SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1am5'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AXW_B_MTXB733_1
(THYMIDYLATE SYNTHASE)		 1am5 PEPSIN
(Gadus
morhua) 		5 / 11 ASP A 303
LEU A 306
GLY A 302
PHE A 301
TYR A  14
 None
 1.30A 1axwB-1am5A:
undetectable		 1axwB-1am5A:
21.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AXW_B_MTXB733_1
(THYMIDYLATE SYNTHASE)		 1am5 PEPSIN
(Gadus
morhua) 		5 / 11 ASP A 303
LEU A 306
GLY A 302
PHE A 305
TYR A  14
 None
 1.49A 1axwB-1am5A:
undetectable		 1axwB-1am5A:
21.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HVY_A_D16A414_1
(THYMIDYLATE SYNTHASE)		 1am5 PEPSIN
(Gadus
morhua) 		5 / 12 ASP A 303
LEU A 306
GLY A 302
PHE A 301
TYR A  14
 None
 1.16A 1hvyA-1am5A:
0.0		 1hvyA-1am5A:
20.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HVY_B_D16B415_1
(THYMIDYLATE SYNTHASE)		 1am5 PEPSIN
(Gadus
morhua) 		5 / 12 ASP A 303
LEU A 306
GLY A 302
PHE A 301
TYR A  14
 None
 1.17A 1hvyB-1am5A:
0.0		 1hvyB-1am5A:
20.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HVY_C_D16C416_1
(THYMIDYLATE SYNTHASE)		 1am5 PEPSIN
(Gadus
morhua) 		5 / 11 ASP A 303
LEU A 306
GLY A 302
PHE A 301
TYR A  14
 None
 1.15A 1hvyC-1am5A:
0.0		 1hvyC-1am5A:
20.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I00_A_D16A315_1
(THYMIDYLATE SYNTHASE)		 1am5 PEPSIN
(Gadus
morhua) 		5 / 9 ASP A 303
LEU A 306
GLY A 302
PHE A 301
TYR A  14
 None
 1.23A 1i00A-1am5A:
0.0		 1i00A-1am5A:
21.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I00_B_D16B409_1
(THYMIDYLATE SYNTHASE)		 1am5 PEPSIN
(Gadus
morhua) 		5 / 9 ASP A 303
LEU A 306
GLY A 302
PHE A 301
TYR A  14
 None
 1.22A 1i00B-1am5A:
0.0		 1i00B-1am5A:
21.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JU6_A_LYAA317_1
(THYMIDYLATE SYNTHASE)		 1am5 PEPSIN
(Gadus
morhua) 		5 / 11 ASP A 303
LEU A 306
GLY A 302
PHE A 301
TYR A  14
 None
 1.28A 1ju6A-1am5A:
0.0		 1ju6A-1am5A:
21.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JU6_C_LYAC315_1
(THYMIDYLATE SYNTHASE)		 1am5 PEPSIN
(Gadus
morhua) 		5 / 10 ASP A 303
LEU A 306
GLY A 302
PHE A 301
TYR A  14
 None
 1.27A 1ju6C-1am5A:
0.0		 1ju6C-1am5A:
21.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RTS_A_D16A309_1
(THYMIDYLATE SYNTHASE)		 1am5 PEPSIN
(Gadus
morhua) 		4 / 8 ASP A 303
GLY A 302
PHE A 301
TYR A  14
 None
 0.79A 1rtsA-1am5A:
0.0		 1rtsA-1am5A:
22.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RTS_B_D16B409_1
(THYMIDYLATE SYNTHASE)		 1am5 PEPSIN
(Gadus
morhua) 		4 / 7 ASP A 303
GLY A 302
PHE A 301
TYR A  14
 None
 0.77A 1rtsB-1am5A:
undetectable		 1rtsB-1am5A:
22.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1S9P_B_DESB459_2
(ESTROGEN-RELATED
RECEPTOR GAMMA)		 1am5 PEPSIN
(Gadus
morhua) 		3 / 3 LEU A 101
HIS A  44
ILE A  83
 None
 0.69A 1s9pB-1am5A:
undetectable		 1s9pB-1am5A:
