SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1aql'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1AX9_A_EDRA999_1
(ACETYLCHOLINESTERASE)		 1aql BILE-SALT ACTIVATED
LIPASE
(Bos
taurus) 		4 / 8 GLU A 193
SER A 194
PHE A 324
HIS A 435
 None
 0.64A 1ax9A-1aqlA:
48.2		 1ax9A-1aqlA:
33.63
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1AX9_A_EDRA999_1
(ACETYLCHOLINESTERASE)		 1aql BILE-SALT ACTIVATED
LIPASE
(Bos
taurus) 		4 / 8 GLY A 107
GLU A 193
PHE A 324
HIS A 435
 None
 0.62A 1ax9A-1aqlA:
48.2		 1ax9A-1aqlA:
33.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DB1_A_VDXA428_2
(VITAMIN D NUCLEAR
RECEPTOR)		 1aql BILE-SALT ACTIVATED
LIPASE
(Bos
taurus) 		4 / 6 LEU A 164
ILE A 102
TRP A 103
TYR A 105
 None
 1.14A 1db1A-1aqlA:
undetectable		 1db1A-1aqlA:
20.70
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1DX6_A_GNTA602_1
(ACETYLCHOLINESTERASE)		 1aql BILE-SALT ACTIVATED
LIPASE
(Bos
taurus) 		6 / 12 GLY A 106
GLY A 107
SER A 194
TRP A 227
PHE A 324
HIS A 435
 None
 0.56A 1dx6A-1aqlA:
51.2		 1dx6A-1aqlA:
33.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E7C_A_HLTA4008_1
(SERUM ALBUMIN)		 1aql BILE-SALT ACTIVATED
LIPASE
(Bos
taurus) 		4 / 8 LEU A 258
LEU A 234
ALA A 237
LYS A 238
 None
 0.68A 1e7cA-1aqlA:
0.0		 1e7cA-1aqlA:
22.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FOH_C_IPHC802_0
(PHENOL HYDROXYLASE)		 1aql BILE-SALT ACTIVATED
LIPASE
(Bos
taurus) 		5 / 10 GLY A 197
VAL A 200
ILE A 104
TYR A 143
GLY A 106
 None
 1.38A 1fohC-1aqlA:
0.0		 1fohC-1aqlA:
23.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTI_F_CCSF47_0
(GLUTATHIONE
S-TRANSFERASE)		 1aql BILE-SALT ACTIVATED
LIPASE
(Bos
taurus) 		4 / 5 THR A 531
LEU A 529
GLY A 356
TYR A 526
 None
 1.21A 1gtiF-1aqlA:
0.0		 1gtiF-1aqlA:
17.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HPK_A_ACAA80_1
(PLASMINOGEN)		 1aql BILE-SALT ACTIVATED
LIPASE
(Bos
taurus) 		4 / 6 PRO A 428
ASN A 317
ASP A 437
TYR A 427
 None
 1.42A 1hpkA-1aqlA:
0.0		 1hpkA-1aqlA:
8.69
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1MAA_C_DMEC997_1
(ACETYLCHOLINESTERASE)		 1aql BILE-SALT ACTIVATED
LIPASE
(Bos
taurus) 		5 / 12 GLY A 107
TYR A 125
SER A 194
PHE A 324
HIS A 435
 None
 0.73A 1maaC-1aqlA:
46.9		 1maaC-1aqlA:
33.92
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1MAA_D_DMED999_1
(ACETYLCHOLINESTERASE)		 1aql BILE-SALT ACTIVATED
LIPASE
(Bos
taurus) 		4 / 8 GLY A 107
GLU A 193
SER A 194
HIS A 435
 None
 0.67A 1maaD-1aqlA:
43.5		 1maaD-1aqlA:
33.92
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1MX1_C_THAC3_1
(LIVER
CARBOXYLESTERASE I)		 1aql BILE-SALT ACTIVATED
LIPASE
(Bos
taurus) 		5 / 12 GLY A 107
SER A 194
LEU A 285
PHE A 393
HIS A 435
 None
 0.70A 1mx1C-1aqlA:
48.2		 1mx1C-1aqlA:
