SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1amo'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A8U_B_BEZB294_0
(CHLOROPEROXIDASE T)		 1amo NADPH-CYTOCHROME
P450 REDUCTASE
(Rattus
norvegicus) 		5 / 10 GLY A 542
PHE A 540
LEU A 579
THR A 560
LEU A 588
 None
 1.07A 1a8uB-1amoA:
3.2		 1a8uB-1amoA:
19.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1BU5_A_RBFA301_1
(PROTEIN (FLAVODOXIN))		 1amo NADPH-CYTOCHROME
P450 REDUCTASE
(Rattus
norvegicus) 		4 / 7 THR A  90
THR A 139
GLY A 174
TYR A 178
 FMN  A 751 (-3.5A)
FMN  A 751 (-3.3A)
FMN  A 751 (-3.2A)
FMN  A 751 ( 3.9A)
 0.71A 1bu5A-1amoA:
17.7		 1bu5A-1amoA:
14.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OE2_A_CUA502_0
(DISSIMILATORY
COPPER-CONTAINING
NITRITE REDUCTASE)		 1amo NADPH-CYTOCHROME
P450 REDUCTASE
(Rattus
norvegicus) 		3 / 3 GLU A 304
HIS A 302
HIS A 470
 None
 0.71A 1oe2A-1amoA:
undetectable		 1oe2A-1amoA:
19.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1R15_C_NCAC439_0
(ADP-RIBOSYL CYCLASE)		 1amo NADPH-CYTOCHROME
P450 REDUCTASE
(Rattus
norvegicus) 		3 / 3 TRP A 219
PHE A 223
TRP A 224
 None
 1.08A 1r15C-1amoA:
1.5		 1r15C-1amoA:
17.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1R15_F_NCAF469_0
(ADP-RIBOSYL CYCLASE)		 1amo NADPH-CYTOCHROME
P450 REDUCTASE
(Rattus
norvegicus) 		3 / 3 TRP A 219
PHE A 223
TRP A 224
 None
 1.09A 1r15F-1amoA:
1.4		 1r15F-1amoA:
17.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1R15_G_NCAG479_0
(ADP-RIBOSYL CYCLASE)		 1amo NADPH-CYTOCHROME
P450 REDUCTASE
(Rattus
norvegicus) 		3 / 3 TRP A 219
PHE A 223
TRP A 224
 None
 1.10A 1r15G-1amoA:
1.7		 1r15G-1amoA:
17.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1R15_H_NCAH489_0
(ADP-RIBOSYL CYCLASE)		 1amo NADPH-CYTOCHROME
P450 REDUCTASE
(Rattus
norvegicus) 		3 / 3 TRP A 219
PHE A 223
TRP A 224
 None
 1.08A 1r15H-1amoA:
3.6		 1r15H-1amoA:
17.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1S9Q_A_CHDA459_0
(ESTROGEN-RELATED
RECEPTOR GAMMA)		 1amo NADPH-CYTOCHROME
P450 REDUCTASE
(Rattus
norvegicus) 		4 / 6 LEU A 330
VAL A 331
ILE A 334
TYR A 478
 None
None
None
FAD  A 750 (-3.4A)
 0.69A 1s9qA-1amoA:
undetectable		 1s9qA-1amoA:
17.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BDM_A_TMIA502_1
(CYTOCHROME P450 2B4)		 1amo NADPH-CYTOCHROME
P450 REDUCTASE
(Rattus
norvegicus) 		5 / 12 LEU A 371
LEU A 330
ILE A 377
ILE A 427
LEU A 338
 None
 1.03A 2bdmA-1amoA:
0.0		 2bdmA-1amoA:
22.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BR4_A_SAMA301_0
(CEPHALOSPORIN
HYDROXYLASE CMCI)		 1amo NADPH-CYTOCHROME
P450 REDUCTASE
(Rattus
norvegicus) 		5 / 12 LEU A 562
GLY A 536
CYH A 472
ALA A 538
ALA A 459
 None
None
None
FAD  A 750 (-3.7A)
None
 1.09A 2br4A-1amoA:
4.3		 2br4A-1amoA:
17.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BR4_D_SAMD301_0
(CEPHALOSPORIN
HYDROXYLASE CMCI)		 1amo NADPH-CYTOCHROME
P450 REDUCTASE
(Rattus
norvegicus) 		5 / 12 LEU A 562
GLY A 536
CYH A 472
ALA A 538
ALA A 459
 None
None
None
FAD  A 750 (-3.7A)
None
 1.18A 2br4D-1amoA:
4.2		 2br4D-1amoA:
17.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RK8_A_PPFA3969_1
(PHOSPHOENOLPYRUVATE
CARBOXYKINASE,
CYTOSOLIC [GTP])		 1amo NADPH-CYTOCHROME
P450 REDUCTASE
(Rattus
norvegicus) 		4 / 8 ARG A 519
HIS A 319
SER A 516
ASP A 675
 None
FAD  A 750 (-3.8A)
None
None
 1.39A 2rk8A-1amoA:
undetectable		 2rk8A-1amoA:
20.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_A_P1ZA1353_1
(PROSTAGLANDIN
REDUCTASE 2)		 1amo NADPH-CYTOCHROME
P450 REDUCTASE
(Rattus
norvegicus) 		5 / 9 PHE A 223
GLU A 221
GLY A 204
PHE A 216
GLU A 214
 None
 1.08A 2w98A-1amoA:
4.0		 2w98A-1amoA:
19.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_C_SVRC507_2
(PHOSPHOLIPASE A2)		 1amo NADPH-CYTOCHROME
P450 REDUCTASE
(Rattus
norvegicus) 		4 / 6 VAL A 513
VAL A 320
PHE A 276
ARG A 454
 None
None
None
FAD  A 750 (-3.8A)
 1.19A 3bjwF-1amoA:
0.0		 3bjwF-1amoA:
11.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K4V_B_ROCB201_1
(HIV-1 PROTEASE)		 1amo NADPH-CYTOCHROME
P450 REDUCTASE
(Rattus
norvegicus) 		6 / 12 LEU A 292
GLY A 536
ALA A 538
ILE A 458
GLY A 542
ILE A 544
 None
None
FAD  A 750 (-3.7A)
None
None
None
 1.34A 3k4vA-1amoA:
undetectable		 3k4vA-1amoA:
9.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K4V_B_ROCB201_3
(HIV-1 PROTEASE)		 1amo NADPH-CYTOCHROME
P450 REDUCTASE
(Rattus
norvegicus) 		6 / 12 LEU A 292
GLY A 536
ALA A 538
ILE A 458
GLY A 542
ILE A 544
 None
None
FAD  A 750 (-3.7A)
None
None
None
 1.34A 3k4vB-1amoA:
undetectable		 3k4vB-1amoA:
9.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K4V_B_ROCB201_4
(HIV-1 PROTEASE)		 1amo NADPH-CYTOCHROME
P450 REDUCTASE
(Rattus
norvegicus) 		4 / 4 ARG A 454
ASP A 209
GLY A 174
THR A  90
 FAD  A 750 (-3.8A)
None
FMN  A 751 (-3.2A)
FMN  A 751 (-3.5A)
 1.22A 3k4vB-1amoA:
undetectable		 3k4vB-1amoA:
9.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MDV_B_CL6B506_1
(CHOLESTEROL
24-HYDROXYLASE)		 1amo NADPH-CYTOCHROME
P450 REDUCTASE
(Rattus
norvegicus) 		5 / 12 LEU A 292
LEU A 579
THR A 535
ILE A 537
ALA A 538
 None
None
NAP  A 752 (-3.5A)
None
FAD  A 750 (-3.7A)
 0.76A 3mdvB-1amoA:
0.0		 3mdvB-1amoA:
22.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MTE_A_SAMA220_0
(16S RRNA METHYLASE)		 1amo NADPH-CYTOCHROME
P450 REDUCTASE
(Rattus
norvegicus) 		5 / 12 GLY A 534
GLY A 565
VAL A 531
ALA A 538
SER A 596
 NAP  A 752 (-3.3A)
NAP  A 752 ( 4.9A)
None
FAD  A 750 (-3.7A)
NAP  A 752 (-2.7A)