18.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AVO_B_MK1B902_2
(POL POLYPROTEIN)		 1am5 PEPSIN
(Gadus
morhua) 		6 / 12 ASP A 215
GLY A 217
ASP A 303
VAL A 222
VAL A 291
ILE A 300
 None
 1.26A 2avoB-1am5A:
8.0		 2avoB-1am5A:
13.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AVV_A_MK1A901_3
(POL POLYPROTEIN)		 1am5 PEPSIN
(Gadus
morhua) 		6 / 12 ASP A 215
GLY A 217
ASP A 303
VAL A 222
VAL A 291
ILE A 300
 None
 1.25A 2avvB-1am5A:
7.6		 2avvB-1am5A:
13.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BPX_B_MK1B902_2
(HIV-1 PROTEASE)		 1am5 PEPSIN
(Gadus
morhua) 		6 / 12 ASP A 215
GLY A 217
ASP A 303
VAL A 222
VAL A 291
ILE A 300
 None
 1.26A 2bpxB-1am5A:
7.1		 2bpxB-1am5A:
13.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OTF_A_2TNA201_1
(PHOSPHOLIPASE A2
VRV-PL-VIIIA)		 1am5 PEPSIN
(Gadus
morhua) 		4 / 5 LEU A  73
ILE A 128
SER A  36
GLY A 122
 None
 1.00A 2otfA-1am5A:
undetectable		 2otfA-1am5A:
15.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q63_A_1UNA1001_1
(PROTEASE RETROPEPSIN)		 1am5 PEPSIN
(Gadus
morhua) 		6 / 12 ASP A 215
GLY A 217
ASP A 303
VAL A 222
VAL A 291
ILE A 300
 None
 1.23A 2q63A-1am5A:
7.9		 2q63A-1am5A:
16.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q64_B_1UNB1001_3
(PROTEASE RETROPEPSIN)		 1am5 PEPSIN
(Gadus
morhua) 		5 / 12 ASP A  32
GLY A  34
ASN A  37
GLY A  76
ILE A 120
 None
 0.77A 2q64B-1am5A:
7.8		 2q64B-1am5A:
15.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QAK_A_1UNA1001_1
(PROTEASE RETROPEPSIN)		 1am5 PEPSIN
(Gadus
morhua) 		5 / 12 ASP A  32
GLY A  34
ASN A  37
GLY A  76
ILE A 120
 None
 0.73A 2qakA-1am5A:
7.8		 2qakA-1am5A:
16.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2R5P_B_MK1B902_2
(PROTEASE)		 1am5 PEPSIN
(Gadus
morhua) 		6 / 12 ASP A 215
GLY A 217
ASP A 303
VAL A 222
VAL A 291
ILE A 300
 None
 1.19A 2r5pB-1am5A:
7.9		 2r5pB-1am5A:
13.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2TSR_A_D16A309_1
(THYMIDYLATE SYNTHASE)		 1am5 PEPSIN
(Gadus
morhua) 		5 / 7 ASP A 303
LEU A 306
GLY A 302
PHE A 301
TYR A  14
 None
 1.18A 2tsrA-1am5A:
0.0		 2tsrA-1am5A:
22.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2TSR_B_D16B409_1
(THYMIDYLATE SYNTHASE)		 1am5 PEPSIN
(Gadus
morhua) 		5 / 8 ASP A 303
LEU A 306
GLY A 302
PHE A 301
TYR A  14
 None
 1.15A 2tsrB-1am5A:
undetectable		 2tsrB-1am5A:
22.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2TSR_C_D16C509_1
(THYMIDYLATE SYNTHASE)		 1am5 PEPSIN
(Gadus
morhua) 		5 / 10 ASP A 303
LEU A 306
GLY A 302
PHE A 301
TYR A  14
 None
 1.13A 2tsrC-1am5A:
undetectable		 2tsrC-1am5A:
22.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2TSR_D_D16D609_1
(THYMIDYLATE SYNTHASE)		 1am5 PEPSIN
(Gadus
morhua) 		5 / 9 ASP A 303
LEU A 306
GLY A 302
PHE A 301
TYR A  14
 None
 1.20A 2tsrD-1am5A:
0.0		 2tsrD-1am5A:
22.19
