236
 None
 0.66A 3hlwB-1alqA:
28.0		 3hlwB-1alqA:
30.07
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3HUO_A_PNNA300_0
(CTX-M-9
EXTENDED-SPECTRUM
BETA-LACTAMASE)		 1alq CP254 BETA-LACTAMASE
(Staphylococcus
aureus) 		5 / 12 LYS A  73
ASN A 132
ASN A 170
LYS A 234
GLY A 236
 None
 0.57A 3huoA-1alqA:
28.1		 3huoA-1alqA:
30.07
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3HUO_B_PNNB301_0
(CTX-M-9
EXTENDED-SPECTRUM
BETA-LACTAMASE)		 1alq CP254 BETA-LACTAMASE
(Staphylococcus
aureus) 		5 / 12 LYS A  73
ASN A 132
ASN A 170
LYS A 234
GLY A 236
 None
 0.53A 3huoB-1alqA:
28.2		 3huoB-1alqA:
30.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MZE_A_CFXA364_1
(D-ALANYL-D-ALANINE
CARBOXYPEPTIDASE
DACA)		 1alq CP254 BETA-LACTAMASE
(Staphylococcus
aureus) 		6 / 12 ALA A  69
SER A  70
LYS A  73
ASN A 132
GLY A 236
ARG A 244
 None
 0.80A 3mzeA-1alqA:
16.1		 3mzeA-1alqA:
20.65
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3Q07_A_WPPA300_1
(BETA-LACTAMASE)		 1alq CP254 BETA-LACTAMASE
(Staphylococcus
aureus) 		6 / 12 LYS A  73
SER A 130
ASN A 132
ASN A 170
LYS A 234
GLY A 236
 None
 0.57A 3q07A-1alqA:
28.1		 3q07A-1alqA:
30.07
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3Q07_B_WPPB400_1
(BETA-LACTAMASE)		 1alq CP254 BETA-LACTAMASE
(Staphylococcus
aureus) 		6 / 12 LYS A  73
SER A 130
ASN A 132
ASN A 170
LYS A 234
GLY A 236
 None
 0.51A 3q07B-1alqA:
28.2		 3q07B-1alqA:
30.07
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3SH8_A_CEDA1_1
(BETA-LACTAMASE)		 1alq CP254 BETA-LACTAMASE
(Staphylococcus
aureus) 		8 / 12 ALA A  69
SER A  70
TYR A 105
SER A 130
ASN A 132
LYS A 234
GLY A 236
ARG A 244
 None
 0.54A 3sh8A-1alqA:
28.3		 3sh8A-1alqA:
32.90
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3SH8_B_CEDB1_1
(BETA-LACTAMASE)		 1alq CP254 BETA-LACTAMASE
(Staphylococcus
aureus) 		8 / 12 ALA A  69
SER A  70
LYS A  73
SER A 130
ASN A 132
LYS A 234
GLY A 236
ARG A 244
 None
 0.56A 3sh8B-1alqA:
28.4		 3sh8B-1alqA:
32.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UWL_B_FOZB316_0
(THYMIDYLATE SYNTHASE)		 1alq CP254 BETA-LACTAMASE
(Staphylococcus
aureus) 		5 / 12 ILE A  75
GLY A 187
PHE A 186
ILE A 194
ALA A 195
 None
 0.88A 3uwlB-1alqA:
0.0		 3uwlB-1alqA:
20.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WXO_A_NIZA803_1
(CATALASE-PEROXIDASE)		 1alq CP254 BETA-LACTAMASE
(Staphylococcus
aureus) 		4 / 4 ASP A 246
THR A 219
VAL A 231
SER A 216
 None
 1.32A 3wxoA-1alqA:
0.0		 3wxoA-1alqA:
16.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AN2_A_EUIA1382_2
(DUAL SPECIFICITY
MITOGEN-ACTIVATED
PROTEIN KINASE
KINASE 1)		 1alq CP254 BETA-LACTAMASE
(Staphylococcus
aureus) 		4 / 4 ASN A 191
SER A 200
LEU A 199
THR A  51
 None
 1.47A 4an2A-1alqA:
0.0		 4an2A-1alqA:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EUZ_A_MEMA401_1
(CARBAPENEM-HYDROLIZI
NG BETA-LACTAMASE
SFC-1)		 1alq CP254 BETA-LACTAMASE
(Staphylococcus
aureus) 		6 / 12 LYS A  73
SER A 130
ASN A 132
ASN A 170
LYS A 234
GLY A 236
 None
 0.41A 4euzA-1alqA:
27.3		 4euzA-1alqA:
29.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FH2_A_0RNA303_1
(BETA-LACTAMASE SHV-1)		 1alq CP254 BETA-LACTAMASE
(Staphylococcus
aureus) 		6 / 10 TYR A 105
SER A 130
ASN A 132
LYS A 234
GLY A 236
ARG A 244
 None
 0.63A 4fh2A-1alqA:
25.8		 4fh2A-1alqA:
29.04
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4N9K_A_CEDA301_1
(BETA-LACTAMASE)		 1alq CP254 BETA-LACTAMASE
(Staphylococcus
aureus) 		9 / 12 ALA A  69
SER A  70
TYR A 105
SER A 130
ASN A 132
ASN A 170
LYS A 234
GLY A 236
ARG A 244
 None
 0.56A 4n9kA-1alqA:
24.2		 4n9kA-1alqA:
33.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4N9K_B_CEDB301_1
(BETA-LACTAMASE)		 1alq CP254 BETA-LACTAMASE
(Staphylococcus
aureus) 		8 / 12 ALA A  69
SER A  70
SER A 130
ASN A 132
ASN A 170
LYS A 234
GLY A 236
ARG A 244
 None
 0.51A 4n9kB-1alqA:
24.3		 4n9kB-1alqA:
33.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4PM5_A_CE3A301_1
(BETA-LACTAMASE
CTX-M-14)		 1alq CP254 BETA-LACTAMASE
(Staphylococcus
aureus) 		6 / 12 TYR A 105
SER A 130
ASN A 132
ASN A 170
LYS A 234
GLY A 236
 None
 0.81A 4pm5A-1alqA:
28.0		 4pm5A-1alqA:
30.41
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4PM7_A_CE3A301_1
(BETA-LACTAMASE
CTX-M-14)		 1alq CP254 BETA-LACTAMASE
(Staphylococcus
aureus) 		7 / 12 LYS A  73
TYR A 105
SER A 130
ASN A 132
ASN A 170
LYS A 234
GLY A 236
 None
 0.79A 4pm7A-1alqA:
28.0		 4pm7A-1alqA:
30.60
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4PM9_A_CE3A301_1
(BETA-LACTAMASE
CTX-M-14)		 1alq CP254 BETA-LACTAMASE
(Staphylococcus
aureus) 		6 / 12 TYR A 105
SER A 130
ASN A 132
ASN A 170
LYS A 234
GLY A 236
 None
 0.81A 4pm9A-1alqA:
28.0		 4pm9A-1alqA:
31.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QZU_D_ACTD201_0
(RETINOL-BINDING
PROTEIN 2)		 1alq CP254 BETA-LACTAMASE
(Staphylococcus
aureus) 		3 / 3 ASP A 268
HIS A  43
LYS A 267
 None
 0.89A 4qzuD-1alqA:
undetectable		 4qzuD-1alqA:
18.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5GHY_A_CEDA301_1
(BETA-LACTAMASE)		 1alq CP254 BETA-LACTAMASE
(Staphylococcus
aureus) 		8 / 12 ALA A  69
SER A  70
SER A 130
ASN A 132
ASN A 170
LYS A 234
GLY A 236
ARG A 244
 None
 0.54A 5ghyA-1alqA:
29.9		 5ghyA-1alqA:
33.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5GHY_A_CEDA301_1
(BETA-LACTAMASE)		 1alq CP254 BETA-LACTAMASE
(Staphylococcus
aureus) 		7 / 12 ALA A  69
SER A  70
TYR A 105
ASN A 132
ASN A 170
GLY A 236
ARG A 244
 None
 1.12A 5ghyA-1alqA:
29.9		 5ghyA-1alqA:
33.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5GHY_B_CEDB301_1
(BETA-LACTAMASE)		 1alq CP254 BETA-LACTAMASE
(Staphylococcus
aureus) 		8 / 12 ALA A  69
SER A  70
SER A 130
ASN A 132
ASN A 170
LYS A 234
GLY A 236
ARG A 244
 None
 0.52A 5ghyB-1alqA:
30.2		 5ghyB-1alqA:
33.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5GHY_B_CEDB301_1
(BETA-LACTAMASE)		 1alq CP254 BETA-LACTAMASE
(Staphylococcus
aureus) 		7 / 12 ALA A  69
SER A  70
TYR A 105
ASN A 132
ASN A 170
GLY A 236
ARG A 244
 None
 1.07A 5ghyB-1alqA:
30.2		 5ghyB-1alqA:
33.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5GHZ_A_CEDA301_1
(BETA-LACTAMASE)		 1alq CP254 BETA-LACTAMASE
