SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1aok'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1SV9_A_DIFA701_1
(PHOSPHOLIPASE A2)		 1aok VIPOXIN COMPLEX
(Vipera
ammodytes) 		4 / 8 LEU B   2
GLY B  30
HIS B  48
PHE B 106
 None
ACT  B 134 (-3.7A)
ACT  B 134 (-3.6A)
ACT  B 134 (-4.8A)
 0.63A 1sv9A-1aokB:
20.8		 1sv9A-1aokB:
56.35
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1TH6_A_OINA401_1
(PHOSPHOLIPASE A2)		 1aok VIPOXIN COMPLEX
(Vipera
ammodytes) 		6 / 7 GLY B  30
HIS B  48
ASP B  49
TYR B  52
PRO B  68
LYS B  69
 ACT  B 134 (-3.7A)
ACT  B 134 (-3.6A)
ACT  B 134 ( 4.9A)
None
None
None
 1.01A 1th6A-1aokB:
20.7		 1th6A-1aokB:
56.35
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1Y4L_B_SVRB301_1
(PHOSPHOLIPASE A2
HOMOLOG 2)		 1aok VIPOXIN COMPLEX
(Vipera
ammodytes) 		5 / 12 LEU B   2
GLY B  30
TYR B  52
PRO B  68
LYS B  69
 None
ACT  B 134 (-3.7A)
None
None
None
 0.75A 1y4lA-1aokB:
19.8		 1y4lA-1aokB:
49.60
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2ARM_A_OINA401_1
(PHOSPHOLIPASE A2
VRV-PL-VIIIA)		 1aok VIPOXIN COMPLEX
(Vipera
ammodytes) 		6 / 7 GLY B  30
HIS B  48
ASP B  49
TYR B  52
PRO B  68
LYS B  69
 ACT  B 134 (-3.7A)
ACT  B 134 (-3.6A)
ACT  B 134 ( 4.9A)
None
None
None
 1.01A 2armA-1aokB:
20.8		 2armA-1aokB:
56.35
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2B17_A_DIFA701_1
(PHOSPHOLIPASE A2
VRV-PL-VIIIA)		 1aok VIPOXIN COMPLEX
(Vipera
ammodytes) 		5 / 10 LEU B   2
GLY B  30
HIS B  48
ASP B  49
PHE B 106
 None
ACT  B 134 (-3.7A)
ACT  B 134 (-3.6A)
ACT  B 134 ( 4.9A)
ACT  B 134 (-4.8A)
 0.63A 2b17A-1aokB:
20.7		 2b17A-1aokB:
56.35
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2DPZ_A_TYLA2001_1
(PHOSPHOLIPASE A2
VRV-PL-VIIIA)		 1aok VIPOXIN COMPLEX
(Vipera
ammodytes) 		4 / 6 LEU B   2
HIS B  48
ASP B  49
TYR B  52
 None
ACT  B 134 (-3.6A)
ACT  B 134 ( 4.9A)
None
 0.32A 2dpzA-1aokB:
21.1		 2dpzA-1aokB:
56.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WEY_B_EV1B1771_1
(CAMP AND
CAMP-INHIBITED CGMP
3', 5'-CYCLIC
PHOSPHODIESTERASE)		 1aok VIPOXIN COMPLEX
(Vipera
ammodytes) 		4 / 8 LEU B  13
ILE B  82
TYR B  75
PHE B  77
 None
 0.84A 2weyB-1aokB:
undetectable		 2weyB-1aokB:
14.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3FO7_A_IMNA301_1
(PHOSPHOLIPASE A2
VRV-PL-VIIIA)		 1aok VIPOXIN COMPLEX
(Vipera
ammodytes) 		4 / 5 HIS B  48
ASP B  49
TYR B  52
PRO B  68
 ACT  B 134 (-3.6A)
ACT  B 134 ( 4.9A)
None
None
 0.50A 3fo7A-1aokB:
20.9		 3fo7A-1aokB:
56.35
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3H1X_A_IMNA301_1
(PHOSPHOLIPASE A2
VRV-PL-VIIIA)		 1aok VIPOXIN COMPLEX
(Vipera
ammodytes) 		4 / 5 HIS B  48
ASP B  49
TYR B  52
PRO B  68
 ACT  B 134 (-3.6A)
ACT  B 134 ( 4.9A)
None
None
 0.43A 3h1xA-1aokB:
20.9		 3h1xA-1aokB:
56.35
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3OSH_A_OINA5811_1
(PHOSPHOLIPASE A2
ISOFORM 3)		 1aok VIPOXIN COMPLEX
(Vipera
ammodytes) 		5 / 9 LEU B   2
PHE B   5
ILE B   9
GLY B  30
HIS B  48
 None
ACT  B 134 (-4.6A)
None
ACT  B 134 (-3.7A)
ACT  B 134 (-3.6A)
 0.41A 3oshA-1aokB:
19.7		 3oshA-1aokB:
43.80
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3R0L_D_ACTD127_0
(PHOSPHOLIPASE A2 CB)		 1aok VIPOXIN COMPLEX
(Vipera
ammodytes) 		4 / 5 PHE B   5
ILE B   9
GLY B  30
HIS B  48
 ACT  B 134 (-4.6A)
None
ACT  B 134 (-3.7A)
ACT  B 134 (-3.6A)
 0.46A 3r0lD-1aokB:
20.6		 3r0lD-1aokB:
57.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KMD_C_6UBC1304_1
(ION TRANSPORT
PROTEIN)		 1aok VIPOXIN COMPLEX
(Vipera
ammodytes) 		4 / 5 TYR B  75
ILE B  82
LEU B   2
PHE B   5
 None
None
None
ACT  B 134 (-4.6A)
 0.91A 5kmdC-1aokB:
0.0
5kmdD-1aokB:
undetectable		 5kmdC-1aokB:
14.04
5kmdD-1aokB:
14.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6C2M_C_SUEC1203_0
(NS3 PROTEASE)		 1aok VIPOXIN COMPLEX
(Vipera
ammodytes) 		5 / 12 ARG B 100
PHE B   5
ALA B 103
ALA B 102
VAL B 101
 None
ACT  B 134 (-4.6A)
None
ACT  B 134 ( 4.7A)
None
 1.04A 6c2mC-1aokB:
undetectable		 6c2mC-1aokB:
19.69