SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1amy'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DED_B_QPSB1501_1
(CYCLODEXTRIN
GLUCANOTRANSFERASE)		 1amy 1,4-ALPHA-D-GLUCAN
GLUCANOHYDROLASE
(Hordeum
vulgare) 		6 / 12 TYR A  51
ARG A 177
ASP A 179
GLU A 204
HIS A 288
ASP A 289
 None
 0.77A 1dedB-1amyA:
28.2		 1dedB-1amyA:
21.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EIZ_A_SAMA301_1
(FTSJ)		 1amy 1,4-ALPHA-D-GLUCAN
GLUCANOHYDROLASE
(Hordeum
vulgare) 		3 / 3 ASP A 396
ASP A 302
ASP A 360
 None
 0.66A 1eizA-1amyA:
undetectable		 1eizA-1amyA:
20.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EJ0_A_SAMA301_1
(FTSJ)		 1amy 1,4-ALPHA-D-GLUCAN
GLUCANOHYDROLASE
(Hordeum
vulgare) 		3 / 3 ASP A 396
ASP A 302
ASP A 360
 None
 0.68A 1ej0A-1amyA:
undetectable		 1ej0A-1amyA:
20.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1J96_A_TESA903_1
(3ALPHA-HYDROXYSTEROI
D DEHYDROGENASE TYPE
3)		 1amy 1,4-ALPHA-D-GLUCAN
GLUCANOHYDROLASE
(Hordeum
vulgare) 		4 / 6 TYR A  64
VAL A  89
ILE A  88
LEU A  70
 None
 1.32A 1j96A-1amyA:
9.1		 1j96A-1amyA:
19.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KXH_A_ACRA598_1
(ALPHA-AMYLASE)		 1amy 1,4-ALPHA-D-GLUCAN
GLUCANOHYDROLASE
(Hordeum
vulgare) 		5 / 12 TRP A   9
HIS A  92
GLY A 144
GLU A 204
ASP A 289
 None
None
CA  A 502 (-4.4A)
None
None
 1.02A 1kxhA-1amyA:
28.2		 1kxhA-1amyA:
23.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MX1_E_THAE5_2
(LIVER
CARBOXYLESTERASE I)		 1amy 1,4-ALPHA-D-GLUCAN
GLUCANOHYDROLASE
(Hordeum
vulgare) 		3 / 3 PHE A 173
LEU A  70
LEU A  59
 None
 0.62A 1mx1E-1amyA:
1.5		 1mx1E-1amyA:
21.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MXD_A_ACRA735_1
(ALPHA AMYLASE)		 1amy 1,4-ALPHA-D-GLUCAN
GLUCANOHYDROLASE
(Hordeum
vulgare) 		10 / 12 TRP A   9
TYR A  51
HIS A  92
ARG A 177
ASP A 179
LYS A 182
GLU A 204
TRP A 206
HIS A 288
ASP A 289
 None
 0.45A 1mxdA-1amyA:
41.1		 1mxdA-1amyA:
28.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MXD_A_ACRA735_1
(ALPHA AMYLASE)		 1amy 1,4-ALPHA-D-GLUCAN
GLUCANOHYDROLASE
(Hordeum
vulgare) 		8 / 12 TYR A  51
HIS A  92
PHE A 143
ARG A 177
ASP A 179
LYS A 182
GLU A 204
HIS A 288
 None
 0.70A 1mxdA-1amyA:
41.1		 1mxdA-1amyA:
28.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RS6_B_ACTB861_0
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 1amy 1,4-ALPHA-D-GLUCAN
GLUCANOHYDROLASE
(Hordeum
vulgare) 		4 / 5 GLY A   6
GLN A   5
TRP A  38
SER A  11
 None
 1.32A 1rs6B-1amyA:
0.0		 1rs6B-1amyA:
22.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1X70_B_715B801_2
(DIPEPTIDYL PEPTIDASE
IV)		 1amy 1,4-ALPHA-D-GLUCAN
GLUCANOHYDROLASE
(Hordeum