(Staphylococcus
aureus) 		9 / 11 ALA A  69
SER A  70
TYR A 105
SER A 130
ASN A 132
ASN A 170
LYS A 234
GLY A 236
ARG A 244
 None
 0.50A 5ghzA-1alqA:
30.1		 5ghzA-1alqA:
33.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5GHZ_B_CEDB301_1
(BETA-LACTAMASE)		 1alq CP254 BETA-LACTAMASE
(Staphylococcus
aureus) 		9 / 10 ALA A  69
SER A  70
TYR A 105
SER A 130
ASN A 132
ASN A 170
LYS A 234
GLY A 236
ARG A 244
 None
 0.53A 5ghzB-1alqA:
24.3		 5ghzB-1alqA:
33.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5J7W_C_MTXC402_1
(THYMIDYLATE SYNTHASE)		 1alq CP254 BETA-LACTAMASE
(Staphylococcus
aureus) 		5 / 12 ILE A  75
GLY A 187
PHE A 186
ILE A 194
ALA A 195
 None
 0.83A 5j7wC-1alqA:
0.0		 5j7wC-1alqA:
20.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5J7W_D_MTXD402_1
(THYMIDYLATE SYNTHASE)		 1alq CP254 BETA-LACTAMASE
(Staphylococcus
aureus) 		5 / 12 ILE A  75
GLY A 187
PHE A 186
ILE A 194
ALA A 195
 None
 0.83A 5j7wD-1alqA:
0.0		 5j7wD-1alqA:
20.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MUR_E_PFLE406_1
(PROTON-GATED ION
CHANNEL)		 1alq CP254 BETA-LACTAMASE
(Staphylococcus
aureus) 		5 / 10 PRO A 162
ILE A  75
ILE A 139
ILE A 142
ILE A 138
 None
 1.05A 5murE-1alqA:
0.3		 5murE-1alqA:
13.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UIG_A_EDTA501_0
(ADENOSINE RECEPTOR
A2A,SOLUBLE
CYTOCHROME
B562,ADENOSINE
RECEPTOR A2A)		 1alq CP254 BETA-LACTAMASE
(Staphylococcus
aureus) 		4 / 6 ASN A 136
THR A 133
ILE A 167
GLU A 168
 None
 1.34A 5uigA-1alqA:
undetectable		 5uigA-1alqA:
21.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B68_D_9F2D400_1
(BETA-LACTAMASE)		 1alq CP254 BETA-LACTAMASE
(Staphylococcus
aureus) 		5 / 12 SER A  70
SER A 130
ASN A 170
LYS A 234
GLY A 236
 None
 0.42A 6b68D-1alqA:
27.8		 6b68D-1alqA:
15.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6C_A_9F2A301_1
(BETA-LACTAMASE)		 1alq CP254 BETA-LACTAMASE
(Staphylococcus
aureus) 		5 / 12 SER A  70
SER A 130
ASN A 170
LYS A 234
GLY A 236
 None
 0.43A 6b6cA-1alqA:
27.4		 6b6cA-1alqA:
15.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6F_A_9F2A301_1
(BETA-LACTAMASE)		 1alq CP254 BETA-LACTAMASE
(Staphylococcus
aureus) 		5 / 12 SER A  70
SER A 130
ASN A 170
LYS A 234
GLY A 236
 None
 0.52A 6b6fA-1alqA:
27.3		 6b6fA-1alqA:
15.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6C79_A_CE3A301_1
(BETA-LACTAMASE
TOHO-1)		 1alq CP254 BETA-LACTAMASE
(Staphylococcus
aureus) 		6 / 12 TYR A 105
SER A 130
ASN A 132
ASN A 170
LYS A 234
GLY A 236
 None
 0.61A 6c79A-1alqA:
28.1		 6c79A-1alqA:
21.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6QYA_B_FOZB401_0
(THYMIDYLATE SYNTHASE)		 1alq CP254 BETA-LACTAMASE
(Staphylococcus
aureus) 		5 / 12 ILE A  75
GLY A 187
PHE A 186
ILE A 194
ALA A 195
 None
 0.89A 6qyaB-1alqA:
0.0		 6qyaB-1alqA:
20.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6QYA_D_FOZD401_0
(THYMIDYLATE SYNTHASE)		 1alq CP254 BETA-LACTAMASE
(Staphylococcus
aureus) 		5 / 12 ILE A  75
GLY A 187
PHE A 186
ILE A 194
ALA A 195
 None
 0.87A 6qyaD-1alqA:
0.0		 6qyaD-1alqA:
20.42