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2V0Z_C_C41C1328_1
(RENIN)		 1am5 PEPSIN
(Gadus
morhua) 		6 / 12 ASP A  32
GLY A  34
SER A  35
ASP A 215
GLY A 217
SER A 219
 None
 0.58A 2v0zC-1am5A:
42.7		 2v0zC-1am5A:
37.57
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2V0Z_C_C41C1328_1
(RENIN)		 1am5 PEPSIN
(Gadus
morhua) 		6 / 12 ASP A  32
GLY A  34
SER A  35
PHE A 117
ASP A 215
GLY A 217
 None
 0.65A 2v0zC-1am5A:
42.7		 2v0zC-1am5A:
37.57
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2V0Z_C_C41C1328_1
(RENIN)		 1am5 PEPSIN
(Gadus
morhua) 		5 / 12 ASP A 215
GLY A 217
ASP A  32
GLY A  34
SER A  36
 None
 0.84A 2v0zC-1am5A:
42.7		 2v0zC-1am5A:
37.57
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2V0Z_O_C41O1327_1
(RENIN)		 1am5 PEPSIN
(Gadus
morhua) 		6 / 12 ASP A  32
GLY A  34
ALA A 115
PHE A 117
ASP A 215
GLY A 217
 None
 0.62A 2v0zO-1am5A:
43.2		 2v0zO-1am5A:
37.57
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2V0Z_O_C41O1327_1
(RENIN)		 1am5 PEPSIN
(Gadus
morhua) 		5 / 12 ASP A  32
GLY A  34
ALA A 115
PHE A 117
ILE A 300
 None
 0.81A 2v0zO-1am5A:
43.2		 2v0zO-1am5A:
37.57
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2V0Z_O_C41O1327_1
(RENIN)		 1am5 PEPSIN
(Gadus
morhua) 		5 / 12 ASP A  32
GLY A  34
ASP A 215
GLY A 217
SER A 219
 None
 0.55A 2v0zO-1am5A:
43.2		 2v0zO-1am5A:
37.57
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2V0Z_O_C41O1327_1
(RENIN)		 1am5 PEPSIN
(Gadus
morhua) 		5 / 12 ASP A 215
GLY A 217
ASP A  32
GLY A  34
SER A  36
 None
 0.84A 2v0zO-1am5A:
43.2		 2v0zO-1am5A:
37.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y7K_A_SALA1302_1
(LYSR-TYPE REGULATORY
PROTEIN)		 1am5 PEPSIN
(Gadus
morhua) 		5 / 11 GLY A  85
GLY A  68
HIS A  44
PRO A  58
ILE A  83
 None
 1.41A 2y7kA-1am5A:
0.0		 2y7kA-1am5A:
21.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y7K_C_SALC1302_1
(LYSR-TYPE REGULATORY
PROTEIN)		 1am5 PEPSIN
(Gadus
morhua) 		5 / 12 GLY A  85
GLY A  68
HIS A  44
PRO A  58
ILE A  83
 None
 1.22A 2y7kC-1am5A:
undetectable		 2y7kC-1am5A:
21.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y7K_D_SALD1300_1
(LYSR-TYPE REGULATORY
PROTEIN)		 1am5 PEPSIN
(Gadus
morhua) 		5 / 12 GLY A  85
GLY A  68
HIS A  44
PRO A  58
ILE A  83
 None
 1.22A 2y7kD-1am5A:
0.0		 2y7kD-1am5A:
21.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y7W_B_SALB1300_1
(LYSR-TYPE REGULATORY
PROTEIN)		 1am5 PEPSIN
(Gadus
morhua) 		5 / 10 GLY A  85
GLY A  68
HIS A  44
PRO A  58
ILE A  83
 None
 1.17A 2y7wB-1am5A:
0.0		 2y7wB-1am5A:
20.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YGN_A_ACTA1181_0
(WNT INHIBITORY
FACTOR 1)		 1am5 PEPSIN
(Gadus
morhua) 		3 / 3 TYR A 310
VAL A 170
THR A 311
 None
 0.83A 2ygnA-1am5A:
undetectable		 2ygnA-1am5A:
18.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Z54_A_AB1A200_2