vulgare) 		3 / 3 PHE A 173
TYR A  19
TYR A  64
 None
 0.90A 1x70B-1amyA:
0.0		 1x70B-1amyA:
19.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZZQ_B_ACTB861_0
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 1amy 1,4-ALPHA-D-GLUCAN
GLUCANOHYDROLASE
(Hordeum
vulgare) 		4 / 5 GLY A   6
GLN A   5
TRP A  38
SER A  11
 None
 1.10A 1zzqB-1amyA:
0.0		 1zzqB-1amyA:
22.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZZU_A_ACTA860_0
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 1amy 1,4-ALPHA-D-GLUCAN
GLUCANOHYDROLASE
(Hordeum
vulgare) 		4 / 5 GLY A   6
GLN A   5
TRP A  38
SER A  11
 None
 1.15A 1zzuA-1amyA:
0.0		 1zzuA-1amyA:
22.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AVV_E_MK1E902_2
(POL POLYPROTEIN)		 1amy 1,4-ALPHA-D-GLUCAN
GLUCANOHYDROLASE
(Hordeum
vulgare) 		3 / 3 ASP A 174
ILE A  34
VAL A 282
 None
 0.68A 2avvD-1amyA:
undetectable		 2avvD-1amyA:
13.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2C49_A_ADNA1301_1
(SUGAR KINASE MJ0406)		 1amy 1,4-ALPHA-D-GLUCAN
GLUCANOHYDROLASE
(Hordeum
vulgare) 		5 / 12 ALA A 141
ASP A 138
GLY A 140
GLY A 183
ASP A 179
 None
CA  A 500 (-2.3A)
CA  A 500 ( 4.8A)
CA  A 500 (-3.6A)
None
 1.17A 2c49A-1amyA:
undetectable		 2c49A-1amyA:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FXD_A_DR7A102_1
(POL PROTEIN)		 1amy 1,4-ALPHA-D-GLUCAN
GLUCANOHYDROLASE
(Hordeum
vulgare) 		5 / 11 ILE A  74
LEU A  77
ALA A  30
ILE A 320
VAL A  82
 None
 0.89A 2fxdA-1amyA:
undetectable		 2fxdA-1amyA:
14.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JN3_A_JN3A130_1
(FATTY ACID-BINDING
PROTEIN, LIVER)		 1amy 1,4-ALPHA-D-GLUCAN
GLUCANOHYDROLASE
(Hordeum
vulgare) 		5 / 12 LEU A  70
LEU A  77
ALA A  84
ILE A  85
LEU A  59
 None
 1.15A 2jn3A-1amyA:
undetectable		 2jn3A-1amyA:
13.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2QPU_B_QPSB3000_1
(ALPHA-AMYLASE TYPE A
ISOZYME)		 1amy 1,4-ALPHA-D-GLUCAN
GLUCANOHYDROLASE
(Hordeum
vulgare) 		6 / 9 LYS A 373
VAL A 380
HIS A 393
ASP A 396
ALA A 398
TRP A 400
 None
 0.50A 2qpuB-1amyA:
17.1		 2qpuB-1amyA:
75.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X2N_D_X2ND1479_1
(LANOSTEROL
14-ALPHA-DEMETHYLASE)		 1amy 1,4-ALPHA-D-GLUCAN
GLUCANOHYDROLASE
(Hordeum
vulgare) 		5 / 12 ILE A  90
PHE A 325
ALA A  32
ALA A  30
LEU A  77
 None
 1.34A 2x2nD-1amyA:
undetectable		 2x2nD-1amyA:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZJ0_A_2FAA500_2
(ADENOSYLHOMOCYSTEINA
SE)		 1amy 1,4-ALPHA-D-GLUCAN
GLUCANOHYDROLASE
(Hordeum
vulgare) 		4 / 5 THR A 290
THR A 207
HIS A 224
LEU A 228
 None
 1.37A 2zj0A-1amyA:
undetectable		 2zj0A-1amyA:
24.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A27_A_SAMA250_1