35.38
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1MX1_E_THAE5_1
(LIVER
CARBOXYLESTERASE I)		 1aql BILE-SALT ACTIVATED
LIPASE
(Bos
taurus) 		5 / 12 GLY A 107
SER A 194
LEU A 285
PHE A 393
HIS A 435
 None
 0.82A 1mx1E-1aqlA:
48.4		 1mx1E-1aqlA:
35.38
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1MX1_F_THAF6_1
(LIVER
CARBOXYLESTERASE I)		 1aql BILE-SALT ACTIVATED
LIPASE
(Bos
taurus) 		5 / 12 GLY A 107
SER A 194
LEU A 285
PHE A 393
HIS A 435
 None
 0.70A 1mx1F-1aqlA:
48.2		 1mx1F-1aqlA:
35.38
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1QTI_A_GNTA600_1
(ACETYLCHOLINESTERASE)		 1aql BILE-SALT ACTIVATED
LIPASE
(Bos
taurus) 		6 / 12 GLY A 106
GLY A 107
GLU A 193
SER A 194
PHE A 324
HIS A 435
 None
 0.63A 1qtiA-1aqlA:
49.8		 1qtiA-1aqlA:
33.63
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1QTI_A_GNTA600_1
(ACETYLCHOLINESTERASE)		 1aql BILE-SALT ACTIVATED
LIPASE
(Bos
taurus) 		6 / 12 GLY A 106
GLY A 107
GLU A 193
SER A 194
PHE A 324
HIS A 435
 None
 0.85A 1qtiA-1aqlA:
49.8		 1qtiA-1aqlA:
33.63
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1W6R_A_GNTA1536_1
(ACETYLCHOLINESTERASE)		 1aql BILE-SALT ACTIVATED
LIPASE
(Bos
taurus) 		5 / 12 GLY A 106
GLY A 107
SER A 194
PHE A 324
HIS A 435
 None
 0.55A 1w6rA-1aqlA:
51.1		 1w6rA-1aqlA:
33.63
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1W6R_A_GNTA1536_1
(ACETYLCHOLINESTERASE)		 1aql BILE-SALT ACTIVATED
LIPASE
(Bos
taurus) 		5 / 12 GLY A 106
GLY A 107
SER A 194
PHE A 324
HIS A 435
 None
 0.88A 1w6rA-1aqlA:
51.1		 1w6rA-1aqlA:
33.63
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1W76_A_GNTA1538_1
(ACETYLCHOLINESTERASE)		 1aql BILE-SALT ACTIVATED
LIPASE
(Bos
taurus) 		5 / 11 GLY A 106
GLY A 107
GLU A 193
SER A 194
HIS A 435
 None
 1.27A 1w76A-1aqlA:
50.2		 1w76A-1aqlA:
33.63
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1W76_A_GNTA1538_1
(ACETYLCHOLINESTERASE)		 1aql BILE-SALT ACTIVATED
LIPASE
(Bos
taurus) 		5 / 11 GLY A 107
GLU A 193
SER A 194
PHE A 324
HIS A 435
 None
 0.63A 1w76A-1aqlA:
50.2		 1w76A-1aqlA:
33.63
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1W76_B_GNTB1538_1
(ACETYLCHOLINESTERASE)		 1aql BILE-SALT ACTIVATED
LIPASE
(Bos
taurus) 		6 / 10 GLY A 106
GLY A 107
GLU A 193
SER A 194
PHE A 324
HIS A 435
 None
 0.54A 1w76B-1aqlA:
50.2		 1w76B-1aqlA:
33.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WG8_B_SAMB3141_0
(PREDICTED
S-ADENOSYLMETHIONINE
-DEPENDENT
METHYLTRANSFERASE)		 1aql BILE-SALT ACTIVATED
LIPASE
(Bos
taurus) 		5 / 12 GLY A 106
GLY A 107
GLY A 112
GLN A 219
PHE A 191
 None
 1.15A 1wg8B-1aqlA:
undetectable		 1wg8B-1aqlA:
20.75
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1YAJ_C_BEZC5013_0
(CES1 PROTEIN)		 1aql BILE-SALT ACTIVATED