(HIV-1 PROTEASE)		 1am5 PEPSIN
(Gadus
morhua) 		6 / 12 ASP A 215
GLY A 217
ASP A 303
VAL A 222
VAL A 291
ILE A 300
 None
 1.21A 2z54B-1am5A:
7.8		 2z54B-1am5A:
13.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC8_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		 1am5 PEPSIN
(Gadus
morhua) 		3 / 3 SER A 251
GLY A 247
GLY A 236
 None
 0.55A 3bogA-1am5A:
0.0
3bogC-1am5A:
0.0		 3bogA-1am5A:
undetectable
3bogC-1am5A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K13_C_THHC643_0
(5-METHYLTETRAHYDROFO
LATE-HOMOCYSTEINE
METHYLTRANSFERASE)		 1am5 PEPSIN
(Gadus
morhua) 		5 / 12 GLU A 107
GLY A 119
GLY A  82
SER A 104
PHE A  56
 None
 1.25A 3k13C-1am5A:
undetectable		 3k13C-1am5A:
24.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KVV_B_URFB254_1
(URIDINE
PHOSPHORYLASE)		 1am5 PEPSIN
(Gadus
morhua) 		4 / 6 GLY A 119
MET A  80
ILE A  30
VAL A  29
 None
 1.16A 3kvvB-1am5A:
undetectable		 3kvvB-1am5A:
20.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LZU_A_017A200_2
(HIV-1 PROTEASE)		 1am5 PEPSIN
(Gadus
morhua) 		6 / 12 ASP A 215
GLY A 217
ASP A 303
VAL A 222
VAL A 291
ILE A 300
 None
 1.28A 3lzuB-1am5A:
7.5		 3lzuB-1am5A:
17.20
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3PRS_A_RITA1001_2
(ENDOTHIAPEPSIN)		 1am5 PEPSIN
(Gadus
morhua) 		5 / 12 ASP A  32
GLY A  34
ASP A 215
THR A 218
ILE A 300
 None
 0.42A 3prsA-1am5A:
37.5		 3prsA-1am5A:
30.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3Q70_A_RITA2001_1
(CANDIDAPEPSIN-2)		 1am5 PEPSIN
(Gadus
morhua) 		6 / 12 ILE A  30
ASP A  32
GLY A  34
ASP A 215
THR A 218
ILE A 300
 None
 0.37A 3q70A-1am5A:
10.3		 3q70A-1am5A:
29.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3Q70_A_RITA2001_1
(CANDIDAPEPSIN-2)		 1am5 PEPSIN
(Gadus
morhua) 		5 / 12 ILE A  30
ASP A  32
GLY A  34
GLY A  76
ASP A 215
 None
 0.47A 3q70A-1am5A:
10.3		 3q70A-1am5A:
29.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3Q70_A_RITA2001_1
(CANDIDAPEPSIN-2)		 1am5 PEPSIN
(Gadus
morhua) 		6 / 12 ILE A 213
ASP A 215
GLY A 217
GLU A  13
ASP A  32
ILE A 120
 None
 0.80A 3q70A-1am5A:
10.3		 3q70A-1am5A:
29.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T7V_A_SAMA992_0
(METHYLORNITHINE
SYNTHASE PYLB)		 1am5 PEPSIN
(Gadus
morhua) 		5 / 12 THR A 218
GLY A  34
LEU A 194
VAL A 222
ALA A 223
 None
 1.14A 3t7vA-1am5A:
undetectable		 3t7vA-1am5A:
21.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TNE_A_RITA401_1
(SECRETED ASPARTIC
PROTEASE)		 1am5 PEPSIN
(Gadus
morhua) 		5 / 12 ILE A  30
ASP A  32
GLY A  34
ASP A 215
ILE A 300
 None
 0.39A 3tneA-1am5A:
34.7		 3tneA-1am5A:
27.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TNE_A_RITA401_1
(SECRETED ASPARTIC
PROTEASE)		 1am5 PEPSIN
(Gadus
morhua) 		5 / 12 ILE A  30
ASP A  32
GLY A  34
GLY A  76
ASP A 215
 None
 0.69A 3tneA-1am5A:
34.7		 3tneA-1am5A:
27.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TNE_A_RITA401_1
(SECRETED ASPARTIC
PROTEASE)		 1am5 PEPSIN
(Gadus
morhua) 		5 / 12 ILE A 213
ASP A 215
GLY A 217
ASP A  32
ILE A 120
 None
 0.68A 3tneA-1am5A:
34.7		 3tneA-1am5A:
27.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TNE_B_RITB401_1
(SECRETED ASPARTIC
PROTEASE)		 1am5 PEPSIN
(Gadus
morhua) 		5 / 12 ILE A  30
ASP A  32
GLY A  34
ASP A 215
ILE A 300
 None
 0.42A 3tneB-1am5A:
34.8		 3tneB-1am5A:
27.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TNE_B_RITB401_1
(SECRETED ASPARTIC
PROTEASE)		 1am5 PEPSIN
(Gadus
morhua) 		5 / 12 ILE A  30
ASP A  32
GLY A  34
GLY A  76
ASP A 215
 None
 0.67A 3tneB-1am5A:
34.8		 3tneB-1am5A:
27.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TNE_B_RITB401_1
(SECRETED ASPARTIC
PROTEASE)		 1am5 PEPSIN
(Gadus
morhua) 		5 / 12 ILE A 213
ASP A 215
GLY A 217
ASP A  32
ILE A 120
 None
 0.70A 3tneB-1am5A:
34.8		 3tneB-1am5A:
27.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TNE_B_RITB401_1
(SECRETED ASPARTIC
PROTEASE)		 1am5 PEPSIN
(Gadus
morhua) 		5 / 12 ILE A 213
ASP A 215
GLY A 217
GLY A  76
ASP A  32
 None
 0.81A 3tneB-1am5A:
34.8		 3tneB-1am5A:
27.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VW7_A_VPXA2001_1
(PROTEINASE-ACTIVATED
RECEPTOR 1, LYSOZYME)		 1am5 PEPSIN
(Gadus
morhua) 		5 / 12 LEU A 167
PHE A  31
LEU A 121
ALA A 129
ALA A 133
 None
 0.97A 3vw7A-1am5A:
0.0		 3vw7A-1am5A:
20.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ACB_B_DXCB1473_0
(TRANSLATION
ELONGATION FACTOR
SELB)		 1am5 PEPSIN
(Gadus
morhua) 		4 / 8 ASP A  87
ILE A  20
GLY A  21
VAL A  29
 None
 0.74A 4acbB-1am5A:
undetectable
4acbC-1am5A:
undetectable		 4acbB-1am5A:
20.68
4acbC-1am5A:
20.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EB4_A_D16A402_1
(THYMIDYLATE SYNTHASE)		 1am5 PEPSIN
(Gadus
morhua) 		5 / 12 ASP A 303
LEU A 306
GLY A 302
PHE A 301
TYR A  14
 None
 1.18A 4eb4A-1am5A:
undetectable		 4eb4A-1am5A:
22.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EB4_B_D16B402_1
(THYMIDYLATE SYNTHASE)		 1am5 PEPSIN
(Gadus
morhua) 		5 / 12 ASP A 303
LEU A 306
GLY A 302
PHE A 301
TYR A  14
 None
 1.18A 4eb4B-1am5A:
0.0		 4eb4B-1am5A:
22.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EB4_C_D16C402_1
(THYMIDYLATE SYNTHASE)		 1am5 PEPSIN
(Gadus
morhua) 		5 / 9 ASP A 303
LEU A 306
GLY A 302
PHE A 301
TYR A  14
 None
 1.19A 4eb4C-1am5A:
0.0		 4eb4C-1am5A:
22.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EB4_D_D16D402_1
(THYMIDYLATE SYNTHASE)		 1am5 PEPSIN
(Gadus
morhua) 		5 / 10 ASP A 303
LEU A 306
GLY A 302
PHE A 301
TYR A  14
 None
 1.22A 4eb4D-1am5A:
0.0		 4eb4D-1am5A:
22.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IQQ_A_D16A402_1
(THYMIDYLATE SYNTHASE)		 1am5 PEPSIN
(Gadus
morhua) 		5 / 7 ASP A 303
LEU A 306
GLY A 302