(UNCHARACTERIZED
PROTEIN MJ1557)		 1amy 1,4-ALPHA-D-GLUCAN
GLUCANOHYDROLASE
(Hordeum
vulgare) 		3 / 3 MET A 296
GLU A 204
ASN A  91
 None
None
CA  A 500 (-3.0A)
 0.96A 3a27A-1amyA:
undetectable		 3a27A-1amyA:
22.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_A_ACRA5044_1
(GLUCOSYLTRANSFERASE-
SI)		 1amy 1,4-ALPHA-D-GLUCAN
GLUCANOHYDROLASE
(Hordeum
vulgare) 		5 / 12 ARG A 177
ASP A 179
GLU A 204
HIS A 288
ASP A 289
 None
 0.60A 3aicA-1amyA:
9.5		 3aicA-1amyA:
18.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_B_ACRB5044_1
(GLUCOSYLTRANSFERASE-
SI)		 1amy 1,4-ALPHA-D-GLUCAN
GLUCANOHYDROLASE
(Hordeum
vulgare) 		5 / 12 ARG A 177
ASP A 179
GLU A 204
HIS A 288
ASP A 289
 None
 0.59A 3aicB-1amyA:
5.1		 3aicB-1amyA:
18.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_C_ACRC5044_1
(GLUCOSYLTRANSFERASE-
SI)		 1amy 1,4-ALPHA-D-GLUCAN
GLUCANOHYDROLASE
(Hordeum
vulgare) 		6 / 12 ARG A 177
ASP A 179
GLU A 204
HIS A 288
ASP A 289
TYR A  51
 None
 0.61A 3aicC-1amyA:
9.6		 3aicC-1amyA:
18.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_D_ACRD5044_1
(GLUCOSYLTRANSFERASE-
SI)		 1amy 1,4-ALPHA-D-GLUCAN
GLUCANOHYDROLASE
(Hordeum
vulgare) 		5 / 12 ARG A 177
ASP A 179
GLU A 204
HIS A 288
ASP A 289
 None
 0.66A 3aicD-1amyA:
9.5		 3aicD-1amyA:
18.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_E_ACRE5044_1
(GLUCOSYLTRANSFERASE-
SI)		 1amy 1,4-ALPHA-D-GLUCAN
GLUCANOHYDROLASE
(Hordeum
vulgare) 		5 / 12 ARG A 177
ASP A 179
GLU A 204
HIS A 288
ASP A 289
 None
 0.61A 3aicE-1amyA:
9.6		 3aicE-1amyA:
18.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_F_ACRF5044_1
(GLUCOSYLTRANSFERASE-
SI)		 1amy 1,4-ALPHA-D-GLUCAN
GLUCANOHYDROLASE
(Hordeum
vulgare) 		5 / 12 ARG A 177
ASP A 179
GLU A 204
HIS A 288
ASP A 289
 None
 0.59A 3aicF-1amyA:
9.5		 3aicF-1amyA:
18.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_G_ACRG5044_1
(GLUCOSYLTRANSFERASE-
SI)		 1amy 1,4-ALPHA-D-GLUCAN
GLUCANOHYDROLASE
(Hordeum
vulgare) 		5 / 12 ARG A 177
ASP A 179
GLU A 204
HIS A 288
ASP A 289
 None
 0.58A 3aicG-1amyA:
9.6		 3aicG-1amyA:
18.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_H_ACRH5044_1
(GLUCOSYLTRANSFERASE-
SI)		 1amy 1,4-ALPHA-D-GLUCAN
GLUCANOHYDROLASE
(Hordeum
vulgare) 		5 / 12 ARG A 177
ASP A 179
GLU A 204
HIS A 288
ASP A 289
 None
 0.65A 3aicH-1amyA:
9.6		 3aicH-1amyA:
18.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CKZ_A_ZMRA469_2
(NEURAMINIDASE)		 1amy 1,4-ALPHA-D-GLUCAN
GLUCANOHYDROLASE
(Hordeum
vulgare) 		4 / 6 ASP A 267
ARG A 225
ILE A 354
ARG A 264
 None
 1.49A 3ckzA-1amyA:
undetectable		 3ckzA-1amyA:
21.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DOU_A_SAMA1_1
