SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1aoh'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CD2_A_FOLA307_0
(DIHYDROFOLATE
REDUCTASE)		 1aoh CELLULOSOMAL-SCAFFOL
DING PROTEIN A
(Ruminiclostridiu
m
thermocellum) 		5 / 12 ILE A  54
ALA A  72
PHE A  82
PHE A 121
ILE A 104
 None
 1.10A 1cd2A-1aohA:
undetectable		 1cd2A-1aohA:
19.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QBN_A_CAMA442_0
(CYTOCHROME P450-CAM)		 1aoh CELLULOSOMAL-SCAFFOL
DING PROTEIN A
(Ruminiclostridiu
m
thermocellum) 		4 / 7 VAL A 105
VAL A  13
ASP A  11
VAL A 144
 None
 0.92A 2qbnA-1aohA:
undetectable		 2qbnA-1aohA:
17.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XRZ_B_ACTB1463_0
(DEOXYRIBODIPYRIMIDIN
E PHOTOLYASE)		 1aoh CELLULOSOMAL-SCAFFOL
DING PROTEIN A
(Ruminiclostridiu
m
thermocellum) 		4 / 7 ILE A 104
ALA A 106
VAL A  21
GLY A 143
 None
 0.80A 2xrzB-1aohA:
undetectable		 2xrzB-1aohA:
16.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_B_TFPB201_1
(PROTEIN S100-A4)		 1aoh CELLULOSOMAL-SCAFFOL
DING PROTEIN A
(Ruminiclostridiu
m
thermocellum) 		4 / 8 ILE A  23
PHE A  27
PHE A  82
PHE A  40
 None
 1.03A 3ko0B-1aohA:
undetectable
3ko0J-1aohA:
undetectable		 3ko0B-1aohA:
19.21
3ko0J-1aohA:
19.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_K_TFPK201_1
(PROTEIN S100-A4)		 1aoh CELLULOSOMAL-SCAFFOL
DING PROTEIN A
(Ruminiclostridiu
m
thermocellum) 		4 / 8 ILE A  23
PHE A  27
PHE A  82
PHE A  40
 None
 1.05A 3ko0K-1aohA:
undetectable
3ko0S-1aohA:
undetectable		 3ko0K-1aohA:
19.21
3ko0S-1aohA:
19.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FPD_B_PZAB1385_0
(HEAT SHOCK-RELATED
70KDA PROTEIN 2)		 1aoh CELLULOSOMAL-SCAFFOL
DING PROTEIN A
(Ruminiclostridiu
m
thermocellum) 		4 / 7 ASN A 114
VAL A 146
ALA A  15
GLY A  18
 None
 0.90A 5fpdB-1aohA:
undetectable		 5fpdB-1aohA:
17.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VYH_A_FOLA409_0
(S PROTEIN)		 1aoh CELLULOSOMAL-SCAFFOL
DING PROTEIN A
(Ruminiclostridiu
m
thermocellum) 		5 / 10 PRO A  65
PRO A  56
ALA A  85
GLY A  89
THR A  90
 None
 1.36A 5vyhA-1aohA:
0.0		 5vyhA-1aohA:
18.84