LIPASE
(Bos
taurus) 		5 / 8 GLY A 106
GLY A 107
SER A 194
ALA A 195
HIS A 435
 None
 1.00A 1yajC-1aqlA:
47.3		 1yajC-1aqlA:
35.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1YAJ_C_BEZC5013_0
(CES1 PROTEIN)		 1aql BILE-SALT ACTIVATED
LIPASE
(Bos
taurus) 		6 / 8 GLY A 106
GLY A 107
SER A 194
ALA A 195
LEU A 285
HIS A 435
 None
 1.26A 1yajC-1aqlA:
47.3		 1yajC-1aqlA:
35.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZQ9_A_SAMA4000_0
(PROBABLE
DIMETHYLADENOSINE
TRANSFERASE)		 1aql BILE-SALT ACTIVATED
LIPASE
(Bos
taurus) 		5 / 12 HIS A 168
LEU A  83
LEU A  81
ILE A 102
SER A 206
 None
 1.27A 1zq9A-1aqlA:
undetectable		 1zq9A-1aqlA:
20.96
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2ACE_A_ACHA998_0
(ACETYLCHOLINESTERASE)		 1aql BILE-SALT ACTIVATED
LIPASE
(Bos
taurus) 		5 / 9 GLY A 106
GLY A 107
SER A 194
ALA A 195
HIS A 435
 None
 0.95A 2aceA-1aqlA:
53.0		 2aceA-1aqlA:
33.63
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2ACE_A_ACHA998_0
(ACETYLCHOLINESTERASE)		 1aql BILE-SALT ACTIVATED
LIPASE
(Bos
taurus) 		5 / 9 GLY A 107
SER A 194
ALA A 195
TRP A 227
HIS A 435
 None
 0.64A 2aceA-1aqlA:
53.0		 2aceA-1aqlA:
33.63
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2ACK_A_EDRA999_1
(ACETYLCHOLINESTERASE)		 1aql BILE-SALT ACTIVATED
LIPASE
(Bos
taurus) 		4 / 7 GLU A 193
SER A 194
PHE A 324
HIS A 435
 None
 0.65A 2ackA-1aqlA:
51.5		 2ackA-1aqlA:
33.63
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2ACK_A_EDRA999_1
(ACETYLCHOLINESTERASE)		 1aql BILE-SALT ACTIVATED
LIPASE
(Bos
taurus) 		4 / 7 GLY A 107
GLU A 193
PHE A 324
HIS A 435
 None
 0.70A 2ackA-1aqlA:
51.5		 2ackA-1aqlA:
33.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AVV_A_MK1A901_2
(POL POLYPROTEIN)		 1aql BILE-SALT ACTIVATED
LIPASE
(Bos
taurus) 		3 / 3 ASP A 506
VAL A 484
PRO A 477
 None
 0.78A 2avvA-1aqlA:
0.0		 2avvA-1aqlA:
14.16
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2HA4_A_ACHA546_0
(ACETYLCHOLINESTERASE)		 1aql BILE-SALT ACTIVATED
LIPASE
(Bos
taurus) 		4 / 8 TYR A 125
GLU A 193
PHE A 324
HIS A 435
 None
 0.45A 2ha4A-1aqlA:
46.7		 2ha4A-1aqlA:
33.86
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2HA4_A_ACTA544_0
(ACETYLCHOLINESTERASE)		 1aql BILE-SALT ACTIVATED
LIPASE
(Bos
taurus) 		4 / 8 GLY A 107
ALA A 195
TRP A 227
HIS A 435
 None
 0.50A 2ha4A-1aqlA:
46.7		 2ha4A-1aqlA:
33.86
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2HA4_B_ACTB601_0
(ACETYLCHOLINESTERASE)		 1aql BILE-SALT ACTIVATED
LIPASE
(Bos
taurus) 		4 / 7 GLY A 107
ALA A 195
TRP A 227
HIS A 435
 None
 0.49A 2ha4B-1aqlA:
49.9		 2ha4B-1aqlA:
33.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q63_A_1UNA1001_4
(PROTEASE RETROPEPSIN)		 1aql BILE-SALT ACTIVATED
LIPASE
(Bos
taurus) 		3 / 3 ASP A  79
