SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1aoc'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ONI_A_BEZA501_0
(14.5 KDA
TRANSLATIONAL
INHIBITOR PROTEIN)		 1aoc COAGULOGEN
(Tachypleus
tridentatus) 		4 / 7 PHE A  51
ALA A 116
ILE A  30
GLU A  31
 None
 0.92A 1oniA-1aocA:
undetectable
1oniB-1aocA:
undetectable		 1oniA-1aocA:
19.78
1oniB-1aocA:
19.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ONI_D_BEZD507_0
(14.5 KDA
TRANSLATIONAL
INHIBITOR PROTEIN)		 1aoc COAGULOGEN
(Tachypleus
tridentatus) 		4 / 7 PHE A  51
ALA A 116
ILE A  30
GLU A  31
 None
 0.94A 1oniD-1aocA:
undetectable
1oniF-1aocA:
undetectable		 1oniD-1aocA:
19.78
1oniF-1aocA:
19.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T6Z_B_RBFB596_1
(RIBOFLAVIN
KINASE/FMN
ADENYLYLTRANSFERASE)		 1aoc COAGULOGEN
(Tachypleus
tridentatus) 		5 / 11 VAL A  98
VAL A 109
TYR A 152
GLU A  96
ILE A  30
 None
 1.19A 1t6zB-1aocA:
undetectable		 1t6zB-1aocA:
20.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QF1_A_PZEA6951_1
(LACTOPEROXIDASE)		 1aoc COAGULOGEN
(Tachypleus
tridentatus) 		3 / 3 HIS A 125
ARG A  74
GLU A  71
 None
 1.12A 3qf1A-1aocA:
undetectable		 3qf1A-1aocA:
14.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R9T_C_BEZC264_0
(ECHA1_1)		 1aoc COAGULOGEN
(Tachypleus
tridentatus) 		4 / 5 ALA A  33
GLU A  31
GLU A  35
ALA A 113
 None
 1.05A 3r9tC-1aocA:
undetectable		 3r9tC-1aocA:
21.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A1R_A_STRA600_1
(CYTOCHROME P450 3A4)		 1aoc COAGULOGEN
(Tachypleus
tridentatus) 		4 / 5 PHE A  51
PHE A 159
PHE A  57
VAL A  34
 None
 1.05A 5a1rA-1aocA:
undetectable		 5a1rA-1aocA:
16.01