(RIBOSOMAL RNA LARGE
SUBUNIT
METHYLTRANSFERASE J)		 1amy 1,4-ALPHA-D-GLUCAN
GLUCANOHYDROLASE
(Hordeum
vulgare) 		3 / 3 ASP A 396
ASP A 302
ASP A 360
 None
 0.73A 3douA-1amyA:
undetectable		 3douA-1amyA:
19.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HM1_B_J3ZB1_1
(ESTROGEN RECEPTOR)		 1amy 1,4-ALPHA-D-GLUCAN
GLUCANOHYDROLASE
(Hordeum
vulgare) 		5 / 11 LEU A  39
MET A  23
LEU A  22
GLY A  75
HIS A  78
 None
 1.21A 3hm1B-1amyA:
undetectable		 3hm1B-1amyA:
20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QOW_A_SAMA417_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE)		 1amy 1,4-ALPHA-D-GLUCAN
GLUCANOHYDROLASE
(Hordeum
vulgare) 		5 / 12 GLY A 394
GLY A 307
VAL A 372
ASP A 286
PHE A 299
 None
 1.31A 3qowA-1amyA:
undetectable		 3qowA-1amyA:
22.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_C_W9TC1005_1
(HEMOLYTIC LECTIN
CEL-III)		 1amy 1,4-ALPHA-D-GLUCAN
GLUCANOHYDROLASE
(Hordeum
vulgare) 		3 / 3 ASP A 127
GLY A 144
TYR A 130
 CA  A 502 (-2.2A)
CA  A 502 (-4.4A)
None
 0.68A 3w9tC-1amyA:
undetectable		 3w9tC-1amyA:
24.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_G_W9TG503_1
(HEMOLYTIC LECTIN
CEL-III)		 1amy 1,4-ALPHA-D-GLUCAN
GLUCANOHYDROLASE
(Hordeum
vulgare) 		3 / 3 ASP A 127
GLY A 144
TYR A 130
 CA  A 502 (-2.2A)
CA  A 502 (-4.4A)
None
 0.68A 3w9tG-1amyA:
undetectable		 3w9tG-1amyA:
24.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EVR_A_BEZA401_0
(PUTATIVE ABC
TRANSPORTER SUBUNIT,
SUBSTRATE-BINDING
COMPONENT)		 1amy 1,4-ALPHA-D-GLUCAN
GLUCANOHYDROLASE
(Hordeum
vulgare) 		5 / 11 LEU A  77
VAL A  26
PHE A 326
ALA A  32
PHE A   4
 None
 1.23A 4evrA-1amyA:
1.5		 4evrA-1amyA:
23.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GC9_A_SAMA401_0
(DIMETHYLADENOSINE
TRANSFERASE 1,
MITOCHONDRIAL)		 1amy 1,4-ALPHA-D-GLUCAN
GLUCANOHYDROLASE
(Hordeum
vulgare) 		6 / 12 GLN A   1
LEU A 312
GLY A 316
ILE A 311
VAL A 202
LEU A   3
 None
 1.18A 4gc9A-1amyA:
undetectable		 4gc9A-1amyA:
21.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LJ0_A_ACTA505_0
(NAB2)		 1amy 1,4-ALPHA-D-GLUCAN
GLUCANOHYDROLASE
(Hordeum
vulgare) 		3 / 3 LEU A 252
LYS A 249
THR A 248
 None
 0.55A 4lj0A-1amyA:
0.0		 4lj0A-1amyA:
9.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M7T_A_SAMA503_0
(BTRN)		 1amy 1,4-ALPHA-D-GLUCAN
GLUCANOHYDROLASE
(Hordeum
vulgare) 		5 / 11 TYR A 192
HIS A  92
HIS A 151
LEU A 160
LEU A 164
 None
 1.25A 4m7tA-1amyA:
2.8		 4m7tA-1amyA:
21.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NKX_A_STRA601_2
(STEROID
17-ALPHA-HYDROXYLASE
/17,20 LYASE)		 1amy 1,4-ALPHA-D-GLUCAN
GLUCANOHYDROLASE
(Hordeum
vulgare) 		4 / 6 LEU A 209
ASP A 245
VAL A 256
ALA A 255