 1.21A 3mteA-1amoA:
2.3		 3mteA-1amoA:
16.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDT_A_ROCA101_1
(PROTEASE)		 1amo NADPH-CYTOCHROME
P450 REDUCTASE
(Rattus
norvegicus) 		6 / 12 LEU A 292
GLY A 536
ALA A 538
ILE A 458
GLY A 542
ILE A 544
 None
None
FAD  A 750 (-3.7A)
None
None
None
 1.36A 3ndtA-1amoA:
undetectable		 3ndtA-1amoA:
9.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QPS_A_CHDA211_0
(CMER)		 1amo NADPH-CYTOCHROME
P450 REDUCTASE
(Rattus
norvegicus) 		5 / 10 LEU A 562
ALA A 538
PHE A 540
GLY A 542
ILE A 544
 None
FAD  A 750 (-3.7A)
None
None
None
 1.03A 3qpsA-1amoA:
0.0		 3qpsA-1amoA:
15.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RUK_D_AERD601_1
(STEROID
17-ALPHA-HYDROXYLASE
/17,20 LYASE)		 1amo NADPH-CYTOCHROME
P450 REDUCTASE
(Rattus
norvegicus) 		5 / 11 ALA A 112
PHE A  83
ASN A  79
GLY A 109
THR A  76
 None
 0.96A 3rukD-1amoA:
undetectable		 3rukD-1amoA:
20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TKW_B_017B401_2
(PROTEASE)		 1amo NADPH-CYTOCHROME
P450 REDUCTASE
(Rattus
norvegicus) 		6 / 12 LEU A 292
GLY A 536
ALA A 538
ILE A 458
GLY A 542
ILE A 544
 None
None
FAD  A 750 (-3.7A)
None
None
None
 1.45A 3tkwB-1amoA:
undetectable		 3tkwB-1amoA:
10.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F4D_B_CHDB504_0
(FERROCHELATASE,
MITOCHONDRIAL)		 1amo NADPH-CYTOCHROME
P450 REDUCTASE
(Rattus
norvegicus) 		4 / 4 LEU A 437
PRO A 439
LEU A 431
ILE A 430
 None
 0.98A 4f4dB-1amoA:
3.6		 4f4dB-1amoA:
19.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IG5_A_MMZA616_1
(LACTOPEROXIDASE)		 1amo NADPH-CYTOCHROME
P450 REDUCTASE
(Rattus
norvegicus) 		4 / 5 HIS A 443
ARG A 243
GLU A 388
LEU A 447
 None
 1.44A 4ig5A-1amoA:
0.1		 4ig5A-1amoA:
22.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IG5_B_MMZB617_1
(LACTOPEROXIDASE)		 1amo NADPH-CYTOCHROME
P450 REDUCTASE
(Rattus
norvegicus) 		4 / 5 HIS A 443
ARG A 243
GLU A 388
LEU A 447
 None
 1.41A 4ig5B-1amoA:
undetectable		 4ig5B-1amoA:
22.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N48_B_SAMB601_1
(CAP-SPECIFIC MRNA
(NUCLEOSIDE-2'-O-)-M
ETHYLTRANSFERASE 1)		 1amo NADPH-CYTOCHROME
P450 REDUCTASE
(Rattus
norvegicus) 		4 / 5 ASN A 182
GLY A 174
ASP A 101
ASP A 215
 FMN  A 751 (-4.9A)
FMN  A 751 (-3.2A)
None
None
 1.09A 4n48B-1amoA:
3.1		 4n48B-1amoA:
20.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N49_A_SAMA601_1
(CAP-SPECIFIC MRNA
(NUCLEOSIDE-2'-O-)-M
ETHYLTRANSFERASE 1)		 1amo NADPH-CYTOCHROME
P450 REDUCTASE
(Rattus
norvegicus) 		4 / 4 ASN A 182
GLY A 174
ASP A 101
ASP A 215
 FMN  A 751 (-4.9A)
FMN  A 751 (-3.2A)
None
None
 1.12A 4n49A-1amoA:
2.8		 4n49A-1amoA:
20.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NKX_B_STRB601_1
