SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1anu'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JAY_A_SAMA1102_1
(STRUCTURAL PROTEIN
VP3)		 1anu COHESIN-2
(Ruminiclostridiu
m
thermocellum) 		3 / 3 ARG A  38
ASP A 133
ASP A 114
 None
 0.88A 3jayA-1anuA:
0.0		 3jayA-1anuA:
7.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JB2_A_SAMA1101_0
(STRUCTURAL PROTEIN
VP3)		 1anu COHESIN-2
(Ruminiclostridiu
m
thermocellum) 		5 / 12 SER A  63
PRO A  58
VAL A  25
ILE A  30
ASN A  32
 None
 1.27A 3jb2A-1anuA:
0.0		 3jb2A-1anuA:
7.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JB2_A_SAMA1102_1
(STRUCTURAL PROTEIN
VP3)		 1anu COHESIN-2
(Ruminiclostridiu
m
thermocellum) 		3 / 3 ARG A  38
ASP A 133
ASP A 114
 None
 0.72A 3jb2A-1anuA:
0.0		 3jb2A-1anuA:
7.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JB3_A_SAMA1102_1
(STRUCTURAL PROTEIN
VP3)		 1anu COHESIN-2
(Ruminiclostridiu
m
thermocellum) 		3 / 3 ARG A  38
ASP A 133
ASP A 114
 None
 0.72A 3jb3A-1anuA:
0.0		 3jb3A-1anuA:
7.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3Q_B_9PLB501_1
(CYTOCHROME P450 2A6)		 1anu COHESIN-2
(Ruminiclostridiu
m
thermocellum) 		5 / 10 PHE A  35
PHE A 119
PHE A  96
ILE A   5
PHE A  37
 None
 1.08A 3t3qB-1anuA:
undetectable		 3t3qB-1anuA:
16.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3Q_C_9PLC501_1
(CYTOCHROME P450 2A6)		 1anu COHESIN-2
(Ruminiclostridiu
m
thermocellum) 		5 / 10 PHE A  35
PHE A 119
PHE A  96
ILE A   5
PHE A  37
 None
 1.08A 3t3qC-1anuA:
undetectable		 3t3qC-1anuA:
16.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3Q_D_9PLD501_1
(CYTOCHROME P450 2A6)		 1anu COHESIN-2
(Ruminiclostridiu
m
thermocellum) 		5 / 10 PHE A  35
PHE A 119
PHE A  96
ILE A   5
PHE A  37
 None
 1.07A 3t3qD-1anuA:
undetectable		 3t3qD-1anuA:
16.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JLT_A_8PRA505_1
(CYTOCHROME P450 2B4)		 1anu COHESIN-2
(Ruminiclostridiu
m
thermocellum) 		4 / 8 ILE A  30
VAL A  25
PRO A  26
VAL A 129
 None
 0.73A 4jltA-1anuA:
undetectable		 4jltA-1anuA:
18.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HW4_B_SAMB801_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE I)		 1anu COHESIN-2
(Ruminiclostridiu
m
thermocellum) 		5 / 11 ILE A  46
GLY A  48
ASP A  50
ALA A 101
LEU A  44
 None
 1.34A 5hw4B-1anuA:
undetectable		 5hw4B-1anuA:
19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DH0_A_017A101_2
(PROTEASE)		 1anu COHESIN-2
(Ruminiclostridiu
m
thermocellum) 		3 / 3 LEU A  78
ASP A  50
ILE A  99
 None
 0.60A 6dh0B-1anuA:
0.0		 6dh0B-1anuA:
23.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EMU_B_SAMB301_0
(TRNA
(GUANINE(9)-/ADENINE
(9)-N1)-METHYLTRANSF
ERASE)		 1anu COHESIN-2
(Ruminiclostridiu
m
thermocellum) 		5 / 12 ILE A  47
GLY A  48
ILE A  49
VAL A   8
VAL A 136
 None
 1.03A 6emuB-1anuA:
undetectable		 6emuB-1anuA:
18.27