 None
 0.98A 4nkxA-1amyA:
0.0		 4nkxA-1amyA:
22.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XE0_A_40LA1101_0
(PHOSPHATIDYLINOSITOL
4,5-BISPHOSPHATE
3-KINASE CATALYTIC
SUBUNIT DELTA
ISOFORM)		 1amy 1,4-ALPHA-D-GLUCAN
GLUCANOHYDROLASE
(Hordeum
vulgare) 		5 / 12 PRO A 318
ILE A 311
VAL A 304
ASP A 323
ILE A 334
 None
 1.26A 4xe0A-1amyA:
2.2		 4xe0A-1amyA:
17.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CSY_B_ACRB601_1
(4-ALPHA-GLUCANOTRANS
FERASE DPE1,
CHLOROPLASTIC/AMYLOP
LASTIC)		 1amy 1,4-ALPHA-D-GLUCAN
GLUCANOHYDROLASE
(Hordeum
vulgare) 		5 / 12 ARG A 177
ASP A 179
GLU A 204
HIS A 288
ASP A 289
 None
 0.31A 5csyB-1amyA:
4.8		 5csyB-1amyA:
21.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G5G_A_ACTA1231_0
(PUTATIVE XANTHINE
DEHYDROGENASE YAGR
MOLYBDENUM-BINDING
SU SUBUNIT
PUTATIVE XANTHINE
DEHYDROGENASE YAGT
IRON-SULFUR-BINDING
SUBUNIT)		 1amy 1,4-ALPHA-D-GLUCAN
GLUCANOHYDROLASE
(Hordeum
vulgare) 		3 / 3 ARG A 225
THR A 266
ASP A 267
 None
 0.93A 5g5gA-1amyA:
undetectable
5g5gB-1amyA:
undetectable		 5g5gA-1amyA:
20.78
5g5gB-1amyA:
21.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M66_D_ADND502_2
(ADENOSYLHOMOCYSTEINA
SE)		 1amy 1,4-ALPHA-D-GLUCAN
GLUCANOHYDROLASE
(Hordeum
vulgare) 		3 / 3 THR A 248
THR A 242
LEU A   3
 None
 0.59A 5m66D-1amyA:
undetectable		 5m66D-1amyA:
24.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUN_A_ACTA804_0
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1amy 1,4-ALPHA-D-GLUCAN
GLUCANOHYDROLASE
(Hordeum
vulgare) 		4 / 5 GLY A   6
GLN A   5
TRP A  38
SER A  11
 None
 1.36A 5vunA-1amyA:
0.0		 5vunA-1amyA:
22.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AG0_A_ACRA610_0
(ALPHA-AMYLASE)		 1amy 1,4-ALPHA-D-GLUCAN
GLUCANOHYDROLASE
(Hordeum
vulgare) 		7 / 12 TRP A   9
TYR A  51
HIS A  92
ASP A 179
LYS A 182
HIS A 288
ASP A 289
 None
 0.64A 6ag0A-1amyA:
36.0		 6ag0A-1amyA:
13.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AG0_A_ACRA610_0
(ALPHA-AMYLASE)		 1amy 1,4-ALPHA-D-GLUCAN
GLUCANOHYDROLASE
(Hordeum
vulgare) 		6 / 12 TYR A  51
HIS A  92
GLU A 227
ASP A 179
HIS A 288
ASP A 289
 None
 1.34A 6ag0A-1amyA:
36.0		 6ag0A-1amyA:
13.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AG0_C_ACRC608_0
(ALPHA-AMYLASE)		 1amy 1,4-ALPHA-D-GLUCAN
GLUCANOHYDROLASE
(Hordeum
vulgare) 		5 / 12 TRP A   9
ASP A 179
LYS A 182
HIS A 288
ASP A 289
 None
 0.52A 6ag0C-1amyA:
36.1		 6ag0C-1amyA:
13.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AG0_C_ACRC608_1
(ALPHA-AMYLASE)		 1amy 1,4-ALPHA-D-GLUCAN
GLUCANOHYDROLASE
(Hordeum
vulgare) 		3 / 3 TYR A  19
ALA A  76
LEU A  77
 None
 0.54A 6ag0C-1amyA:
36.1		 6ag0C-1amyA:
13.72