ASN A  77
THR A 267
 None
 0.80A 2q63B-1aqlA:
0.0		 2q63B-1aqlA:
12.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QD3_A_CHDA501_0
(FERROCHELATASE)		 1aql BILE-SALT ACTIVATED
LIPASE
(Bos
taurus) 		5 / 11 LEU A 387
LEU A 347
ILE A 391
THR A 277
VAL A 353
 None
None
TCH  A 602 (-3.5A)
None
TCH  A 602 (-3.7A)
 1.26A 2qd3A-1aqlA:
undetectable		 2qd3A-1aqlA:
21.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A25_A_SAMA279_1
(UNCHARACTERIZED
PROTEIN PH0793)		 1aql BILE-SALT ACTIVATED
LIPASE
(Bos
taurus) 		3 / 3 MET A 111
GLU A 193
ASP A 437
 None
 0.99A 3a25A-1aqlA:
undetectable		 3a25A-1aqlA:
18.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MB5_A_SAMA301_1
(SAM-DEPENDENT
METHYLTRANSFERASE)		 1aql BILE-SALT ACTIVATED
LIPASE
(Bos
taurus) 		4 / 4 GLY A 321
GLU A 388
ASP A 390
ASP A 434
 None
 1.39A 3mb5A-1aqlA:
undetectable		 3mb5A-1aqlA:
19.32
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3O9M_A_BEZA999_0
(CHOLINESTERASE)		 1aql BILE-SALT ACTIVATED
LIPASE
(Bos
taurus) 		5 / 7 GLY A 107
SER A 194
TRP A 227
PHE A 393
HIS A 435
 None
 0.81A 3o9mA-1aqlA:
52.2		 3o9mA-1aqlA:
32.06
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3O9M_B_BEZB999_0
(CHOLINESTERASE)		 1aql BILE-SALT ACTIVATED
LIPASE
(Bos
taurus) 		4 / 6 GLY A 107
SER A 194
TRP A 227
HIS A 435
 None
 0.82A 3o9mB-1aqlA:
52.2		 3o9mB-1aqlA:
32.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3C_A_017A201_1
(HIV-1 PROTEASE)		 1aql BILE-SALT ACTIVATED
LIPASE
(Bos
taurus) 		4 / 7 ASP A 318
GLY A 432
ALA A 433
ASP A 437
 None
 0.74A 3t3cA-1aqlA:
undetectable		 3t3cA-1aqlA:
11.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UG8_A_IMNA2001_2
(ALDO-KETO REDUCTASE
FAMILY 1 MEMBER C3)		 1aql BILE-SALT ACTIVATED
LIPASE
(Bos
taurus) 		3 / 3 TYR A 526
GLU A 365
TYR A 364
 None
NAG  A 600 ( 4.3A)
NAG  A 600 ( 4.4A)
 0.88A 3ug8A-1aqlA:
1.6		 3ug8A-1aqlA:
20.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W67_B_VIVB301_0
(ALPHA-TOCOPHEROL
TRANSFER PROTEIN)		 1aql BILE-SALT ACTIVATED
LIPASE
(Bos
taurus) 		5 / 12 ILE A 313
TRP A 468
TRP A 488
ILE A 501
PHE A 324
 None
 1.02A 3w67B-1aqlA:
undetectable		 3w67B-1aqlA:
19.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E1G_A_LNLA701_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 1aql BILE-SALT ACTIVATED
LIPASE
(Bos
taurus) 		5 / 12 ASN A 209
ILE A 213
GLY A 197
ALA A 198
LEU A 205
 None
 1.01A 4e1gA-1aqlA:
0.0		 4e1gA-1aqlA:
20.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E1G_A_LNLA701_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 1aql BILE-SALT ACTIVATED
LIPASE
(Bos
taurus) 		5 / 12 ILE A 213
GLY A 197
ALA A 198
SER A 201
LEU A 205
 None
 0.78A 4e1gA-1aqlA:
0.0		 4e1gA-1aqlA:
20.36