(STEROID
17-ALPHA-HYDROXYLASE
/17,20 LYASE)		 1amo NADPH-CYTOCHROME
P450 REDUCTASE
(Rattus
norvegicus) 		5 / 12 ALA A 112
ASN A  79
ILE A 128
GLY A 109
THR A  76
 None
 0.92A 4nkxB-1amoA:
0.0		 4nkxB-1amoA:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OBW_C_SAMC601_0
(2-METHOXY-6-POLYPREN
YL-1,4-BENZOQUINOL
METHYLASE,
MITOCHONDRIAL)		 1amo NADPH-CYTOCHROME
P450 REDUCTASE
(Rattus
norvegicus) 		5 / 12 ASN A 211
GLY A 174
ASP A 209
GLY A  85
ARG A 382
 None
FMN  A 751 (-3.2A)
None
None
None
 1.29A 4obwC-1amoA:
3.4		 4obwC-1amoA:
18.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P6X_I_HCYI900_2
(GLUCOCORTICOID
RECEPTOR)		 1amo NADPH-CYTOCHROME
P450 REDUCTASE
(Rattus
norvegicus) 		3 / 3 MET A 301
MET A 541
TYR A 456
 None
None
FAD  A 750 (-4.3A)
 1.34A 4p6xI-1amoA:
0.0		 4p6xI-1amoA:
17.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5D4U_C_SAMC301_0
(UNCHARACTERIZED
PROTEIN MJ0489)		 1amo NADPH-CYTOCHROME
P450 REDUCTASE
(Rattus
norvegicus) 		5 / 12 GLY A 565
TYR A 604
LEU A 562
GLY A 536
ILE A 537
 NAP  A 752 ( 4.9A)
NAP  A 752 (-3.7A)
None
None
None
 0.97A 5d4uC-1amoA:
undetectable		 5d4uC-1amoA:
19.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5D4U_D_SAMD301_0
(UNCHARACTERIZED
PROTEIN MJ0489)		 1amo NADPH-CYTOCHROME
P450 REDUCTASE
(Rattus
norvegicus) 		5 / 12 GLY A 565
TYR A 604
LEU A 562
GLY A 536
ILE A 537
 NAP  A 752 ( 4.9A)
NAP  A 752 (-3.7A)
None
None
None
 0.95A 5d4uD-1amoA:
undetectable		 5d4uD-1amoA:
19.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FF1_A_MMZA601_1
(LACTOPEROXIDASE)		 1amo NADPH-CYTOCHROME
P450 REDUCTASE
(Rattus
norvegicus) 		4 / 5 HIS A 443
ARG A 243
GLU A 388
LEU A 447
 None
 1.44A 5ff1A-1amoA:
0.0		 5ff1A-1amoA:
22.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FF1_A_MMZA602_1
(LACTOPEROXIDASE)		 1amo NADPH-CYTOCHROME
P450 REDUCTASE
(Rattus
norvegicus) 		4 / 5 HIS A 443
ARG A 243
GLU A 388
LEU A 447
 None
 1.44A 5ff1A-1amoA:
0.0		 5ff1A-1amoA:
22.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FF1_B_MMZB601_1
(LACTOPEROXIDASE)		 1amo NADPH-CYTOCHROME
P450 REDUCTASE
(Rattus
norvegicus) 		4 / 5 HIS A 443
ARG A 243
GLU A 388
LEU A 447
 None
 1.45A 5ff1B-1amoA:
0.0		 5ff1B-1amoA:
22.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FF1_B_MMZB613_1
(LACTOPEROXIDASE)		 1amo NADPH-CYTOCHROME
P450 REDUCTASE
(Rattus
norvegicus) 		4 / 5 HIS A 443
ARG A 243
GLU A 388
LEU A 447
 None
 1.45A 5ff1B-1amoA:
0.0		 5ff1B-1amoA:
22.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FHR_B_SAMB303_1
(CATECHOL
O-METHYLTRANSFERASE)		 1amo NADPH-CYTOCHROME
P450 REDUCTASE
(Rattus
norvegicus) 		4 / 5 SER A 310
SER A 460
GLN A 545
ASP A 306
 None
 1.42A 5fhrB-1amoA:
3.8		 5fhrB-1amoA:
17.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HHJ_A_GLYA403_0
(RETRON-TYPE REVERSE
TRANSCRIPTASE)		 1amo NADPH-CYTOCHROME
P450 REDUCTASE
(Rattus
norvegicus) 		4 / 4 LEU A 428
LEU A 338
GLY A 335
GLU A 336
 None
 1.13A 5hhjA-1amoA:
0.0		 5hhjA-1amoA:
18.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NU7_A_RTLA201_0
(RETINOL-BINDING
PROTEIN 4)		 1amo NADPH-CYTOCHROME
P450 REDUCTASE
(Rattus
norvegicus) 		4 / 8 LEU A 609
ALA A 625
VAL A 605
TYR A 672
 None
 0.93A 5nu7A-1amoA:
0.0		 5nu7A-1amoA:
16.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGU_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 1amo NADPH-CYTOCHROME
P450 REDUCTASE
(Rattus
norvegicus) 		3 / 3 VAL A 629
VAL A 531
GLN A 606
 None
None
NAP  A 752 (-2.9A)
 0.66A 5qguA-1amoA:
0.0		 5qguA-1amoA:
14.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGV_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 1amo NADPH-CYTOCHROME
P450 REDUCTASE
(Rattus
norvegicus) 		3 / 3 VAL A 629
VAL A 531
GLN A 606
 None
None
NAP  A 752 (-2.9A)
 0.64A 5qgvA-1amoA:
0.0		 5qgvA-1amoA:
14.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGW_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 1amo NADPH-CYTOCHROME
P450 REDUCTASE
(Rattus
norvegicus) 		3 / 3 VAL A 629
VAL A 531
GLN A 606
 None
None
NAP  A 752 (-2.9A)
 0.62A 5qgwA-1amoA:
0.0		 5qgwA-1amoA:
14.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGX_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 1amo NADPH-CYTOCHROME
P450 REDUCTASE
(Rattus
norvegicus) 		3 / 3 VAL A 629
VAL A 531
GLN A 606
 None
None
NAP  A 752 (-2.9A)
 0.64A 5qgxA-1amoA:
0.0		 5qgxA-1amoA:
14.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGY_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 1amo NADPH-CYTOCHROME
P450 REDUCTASE
(Rattus
norvegicus) 		3 / 3 VAL A 629
VAL A 531
GLN A 606
 None
None
NAP  A 752 (-2.9A)
 0.64A 5qgyA-1amoA:
0.0		 5qgyA-1amoA:
14.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGZ_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 1amo NADPH-CYTOCHROME
P450 REDUCTASE
(Rattus
norvegicus) 		3 / 3 VAL A 629
VAL A 531
GLN A 606
 None
None
NAP  A 752 (-2.9A)
 0.62A 5qgzA-1amoA:
0.0		 5qgzA-1amoA:
14.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QH0_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 1amo NADPH-CYTOCHROME
P450 REDUCTASE
(Rattus
norvegicus) 		3 / 3 VAL A 629
VAL A 531
GLN A 606
 None
None
NAP  A 752 (-2.9A)
 0.63A 5qh0A-1amoA:
0.0		 5qh0A-1amoA:
14.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QH1_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 1amo NADPH-CYTOCHROME
P450 REDUCTASE
(Rattus
norvegicus) 		3 / 3 VAL A 629
VAL A 531
GLN A 606
 None
None
NAP  A 752 (-2.9A)
 0.64A 5qh1A-1amoA:
0.0		 5qh1A-1amoA:
14.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QH2_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 1amo NADPH-CYTOCHROME
P450 REDUCTASE
(Rattus
norvegicus) 		3 / 3 VAL A 629
VAL A 531
GLN A 606
 None
None
NAP  A 752 (-2.9A)
 0.62A 5qh2A-1amoA:
0.0		 5qh2A-1amoA:
14.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QH3_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 1amo NADPH-CYTOCHROME
P450 REDUCTASE
(Rattus
norvegicus) 		3 / 3 VAL A 629
VAL A 531
GLN A 606
 None
None
NAP  A 752 (-2.9A)
 0.63A 5qh3A-1amoA:
0.0		 5qh3A-1amoA:
14.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QH4_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 1amo NADPH-CYTOCHROME
P450 REDUCTASE
(Rattus
norvegicus) 		3 / 3 VAL A 629
VAL A 531
GLN A 606
 None
None
NAP  A 752 (-2.9A)
 0.67A 5qh4A-1amoA:
0.0		 5qh4A-1amoA:
14.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QH6_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 1amo NADPH-CYTOCHROME
P450 REDUCTASE
(Rattus
norvegicus) 		3 / 3 VAL A 629
VAL A 531
GLN A 606
 None
None
NAP  A 752 (-2.9A)
 0.63A 5qh6A-1amoA:
0.0		 5qh6A-1amoA:
14.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QH7_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 1amo NADPH-CYTOCHROME
P450 REDUCTASE
(Rattus
norvegicus) 		3 / 3 VAL A 629
VAL A 531
GLN A 606
 None
None
NAP  A 752 (-2.9A)
 0.66A 5qh7A-1amoA:
0.0		 5qh7A-1amoA:
14.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QH9_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 1amo NADPH-CYTOCHROME
P450 REDUCTASE
(Rattus
norvegicus) 		3 / 3 VAL A 629
VAL A 531
GLN A 606
 None
None
NAP  A 752 (-2.9A)
 0.64A 5qh9A-1amoA:
0.0		 5qh9A-1amoA:
14.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QHA_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 1amo NADPH-CYTOCHROME
P450 REDUCTASE
(Rattus
norvegicus) 		3 / 3 VAL A 629
VAL A 531
GLN A 606
 None
None
NAP  A 752 (-2.9A)
 0.58A 5qhaA-1amoA:
0.0		 5qhaA-1amoA:
14.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QHC_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 1amo NADPH-CYTOCHROME
P450 REDUCTASE
(Rattus
norvegicus) 		3 / 3 VAL A 629
VAL A 531
GLN A 606
 None
None
NAP  A 752 (-2.9A)
 0.66A 5qhcA-1amoA:
0.0		 5qhcA-1amoA:
14.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QHE_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 1amo NADPH-CYTOCHROME
P450 REDUCTASE
(Rattus
norvegicus) 		3 / 3 VAL A 629
VAL A 531
GLN A 606
 None
None
NAP  A 752 (-2.9A)
 0.65A 5qheA-1amoA:
0.0		 5qheA-1amoA:
14.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QHF_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 1amo NADPH-CYTOCHROME
P450 REDUCTASE
(Rattus