PHE A 301
TYR A  14
 None
 1.23A 4iqqA-1am5A:
0.0		 4iqqA-1am5A:
22.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IQQ_B_D16B402_1
(THYMIDYLATE SYNTHASE)		 1am5 PEPSIN
(Gadus
morhua) 		5 / 7 ASP A 303
LEU A 306
GLY A 302
PHE A 301
TYR A  14
 None
 1.25A 4iqqB-1am5A:
0.0		 4iqqB-1am5A:
22.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IQQ_C_D16C402_1
(THYMIDYLATE SYNTHASE)		 1am5 PEPSIN
(Gadus
morhua) 		5 / 7 ASP A 303
LEU A 306
GLY A 302
PHE A 301
TYR A  14
 None
 1.17A 4iqqC-1am5A:
0.0		 4iqqC-1am5A:
22.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IQQ_D_D16D402_1
(THYMIDYLATE SYNTHASE)		 1am5 PEPSIN
(Gadus
morhua) 		5 / 8 ASP A 303
LEU A 306
GLY A 302
PHE A 301
TYR A  14
 None
 1.22A 4iqqD-1am5A:
undetectable		 4iqqD-1am5A:
22.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JEC_B_478B401_1
(HIV-1 PROTEASE)		 1am5 PEPSIN
(Gadus
morhua) 		6 / 12 ASP A 215
GLY A 217
ASP A 303
VAL A 222
VAL A 291
ILE A 300
 None
 1.23A 4jecA-1am5A:
7.7		 4jecA-1am5A:
13.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K8C_A_ADNA401_2
(SUGAR KINASE)		 1am5 PEPSIN
(Gadus
morhua) 		3 / 3 SER A  35
TYR A  75
PRO A 135
 None
 0.83A 4k8cA-1am5A:
undetectable		 4k8cA-1am5A:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAH_A_ADNA401_2
(PROBABLE SUGAR
KINASE PROTEIN)		 1am5 PEPSIN
(Gadus
morhua) 		3 / 3 SER A  35
TYR A  75
PRO A 135
 None
 0.85A 4kahA-1am5A:
undetectable		 4kahA-1am5A:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAH_B_ADNB502_2
(PROBABLE SUGAR
KINASE PROTEIN)		 1am5 PEPSIN
(Gadus
morhua) 		3 / 3 SER A  35
TYR A  75
PRO A 135
 None
 0.85A 4kahB-1am5A:
undetectable		 4kahB-1am5A:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAN_A_ADNA401_2
(PROBABLE SUGAR
KINASE PROTEIN)		 1am5 PEPSIN
(Gadus
morhua) 		3 / 3 SER A  35
TYR A  75
PRO A 135
 None
 0.82A 4kanA-1am5A:
undetectable		 4kanA-1am5A:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAN_B_ADNB401_2
(PROBABLE SUGAR
KINASE PROTEIN)		 1am5 PEPSIN
(Gadus
morhua) 		3 / 3 SER A  35
TYR A  75
PRO A 135
 None
 0.83A 4kanB-1am5A:
undetectable		 4kanB-1am5A:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KBE_A_ADNA401_2
(PROBABLE SUGAR
KINASE PROTEIN)		 1am5 PEPSIN
(Gadus
morhua) 		3 / 3 SER A  35
TYR A  75
PRO A 135
 None
 0.85A 4kbeA-1am5A:
undetectable		 4kbeA-1am5A:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KBE_B_ADNB401_2
(PROBABLE SUGAR
KINASE PROTEIN)		 1am5 PEPSIN
(Gadus
morhua) 		3 / 3 SER A  35
TYR A  75
PRO A 135
 None
 0.85A 4kbeB-1am5A:
undetectable		 4kbeB-1am5A:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LBG_A_ADNA401_2
(PROBABLE SUGAR
KINASE PROTEIN)		 1am5 PEPSIN
(Gadus
morhua) 		3 / 3 SER A  35
TYR A  75
PRO A 135
 None
 0.85A 4lbgA-1am5A:
undetectable		 4lbgA-1am5A:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LBG_B_ADNB401_2