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4EY6_A_GNTA604_1
(ACETYLCHOLINESTERASE)		 1aql BILE-SALT ACTIVATED
LIPASE
(Bos
taurus) 		5 / 12 GLY A 106
GLY A 107
SER A 194
PHE A 324
HIS A 435
 None
 0.49A 4ey6A-1aqlA:
50.3		 4ey6A-1aqlA:
33.87
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4EY6_B_GNTB605_1
(ACETYLCHOLINESTERASE)		 1aql BILE-SALT ACTIVATED
LIPASE
(Bos
taurus) 		6 / 12 GLY A 106
GLY A 107
GLU A 193
SER A 194
PHE A 324
HIS A 435
 None
 0.47A 4ey6B-1aqlA:
44.0		 4ey6B-1aqlA:
33.87
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4EY6_B_GNTB605_1
(ACETYLCHOLINESTERASE)		 1aql BILE-SALT ACTIVATED
LIPASE
(Bos
taurus) 		6 / 12 GLY A 106
GLY A 107
GLU A 193
SER A 194
PHE A 324
HIS A 435
 None
 0.92A 4ey6B-1aqlA:
44.0		 4ey6B-1aqlA:
33.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IJI_F_BEZF501_0
(GLUTATHIONE
S-TRANSFERASE-LIKE
PROTEIN YIBF)		 1aql BILE-SALT ACTIVATED
LIPASE
(Bos
taurus) 		4 / 8 ASN A 142
ALA A 113
SER A 114
TYR A 125
 None
 1.10A 4ijiF-1aqlA:
0.0		 4ijiF-1aqlA:
17.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IJI_H_BEZH501_0
(GLUTATHIONE
S-TRANSFERASE-LIKE
PROTEIN YIBF)		 1aql BILE-SALT ACTIVATED
LIPASE
(Bos
taurus) 		4 / 7 ASN A 142
ALA A 113
SER A 114
TYR A 125
 None
 1.11A 4ijiH-1aqlA:
undetectable		 4ijiH-1aqlA:
17.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LV9_B_20JB601_1
(NICOTINAMIDE
PHOSPHORIBOSYLTRANSF
ERASE)		 1aql BILE-SALT ACTIVATED
LIPASE
(Bos
taurus) 		4 / 7 PHE A 324
ASP A 320
SER A 220
ALA A 436
 None
 0.94A 4lv9A-1aqlA:
undetectable
4lv9B-1aqlA:
undetectable		 4lv9A-1aqlA:
21.82
4lv9B-1aqlA:
21.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OLF_A_HFGA802_0
(PROLINE--TRNA LIGASE)		 1aql BILE-SALT ACTIVATED
LIPASE
(Bos
taurus) 		5 / 12 VAL A 460
GLU A 193
HIS A 435
THR A 397
GLY A 221
 None
 1.22A 4olfA-1aqlA:
undetectable		 4olfA-1aqlA:
21.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ECN_D_LEUD602_0
(JASMONIC ACID-AMIDO
SYNTHETASE JAR1)		 1aql BILE-SALT ACTIVATED
LIPASE
(Bos
taurus) 		4 / 8 ALA A 362
THR A 363
VAL A 366
TYR A 367
 None
 0.74A 5ecnD-1aqlA:
1.2		 5ecnD-1aqlA:
21.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IZF_E_AZ1E2_1
(CAMP-DEPENDENT
PROTEIN KINASE
CATALYTIC SUBUNIT
ALPHA
6J9-ZEU-DAR-ACA-DAR-
NH2)		 1aql BILE-SALT ACTIVATED
LIPASE
(Bos
taurus) 		5 / 7 GLY A 223
GLY A 221
SER A 220
PHE A 393
LEU A 392
 None
 1.17A 5izfA-1aqlA:
undetectable		 5izfA-1aqlA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KC0_A_RBFA303_2
(RIBOFLAVIN
TRANSPORTER RIBU)		 1aql BILE-SALT ACTIVATED
LIPASE
(Bos
taurus) 		3 / 3 LYS A   2
LEU A  20
ILE A  29
 None
 0.77A 5kc0A-1aqlA:
0.0		 5kc0A-1aqlA:
19.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L4I_B_6J3B201_0
(TRANSTHYRETIN)		 1aql BILE-SALT ACTIVATED