norvegicus) 		3 / 3 VAL A 629
VAL A 531
GLN A 606
 None
None
NAP  A 752 (-2.9A)
 0.64A 5qhfA-1amoA:
0.0		 5qhfA-1amoA:
14.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QHG_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 1amo NADPH-CYTOCHROME
P450 REDUCTASE
(Rattus
norvegicus) 		3 / 3 VAL A 629
VAL A 531
GLN A 606
 None
None
NAP  A 752 (-2.9A)
 0.71A 5qhgA-1amoA:
0.0		 5qhgA-1amoA:
14.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QHH_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 1amo NADPH-CYTOCHROME
P450 REDUCTASE
(Rattus
norvegicus) 		3 / 3 VAL A 629
VAL A 531
GLN A 606
 None
None
NAP  A 752 (-2.9A)
 0.66A 5qhhA-1amoA:
0.0		 5qhhA-1amoA:
14.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TIW_A_OAQA302_0
(SULFOTRANSFERASE)		 1amo NADPH-CYTOCHROME
P450 REDUCTASE
(Rattus
norvegicus) 		5 / 12 PRO A 360
ILE A 441
ILE A 377
LEU A 338
LEU A 431
 None
 1.26A 5tiwA-1amoA:
2.0		 5tiwA-1amoA:
16.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TZO_B_7V7B201_2
(ENDO-1,4-BETA-XYLANA
SE A)		 1amo NADPH-CYTOCHROME
P450 REDUCTASE
(Rattus
norvegicus) 		3 / 3 ARG A 450
PRO A 362
TYR A 323
 None
 0.70A 5tzoB-1amoA:
undetectable		 5tzoB-1amoA:
15.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UXC_A_ZITA307_1
(PREDICTED
AMINOGLYCOSIDE
PHOSPHOTRANSFERASE)		 1amo NADPH-CYTOCHROME
P450 REDUCTASE
(Rattus
norvegicus) 		4 / 5 ASP A 585
GLU A 559
ARG A 547
THR A 589
 None
 1.45A 5uxcA-1amoA:
0.0		 5uxcA-1amoA:
20.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VW4_A_NCAA403_0
(FERREDOXIN--NADP
REDUCTASE)		 1amo NADPH-CYTOCHROME
P450 REDUCTASE
(Rattus
norvegicus) 		6 / 9 SER A 457
THR A 535
GLY A 536
ALA A 538
CYH A 630
GLY A 631
 FAD  A 750 (-3.8A)
NAP  A 752 (-3.5A)
None
FAD  A 750 (-3.7A)
None
None
 0.56A 5vw4A-1amoA:
29.7		 5vw4A-1amoA:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VW5_A_NCAA403_0
(FERREDOXIN--NADP
REDUCTASE)		 1amo NADPH-CYTOCHROME
P450 REDUCTASE
(Rattus
norvegicus) 		4 / 8 SER A 457
GLY A 536
CYH A 630
GLY A 631
 FAD  A 750 (-3.8A)
None
None
None
 0.47A 5vw5A-1amoA:
29.5		 5vw5A-1amoA:
20.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VW5_A_NCAA403_0
(FERREDOXIN--NADP
REDUCTASE)		 1amo NADPH-CYTOCHROME
P450 REDUCTASE
(Rattus
norvegicus) 		4 / 8 THR A 535
GLY A 536
CYH A 630
GLY A 631
 NAP  A 752 (-3.5A)
None
None
None
 0.35A 5vw5A-1amoA:
29.5		 5vw5A-1amoA:
20.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VW9_A_NCAA403_0
(FERREDOXIN--NADP
REDUCTASE)		 1amo NADPH-CYTOCHROME
P450 REDUCTASE
(Rattus
norvegicus) 		6 / 8 SER A 457
THR A 535
GLY A 536
ALA A 538
CYH A 630
GLY A 631
 FAD  A 750 (-3.8A)
NAP  A 752 (-3.5A)
None
FAD  A 750 (-3.7A)
None
None
 0.58A 5vw9A-1amoA:
29.8		 5vw9A-1amoA:
20.83