SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1amx'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W9S_B_TOPB1160_1
(DIHYDROFOLATE
REDUCTASE TYPE 1
FROM TN4003)		 1amx COLLAGEN ADHESIN
(Staphylococcus
aureus) 		5 / 11 ILE A 205
ALA A 297
LEU A 192
ILE A 194
ILE A 252
 None
 1.05A 2w9sB-1amxA:
undetectable		 2w9sB-1amxA:
24.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DDY_A_RBFA187_1
(LUMAZINE PROTEIN)		 1amx COLLAGEN ADHESIN
(Staphylococcus
aureus) 		5 / 12 SER A 276
ILE A 207
ASP A 209
ASN A 223
ILE A 224
 None
 1.23A 3ddyA-1amxA:
0.3		 3ddyA-1amxA:
23.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FQD_E_LVYE1438_1
(PROTEIN CEREBLON
CASEIN KINASE I
ISOFORM ALPHA)		 1amx COLLAGEN ADHESIN
(Staphylococcus
aureus) 		5 / 12 ASN A 273
HIS A 230
SER A 199
PHE A 173
GLY A 268
 None
 1.45A 5fqdE-1amxA:
0.0
5fqdF-1amxA:
0.0		 5fqdE-1amxA:
16.36
5fqdF-1amxA:
19.71