LIPASE
(Bos
taurus) 		4 / 6 ALA A 307
LEU A 303
SER A 206
THR A 204
 None
 1.27A 5l4iB-1aqlA:
0.0		 5l4iB-1aqlA:
18.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LG3_F_Z80F401_1
(GAMMA-AMINOBUTYRIC-A
CID RECEPTOR SUBUNIT
BETA-1)		 1aql BILE-SALT ACTIVATED
LIPASE
(Bos
taurus) 		5 / 10 ILE A 102
ILE A 188
VAL A 139
ASP A 184
ILE A 178
 None
 1.30A 5lg3F-1aqlA:
0.0		 5lg3F-1aqlA:
21.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LG3_G_Z80G401_1
(GAMMA-AMINOBUTYRIC-A
CID RECEPTOR SUBUNIT
BETA-1)		 1aql BILE-SALT ACTIVATED
LIPASE
(Bos
taurus) 		5 / 10 ILE A 102
ILE A 188
VAL A 139
ASP A 184
ILE A 178
 None
 1.23A 5lg3G-1aqlA:
0.0		 5lg3G-1aqlA:
21.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5O96_G_SAMG501_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE E)		 1aql BILE-SALT ACTIVATED
LIPASE
(Bos
taurus) 		5 / 11 LEU A 151
GLY A 146
LEU A 258
ARG A 264
THR A 267
 None
 1.03A 5o96G-1aqlA:
undetectable		 5o96G-1aqlA:
18.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_H_EZLH303_1
(ALPHA-CARBONIC
ANHYDRASE)		 1aql BILE-SALT ACTIVATED
LIPASE
(Bos
taurus) 		4 / 8 VAL A 222
LEU A 205
THR A 204
ALA A 307
 None
 0.88A 5tt3H-1aqlA:
undetectable		 5tt3H-1aqlA:
17.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X7P_A_ACRA1431_1
(GLYCOSIDE HYDROLASE
FAMILY 31
ALPHA-GLUCOSIDASE)		 1aql BILE-SALT ACTIVATED
LIPASE
(Bos
taurus) 		4 / 7 HIS A 435
ASP A 438
GLY A 315
ASN A 317
 None
 1.12A 5x7pA-1aqlA:
0.1		 5x7pA-1aqlA:
17.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XIQ_A_HFGA1002_0
(PROLYL-TRNA
SYNTHETASE (PRORS))		 1aql BILE-SALT ACTIVATED
LIPASE
(Bos
taurus) 		5 / 12 VAL A 460
GLU A 193
HIS A 435
THR A 397
GLY A 221
 None
 1.30A 5xiqA-1aqlA:
undetectable		 5xiqA-1aqlA:
20.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XIQ_D_HFGD1002_0
(PROLYL-TRNA
SYNTHETASE (PRORS))		 1aql BILE-SALT ACTIVATED
LIPASE
(Bos
taurus) 		5 / 12 VAL A 460
GLU A 193
HIS A 435
THR A 397
GLY A 221
 None
 1.32A 5xiqD-1aqlA:
undetectable		 5xiqD-1aqlA:
20.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EP4_A_DMEA601_1
(CHOLINESTERASE)		 1aql BILE-SALT ACTIVATED
LIPASE
(Bos
taurus) 		4 / 5 TYR A 125
GLU A 193
TYR A 427
HIS A 435
 None
 1.46A 6ep4A-1aqlA:
52.9		 6ep4A-1aqlA:
8.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EXI_C_ADNC502_1
(ADENOSYLHOMOCYSTEINA
SE)		 1aql BILE-SALT ACTIVATED
LIPASE
(Bos
taurus) 		3 / 3 LEU A 190
GLY A 192
PHE A 109
 None
 0.67A 6exiC-1aqlA:
3.4		 6exiC-1aqlA:
11.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MN8_A_HFGA603_0
(UNCHARACTERIZED
PROTEIN)		 1aql BILE-SALT ACTIVATED
LIPASE
(Bos
taurus) 		5 / 12 VAL A 460
GLU A 193
HIS A 435
THR A 397
GLY A 221
 None
 1.30A 6mn8A-1aqlA:
undetectable		 6mn8A-1aqlA:
20.52