(PROBABLE SUGAR
KINASE PROTEIN)		 1am5 PEPSIN
(Gadus
morhua) 		3 / 3 SER A  35
TYR A  75
PRO A 135
 None
 0.84A 4lbgB-1am5A:
undetectable		 4lbgB-1am5A:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Q5M_A_ROCA1101_3
(PROTEASE)		 1am5 PEPSIN
(Gadus
morhua) 		3 / 3 ASP A 215
ASP A  32
ASN A  37
 None
 0.58A 4q5mA-1am5A:
9.3		 4q5mA-1am5A:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5H3A_A_D16A401_1
(ORF70)		 1am5 PEPSIN
(Gadus
morhua) 		4 / 7 ASP A 303
GLY A 302
PHE A 301
TYR A  14
 None
 0.76A 5h3aA-1am5A:
undetectable		 5h3aA-1am5A:
19.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5H3A_B_D16B401_1
(ORF70)		 1am5 PEPSIN
(Gadus
morhua) 		5 / 7 ASP A 303
LEU A 306
GLY A 302
PHE A 301
TYR A  14
 None
 1.22A 5h3aB-1am5A:
0.0		 5h3aB-1am5A:
19.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NOO_A_D16A402_1
(THYMIDYLATE SYNTHASE)		 1am5 PEPSIN
(Gadus
morhua) 		4 / 7 ASP A 303
GLY A 302
PHE A 301
TYR A  14
 None
 0.81A 5nooA-1am5A:
0.0		 5nooA-1am5A:
22.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NOO_B_D16B402_1
(THYMIDYLATE SYNTHASE)		 1am5 PEPSIN
(Gadus
morhua) 		4 / 7 ASP A 303
GLY A 302
PHE A 301
TYR A  14
 None
 0.80A 5nooB-1am5A:
undetectable		 5nooB-1am5A:
22.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NOO_C_D16C402_1
(THYMIDYLATE SYNTHASE)		 1am5 PEPSIN
(Gadus
morhua) 		5 / 6 ASP A 303
LEU A 306
GLY A 302
PHE A 301
TYR A  14
 None
 1.22A 5nooC-1am5A:
0.0		 5nooC-1am5A:
22.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NOO_D_D16D402_1
(THYMIDYLATE SYNTHASE)		 1am5 PEPSIN
(Gadus
morhua) 		5 / 8 ASP A 303
LEU A 306
GLY A 302
PHE A 301
TYR A  14
 None
 1.25A 5nooD-1am5A:
undetectable		 5nooD-1am5A:
22.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X5Q_B_D16B402_1
(THYMIDYLATE SYNTHASE)		 1am5 PEPSIN
(Gadus
morhua) 		5 / 12 ASP A 303
LEU A 306
GLY A 302
PHE A 301
TYR A  14
 None
 1.21A 5x5qB-1am5A:
0.0		 5x5qB-1am5A:
20.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X5Q_C_D16C402_1
(THYMIDYLATE SYNTHASE)		 1am5 PEPSIN
(Gadus
morhua) 		4 / 7 ASP A 303
GLY A 302
PHE A 301
TYR A  14
 None
 0.79A 5x5qC-1am5A:
0.0		 5x5qC-1am5A:
20.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X5Q_D_D16D402_1
(THYMIDYLATE SYNTHASE)		 1am5 PEPSIN
(Gadus
morhua) 		4 / 8 ASP A 303
GLY A 302
PHE A 301
TYR A  14
 None
 0.77A 5x5qD-1am5A:
0.0		 5x5qD-1am5A:
20.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X5Q_F_D16F402_1
(THYMIDYLATE SYNTHASE)		 1am5 PEPSIN
(Gadus
morhua) 		5 / 8 ASP A 303
LEU A 306
GLY A 302
PHE A 301
TYR A  14
 None
 1.21A 5x5qF-1am5A:
0.0		 5x5qF-1am5A:
20.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X66_C_MTXC402_1
(THYMIDYLATE SYNTHASE)		 1am5 PEPSIN
(Gadus
morhua) 		5 / 9 ASP A 303
LEU A 306
GLY A 302
PHE A 301
TYR A  14
 None
 1.32A 5x66C-1am5A:
0.0		 5x66C-1am5A:
20.86